Takahiro Isono 礒野高敬

… Alternative Names

ISONO Takahiro 礒野高敬

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Researcher Number	20176259
Other IDs
Affiliation (based on the past Project Information) *help	2015 – 2019: 滋賀医科大学, 実験実習支援センター, 准教授 2013: 滋賀医科大学, 医学部, 准教授 2012 – 2013: 滋賀医科大学, 実験実習支援センター, 准教授 2007 – 2008: 滋賀医科大学, 医学部, 准教授 2003 – 2006: 滋賀医科大学, 医学部, 助教授
Review Section/Research Field	Principal Investigator Tumor diagnostics / Urology Except Principal Investigator Urology / Circulatory organs internal medicine / Laboratory medicine / Biological Sciences
Keywords	Principal Investigator TAK1 / transcript variants / periostin / 治療薬ターゲット / 治療ターゲット / アポトーシス / 活性酸素 / ミトコンドリア / 新規分子標的 / 予後予測マーカー … More / 遺伝子発現解析 / 栄養枯渇耐性 / 腎癌 / invasiveness / metastasis / cancer cells / bladder cancer / 浸潤 / 転移 / 癌細胞 / 膀胱癌 … More Except Principal Investigator HSP27 / MALDI-TOF MS / 分子標的治療 / リン酸化 / 増殖抑制機構 / 細胞周期関連遺伝子 / γ-グルタミルシクロトランスフェラーゼ / 癌関連タンパク / 抗腫瘍メカニズム / メタボローム解析 / トランスクリプトーム解析 / γ-グルタミルシクロトランスフェラーぜ / 小胞体ストレス / グルコース枯渇 / 血管新生阻害剤 / 腎細胞がん / VHL遺伝子 / 治療耐性 / 腎がん / 糖枯渇 / 遺伝子発現 / 次世代シーケンサー / 腎癌 / phosphorylation / HSP 20 / alpha B crystallin / congestive heart failure / proteomics / small heat shock protein / プロテオーム / HSP20 / alpha B crystalin / 心不全 / プロテオーム解析 / 癌 / siRNA / バイオマーカー / 臨床病理 / メチルトランスフェラーゼ / エピジェネティックス / SOX2 / 胎児性癌 / 腫瘍マーカー / 化学療法 / 幹細胞遺伝子 / DNMT3L / メチレーション / 精巣腫瘍 / 精巣腫瘍のエピジェネティックス / 腫瘍学 / 癌抑制遺伝子 / 転移 / 浸潤 / periostin / 尿路上皮癌 / ケモタキシス / CDK2 / 細胞周期 / ヌクレオホスミン / P2受容体 / 細胞外ATP / 分化 / 脂肪細胞 Less

Elucidation of the mechanism of antitumor effect in inhibition of GGCT expression using integrated omics analysis
- Principal Investigator
  
  Kubota Shigehisa
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Shiga University of Medical Science
The exploratory research of biomarkers of renal cell carcinomas for therapeutic drugs based on the evidence of global transcriptome analysis.Principal Investigator
- Principal Investigator
  
  Isono Takahiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor diagnostics
- Research Institution
  Shiga University of Medical Science
Novel biomarker and therapeutic target in the targeted therapy for the patients with metastatic renal cell cancer
- Principal Investigator
  
  Takeshi Yuasa
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Japanese Foundation for Cancer Research
Application of novel clinicopathological biomarkers to cancer treatment
- Principal Investigator
  
  OKABE Hidetoshi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Shiga University of Medical Science
Analysis and clinical application of DNMT3L, a novel marker for human embryonal carcinoma
- Principal Investigator
  
  OKAMOTO Keisei
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Shiga University of Medical Science
Molecular mechanisms of the suppression of invasion and metastasis by periostin in urothelial carcinoma
- Principal Investigator
  
  KIM Chul Jang
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Shiga University of Medical Science
P2受容体刺激による前駆脂肪細胞の分化誘導因子に対する感受性増大機構の解明
- Principal Investigator
  
  尾松万里子
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Shiga University of Medical Science
Analysis of the mechanism of suppression of invasiveness and metastasis by periostin gene in bladder cancerPrincipal Investigator
- Principal Investigator
  
  ISONO Takahiro
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Shiga University of Medical Science
Proteome analysis reveals molecular alternations of cardiac protein expression via Angiotensin-II in congestive heart failure
- Principal Investigator
  
  WADA Atsuyuki
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Shiga University of Medical Science

All 2017 2016 2015 2014 2013 2012 2011 2010 2008 2007 2004 2003 Other

All Journal Article Presentation

[Journal Article] Hydroxyl-HIF2-alpha is potential therapeutic target for renal cell carcinomas.2016
- Author(s)
  American Journal of Cancer Research Volume 6, Issue 10, 2016, Pages 2263-2276 Open Access Hydroxyl-HIF2-alpha is potential therapeutic target for renal cell carcinomas (Article) Isono, T. , Chano, T., Yoshida, T., Kageyama, S., Kawauchi, A., Suzaki, M., Yuasa, T.
- Journal Title
  
  American Journal of Cancer Research
  
  Volume: 6 Pages: 2263-2276
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K06854
[Journal Article] Therapeutic inhibition of mitochondrial function induces cell death in starvation-resistant renal cell carcinomas.2016
- Author(s)
  Isono T, Chano T, Yonese J, Yuasa T.
- Journal Title
  
  Sci Rep
  
  Volume: 6 Issue: 1 Pages: 25669-25669
- DOI
  10.1038/srep25669
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460648, KAKENHI-PROJECT-25293130, KAKENHI-PROJECT-15K06854, KAKENHI-PROJECT-16K11035
[Journal Article] Glucose deprivation induces G2/M transition-arrest and cell death in N-GlcNAc2-modified protein-producing renal carcinoma cells2014
- Author(s)
  Isono T, Chano T, Kitamura A, Yuasa T
- Journal Title
  
  PLoS One
  
  Volume: 9(5)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390148
[Journal Article] Study of Global Transcriptional Changes of N-GlcNAc2 Proteins-Producing T24 Bladder Carcinoma Cells under Glucose Deprivation2013
- Author(s)
  Isono T, Chano T, Okabe H, Suzaki M
- Journal Title
  
  PLoS One
  
  Volume: 8(4)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390148
[Journal Article] Study of global transcriptional changes of N-GlcNAc2 proteins-producing T24 bladder carcinoma cells under glucose deprivation.2013
- Author(s)
  Isono T, Chano T, Okabe H, Suzaki M.
- Journal Title
  
  PLoS One.
  
  Volume: 8(4) Issue: 4 Pages: e60397-e60397
- DOI
  10.1371/journal.pone.0060397
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390148, KAKENHI-PROJECT-23590395, KAKENHI-PROJECT-24659272, KAKENHI-PROJECT-25293130
[Journal Article] A global transcriptome analysis of a dog model of congestive heart failure with the human genome as a reference.2012
- Author(s)
  Isono T, Matsumoto T, Wada A, Suzaki M, Chano T.
- Journal Title
  
  J Card Fail.
  
  Volume: 18(11) Issue: 11 Pages: 872-878
- DOI
  10.1016/j.cardfail.2012.09.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390148, KAKENHI-PROJECT-24659272
[Journal Article] A global transcriptome analysis of a dog model of congestive heart failure with the human genome as a reference2012
- Author(s)
  Isono T, Matsumoto T, Wada A, Suzaki M, Chano T
- Journal Title
  
  J Card Fail
  
  Volume: 18(1) Pages: 872-878
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390148
[Journal Article] RB1CC1 activates the p16 promoter through the interaction with hSNF52011
- Author(s)
  Ochi Y, Chano T, Ikebuchi K, Inoue H, Isono T, Arai A, Tameno H, Shimada T, Hisa Y, Okabe H
- Journal Title
  
  Oncol Rep
  
  Volume: 26(4) Pages: 805-812
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390148
[Journal Article] RBCC1 activates the p16 promoter through the interaction with hSNF52011
- Author(s)
  Ochi, Y., et al
- Journal Title
  
  Oncol.Rep.
  
  Volume: 26 Pages: 805-812
- DOI
  10.3892/or.2011.1329
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590437, KAKENHI-PROJECT-21592041, KAKENHI-PROJECT-23390148
[Journal Article] Role of alternativesplicing of periostin in human bladder carcinogenesis2008
- Author(s)
  Kim CJ, Isono T, Tambe Y, Chano T, Okabe H, Okada Y, Inoue H
- Journal Title
  
  Int J Oncol 32
  
  Pages: 161-169
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591843
[Journal Article] Role of alternative splicing of periost in in human bladder carcinogenesis2008
- Author(s)
  Kim CJ, Isono T, Tambe Y, Chano T, Okabe H, Okada Y, Inoue H.
- Journal Title
  
  Int J Oncol 32
  
  Pages: 161-169
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591843
[Journal Article] A novel tumor-related protein,C70rf24,identified by proteome differential display of bladder urothelial carcinoma2007
- Author(s)
  Kageyama S, Iwaki H, Inoue H, Isono T, Yuasa T, Nogawa M, Maekawa T, Ueda M, Kajita Y, Ogawa O, Toguchida J, Yoshiki T.
- Journal Title
  
  Proteomics Clin Appl 1
  
  Pages: 192-199
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591843
[Journal Article] A novel tumor-related protein, C7orf24, identified by proteome differential display of bladder urothelial carcinoma2007
- Author(s)
  Kageyama S, Iwaki H, Inoue H, Isono T, Yuasa T, Nogawa M, Maekawa T, Ueda M,Kajita Y, Ogawa O, Toguchida J, Yoshiki T
- Journal Title
  
  Proteimics Clin Appl 1
  
  Pages: 192-199
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591843
[Journal Article] Tumor prone phenotype of mice deficient in a novel apoptosis-induced gene2007
- Author(s)
  Tambe Y, Yoshioka-Yamashita A, Mukaisho K, Haraguchi S, Chano T, Isono T, Kawai T, Suzuki Y, Kushima R, Tattori T, Goto M, Yamada S, Kiso M, Saga Y, Inoue H
- Journal Title
  
  drs. Carcinogenesis 28
  
  Pages: 777-784
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591843
[Journal Article] Suppression of viral replication by stress-inducible GADD34 protein via the mammalian serine/threonine protein kinase mTOR pathway2007
- Author(s)
  Minami K, Tambe Y, Watanabe R, Isono T,Haneda M, Isobe K, Kobayashi K, Hino O, Okabe H, Chano T, Inoue H
- Journal Title
  
  J Virol 81
  
  Pages: 11106-11115
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591843
[Journal Article] Tumor prone phenotype of mice deficient in a novel apoptosis'induced gene,drs2007
- Author(s)
  Tambe Y, Yosbioka-Yamashita A, Mukaisho K, Haraguchi S, Chano T, Isono T, Kawai T, Suzuki Y, Kushima R, Hattori T, Goto M, Yamada S, Kiso M, Saga Y, Inoue H.
- Journal Title
  
  Carcinogenesis 28
  
  Pages: 777-784
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591843
[Journal Article] GADD34 inhibitsmammalian target of rapamycinsignaling survival under bioenergeticstress2007
- Author(s)
  Watanabe R, Tambe Y, Inoue H, Isono T,Haneda M, Isobe K, Kobayashi T, Hino O,Okabe H, Chano T
- Journal Title
  
  Int J Mol Med 19
  
  Pages: 475-483
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591843
[Journal Article] Up-regulation of urinary UP III mRNA levels in vesicoureteral reflux patients : potential application as a screening test for vesicoureteral reflux2007
- Author(s)
  Iwaki H, Johnin K, Kageyama S, Kim CJ, Isono T, Yoshiki T
- Journal Title
  
  Int Jurol 14
  
  Pages: 918-923
- NAID
  10019947823
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591843
[Journal Article] Up-regulation of urinary UP III mRNA levels in vesicoureteral reflux patients: potential application as a screening test for vesicoureteral reflux2007
- Author(s)
  Iwaki H, Johnin K, Kageyama S, Kim CJ, Isono T, Yoshiki T.
- Journal Title
  
  Int J Urol 14
  
  Pages: 918-923
- NAID
  10019947823
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591843
[Journal Article] Suppression of viral replication by stress-inducible GADD34 protein via the mammalian serine/threonione protein kinase mTOR pathway2007
- Author(s)
  Minami K, Tambe Y, Watanabe R, Isono T, Haneda M, Isobe K, Kobayashi K, Hino O, 0kabe H, Chano T, Inoue H.
- Journal Title
  
  J Virol 81
  
  Pages: 11106-11115
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591843
[Journal Article] The contribution of vascular NAD(P)H oxidase to endothelial dysfunction in heart failure and the therapeutic effects of HMG-CoA reductase inhibitor.2004
- Author(s)
  T.Takayama, A.Wada, T.Tsutamoto, M.Ohnishi, M.Fujii, T.Isono, M.Horie
- Journal Title
  
  Circulation J 68(10)
  
  Pages: 1067-1075
- NAID
  110002695990
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590736
[Journal Article] Contribution of vascular NAD(P)H oxidase to endothelial dysfunction in heart failure and the therapeutic effects of HMG-CoA reductase inhibitor.2004
- Author(s)
  Takayama T, Wada A, Tsutamoto T, Ohnishi M, Fujii M, Isono T, _Horie M
- Journal Title
  
  Circ J. 68(11)
  
  Pages: 1067-1075
- NAID
  110002695990
- Data Source
  KAKENHI-PROJECT-15590736
[Journal Article] The contribution of vascular NAD(P)H oxidase to endothelial dysfunction in heart failure and the therapeutic effects of HMG-CoA reductase inhibitor2004
- Author(s)
  T.Takayama, A.Wada, T.Tsutamoto, M.Ohnishi, M.Fujii, T.Isono, M.Horie
- Journal Title
  
  Circulation J 68(11)
  
  Pages: 1067-1075
- NAID
  110002695990
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590736
[Journal Article] Chymase inhibition prevents cardiac fibrosis and improves diastolic dysfunction in the progression of heart failure.2003
- Author(s)
  Matsumoto T, Wada A, Tsutamoto T, Ohnishi M, Isono T, Kinoshita M
- Journal Title
  
  Circulation. 107(20)
  
  Pages: 2555-2558
- Data Source
  KAKENHI-PROJECT-15590736
[Journal Article] Chymase inhibition prevents cardiac fibrosis and improves diastolic dysfunction in the progression of heart failure2003
- Author(s)
  T.Matsumoto, A.Wada, T.Tsutamoto, M.Ohnishi, T.Isono, M.Kinoshita
- Journal Title
  
  Circulation 107(20)
  
  Pages: 2555-2558
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590736
[Journal Article] Chymase inhibition prevents cardiac fibrosis and improves diastolic dysfunction in the progression of heart failure2003
- Author(s)
  T.Matsumoto, A.Wada, T.Tsutamoto, M.Ohnishi, T.Isono, M.Kinoshita
- Journal Title
  
  Circulation 107
  
  Pages: 2555-2558
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590736
[Journal Article] The Drs tumor suppressor is involved in the maturation precess of autophagy induced by low serum
- Author(s)
  Tambe Y, Yamamoto A, Isono T, Chano T, Fukuda M, Inoue H
- Journal Title
  
  Cancer Letters (In press)(掲載確定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591843
[Journal Article] Cyclin Dlb variant promotes cell invasiveness independent of binding to CDK4 in human bladder cancer cells.
- Author(s)
  Kim CT, Nishi K, Isono T, Okuyama Y, Tambe Y, Okada Y, Inoue H
- Journal Title
  
  Mol Carcinogenesis (In press)(掲載確定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591843
[Journal Article] The Drs tumor suppressor is involved in the maturation process of antophagy induced by low serum
- Author(s)
  Tambe Y, Yamamoto A, Isono T, Chano T, Fukuda M, Inoue H
- Journal Title
  
  Cancer Lett (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591843
[Journal Article] Suppression of cell invasiveness by periostin via TAB1/TAK1
- Author(s)
  Isono T, Kim CJ, Ando Y, Sakurai H, Okada Y, Inoue H
- Journal Title
  
  Int J Oncol (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591843
[Journal Article] Cyclin D1b variant promotes cell invasiveness independent of binding to CDK4 in human bladder cancer cells
- Author(s)
  Kim CJ, Nishi K, Isono T, Okuyama Y, Tambe Y, Okada Y, Inoue H
- Journal Title
  
  Mol Carcinog (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591843
[Presentation] 遺伝子発現解析データのエビデンスに基づいた腎がんの診断マーカーと治療分子標的の探索2017
- Author(s)
  礒野高敬・湯浅健
- Organizer
  第４０回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-15K06854
[Presentation] Deprivation-resistant renal cell carcinomas expressed TRAIL and evaded the apoptotic cell death through TRAIL by HIF2.2017
- Author(s)
  礒野高敬
- Organizer
  第７７回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15K06854
[Presentation] Hydroxyl-HIF2-alphaの阻害は栄養枯渇耐性腎癌細胞に細胞死を誘導できる2016
- Author(s)
  礒野高敬、茶野徳宏、湯浅健
- Organizer
  第７５回日本癌学会学術総会
- Place of Presentation
  横浜パシフィコ（神奈川県・横浜）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15K06854
[Presentation] HIF2-alphaの阻害は栄養枯渇耐性腎癌細胞に細胞死を誘導できる2015
- Author(s)
  礒野高敬、茶野徳宏、湯浅健
- Organizer
  第３8回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド（兵庫県・神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K06854
[Presentation] ミトコンドリアの品質阻害はグルコース枯渇耐性腎癌細胞に細胞死を誘導する2015
- Author(s)
  礒野高敬、茶野徳宏、湯浅健
- Organizer
  第７４回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県・名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K06854
[Presentation] DNMT3L is a novel marker and essential for the growth of human embryonal carcinoma2010
- Author(s)
  Hiroshi Ushida, Kahori Minami, Tokuhiro Chano, Takahiro Kawakami, Hidetoshi Okabe, Yusaku Okada and Keisei Okamoto
- Organizer
  The 27th Japan-Korea Urological Congress
- Data Source
  KAKENHI-PROJECT-22390303
[Presentation] Periostin associates with TAB1 to activates TAK1 and suppresses cell invasiveness2008
- Author(s)
  Isono T, Kim CJ, Sakurai H, Okada Y, Tambe Y, Inoue H
- Organizer
  第67回日本癌学会総会
- Place of Presentation
  名古屋市
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-19591843
[Presentation] Splicing variant cyclin Dlbによる膀胱癌細胞の悪性化促進の解析2008
- Author(s)
  井上寛一, 西香代子, 奥山雄介, 旦部幸博, 岡田裕作, 礒野高敬, 金哲將
- Organizer
  第31回日本分子生物学会
- Place of Presentation
  神戸市
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-19591843
[Presentation] Cyclin Dlb variant enhances cell invasiveness of human bladder cancer cells2008
- Author(s)
  Kim CJ, Isono T, Tambe Y, Okada Y, Inoue H
- Organizer
  第67回日本癌学会総会
- Place of Presentation
  名古屋市
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-19591843
[Presentation] Periostin associates with TAB1 to activate TAK1 and suppresses cell invasiveness2008
- Author(s)
  Isono T, Kim CJ, Sakurai H, Okada Y, Tambe Y, Inoue H
- Organizer
  第67回日本癌学会総会
- Place of Presentation
  名古屋市
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-19591843
[Presentation] Periostinによる癌の浸潤・転移抑制機構の解析2008
- Author(s)
  礒野高敬, 金哲將, 安藤幸宏, 櫻井宏明, 山本章嗣, 井上寛一
- Organizer
  第31回日本分子生物学会
- Place of Presentation
  神戸市
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-19591843
[Presentation] Splicing variant cyclin D1bによる膀胱癌細胞の悪性化促進の解析2008
- Author(s)
  井上寛一, 西香代子, 奥山雄介, 旦部幸博, 岡田裕作, 礒野高敬, 金哲將
- Organizer
  第31回日本分子生物学会
- Place of Presentation
  神戸市
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-19591843
[Presentation] Cyclin D1b variant enhances cell invasiveness of human bladder cancer cells2008
- Author(s)
  Kim CJ, Isono T, Tambe Y, Okada Y, Inoue H
- Organizer
  第67回日本癌学会総会
- Place of Presentation
  名古屋市
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-19591843
[Presentation] Periostin による癌の浸潤・転移抑制機構の解析2008
- Author(s)
  礒野高敬, 金哲將, 安藤幸宏, 櫻井宏明, 山本章嗣, 井上寛一
- Organizer
  第31回日本分子生物学会
- Place of Presentation
  神戸市
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-19591843
[Presentation] Analysis of oncogenic activities of cyclin D1b variant in human bladder cancer cells2007
- Author(s)
  Kim CJ, Isono T, Tambe Y, Okada Y, Inoue H
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  横浜市
- Year and Date
  2007-10-05
- Data Source
  KAKENHI-PROJECT-19591843
[Presentation] Periostin activates TAK1 and suppresses cell invasiveness2007
- Author(s)
  Isono T, Kim CJ, Sakurai H, Okada Y, Inoue H
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  横浜市
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-19591843
[Presentation] Stress-inducible GADD34 interacts with TSC1/2 to suppress mTOR signaling pathway2007
- Author(s)
  Inoue H, Minami K, Tambe Y, Isono T, Chano T
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  横浜市
- Year and Date
  2007-10-05
- Data Source
  KAKENHI-PROJECT-19591843
[Presentation] Periostin activates TAK1 and suppresses cell invasiveness.2007
- Author(s)
  Isono T, Kim CJ, Sakurai H, Okada Y, Inoue H.
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  横浜市
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-19591843
[Presentation] Analysis of oncogellic activities of cyclin Dlb variant in human bladder cancer cells.2007
- Author(s)
  Kim CJ, Isono T, Tambe Y, Okada Y, Inoue H.
- Organizer
  第66回目本癌学会総会
- Place of Presentation
  横浜市
- Year and Date
  2007-10-05
- Data Source
  KAKENHI-PROJECT-19591843

1. CHANO Tokuhiro (40346028)

# of Collaborated Projects: 3 results

# of Collaborated Products: 12 results
2. YUASA Takeshi (00314162)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
3. INOUE Hirokazu (30176440)

# of Collaborated Projects: 2 results

# of Collaborated Products: 27 results
4. KAGEYAMA Susumu (50378452)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. YOSHIDA Tetsuya (60510310)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
6. KAWAUCHI Akihiro (90240952)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
7. KIM Chul Jang (10204968)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. OKAMOTO Keisei (50303780)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. OKABE Hidetoshi (70079713)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
10. WADA Atsuyuki (10273400)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
11. Yuichi Ishikawa (80222975)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. Yonese Junji (70469633)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. Kubota Shigehisa (80759118)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 尾松万里子 (80161397)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 松浦博 (60238962)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. SUZAKI Masafumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
17. KITA Hiroko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. KIMURA Fumiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. USHIO Akiyo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. ISHIDA Syouhei

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. MAKINO Ai

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. YAMAMOTO Takefumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. URUSHIYAMA Noboru

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. MORI Yasuhiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 金哲将

# of Collaborated Projects: 0 results

# of Collaborated Products: 19 results

Takahiro Isono 礒野 高敬

ISONO Takahiro 礒野 高敬

Research Projects

Research Products

Co-Researchers

Elucidation of the mechanism of antitumor effect in inhibition of GGCT expression using integrated omics analysis

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The exploratory research of biomarkers of renal cell carcinomas for therapeutic drugs based on the evidence of global transcriptome analysis.Principal Investigator

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Novel biomarker and therapeutic target in the targeted therapy for the patients with metastatic renal cell cancer

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Application of novel clinicopathological biomarkers to cancer treatment

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Analysis and clinical application of DNMT3L, a novel marker for human embryonal carcinoma

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Molecular mechanisms of the suppression of invasion and metastasis by periostin in urothelial carcinoma

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P2受容体刺激による前駆脂肪細胞の分化誘導因子に対する感受性増大機構の解明

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Review Section

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Analysis of the mechanism of suppression of invasiveness and metastasis by periostin gene in bladder cancerPrincipal Investigator

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Proteome analysis reveals molecular alternations of cardiac protein expression via Angiotensin-II in congestive heart failure

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[Journal Article] Hydroxyl-HIF2-alpha is potential therapeutic target for renal cell carcinomas.2016

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[Journal Article] Therapeutic inhibition of mitochondrial function induces cell death in starvation-resistant renal cell carcinomas.2016

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[Journal Article] Glucose deprivation induces G2/M transition-arrest and cell death in N-GlcNAc2-modified protein-producing renal carcinoma cells2014

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[Journal Article] Study of Global Transcriptional Changes of N-GlcNAc2 Proteins-Producing T24 Bladder Carcinoma Cells under Glucose Deprivation2013

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[Journal Article] Study of global transcriptional changes of N-GlcNAc2 proteins-producing T24 bladder carcinoma cells under glucose deprivation.2013

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Takahiro Isono 礒野高敬

ISONO Takahiro 礒野高敬