TAKASAKI Tomohiko 高崎智彦

… Alternative Names

高崎智彦タカサキトモヒコ

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Researcher Number	20221351
Other IDs
Affiliation (based on the past Project Information) *help	2013 – 2015: 国立感染症研究所, その他部局等, その他 2010 – 2015: 国立感染症研究所, ウイルス第一部, 室長 2012: 国立感染症研究所, ウイルス第一部室長 2012: 国立感染症研究所, その他部局等, 室長 2007: 国立感染症研究所, ウイルス1部, 室長 … More 1998: 国立感染症研究, ウイルス第一部, 主任研究官 1998: National Institute of Infectious Diseases・Department of virology I, Senior Scien, ウイルス第一部, 主任研究官 1996 – 1997: 近畿大学, 医学部, 講師 Less
Review Section/Research Field	Principal Investigator Virology Except Principal Investigator Virology / Virology / Hygiene
Keywords	Principal Investigator 霊長類モデル / 蚊媒介性ウイルス / 輸入感染症 / C型レクチン / ウイルス遺伝子 / 免疫不全マウス / 肝機能障害 / 関節炎 / マーモセット / チクングニアウイルス … More Except Principal Investigator … More デングウイルス / Japanese encephalitis virus / Dengue virus / デンブウイルス / 日本脳炎ウイルス / マーモセット / デング出血熱 / 免疫学 / ウイルス / Cytotoxic T lymphocyte / Vaccine / Flavivirus / エピトープ / デンフウウルス / キラーT細胞 / ワクチン / フラビウイルス / Dengue hemorrhagic fever / T lymphocyte / T細胞 / 脳神経 / 微生物 / 基礎医学 / 感染防御・制御 / 動物モデル / 個体 / デング熱 / 感染症 / 感染防護 / 感染防御 / 中和抗体 / cross-presentation / CTL / 組換えワクチン / 成分ワクチン / E蛋白質 / ウエストナイルウイルス Less

Establishment of marmoset model for elucidation of the pathogenesis of dengue hemorrhagic fever and development of new treatment
- Principal Investigator
  
  Kurane Ichiro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  National Institute of Infectious Diseases
The pathogenesis of flaviviral encephalitis bases on the immunological
- Principal Investigator
  
  KURANE ICHIRO
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Virology
- Research Institution
  National Institute of Infectious Diseases
Primate model and pathological analysis for Chikungunya virus infectionPrincipal Investigator
- Principal Investigator
  
  TAKASAKI Tomohiko
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  National Institute of Infectious Diseases
Elucidation of the pathogenesis of dengue fever and dengue hemorrhagic fever based on viral and immunological analysis
- Principal Investigator
  
  KURANE Ichiro
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  National Institute of Infectious Diseases
Basic research for development of CTL-inducible vaccine against West Nile virus using recombinant E protein
- Principal Investigator
  
  MASAKI Hideyuki
- Project Period (FY)
  2007 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  Kinki University
Development of flavivirus-cross-reactive subunit vaccines
- Principal Investigator
  
  KURANE Ichiro
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  Virology
- Research Institution
  National Institute of Infectious Diseases
  Kinki University
Analysis of flavivirus-cross-reactive immune responses which contribute to the pathogenesis of dengue hemorrhagic fever
- Principal Investigator
  
  KURANE Ichiro
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  National Institute of Infectious Diseases
  Kinki University

All 2015 2014 2013 2012 2011 2010 Other

All Journal Article Presentation Book

[Book] チクングニア熱2015
- Author(s)
  中山絵里、高崎智彦
- Total Pages
  5
- Publisher
  近代出版
- Data Source
  KAKENHI-PROJECT-24590564
[Journal Article] Formation of infectious dengue virus-antibody immune complex in vivo in marmosets (Callithrix jacchus) after passive transfer of anti-dengue virus monoclonal antibodies and infection with dengue virus.2015
- Author(s)
  Moi, M.L., Ami, Y., Shirai, K., Lim, C.K., Suzaki, Y., Saito, Y., Kitaura, K., Saijo, M., Suzuki, R., Kurane, I. and Takasaki, T.
- Journal Title
  
  American Journal of Tropical Medicine and Hygiene
  
  Volume: 92(2) Pages: 370-376
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25293112
[Journal Article] Qualitative differences in brain-infiltrating T cells are associated with a fatal outcome in mice infected with Japanese encephalitis virus2014
- Author(s)
  Kenji Shirai, Daisuke Hayasaka, Kazutaka Kitaura, Tomohiko Takasaki, Kouichi Morita, Ryuji Suzuki and Ichiro Kurane
- Journal Title
  
  Archives of Virology
  
  Volume: In press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670223
[Journal Article] Demonstration of marmosets (Callithrix jacchus) as a non-human primate model for secondary dengue virus infection: high levels of viremia and serotype cross-reactive antibody responses consistent with secondary infection of humans2014
- Author(s)
  Moi, M.L., Takasaki, T., Omatsu, T., Nakamura, S., Katakai, Y., Ami, Y., Suzaki, Y., Saijo, M., Akari, H. and Kurane, I.
- Journal Title
  
  Journal of General Virology
  
  Volume: 95 Issue: 3 Pages: 591-600
- DOI
  10.1099/vir.0.060384-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25293112, KAKENHI-PROJECT-25670218
[Journal Article] Immune-Related Gene Expression Profile in Laboratory Common Marmosets Assessed by an Accurate Quantitative Real-Time PCR Using Selected Reference Genes.2013
- Author(s)
  Fujii Y
- Journal Title
  
  Pros ONE
  
  Volume: 8 Issue: 2 Pages: e56296-e56296
- DOI
  10.1371/journal.pone.0056296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380172, KAKENHI-PROJECT-22390093, KAKENHI-PROJECT-22500391, KAKENHI-PROJECT-24300155, KAKENHI-PROJECT-24593183, KAKENHI-PROJECT-24790454, KAKENHI-PLANNED-22133002
[Journal Article] Presence of viral genome in urine and development of hematuria and pathological changes in kidneys in common marmoset (Callithrix jacchus) after inoculation with dengue virus.2013
- Author(s)
  Moi, M.L., Omatsu, T., Hirayama, T., Nakamura, S., Katakai, Y., Yoshida, T., Saito, A., Tajima, S., Ito, M., Takasaki, T., Akari, H. and Kurane, I
- Journal Title
  
  Pathogens
  
  Volume: 2 Pages: 357-393
- Data Source
  KAKENHI-PROJECT-22390093
[Journal Article] A new method for quantitative analysis of the T cell receptor V region repertoires in healthy common marmosets by microplate hybridization assay.2012
- Author(s)
  Kitaura, K., Fujii, Y., Matsutani, T., Shirai, K., Suzuki, S., Takasaki, T., Shimada, S., Kametani, Y., Shiina, T., Takabayashi, S., Katoh, H., Ogasawara, K., Kurane, I. and Suzuki, R.
- Journal Title
  
  Journal of Imunological Methods.
  
  Volume: 384(1-2) Pages: 81-91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390093
[Journal Article] A new method for quantitative analysis of the T cell receptor V region repertoires in healthy common marmosets by microplate hybridization assay.2012
- Author(s)
  Kitaura K
- Journal Title
  
  J Immunol Methods
  
  Volume: 364 Issue: 1-2 Pages: 81-91
- DOI
  10.1016/j.jim.2012.07.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380172, KAKENHI-PROJECT-22390093, KAKENHI-PROJECT-22500391, KAKENHI-PROJECT-22791823, KAKENHI-PROJECT-24300155, KAKENHI-PROJECT-24593183, KAKENHI-PROJECT-24790454, KAKENHI-PLANNED-22133002
[Journal Article] Changes in hematological and serum biochemical parameters in common marmosets (Callithrix jacchus) after inoculation with dengue virus.2012
- Author(s)
  Omatsu, T., Moi, M.L., Takasaki, T., Nakamura, S., Katakai, Y., Tajima, S., Ito, M., Yoshida, T., Saito, A., Akari, H. and Kurane, I
- Journal Title
  
  Journal of Medical Primatology
  
  Volume: 41(5) Issue: 5 Pages: 289-296
- DOI
  10.1111/j.1600-0684.2012.00552.x
- Data Source
  KAKENHI-PROJECT-22390093
[Journal Article] Changes in hematological and serum biochemical parameters in common marmosets (Callithrix jacchus) after inoculation with dengue virus.2012
- Author(s)
  Omatsu, T., Moi, M.L., Takasaki, T., Nakamura, S., Katakai, Y., Tajim1’10-1’2a, S., Ito, M., Yoshida, T., Saito, A., Akari, H. and Kurane, I.
- Journal Title
  
  Journal of Medical Primatology.
  
  Volume: 41(5) Pages: 289-296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390093
[Journal Article] Increased positive selection pressure within the CDR regions of the T cell receptor β gene in New World monkeys2011
- Author(s)
  Matsutani T, Fujii Y, Kitaura K, Suzuki S, Tsuruta Y, Itoh T, Nishimoto N, Takasaki T, Kurane I, Suzuki R
- Journal Title
  
  Am J Primatol
  
  Volume: 73 Issue: 10 Pages: 1082-1092
- DOI
  10.1002/ajp.20976
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390299, KAKENHI-PROJECT-22390093, KAKENHI-PROJECT-22390370, KAKENHI-PROJECT-23659291
[Journal Article] Common marmoset (Callithrix jacchus) as a primate model of dengue virus infection: development of high levels of viremia and demonstration of protective immunity.2011
- Author(s)
  Omatsu, T., Moi, M.L., Hirayama., T., Takasaki, T., Nakamura, S., Tajima, S., Ito, M., Yoshida, T., Saito, A., Katakai, Y., Akari, H. and Kurane, I
- Journal Title
  
  Journal of General Virology
  
  Volume: 92(Pt10) Issue: 10 Pages: 2272-2280
- DOI
  10.1099/vir.0.031229-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390093, KAKENHI-PROJECT-23790515
[Journal Article] Common marmoset (Callithrix jacchus) as a primate model of dengue virus infection : development of high levels of viraemia and demonstration of protective immunity2011
- Author(s)
  Omatsu T, Moi ML, Hirayama T, Takasaki T, Nakamura S, Tajima S, Ito M, Yoshida T, Saito A, Katakai Y, Akari H, Kurane I
- Journal Title
  
  J Gen Virol
  
  Volume: 92(Pt10) Pages: 2272-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390093
[Journal Article] Comprehensive analysis and characterization of the TCR alpha chain sequences in the common marmoset.2010
- Author(s)
  Fujii Y, Matsutani T, Kitaura K, Suzuki S, Itoh T, Takasaki T, Suzuki R, Kurane I.
- Journal Title
  
  Immunogenetics.
  
  Volume: 62(6) Pages: 383-395
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390093
[Journal Article] Comprehensive analysis and characterization of the TCR alpha chain sequences in the common marmoset2010
- Author(s)
  Fujii, K., Matsutani, T., Kitaura, K., Suzuki, S., Itoh, T., Takasaki, T., Suzuki, R. and Kurane, I
- Journal Title
  
  Immunogenetics
  
  Volume: 41(5) Issue: 6 Pages: 383-385
- DOI
  10.1007/s00251-010-0445-0
- Data Source
  KAKENHI-PROJECT-22390093
[Presentation] コモンマーモセットにおけるリアルタイムPCRを用いた免疫関連遺伝子発現解析2013
- Author(s)
  北浦一孝、藤井克樹、松谷隆治、白井顕治、鈴木さつき、高崎智彦、亀谷美恵、倉根一郎、鈴木隆二
- Organizer
  第60回日本実験動物学会総会
- Place of Presentation
  つくば
- Data Source
  KAKENHI-PROJECT-22390093
[Presentation] マーモセットを用いたチクングニアウイルス、デングウイルス感染病態解析2012
- Author(s)
  高崎智彦
- Organizer
  第60回日本ウイルス学会学術集会
- Place of Presentation
  大阪市
- Invited
- Data Source
  KAKENHI-PROJECT-24590564
[Presentation] コモンマーモセットにおけるTCRレパトア解析法の開発2012
- Author(s)
  北浦一孝、藤井克樹、松谷隆治、白井顕治、鈴木さつき、高崎智彦、倉根一郎、鈴木隆二
- Organizer
  第59回日本実験動物学会総会
- Place of Presentation
  別府
- Data Source
  KAKENHI-PROJECT-22390093
[Presentation] 新世界ザルにおけるT細胞受容体β鎖遺伝子のCDR3領域における正の選択2011
- Author(s)
  北浦一孝、松谷隆治、藤井克樹、白井顕治、鈴木さつき、高崎智彦、小笠原康悦、西本憲弘、倉根一郎、鈴木隆二
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22390093
[Presentation] チクングニア熱の輸入症例の報告および血清学的診断法の開発
- Author(s)
  中山絵里、小滝徹、谷ヶ崎和美、林昌宏、西條政幸、高崎智彦
- Organizer
  第６２回日本ウイルス学会学術集会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-10 – 2014-11-20
- Data Source
  KAKENHI-PROJECT-24590564
[Presentation] Role of antibodies in dengue protective immunity and infection during secondary infection of marmosets.
- Author(s)
  倉根一郎、モイ　メンリン、大松勉、高崎智彦、中村紳一朗、綱康至、片貝祐子、須崎百合子、明里宏文
- Organizer
  第60回日本ウイルス学会学術集会
- Place of Presentation
  大阪国際会議場
- Data Source
  KAKENHI-PROJECT-22390093

1. KURANE Ichiro (90278656)

# of Collaborated Projects: 6 results

# of Collaborated Products: 15 results
2. SUZUKI Ryuji (70373470)

# of Collaborated Projects: 4 results

# of Collaborated Products: 8 results
3. MATSUTANI Takaji (70372290)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
4. MASAKI Hideyuki (90247982)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. KONISHI Eiji (40135786)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. NAKAYAMA Eri (40645339)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. SATOH Mayumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KUWAHARA Miwa

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. ENNIS Franci

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 西本憲弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TAKASAKI Tomohiko 高崎 智彦

高崎 智彦 タカサキ トモヒコ

Research Projects

Research Products

Co-Researchers

Establishment of marmoset model for elucidation of the pathogenesis of dengue hemorrhagic fever and development of new treatment

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The pathogenesis of flaviviral encephalitis bases on the immunological

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Primate model and pathological analysis for Chikungunya virus infectionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of the pathogenesis of dengue fever and dengue hemorrhagic fever based on viral and immunological analysis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Basic research for development of CTL-inducible vaccine against West Nile virus using recombinant E protein

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of flavivirus-cross-reactive subunit vaccines

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of flavivirus-cross-reactive immune responses which contribute to the pathogenesis of dengue hemorrhagic fever

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] チクングニア熱2015

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Formation of infectious dengue virus-antibody immune complex in vivo in marmosets (Callithrix jacchus) after passive transfer of anti-dengue virus monoclonal antibodies and infection with dengue virus.2015

Author(s)

Journal Title

Data Source

[Journal Article] Qualitative differences in brain-infiltrating T cells are associated with a fatal outcome in mice infected with Japanese encephalitis virus2014

Author(s)

Journal Title

Data Source

[Journal Article] Demonstration of marmosets (Callithrix jacchus) as a non-human primate model for secondary dengue virus infection: high levels of viremia and serotype cross-reactive antibody responses consistent with secondary infection of humans2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Immune-Related Gene Expression Profile in Laboratory Common Marmosets Assessed by an Accurate Quantitative Real-Time PCR Using Selected Reference Genes.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Presence of viral genome in urine and development of hematuria and pathological changes in kidneys in common marmoset (Callithrix jacchus) after inoculation with dengue virus.2013

Author(s)

Journal Title

Data Source

[Journal Article] A new method for quantitative analysis of the T cell receptor V region repertoires in healthy common marmosets by microplate hybridization assay.2012

Author(s)

Journal Title

Data Source

[Journal Article] A new method for quantitative analysis of the T cell receptor V region repertoires in healthy common marmosets by microplate hybridization assay.2012

Author(s)

TAKASAKI Tomohiko 高崎智彦

高崎智彦タカサキトモヒコ