OHYASHIKI Junko 大屋敷純子

… Alternative Names

大屋敷純子オオヤシキジュンコ

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Researcher Number	20191950
External Links
Affiliation (based on the past Project Information) *help	2012 – 2018: 東京医科大学, 医学部, 教授 2007: Tokyo Medial University, School of Medicine, Clinical Research Associate 2007: Tokyo Medical University, School of Medicine, Associate Professor 2006: 東京医科大学, 医学部, 助教授 2005: 東京医科大学, 医学部, 講師 … More 1997: 東京医大, 医学部, 助手 1996: 東京医科大学, 医学部, 助手 1994: 東京医科大学, 内科第1講座, 助手 1992 – 1994: 東京医科大学, 医学部, 助手 1987 – 1990: 東京医科大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Hematology / Tumor therapeutics / Bioinformatics/Life informatics / Tumor diagnosis Except Principal Investigator Tumor diagnostics / Hematology
Keywords	Principal Investigator 造血器腫瘍 / 加齢 / miRNA / 腫瘍血管新生 / 多発性骨髄腫 / 骨髄間質細胞 / エクソソーム / logical operation / viral infection / absolute quantification … More / gene expression analysis / DNA computer / DNAマイクロアレイ / 論理演算 / ウイルス感染症 / 絶対定量 / 遺伝子発現解析 / DNAコンピューター / 5-azacytidine / telomere RNA / DNAメチル化 / 骨髄不全症候群 / 骨髄異形成症候群 / 5-アザシチジン / テロメアRNA / ゲノム不安定性 / テロメラーゼ / テロメア / マイクロサテライト / genonic instability / leukemia / wyelodysplastic syndrome / Telomere / RAG-1 / 脱メチル化 / T細胞受容体beta鎖遺伝子 / leukemia cells / gene rearrangewent / Methylotion / サイトカイン / 免疫関連遺伝子 / MーBCR / Ph陽性急性白血病 … More Except Principal Investigator 造血器腫瘍 / エクソソーム / 骨髄間質細胞 / 骨髄異形成症候群 / 細胞外小胞 / miRNA / cーmyb / 6qー / cーfms / 5qー / 対立遺伝子欠如 / BCRIABL / Ph陽性白血病 Less

Novel therapies development of multiple myeloma using engineering exosomes derived from bone marrow stromal cellsPrincipal Investigator
- Principal Investigator
  
  Ohyashiki Junko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Tokyo Medical University
Development of novel diagnostics for hematological malignancy on basis of the exosome analysis
- Principal Investigator
  
  Ohyashiki Kazuma
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor diagnostics
- Research Institution
  Tokyo Medical University
Telomere repeat-containing RNA (TERRA), a possible molecular marker of leukemiaPrincipal Investigator
- Principal Investigator
  
  OHYASHIKI Junko
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor diagnosis
- Research Institution
  Tokyo Medical University
Applications of molecular nanotechnology for human disease using DNA-encode based gene expression analysisPrincipal Investigator
- Principal Investigator
  
  OHYASHIKI Junko
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bioinformatics/Life informatics
- Research Institution
  Tokyo Medical University
造血器腫瘍におけるテロメラーゼの調節と分裂抑制遺伝子発現の分子レベルでの相互作用Principal Investigator
- Principal Investigator
  
  大屋敷純子
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Tokyo Medical University
造血器腫瘍におけるDNA修復機構とゲノム不安定性に関する研究Principal Investigator
- Principal Investigator
  
  大屋敷純子
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Tokyo Medical University
Ph'陽性急性白血病の生物学的意義とその集学的治療に関する研究
- Principal Investigator
  
  外山圭助
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Tokyo Medical University
骨髄異形成症候群の白血化過程におけるテロメア短縮様式とG2期制御機構Principal Investigator
- Principal Investigator
  
  大屋敷純子
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Tokyo Medical University
造血器腫瘍におけるゲノム構造の変化とリコンビナーゼ活性化遺伝子の相互作用Principal Investigator
- Principal Investigator
  
  大屋敷純子
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Tokyo Medical University
造血器腫瘍における遺伝子の脱メチル化状態に関する研究Principal Investigator
- Principal Investigator
  
  大屋敷純子
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Tokyo Medical University
Ph'陽性急性白血病における白血病細胞起源の解析および造血因子に対する反応の検討Principal Investigator
- Principal Investigator
  
  大屋敷純子
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Tokyo Medical University
パルスフィールド・ゲル電気泳動法による染色体脆弱部位の遺伝子解析Principal Investigator
- Principal Investigator
  
  大屋敷純子
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Hematology
- Research Institution
  Tokyo Medical University
ヒト白血病細胞におけるカルノア固定細胞を用いた遺伝子解析Principal Investigator
- Principal Investigator
  
  大屋敷純子
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Hematology
- Research Institution
  Tokyo Medical University
ヒト白血病細胞における対立遺伝子欠如に関する研究
- Principal Investigator
  
  外山圭助
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Tokyo Medical University
両表現型白血病細胞株におけるT細胞受体遺伝子の再編成とその発現に関する研究Principal Investigator
- Principal Investigator
  
  大屋敷純子
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Hematology
- Research Institution
  Tokyo Medical University

All 2019 2018 2017 2016 2015 2014 2013 2012 2007 2006 2005 Other

All Journal Article Presentation Book Patent

[Book] 貧血学―最新の診断・治療動向―：MDS診療ガイドラインにおける治療戦略・概論2017
- Author(s)
  大屋敷一馬
- Total Pages
  641
- Publisher
  日本臨牀社
- ISBN
- Data Source
  KAKENHI-PROJECT-15H04303
[Book] Chromosomes and chromosomal instability in human cancer. The Molecular Basis of Human Cancer (2nd Edition).2016
- Author(s)
  Ohyashiki K, Kuroda M, Ohyashiki JH
- Total Pages
  873
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-15H04303
[Book] 内科学第10版2015
- Author(s)
  大屋敷一馬
- Total Pages
  2548
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-15H04303
[Book] 入門腫瘍内科学（改訂第2版）2015
- Author(s)
  大屋敷一馬、大屋敷純子
- Total Pages
  234
- Publisher
  篠原出版
- Data Source
  KAKENHI-PROJECT-15H04303
[Journal Article] Maintenance 5-azacytidine therapy by MRD monitoring after allogeneic HSCT in myeloid/lymphoid neoplasms with FGFR1 rearrangement.2019
- Author(s)
  Katagiri S, Umezu T, Azuma K, Kobayashi C, Akahane D, Suguro T, Furuya N, Fujimoto H, Nakamura N, Ohyashiki JH, Ohyashiki K.
- Journal Title
  
  Bone Marrow Transplant.
  
  Volume: - Issue: 7 Pages: 1148-1150
- DOI
  10.1038/s41409-019-0436-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07244, KAKENHI-PROJECT-16K07183
[Journal Article] Exosomal miRNA Signatures for Late-Onset Acute Graft-Versus-Host Disease in Allogenic Hematopoietic Stem Cell Transplantation.2018
- Author(s)
  Yoshizawa S, Umezu T, Saitoh Y, Gotoh M, Akahane D, Kobayashi C, Ohyashiki JH, Ohyashiki K.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 19(9) Issue: 9 Pages: 2493-2493
- DOI
  10.3390/ijms19092493
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07244, KAKENHI-PROJECT-16K07183, KAKENHI-PROJECT-17K15656
[Journal Article] Extracellular vesicle (EV)- mediated cell-cell communication in hematologic neoplasms2018
- Author(s)
  Ohyashiki JH, Umezu T, Ohyashiki K
- Journal Title
  
  Philosophical Transactions of the Royal Society B: Biological Sciences
  
  Volume: 373 Issue: 1737 Pages: 1737-1737
- DOI
  10.1098/rstb.2016.0484
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04303, KAKENHI-PROJECT-15K06841, KAKENHI-PROJECT-18K07244, KAKENHI-PROJECT-16K07183
[Journal Article] Chromatin Regulation by HP1γ Contributes to Survival of 5-Azacytidine-Resistant Cells.2018
- Author(s)
  Imanishi S, Umezu T, Kobayashi C, Ohta T, Ohyashiki K, Ohyashiki JH.
- Journal Title
  
  Front Pharmacol.
  
  Volume: 9 Pages: 1166-1166
- DOI
  10.3389/fphar.2018.01166
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07244, KAKENHI-PROJECT-17H03585, KAKENHI-PROJECT-16K07183, KAKENHI-PROJECT-17K15656
[Journal Article] Genetic variations of bone marrow mesenchymal stromal cells derived from acute leukemia and myelodysplastic syndrome by targeted deep sequencing.2017
- Author(s)
  Azuma K, Umezu T, Imanishi S, Asano M, Yoshizawa S, Katagiri S, Ohyashiki K, Ohyashiki JH.
- Journal Title
  
  Leuk Res
  
  Volume: 62 Pages: 23-28
- DOI
  10.1016/j.leukres.2017.09.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07183, KAKENHI-PROJECT-15H04303, KAKENHI-PROJECT-15K06841
[Journal Article] Replenishing exosomes from older bone marrow stromal cells with miR-340 inhibits myeloma-related angiogenesis.2017
- Author(s)
  Umezu T, Imanishi S, Azuma K, Kobayashi C, Yoshizawa S, Ohyashiki K, Ohyashiki JH.
- Journal Title
  
  Blood Adv
  
  Volume: 1(13) Issue: 13 Pages: 812-823
- DOI
  10.1182/bloodadvances.2016003251
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07183, KAKENHI-PROJECT-17K15656, KAKENHI-PROJECT-15H04303, KAKENHI-PROJECT-15K06841
[Journal Article] Extracellular vesicle-mediated cell-cell communication in haematological neoplasms2017
- Author(s)
  Ohyashiki JH, Umezu T, Ohyashiki K.
- Journal Title
  
  Philosophical Transactions B of the Royal Society
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K07183
[Journal Article] Teriflunomide restores 5-azacytidine sensitivity via activation of pyrimidine salvage in 5-azacytidine-resistant leukemia cells.2017
- Author(s)
  Imanishi S, Takahashi R, Katagiri S, Kobayashi C, Umezu T, Ohyashiki K, Ohyashiki JH.
- Journal Title
  
  Oncotarget
  
  Volume: 8(41) Issue: 41 Pages: 69906-69915
- DOI
  10.18632/oncotarget.19436
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07183, KAKENHI-PROJECT-17K15656, KAKENHI-PROJECT-15H04303, KAKENHI-PROJECT-15K06841, KAKENHI-PROJECT-16K19186
[Journal Article] Hidden FLT3-D835Y clone in FLT3-ITD-positive acute myeloid leukemia that evolved into very late relapse with T-lymphoblastic leukemia2017
- Author(s)
  Katagiri S, Umezu T, Asano M, Akahane D, Azuma K, Makishima H, Yoshida K, Watatani Y, Chiba K, Miyano S, Ogawa S, Ohyashiki JH, Ohyashiki K
- Journal Title
  
  Leukemia and Lymphoma
  
  Volume: 3 Issue: 6 Pages: 1-4
- DOI
  10.1080/10428194.2017.1382696
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04303, KAKENHI-PROJECT-16H05338, KAKENHI-PROJECT-15K06841, KAKENHI-PROJECT-18K07244, KAKENHI-PLANNED-15H05909, KAKENHI-PROJECT-26221308, KAKENHI-PROJECT-16K07183
[Journal Article] Upregulated exosomal miRNA-140-3p in CML patients with musculoskeletal pain associated with discontinuation of tyrosine kinase inhibitors2017
- Author(s)
  Asano M, Umezu T, Katagiri S, Kobayashi C, Tauchi T, Gotoh M, Ando K, Okabe S, Ohyashiki JH, Ohyashiki K
- Journal Title
  
  Int J Hematol
  
  Volume: 105(4) Issue: 4 Pages: 419-422
- DOI
  10.1007/s12185-017-2199-z
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K06841, KAKENHI-PROJECT-16K07183, KAKENHI-PROJECT-17K15656, KAKENHI-PROJECT-15H04303
[Journal Article] Phase 1/2 study of the WT1 peptide cancer vaccine WT4869 in patients with myelodysplastic syndrome2017
- Author(s)
  Ueda Yasunori、Ogura Michinori、Miyakoshi Shigesaburo、Suzuki Takahiro、Heike Yuji、Tagashira Shuzo、Tsuchiya Satoru、Ohyashiki Kazuma、Miyazaki Yasushi
- Journal Title
  
  Cancer Science
  
  Volume: 108 Issue: 12 Pages: 2445-2453
- DOI
  10.1111/cas.13409
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09489, KAKENHI-PROJECT-15H04303
[Journal Article] Down-regulation of plasma miR-215 in chronic myeloid leukemia patients with successful imatinib discontinuation.2016
- Author(s)
  Ohyashiki K, Umezu T, Katagiri S, Kobayashi C, Azuma K, Tauchi T, Okabe S, Fukuoka Y, Ohyashiki JH
- Journal Title
  
  The International Journal of Molecular Sciences
  
  Volume: 17(4) Issue: 4 Pages: 570-570
- DOI
  10.3390/ijms17040570
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04303, KAKENHI-PROJECT-15K06841
[Journal Article] Exosomes promote bone marrow angiogenesis in hematologic neoplasia: the role of hypoxia.2016
- Author(s)
  Ohyashiki JH, Umezu T, Ohyashiki K
- Journal Title
  
  Curr Opin Hematol
  
  Volume: 23(3) Issue: 3 Pages: 268-273
- DOI
  10.1097/moh.0000000000000235
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06841, KAKENHI-PROJECT-15H04303, KAKENHI-PROJECT-16K07183
[Journal Article] Validation of cytogenetic risk groups according to International Prognostic Scoring Systems by peripheral blood CD34+ FISH: Results from a German diagnostic study in comparison with an international control group.2015
- Author(s)
  Braulke F, Ohyashiki K, et al
- Journal Title
  
  Haematologica
  
  Volume: 100(2) Issue: 2 Pages: 205-213
- DOI
  10.3324/haematol.2014.110452
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04303
[Journal Article] effect of deferasirox with 5-azacytidine in human leukemia cells in vitro.2015
- Author(s)
  Imanishi S, Takahashi R, Ohsuga M, Ohyashiki K, Ohyashiki JH
- Journal Title
  
  Annals of Hematology
  
  Volume: 94(9) Issue: 9 Pages: 1601-1602
- DOI
  10.1007/s00277-015-2417-9
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04303
[Journal Article] Frequency of del(12p) is commonly undetermined in myelodysplastic syndromes: Results from a German diagnostic study in comparison with an international control group.2015
- Author(s)
  Braulke F, Ohyashiki K, et al
- Journal Title
  
  Genes Chromosomes and Cancer
  
  Volume: 54(12) Issue: 12 Pages: 809-817
- DOI
  10.1002/gcc.22292
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04303
[Journal Article] 造血器腫瘍におけるエクソソームを介した細胞間相互作用機構：多発性骨髄腫を中心に2015
- Author(s)
  梅津知宏、大屋敷純子、大屋敷一馬
- Journal Title
  
  血液内科
  
  Volume: 71(3) Pages: 396-400
- Data Source
  KAKENHI-PROJECT-15H04303
[Journal Article] Downregulated microRNA-148b in circulating PBMCs in chronic myeloid leukemia patients with undetectable minimal residual disease: a possible biomarker to discontinue imatinib safely.2014
- Author(s)
  Ohyashiki JH, Ohtsuki K, Mizoguchi I, Yoshimoto T, Katagiri S, Umezu T, Ohyashiki K.
- Journal Title
  
  Drug Des Devel Ther.
  
  Volume: 8 Pages: 1151-1159
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24501344
[Journal Article] Constitutive activation of the ATM/BRCA1 pathway prevents DNA damage-induced apoptosis in 5-azacytidine-resistant cell lines.2014
- Author(s)
  Imanishi S, Umezu T, Ohtsuki K, Kobayashi C, Ohyashiki K, Ohyashiki JH.
- Journal Title
  
  Biochem Pharmacol.
  
  Volume: 89 Issue: 3 Pages: 361-369
- DOI
  10.1016/j.bcp.2014.03.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24501344
[Journal Article] Exosomes derived from hypoxic leukemia cells enhance tube formation in endothelial cells.2013
- Author(s)
  Tadokoro H, Umezu T, Ohyashiki K, Hirano T, and Ohyashiki JH.
- Journal Title
  
  J. Biol. Chem
  
  Volume: 288 Issue: 48 Pages: 34343-34351
- DOI
  10.1074/jbc.m113.480822
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24501344, KAKENHI-PROJECT-25830089
[Journal Article] An association between ApoE 4/4 phenotype and telomere erosion in Alzheimer’s disease.2012
- Author(s)
  Takata Y, Kikukawa M, Hanyu H, Koyama S, Shimizu S, Umahara T, Sakurai H, Iwamoto T, Ohyashiki K, Ohyashiki JH.
- Journal Title
  
  J Gerontol A Biol Sci Med Sci.
  
  Volume: 67 Pages: 330-335
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24501344
[Journal Article] Telomere length shortening in patients with dementia with Lewy bodies.2012
- Author(s)
  Kume K, Kikukawa M, Hanyu H, Takata Y, Umahara T, Sakurai H, Kanetaka H, Ohyashiki K, Ohyashiki JH,
- Journal Title
  
  Eur J Neurol.
  
  Volume: 19 Pages: 905-910
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24501344
[Journal Article] Induction of heme oxygenase-1 by cobalt protoporphyrin enhances the antitumour effect of bortezomib in adult T-cell leukaemia cells2007
- Author(s)
  Hamamura, RS., Ohyashiki, JH., Kurashina, R., Kobayashi, C., Zhang, Y., Takaku, T., Ohyashiki, K
- Journal Title
  
  Br J Cancer 97(8)
  
  Pages: 1099-105
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17300095
[Journal Article] JAK2(V617F) mutational status as determined by semiquantitative sequence-specific primer-single molecule fluorescence detection assay is linked to clinical features in chronic myeloproliferative disorders.2007
- Author(s)
  Ohyashiki K. et al.
- Journal Title
  
  Leukemia (In press)
- Data Source
  KAKENHI-PROJECT-17300095
[Journal Article] Transcriptional profiling of Epstein-Barr virus(EBV) genes and host cellular genes in nasal NK/T-cell lymphoma and chronic active EBV infection2006
- Author(s)
  Zhang, Y., Ohyashiki, JH., Takaku, T., Shimizu, N., Ohyashiki, K
- Journal Title
  
  Br J Cancer 94(4)
  
  Pages: 599-608
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17300095
[Journal Article] Estimating immunoregulatory gene networks in human herpesvirus type 6-infected T cells2005
- Author(s)
  Takaku, T., Ohyashiki, JH., Zhang, Y., Ohyashiki, K
- Journal Title
  
  Biochem Biophys Res Commun 336(2)
  
  Pages: 469-77
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17300095
[Patent] がんの罹患の可能性の試験方法およびそれに用いる試験試薬2017
- Inventor(s)
  大屋敷純子、梅津知宏
- Industrial Property Rights Holder
  学校法人東京医科大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-083898
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-16K07183
[Presentation] Characterization of novel bona marrow stromal cells from healthy donors.2018
- Author(s)
  Umezu T, Gladkova N, Imanishi S, Ohyashiki K, Ohyashiki JH
- Organizer
  第36回ヒト細胞学会学術集会
- Data Source
  KAKENHI-PROJECT-16K07183
[Presentation] Extracellular vesicle-mediated miRNA transfer enhances growth and survival of multiple myeloma.2018
- Author(s)
  Umezu T, Imanishi, Yoshizawa S, Ohyashiki K, Ohyashiki JH
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K07183
[Presentation] 5-azacytidine targets chromatin regulation through piRNA pathway.2018
- Author(s)
  Imanishi S, Azuma K, Umezu T, Kawana C, Ohyashiki K, Ohyashiki JH
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K07183
[Presentation] The role of extracellular vesicle-mediated miR-10a transfer in bone marrow microenvironment of patients with multiple myeloma.2018
- Author(s)
  Umezu T, Ohyashiki K, Ohyashiki JH
- Organizer
  International Society for Extracellular Vesicles 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07183
[Presentation] Bone marrow mesenchymal stromal cells from healthy donors secrete anti-angiogenic EVs as well as soluble factors having growth inhibitory effect in MM.2018
- Author(s)
  Umezu T, Imanishi S, Gladkova N*, Ohyashiki K, Ohyashiki JH
- Organizer
  European Hematology Association 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07183
[Presentation] Sequential analysis of clonal evolution by targeted deep sequencing in therapy-related myeloid neoplasm.2018
- Author(s)
  Katagiri S, Azuma K, Saito Y, Yoshizawa S, Akahane D, Fujimoto H, Ito Y, Umezu T, Ohyashiki JH, Ohyashiki K
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-16K07183
[Presentation] Teriflunomide restores 5-azacytidine sensitivity via activation of pyrimidine salvage in 5-azacytidine-resistant leukemia cells2017
- Author(s)
  Imanishi S, Takahashi R, Katagiri S, Umezu T, Kobayashi C, Ohyashiki K, Ohyashiki JH
- Organizer
  The 14th International Symposium on Myelodysplastic Syndromes
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04303
[Presentation] Extracellular vesicles (EVs) released by bone marrow stromal cells show a distinct miRNA profile in high-risk MDS patients.2017
- Author(s)
  Ohyashiki K, Saitoh Y, Imanishi S, Umezu T, Yoshizawa S, Asano M, Fujimoto H, Akahane D, Kobayashi C, Ohyashiki JH:
- Organizer
  The 14th International Symposium on Myelodysplastic Syndromes (MDS2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07183
[Presentation] RUNX2 super enhancer promotes the development of blastic plasmacytoid dendritic cell neoplasm. 21th RUNX meeting2017
- Author(s)
  Sashida G, Kubota S, Tokunaga K, Oshima M, Umezu T, Kanai A, Tan KT, Yang H, Iwanaga E, Asou N, Maeda T, Iwama A, Ohyashiki K, Osato M
- Organizer
  21th RUNX meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04303
[Presentation] Inhibition of extracellular vesicle secretion induces apoptosis of bone marrow stromal cells: Towards soil-targeted therapy in multiple myeloma.2017
- Author(s)
  Umezu T, Imanishi S, Yoshizawa S, Ohyahsiki K, Ohyashiki JH
- Organizer
  22nd Congress of European Hematology Association (EHA2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07183
[Presentation] Molecular signatures that predict response to azacitidine treatment for myelodysplastic syndromes2017
- Author(s)
  Nannya Y, Takeda J, Sato S, Shiozawa Y, Shiraishi Y, Kataoka K, Chiba K, Tanaka H, Chiba S, Asou N, Kiyoi H, Imai K, Hirase C, Dobashi N, Kiguchi T, Nakao S, Ohyashiki K, Miyazaki Y, Naoe T, Makishima H, Miyano S, Kenichi Yoshida K, Ogawa S*
- Organizer
  59th ASH annual meeting and exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04303
[Presentation] Replenishing exosomes from older bone marrow stromal cells by miR-340 inhibits myeloma-related angiogenesis.2017
- Author(s)
  Umezu T, Imanishi S, Azuma K, Yoshizawa S, Ohyashiki K, Ohyashiki JH:
- Organizer
  The Royal Society Scientific Meeting 2017 “Extracellular vesicles and the tumor microenvironment”
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07183
[Presentation] Inhibition of extracellular vesicle secretion induces apoptosis of bone marrow stromal cells derived from multiple myeloma patients.2017
- Author(s)
  Umezu T, Imanishi S, Azuma K, Yoshizawa S, Ohyashiki K, Ohyashiki JH
- Organizer
  The 76th Annual Meeting of Japanese Cancer Association (JCA2017)
- Data Source
  KAKENHI-PROJECT-16K07183
[Presentation] Inhibition of extracellular vesicle secretion induces apoptosis of bone marrow stromal cells: Towards soil-targeted therapy in multiple myeloma2017
- Author(s)
  Umezu T, Imanishi S, Yoshizawa S, Ohyashiki K, Ohyashiki JH
- Organizer
  22th European Hematology Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04303
[Presentation] Role of extracellular vesicles-mediated angiogensis in hematologic neoplasias2017
- Author(s)
  Ohyashiki JH
- Organizer
  Royal Society meeting entitled ‘Extracellular Vesicles in the Tumor Microenvironment’
- Place of Presentation
  London (UK)
- Year and Date
  2017-01-23
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07183
[Presentation] Extracellular vesicles (EVs) released by bone marrow stromal cells show a distinct miRNA profiling in high-risk MDS patients2017
- Author(s)
  Ohyashiki K, Saitoh Y, Imanishi S, Umezu T, Yoshizawa S, Asano M, Fujimoto H, Akahane D, Kobayashi C, Ohyashiki JH
- Organizer
  The 14th International Symposium on Myelodysplastic Syndromes
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04303
[Presentation] A role of exosomal miR-10a in bone marrow stromal cells obtained from patients with multiple myeloma.2017
- Author(s)
  Umezu T, Imanishi S, Yoshizawa S, Ohyashiki K, Ohyashiki JH
- Organizer
  6th Annual Meeting of International Society for Extracellular Vesicles (ISEV2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07183
[Presentation] Cross-talk mediated by bone marrow stromal cells-derived extracellular vesicles.2017
- Author(s)
  Umezu T, Imanishi S, Yoshizawa S, Ohyashiki K, Ohyashiki JH
- Organizer
  Tokyo Medical University, Institute of Medical Science, 1st International Symposium “Role of Aging and Cancer”
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07183
[Presentation] Teriflunomide restores 5-azacytidine sensitivity via activation of pyrimidine salvage in 5-azacytidine-resistant leukemia cells.2017
- Author(s)
  Imanishi S, Takahashi R, Katagiri S, Umezu T, Yoshizawa S, Kobayashi C, Ohyashiki K, Ohyashiki JH:
- Organizer
  The 14th International Symposium on Myelodysplastic Syndromes (MDS2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07183
[Presentation] Combining effects of the SMO inhibitor and BCL-2 inhibitor in MDS-derived induced potent stem cells (iPS)2017
- Author(s)
  Tauchi T, Okabe S, Katagiri S, Tanaka Y, Ohyashiki K
- Organizer
  59th ASH annual meeting and exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04303
[Presentation] Telomeric repeat-containing RNA (TERRA) in MDS: Utility of cell-free TERRA packaged in extracellular vesicles.2017
- Author(s)
  Ohyashiki JH, Umezu T, Kobayashi C, Imanishi S, Asano M, Ohyashiki K:
- Organizer
  The 14th International Symposium on Myelodysplastic Syndromes (MDS2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07183
[Presentation] Combining effects of the SMO inhibitor and JAK1 inhibitor in MDS-derived induced potent stem cells (iPS)2017
- Author(s)
  Tauchi T, Okabe S, Katagiri S, Tanaka Y, Ohyashiki K
- Organizer
  22th European Hematology Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04303
[Presentation] Altered exosomal miRNA expression of late onset acute graft-versus-host disease in allogenic hematopoietic stem cell transplantation.2017
- Author(s)
  Yoshizawa S, Umezu T, Saitoh Y, Gotoh M, Akahane D, Kobayashi C, Ohyashiki JH, Ohyashiki K
- Organizer
  The 79th Annual Meeting of Japanese Society of Hematology (JSH2017)
- Data Source
  KAKENHI-PROJECT-16K07183
[Presentation] miRNA profiling of circulating extracellular vesicles in CML patients with musculoskeletal pain associated with discontinuation of tyrosine kinase inhibitors.2017
- Author(s)
  Ohyashiki K, Asano M, Umezu T, Katagiri S, Kobayashi C, Tauchi T, Gotoh M, Ando K, Okabe S, Ohyashiki JH:
- Organizer
  22nd Congress of European Hematology Association (EHA2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07183
[Presentation] miRMA profiling of circulating extracellular vesicles in CML patients with musculoskeletal pain associated with discontinuation of tyrosine kinase inhibitors2017
- Author(s)
  Ohyashiki K, Asano M, Umezu T, Katagiri S, Kobayashi C, Tauchi T, Gotoh M, Ando K, Okabe S, Ohyashiki K
- Organizer
  22th European Hematology Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04303
[Presentation] Inhibition of extracellular vesicle secretion induces apoptosis of bone marrow stroma cells2017
- Author(s)
  Umezu T, Imanishi S, Yoshizawa Sm Ohyashiki K, Ohyashiki JH
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15H04303
[Presentation] 慢性骨髄性白血病におけるチロシンキナーゼ阻害薬中止後の筋骨格痛ではエクソソームmiR-140-3pの上昇がみられる2016
- Author(s)
  浅野倫代、梅津知宏、片桐誠一朗、小林千晶、田内哲三、岡部聖一、大屋敷純子、大屋敷一馬
- Organizer
  第178回東京医科大学医学会総会
- Place of Presentation
  東京
- Year and Date
  2016-11-05
- Data Source
  KAKENHI-PROJECT-15H04303
[Presentation] Clonal evolution in AML which relapsed 15 years after BMT2016
- Author(s)
  Katagiri S, Azuma K, Umezu T, Akahane D, Wataya Y, Yoshida K, Makishima H, Ogawa S, Ohyashiki JH, Ohyashiki K
- Organizer
  第78回日本血液学会総会
- Place of Presentation
  横浜
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-15H04303
[Presentation] アザシチジン耐性白血病細胞におけるヒストン化学修飾の役割の解明2016
- Author(s)
  髙橋諒子、今西哲、梅津知宏、小林千晶、大屋敷一馬、大屋敷純子
- Organizer
  第178回東京医科大学医学会総会
- Place of Presentation
  東京
- Year and Date
  2016-11-05
- Data Source
  KAKENHI-PROJECT-15H04303
[Presentation] Toward exosome-based cancer therapy: rejuvenation of exosomes derived from normal bone stroma cells2016
- Author(s)
  Umezu T, Imanishi S, Azuma K, Kobayashi C, Ohyashiki K, Ohyashiki JH
- Organizer
  ISEV 2016
- Place of Presentation
  Rotterdam
- Year and Date
  2016-05-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04303
[Presentation] Mutation analysis of bone marrow stromal cells derived from AML and MDS2016
- Author(s)
  Azuma K, Umezu T, Imanishi S, Asano M, Yoshizawa S, Katagiri S, Ohyashiki K, Ohyashiki JH
- Organizer
  第78回日本血液学会総会
- Place of Presentation
  横浜
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-15H04303
[Presentation] Bone marrow stromal cells from young healthy donors secrete exosomes that inhibit in vivo angiogenesis in multiple myeloma.2016
- Author(s)
  Umezu T, Imanishi S, Azuma K, Kobayashi C, Ohyashiki K, Ohyashiki JH
- Organizer
  10th AACR-JCA Joint Conference
- Place of Presentation
  Maui, Hawaii
- Year and Date
  2016-02-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04303
[Presentation] 骨髄間質細胞が放出するエクソソーム内加齢関連miRNAの同定と機能解析2016
- Author(s)
  関野知聖、梅津知宏、吉澤成一郎、大屋敷一馬、大屋敷純子
- Organizer
  第178回東京医科大学医学会総会
- Place of Presentation
  東京
- Year and Date
  2016-11-05
- Data Source
  KAKENHI-PROJECT-15H04303
[Presentation] Clinical relevance of plasma miR-215 level in CML patients treated with imatinib2016
- Author(s)
  Katagiri S, Umezu T, Kobayashi C, Azuma K, Tauchi T, Okabe S, Ohyashiki JH, Ohyashiki K
- Organizer
  7th JSH International Symposium
- Place of Presentation
  Awajishima
- Year and Date
  2016-05-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04303
[Presentation] Down-regulation of plasma miR-215 in chronic myeloid leukemia patients with successful imatinib discontinuation.2016
- Author(s)
  Ohyashiki K, Umezu T, Katagiri S, Kobayashi C, Azuma K, Tauchi T, Okabe S, Fukuoka Y, Ohyashiki JH
- Organizer
  10th AACR-JCA Joint Conference
- Place of Presentation
  Maui, Hawaii
- Year and Date
  2016-02-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04303
[Presentation] Anti-angiogenic effect of normal bone marrow stromal cell-derived exosomes rejuvenated by miR-340.2016
- Author(s)
  Umezu T, Imanishi S, Azuma K, Yoshizawa S, Ohyashiki K, Ohyashiki JH
- Organizer
  The 78th Annual Meeting of Japanese Society of Hematology
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-16K07183
[Presentation] The genome-wide DNA methylation status as a predictor of 5-azacytidine in clinical responses.2015
- Author(s)
  Asao M, Kobayashi C, Umezu T, Ohyashiki K, Ohyashiki K
- Organizer
  6th JSH International symposium
- Place of Presentation
  軽井沢
- Year and Date
  2015-05-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04303
[Presentation] Exosomal miRNA signature of bone marrow mesenchymal stromal cells derived from MDS patients.2015
- Author(s)
  Saitoh Y, Imanishi S, Umezu T, Yoshizawa S, Asano M, Fujimoto H, Akahane D, Yamamoto Y, Kobayashi C, Ohyashiki JH, Ohyashiki K
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  金沢
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-15H04303
[Presentation] Exosomal miRNA signature of late onset acute GVHD in allogeneic HSCT.2015
- Author(s)
  Yoshizawa S, Umezu T, Ohyashiki JH, Ohyashiki K
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  金沢
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-15H04303
[Presentation] Exosome-based therapeutic approach using exosomal miRNAs derived from bone marrow mesenchymal stromal cells.2015
- Author(s)
  Umezu T, Imanishi S, Azuma K, Yoshizawa S, Ohyashiki K, Ohyashiki JH
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15H04303
[Presentation] A Phase 1/2 study of WT1 peptide cancer vaccine WT4869 in patients with myelodysplastic syndromes (MDS).2015
- Author(s)
  Suzuki T, Ohyashiki K
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  金沢
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-15H04303
[Presentation] Distinct exosomal miRNA expression of late onset graft-versus-host disease in allogeneic hematopoietic stem cell transplantation.2015
- Author(s)
  Yoshizawa S, Umezu T, Ohyashiki JH, Ohyashiki K
- Organizer
  20th European Hematology Association Congress
- Place of Presentation
  Wien, Austria
- Year and Date
  2015-06-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04303
[Presentation] Telomere repeat-containing RNA (TERRA), a possible epigenetic biomarker of DNA damage phenotype in 5-azacytidine-resistant leukemia cells2015
- Author(s)
  Kenko Azuma, Tomohiro Umezu, Satoshi Imanishi, Chiaki Kobayashi, Michiyo Asano, Seiichiro Katagiri, Daigo Akahane, Kazuma Ohyashiki, Junko H. Ohyashiki
- Organizer
  The 6th JSH International Symposium
- Place of Presentation
  軽井沢
- Year and Date
  2015-05-22
- Data Source
  KAKENHI-PROJECT-24501344
[Presentation] Bone marrow mesenchymal stromal cells from healthy donors secrete exosomes that inhit in vivo tumor growth and angiogenesis in multiple myeloma.2015
- Author(s)
  Umezu T, Ohyashiki K, Ohyashiki JH
- Organizer
  20th European Hematology Association Congress
- Place of Presentation
  Wien, Austria
- Year and Date
  2015-06-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04303
[Presentation] Age-related alterations in exosomal miRNAs derived from bone marrow mesenchymal stromal cells.2015
- Author(s)
  Umezu T, Ohyashiki K, Ohyashiki JH
- Organizer
  6th JSH International symposium
- Place of Presentation
  軽井沢
- Year and Date
  2015-05-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04303
[Presentation] Towards comprehensive understanding of the mechanism underlying resistance to 5-azacytidine2014
- Author(s)
  Imanishi S, Umezu T, Ohtsuki K, Kobayshi C, Ohyashiki K, Ohyashiki JH.
- Organizer
  5th JSH International Symposium, 2014
- Place of Presentation
  アクトシティ浜松、浜松、静岡
- Year and Date
  2014-05-24
- Data Source
  KAKENHI-PROJECT-24501344
[Presentation] A possible role of DNA damage/repair in 5-azacytidine resistant leukemia cells.2013
- Author(s)
  Imanishi S, Umezu T, Ohtsuki K, Kobayashi C, Ohyashiki K, Ohyashiki JH
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24501344
[Presentation] A possible association between 5-azacytidine sensitivity and epigenetic modulation of telomere in human leukemia cells.2013
- Author(s)
  Ohyashiki JH, Umezu T, Kobayashi C, Imanishi S, Asano M, Ohyashiki K
- Organizer
  12th International Symposium on MDS syndrome
- Place of Presentation
  Berlin, Germany
- Data Source
  KAKENHI-PROJECT-24501344
[Presentation] DNA methylated index of peripheral blood is a predictive marker for resistance to azacytidine in MDS patients. 12th International Symposium on MDS syndrome2013
- Author(s)
  Asano M, Ohyashiki JH, Umezu T, Kobayashi C, Fujimoto H, Gotoh M, Alahane D, Kitahara T, Yoshizawa S, Ito Y, Ohyashiki K.
- Organizer
  12th International Symposium on MDS syndrome
- Place of Presentation
  Berlin, Germany
- Data Source
  KAKENHI-PROJECT-24501344
[Presentation] Involvement of pyrimidine metabolism pathway in 5’-azacytidine resistance.2013
- Author(s)
  Imanishi S, Umezu T, Kobayashi C, Ohyashiki K, Ohyashiki JH
- Organizer
  AACR Annual Meeting 2013
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-24501344
[Presentation] DNA demethylation and up-regulation of telomere repeat-containing RNAs (TERRAs) in human leukemia cells.2012
- Author(s)
  大屋敷純子、梅津知宏、小林千晶、大屋敷一馬
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24501344
[Presentation] A net work approach to anti-cancer effect of bortezomib in adult T-cell leukemia cell2007
- Author(s)
  Ohyashiki JH
- Organizer
  第65回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-09-29
- Data Source
  KAKENHI-PROJECT-17300095
[Presentation] DNAコンピューターによる演算を応用した遺伝子発現解析:診断デバイスとしての意義2006
- Author(s)
  大屋敷純子
- Organizer
  日本入類遺伝学会第51回大会
- Place of Presentation
  米子,鳥取
- Year and Date
  2006-10-20
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17300095
[Presentation] A novel Quanta-DNA Chip for gene expression analysis : DNA computing using the DNA Coded Number(DCN) methods2005
- Author(s)
  Ohyashiki, JH., Nakajima, T., Makino, T., Takaku, T., Ohyashiki, K., Suyama, A
- Organizer
  96th Annual Meeting forAmerican Association for Cancer Research, April
- Place of Presentation
  Anaheim, USA
- Year and Date
  2005-04-15
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17300095
[Presentation] テロメアRNA (TelRNA)を指標とした５―アザシチジン有効性の予測
- Author(s)
  大屋敷純子、梅津知宏、今西　哲、東　剣虹、小林千晶、大屋敷一馬
- Organizer
  第59回日本人類遺伝学会・第21回日本遺伝子診療学会合同大会
- Place of Presentation
  タワーホール船堀、船堀、東京
- Year and Date
  2014-11-20 – 2014-11-22
- Data Source
  KAKENHI-PROJECT-24501344

1. Ohyashiki Kazuma (20201387)

# of Collaborated Projects: 4 results

# of Collaborated Products: 37 results
2. UMEZU Tomohiro (40385547)

# of Collaborated Projects: 3 results

# of Collaborated Products: 63 results
3. 外山圭助 (00051293)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. YAMADA Seiko (30408257)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 宮澤啓介 (50209897)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 高久智生 (20408256)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
7. 鈴木隆浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

OHYASHIKI Junko 大屋敷 純子

大屋敷 純子 オオヤシキ ジュンコ

Research Projects

Research Products

Co-Researchers

Novel therapies development of multiple myeloma using engineering exosomes derived from bone marrow stromal cellsPrincipal Investigator

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Development of novel diagnostics for hematological malignancy on basis of the exosome analysis

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Telomere repeat-containing RNA (TERRA), a possible molecular marker of leukemiaPrincipal Investigator

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Applications of molecular nanotechnology for human disease using DNA-encode based gene expression analysisPrincipal Investigator

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造血器腫瘍におけるテロメラーゼの調節と分裂抑制遺伝子発現の分子レベルでの相互作用Principal Investigator

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造血器腫瘍におけるDNA修復機構とゲノム不安定性に関する研究Principal Investigator

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Ph'陽性急性白血病の生物学的意義とその集学的治療に関する研究

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骨髄異形成症候群の白血化過程におけるテロメア短縮様式とG2期制御機構Principal Investigator

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造血器腫瘍におけるゲノム構造の変化とリコンビナーゼ活性化遺伝子の相互作用Principal Investigator

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造血器腫瘍における遺伝子の脱メチル化状態に関する研究Principal Investigator

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Ph'陽性急性白血病における白血病細胞起源の解析および造血因子に対する反応の検討Principal Investigator

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パルスフィールド・ゲル電気泳動法による染色体脆弱部位の遺伝子解析Principal Investigator

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ヒト白血病細胞におけるカルノア固定細胞を用いた遺伝子解析Principal Investigator

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OHYASHIKI Junko 大屋敷純子

大屋敷純子オオヤシキジュンコ