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SHINMOTO Michie  新本 美智枝

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SHINMOTO Micie  新本 美智枝

SHIMMOTO Michie  新本 美智枝

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Researcher Number 20216237
External Links
Affiliation (based on the past Project Information) *help 2016 – 2017: 公益財団法人東京都医学総合研究所, ゲノム医科学研究分野, 研究員
2014: 公益財団法人東京都医学総合研究所, ゲノム医科学研究分野, 研究員
2008: 財団法人東京都医学研究機構, 東京都臨床医学総合研究所, 研究員
2000 – 2002: 財団法人東京都医学研究機構, 東京都臨床医学総合研究所, 研究員
1999 – 2000: 財団法人 東京都医学研究機構, 東京都臨床医学総合研究所, 研究員 … More
1998: The Tokyo Metropolitan Institute of Medical Science, Clinical Genetics Researche, 臨床遺伝学研究部門, 研究員
1998: The Tokyo Metropolitan Institute of Medical Science, Department of Clinical Gene, 臨床遺伝学研究部門, 研究員
1997: (財)東京都臨床医学総合研究所, 臨床遺伝学研究部門, 研究員
1996: 財団法人 東京都臨床医学総合研究所, 臨床遺伝学研究部門, 研究員
1994 – 1996: 財団法人東京都臨床医学総合研究所, 臨床遺伝学研究部門, 研究員
1994: (財)東京都臨床医学総合研究所, 臨床遺伝学研究部門, 研究員
1993: 臨床遺伝学研究部門, 研究員
1993: 財団法人 東京都臨床医学総合研究所, 臨床遺伝学研究部門, 研究員 Less
Review Section/Research Field
Principal Investigator
Human genetics / Genome biology
Except Principal Investigator
応用薬理学・医療系薬学 / Pediatrics / Molecular biology / Functional biochemistry
Keywords
Principal Investigator
galactosialidosis / phospholipid transfer protein / gene overlap / protective protein / カルボキシペプチダーゼ / ガラクトシアリドーシス / グアニン4重鎖DMA / 多量体化 / G4結合ドメイン / FANCJ … More / DHX36 / 天然変性タンパク質ドメイン / 染色体高次構造多量体化 / 染色体高次構造 / HEATドメイン / Rif1 / グアニン4重鎖 / β-ガラクトシダーゼ / 保護タンパク / ノイラミニダーゼ / beta-ガラクトシダーゼ / 保護蛋白 … More
Except Principal Investigator
保護蛋白質 / ガラクトシアリドーシス / ファブリー病 / α-ガラクトシダーゼ / リソソーム / Lysosome / α-Galactosidase / 酵素補充療法 / Fabry disease / Cdc7キナーゼ / 複製タイミング / 複製起点 / アンチセンスオリゴDNA / リソソーム酵素 / 多機能性蛋白 / サポシン / Enzyme Replacement / Fadry Disease / α-ガラクトシターゼ / Enzyme replacement / GM2 activator / GM2 gangliosidosis / galactosialidosis / protective protein / alpha-galactosidase / SSCP / 遺伝子解析 / バキュロウイルス / トランスジェニックマウス / 遺伝子変異 / X線結晶構造解析 / メタノール資化酵母 / GM2活性化蛋白質 / GM2ガングリオシドーシス / 構造解析 / 染色体ダイナミクス / リン酸化 / 染色体DNA複製 / 脳発生 / 細胞分裂 / 乗り越えDNA合成 / 減数分裂期組換え / チェックポイント / 染色体DNA複製開始 / MCMタンパク質 / チェックポイント制御 / DNAヘリカーゼ / DNA複製 / 細胞周期 / 遺伝子の情報発現と複製 / エンドセリン1 / カルボキシペプチダーゼ / バイオセンサー / 保護蛋白質欠損症 / β-ガラクトシダーゼ / 遺伝子重複 / リン脂質転送蛋白質 / エンドセリン / デアミダーゼ / エステラーゼ / 酸性カルボキシペプチダーゼ / シアリダーゼ / beta-ガラクトシダーゼ Less
  • Research Projects

    (14 results)
  • Research Products

    (6 results)
  • Co-Researchers

    (17 People)
  •  グアニン4重鎖(G4)結合蛋白質を用いた機能的G4構造探索・制御技術の開発Principal Investigator

    • Principal Investigator
      新本 美智枝
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Genome biology
    • Research Institution
      Tokyo Metropolitan Institute of Medical Science
  •  Studies on the functions and structures of Cdc7 kinase, essential for initiation of DNA replication

    • Principal Investigator
      MASAI Hisao
    • Project Period (FY)
      2011 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Molecular biology
    • Research Institution
      Tokyo Metropolitan Institute of Medical Science
  •  Elucidation of DNA replication program in mammalian cells

    • Principal Investigator
      MASAI Hisao
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Functional biochemistry
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  Enzyme Replacement Therapy for Fabry Disease :Production of Efficient α-Galactosidase

    • Principal Investigator
      KASE Ryoichi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  Studies of the enzyme replacement therapy for Fabry disease

    • Principal Investigator
      KASE Ryoichi
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  リソソーム酵素のプロセシング及び分解制御機構とその遺伝病の分子機構の解明

    • Principal Investigator
      桜庭 均
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  Partial Overlaping between Protective Protein and Phospholipid Transfer Protein GenesPrincipal Investigator

    • Principal Investigator
      SHIMMOTO Michie
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C).
    • Research Field
      Human genetics
    • Research Institution
      The Tokyo Metropolitan Institute of Medical Science
  •  リソソーム酵素のプロセシング及び分解制御機構とその遺伝病の分子病態の解明

    • Principal Investigator
      桜庭 均
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  Structural analysis and molecular designing of enzyme proteins : Its application to clarification of pathology of inherited metabolic diseases and development of therapy

    • Principal Investigator
      SAKURABA Hitoshi
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      The Tokyo Metropolitan Institute of Medical Science
  •  多機能性蛋白による糖鎖分解酵素の制御機構とその欠損症の分子病理

    • Principal Investigator
      桜庭 均
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  多機能性蛋白による糖鎖分解酵素の制御機構とその欠損症の分子病理

    • Principal Investigator
      桜庭 均
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  ガラクトシアリドーシスの臨床像と保護蛋白の多機能性に関する研究;変異保護蛋白の性質と細胞内動態Principal Investigator

    • Principal Investigator
      新本 美智枝
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Human genetics
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  多機能性蛋白による糖鎖分解酵素の制御機構とその欠損症の分子病理

    • Principal Investigator
      SAKURABA Hitoshi
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  ガラクトシアリドーシスモデル動物作成のための基礎的研究:マウス保護蛋白ゲノムDNAのクローニングPrincipal Investigator

    • Principal Investigator
      新本 美智枝
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Human genetics
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research

All 2009 2008

All Journal Article Presentation

  • [Journal Article] Interactions between Swi1-Swi3, Mrc1 and S phase kinase, Hsk1 may regulate cellular responses to stalled replication forks in fission yeast2009

    • Author(s)
      Shimmoto, M., Matsumoto, S., Odagiri, Y., Noguchi, E., Russell, P., Masai, H.
    • Journal Title

      Genes to Cells (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18207009
  • [Journal Article] Interactions between Swi1-Swi3, Mrc1 and S phase kinase, Hsk1 may regulate cellular responses to stalled replication forks in fission yeast.2009

    • Author(s)
      Shimmoto, S., Matsumoto, S., Hayano, M., Yokoyama, M., Noguchi, E., Russell, P. and Masai, H
    • Journal Title

      Genes to Cells in press

      Pages: 0-0

    • Data Source
      KAKENHI-PROJECT-18207009
  • [Presentation] Regulation of replication fork in maintenance of genomic integrity2008

    • Author(s)
      Hisao Masai, Motoshi Hayano, Seiji Matsumoto, Yutaka Kanoh, Michie Shimmoto, Mika Yokoyama, Taku Tanaka, Naoko Kakusho, Naoko Yoshizawa-Sugata, You Zhiying, Sayuri Ito, Chika Taniyama, Ai Ishii
    • Organizer
      6th 3R Symposium
    • Place of Presentation
      Tsumagoi, Shizuoka
    • Data Source
      KAKENHI-PROJECT-18207009
  • [Presentation] Regula tion of replication fork integrity during S phase.2008

    • Author(s)
      Hisao Masai, Motoshi Hayano, Seiji Matsumoto, Yutaka Kanoh, Mika Yokoyama, Michie Shinmoto, Naoko Kakusho, Naoko Yoshizawa and Taku Tanaka
    • Organizer
      BMB2008
    • Place of Presentation
      神戸ポートアイランド
    • Data Source
      KAKENHI-PROJECT-18207009
  • [Presentation] Regulation of replication fork integrity during S phase2008

    • Author(s)
      Hisao Masai, Motoshi Hayano, Seiji Matsumoto, Yutaka Kanoh, Mika Yokoyama, Michiyo Shimmoto, Naoko Kakusho, Naoko Yoshizawa, Taku Tanaka
    • Organizer
      BMB (Biochemistry and Molecular Biology) 2008
    • Place of Presentation
      神戸ポートアイランド(シンポジウム)
    • Data Source
      KAKENHI-PROJECT-18207009
  • [Presentation] Regulation of establishment and maintenance of replication fork by Cdc7 kinase2008

    • Author(s)
      Hisao Masai, Motoshi Hayano, Seiji Matsumoto, Naoko Kakusho, Michiyo Shimmoto, Mika Yokoyama, Yutaka Kanoh, Taku Tanaka, Yukari Odagiri
    • Organizer
      Ataxia-Telangiectasia Workshop
    • Place of Presentation
      Ohtsu Prince Hotel at Lake Biwa
    • Data Source
      KAKENHI-PROJECT-18207009
  • 1.  SAKURABA Hitoshi (60114493)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 2.  ITOH Kohji (00184656)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 3.  KASE Ryoichi (20150203)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  MIYATAKE Syouitirou (30239420)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  MASAI Hisao (40229349)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 6 results
  • 6.  YOSHIZAWA Naoko (30344071)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  TAKAI Yuko (90332270)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 8.  MATSUMOTO Seiji (40190532)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 6 results
  • 9.  MORIYAMA Kenji (00250217)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  ISHII Ai (80124436)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 11.  TANAKA Taku (80425686)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  KANO Yutaka (90450593)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  ODA Masako (50399474)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  ITO Sayuri (60462777)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  HAYANO Motoshi (30593644)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  KAKUSHO Naoko (30599593)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  須賀田 直子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results

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