Shibayama Naoya 柴山修哉

… Alternative Names

柴山修哉シバヤマナオヤ

SHIBAYAMA Naoya 柴山修哉

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Researcher Number	20196439
Other IDs
Affiliation (Current)	2025: 自治医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2015 – 2023: 自治医科大学, 医学部, 教授 2012 – 2013: 自治医科大学, 医学部, 教授 2011: 自治医科大学, 医学部, 講師 2005 – 2009: 自治医科大学, 医学部, 講師 1998 – 2002: 自治医科大学, 医学部, 講師 … More 1996: 自治医科大学, 医学部, 講師 1992 – 1994: 自治医科大学, 医学部, 講師 1990 – 1991: 自治医科大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Biophysics / Biophysics / Basic Section 43040:Biophysics-related / Complex systems Except Principal Investigator Medium-sized Section 28:Nano/micro science and related fields / Science and Engineering
Keywords	Principal Investigator ヘモグロビン / アロステリー / X線結晶構造解析 / 2状態モデル / 酸素平衡曲線 / ゾル・ゲル法 / ダイナミクス / ゾル・ゲル / 多孔性ゲル / 多孔性ガラス … More / 構造機能相関 / 酸素平衡機能 / 多孔性シリカゲル / 結晶構造 / アロステリックモデル / 結晶構造解析 / MWCモデル / 酸素親和性 / 光解離法 / 光解離 / 動的構造解析 / タンパク質構造変化 / β-lactoglobulin / ubiquitin / cytochrome c / biophysics / sol-gel / folding / protein / β-ラクトグロプリン / β-ラクトグロブリン / ユビキチン / シトクロムc / 生物物理学 / 折れたたみ / タンパク質 / Ｘ線結晶構造解析 / ２状態モデル / 休眠打破 / タイマータンパク質 / 生物時計 / タンパク質のフォールディング / フォールディング / シトクロムC / ミオグロビン / 構造固定 / バクテリオロドプシン / X線結晶解析 / 酸素平衝曲線 / アロステリック効果 … More Except Principal Investigator 金属タンパク質 / 急速凍結法 / X線吸収スペクトル / X線 / 反応中間体 / EXAFS / マイクロ秒高速1分子 / 分子内部動態 / レーザー励起 / X線1分子動態 / 光励起１分子計測 / レーザー励起動態 / 1分子内部動態計測 / １分子計測 / ヘモグロビン / X線１分子追跡法 / 光励起 / タンパク質1分子動態 / へモグロビン / アロステリック効果 / 1分子 / 中性子 / バイオ計測 / Ｘ線１分子追跡法 / 蛋白質構造動態 / 新規計測手段 / 1分子動態情報 / 局部構造 / バイオテクノロジー / Ｘ線1分子追跡法 / 3次元分子内部動態情報 / Ｘ線1分子計測 / 価数変化 / 蛍光Ｘ線ホログラフィー / 結晶化 / タンパク質分子 / 標識・無標識法 / X線1分子追跡法 / 蛍光X線ホログラフィー / カルボキシペプチダーゼA / 配位構造 / 分散型EXAFS Less

Determination of single hemoglobin dynamics with x-rays
- Principal Investigator
  
  SASAKI YUJI
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 28:Nano/micro science and related fields
- Research Institution
  The University of Tokyo
Semi-comprehensive functional determination of crystal structures of hemoglobinPrincipal Investigator
- Principal Investigator
  
  Shibayama Naoya
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43040:Biophysics-related
- Research Institution
  Jichi Medical University
Direct observation of ligand and protein dynamics within hemoglobin at workPrincipal Investigator
- Principal Investigator
  
  Shibayama Naoya
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biophysics
- Research Institution
  Jichi Medical University
ヘモグロビンの四次構造変化を許容する結晶を用いた時分割構造解析法の開拓Principal Investigator
- Principal Investigator
  
  柴山修哉
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Jichi Medical University
3D Active Site Science in Biology
- Principal Investigator
  
  Sasaki Yuji
- Project Period (FY)
  2014 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  The University of Tokyo
Elucidation of the true picture of the hemoglobin allosteric equilibriumPrincipal Investigator
- Principal Investigator
  
  SHIBAYAMA Naoya
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biophysics
- Research Institution
  Jichi Medical University
タイマータンパク質EA4の計時機構解明を目指した研究Principal Investigator
- Principal Investigator
  
  柴山修哉
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biophysics
- Research Institution
  Jichi Medical University
Slow motion analysis of the fokling reactions of proteins within wet silica gelsPrincipal Investigator
- Principal Investigator
  
  SHIBAYAMA Naoya
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biophysics
- Research Institution
  Jichi Medical University
ゾル・ゲル包括法によるタンパク質分子の構造・機能解析Principal Investigator
- Principal Investigator
  
  柴山修哉
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Biophysics
- Research Institution
  Jichi Medical University
多孔性ゲルによるタンパク質の微視的構造状態の機能解析Principal Investigator
- Principal Investigator
  
  柴山修哉
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biophysics
- Research Institution
  Jichi Medical University
多孔性ガラスによるタンパク質の高次構造固定法を用いたタンパク質機能の研究Principal Investigator
- Principal Investigator
  
  柴山修哉
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biophysics
- Research Institution
  Jichi Medical University
多孔性ガラスによるタンパク質の高次構造固定法の開発と2状態モデルの直接的検証Principal Investigator
- Principal Investigator
  
  柴山修哉
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biophysics
- Research Institution
  Jichi Medical University
架橋混成ヘモグロビンを用いたアロステリック効果の研究Principal Investigator
- Principal Investigator
  
  柴山修哉
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biophysics
- Research Institution
  Jichi Medical University
急速凍結X線吸の収スペクトル法による錯体、金属タンパク質の反応過程の解析
- Principal Investigator
  
  西郷敏
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Jichi Medical University
X線吸収スペクトルの時間分解測定による錯体,金属タンパク質の反応過程の解析
- Principal Investigator
  
  西郷敏
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Jichi Medical University
分散型EXAFS法の高感度化とそれによる錯体,金属酵素の反応の動的解析
- Principal Investigator
  
  西郷敏
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Jichi Medical University

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All Journal Article Presentation

[Journal Article] いまさらヘモグロビン？ヘモグロビンのアロステリーを再考する2023
- Author(s)
  柴山　修哉
- Journal Title
  
  人工血液
  
  Volume: 31 Pages: 43-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06601
[Journal Article] Heme-bound tyrosine vibrations in hemoglobin M: Resonance Raman, crystallography, and DFT calculation2022
- Author(s)
  Nagatomo Shigenori、Shoji Mitsuo、Terada Takuto、Nakatani Kiyoharu、Shigeta Yasuteru、Hirota Shun、Yanagisawa Sachiko、Kubo Minoru、Kitagawa Teizo、Nagai Masako、Ohki Mio、Park Sam-Yong、Shibayama Naoya
- Journal Title
  
  Biophysical Journal
  
  Volume: 121 Issue: 14 Pages: 2767-2780
- DOI
  10.1016/j.bpj.2022.06.012
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06601, KAKENHI-PROJECT-20K03877, KAKENHI-PROJECT-20H00324, KAKENHI-PLANNED-19H05784, KAKENHI-PLANNED-20H05453, KAKENHI-PUBLICLY-22H04800
[Journal Article] X-ray fluorescence holography of biological metal sites: Application to myoglobin2022
- Author(s)
  Sato-Tomita Ayana、Ang Artoni Kevin R.、Kimura Koji、Marumi Riho、Happo Naohisa、Matsushita Tomohiro、Park Sam-Yong、Shibayama Naoya、Sasaki Yuji C.、Hayashi Kouichi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 635 Pages: 277-282
- DOI
  10.1016/j.bbrc.2022.10.003
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06601, KAKENHI-PLANNED-20H05881, KAKENHI-PLANNED-20H05884, KAKENHI-ORGANIZER-20H05878
[Journal Article] Freezable and Unfreezable Hydration Water: Distinct Contributions to Protein Dynamics Revealed by Neutron Scattering2021
- Author(s)
  Yamamoto Naoki、Kofu Maiko、Nakajima Kenji、Nakagawa Hiroshi、Shibayama Naoya
- Journal Title
  
  The Journal of Physical Chemistry Letters
  
  Volume: 12 Issue: 8 Pages: 2172-2176
- DOI
  10.1021/acs.jpclett.0c03786
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06601, KAKENHI-PROJECT-20H02944, KAKENHI-PROJECT-18K03559
[Journal Article] Pumping mechanism of NM-R3, a light-driven bacterial chloride importer in the rhodopsin family2020
- Author(s)
  Yun Ji-Hye、Ohki Mio、Park Jae-Hyun、Ishimoto Naito、Sato-Tomita Ayana、Lee Wonbin、Jin Zeyu、Tame Jeremy R. H.、Shibayama Naoya、Park Sam-Yong、Lee Weontae
- Journal Title
  
  Science Advances
  
  Volume: 6 Issue: 6 Pages: 6-6
- DOI
  10.1126/sciadv.aay2042
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06601, KAKENHI-WRAPUP-19H05451, KAKENHI-PROJECT-16K07326, KAKENHI-PLANNED-19H05779, KAKENHI-PROJECT-18H02413
[Journal Article] Allosteric transitions in hemoglobin revisited2020
- Author(s)
  Shibayama Naoya
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - General Subjects
  
  Volume: 1864 Issue: 2 Pages: 129335-129335
- DOI
  10.1016/j.bbagen.2019.03.021
- Peer Reviewed
- Data Source
  KAKENHI-WRAPUP-19H05451, KAKENHI-PROJECT-16K07326
[Journal Article] Direct observation of ligand migration within human hemoglobin at work2020
- Author(s)
  Shibayama Naoya、Sato-Tomita Ayana、Ohki Mio、Ichiyanagi Kouhei、Park Sam-Yong
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 117 Issue: 9 Pages: 4741-4748
- DOI
  10.1073/pnas.1913663117
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06601, KAKENHI-PLANNED-17H06372, KAKENHI-WRAPUP-19H05451, KAKENHI-PROJECT-16K07326, KAKENHI-PLANNED-19H05779, KAKENHI-PROJECT-17H06141, KAKENHI-PROJECT-18H02413
[Journal Article] Size and Shape Controlled Crystallization of Hemoglobin for Advanced Crystallography2017
- Author(s)
  Ayana Sato-Tomita、Naoya Shibayama
- Journal Title
  
  Crystals
  
  Volume: 7 Issue: 9 Pages: 282-282
- DOI
  10.3390/cryst7090282
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07326, KAKENHI-INTERNATIONAL-15K21719, KAKENHI-PLANNED-17H06372, KAKENHI-ORGANIZER-26105001
[Journal Article] Direct observation of conformational population shifts in crystalline human hemoglobin2017
- Author(s)
  Shibayama Naoya、Ohki Mio、Tame Jeremy R. H.、Park Sam-Yong
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 292 Issue: 44 Pages: 18258-18269
- DOI
  10.1074/jbc.m117.781146
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07326, KAKENHI-INTERNATIONAL-15K21719, KAKENHI-ORGANIZER-26105001
[Journal Article] Molecular mechanism of photoactivation of a light-regulated adenylate cyclase2017
- Author(s)
  Ohki Mio、Sato-Tomita Ayana、Matsunaga Shigeru、Iseki Mineo、Tame Jeremy R. H.、Shibayama Naoya、Park Sam-Yong
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 114 Issue: 32 Pages: 8562-8567
- DOI
  10.1073/pnas.1704391114
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07326, KAKENHI-PROJECT-17K15076, KAKENHI-INTERNATIONAL-15K21719, KAKENHI-ORGANIZER-26105001
[Journal Article] Development of an X-ray fluorescence holographic measurement system for protein crystals”2016
- Author(s)
  A. Sato-Tomita, N. Shibayama, N. Happo, K. Kimura, T. Okabe, T. Matsushita, S.-Y. Park, Y. C. Sasaki, K. Hayashi, ,
- Journal Title
  
  Rev. Sci. Inst.
  
  Volume: 87 Issue: 6 Pages: 063707-063707
- DOI
  10.1063/1.4953453
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-ORGANIZER-26105001, KAKENHI-PLANNED-26105005, KAKENHI-PLANNED-26105013, KAKENHI-INTERNATIONAL-15K21719, KAKENHI-PLANNED-26105006
[Journal Article] Capturing the Hemoglobin Allosteric Transition in a Single Crystal Form2014
- Author(s)
  Naoya Shibayama, Kanako Sugiyama, Jeremy R. H. Tame, and Sam-Yong Park.
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 136 (13) Issue: 13 Pages: 5097-5105
- DOI
  10.1021/ja500380e
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570197, KAKENHI-PROJECT-25291016
[Journal Article] Symmetry Distortion in the Human Hemoglobin Tetramer Induced by Asymmetric Ligation2012
- Author(s)
  Naoya Shibayama.
- Journal Title
  
  FEBS Letters
  
  Volume: 586(1) Issue: 1 Pages: 74-78
- DOI
  10.1016/j.febslet.2011.11.027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570197
[Journal Article] Structures and Oxygen Affinities of Crystalline Human Hemoglobin C (β6 Glu→Lys) in the R and R2 Quaternary Structures2011
- Author(s)
  Naoya Shibayama, Kanako Sugiyama, and Sam-Yong Park.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 286(38) Issue: 38 Pages: 33661-33668
- DOI
  10.1074/jbc.m111.266056
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570197
[Journal Article] Structures and oxygen affinities of crystalline human hemoglobin C (β6 Glu→Lys) in the R and R2 quaternary structures2011
- Author(s)
  Naoya Shibayama, Kanako Sugiyama, and Park Sam-Yong
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 286 Pages: 33661-33668
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570197
[Journal Article] Slow motion analysis of protein folding intermediates within wet silica gels2008
- Author(s)
  Naoya, Shibayama
- Journal Title
  
  Biochemistry (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570135
[Journal Article] Slow motion analysis of protein intermediates within wet silica gels2008
- Author(s)
  Naoya Shibayama
- Journal Title
  
  Biochemistry (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17570135
[Journal Article] Slow motion analysis of protein folding intermediates within wet silica gels2008
- Author(s)
  Naoya Shibayama
- Journal Title
  
  Biochemistry (印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17570135
[Presentation] Fe-Tyr 配位結合をもつ 4 種類の天然変異ヘモグロビン M の結晶構造2023
- Author(s)
  Shigenori Nagatomo, Ayana Sato-Tomita, Yumi Semba, Akihisa Miyagawa, Kiyoharu Nakatani, Mio Ohki, Kenji Mizutani, Sam-Yong Park, Naoya Shibayama
- Organizer
  第６１回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-19K06601
[Presentation] ヘモグロビンM IwateとM BostonのFe-O伸縮振動の理論計算の改良およびヘモグロビンAとの構造の比較2023
- Author(s)
  長友重紀、寺田拓人、庄司光男、重田育照、中谷清治、廣田俊、柳澤幸子、久保稔、北川禎三、長井雅子、大木規央、朴三用、柴山修哉
- Organizer
  第４９回生体分子科学討論会
- Data Source
  KAKENHI-PROJECT-19K06601
[Presentation] いまさらヘモグロビン？2023
- Author(s)
  柴山　修哉
- Organizer
  低酸素研究会2023
- Invited
- Data Source
  KAKENHI-PROJECT-19K06601
[Presentation] Allosteric transition dynamics in hemoglobin Reconsidered by Diffracted X-ray Tracking2022
- Author(s)
  関口博史,山本直樹,柴山修哉,佐々木裕次
- Organizer
  第60回日本生物物理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-20H00324
[Presentation] ヘモグロビンの構造・機能・動態研究の最前線2022
- Author(s)
  柴山修哉
- Organizer
  第29回日本血液代替物学会年次大会
- Invited
- Data Source
  KAKENHI-PROJECT-20H00324
[Presentation] ヘモグロビンの構造・機能・動態研究の最前線2022
- Author(s)
  柴山　修哉
- Organizer
  第29回日本血液代替物学会年次大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K06601
[Presentation] ヘモグロビンM IwateとM Bostonにおけるヘム-チロシン結合の振動分光，結晶構造，理論計算による解析2021
- Author(s)
  長友　重紀，寺田　拓人，庄司　光男，重田　育照，中谷　清治，廣田　俊，北川　禎三，長井　雅子，大木　規央，朴　三用，柴山　修哉
- Organizer
  第47回生体分子科学討論会
- Data Source
  KAKENHI-PROJECT-19K06601
[Presentation] ヘモグロビンの超精密制御機構の秘密2021
- Author(s)
  柴山　修哉
- Organizer
  第33 回生物無機化学夏季セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-19K06601
[Presentation] Comprehensive structural and functional analysis of hemoglobin in single crystals2018
- Author(s)
  柴山　修哉
- Organizer
  日本生物物理学会第56回年会
- Invited
- Data Source
  KAKENHI-PROJECT-16K07326
[Presentation] Deciphering protein allosteric mechanisms from small structural changes in crystals2017
- Author(s)
  Naoya Shibayama, Ayana Sato,　Mio Ohki, Sam-Yong Park
- Organizer
  日本生物物理学会第55回年会
- Data Source
  KAKENHI-PROJECT-16K07326
[Presentation] X-RAY FLUORESCENCE HOLOGRAPHY FOR PROTEINS: APPLICATION TO HEMOGLOBIN AND MYOGLOBIN2017
- Author(s)
  Ayana Sato-Tomita, Naohisa Happo, Sam-Yong Park, Koichi Hayashi, Yuji C. Sasaki and Naoya Shibayama
- Organizer
  Annual Meeting of Biophysical Society
- Place of Presentation
  ニューオリンズ（米国）
- Year and Date
  2017-02-11
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26105005
[Presentation] Changes in the picosecond dynamics of hemoglobin related to the structural states2016
- Author(s)
  Satoru Fujiwara，　Toshiyuki Chatake，　Tatsuhito Matsuo，　Fumiaki Kono，　Taiki Tominaga, Kaoru Shibata, Ayana Sato, Naoya Shibayama
- Organizer
  日本生物物理学会第５４回年会
- Place of Presentation
  つくば国際会議場（茨城県つくば市）
- Year and Date
  2016-11-25
- Data Source
  KAKENHI-PUBLICLY-15H01646
[Presentation] Direct observatio of large-scale quaternary motions of hemoglobin in a crystalline state2016
- Author(s)
  Naoya Shibayama, Mio Ohki, and Sam-Yong Park
- Organizer
  日本生物物理学会第５４回年会
- Place of Presentation
  つくば国際会議場（茨城県つくば市）
- Year and Date
  2016-11-25
- Data Source
  KAKENHI-PUBLICLY-15H01646
[Presentation] Direct observation of large-scale quaternary motions of hemoglobin in a crystalline state2016
- Author(s)
  Naoya Shibayama, Mio Ohki, Sam-Yong Park
- Organizer
  日本生物物理学会第５４回年会
- Place of Presentation
  つくば国際会議場（茨城県つくば市）
- Year and Date
  2016-11-25
- Data Source
  KAKENHI-PROJECT-16K07326
[Presentation] 大規模構造変化を許容する結晶：結晶中タンパク質の動きの観測を目指して2015
- Author(s)
  柴山修哉
- Organizer
  日本生物物理学会
- Place of Presentation
  金沢大学角間キャンパス
- Year and Date
  2015-09-13
- Data Source
  KAKENHI-PUBLICLY-15H01646
[Presentation] 単一結晶形中でのヘモグロビンのアロステリック転移2013
- Author(s)
  柴山修哉
- Organizer
  第51回日本生物物理学会年会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2013-10-29
- Data Source
  KAKENHI-PROJECT-23570197
[Presentation] Hemoglobin allosteric transition in a single crystal form2013
- Author(s)
  Naoya Shibayama
- Organizer
  日本生物物理学会第５１回年会
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-23570197
[Presentation] ヘモグロビンのアロステリック平衡のリアルな描像2012
- Author(s)
  柴山修哉, 朴三用
- Organizer
  第50回日本生物物理学会年会
- Place of Presentation
  名古屋大学・東山キャンパス
- Year and Date
  2012-09-24
- Data Source
  KAKENHI-PROJECT-23570197
[Presentation] ヘモグロビンのアロステリック平衡のリアルな描像2012
- Author(s)
  柴山修哉
- Organizer
  第５０回日本生物物理学会年会
- Place of Presentation
  名古屋大学
- Data Source
  KAKENHI-PROJECT-23570197
[Presentation] 2種類のリラックス状態ヘモグロビン結晶の機能比較2011
- Author(s)
  柴山修哉
- Organizer
  第49回日本生物物理学会年会
- Place of Presentation
  兵庫県立大学・姫路書写キャンパス
- Year and Date
  2011-09-16
- Data Source
  KAKENHI-PROJECT-23570197
[Presentation] ２種類のリラックス状態ヘモグロビン結晶の機能比較2011
- Author(s)
  柴山修哉
- Organizer
  第４９回日本生物物理学会年会
- Place of Presentation
  兵庫県立大学
- Data Source
  KAKENHI-PROJECT-23570197
[Presentation] タンパク質折れたたみ運動のスローモーション解析:多孔性ゲルを用いて折れたたみ初期のダウンヒル過程を観る2006
- Author(s)
  柴山修哉
- Organizer
  阪大蛋白研セミナー:蛋白質の機能運動と折り畳み運動
- Place of Presentation
  阪大蛋白研
- Year and Date
  2006-09-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570135
[Presentation] 多孔性ゲルを用いたタンパク質ダイナミクスのスローモーション化2006
- Author(s)
  柴山修哉
- Organizer
  自治医科大学シンポジウム
- Place of Presentation
  自治医科大学
- Year and Date
  2006-09-02
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570135
[Presentation] Slow motion analysis of protein folding dynamics : Watching the early downhill process in protein folding2006
- Author(s)
  Naoya, Shibayama
- Organizer
  IPR Seminar : Protein Dynamics in Folding and Function
- Place of Presentation
  Institute for Protein Research, Osaka University
- Year and Date
  2006-09-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570135
[Presentation] Deceleration of protein dynamics using wet, porous silica gels2006
- Author(s)
  Naoya, Shibayama
- Organizer
  Jichi Medical University Symposium
- Place of Presentation
  Jichi Medical University
- Year and Date
  2006-09-02
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570135
[Presentation] Protein folding monitored by slow motion2005
- Author(s)
  Naoya, Shibayama
- Organizer
  The 43th Annual Meeting of the Biophysical. Society of Japan
- Place of Presentation
  Sapporo Convention Center
- Year and Date
  2005-11-25
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570135
[Presentation] スローモーションでみたタンパク質の折れたたみ運動2005
- Author(s)
  柴山修哉
- Organizer
  第6回生体分子のダイナミクス研究会
- Place of Presentation
  東京大学農学部
- Year and Date
  2005-07-26
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570135
[Presentation] Protein folding monitored by slow motion2005
- Author(s)
  Naoya, Shibayama
- Organizer
  The 6th Symposium of the Society for the Dynamics of Biomolecules
- Place of Presentation
  Faculty of Agriculture, Tokyo University
- Year and Date
  2005-07-25
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570135
[Presentation] スローモーションでみたタンパク質の折れたたみ運動2005
- Author(s)
  柴山修哉
- Organizer
  第43回日本生物物理学会年
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2005-11-25
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570135

1. 西郷敏 (70049071)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. PARK Sam-yong (20291932)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
3. Sasaki Yuji (30344401)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
4. 松下正 (40092332)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 関口博史 (00401563)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
6. 宮澤淳夫 (60247252)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 久保泰 (10178030)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 一柳光平 (70435618)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 林好一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 松下智裕

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shibayama Naoya 柴山 修哉

柴山 修哉 シバヤマ ナオヤ

SHIBAYAMA Naoya 柴山 修哉

Research Projects

Research Products

Co-Researchers

Determination of single hemoglobin dynamics with x-rays

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Semi-comprehensive functional determination of crystal structures of hemoglobinPrincipal Investigator

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Direct observation of ligand and protein dynamics within hemoglobin at workPrincipal Investigator

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ヘモグロビンの四次構造変化を許容する結晶を用いた時分割構造解析法の開拓Principal Investigator

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3D Active Site Science in Biology

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Elucidation of the true picture of the hemoglobin allosteric equilibriumPrincipal Investigator

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タイマータンパク質EA4の計時機構解明を目指した研究Principal Investigator

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Slow motion analysis of the fokling reactions of proteins within wet silica gelsPrincipal Investigator

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ゾル・ゲル包括法によるタンパク質分子の構造・機能解析Principal Investigator

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多孔性ゲルによるタンパク質の微視的構造状態の機能解析Principal Investigator

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多孔性ガラスによるタンパク質の高次構造固定法を用いたタンパク質機能の研究Principal Investigator

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多孔性ガラスによるタンパク質の高次構造固定法の開発と2状態モデルの直接的検証Principal Investigator

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架橋混成ヘモグロビンを用いたアロステリック効果の研究Principal Investigator

Principal Investigator

Shibayama Naoya 柴山修哉

柴山修哉シバヤマナオヤ

SHIBAYAMA Naoya 柴山修哉