Miura Nobuhiko 三浦伸彦

… Alternative Names

MIURA Nobuhiko 三浦伸彦

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Researcher Number	20229644
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Affiliation (Current)	2025: 横浜薬科大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2020 – 2023: 横浜薬科大学, 薬学部, 教授 2017 – 2018: 独立行政法人労働者健康安全機構労働安全衛生総合研究所, 産業毒性・生体影響研究グループ, 部長代理 2016: 独立行政法人労働者健康安全機構労働安全衛生総合研究所, 産業毒性・生体影響研究グループ, 総括研究員 2016: 独立行政法人労働者健康安全機構労働安全衛生総合研究所, 産業毒性・生体影響研究グループ, 上席研究員 2015: 独立行政法人労働安全衛生総合研究所, 産業毒性・生体影響研究グループ, 統括研究員 … More 2010 – 2012: 独立行政法人労働安全衛生総合研究所, 健康障害予防研究グループ, 主任研究員 2002: 独立行政法人産業医学総合研究所, 健康障害予防研究部, 研究員 2001: National Institute of Industrial Health, Researcher, 研究員 2001: 独立行政法人産業医学研究総合所, 研究員 2001: 独立行政法人産業医学総合研究所, 研究員 2001: 独立行政法人産業医学総合研究所, 健康障害予防研究部, 研究員 1999 – 2001: Graduate School of Pharmaceutical Sciences, Tohoku University, Research Associate, 大学院・薬学研究科, 助手 1995 – 1998: 東北大学, 薬学部, 助手 Less
Review Section/Research Field	Principal Investigator Biological pharmacy / Medium-sized Section 58:Society medicine, nursing, and related fields / Risk sciences of radiation and chemicals / Hygiene / Public health/Health science Except Principal Investigator Public health/Health science / Biological Sciences / Risk sciences of radiation and chemicals / Environmental pharmacy / Biological pharmacy / 環境影響評価(含放射線生物学) / Science and Engineering
Keywords	Principal Investigator メタロチオネイン / ノックアウトマウス / 発現制御 / ディファレンシャルディスプレイ / 概日リズム / 気管支喘息 / 時間毒性 / TRPチャネル / 喘息モデル / 日内変動 … More / 衛生 / 肝障害 / 酸化チタン / トキシコロジー / 精巣毒性 / 二酸化チタンナノ粒子 / IVF法 / チタンナノ粒子 / 精子運動能 / 精巣機能 / ナノ粒子 / 二酸化チタン / バイオマーカー / 放射線 / エネルギー代謝 / 腎臓 / 肝臓 / DNAマイクロアレイ / カドミウム耐性細胞 / 耐性因子 / カドミウム … More Except Principal Investigator 酵母 / 耐性遺伝子 / シスプラチン / メタロチオネイン / Polymorphism / Cadmium / Metallothionein / カドミウム / Cdc34 / GFAT / 遺伝子多型 / Renal injury / Promoter / Kidney / Methylmercury / Resistance / Yeast / メチル水銀 / 耐性 / Ydr259c / Cin5 / パラコート / 転写因子 / ナノマテリアル / フローサイトメーター / 取り込み量 / ナノ粒子 / ナノ毒性 / 遺伝毒性 / Individual difference / High risk group / MTF1 / 腎毒性 / 個体差 / 高感受性集団 / Ubiquitin / グルコサミン / 培養細胞 / 細胞内標的分子 / メチル水銀毒性 / グルコサミン6リン酸 / ユビキチン / Exon 3 / PCR-SSCP / エクソン3 / プロモーター異常 / 塩基配列異常 / 腎臓 / 脳 / 遺伝子発現 / NM31 / 遺伝子欠損細胞 / ペンチレンテトラゾール / PTZ-17 / 痙攣 / Irradiation / Biodefense Factor / Screening / Environmental Pollutants / 防御遺伝子 / 放射線 / 生体防御遺伝子 / スクリーニング / 環境汚染物質 / 反応速度論的解析 / 酵素阻害活性 / 内分泌攪乱物質 / エストロゲン生合成 / 細胞生存率 / 連続測定 / ヒト培養細胞 / チトクロームP-450酵素活性 / 修飾作用 / EROD活性 / ダイオキシン / 毒性軽減 / チトクロームP-450 / 環境化学物質 / Yap1 / 発現抑制 / マイトマイシンC / 高発現 / ヒノキチオール / 亜鉛 / 遺伝子プロモーター / 合成誘導 Less

Chronobiological analysis of TRP channel for elucidation of asthma attackPrincipal Investigator
- Principal Investigator
  
  Miura Nobuhiko
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  Yokohama College of Pharmacy
Molecular mechanism of testicular dysfunction induced by titanium dioxide nanoparticlesPrincipal Investigator
- Principal Investigator
  
  Miura Nobuhiko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  National Institute of Occupational Safety and Health,Japan
Development of new method for risk assessment of nanomaterials by concurrent analysis of uptake potential and toxicity using flowcytometer
- Principal Investigator
  
  Toyooka Tatsushi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  National Institute of Occupational Safety and Health,Japan
Experimental verification for utilization of expression profiles of human metallothionein isoforms as a biomarker for X-ray irradiationPrincipal Investigator
- Principal Investigator
  
  MIURA Nobuhiko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  National Institute of Occupational Safety and Health, Japan
ダイオキシンの生体影響に対する化学物質の修飾効果の検討
- Principal Investigator
  
  MIYAIRI Shinichi
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Nihon University
シスプラチンの細胞毒性発現に関与する蛋白質の同定とその機能解析
- Principal Investigator
  
  永沼章
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
メタロチオネインによる発現制御を受ける遺伝子群の検索とその発現調節機構の解明Principal Investigator
- Principal Investigator
  
  三浦伸彦
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  National Institute of Occupational Safety and Health, Japan
Identification of a genetically high-risk group for cadmium toxicity
- Principal Investigator
  
  NAGANUMA Akira
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Environmental pharmacy
- Research Institution
  Tohoku University
シスプラチン耐性に関与するヒト細胞内因子の酵母を用いた検索
- Principal Investigator
  
  永沼章
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
Investigation of Target Molecules of Methylmercury Toxicity
- Principal Investigator
  
  NAGANUMA Akira
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Public health/Health science
- Research Institution
  Tohoku University
シスプラチン耐性に関与するヒト細胞内因子の酵母を用いた検索
- Principal Investigator
  
  永沼章
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Tohoku University
メタロチオネインの新しい生理機能としての遺伝子発現制御Principal Investigator
- Principal Investigator
  
  三浦伸彦
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tohoku University
Mechanism of Individual Difference in Metallothionein Concentration in the Kidney
- Principal Investigator
  
  MIYAIRI Shinichi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Public health/Health science
- Research Institution
  Tohoku University
Role of metallothionein in mechanism of onset of epileptic seizure
- Principal Investigator
  
  NAGANUMA Akira
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  TOHOKU UNIVERSITY
ヒノキチオールによるメタロチオネインの合成誘導と制癌剤の副作用軽減
- Principal Investigator
  
  NAGANUMA Akira
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
新しい重金属耐性因子の検索及び同定Principal Investigator
- Principal Investigator
  
  三浦伸彦
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Public health/Health science
- Research Institution
  Tohoku University
Screening of Biodefense Factors for Toxicity of Environmental Pollutants or Irradiation
- Principal Investigator
  
  NAGANUMA Akira
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  Tohoku University

All 2022 2021 2019 2018 2017 2016 2015 2011

All Journal Article Presentation

[Journal Article] Impairment of fertilization efficiency in mice following nano-sized titanium exposure2019
- Author(s)
  Nobuhiko Miura, Katsumi Ohtani, Tatsuya Hasegawa, Gi-Wook Hwang, Hiroki Yoshioka
- Journal Title
  
  Fund Toxicol Sci
  
  Volume: 6 Pages: 113-116
- NAID
  130007649489
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H02829
[Journal Article] Biphasic adverse effect of titanium nanoparticles on testicular function in mice2019
- Author(s)
  Nobuhiko Miura, Katsumi Ohtani, Tatsuya Hasegawa, Hiroki Yoshioka & Gi-Wook Hwang
- Journal Title
  
  Scientific Report
  
  Volume: 9 Issue: 1 Pages: 14373-14380
- DOI
  10.1038/s41598-019-50741-9
- Open Access
- Data Source
  KAKENHI-PROJECT-15H02829
[Journal Article] High sensitivity of testicular function to titanium nanoparticles2017
- Author(s)
  Nobuhiko Miura, Katsumi Ohtani, Tatsuya Hasegawa, Hiroki Yoshioka, Gi-Wook Hwang
- Journal Title
  
  The Journal of Toxicological Sciences
  
  Volume: 42 Issue: 3 Pages: 359-366
- DOI
  10.2131/jts.42.359
- NAID
  130006865652
- ISSN
  0388-1350, 1880-3989
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02829
[Journal Article] 労働環境におけるナノマテリアルの生体影響2016
- Author(s)
  三浦伸彦
- Journal Title
  
  環境技術
  
  Volume: 45 Pages: 26-31
- Data Source
  KAKENHI-PROJECT-15H02829
[Presentation] マウスTRPチャネル発現の日内変動　～呼吸器系統を中心に～2022
- Author(s)
  2)鎌田大暉，桂川真一，香川（田中）聡子，河村伊久雄, 吉岡弘毅，三浦伸彦
- Organizer
  第66回日本薬学会関東支部会
- Data Source
  KAKENHI-PROJECT-20K21733
[Presentation] マウスの呼吸器系統におけるTRPチャネル発現の日内変動2022
- Author(s)
  25)桂川真一，横田黎，宮澤正幸，香川（田中）聡子，河村伊久雄，横田理，吉岡弘毅，三浦伸彦
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20K21733
[Presentation] 肺気管支系におけるTRPチャネル発現の日内変動2021
- Author(s)
  18)桂川真一，照井楓香，宮澤正幸，香川（田中）聡子，河村伊久雄，横田理，吉岡弘毅，三浦伸彦
- Organizer
  第65回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-20K21733
[Presentation] Titanium dioxide nanopaticles-induced testicular dysfunction is mediated by anatase titanium dioxide2019
- Author(s)
  Hiroki Yoshioka, Nobuhiko Miura
- Organizer
  フォーラム2018 衛生薬学・環境トキシコロジー日韓次世代シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02829
[Presentation] 酸化チタンナノ粒子による急性精巣機能障害の誘発機構2019
- Author(s)
  三浦伸彦，田中廣輝，北條理恵子，大谷勝己，吉岡弘毅
- Organizer
  第45回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-15H02829
[Presentation] 労働衛生と精巣機能障害2018
- Author(s)
  三浦伸彦
- Organizer
  フォーラム2018 衛生薬学・環境トキシコロジー　シンポジウム「生殖毒性の最前線」
- Data Source
  KAKENHI-PROJECT-15H02829
[Presentation] 酸化チタンナノ粒子による精巣障害および肝障害の比較2017
- Author(s)
  三浦伸彦，北條理恵子，吉岡弘毅，大谷勝己
- Organizer
  生命科学系学会合同年次大会(ConBio2017)
- Data Source
  KAKENHI-PROJECT-15H02829
[Presentation] Titanium dioxide nanoparticle-induced testicular toxicity in mice2017
- Author(s)
  Nobuhiko Miura and Katsumi Ohtani
- Organizer
  The 56th Annual Meeting of Society of Toxicology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02829
[Presentation] 酸化チタンナノ粒子による精巣機能障害－肝障害との比較－2017
- Author(s)
  三浦伸彦，北條理恵子，大谷勝己
- Organizer
  フォーラム2017衛生薬学・環境トキシコロジー
- Data Source
  KAKENHI-PROJECT-15H02829
[Presentation] Titanium dioxide nanoparticle-induced testicular toxicity in mice2017
- Author(s)
  Miura N and Ohtani K
- Organizer
  Society of Toxicology
- Place of Presentation
  Baltimore
- Year and Date
  2017-03-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02829
[Presentation] 酸化チタンのマウス雄性生殖系への影響2017
- Author(s)
  大谷勝己，北條理恵子，三浦伸彦
- Organizer
  フォーラム2017衛生薬学・環境トキシコロジー
- Data Source
  KAKENHI-PROJECT-15H02829
[Presentation] マウスにおける酸化チタンの雄性生殖系への影響2017
- Author(s)
  大谷勝己，北條理恵子，吉岡弘毅，三浦伸彦
- Organizer
  生命科学系学会合同年次大会(ConBio2017)
- Data Source
  KAKENHI-PROJECT-15H02829
[Presentation] 二酸化チタンの結晶構造と精巣機能障害2016
- Author(s)
  三浦伸彦
- Organizer
  メタルバイオサイエンス研究会サテライト
- Place of Presentation
  静岡県立大学
- Year and Date
  2016-08-18
- Data Source
  KAKENHI-PROJECT-15H02829
[Presentation] 二要素(取込み量＋毒性)同時解析による新規ナノマテリアルリスク評価法の開発2016
- Author(s)
  豊岡達士，趙暁旭, 三浦信彦, 伊吹裕子，王瑞生
- Organizer
  日本毒性学会
- Place of Presentation
  名古屋
- Year and Date
  2016-06-29
- Data Source
  KAKENHI-PROJECT-15H06893
[Presentation] Adverse effect of titanium dioxide nanoparticle on testicular function in mice2016
- Author(s)
  Miura N, Ohtani　K
- Organizer
  Society of Toxicology
- Place of Presentation
  New Orleans
- Year and Date
  2016-03-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02829
[Presentation] 酸化チタンナノ粒子が精巣及び精子に与える影響解析2015
- Author(s)
  三浦伸彦，大谷勝己
- Organizer
  フォーラム2015衛生薬学・環境トキシコロジー
- Place of Presentation
  神戸学院大学
- Year and Date
  2015-09-17
- Data Source
  KAKENHI-PROJECT-15H02829
[Presentation] チタンナノ粒子による精巣機能障害の誘発2015
- Author(s)
  三浦伸彦，大谷勝己
- Organizer
  メタルバイオサイエンス研究会
- Place of Presentation
  名古屋国際センター
- Year and Date
  2015-08-28
- Data Source
  KAKENHI-PROJECT-15H02829
[Presentation] 放射線ばく露のバイオマーカーとしてのメタロチオネイン発現2011
- Author(s)
  三浦伸彦
- Organizer
  生体と金属・化学物質に関する研究会
- Data Source
  KAKENHI-PROJECT-22590571
[Presentation] 放射線ばく露のバイオマーカーとしてのメタロチオネイン発現2011
- Author(s)
  三浦伸彦
- Organizer
  「生体と金属・化学物質に関する研究会」30周年記念ミーティング
- Place of Presentation
  仙台市
- Year and Date
  2011-11-24
- Data Source
  KAKENHI-PROJECT-22590571

1. NAGANUMA Akira (80155952)

# of Collaborated Projects: 10 results

# of Collaborated Products: 0 results
2. FURUCHI Takemitsu (00302167)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
3. MIYAIRI Shinichi (50209855)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
4. NISHIYAMA Shoji

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. KUGE Shusuke (50186376)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. Toyooka Tatsushi (40423842)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. Wang Rui-sheng (10321895)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. Ibuki Yuko (30236781)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 宮澤智之 (30267116)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 木村真三 (50321849)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 大谷勝己 (50333373)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 吉岡弘毅 (30756606)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
13. 横田理 (70706605)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
14. OHTANI Katsumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 12 results

Miura Nobuhiko 三浦 伸彦

MIURA Nobuhiko 三浦 伸彦

Research Projects

Research Products

Co-Researchers

Chronobiological analysis of TRP channel for elucidation of asthma attackPrincipal Investigator

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Molecular mechanism of testicular dysfunction induced by titanium dioxide nanoparticlesPrincipal Investigator

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Experimental verification for utilization of expression profiles of human metallothionein isoforms as a biomarker for X-ray irradiationPrincipal Investigator

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メタロチオネインによる発現制御を受ける遺伝子群の検索とその発現調節機構の解明Principal Investigator

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メタロチオネインの新しい生理機能としての遺伝子発現制御Principal Investigator

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Principal Investigator

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Principal Investigator

Miura Nobuhiko 三浦伸彦

MIURA Nobuhiko 三浦伸彦

[Presentation] マウスTRPチャネル発現の日内変動　～呼吸器系統を中心に～2022