TAKAHASHI Yuji 高橋勇二

… Alternative Names

TAKAHASHI YUJI 高橋勇二

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Researcher Number	20154875
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2015 – 2017: 東京薬科大学, 生命科学部, 教授 2011 – 2013: 東京薬科大学, 生命科学部, 教授 2004 – 2007: 東京薬科大学, 生命科学部, 教授 2002: Tokyo University of Pharmacy and Life Science School of Life Science Professor, 生命科学部, 教授 1995 – 2001: TOKYO UNVERSITY OF PHARMACY AND LIFE SCIENCE, DEPARTMENT OF LIFE SCIENCE, ADDOCIATE PROFFESSOR, 生命科学部, 助教授 1994: 東京薬科大学, 生命科学部・環境生命科学科, 助教授 1993: 国立環境研究所, 環境健康部, 主任研究員
Review Section/Research Field	Principal Investigator Respiratory organ internal medicine / Embryonic/Neonatal medicine / Pediatrics / Food science / Applied biochemistry / Applied molecular and cellular biology / Respiratory organ internal medicine Except Principal Investigator 環境影響評価(含放射線生物学) / 環境保全
Keywords	Principal Investigator hypoxia / 転写調節因子 / 低酸素 / fetus / prolyl 4-hydroxylase / differential display / rat / ATF5 / ストレス応答 / ラット … More / 肺 / 神経内分泌細胞 / 細胞分化 / Shh / Notch / DANCE / Bax inhibitor-1 / ATF / CREB / fibroblast / phosphoglycerate mutase / Reoxygenation / 有機スズ / RT-PCR / 酸素 / 食欲 / 小胞体ストレス / 遺伝子欠損マウス / 内分泌撹乱化学物質 / 代謝異常 / 転写因子 / 肥満 / 視床下部 / cellular differentiation / pulmonary epithelial cells / Neuroendocrine cells / 神経内分泌 / コラーゲン / 肺上皮 / lung damage / cell differentiation / neuroendocrine cell / lung epithelium / Hes1 / Mash1 / 低酸素刺激 / 肺発達 / Neuroendocrine / 肺障害 / 肺神経内分泌細胞 / hyperosmotic stress / oxygen stress / Transcription Factor / stress response / Nrf-2 / アポトーシス / BAX / ストレス応答反応 / 高浸透圧ストレス / 酸素ストレス / 胎児 / oxygen sensor / 循環器 / 呼吸器 / 新生児 / F3 / Ba / GFP / エリスロポイエチン / センサー / プロリル水酸化酵素 / 胎仔 / 繊維芽細胞 / ディファレンシャルディスプレイ / 酸素センサー / phosphoglycerate mutase B / gene induction / Phosphoglycerate mutase / lysyl hydroxylase / RAT / PHOSPHOGLYCERATE MUTASE / PROLYL 4-HYDROXYLASE / DIFFERENTIAL DISPLAY / REOXYGENATION / HYPOXIA / Differential Display / 新生仔 / 酸素刺激 / Prolyl hydroxylase / prolyl hydroxy lase / differential Display / レンチウィルス / 飢餓応答 / 自閉症 / 社会性行動 / 多動 / 不安行動 / 学習行動 / 介在ニューロン / 糸球体 / 嗅球 / 自閉症スペクトラム / エストロゲン受容体 / ステロイドホルモン受容体 / エストロゲン / インポセックス / 巻き貝 / 発達 / グルタミルトランスペプチダーゼ … More Except Principal Investigator エストラジオール / アロマターゼ / 神経節 / トリブチルスズ / イボニシ / 遺伝子 / 耐性 / 殺虫剤 / ユスリカ Less

Abnormal energy metabolism induced by hypothalamic low-graded inflammationPrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Yuji
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Food science
- Research Institution
  Tokyo University of Pharmacy and Life Science
Starvation stress-responsive transcription factor is involved in the regulation of memory-independent social behavior of mousePrincipal Investigator
- Principal Investigator
  
  TAKAHASHI YUJI
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied biochemistry
- Research Institution
  Tokyo University of Pharmacy and Life Science
Cellular differentiation from human lung epithelial progenitor cells to pulmonary nuroendocrine cellsPrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Yuji
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Tokyo University of Pharmacy and Life Science
Choromatin modifier-associated cellular differentiation of pulmonary epithelial cells to neuroendocrine cellsPrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Yuji
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Tokyo University of Pharmacy and Life Sciences
巻き貝をモデルとした軟体動物に起こる内分泌撹乱の作用機構に関する研究Principal Investigator
- Principal Investigator
  
  高橋勇二
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Applied molecular and cellular biology
- Research Institution
  Tokyo University of Pharmacy and Life Science
Oxygen-stress induced gene expression in the perinatal lung of ratsPrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Yuji
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Tokyo University of Pharmacy Life Science
有機スズ化合物によるインポセックスの発症機構の解明と検出指標の開発に関する研究
- Principal Investigator
  
  三浦卓
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  Tokyo University of Pharmacy and Life Science
Identification of Oxygen Sensor Expressed in Newborn RatsPrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Yuji
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Tokyo University of Pharmacy and Life Science
昆虫の殺虫剤耐性遺伝子の探索とその指標性に関する研究
- Principal Investigator
  
  MIURA Takashi
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  環境保全
- Research Institution
  Tokyo University of Pharmacy and Life Science
Identification of Transcription Factors Expressed in Pulmonary Epithelium in Response to Oxygen Tension ShiftPrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Yuji
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Tokyo University of Pharmacy and Life Science
SCRENING OF IN NEW-BORN RAT LUNG GENES RESPONDING TO OXYGEN TENSION SHIFTPrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Yuji
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Tokyo University of Pharmacy and Life Science
肺deltaグルタミルトランスペプチダーゼの生後誘導における酵素刺激の役割に関する研究Principal Investigator
- Principal Investigator
  
  高橋勇二
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  National Institute for Environmental Studies

All 2014 2013 2012 2011 2005 Other

All Journal Article Presentation

[Journal Article] N-terminal hydrophobic amino acids of ATF5 confer IL-1β-induced stabilization2014
- Author(s)
  Abe T., Kojima M., Akanuma S., Iwashita H., Yamazaki T., Okuyama R., Ichikawa K., Umemura M., Nakano H., Takahashi S., and Takahashi Y.
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 289 Pages: 3888-3900
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23580141
[Journal Article] N-terminal hydrophobic amino acids of ATF5 confer IL-1b-induced stabilization2014
- Author(s)
  Abe T., Kojima M., Akanuma S., Iwashita H., Yamazaki T., Okuyama R., Ichikawa K., Umemura M., Nakano H., Takahashi S., and Takahashi Y.
- Journal Title
  
  J Biol Chem
  
  Volume: 289 Pages: 3888-3900
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23580141
[Journal Article] Phenolic diterpenes from rosemary suppress cAMP responsiveness of gluconeogenic gene promoters2013
- Author(s)
  Yun YS., Noda S., Shigemori G., Kuriyama R., Takahashi S., Umemura M., Takahashi Y., and Inoue H.
- Journal Title
  
  Phytother Res
  
  Volume: 27 Issue: 6 Pages: 906-910
- DOI
  10.1002/ptr.4794
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23580141, KAKENHI-PROJECT-23590310
[Journal Article] The 5'-untranslated region regulates ATF5 mRNA stability via nonsense-mediated mRNA decay in response to environmental stress,2013
- Author(s)
  Hatano M., Umemura M., Kimura N., Yamazaki T., Takeda H., Nakano H., Takahashi S., and Takahashi Y.
- Journal Title
  
  FEBS J
  
  Volume: 280 Pages: 4693-4707
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23580141
[Journal Article] The 5'-untranslated region regulates ATF5 mRNA stability via nonsense-mediated mRNA decay in response to environmental stress2013
- Author(s)
  Hatano M., Umemura M., Kimura N., Yamazaki T., Takeda H., Nakano H., Takahashi S., and Takahashi Y.
- Journal Title
  
  FEBS J
  
  Volume: 280 Issue: 18 Pages: 4693-4707
- DOI
  10.1111/febs.12440
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23580141, KAKENHI-PROJECT-23590310
[Journal Article] Detection of vertebrate-type sterid hormones and their converting activity in the neogastropid, Thais clavigera2012
- Author(s)
  Goto, Y., Kajiwara, M., Yanagisawa, Y., Hirose, H., Yoshimi, T., Umemura, M., Nakano, H., Takahashi, S., Shida, Y., Iguchi, T., Takahashi, Y., Miura T.
- Journal Title
  
  J. Mol. Studies
  
  Volume: 78 Issue: 2 Pages: 197-204
- DOI
  10.1093/mollus/eys001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23580141, KAKENHI-PROJECT-23590310
[Journal Article] Homeobox B3, FoxA1 and FoxA2 interactions in epithelial lung cell differentiation of the multipotent M3E3/C3 cell line.2005
- Author(s)
  T Yoshimi, N Nakamura, S Shimada, K Iguchi, F Hashimoto, K Mochitate, Y Takahashi, T Miura
- Journal Title
  
  Eur J Cell Biol 84(5)
  
  Pages: 555-566
- Data Source
  KAKENHI-PROJECT-16590764
[Presentation] 転写因子ATF5による嗅覚受容体の発現調節2014
- Author(s)
  金子将人、雨宮ゆう子、中野春男、梅村真理子、高橋滋、高橋勇二
- Organizer
  日本農芸化学会2014年度大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23580141
[Presentation] マウス鋤鼻細胞の増殖とアポトーシスに関与する転写因子ATF52014
- Author(s)
  鈴木誠人、飯田吉剛、青木満里恵、笹川洋、中野春男、梅村真理子、高橋滋、高橋勇二
- Organizer
  日本農芸化学会2014年度大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23580141
[Presentation] ATF5欠損マウスの脳内モノアミン量の解析2013
- Author(s)
  森直人、梅村真理子,松崎彩子,中野春男,高橋滋,高橋勇二
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23580141
[Presentation] マウス鋤鼻器における転写因子ATF5の機能解析2013
- Author(s)
  飯田吉剛,鈴木誠人,青木満里恵,笹川洋,中野春男,梅村真理子,高橋滋,高橋勇二
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23580141
[Presentation] 軟体動物の組織再生に関わるレチノイン酸シグナルおよび幹細胞関連因子の解析2013
- Author(s)
  中間翼、関百恵、渡邊弘明、伊東翼、金子浩子、梅村真理子、中野春男、高橋滋、高橋勇二
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23580141
[Presentation] IL-1bによるATF5タンパク質安定化の免疫応答における役割2013
- Author(s)
  阿部貴則、岩下弘実、奥山隆一、山崎高志、高橋滋、高橋勇二
- Organizer
  日本生化学会関東支部例会
- Place of Presentation
  甲府市
- Data Source
  KAKENHI-PROJECT-23580141
[Presentation] ATF5/C/EBPγheterodimer regulates sodium-arsenite induced DR5 gene expression in human hepatoma cells2012
- Author(s)
  山﨑高志、阿部貴則、中野春男、梅村真理子、高橋滋、高橋勇二
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  博多
- Data Source
  KAKENHI-PROJECT-23580141
[Presentation] Involvement of retinoic acid pathway in tissue regeneration of Thais clavigera2012
- Author(s)
  Watanabe, H., Itou, T., Nagasawa, K., Kaneko, H., Mizukami, K., Aya Saiga, A., Nakano, H., Umemura, M., Shigeru Takahashi, S., Takahashi, Y.
- Organizer
  Gordon Research Conference on Environmental Endocrine Disruptors
- Place of Presentation
  New Hampshire, USA
- Data Source
  KAKENHI-PROJECT-23580141
[Presentation] 環境ストレスによるC/EBPγmRNAの安定化制御2012
- Author(s)
  大川佳子、山﨑高志、中野春男、梅村真理子、高橋滋、高橋勇二
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  博多
- Data Source
  KAKENHI-PROJECT-23580141
[Presentation] ATF5 mRNA発現調節機構における翻訳開始点の変動とNMDの寄与2012
- Author(s)
  幡野仁哉,梅村真理子,鈴木実菜子,中野春男,高橋滋,高橋勇二
- Organizer
  日本農芸化学会2012年度大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23580141
[Presentation] The 5'-untranslated region regulates the stability of ATF5mRNA by nonsense-mediated mRNA decay2011
- Author(s)
  Umemura, M., Hatano, M., Kimura, N., Yamazaki, T., Takeda, H., Nakano, H., Takahashi, S., Takahashi, Y.
- Organizer
  Cold spring harbor laboratory the 2011 meeting on eukaryotic mRNA processing
- Place of Presentation
  New York, USA
- Data Source
  KAKENHI-PROJECT-23580141
[Presentation] Regulation of C/EBPγmRNA stability by environmental stresses2011
- Author(s)
  Yamazaki, T., Okawa, Y.,Watanabe, R., Murakoso, S., Nakano, H., Takahashi, S., Takahashi, Y.
- Organizer
  Cold spring harbor laboratory the 2011 meeting on eukaryotic mRNA processing
- Place of Presentation
  New York, USA
- Data Source
  KAKENHI-PROJECT-23580141
[Presentation] 嗅覚系の発達におけるATF5の機能解明2011
- Author(s)
  恒松加奈子、梅村真理子、清水悠介、中野春男、高橋滋、東浦康友、岡部勝、高橋勇二
- Organizer
  第34回に本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23580141
[Presentation] IL-1bによるATF5タンパク質安定化の免疫応答における役割
- Author(s)
  阿部貴則、岩下弘実、奥山隆一、山崎高志、高橋滋、高橋勇二
- Organizer
  日本生化学会関東支部例会
- Place of Presentation
  甲府市
- Data Source
  KAKENHI-PROJECT-23580141

1. TAKAHASHI Shigeru (10266900)

# of Collaborated Projects: 7 results

# of Collaborated Products: 1 results
2. MIURA Takashi (70013323)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. HIROSE Hidenori (80398817)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 吉見立也 (30277256)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. MARIKO Umemura (30521489)

# of Collaborated Projects: 1 results

# of Collaborated Products: 17 results
6. HARUO Nakano (60601870)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results

TAKAHASHI Yuji 高橋 勇二

TAKAHASHI YUJI 高橋 勇二

Research Projects

Research Products

Co-Researchers

Abnormal energy metabolism induced by hypothalamic low-graded inflammationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Starvation stress-responsive transcription factor is involved in the regulation of memory-independent social behavior of mousePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Cellular differentiation from human lung epithelial progenitor cells to pulmonary nuroendocrine cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Choromatin modifier-associated cellular differentiation of pulmonary epithelial cells to neuroendocrine cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

巻き貝をモデルとした軟体動物に起こる内分泌撹乱の作用機構に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Oxygen-stress induced gene expression in the perinatal lung of ratsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

有機スズ化合物によるインポセックスの発症機構の解明と検出指標の開発に関する研究

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of Oxygen Sensor Expressed in Newborn RatsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

昆虫の殺虫剤耐性遺伝子の探索とその指標性に関する研究

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of Transcription Factors Expressed in Pulmonary Epithelium in Response to Oxygen Tension ShiftPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

SCRENING OF IN NEW-BORN RAT LUNG GENES RESPONDING TO OXYGEN TENSION SHIFTPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

肺deltaグルタミルトランスペプチダーゼの生後誘導における酵素刺激の役割に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] N-terminal hydrophobic amino acids of ATF5 confer IL-1β-induced stabilization2014

Author(s)

Journal Title

TAKAHASHI Yuji 高橋勇二

TAKAHASHI YUJI 高橋勇二