Tan-no Koichi 丹野孝一

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TAN-NO Koichi 丹野孝一

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Researcher Number	20207260
Other IDs
External Links
Affiliation (Current)	2025: 東北医科薬科大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2025: 東北医科薬科大学, 薬学部, 教授 2016 – 2023: 東北医科薬科大学, 薬学部, 教授 2014 – 2015: 東北薬科大学, 薬学部, 教授 2011 – 2012: 東北薬科大学, 薬学部, 教授 2007 – 2010: Tohoku Pharmaceutical University, 薬学部, 准教授 … More 2006: 東北薬科大学, 薬学部, 助教授 2002 – 2004: 東北薬科大学, 薬学部, 講師 1996: 東北薬科大学, 薬学部, 助手 1996: Tohoku Coll.of Pharmacy, Pharmacology, Assistant, 薬理学, 助手 1995: 東北薬科大学, 薬学部・薬理学, 助手 Less
Review Section/Research Field	Principal Investigator Basic Section 47040:Pharmacology-related / Biological pharmacy / Pharmacology in pharmacy / 疼痛学 / Pain science Except Principal Investigator Basic Section 47040:Pharmacology-related / Drug development chemistry / Pharmacology in pharmacy / 疼痛学
Keywords	Principal Investigator マウス / p38 MAPK / 糖尿病性神経障害性疼痛 / 神経障害性疼痛 / 2型糖尿病 / ob/obマウス / 脊髄 / Mas受容体 / アンジオテンシン (1-7) / アンジオテンシン変換酵素2 … More / ダイノルフィンA / アンジオテンシンII / ホルマリン試験 / 慢性疼痛 / 疼痛関連行動 / NMDA受容体 / 一酸化窒素 / 脊髄クモ膜下腔内投与 / ダイノルフィン / 鎮痛耐性 / モルヒネ / アンジオテンシン（1-7） / レプチン受容体欠損 (db/db) マウス / アンジオテンシン変換酵素2 (ACE2) / レプチン欠損 (ob/ob) マウス / テルミサルタン / ペリンドプリルエルブミン / ACE2 / 機械的アロデニィア / 熱性痛覚過敏 / 接触性痛覚過敏 / ストレプトゾトシン / Nociceptive behavior / Prodynorphin knockout mice / Intrathecal administration / Polyamine recognition site / NMDA receptor ion-channel complex / N-Ethylmaleimide / Poly-L-lysine / Big dynorphin / NMDA受容体関連拮抗薬 / NMDA受容体複合体 / ダイノルフィン類 / 侵害行動 / プロダイノルフィン欠損マウス / ポリアミン調節部位 / NMDA受容体イオンチャネル複合体 / N-エチルマレイミド / ポリ-L-リジン / ビッグダイノルフィン / Capsaicin test / Formalin test / Protease / p-Hydroxymercuribenzoate / Enkephalin / Dynorphin / ダイノルフィン変換酸素 / ペプチダーゼ阻害剤 / ダイノルフィンB / p-ハイドロキシメルクリ安息香酸 / カプサイシン試験 / プロテアーゼ / P-ヒドロキシメルクリ安息香酸 / エンケファリン / 抗アロディニア作用 / 1型糖尿病 / ロサルタン / AT1受容体 / アンジオテンシン変換酵素 / アンジオテンシンⅡ / １型糖尿病 / NOS1AP / DNAマイクロアレイ解析 / L型カルシウムチャネル / AMPA受容体 / 炎症性疼痛 / 身体的依存 / 脊髄クモ膜下腔内 / D-サイクロセリン / グリシン調節部位 / カスペース / p53 / システインプロテアーゼ / 神経因性疼痛 … More Except Principal Investigator 脊髄 / 疼痛 / db/dbマウス / 神経障害 / 糖尿病 / TNF-α変換酵素 / i医薬分子設計 / レチノイドX受容体 / アンタゴニスト / アゴニスト / アンドロゲン受容体 / エストロゲン受容体 / 核内受容体 / 医薬分子設計 / 嗅球摘出 / スカブロニン / 海馬歯状回 / 嗅球摘出動物 / 記憶障害 / うつ / 動物モデル / 脳由来神経栄養因子 / うつ病 / 認知症 / 神経新生 / 疼痛関連行動 / アンジオテンシンII Less

脊髄アンジオテンシン系は難治性疼痛に対する新規治療標的になり得るか？Principal Investigator
- Principal Investigator
  
  丹野孝一
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Tohoku Medical and Pharmaceutical University
脊髄内TNF-α変換酵素による細胞外領域シェディングを介した疼痛制御機構
- Principal Investigator
  
  根本亙
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Tohoku Medical and Pharmaceutical University
Elucidation of neuropathic pain associated with type 2 diabetes mellitus: Involvement of spinal angiotensin system and development of the novel therapeutic agentsPrincipal Investigator
- Principal Investigator
  
  Tan-No Koichi
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Tohoku Medical and Pharmaceutical University
Elucidation of the mechanism underlying diabetic neuropathic pain and development of its new therapy: Examination from the viewpoint of spinal angiotensin systemPrincipal Investigator
- Principal Investigator
  
  Tan-No Koichi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Tohoku Medical and Pharmaceutical University
Elucidation of the role of spinal angiotensin system in chronic pain: Aim at developing the new therapyPrincipal Investigator
- Principal Investigator
  
  TAN-NO Koichi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Tohoku Medical and Pharmaceutical University
Development of hippocampal neurogenesis-promoting drugs as a target for the treatment and prevention of psychiatric disorders
- Principal Investigator
  
  NAKAGAWASAI Osamu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Tohoku Medical and Pharmaceutical University
A New Development of Molecular Design Utilizing Novel Hydrophobic Structures
- Principal Investigator
  
  ENDO Yasuyuki
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Tohoku Medical and Pharmaceutical University
The role of angiotensin II in nociceptive transmission in the spinal cord
- Principal Investigator
  
  NAKAGAWASAI Osamu
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  疼痛学
- Research Institution
  Tohoku Pharmaceutical University
Elucidation of the mechanism underlying the suppression of the development of analgesic tolerance to morphine under chronic painPrincipal Investigator
- Principal Investigator
  
  TAN-NO Koichi
- Project Period (FY)
  2009 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  疼痛学
- Research Institution
  Tohoku Pharmaceutical University
Elucidation of chronic pain mechanism from interactions between spinaI dynorphin system and p53, a transcription factorPrincipal Investigator
- Principal Investigator
  
  TAN-NO Koichi
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pain science
- Research Institution
  Tohoku Pharmaceutical University
The study of behavioral pharmacology, cellular and molecular biology on big dynorphin-induced painful paresthesia.Principal Investigator
- Principal Investigator
  
  TAN-NO Koichi
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tohokn Phaimaceulical University
Pharmacological Study of Substance P and Dynorphin on the Spinal Regulation of Nociceptive InformationPrincipal Investigator
- Principal Investigator
  
  TAN-NO Koichi
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tohoku College of Pharmacy

[Book] オピオイド研究の進歩と展望2004
- Author(s)
  丹野孝一
- Total Pages
  222
- Publisher
  ネオメディカル
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14572062
[Journal Article] Clinical and preclinical evidence that angiotensin-converting enzyme inhibitors and angiotensin receptor blockers prevent diabetic peripheral neuropathy2024
- Author(s)
  Iwane Shiori、Nemoto Wataru、Miyamoto Tomoyoshi、Hayashi Tomonori、Tanaka Masayuki、Uchitani Kazuki、Muranaka Tatsuya、Fujitani Masanori、Koizumi Yuichi、Hirata Atsushi、Tsubota Maho、Sekiguchi Fumiko、Tan-No Koichi、Kawabata Atsufumi
- Journal Title
  
  Scientific Reports
  
  Volume: 14 Issue: 1 Pages: 1039-1039
- DOI
  10.1038/s41598-024-51572-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06168, KAKENHI-PROJECT-20K07074
[Journal Article] Angiotensin-Related Peptides and Their Role in Pain Regulation2023
- Author(s)
  Nemoto Wataru、Yamagata Ryota、Nakagawasai Osamu、Tan-No Koichi
- Journal Title
  
  Biology
  
  Volume: 12 Issue: 5 Pages: 755-755
- DOI
  10.3390/biology12050755
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06168, KAKENHI-PROJECT-20K07074
[Journal Article] Low Skeletal Muscle Mass Is Associated With Perioperative Neurocognitive Disorder Due To Decreased Neurogenesis in Rats2021
- Author(s)
  Nemoto Akira、Goyagi Toru、Nemoto Wataru、Nakagawasai Osamu、Tan-No Koichi、Niiyama Yukitoshi
- Journal Title
  
  Anesthesia & Analgesia
  
  Volume: 134 Issue: 1 Pages: 194-203
- DOI
  10.1213/ane.0000000000005681
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08808, KAKENHI-PROJECT-20K07074
[Journal Article] Angiotensin (1–7) Attenuates the Nociceptive Behavior Induced by Substance P and NMDA <i>via</i> Spinal MAS12021
- Author(s)
  Ryota Yamagata, Wataru Nemoto, Maho Fujita, Osamu Nakagawasai, Koichi Tan-No
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 44 Issue: 5 Pages: 742-746
- DOI
  10.1248/bpb.b20-01004
- NAID
  130008033239
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2021-05-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07074, KAKENHI-PROJECT-19K16376
[Journal Article] Downregulation of spinal angiotensin converting enzyme 2 is involved in neuropathic pain associated with type 2 diabetes mellitus in mice2020
- Author(s)
  Yamagata Ryota、Nemoto Wataru、Nakagawasai Osamu、Takahashi Kohei、Tan-No Koichi
- Journal Title
  
  Biochemical Pharmacology
  
  Volume: 174 Pages: 113825-113825
- DOI
  10.1016/j.bcp.2020.113825
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K16376, KAKENHI-PROJECT-17K08313, KAKENHI-PROJECT-20K07074
[Journal Article] Effect of spinal angiotensin-converting enzyme 2 activation on the formalin-induced nociceptive response in mice2020
- Author(s)
  Nemoto Wataru、Yamagata Ryota、Nakagawasai Osamu、Nakagawa Koharu、Hung Wan-Yi、Fujita Maho、Tadano Takeshi、Tan-No Koichi
- Journal Title
  
  European Journal of Pharmacology
  
  Volume: 872 Pages: 172950-172950
- DOI
  10.1016/j.ejphar.2020.172950
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K16376, KAKENHI-PROJECT-17K08313, KAKENHI-PROJECT-20K07074
[Journal Article] Anti-hypersensitive effect of angiotensin (1-7) on streptozotocin-induced diabetic neuropathic pain in mice2019
- Author(s)
  Yoshiki Ogata, Wataru Nemoto, Ryota Yamagata, Osamu Nakagawasai, Shuji Shimoyama, Tomonori Furukawa, Shinya Ueno, Koichi Tan-No
- Journal Title
  
  Eur. J. Pain
  
  Volume: 23 Issue: 4 Pages: 739-749
- DOI
  10.1002/ejp.1341
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08313, KAKENHI-PROJECT-18K08846, KAKENHI-PROJECT-16K20888, KAKENHI-PROJECT-16K21311, KAKENHI-PROJECT-18K15356
[Journal Article] Inhibitory effect of angiotensin (1-7) on angiotensin III-induced nociceptive behaviour in mice2017
- Author(s)
  Nemoto W., Yamagata R., Ogata Y., Nakagawasai O., Tadano T., Tan-No K.
- Journal Title
  
  Neuropeptides
  
  Volume: 65 Pages: 71-76
- DOI
  10.1016/j.npep.2017.05.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08313, KAKENHI-PROJECT-16K21311
[Journal Article] Involvement of spinal angiotensin II system in streptozotocin-induced diabetic neuropathic pain in mice.2016
- Author(s)
  Ogata Y, Nemoto W, Nakagawasai O, Yamagata R, Tadano T, Tan-No K.
- Journal Title
  
  Molecular Pharmacology
  
  Volume: 90 Issue: 3 Pages: 205-213
- DOI
  10.1124/mol.116.104133
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460101, KAKENHI-PROJECT-16K21311
[Journal Article] Alterations in behavioral responses to dopamine agonists in olfactory bulbectomized mice: relationship to changes in the striatal dopaminergic system2016
- Author(s)
  Kohei Takahashi, Osamu Nakagawasai, Wataru Nemoto, Takeharu Nakajima, Yuichiro Arai, Tadashi Hisamitsu, Koichi Tan-No
- Journal Title
  
  Psychopharmacology
  
  Volume: 233 Issue: 7 Pages: 1311-1322
- DOI
  10.1007/s00213-016-4224-y
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460102
[Journal Article] BE360, a new selective estrogen receptor modulator, produces antidepressant and antidementia effects through the enhancement of hippocampal cell proliferation in olfactory bulbectomized mice.2016
- Author(s)
  Osamu Nakagawasai, Wataru Nemoto, Hiroshi Onogi, Takahiro Moriya, Jia-Rong Lin, Takayo Odaira, Fukie Yaoita, Takumi Ogawa, Kiminori Ohta, Yasuyuki Endo, Koichi Tan-No
- Journal Title
  
  Behav Brain Res
  
  Volume: 297 Pages: 315-322
- DOI
  10.1016/j.bbr.2015.10.033
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460102, KAKENHI-PROJECT-26461709, KAKENHI-PROJECT-26460151
[Journal Article] Involvement of p38 MAPK activation mediated through AT1 receptors on spinal astrocytes and neurons in angiotensin II- and III-induced nociceptive behavior in mice.2015
- Author(s)
  Wataru Nemoto, Yoshiki Ogata, Osamu Nakagawasai, Fukie Yaoita, Takeshi Tadano, Koichi Tan-No
- Journal Title
  
  Neuropharmacology
  
  Volume: 99 Pages: 221-231
- DOI
  10.1016/j.neuropharm.2015.07.022
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460101
[Journal Article] The intrathecal administration of losartan, an AT1 receptor antagonist, produces an antinociceptive effect through the inhibiton of p38 MAPK phosphorylation in the mouse formalin test.2015
- Author(s)
  Wataru Nemoto, Yoshiki Ogata, Osamu Nakagawasai, Fukie Yaoita, Takeshi Tadano, Koichi Tan-No
- Journal Title
  
  Neurosci. Lett.
  
  Volume: 585 Pages: 17-22
- DOI
  10.1016/j.neulet.2014.11.018
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460101
[Journal Article] Angiotensin (1-7) prevents angiotensin II-induced nociceptive behaviour via inhibition of p38 MAPK phosphorylation mediated through spinal Mas receptors in mice.2014
- Author(s)
  Wataru Nemoto, Yoshiki Ogata, Osamu Nakagawasai, Fukie Yaoita, Takeshi Tadano, Koichi Tan-No
- Journal Title
  
  Eur. J. Pain
  
  Volume: 18 Issue: 10 Pages: 1471-1479
- DOI
  10.1002/ejp.512
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460101
[Journal Article] Phenylmethanesulfonyl fluoride, a serine protease inhibitor, suppresses naloxone-precipitated withdrawal jumping in morphine-dependent mice2013
- Author(s)
  Nemoto W ., Sato T ., Nakagawasai O., Yaoita F ., Silberring J., Tadano T , Tan-No K
- Journal Title
  
  Neuropeptides
  
  Volume: 47 Issue: 3 Pages: 187-191
- DOI
  10.1016/j.npep.2012.11.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21600012, KAKENHI-PROJECT-24700433
[Journal Article] Chronic fluvoxamine treatment changes 5-HT_<2A/2C>receptor-mediated behavior in olfactory bulbectomized mice2012
- Author(s)
  Oba A, Nakagawasai O, Onogi H, NemotoW, Yaoita F, Arai Y, Tan-No K, Tadano T
- Journal Title
  
  Life Sci
  
  Volume: 92巻 Issue: 2 Pages: 119-124
- DOI
  10.1016/j.lfs.2012.11.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22600010
[Journal Article] Pharmacological evaluation of catalepsy in low calcium and/or magnesium deficient feeding mice2012
- Author(s)
  Nakagawasai O, Taniguchi R, Tan-No K,Yamadera F, Nemoto W, Yaoita F, TadanoT
- Journal Title
  
  Health
  
  Volume: 4巻 Issue: 11 Pages: 1138-1144
- DOI
  10.4236/health.2012.431172
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22600010
[Journal Article] Intraplantar injection of gangliosides produces nociceptive behavior and hyperalgesia via a glutamate signaling mechanism2011
- Author(s)
  Watanabe S., Tan-No K., Tadano T., Higashi H
- Journal Title
  
  Pain
  
  Volume: 152 Issue: 2 Pages: 327-334
- DOI
  10.1016/j.pain.2010.10.036
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21600012
[Journal Article] p-Hydroxyamphetamine causes prepulse inhibition disruption in mice: contribution of serotonin neurotransmission2011
- Author(s)
  Onogi H, Nakagawasai O, Sato A, Mitazaki S, Nakaya K, Watanabe K, Niijima-Yaoita F, Tan-No K, Arai Y, Kikuchi T, Tadano T
- Journal Title
  
  Behav Brain Res
  
  Volume: 224巻 Issue: 1 Pages: 159-165
- DOI
  10.1016/j.bbr.2011.06.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22600010
[Journal Article] モルヒネの鎮痛耐性および身体的依存形成におけるシステインプロテアーゼの関与2011
- Author(s)
  丹野孝一
- Journal Title
  
  東北薬科大学研究誌
  
  Volume: 58号 Pages: 29-34
- NAID
  110009512413
- URL
  http://ci.nii.ac.jp/vol_issue/nels/AA1149311X_jp.html
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21600012
[Journal Article] Suppressive effects by cysteine protease inhibitors on naloxone-precipitated withdrawal jumping in morphine-dependent mice2010
- Author(s)
  Tan-No K., Sato T., Shimoda M., Nakagawasai O., Niijima F., KawamuraS., Furuta S., Sato T., Satoh S., Silberring J., Terenius L., Takeshi Tadano
- Journal Title
  
  Neuropeptides
  
  Volume: 44 Issue: 3 Pages: 279-283
- DOI
  10.1016/j.npep.2010.02.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21600012, KAKENHI-PROJECT-22600010
[Journal Article] Suppressive effects by cysteine protease inhibitors on naloxone-precipitated withdrawal jumping in morphine-dependent mice2010
- Author(s)
  Tan-No K, Sato T, Shimoda M, Nakagawasai O, 他8名
- Journal Title
  
  Neuropeptides
  
  Volume: 44 Pages: 279-283
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22600010
[Journal Article] Nociceptive behavior induced by the endogenous opioid peptides dynorphins in uninjured mice : Evidence with intrathecal N-ethylmaleimide inhibiting dynorphin degradation.2009
- Author(s)
  Koichi Tan-No
- Journal Title
  
  International Review of Neurobiology 85
  
  Pages: 189-203
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21600012
[Journal Article] Nociceptive behavior induced by the endogenous opioid peptides dynorphins in uninjured mice: evidence with intrathecal N-ethylmaleimide inhibiting dynorphin degradation2009
- Author(s)
  Tan-No K., Takahashi H., NakagawasaiO., Niijima F., Sakurada S., Bakalkin G., Terenius L., Tadano T
- Journal Title
  
  Int. Rev. Neurobiol
  
  Volume: 85 Pages: 191-205
- DOI
  10.1016/s0074-7742(09)85015-0
- ISBN
  9780123748935
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21600012
[Journal Article] Nociceptive behavior induced by the endogenous opioid peptides dynorphins in uninjured mice : evidence with intrathecal N-ethylmaleimide inhibiting dynorphin degradation2009
- Author(s)
  Tan-No, K., Takahashi, H., Nakagawasai, O., Niijima, F., Sakurada, S., Bakalkin, G., Terenius, L., Tadano, T
- Journal Title
  
  Int. Rev. Neurobiol 85
  
  Pages: 189-203
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18613016
[Journal Article] Involvement of the p53 tumor-suppressor protein in the development of antinociceptive tolerance to morphine2009
- Author(s)
  Tan-No, K., Shimoda, M., Watanabe, K.,Nakagawasai, O., Niijima, F., Kanno, S.,Ishikawa, M., Bakalkin, G., Tadano, T
- Journal Title
  
  Neurosci. Lett 450
  
  Pages: 365-368
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18613016
[Journal Article] Involvement of the p53 tumor-suppressor protein in the development of antinociceptive tolerance to morphine.2009
- Author(s)
  Koichi Tan-No
- Journal Title
  
  Neuroscience Letters 450
  
  Pages: 365-368
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18613016
[Journal Article] Cysteine protease inhibitors suppress the development of tolerance to morphine antinociception2008
- Author(s)
  Tan-No, K., Shimoda, M., Sugawara, M.,Nakagawasai, O., Niijima, F., Watanabe,H., Furuta, S., Sato, T., Satoh, S., Arai,Y., Kotlinska, J., Silberring, J.,Terenius, L., Tadano, T
- Journal Title
  
  Neuropeptides 42
  
  Pages: 239-244
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18613016
[Journal Article] Cysteine protease inhibitors suppress the development of tolerance to morphine antinociception.2008
- Author(s)
  Koichi Tan-No
- Journal Title
  
  Neuropeptides 42
  
  Pages: 239-244
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18613016
[Journal Article] Cysteine protease inhibitors suppress the development of tolerance tomorphine antinociception2008
- Author(s)
  Koichi Tan-No
- Journal Title
  
  Neuropeptides (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18613016
[Journal Article] S-(+)-Fenfluramine-induced nociceptive behavior in mice : involvement of interactions between spinal serotonin and substance P systems2007
- Author(s)
  Tan-No, K., Takahashi, K., Shimoda, M., Sugawara, M., Nakagawasai, O., Niijima, F., Sato, T., Satoh, S., Tadano, T
- Journal Title
  
  Neuropeptides 41
  
  Pages: 33-38
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18613016
[Journal Article] Intrathecally administered D-cycloserine produces nociceptive behavior through the activation of N-methyl-D-aspartate receptor ion-channel complex acting on the glycine recognition site.2007
- Author(s)
  Koichi Tan-No et al.
- Journal Title
  
  J. Pharmacol. Sci. in press
- NAID
  10024313927
- Data Source
  KAKENHI-PROJECT-18613016
[Journal Article] S-(+)-Fenfluramine-induced nociceptive behavior in mice : Involvement of interactions between spinal serotonin and substance P systems.2007
- Author(s)
  Koichi Tan-No et al.
- Journal Title
  
  Neuropeptides 41(1)
  
  Pages: 33-38
- Data Source
  KAKENHI-PROJECT-18613016
[Journal Article] Intrathecally adminstered D-cycloserine produces nociceptive behavior through the activation of N-methyl-D-aspartate receptor ion-channel complex acting on the glycine recognition site2007
- Author(s)
  Koichi Tan-No
- Journal Title
  
  Journal of Pharmacological Sciences 104
  
  Pages: 39-45
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18613016
[Journal Article] Intrathecally administered D-cycloserine produces nociceptive behavior through the activation of N-methyl-D-aspartate receptor ion-channel complex acting on the glycine recognition site2007
- Author(s)
  Tan-No, K., Esashi, A., Nakagawasai, O., Niijima, F., Furuta, S., Sato, T., Satoh, S., Yasuhara, H., Tadano, T
- Journal Title
  
  J. Pharmacol. Sci. 104
  
  Pages: 39-45
- NAID
  10024313927
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18613016
[Journal Article] Anti-inflammatory effect of propolisthrough inhibition of nitric oxide production on carrageenin-induced mouse paw edema2006
- Author(s)
  Tan-No, K., Nakajima, T., Shoji, T., Nakagawasai, O., Niijima, F., Ishikawa, M., Endo, Y., Sato, T., Satoh, S., Tadano, T
- Journal Title
  
  Biol. Pharm. Bull 29
  
  Pages: 96-99
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18613016
[Journal Article] Pronociceptive role of dynorphins in uninjured animals : N-ethylmaleimide-induced nociceptive behavior mediated through inhibition of dynorphin degradation2005
- Author(s)
  Koichi Tan-No
- Journal Title
  
  Pain 113
  
  Pages: 301-309
- Data Source
  KAKENHI-PROJECT-14572062
[Journal Article] Pronociceptive role of dynorphins in uninjured animals : N-ethylmaleimide-induced nociceptive behavior mediated through inhibition of dynorphin degradation.2005
- Author(s)
  Koichi Tan-No
- Journal Title
  
  Pain 113
  
  Pages: 301-309
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14572062
[Journal Article] Pronociceptive role of dynorphins in uninjured animals: N-ethylmaleimide-induced nociceptive behavior mediated through inhibition of dynorphin degradation.2005
- Author(s)
  Koichi Tan-No
- Journal Title
  
  Pain 113
  
  Pages: 301-309
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14572062
[Journal Article] Nociceptive behavior induced by poly-L-lysine and other basic compounds involves the spinal NMDA receptors.2004
- Author(s)
  Koichi Tan-No
- Journal Title
  
  Brain Research 1008
  
  Pages: 49-53
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14572062
[Journal Article] Intrathecal spermine and spermidine at high-doses induce antinociceptive effects in the mouse capsaicin test.2003
- Author(s)
  Koichi Tan-No
- Journal Title
  
  Biogenic Amines 17
  
  Pages: 313-320
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14572062
[Journal Article] Intrathecally administered big dynorphin, a prodynorphin-derived peptide, produces nociceptive behavior through an N-methyl-D-aspartate receptor mechanism.2002
- Author(s)
  Koichi Tan-No
- Journal Title
  
  Brain Research 952
  
  Pages: 7-14
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14572062
[Journal Article] Intrathecally administered administered big dynorphin, a prodynorphin-derived peptide, produces nociceptive behavior through an N-methyl-D-aspartate receptor mechanism.2002
- Author(s)
  Koichi Tan-No
- Journal Title
  
  Brain Research 952
  
  Pages: 7-14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14572062
[Presentation] アンジオテンシン変換酵素阻害薬とAT1受容体拮抗薬による有痛性糖尿病性神経障害の抑制：保険薬局のレセプトデータ解析による検証2024
- Author(s)
  山本卓資、岩根詩織、宮本朋佳、坪田真帆、関口富美子、榊原幹夫、根本亙、丹野孝一、川畑篤史
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-20K07074
[Presentation] 関節炎モデルマウスの痛覚過敏に対する海洋微細藻類Pavlovaの効果2024
- Author(s)
  根本亙，山田耕太郎，小林瑠夏，星友裕，中原剣，金本昭彦，中川西修，丹野孝一
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K06168
[Presentation] 脊髄内ADAM17は2型糖尿病に伴う神経障害性疼痛に関与する2023
- Author(s)
  根本　亙，山縣涼太，中川西修，丹野孝一
- Organizer
  第97回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-23K06168
[Presentation] 高血圧を合併する糖尿病患者における末梢神経障害の発症に対するアンギオテンシン変換酵素阻害薬または受容体拮抗薬の抑制効果：3病院での臨床知見と基礎研究による検証2023
- Author(s)
  冨田詩織，根本亙，宮本朋佳，林友典，田中雅幸，打谷和記，村中達也，小泉祐一，平田敦士，坪田真帆，関口富美子，丹野孝一，川畑篤史
- Organizer
  日本薬学会
- Data Source
  KAKENHI-PROJECT-20K07074
[Presentation] レニン・アンギオテンシン系阻害薬は糖尿病性末梢神経障害の発症を抑制する：3病院での後ろ向きコホート研究と基礎研究での検証2023
- Author(s)
  岩根詩織、根本亙、宮本朋佳、林友典、田中雅幸、打谷和記、小泉祐一、平田敦士、坪田真帆、関口富美子、丹野孝一、川畑篤史
- Organizer
  第33回日本医療薬学会
- Data Source
  KAKENHI-PROJECT-20K07074
[Presentation] Analgesic mechanisms for inflammatory pain by spinal angiotensin (1-7)-generating system2023
- Author(s)
  Wataru Nemoto, Ryota Yamagata, Osamu Nakagawasai, Koharu Nakagawa, Wan-Yi Hung, Maho Fujita, Koichi Tan-No
- Organizer
  34th CINP World Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06168
[Presentation] 脊髄内ADAM17は2型糖尿病に伴う神経障害性疼痛に関与する2023
- Author(s)
  根本亙、山縣涼太、中川西修、丹野孝一
- Organizer
  第97回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20K07074
[Presentation] Analgesic mechanisms for inflammatory pain by spinal angiotensin (1-7)-generating system2023
- Author(s)
  Nemoto Wataru、Yamagata Ryota、Nakagawasai Osamu、Nakagawa Koharu、Hung Wan-Yi、Fujita Maho、Tan-No Koichi
- Organizer
  34th CINP World Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07074
[Presentation] Upregulation of spinal ADAM17 contributes to neuropathic pain associated with type 2 diabetes mellitus in mice.2022
- Author(s)
  Wataru Nemoto, Ryota Yamagata, Osamu Nakagawasai, Koichi Tan-No
- Organizer
  NEURO 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07074
[Presentation] アンギオテンシン変換酵素阻害薬とアンギオテンシンII受容体拮抗薬は糖尿病性末梢神経障害の発症を抑制する：臨床・基礎融合研究によるエビデンス2022
- Author(s)
  冨田詩織，宮本朋佳，田中雅幸，打谷和記，小泉祐一，村中達也，根本　亙，丹野孝一，坪田真帆，関口富美子，川畑篤史
- Organizer
  生体機能と創薬シンポジウム2022
- Data Source
  KAKENHI-PROJECT-20K07074
[Presentation] 糖尿病性神経障害性疼痛の解明：アンジオテンシン (1-7) 系からの検討2020
- Author(s)
  根本　亙、山縣涼太、小潟佳輝、中川西　修、八百板富紀枝、丹野　孝一
- Organizer
  第71回日本薬理学会北部会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07074
[Presentation] 糖尿病性神経障害性疼痛における脊髄内 ADAM17 の関与2020
- Author(s)
  山縣涼太、根本　亙、中川西　修、丹野孝一
- Organizer
  第59回日本薬学会東北支部大会
- Data Source
  KAKENHI-PROJECT-20K07074
[Presentation] 脊髄Angiotensin 系の不均衡が糖尿病性神経障害性疼痛に寄与する2019
- Author(s)
  山縣涼太、根本亙、小潟佳輝、中川西修、八百板富紀枝、丹野孝一
- Organizer
  平成31年度東北医科薬科大学創薬研究センターシンポジウム
- Data Source
  KAKENHI-PROJECT-17K08313
[Presentation] 糖尿病性神経障害性疼痛における脊髄アンジオテンシン系の関与の解明―新たな治療戦略を目指して―2019
- Author(s)
  丹野孝一、小潟佳輝、山縣涼太、根本　亙
- Organizer
  生体機能と創薬シンポジウム2019
- Data Source
  KAKENHI-PROJECT-17K08313
[Presentation] 絞扼性神経損傷マウスにおけるdiminazene aceturateの抗痛覚過敏作用2019
- Author(s)
  Hung WY、根本　亙、中川西修、丹野孝一
- Organizer
  第70回日本薬理学会北部会
- Data Source
  KAKENHI-PROJECT-17K08313
[Presentation] 2型糖尿病マウスの神経障害性疼痛における脊髄アンジオテンシン系の関与2019
- Author(s)
  根本　亙、山縣涼太、丹野孝一
- Organizer
  生体機能と創薬シンポジウム2019
- Data Source
  KAKENHI-PROJECT-17K08313
[Presentation] レプチン欠損マウスの神経障害性疼痛に対するアンジオテンシン (1-7) の効果2019
- Author(s)
  山縣涼太、根本　亙、中川西修、丹野孝一
- Organizer
  第70回日本薬理学会北部会
- Data Source
  KAKENHI-PROJECT-17K08313
[Presentation] レプチン欠損マウスの接触性痛覚過敏に対するアンジオテンシン (1-7) の抑制効果2019
- Author(s)
  山縣涼太、根本　亙、中川西修、丹野孝一
- Organizer
  第58回日本薬学会東北支部大会
- Data Source
  KAKENHI-PROJECT-17K08313
[Presentation] Antinociceptive effect of diminazene aceturate, an angiotensin-converting enzyme 2 activator, in the mouse formalin test2019
- Author(s)
  Nemoto W, Yamagata R, Nakagawasai O, Michimata S, Nakagawa K, Tan-No K
- Organizer
  2019 International Society for Neurochemistry Meeting
- Data Source
  KAKENHI-PROJECT-17K08313
[Presentation] ストレプトゾトシン誘発性糖尿病性神経障害性疼痛に対するAngiotensin (1-7) の抑制効果2019
- Author(s)
  山縣涼太，根本亙，小潟佳輝，中川西修，丹野孝一
- Organizer
  日本薬学会第139年会
- Invited
- Data Source
  KAKENHI-PROJECT-17K08313
[Presentation] Anti-allodynic effect of angiotensin (1-7) on streptozotocin-induced diabetic neuropathic pain2018
- Author(s)
  Ryota Yamagata, Wataru Nemoto, Yoshiki Ogata, Osamu Nakagawasai, Koichi Tan-No
- Organizer
  18th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08313
[Presentation] 2型糖尿病モデルマウスにおけるアンジオテンシン（1-7）の抗痛覚過敏作用2018
- Author(s)
  山縣　涼太，根本　亙，中川西　修，丹野　孝一
- Organizer
  第69回日本薬理学会北部会
- Data Source
  KAKENHI-PROJECT-17K08313
[Presentation] Angiotensin (1-7) prevents streptozotocin-induced diabetic neuropathic pain in mice2018
- Author(s)
  Wataru Nemoto, Yoshiki Ogata, Ryota Yamagata, Osamu Nakagawasai, Koichi Tan-No
- Organizer
  31th European College of Neuropsychopharmacology Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08313
[Presentation] 卵巣摘出マウスのうつ様行動に対する新規選択的エストロゲン受容体モジュレーターBE360の効果2017
- Author(s)
  佐久間若菜，中川西　修，根本　亙，小平貴代，小川卓巳，太田公規，遠藤泰之，只野武，丹野孝一
- Organizer
  第21回活性アミンに関するワークショップ，京都
- Data Source
  KAKENHI-PROJECT-26460151
[Presentation] 糖尿病性神経障害性疼痛に対するアンジオテンシン (1-7) の抑制効果2017
- Author(s)
  山縣涼太，根本　亙，小潟佳輝，中川西　修，八百板富紀枝，丹野孝一
- Organizer
  平成29年度東北医科薬科大学創薬研究センターシンポジウム
- Data Source
  KAKENHI-PROJECT-17K08313
[Presentation] 嗅球摘出マウスの精神機能障害に対する肝臓水解物の効果：海馬AMP活性化プロテインキナーゼの関与について2017
- Author(s)
  中川西修，山田耕太郎，小平貴代，佐久間若菜，根本亙，櫻井英知，丹野孝一
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-26460102
[Presentation] 1型糖尿病モデルマウスにおける神経障害性疼痛に対するアンジオテンシン (1-7) の抑制効果2017
- Author(s)
  山縣涼太，根本　亙，小潟佳輝，中川西　修，丹野孝一
- Organizer
  生体機能と創薬シンポジウム2017
- Data Source
  KAKENHI-PROJECT-17K08313
[Presentation] ストレプトゾトシン誘発性1型糖尿病マウスにおけるアンジオテンシン (1-7) の抗アロディニア作用2017
- Author(s)
  山縣涼太，根本　亙，小潟佳輝，中川西　修，丹野孝一
- Organizer
  第68回日本薬理学会北部会
- Data Source
  KAKENHI-PROJECT-17K08313
[Presentation] 更年期うつ病モデルマウスにおける新規選択的エストロゲン受容体モジュレーターBE360の抗うつ効果2017
- Author(s)
  佐久間若菜，中川西　修，根本　亙，小平貴代，八百板富紀枝，小川卓巳，太田公規，遠藤泰之，丹野孝一
- Organizer
  平成29年度東北医科薬科大学創薬研究センターシンポジウム, 仙台
- Data Source
  KAKENHI-PROJECT-26460151
[Presentation] アンジオテンシン (1-7) は糖尿病性神経障害性疼痛を抑制する2017
- Author(s)
  小潟佳輝、根本亙、中川西修、丹野孝一
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール（長崎県、長崎市）
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-26460101
[Presentation] 嗅球摘出マウスの認知機能障害に対するアリピプラゾールの効果2017
- Author(s)
  髙橋浩平，中川西修，根本亙，小平貴代，荒井裕一朗，久光正，丹野孝一
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール（長崎県長崎市）
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-26460102
[Presentation] 嗅球摘出マウスのうつ様行動に対するメマンチンの効果2017
- Author(s)
  髙橋浩平，中川西修，根本亙，小平貴代，丹野孝一
- Organizer
  日本薬学会第137年会
- Place of Presentation
  東北大学川内キャンパス(宮城県仙台市）
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-26460102
[Presentation] 脊髄Angiotensin系は糖尿病性神経障害性疼痛の治療標的になり得るか？2017
- Author(s)
  根本　亙，小潟佳輝，山縣涼太，中川西　修，八百板富紀枝，丹野孝一
- Organizer
  平成29年度東北医科薬科大学創薬研究センターシンポジウム
- Data Source
  KAKENHI-PROJECT-17K08313
[Presentation] アンジオテンシンⅢ誘発性侵害刺激行動に対するアンジオテンシン (1-7) の抑制作用について2017
- Author(s)
  根本亙、中川西修、丹野孝一
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール（長崎県、長崎市）
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-26460101
[Presentation] 嗅球摘出マウスのうつ様行動に対するAngiotensin変換酵素阻害薬Captoprilの効果2017
- Author(s)
  小野涼太郎，中川西修，小平貴代，佐久間若菜，根本亙，丹野孝一
- Organizer
  第26回神経行動薬理若手研究者の集い
- Place of Presentation
  福岡大学メディカルホール（福岡県福岡市）
- Data Source
  KAKENHI-PROJECT-26460102
[Presentation] 脊髄疼痛伝達機構におけるアンジオテンシンⅡの役割2016
- Author(s)
  根本亙、小潟佳輝、丹野孝一
- Organizer
  生体機能と創薬シンポジウム2016
- Place of Presentation
  東北大学川内キャンパス（宮城県、仙台市）
- Year and Date
  2016-08-25
- Invited
- Data Source
  KAKENHI-PROJECT-26460101
[Presentation] 1型糖尿病モデルマウスの機械的アロディニアにおける脊髄内アンジオテンシンⅡ系の関与2016
- Author(s)
  山縣涼太、根本亙、小潟佳輝、中川西修、八百板富紀枝、丹野孝一
- Organizer
  生体機能と創薬シンポジウム2016
- Place of Presentation
  東北大学川内キャンパス（宮城県、仙台市）
- Year and Date
  2016-08-25
- Data Source
  KAKENHI-PROJECT-26460101
[Presentation] 更年期障害モデルマウスのうつ状態に対する新規選択的エストロゲン受容体モジュレターBE360の効果2016
- Author(s)
  佐久間若菜，中川西修，根本亙，八百板富紀枝，小川卓巳，太田公規，遠藤泰之，丹野孝一
- Organizer
  生体機能と創薬シンポジウム2016
- Place of Presentation
  東北大学川内キャンパス（宮城県仙台市）
- Year and Date
  2016-08-25
- Data Source
  KAKENHI-PROJECT-26460102
[Presentation] スカブロニンG-メチルエステルの認知障害改善作用とその機序について2016
- Author(s)
  小平貴代，中川西修，林嘉蓉，根本亙，佐久間若菜，小原祐太郎，小早川優，中田雅久，丹野孝一
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2016
- Place of Presentation
  東北大学川内キャンパス（宮城県仙台市）
- Data Source
  KAKENHI-PROJECT-26460102
[Presentation] 嗅球摘出マウスにおける線条体Dopamine受容体機能変化とそれに及ぼす抗うつ薬の影響2016
- Author(s)
  髙橋浩平，中川西修，根本亙，菊地恵理，佐久間若菜，小平貴代，丹野孝一
- Organizer
  第67回日本薬理学会北部会
- Place of Presentation
  北海道大学学術交流会館（北海道札幌市）
- Data Source
  KAKENHI-PROJECT-26460102
[Presentation] 更年期障害モデルマウスのうつ状態に対する新規選択的エストロゲン受容体モジュレターBE360の効果2016
- Author(s)
  佐久間若菜，中川西修，根本亙，八百板富紀枝，小川卓巳，太田公規，遠藤泰之，丹野孝一
- Organizer
  生体機能と創薬シンポジウム2016
- Place of Presentation
  東北大学川内北キャンパス(仙台）
- Year and Date
  2016-08-25
- Data Source
  KAKENHI-PROJECT-26460151
[Presentation] うつ病モデルマウスの脳内ドパミン神経機能変化について2016
- Author(s)
  中川西修，髙橋浩平，根本亙，菊地恵理，佐久間若菜，小平貴代，八百板富紀枝，荒井裕一朗，只野武，丹野孝一
- Organizer
  第20回活性アミンに関するワークショップ
- Place of Presentation
  ホテルマークワンつくば研究学園（茨城県つくば市）
- Data Source
  KAKENHI-PROJECT-26460102
[Presentation] The effects of liver hydrolysate on physical fatigue and sickness behavior2015
- Author(s)
  Kotaro Yamada, Osamu Nakagawasai, Wataru Nemoto, Hidetomo Sakurai, Koichi Tan-No
- Organizer
  12th Asian Congress of Nutrition
- Place of Presentation
  パシフィコ横浜 (神奈川県横浜市)
- Year and Date
  2015-05-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460102
[Presentation] 脊髄疼痛伝達機構におけるアンジオテンシンIIIの役割2015
- Author(s)
  根本　亙、小潟佳輝、中川西　修、八百板　富紀枝、只野　武、丹野孝一
- Organizer
  第66回日本薬理学会北部会
- Place of Presentation
  富山国際会議場（富山県富山市）
- Year and Date
  2015-09-18
- Data Source
  KAKENHI-PROJECT-26460101
[Presentation] Scabronine G-methylester attenuates hippocampal neurogenesis impairment and the memory deficits induced by olfactory bulbectomy2015
- Author(s)
  Jia Rong Lin, Osamu Nakagawasai, Wataru Nemoto, Yutaro Obara, Fukie Yaoita, Yu Kobayakawa, Masahisa Nakada, Koichi Tan-No
- Organizer
  第24回神経行動薬理若手研究者の集い
- Place of Presentation
  名古屋、愛知県
- Year and Date
  2015-03-17
- Data Source
  KAKENHI-PROJECT-26460102
[Presentation] 有痛性糖尿病性神経障害における脊髄アンジオテンシンIIの関与2015
- Author(s)
  小潟佳輝、根本　亙、中川西　修、八百板　富紀枝、只野　武、丹野孝一
- Organizer
  生体機能と創薬シンポジウム2015
- Place of Presentation
  日本大学薬学部（千葉県船橋市）
- Year and Date
  2015-08-27
- Data Source
  KAKENHI-PROJECT-26460101
[Presentation] 有痛性糖尿病性ニューロパチーにおける脊髄アンジオテンシン系の関与2015
- Author(s)
  小潟佳輝、根本　亙、中川西　修、八百板　富紀枝、只野　武、丹野孝一
- Organizer
  第66回日本薬理学会北部会
- Place of Presentation
  富山国際会議場（富山県富山市）
- Year and Date
  2015-09-18
- Data Source
  KAKENHI-PROJECT-26460101
[Presentation] 糖尿病誘発性アロディニアに対する脊髄アンジオテンシン系の関与2015
- Author(s)
  小潟佳輝、根本亙、中川西修、八百板富紀枝、只野武、丹野孝一
- Organizer
  第24回神経行動薬理若手研究者の集い
- Place of Presentation
  名城大学名駅サテライト(愛知県、名古屋市）
- Year and Date
  2015-03-17
- Data Source
  KAKENHI-PROJECT-26460101
[Presentation] NMDA受容体遮断薬MK-801誘発性記憶障害に対する緑茶成分テアニンの改善効果2014
- Author(s)
  宮昂平、中川西修、根本亙、八百板富紀枝、丹野孝一
- Organizer
  宮城薬剤師学術フォーラム2014
- Place of Presentation
  仙台、宮城県
- Year and Date
  2014-11-30
- Data Source
  KAKENHI-PROJECT-26460102
[Presentation] 胎生期メチルアゾキシメタノール処理マウスが神経発達障害仮説に基づいた統合失調症モデルに成り得るか？2014
- Author(s)
  中川西修、手塚大介、根本亙、八百板富紀枝、荒井裕一朗、只野武、丹野孝一
- Organizer
  第18回活性アミンに関するワークショップ
- Place of Presentation
  高松、香川県
- Year and Date
  2014-08-30
- Data Source
  KAKENHI-PROJECT-26460102
[Presentation] ロサルタンの抗侵害刺激作用について2014
- Author(s)
  根本亙、小潟佳輝、中川西修、八百板富紀枝、只野武、丹野孝一
- Organizer
  第126回日本薬理学会近畿部会
- Place of Presentation
  和歌山県JAビル（和歌山県、和歌山市）
- Year and Date
  2014-10-24
- Data Source
  KAKENHI-PROJECT-26460101
[Presentation] 嗅球摘出マウスの短期記憶障害と海馬神経新生抑制に対する新規選択的エストロゲン受容体モジュレーターBE360の改善効果2014
- Author(s)
  川西修、佐々木俊裕、斎藤智恵、深澤鈴、星杏奈、根本亙、八百板富紀枝、小川卓巳、太田公規、遠藤泰之、丹野孝一
- Organizer
  平成26年度東北薬科大学創薬研究センターシンポジウム
- Place of Presentation
  仙台
- Year and Date
  2014-06-14
- Data Source
  KAKENHI-PROJECT-26460151
[Presentation] Gangliosides produce nociceptive behavior and hyperalgesia via glutamate signals2013
- Author(s)
  Watanabe S., Tan-No K., Tadano T., HigashiH
- Organizer
  International Symposium for Neurosciences201
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-21600012
[Presentation] 脊髄疼痛伝達機構におけるアンジオテンシンII の役割について2013
- Author(s)
  根本亙,中川西修,八百板富紀枝,三浦圭裕,長谷川大地,大友光平,大堀彩,岡本駿,只野武,丹野孝一
- Organizer
  平成 25 年度東北薬科大学創薬研究センターシンポジウム
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-21600012
[Presentation] Angiotensin II induces nociceptive behavior accompanied by p38 MAPK phosphorylation mediated through spinal AT1 receptors2013
- Author(s)
  Nemoto W., Nakagawasai O., Yaoita F., Kanno S., Yomogida S., Ishikawa M., TadanoT., Tan-No K
- Organizer
  International Symposium for Neurosciences2013
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-21600012
[Presentation] Angiotensin II induces nociceptive behavior accompanied by p38 MAPK phosphorylation mediated through spinal AT1 receptors2013
- Author(s)
  Nemoto W, Nakagawasai O, Yaoita F, KannoS, Yomogida S, Ishikawa M, Tadano T, Tan-NoK
- Organizer
  International Symposium for Neurosciences2013
- Place of Presentation
  仙台
- Year and Date
  2013-02-26
- Data Source
  KAKENHI-PROJECT-22600010
[Presentation] アンジオテンシン II 誘発性疼痛関連行動における p38 MAPK の関与2012
- Author(s)
  根本亙、中川西修、八百板富紀枝、菅野秀一、蓬田伸、石川正明、只野武、丹野孝一
- Organizer
  第63回日本薬理学会北部会
- Place of Presentation
  新潟
- Year and Date
  2012-09-14
- Data Source
  KAKENHI-PROJECT-22600010
[Presentation] アンジオテンシン II 誘発性疼痛関連行動における p38 MAPK の関与2012
- Author(s)
  根本亙,中川西修,八百板富紀枝,菅野秀一,蓬田伸,石川正明,只野武,丹野孝一
- Organizer
  第63回日本薬理学会北部会
- Place of Presentation
  新潟
- Data Source
  KAKENHI-PROJECT-21600012
[Presentation] Involvement of the p53 tumor-suppressor protein in the development of antinociceptive tolrrance to morphine2011
- Author(s)
  Koichi Tan-No
- Organizer
  Italian-Japanese International Seminar for Neurosciences
- Place of Presentation
  Sendai
- Year and Date
  2011-09-01
- Data Source
  KAKENHI-PROJECT-21600012
[Presentation] モルヒネ鎮痛耐性および身体的依存形成メカニズムの解明2011
- Author(s)
  丹野孝一
- Organizer
  第428回集談会
- Place of Presentation
  仙台(東北薬科大学)
- Year and Date
  2011-10-31
- Data Source
  KAKENHI-PROJECT-22600010
[Presentation] Involvement of the p53 tumor-suppressor protein in the development of antinociceptive tolerance to morphin2011
- Author(s)
  Tan-No K., Shimoda M., Watanabe K., Nakagawasai O., Yaoita F., Kanno S., Ishikawa M., Bakalkin G., Tadano T
- Organizer
  Italian-Japanese International Seminar for Neurosciences
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-21600012
[Presentation] アンジオテンシンII脊髄クモ膜下腔内投与による ERK の活性化を介した疼痛関連行動2010
- Author(s)
  鈴木義紀、丹野孝一,中川西修,新島富紀枝、菅野秀一、蓬田伸、石川正明、只野武
- Organizer
  第61回日本薬理学会北部会
- Place of Presentation
  札幌
- Year and Date
  2010-09-10
- Data Source
  KAKENHI-PROJECT-22600010
[Presentation] アンジオテンシンII脊髄クモ膜下腔内投与による疼痛関連行動2010
- Author(s)
  鈴木義紀、丹野孝一、中川西修、新島富紀枝、菅野秀一、蓬田伸、石川正明、只野武
- Organizer
  第49回日本薬学会東北支部大会
- Place of Presentation
  郡山
- Year and Date
  2010-10-24
- Data Source
  KAKENHI-PROJECT-22600010
[Presentation] Intraplantar injection of gangliosides produces nociceptive behavior and hyperalgesia2010
- Author(s)
  Watanabe S., Tan-No K., Tadano T., Higashi H
- Organizer
  Molecular Targets for Novel Pain Therapeutics. From Basic Research to Clinical Translation
- Place of Presentation
  Calabria (Italy)
- Data Source
  KAKENHI-PROJECT-21600012
[Presentation] アンジオテンシンII脊髄クモ膜下腔内投与によるERKの活性化を介した疼痛関連行動2010
- Author(s)
  鈴木義紀, 丹野孝一, 中川西修, 他5名
- Organizer
  第61回日本薬理学会北部会
- Place of Presentation
  札幌
- Year and Date
  2010-09-10
- Data Source
  KAKENHI-PROJECT-22600010
[Presentation] アンジオテンシンII脊髄クモ膜下腔内投与による疼痛関連行動2010
- Author(s)
  鈴木義紀,丹野孝一,中川西修,新島富紀枝,菅野秀一,蓬田伸,石川正明,只野武
- Organizer
  第49回日本薬学会東北支部大会
- Place of Presentation
  郡山
- Data Source
  KAKENHI-PROJECT-21600012
[Presentation] アンジオテンシンII脊髄クモ膜下腔内投与による疾痛関連行動2010
- Author(s)
  鈴木義紀, 丹野孝一, 中川西修, 他5名
- Organizer
  第49回日本薬学会東北支部大会
- Place of Presentation
  郡山
- Year and Date
  2010-10-24
- Data Source
  KAKENHI-PROJECT-22600010
[Presentation] モルヒネ鎮痛耐性軽減薬の探索研究-慢性疼痛患者の QOL 向上を目指して-2009
- Author(s)
  丹野孝一,下田将司,中川西修,新島富紀枝,菅野秀一,石川正明,只野武
- Organizer
  第37回薬物活性シンポジウム
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-21600012
[Presentation] モルヒネ鎮痛耐性軽減薬の探索研究-慢性疼痛患者のQOL向上を目指して-2009
- Author(s)
  丹野孝一
- Organizer
  第37回薬物活性シンポジウム
- Place of Presentation
  東北薬科大学(仙台)
- Year and Date
  2009-10-09
- Data Source
  KAKENHI-PROJECT-21600012
[Presentation] ダイノルフィンA足蹠内投与による痛覚過敏作用のメカニズム2008
- Author(s)
  菅原麻衣、丹野孝一、中川西修、新島富紀枝、只野武
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18613016
[Presentation] Intrathecal N-ethylmaleimide, a cysteine protease inhibitor, produces nociceptive behavior through inhibition of dynorphin degradation.2008
- Author(s)
  Koichi Tan-No
- Organizer
  XI Workshop on Apoptosis in Biology and Medicine
- Place of Presentation
  Sendai
- Year and Date
  2008-09-14
- Data Source
  KAKENHI-PROJECT-18613016
[Presentation] モルヒネの身体的依存に及ぼすシステインプロテアーゼ阻害薬の抑制効果2008
- Author(s)
  佐藤丞、丹野孝一、下田将司、中川西修、新島富紀枝、只野武
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18613016
[Presentation] Intrathecal N-ethylmaleimide, a cysteine protease inhibitor, produces nociceptive behavior through inhibition of dynorphin degradation2008
- Author(s)
  Tan-No, K., Takahashi, H., Nakagawasai, O., Niijima, F., Sakurada, S., Bakalkin, G., Terenius, L., Tadano, T
- Organizer
  XI Workshop on Apoptosis in Biology and Medicine, Sendai
- Place of Presentation
  Japan
- Data Source
  KAKENHI-PROJECT-18613016
[Presentation] モルヒネ鎮痛耐性形成におけるシステインプロテアーゼの役割2007
- Author(s)
  丹野孝一、下田将司、中川西修、新島富紀枝、只野武
- Organizer
  第2回東北薬科大学ハイテク・リサーチシンポジウム
- Place of Presentation
  仙台
- Year and Date
  2007-05-25
- Data Source
  KAKENHI-PROJECT-18613016
[Presentation] 脊髄疼痛伝達機構におけるNMDA受容体グリシン調節部位の役割2007
- Author(s)
  江刺晶央、丹野孝一、中川西修、新島富紀枝、只野武
- Organizer
  第46回日本薬学会東北支部大会
- Place of Presentation
  仙台
- Year and Date
  2007-10-28
- Data Source
  KAKENHI-PROJECT-18613016
[Presentation] プロポリスの一酸化窒素産生抑制による抗炎症作用2007
- Author(s)
  菅原麻衣、丹野孝一、中川西修、新島富紀枝、吉田真、中畑則道、只野武
- Organizer
  第80回日本薬理学会年会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-18613016
[Presentation] モルヒネの身体的依存に及ぼす各種プロテアーゼ阻害薬の影響2007
- Author(s)
  佐藤丞、丹野孝一、下田将司、中川西修、新島富紀枝、只野武
- Organizer
  第58回日本薬理学会北部会
- Place of Presentation
  札幌
- Year and Date
  2007-09-29
- Data Source
  KAKENHI-PROJECT-18613016
[Presentation] モルヒネの身体的依存形成に及ぼす各種プロチアーゼ阻害薬の影響2007
- Author(s)
  丹野孝一
- Organizer
  第58回日本薬理学会北部会
- Place of Presentation
  北海道大学学術交流会館
- Year and Date
  2007-09-29
- Data Source
  KAKENHI-PROJECT-18613016
[Presentation] モルヒネ鎮痛耐性形成におけるシステインプロテアーゼの役割2007
- Author(s)
  丹野孝一
- Organizer
  第2回東北薬科大学ハイテク・リサーチシンポジウム
- Place of Presentation
  東北薬科大学
- Year and Date
  2007-05-25
- Data Source
  KAKENHI-PROJECT-18613016
[Presentation] ホルマリン誘発性侵害行動に対するダイノルフィンA足蹠内投与の二相性効果2007
- Author(s)
  菅原麻衣、丹野孝一、中川西修、新島富紀枝、只野武
- Organizer
  第58回日本薬理学会北部会
- Place of Presentation
  札幌
- Year and Date
  2007-09-29
- Data Source
  KAKENHI-PROJECT-18613016
[Presentation] システインプロテアーゼ阻害薬によるモルヒネ鎮痛耐性形成の抑制効果2007
- Author(s)
  下田将司、丹野孝一、中川西修、新島富紀枝、只野武
- Organizer
  第80回日本薬理学会年会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-18613016
[Presentation] モルヒネ鎮痛耐性形成に及ぼすプロテアーゼ阻害薬の影響2007
- Author(s)
  下田将司、丹野孝一、中川西修、新島富紀枝、只野武
- Organizer
  第16回神経行動薬理若手研究者の集い
- Place of Presentation
  名古屋
- Year and Date
  2007-03-13
- Data Source
  KAKENHI-PROJECT-18613016
[Presentation] ビッグダイノルフィン誘発性疼痛関連行動 : 脊髄一酸化窒素の関与2006
- Author(s)
  丹野孝一、高橋宏彰、中川西修、新島富紀枝、只野武
- Organizer
  第1回東北薬科大学ハイテク・リサーチシンポジウム
- Place of Presentation
  仙台
- Year and Date
  2006-05-26
- Data Source
  KAKENHI-PROJECT-18613016
[Presentation] モルヒネ鎮痛耐性に及ぼすシステインプロテアーゼ阻害薬の抑制効果2006
- Author(s)
  下田将司、丹野孝一、中川西修、新島富紀枝、只野武
- Organizer
  第57回日本薬理学会北部会
- Place of Presentation
  弘前
- Data Source
  KAKENHI-PROJECT-18613016
[Presentation] Differential effects of N-peptidyl-O-acyl hydroxylamines on dynorphin-induced antinociception in the mouse capsaicin test2006
- Author(s)
  Tan-No, K., Taira, A., Shimoda, M., Nakagawasai, O., Niijima, F., Demuth, H.-U., Silberring, J., Terenius, L., Tadano, T
- Organizer
  29th European Peptide Symposium
- Place of Presentation
  Gdansk, Poland
- Data Source
  KAKENHI-PROJECT-18613016
[Presentation] Angiotensin II type 1 receptor-mediated increase in spinal p38 MAPK phosphorylation leads to the induction of nociceptive behavior in mice
- Author(s)
  Osamu Nakagawasai, Wataru Nemoto, Yoshiki Ogata, Fukie Yaoita, Takeshi Tadano, Koichi Tan-No
- Organizer
  International Narcotics Research Conference 2014
- Place of Presentation
  Montreal, Canada
- Year and Date
  2014-07-13 – 2014-07-18
- Data Source
  KAKENHI-PROJECT-26460102
[Presentation] Role of the spinal angiotensin system in nociceptive transmission.
- Author(s)
  Wataru Nemoto, Osamu Nakagawasai, Fukie Yaoita, Koichi Tan-No
- Organizer
  生体機能と創薬シンポジウム2014
- Place of Presentation
  近畿大学東大阪キャンパス（大阪府、東大阪市）
- Year and Date
  2014-08-28 – 2014-08-29
- Invited
- Data Source
  KAKENHI-PROJECT-26460101
[Presentation] 疼痛伝達機構における脊髄アンジオテンシン系の役割
- Author(s)
  根本亙、小潟佳輝、中川西修、八百板富紀枝、只野武、丹野孝一
- Organizer
  第16回応用薬理シンポジウム
- Place of Presentation
  ホテル松島大観荘(宮城県、宮城郡松島町）
- Year and Date
  2014-12-05 – 2014-12-06
- Data Source
  KAKENHI-PROJECT-26460101
[Presentation] Antagonistic effect of angiotensin (1-7) on angiotensin II-induced nociceptive behavior in mice.
- Author(s)
  Wataru Nemoto, Yoshiki Ogata, Osamu Nakagawasai, Fukie Yaoita, Takeshi Tadanoa, Koichi Tan-No
- Organizer
  International Narcotics Research Conference 2014
- Place of Presentation
  Montreal (Canada)
- Year and Date
  2014-07-13 – 2014-07-18
- Data Source
  KAKENHI-PROJECT-26460101
[Presentation] Angiotensin II type 1 receptor-mediated increase in spinal p38 MAPK phosphorylation leads to the induction of nociceptive behavior in mice.
- Author(s)
  Osamu Nakagawasai, Wataru Nemoto, Yoshiki Ogata, Fukie Yaoita, Takeshi Tadanoa, Koichi Tan-No
- Organizer
  International Narcotics Research Conference 2014
- Place of Presentation
  Montreal (Canada)
- Year and Date
  2014-07-13 – 2014-07-18
- Data Source
  KAKENHI-PROJECT-26460101
[Presentation] ストレプトゾトシン誘発糖尿病性神経障害性疼痛における脊髄アンジオテンシン系の関与
- Author(s)
  小潟佳輝、根本亙、中川西修、八百板富紀枝、只野武、丹野孝一
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場(愛知県、名古屋市）
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-26460101
[Presentation] メチルアゾキシメタノールを用いた統合失調症モデルマウスの作製
- Author(s)
  中川西修、手塚大介、根本亙、八百板富紀枝、只野武、丹野孝一
- Organizer
  第16回応用薬理シンポジウム
- Place of Presentation
  松島、宮城県
- Year and Date
  2014-12-05 – 2014-12-06
- Invited
- Data Source
  KAKENHI-PROJECT-26460102
[Presentation] ロサルタンの脊髄クモ膜下腔内投与による抗侵害刺激作用について
- Author(s)
  根本亙、小潟佳輝、中川西修、八百板富紀枝、只野武、丹野孝一
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場(愛知県、名古屋市）
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-26460101
[Presentation] 糖尿病性神経障害性疼痛における脊髄アンジオテンシンIIの関与
- Author(s)
  小潟佳輝、根本亙、中川西修、八百板富紀枝、只野武、丹野孝一
- Organizer
  第65回日本薬理学会北部会
- Place of Presentation
  コラッセふくしま（福島県、福島市）
- Year and Date
  2014-09-26 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26460101
[Presentation] 1型糖尿病モデルマウスの神経障害性疼痛に対する脊髄アンジオテンシン系の関与
- Author(s)
  根本亙、小潟佳輝、中川西修、八百板富紀枝、只野武、丹野孝一
- Organizer
  日本薬学会第135年会
- Place of Presentation
  デザイン・クリエイティブセンター神戸(兵庫県、神戸市）
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26460101

1. NAKAGAWASAI Osamu (50296018)

# of Collaborated Projects: 6 results

# of Collaborated Products: 68 results
2. 根本亙 (80635136)

# of Collaborated Projects: 5 results

# of Collaborated Products: 70 results
3. OBARA Yutarou (40400270)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. ENDO Yasuyuki (80126002)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
5. 小野木弘志 (50610200)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 猪股浩平 (60221785)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 太田公規 (90347906)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
8. 合谷木徹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tan-no Koichi 丹野 孝一

TAN-NO Koichi 丹野 孝一

Research Projects

Research Products

Co-Researchers

脊髄アンジオテンシン系は難治性疼痛に対する新規治療標的になり得るか？Principal Investigator

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脊髄内TNF-α変換酵素による細胞外領域シェディングを介した疼痛制御機構

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Elucidation of neuropathic pain associated with type 2 diabetes mellitus: Involvement of spinal angiotensin system and development of the novel therapeutic agentsPrincipal Investigator

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Elucidation of the mechanism underlying diabetic neuropathic pain and development of its new therapy: Examination from the viewpoint of spinal angiotensin systemPrincipal Investigator

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Elucidation of the role of spinal angiotensin system in chronic pain: Aim at developing the new therapyPrincipal Investigator

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Development of hippocampal neurogenesis-promoting drugs as a target for the treatment and prevention of psychiatric disorders

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A New Development of Molecular Design Utilizing Novel Hydrophobic Structures

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The role of angiotensin II in nociceptive transmission in the spinal cord

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Elucidation of the mechanism underlying the suppression of the development of analgesic tolerance to morphine under chronic painPrincipal Investigator

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Elucidation of chronic pain mechanism from interactions between spinaI dynorphin system and p53, a transcription factorPrincipal Investigator

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The study of behavioral pharmacology, cellular and molecular biology on big dynorphin-induced painful paresthesia.Principal Investigator

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Pharmacological Study of Substance P and Dynorphin on the Spinal Regulation of Nociceptive InformationPrincipal Investigator

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[Book] オピオイド研究の進歩と展望2004

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Tan-no Koichi 丹野孝一

TAN-NO Koichi 丹野孝一