MUKAI TAKAO 向井孝夫

… Alternative Names

向井孝夫ムカイタカオ

MUKAI Takao 向井孝夫

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Researcher Number	20229917
Other IDs
External Links
Affiliation (Current)	2025: 北里大学, 獣医学部, 教授
Affiliation (based on the past Project Information) *help	2019 – 2023: 北里大学, 獣医学部, 教授 2007 – 2017: Kitasato University, 獣医学部, 教授 2005 – 2006: Kitasato University, 獣医畜産学部, 教授 2004: Kitasato University, School of Veterinary Medicine and Animal Sciences, Associate Professor, 獣医畜産学部, 助教授 1993 – 2003: 北里大学, 獣医畜産学部, 講師
Review Section/Research Field	Principal Investigator Zootechnical science/Grassland science / Zootechnical science/Grassland science / Basic Section 42010:Animal production science-related / Animal production science Except Principal Investigator Zootechnical science/Grassland science / 食品科学・栄養科学
Keywords	Principal Investigator プロバイオティクス / 付着 / 乳酸菌 / ムチン / ビフィズス菌 / Bifidobacterium / レクチン / 腸内細菌 / Lactobacillus / 感染予防 … More / Caco-2 / スルファターゼ / 硫酸化ムチン / 腸管バリア機能 / lactic acid bacteria / adhesion / 糖鎖 / キャンピロバクター / 感染 / ウイルス / Helicobacter pylori / 糖脂質 / 活性汚泥 / 凝集物質 / オリゴ糖 / sulfatase / シアリダーゼ / ミルクオリゴ糖 / Enterococcus gallinarum / 付着性 / 結合 / 硫酸化糖鎖 / 腸管バリア / 炎症 / 肥満 / anti-viral substances / bovine corona virus / bovine viral diarrhea virus / 腸管細胞 / コロナウイルス / 抗ウイルス物質 / ウシ粘膜病下痢ウイルス / induction / mucin / 抗菌ペプチド / サイトカイン / 腸管免疫 / 誘導 / gene / lectin / Bifidobafterium / 遺伝子 / 翻訳伸張因子 / 表層タンパク質 / フィブロネクチン / 抗ウイルス作用 / 抗菌作用 / 細胞接着 / クオラアムセンシング / ヘリコバクター / Campylobacter iejuni / Caco-2細胞 / 細胞付着 / レセプター / 凝集性細菌 / 畜産環境 / Bacillus / 廃水処理 … More Except Principal Investigator 肉牛 / 管理 / 物質循環 / 分子疫学 / コロナウイルス / 飼育管理 / 疫学 / ウシコロナウイルス / 腸管毒素原性大腸菌 / レクチン / 細胞付着 / 乳酸菌 / プロバイオティクス / レセプター / 糖脂質 / Caco-2 / 付着 / Lactobacillus Less

ビフィズス菌の腸内定着の確立におけるミルクオリゴ糖やムチン糖鎖代謝産物の役割Principal Investigator
- Principal Investigator
  
  向井孝夫
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42010:Animal production science-related
- Research Institution
  Kitasato University
Effects of sulfomucin-binding bifidobacteria on intestinal barrier function and analysis of gut colonization mechanismsPrincipal Investigator
- Principal Investigator
  
  MUKAI TAKAO
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42010:Animal production science-related
- Research Institution
  Kitasato University
Studies on prevention of obesity-induced low-grade inflammation through improving the profile of gut microbiota by potential probiotic which binds to sulfated sugar chainsPrincipal Investigator
- Principal Investigator
  
  Mukai Takao
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Animal production science
- Research Institution
  Kitasato University
Evaluation for the prevention of infection by lactic acid bacteria possessing the adhesion ability to mucinPrincipal Investigator
- Principal Investigator
  
  MUKAI Takao
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Zootechnical science/Grassland science
- Research Institution
  Kitasato University
Characterization of inhibitory factors of lactic acid bacteria against gastrointestinal pathogensPrincipal Investigator
- Principal Investigator
  
  MUKAI Takao
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Zootechnical science/Grassland science
- Research Institution
  Kitasato University
Studies on novel prevention mechanisms of infection by adhesive lactic acid bacteria to mucosal surface of intestinePrincipal Investigator
- Principal Investigator
  
  MUKAI Takao
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Zootechnical science/Grassland science
- Research Institution
  Kitasato University
Studies on induction of anti-viral substances by lactic acid bacteria adhering to mucosal surface of intestine.Principal Investigator
- Principal Investigator
  
  MUKAI Takao
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Zootechnical science/Grassland science
- Research Institution
  Kitasato University
物質循環型牧場における肉牛飼育管理法確立のためのウイルスの分子疫学
- Principal Investigator
  
  太田達郎
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Zootechnical science/Grassland science
- Research Institution
  Kitasato University
Induction of mucin gene expression by lactic acid bacteria adhering to intestinal epithelial cellsPrincipal Investigator
- Principal Investigator
  
  MUKAI Takao
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Zootechnical science/Grassland science
- Research Institution
  Kitasato University
Molecular analysis of adhesion protein produced by lactic acid bacteria including Bifidobacterium for probiotic applicationPrincipal Investigator
- Principal Investigator
  
  MUKAI Takao
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Zootechnical science/Grassland science
- Research Institution
  Kitasato University
感染予防へ向けたレクチン産生性ビフィズス菌の細胞接着機構の解明Principal Investigator
- Principal Investigator
  
  向井孝夫
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Zootechnical science/Grassland science
- Research Institution
  Kitasato University
感染防御を目的としたビフィズス菌の腸上皮細胞への接着機構の解明Principal Investigator
- Principal Investigator
  
  向井孝夫
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Zootechnical science/Grassland science
- Research Institution
  Kitasato University
レクチンを有する乳酸菌の細胞接着性と消化管系病原微生物に対する感染予防効果
- Principal Investigator
  
  大堀均
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  食品科学・栄養科学
- Research Institution
  Kitasato University
感染防御を目的とした腸内有用乳酸菌の上皮細胞の接着機構の解明Principal Investigator
- Principal Investigator
  
  向井孝夫
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Zootechnical science/Grassland science
- Research Institution
  Kitasato University
畜産排水処理に関わる微生物のフロック発現因子の解析Principal Investigator
- Principal Investigator
  
  向井孝夫
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Zootechnical science/Grassland science
- Research Institution
  Kitasato University
畜産排水処理に関わる微生物由来新規タンパク質の機能特性とその遺伝学的解析Principal Investigator
- Principal Investigator
  
  向井孝夫
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Zootechnical science/Grassland science
- Research Institution
  Kitasato University
畜産廃水処理に関わる微生物が生産する新規タンパク質の機能特性とその遺伝学的解析Principal Investigator
- Principal Investigator
  
  向井孝夫
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Zootechnical science/Grassland science
- Research Institution
  Kitasato University

[Book] ヨーグルトの辞典2016
- Author(s)
  向井孝夫
- Total Pages
  11
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-15K07709
[Book] Lactobacilusの腸粘膜への付着に関与する菌体表層糖質乳酸菌とビフィズス菌のサイエンス2010
- Author(s)
  向井孝夫
- Publisher
  京都大学学術出版会
- Data Source
  KAKENHI-PROJECT-21580334
[Book] 食の安全と予防医学(分担執筆)2009
- Author(s)
  向井孝夫
- Total Pages
  29
- Publisher
  養賢堂
- Data Source
  KAKENHI-PROJECT-21580334
[Book] 乳酸菌の上皮細胞や宿主受容体分子への付着性の評価食品機能性評価マニュアル集III2009
- Author(s)
  向井孝夫
- Publisher
  社団法人日本食品科学工学会
- Data Source
  KAKENHI-PROJECT-19580315
[Book] 微生物を用いた機能性評価 1)乳酸菌の上皮細胞や宿主受容体分子への付着性の評価食品機能性評価マニュアル集(第III集)2009
- Author(s)
  向井孝夫(分担)
- Publisher
  社団法人日本食品科学工学会(印刷中)
- Data Source
  KAKENHI-PROJECT-19580315
[Book] プロバイオティクスの家禽への利用卵の科学と機能2008
- Author(s)
  向井孝夫
- Publisher
  アイ・ケイコーポレーション
- Data Source
  KAKENHI-PROJECT-19580315
[Book] 最新畜産物利用学(斎藤、西村、松田編)2006
- Author(s)
  向井孝夫(分担)
- Publisher
  朝倉書店
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17580240
[Book] 農医連携の架け橋としてのプロバイオティクスの可能性を探る北里大学農医連携学術叢書第6号
- Author(s)
  向井孝夫
- Publisher
  養賢堂(印刷中)
- Data Source
  KAKENHI-PROJECT-19580315
[Journal Article] Genome sequence of Enterococcus gallinarum AH4, a milk oligosaccharide-degrading strain isolated from suckling rats2023
- Author(s)
  Yamamoto, Y., Suzuki, Y., Tsukuda, R., Asai, C., Ishizuka, M., Tsujikawa, Y., Sakane, I., Osawa, R. and Mukai, T.
- Journal Title
  
  Microbiol Resour Announc.
  
  Volume: 12 Issue: 10
- DOI
  10.1128/mra.00395-23
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K05974
[Journal Article] Sharing of Moonlighting Proteins Mediates the Symbiotic Relationship among Intestinal Commensals.2023
- Author(s)
  Nishiyama K, Yong CC, Moritoki N, Kitazawa H, Odamaki T, Xiao JZ, Mukai T.
- Journal Title
  
  Applied and environmental microbiology
  
  Volume: 89 Issue: 3
- DOI
  10.1128/aem.02190-22
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K05974
[Journal Article] O-acetylesterase activity of Bifidobacterium bifidum sialidase facilities the liberation of sialic acid and encourages the proliferation of sialic acid scavenging Bifidobacterium breve.2022
- Author(s)
  Yokoi T, Nishiyama K, Kushida Y, Uribayashi K, Kunihara T, Fujimoto R, Yamamoto Y, Ito M, Miki T, Haneda T, Mukai T, Okada N.
- Journal Title
  
  Environmental microbiology reports
  
  Volume: 14 Issue: 4 Pages: 637-645
- DOI
  10.1111/1758-2229.13083
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K05974, KAKENHI-PROJECT-22K07073, KAKENHI-PROJECT-19K07543, KAKENHI-PROJECT-21K05367
[Journal Article] Extracellular Vesicles Produced by Bifidobacterium longum Export Mucin-Binding Proteins2020
- Author(s)
  Nishiyama Keita、Takaki Takashi、Sugiyama Makoto、Fukuda Itsuko、Aiso Maho、Mukai Takao、Odamaki Toshitaka、Xiao Jin-zhong、Osawa Ro、Okada Nobuhiko
- Journal Title
  
  Applied and Environmental Microbiology
  
  Volume: 86 Issue: 19
- DOI
  10.1128/aem.01464-20
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07119, KAKENHI-PROJECT-19K06374, KAKENHI-PROJECT-19K15965, KAKENHI-PROJECT-20K15438
[Journal Article] ビフィズス菌と宿主腸粘膜との相互作用に関わる因子2018
- Author(s)
  西山啓太，向井孝夫
- Journal Title
  
  日本乳酸菌学会誌
  
  Volume: 29 Pages: 13-18
- NAID
  130007635161
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K07709
[Journal Article] Bifidobacterium bifidum, Extracellular Sialidase Enhances Adhesion to the Mucosal Surface and Supports Carbohydrate Assimilation2017
- Author(s)
  Nishiyama Keita、Yamamoto Yuji、Sugiyama Makoto、Takaki Takashi、Urashima Tadasu、Fukiya Satoru、Yokota Atsushi、Okada Nobuhiko、Mukai Takao
- Journal Title
  
  mBio
  
  Volume: 8 Issue: 5
- DOI
  10.1128/mbio.00928-17
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08003, KAKENHI-PROJECT-17K15249, KAKENHI-PROJECT-15K07709
[Journal Article] Lactobacillus rhamnosus GG SpaC pilin subunit binds to the carbohydrates moieties of intestinal glycoconjugates2016
- Author(s)
  Nishiyama K, Ueno S, Sugiyama M, Yamamoto Y, Mukai T.
- Journal Title
  
  Anim. Sci. J.
  
  Volume: 87 Issue: 6 Pages: 809-815
- DOI
  10.1111/asj.12491
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H06581, KAKENHI-PROJECT-15K07709
[Journal Article] Adhesion Properties of Lactic Acid Bacteria on Intestinal Mucin2016
- Author(s)
  Nishiyama K, Sugiyama M, Mukai T
- Journal Title
  
  Microorganisms
  
  Volume: 4 Issue: 3 Pages: 34-34
- DOI
  10.3390/microorganisms4030034
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H06581, KAKENHI-PROJECT-15K07709
[Journal Article] 乳酸菌の腸粘膜への定着機構2016
- Author(s)
  西山啓太，向井孝夫．
- Journal Title
  
  化学と生物
  
  Volume: 54 Pages: 471-477
- NAID
  130006772567
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K07709
[Journal Article] 乳酸菌とムチンの相互作用　－糖鎖を介した乳酸菌の腸粘膜への付着機構－2015
- Author(s)
  西山啓太，向井孝夫
- Journal Title
  
  応用糖質科学
  
  Volume: 5(1) Pages: 61-65
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24580397
[Journal Article] Evaluation of bifidobacterial adhesion to acidic sugar chains of porcine colonic mucins2014
- Author(s)
  Nishiyama K, Kawanabe A, Miyauchi H, Abe F, Tsubokawa D, Ishihara K, Yamamoto Y, Mukai T.
- Journal Title
  
  Biosci Biotechnol Biochem
  
  Volume: 78（8） Issue: 8 Pages: 1444-1451
- DOI
  10.1080/09168451.2014.918491
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24580397
[Journal Article] Lactobacillus gasseri SBT2055 reduces infection by and colonization of Campylobacter jejuni.2014
- Author(s)
  Nishiyama K, Seto Y, Yoshioka K, Kakuda T, Takai S, Yamamoto Y, Mukai T.
- Journal Title
  
  PLoS One
  
  Volume: 9(9) Issue: 9 Pages: e108827-e108827
- DOI
  10.1371/journal.pone.0108827
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24580397, KAKENHI-PROJECT-24580452
[Journal Article] シグナル配列非依存的に分泌される多機能タンパク質の役割と提示機構2013
- Author(s)
  西山啓太、山本裕司、向井孝夫
- Journal Title
  
  乳酸菌学会誌
  
  Volume: 24 Pages: 99-99
- NAID
  10031184596
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24580397
[Journal Article] Identification and characterization of sulfated carbohydrate-binding protein from Lactobacillus reuteri2013
- Author(s)
  Nishiyama K, Ochiai A, Tsubokawa D, Ishihara K, Yamamoto Y, Mukai T
- Journal Title
  
  PLoS ONE
  
  Volume: 8 Issue: 12 Pages: e83703-e83703
- DOI
  10.1371/journal.pone.0083703
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24580397
[Journal Article] Isolation of Potential Probiotic <i>Lactobacillus</i> <i>rhamnosus</i> Strains from Traditional Fermented Mare Milk Produced in Sumbawa Island of Indonesia2012
- Author(s)
  Shi T, Nishiyama K, Nakamata K, Aryantini NP, Mikumo D, Oda Y, Yamamoto Y, Mukai T, Sujaya IN, Urashima T, Fukuda K
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume: 76 Issue: 10 Pages: 1897-1903
- DOI
  10.1271/bbb.120385
- NAID
  130004054008
- ISSN
  0916-8451, 1347-6947
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24580397
[Journal Article] 生きた微生物を食べて人も動物も健康に～農学と医学領域から注目される乳酸菌2012
- Author(s)
  西山啓太、山本裕司、向井孝夫
- Journal Title
  
  ビオフィリア
  
  Volume: 8 Pages: 38-43
- Data Source
  KAKENHI-PROJECT-24580397
[Journal Article] 陽内細菌とプロバイオティクス2010
- Author(s)
  向井孝夫
- Journal Title
  
  東北のコロニー 34
  
  Pages: 13-20
- Data Source
  KAKENHI-PROJECT-21580334
[Journal Article] Lactobacillus乳酸菌におけるS-layer様タンパク質が介在する腸上皮への付着2008
- Author(s)
  向井孝夫
- Journal Title
  
  日本乳酸菌学会誌 19
  
  Pages: 21-29
- NAID
  10029751708
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19580315
[Journal Article] Lactobacillus乳酸菌におけるS-layer 様タンパク質が介在する腸上皮への付着2008
- Author(s)
  向井孝夫
- Journal Title
  
  日本乳酸菌学会誌 19(1)
  
  Pages: 21-29
- NAID
  10029751708
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19580315
[Journal Article] チーズの新規保健機能2008
- Author(s)
  向井孝夫
- Journal Title
  
  畜産の情報 8
  
  Pages: 58-67
- Data Source
  KAKENHI-PROJECT-19580315
[Journal Article] チーズの新規保健機能2008
- Author(s)
  向井孝夫
- Journal Title
  
  畜産の情報 226
  
  Pages: 58-67
- Data Source
  KAKENHI-PROJECT-19580315
[Journal Article] Propagation of bovine coronavirus in clones of Caco-2 cell line showing different levels of alkaline phosphatase activity2006
- Author(s)
  Mori K, Inoue Y, Mukai T, Ohori H.
- Journal Title
  
  Animal Sci J 77
  
  Pages: 253-257
- NAID
  10021222127
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17580240
[Journal Article] Propagation of bovine coronavirus in clones of Caco-2 cell line showing different levels of alkaline phosphatase activity2006
- Author(s)
  Mori K., Inoue Y., Mukai T., Ohori H.
- Journal Title
  
  Animal Sci J 77
  
  Pages: 253-257
- NAID
  10021222127
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17580240
[Journal Article] Binding of Bifidbacteriun bifidum and Lactobacillus reuteri to the carbohydrate moieties of intestinal glycolipids recognized by peanut agglutinim.2004
- Author(s)
  Mukai T et al.
- Journal Title
  
  Int.J.Food Microbiol. 90
  
  Pages: 357-362
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15580237
[Journal Article] Cell surface-associated proteinaceous substances of Bifidobacterium bifidum are involved in binding to the carbohydrate moieties of intestinal glycolipids recognized by peanut agglutinin.2004
- Author(s)
  Mukai, T., Kaneko, S., Hashizume, W., Ohori, H.
- Journal Title
  
  Int.J.Food Microbiol. 90
  
  Pages: 357-362
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15580237
[Journal Article] Molecular mechanism of adhesion of lactobacilli to mucosal surface.2003
- Author(s)
  Mukai, T., Toba, T., Ohori, H.
- Journal Title
  
  Milk Science(in Japanese) 52,3
  
  Pages: 167-174
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15580237
[Journal Article] Lactobacillus kitasatonis sp.nov., from chicken intestine.2003
- Author(s)
  Mukai, T., Arihara, K., Ikeada, A., Nomura, K., Suzuki, F., Ohori, H.
- Journal Title
  
  Int.J.Syst.Evol.Microbiol. 53
  
  Pages: 2055-2059
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15580237
[Patent] 抗ヘリコバクター・ハイルマニー剤2013
- Inventor(s)
  瀬戸泰幸、東直樹、向井孝夫、中村正彦、松井英
- Industrial Property Rights Holder
  瀬戸泰幸、東直樹、向井孝夫、中村正彦、松井英
- Industrial Property Rights Type
  特許
- Filing Date
  2013-12-20
- Data Source
  KAKENHI-PROJECT-24580397
[Presentation] 乳飲期ラットから分離されたEnterococcus gallinarum AH4株におけるミルクオリゴ糖代謝遺伝子の同定2023
- Author(s)
  山本裕司, 附田怜央, 高岡あゆ美, 田村奏瑛, 辻川勇治, 坂根巌, 鈴木康規, 大澤朗, 向井孝夫.
- Organizer
  第4回ビフィズス菌シンポジウム
- Data Source
  KAKENHI-PROJECT-22K05974
[Presentation] Bifidobacterium breveにおける硫酸化糖代謝関連遺伝子の同定2022
- Author(s)
  附田怜央、春日美咲、山本裕司、向井孝夫
- Organizer
  日本酪農科学会
- Data Source
  KAKENHI-PROJECT-22K05974
[Presentation] 高脂肪食給餌が腸内環境と炎症発症に及ぼす影響2018
- Author(s)
  向井孝夫，山本裕司
- Organizer
  北里大学私立大学研究ブランディングキックオフシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-15K07709
[Presentation] Bifidobacterium bifidumにおけるシアリダーゼは宿主との相互作用を促進し糖の資化をサポートする2017
- Author(s)
  西山啓太，山本裕司，杉山真言，篠原有香，浦島匡，吹谷智，横田篤，岡田信彦，向井孝夫
- Organizer
  日本農芸化学会2017年度大会
- Place of Presentation
  京都女子大学（京都府京都市）
- Year and Date
  2017-03-19
- Data Source
  KAKENHI-PROJECT-15K07709
[Presentation] プロバイオティクスによるカンピロバクターの鶏腸管への定着の阻害2017
- Author(s)
  向井孝夫
- Organizer
  平成28年度　日本獣医師会獣医学術学会年次学会
- Place of Presentation
  ホテル金沢（石川県金沢市）
- Year and Date
  2017-02-26
- Invited
- Data Source
  KAKENHI-PROJECT-15K07709
[Presentation] ビフィズス菌および乳酸菌が高脂肪摂取マウスの腸管バリア機能に及ぼす影響2016
- Author(s)
  本村祐樹，井上千佳，山本裕司，向井孝夫
- Organizer
  日本畜産学会第121回大会
- Place of Presentation
  日本獣医生命科学大学（東京都武蔵野市）
- Year and Date
  2016-03-29
- Data Source
  KAKENHI-PROJECT-15K07709
[Presentation] ヒト便由来Bifidobacterium longum subsp. longumのFimA線毛の多型がムチンへの付着性に及ぼす影響2016
- Author(s)
  鏡谷竹生，西山啓太，鈴木謙太，鈴木徹，大澤朗，山本裕司，向井孝夫
- Organizer
  日本乳酸菌学会2016年度大会
- Place of Presentation
  北里大学白金キャンパス（東京都港区）
- Year and Date
  2016-07-09
- Data Source
  KAKENHI-PROJECT-15K07709
[Presentation] Lactobacillus gasseri の aggregation-promoting factor は宿主への定着と Campylobacter jejuni の競合阻害に寄与する2016
- Author(s)
  西山啓太，瀬戸泰幸，岡田信彦，山本裕司，向井孝夫
- Organizer
  第20回腸内細菌学会
- Place of Presentation
  東京大学伊藤国際学術研究センター（東京都文京区）
- Year and Date
  2016-06-10
- Data Source
  KAKENHI-PROJECT-15K07709
[Presentation] ビフィズス菌由来シアリダーゼのムチン付着因子としての評価2014
- Author(s)
  西山啓太、吹谷智、横田篤、山本裕司、向井孝夫
- Organizer
  日本畜産学会第118回大会
- Place of Presentation
  つくば国際会議場(茨城県つくば市)
- Data Source
  KAKENHI-PROJECT-24580397
[Presentation] Lactobacillus reutriにおけるElongation factor Tuのシグナル非依存的な分泌機構に関する研究2014
- Author(s)
  西山啓太、南條早由利、遠藤紗耶、小菅晴春、山本裕司、向井孝夫
- Organizer
  日本農芸化学会2014年度大会
- Place of Presentation
  明治大学生田キャンパス（神奈川県川崎市）
- Data Source
  KAKENHI-PROJECT-24580397
[Presentation] フィブロネクチン付着性乳酸菌によるCampylobacterの感染予防への活用に向けた研究2013
- Author(s)
  西山啓太、瀬戸康幸、山本裕司、向井孝夫
- Organizer
  日本乳酸菌学会2013年度大会
- Place of Presentation
  北海道大学学術交流会館(北海道札幌市)
- Data Source
  KAKENHI-PROJECT-24580397
[Presentation] Binding of EF-Tu of Lactobacillus reuteri JCM1081 to porcine gastric mucin and mucosal surface of gastrointestinal tract2013
- Author(s)
  Nishiyama K, Kaneko H, Ochiai A, Tsubokawa D, Ishihara K, Yamamoto Y, Mukai T
- Organizer
  IDF World Dairy Summit 2013.
- Place of Presentation
  パンパシフィック横浜ベイホテル東急(神奈川県、横浜市）
- Data Source
  KAKENHI-PROJECT-24580397
[Presentation] Lactobacillus reuteri JCM1081のEF-Tuの硫酸化糖鎖に対する結合特性の評価2012
- Author(s)
  西山啓太、坪川大悟、中光貴之、山本裕司、市川尊文、五艘行信、石原和彦、向井孝夫
- Organizer
  日本畜産学会,第115回大会講演要旨
- Place of Presentation
  名古屋大学
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-21580334
[Presentation] Campylobacterと同一のレセプターに結合するLactobacillus gasseriによるin vivo感染阻害2011
- Author(s)
  西山啓太、角田勤、高井伸二、山本裕司、瀬戸泰幸、中島肇、向井孝夫
- Organizer
  日本畜産学会,第114回大会講演要旨
- Place of Presentation
  北里大学
- Year and Date
  2011-08-26
- Data Source
  KAKENHI-PROJECT-21580334
[Presentation] L. gasseri SBT2055のAggregation-promorting factorのフィブロネクチンの付着特性2011
- Author(s)
  西山啓太、中里彩季子、山本裕司、瀬戸泰行、中島肇、向井孝夫
- Organizer
  日本酪農科学学会60周年記念大会
- Place of Presentation
  フォレスト仙台
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-21580334
[Presentation] L.reuteriJCM1081の推定付着因子であるEF-TuのpH依存的な付着特性の変化2010
- Author(s)
  西山啓太、向井孝夫, ほか3名
- Organizer
  日本畜産学会
- Place of Presentation
  東京
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-21580334
[Presentation] Lactobacillus reuteri JCM1081のElongation Factor-Tuの胃腸粘膜への付着因子としての評価2010
- Author(s)
  西山啓太、浜野太一、金子仁美、山本裕司、向井孝夫
- Organizer
  日本乳酸菌学会2010年度大会
- Place of Presentation
  フォレスト仙台
- Year and Date
  2010-07-26
- Data Source
  KAKENHI-PROJECT-21580334
[Presentation] L.reuteri JCM1081のElongation Factor-Tuの胃腸粘膜への付着因子としての評価2010
- Author(s)
  西山啓太, 向井孝夫, 他2名
- Organizer
  日本乳酸菌学会
- Place of Presentation
  フォレスト仙台(仙台)
- Year and Date
  2010-07-26
- Data Source
  KAKENHI-PROJECT-21580334
[Presentation] L. reuteriの推定付着因子であるEF-TuのpH依存的な付着特性の変化2010
- Author(s)
  西山啓太、浜野太一、金子仁美、山本裕司、向井孝夫
- Organizer
  日本畜産学会,第112回大会講演要旨
- Place of Presentation
  明治大学
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-21580334
[Presentation] 乳酸菌を対象とした病原細菌のQuorum sensing 阻害物質の検索2009
- Author(s)
  小倉憂也ら, 中鉢弥伸, 山本裕司, 向井孝夫
- Organizer
  日本畜産学会第110回大会
- Place of Presentation
  藤沢
- Data Source
  KAKENHI-PROJECT-19580315
[Presentation] 農医連携の懸け橋としてのプロバイオティクスの可能性を探る2008
- Author(s)
  向井孝夫
- Organizer
  第6回北里大学農医連携シンポジウム
- Place of Presentation
  相模原
- Data Source
  KAKENHI-PROJECT-19580315
[Presentation] Lactobacillus乳酸菌におけるS-layer様タンパク質が介在する腸上皮への付着2007
- Author(s)
  向井孝夫
- Organizer
  2007年度日本乳酸菌学会秋季セミナー
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19580315
[Presentation] Typical signal sequence–independent export mechanism of elongation factor Tu in Lactobacillus reuteri
- Author(s)
  Keita Nishiyama, Yuji Yamamoto, Mukai Takao
- Organizer
  11th Symposium on Lactic Acid Bacteria
- Place of Presentation
  Egmond aan Zee, the Netherlands
- Year and Date
  2014-08-31 – 2014-09-04
- Data Source
  KAKENHI-PROJECT-24580397
[Presentation] 酸素耐性乳酸菌育種方法の検討
- Author(s)
  佐々木諒子、喜多隆文、三宅香名芽、山本裕司、向井孝夫
- Organizer
  日本農芸化学会2013年度大会
- Place of Presentation
  東北大学（仙台市）
- Data Source
  KAKENHI-PROJECT-24580397
[Presentation] Lactobacillus rhamnosus由来Spa線毛の糖鎖結合特性の解析
- Author(s)
  西山啓太, 山本裕司, 向井孝夫
- Organizer
  日本畜産学会第119回大会
- Place of Presentation
  宇都宮大学峰キャンパス(栃木県宇都宮市）
- Year and Date
  2015-03-28 – 2015-03-29
- Data Source
  KAKENHI-PROJECT-24580397
[Presentation] Lactobacillus rhamnosus 由来Mucus-binding factor の消化管粘液成分への付着における役割の評価
- Author(s)
  上野慎太郎, 西山啓太, 仲又幸一, Sujaya I. Nengah, 福田健二, 浦島匡, 山本裕司, 向井孝夫
- Organizer
  日本畜産学会第119回大会
- Place of Presentation
  宇都宮大学峰キャンパス(栃木県宇都宮市）
- Year and Date
  2015-03-28 – 2015-03-29
- Data Source
  KAKENHI-PROJECT-24580397
[Presentation] Aggregation-promoting factor 1 (APF1)のフィブロネクチン結合因子としての解析
- Author(s)
  西山啓太、遠藤沙織、中里彩季子、瀬戸康幸、中島肇、山本裕司、向井孝夫
- Organizer
  日本畜産学会第116回大会
- Place of Presentation
  安田女子大学（広島市）
- Data Source
  KAKENHI-PROJECT-24580397
[Presentation] Lactobacillus gasseri SBT2055由来aggregation-promoting factor1 (APF1)のフィブロネクチン結合特性の評価
- Author(s)
  西山啓太、遠藤沙織、中里彩季子、瀬戸康幸、中島肇、山本裕司、向井孝夫
- Organizer
  日本農芸化学会2013年度大会
- Place of Presentation
  東北大学（仙台市）
- Data Source
  KAKENHI-PROJECT-24580397
[Presentation] インドネシア・スンバワ島発酵馬乳由来Lactobacillus rhamnosusのInternalin Jの結合特性の解析
- Author(s)
  仲又幸一、西山啓太、石塔拉、ntini Niputudesy、Arya福田健二、Sujaya I Nengah、浦島匡、山本裕司、向井孝夫
- Organizer
  日本乳酸菌学会2012年度大会
- Place of Presentation
  つくば国際会議場（つくば市）
- Data Source
  KAKENHI-PROJECT-24580397

1. YAMAMOTO Yuji (10453507)

# of Collaborated Projects: 2 results

# of Collaborated Products: 18 results
2. 大堀均 (40004741)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. MATSUI Hidenori (30219373)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 太田達郎 (50050513)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KANEKO Hitomi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. KIMURA Makoto

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. HAMANO Taichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. NISHIYAMA Keita

# of Collaborated Projects: 1 results

# of Collaborated Products: 18 results
9. 浦島匡

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 岡田信彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MUKAI TAKAO 向井 孝夫

向井 孝夫 ムカイ タカオ

MUKAI Takao 向井 孝夫

Research Projects

Research Products

Co-Researchers

ビフィズス菌の腸内定着の確立におけるミルクオリゴ糖やムチン糖鎖代謝産物の役割Principal Investigator

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Review Section

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Effects of sulfomucin-binding bifidobacteria on intestinal barrier function and analysis of gut colonization mechanismsPrincipal Investigator

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Review Section

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Studies on prevention of obesity-induced low-grade inflammation through improving the profile of gut microbiota by potential probiotic which binds to sulfated sugar chainsPrincipal Investigator

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Evaluation for the prevention of infection by lactic acid bacteria possessing the adhesion ability to mucinPrincipal Investigator

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Characterization of inhibitory factors of lactic acid bacteria against gastrointestinal pathogensPrincipal Investigator

Principal Investigator

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Studies on novel prevention mechanisms of infection by adhesive lactic acid bacteria to mucosal surface of intestinePrincipal Investigator

Principal Investigator

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Studies on induction of anti-viral substances by lactic acid bacteria adhering to mucosal surface of intestine.Principal Investigator

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物質循環型牧場における肉牛飼育管理法確立のためのウイルスの分子疫学

Principal Investigator

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Induction of mucin gene expression by lactic acid bacteria adhering to intestinal epithelial cellsPrincipal Investigator

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Molecular analysis of adhesion protein produced by lactic acid bacteria including Bifidobacterium for probiotic applicationPrincipal Investigator

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感染予防へ向けたレクチン産生性ビフィズス菌の細胞接着機構の解明Principal Investigator

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感染防御を目的としたビフィズス菌の腸上皮細胞への接着機構の解明Principal Investigator

Principal Investigator

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レクチンを有する乳酸菌の細胞接着性と消化管系病原微生物に対する感染予防効果

Principal Investigator

MUKAI TAKAO 向井孝夫

向井孝夫ムカイタカオ

MUKAI Takao 向井孝夫

[Book] 微生物を用いた機能性評価 1)乳酸菌の上皮細胞や宿主受容体分子への付着性の評価食品機能性評価マニュアル集(第III集)2009

[Book] 農医連携の架け橋としてのプロバイオティクスの可能性を探る北里大学農医連携学術叢書第6号