AKIRA Hiratsuka 平塚明

… Alternative Names

平塚明ヒラツカアキラ

HIRATSUKA Akira 平塚明

HIRATSUKA Akira Assistan 平塚明

Less

Researcher Number	20165179
Other IDs
External Links
Affiliation (Current)	2025: 東京薬科大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2004 – 2005: 東京薬科大学, 薬学部, 教授 2003: 東京薬科大学, 薬学部, 助教授 2002: 東京薬科大学, 薬学部, 教授 1999 – 2001: 東京薬科大学, 薬学部, 助教授 1994 – 1996: 東京薬科大学, 薬学部, 助教授 … More 1992: Tokyo College of Pharmacy, Hygienic Chemistry, Lecture, 薬学部, 構師 1990 – 1991: 東京薬科大学, 薬学部, 講師 1986 – 1988: 東京薬科大学, 薬学部, 講師 Less
Review Section/Research Field	Principal Investigator Biological pharmacy Except Principal Investigator Biological pharmacy
Keywords	Principal Investigator glutathione S-transferase / グルタチオン抱合 / ラット / グルタチオンS-トランスフェラーゼ / Clone 9 / stereoselectivity / 肝 / 脂質過酸化 / 立体選択性 / UV-B … More / glutathione conjugation / rat / detoxification / metabolism / hydroperoxide / cell toxicity / 4-hydroxynonenal / PC12 / 細胞毒性 / 還元反応 / エナンチオマー / ヒト / HepG2 / ヒドロペルオキシド / リポキシゲナーゼ / アラキドン酸 / リノール酸 / 4-ヒドロキシノネナール / guinea pig / lipid peroxidation / 4-hydroxy-2(E)-nonenal / 4-ヒドロキン-2(E)-ノネナール / 発現誘導 / 皮膚 / 酵素阻害 / 酸化ストレス / モルモット / 4-ヒドロキシ-2(E)-ノネナール / liver / purification / glutathione peroxidase activity / dichloromethane / Theta-class / 発現 / クローニング / Theta-Class / Metabolism / Carcinogen / Mouse / Rat / Glutathione S-transterase / Theta クラス / 肝臓 / 精製 / グルタチオンペルオキシダーゼ活性 / ジクロルメタン / Thetaクラス … More Except Principal Investigator 脂質過酸化物 / 脂肪酸ヒドロペルオキシド / 脂質過酸化 / Leukotriene A_4 / Glutathione peroxidase / Epoxide / Fatty acid hydroperoxide / Microsomal lipid peroxidation / Active oxygen / アフラトキシン【B_1】 / ジヒドロベンゾ〔a〕ピレン / 膜脂質アラキドン酸 / 脂質パーオキシラジカル / 肝ミクロゾームの脂質過酸化 / 抗酸化剤 / 変異原性エポキシド / パーオキシラジカル / 肝小胞体膜リン脂質 / 活性酸素 / 肝ミクロゾーム脂質過酸化 / エポキシドヒドロラーゼ / ロイコトリエンA_4 / グルタチオンペルオキシダーゼ / エポキシド / ミクロゾーム脂質過酸化 / 活性酵素 / Aging / Marker Substanec in Aging / Cholesterol Hydroperoxide / Phospholipid Hydroperoxide / Glutathione S-Transferase / Biomembrane / Lipid Peroxidation / Oxygen Free Radical / グルタチオントランスフェラ-ゼ / 肝細胞質 / グルタチオンペルオキシダ-ゼ / グルタチオン / 酸素フリ-ラジカル / 肝ミクロソ-ム / cDNAクローニング / グルタチオンペルオキシダーゼ活性 / 生体膜防御機構 / 過酸化脂質 / ミクロソーム / ラット肝 / 老化 / 加齢マーカー物質 / コレステロールヒドロペルオキシド / リン脂質ヒドロペルオキシド / グルタチオンS-トランスフェラーゼ / 生体膜 / 酸素フリーラジカル Less

Cytotoxicity of 4-hydroxynonenal enantiomers and stereoselectivity in those detoxification metabolismPrincipal Investigator
- Principal Investigator
  
  HIRATSUKA Akira
- Project Period (FY)
  2002 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tokyo University of Pharmacy and Life Sciences
The expression mechanism of glutathione S-transferase in UV-B irradiated skinPrincipal Investigator
- Principal Investigator
  
  AKIRA Hiratsuka
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tokyo University of Pharmacy and Life Science
The role of novel type of glutathione S-transferase Yrs-Yrs in animal bodyPrincipal Investigator
- Principal Investigator
  
  HIRATSUKA Akira
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tokyo University of Pharmacy and Life Science
A Novel Mechanism for Protecting of Biomembrane from Oxidative Disorder by Oxygen Free Radicals
- Principal Investigator
  
  WATABE Tadashi
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tokyo College of Pharmacy
Oxidation of xenobiotics by active peroxyradicals derived from lipids of hepatic endoplasmic reticulum
- Principal Investigator
  
  WATABE Tadashi Professor
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tokyo College of Pharmacy

All 2004 2003

All Journal Article

[Journal Article] The induction mechanism of glutathione transferase by ultraviolet light, and its toxicological significance2004
- Author(s)
  Akira Hiratsuka
- Journal Title
  
  Environmental Mutagen Research 26
  
  Pages: 107-115
- NAID
  10013956800
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14572071
[Journal Article] 紫外線によるグルタチオン転移酵素の誘導機構とその毒性学的意義2004
- Author(s)
  平塚明
- Journal Title
  
  Environ.Mutagen.Res. 26
  
  Pages: 107-107
- NAID
  10013956800
- Data Source
  KAKENHI-PROJECT-14572071
[Journal Article] Clinical implications of the genetic polymorphisms in Phase II drug-metabolizing enzymes and dihydropyrimidine dehydrogenase2003
- Author(s)
  Akira Hiratsuka
- Journal Title
  
  Japanese Journal of Clinical Pharmacology and Therapeutics 34(4)
  
  Pages: 163-170
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14572071

1. WATABE Tadashi (00057316)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. OKUDA Haruhiro (30160807)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. OGURA Kenichiro (10185564)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

AKIRA Hiratsuka 平塚 明

平塚 明 ヒラツカ アキラ

HIRATSUKA Akira 平塚 明

HIRATSUKA Akira Assistan 平塚 明

Research Projects

Research Products

Co-Researchers

Cytotoxicity of 4-hydroxynonenal enantiomers and stereoselectivity in those detoxification metabolismPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The expression mechanism of glutathione S-transferase in UV-B irradiated skinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of novel type of glutathione S-transferase Yrs-Yrs in animal bodyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A Novel Mechanism for Protecting of Biomembrane from Oxidative Disorder by Oxygen Free Radicals

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Oxidation of xenobiotics by active peroxyradicals derived from lipids of hepatic endoplasmic reticulum

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] The induction mechanism of glutathione transferase by ultraviolet light, and its toxicological significance2004

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] 紫外線によるグルタチオン転移酵素の誘導機構とその毒性学的意義2004

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Clinical implications of the genetic polymorphisms in Phase II drug-metabolizing enzymes and dihydropyrimidine dehydrogenase2003

Author(s)

Journal Title

Description

Data Source

AKIRA Hiratsuka 平塚明

平塚明ヒラツカアキラ

HIRATSUKA Akira 平塚明

HIRATSUKA Akira Assistan 平塚明