Yamada Toshiko 山田とし子

… Alternative Names

OKABE Toshiko 岡部とし子

YAMADA Toshiko 山田とし子

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Researcher Number	20152564
Other IDs
Affiliation (Current)	2025: 相模女子大学短期大学部, その他部局等, 特任教授
Affiliation (based on the past Project Information) *help	2009 – 2011: Sagami Women's University, 栄養科学部, 教授 2001 – 2004: Yokohama City University, School of Medicine, Associate Professor, 医学部, 助教授 1999 – 2001: 横浜市立大学, 医学部, 講師 1994 – 1997: Yokohama City University, School of Medicine, Assistant Professor, 医学部, 講師
Review Section/Research Field	Principal Investigator Hygiene / Science and Engineering / Hygiene Except Principal Investigator Hygiene
Keywords	Principal Investigator 甲状腺ホルモン受容体 / 甲状腺ホルモン / 内分泌攪乱物質 / レポーターアッセイ / UAP1 / 難燃剤 / 4-1BB / 農薬 / 臭素化難燃剤 / DNAマイクロアレー … More / 甲状腺ホルモンレスポンスエレメント / thyroid hormone response element / estrogen receptor / reporter assay / endocrine disrupters / organohalogen compounds / thyroid hormone receptor / thyroid hormone / 環境汚染物質 / 有機ハロゲン態ハロゲン化合物 / エストロゲン受容体 / 内分泌攪乱化学物質 / 有機態ハロゲン化合物 / NAG cluster / GlcNAc-phosphate deacetyiase / GlcNAc kinase / anti-sperm antibody / AgX1 / UDP-Ν-acetylglucosamine / male infertility / 内分泌かく乱物質 / Agx-1 / AgX-1 / 精子運動率 / N-アセチルグルコサミン / NAGクラスター / GlcNAc-phosphate deacetylase / GlcNAc Kinase / 抗精子抗体 / AgXl / UDP-N-アセチルグルコサミン / 男性不妊症 / プロテアソーム阻害剤 / 培養細胞 / バイオアッセイ / 甲状腺ホルモン応答配列 / 蛍光強度 / GFP / 緑色蛍光タンパク質 / 環境保健 / ELISA / 有機態ヨウ素化合物 / シグナル伝達 / マイクロアレー … More Except Principal Investigator Candida albicans / dioxin / hydroxylated PCB / luciferase / reporter assay / T_3 / thyroid hormone response element / thyroid hormone receptor / endocrine disruptants / テトラサイクリン / レチノイン酸Xレセプター / DRO / direct repeat(DR)4 / ホルモンレスポンスエレメント / リポーターアッセイ / 甲状腺ホルモンレセプター / ダイオキシン / 水酸化PCB / ルシフェラーゼ / レポーターアッセイ / T3 / 甲状腺ホルモンレスポンスエレメント / 甲状腺ホルモン受容体 / 内分泌かく乱物質 / histidine kinase / beta-glucan / mRNA 5' triphosphatase / mRNA 5' guanylyltransferase / mRNA 5' capping enzyme / 5'-トリフォスファターゼ / ヒスチジンキナーゼ / β-グルカン / トリフォスファターゼ / グアニル酸転移酵素 / キャッピング酵素 / Cisplatin / Cell transformation / Oncogene / Promoter / Metallothionein / Leucine amino-peptidase / Clinical test / Individuality / 固体差 / シスプラチン / 細胞癌化 / 癌遺伝子 / プロモーター / メタロチオネイン / ロイシンアミノペプチダーゼ / 臨床検査値 / 個体差 Less

Basic studies for a novel validation system of thyroid hormone-like activities by chemicalsPrincipal Investigator
- Principal Investigator
  
  OKABE Toshiko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  Sagami Women's University
内分泌攪乱物質による(抗)甲状腺ホルモン様作用の検討と評価法の確立Principal Investigator
- Principal Investigator
  
  岡部とし子
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Yokohama City University
Development of bioassay system for evaluating the (anti-) thyroid hormone-like activity by various environmental contaminantsPrincipal Investigator
- Principal Investigator
  
  OKABE Toshiko
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  Yokohama City University
甲状腺ホルモン受容体を介した内分泌攪乱物質の生物作用の解析Principal Investigator
- Principal Investigator
  
  岡部とし子
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Science and Engineering
- Research Institution
  Yokohama City University
Involvement of UDP-GlcNAc biosynthesis in sexual dysfunctions caused by endocrine disrupting chemicalsPrincipal Investigator
- Principal Investigator
  
  OKABE Toshiko
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  Yokohama City University
Development of risk assessment system for human by environmental disruptants using nuclear hormone receptor
- Principal Investigator
  
  DOI Rikuo
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Institution
  Yokohama City University
ISOLATION OF mRNA 5'-CAPPING ENZYME FROM THE PATHOGENIC FUNGUS CANDIDA ALBICANS AND SCREENING FOR SPECIFIC INHIBITORS OF THE ENZYME
- Principal Investigator
  
  DOI Rikuo
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  YOKOHAMA CITY UNIVERSITY
Genetical and toxicological studies for evaluation of clinical tests in individualities
- Principal Investigator
  
  DOI Rikuo
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  Yokohama City University, School of Medicine

All 2011 2005 2004 2003

All Journal Article Presentation

[Journal Article] Modulation at a cellular level of the thyroid hormone receptor-mediated gene expression by 1,2,5,6,9,10-hexabromocyclododecane (HBCD), 4,4'-diiodobiphenyl (DIB), and nitrofen (NIP).2005
- Author(s)
  Yamada-Okabe, T et al.
- Journal Title
  
  Toxicology Letters 155
  
  Pages: 127-133
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570303
[Journal Article] Modulation at a cellular level of the thyroid hormone receptor-mediated gene expression by 1,2,5,6,9,10-hexabromocyclododecane (HBCD), 4,4' -diiodobiphenyl (DIB), and nitrofen (NIP)2005
- Author(s)
  Yamada-Okabe, T et al.
- Journal Title
  
  Toxicology Letters 155
  
  Pages: 127-133
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570303
[Journal Article] 2,3,7,8-tetrachlorodibenzo-p-dioxin augments the modulation of gene expression mediated by the thyroid hormone receptor.2004
- Author(s)
  Yamada-Okabe, T et al.
- Journal Title
  
  Toxicology and Applied Pharmacology 194
  
  Pages: 201-210
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570303
[Journal Article] 2,3,7,8-tetrachlorodibenzo-p-dioxin augments the modulation of gene expression mediated by the thyroid hormone receptor2004
- Author(s)
  Yamada-Okabe, T et al.
- Journal Title
  
  Toxicology and Applied Pharmacology 194
  
  Pages: 201-210
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570303
[Journal Article] Thyroid hormone induces the expression of 4-1BB and activation of caspases in a thyroid hormone receptor dependent manner.2003
- Author(s)
  Yamada-Okabe, T et al.
- Journal Title
  
  European journal of Biochemistry 270
  
  Pages: 3064-3073
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570303
[Journal Article] Thyroid hormone induces the expression of 4-1BB and activation of caspases in a thyroid hormone receptor dependent manner2003
- Author(s)
  Yamada-Okabe, T et al.
- Journal Title
  
  European Journal of Biochemistry 270
  
  Pages: 3064-3073
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570303
[Presentation] 受容体タンパク質の分解を指標とした甲状腺ホルモン様作用評価系の開発2011
- Author(s)
  岡部とし子、安井奈津美
- Organizer
  第81回日本衛生学会総会
- Year and Date
  2011-03-26
- Data Source
  KAKENHI-PROJECT-21590671
[Presentation] 受容体タンパク質の分解を指標とした甲状腺ホルモン様作用評価系の開発2011
- Author(s)
  岡部とし子
- Organizer
  第81回日本衛生学会総会
- Place of Presentation
  昭和大学(東京都)(東日本大震災のため中止)
- Year and Date
  2011-03-26
- Data Source
  KAKENHI-PROJECT-21590671

1. KASHIMA Yuji (50233705)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
2. SAKAI Haruya (20303555)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. DOI Rikuo (70091585)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. MATSUI Mitsuaki (00285115)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. IKEMI Yoshiaki (80106301)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. URANO Tsutomu (00213512)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Yamada Toshiko 山田 とし子

OKABE Toshiko 岡部 とし子

YAMADA Toshiko 山田 とし子

Research Projects

Research Products

Co-Researchers

Basic studies for a novel validation system of thyroid hormone-like activities by chemicalsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

内分泌攪乱物質による(抗)甲状腺ホルモン様作用の検討と評価法の確立Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of bioassay system for evaluating the (anti-) thyroid hormone-like activity by various environmental contaminantsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

甲状腺ホルモン受容体を介した内分泌攪乱物質の生物作用の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Involvement of UDP-GlcNAc biosynthesis in sexual dysfunctions caused by endocrine disrupting chemicalsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of risk assessment system for human by environmental disruptants using nuclear hormone receptor

Principal Investigator

Project Period (FY)

Research Category

Research Institution

ISOLATION OF mRNA 5'-CAPPING ENZYME FROM THE PATHOGENIC FUNGUS CANDIDA ALBICANS AND SCREENING FOR SPECIFIC INHIBITORS OF THE ENZYME

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Genetical and toxicological studies for evaluation of clinical tests in individualities

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Modulation at a cellular level of the thyroid hormone receptor-mediated gene expression by 1,2,5,6,9,10-hexabromocyclododecane (HBCD), 4,4'-diiodobiphenyl (DIB), and nitrofen (NIP).2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Modulation at a cellular level of the thyroid hormone receptor-mediated gene expression by 1,2,5,6,9,10-hexabromocyclododecane (HBCD), 4,4' -diiodobiphenyl (DIB), and nitrofen (NIP)2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] 2,3,7,8-tetrachlorodibenzo-p-dioxin augments the modulation of gene expression mediated by the thyroid hormone receptor.2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] 2,3,7,8-tetrachlorodibenzo-p-dioxin augments the modulation of gene expression mediated by the thyroid hormone receptor2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Thyroid hormone induces the expression of 4-1BB and activation of caspases in a thyroid hormone receptor dependent manner.2003

Author(s)

Journal Title

Description

Data Source

[Journal Article] Thyroid hormone induces the expression of 4-1BB and activation of caspases in a thyroid hormone receptor dependent manner2003

Author(s)

Yamada Toshiko 山田とし子

OKABE Toshiko 岡部とし子

YAMADA Toshiko 山田とし子