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AONO Sachiko  青野 幸子

ORCIDConnect your ORCID iD *help
… Alternative Names

青野 幸子  アオノ サチコ

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Researcher Number 20231780
External Links
Affiliation (based on the past Project Information) *help 2011: 基礎生物学研究所, 神経生理学研究室, 特別協力研究員
2009 – 2010: Institute for Developmental Research, Aichi Human Service Center, 周生期学部, 主任研究員
2005 – 2007: 愛知県心身障害者コロニー発達障害研究所, 周生期学部, 主任研究員
1997 – 2001: 愛知県心身障害者コロニー発達障害研究所, 周生期学部, 主任研究員
1998: 愛知県心身障害者コロニー発達障害研究所, 周性期学部, 主任研究員 … More
1997: Aichi Prefectural Colony Chief.Researcher, 発達障害研究所・周生期, 主任研究員
1997: 愛知県コロニー, 発達障害研究所周生期, 主任研究員
1995: 愛知県心身障害者コロニー, 発達障害研究所・発達障害研究所・周生期学部, 研究員
1995: Institute for Developmental Research, Aichi prefectural colony, Department of Pe, 周生期学部, 研究員
1993: 主任研究員
1987 – 1988: 発達障害研究所, 周生期学部, 助手 Less
Review Section/Research Field
Principal Investigator
Nerve anatomy/Neuropathology / 内分泌・代謝学 / Applied pharmacology
Except Principal Investigator
Pediatrics / Neurology / 内分泌・代謝学 / Embryonic/Neonatal medicine
Keywords
Principal Investigator
TATA box / ノックアウトマウス / プロテオグリカン / コンドロイチン硫酸 / ニューログリカンC / Brain / Neural transmission / Neuronal circuit / Knockdown mice / Knockout mice … More / Proteoglycan / Chondroitin sulfate / Neuroglycan C / 脳 / 神経伝達 / 神経回路 / ノックダウンマウス / Crigler-Najjar syndrome / Hyperbilirubinemia / Bilirubin / Missense mutation / Bilirubin : UDP-glucuronosyltransferase / Choronic hyperbilirubinemia / Gilbert's syndrome / クリグラー・ナジャール症候群タイプII / ガンラット / クリグラー・ナジャール症候群タイプI / 優性遺伝 / ギルバ-ト症候群 / TATAbox / 変異 / UDPGT遺伝子 / 高ビリルビン血症 / ビリルビン / クリグラー・ナジャール症候群 / ミスセンス変異 / ビリルビン:UDP-グルクロン酸転位酵素 / 体質性黄疸 / ギルバート症候群 / プレイオトロフィン / ノックインマウス / 多動性症侯群 / 行動異常 / 脳タンパク / 多動性症候群 / メチルフェニデート / メタンフェタミン / 薬剤感受性 / 薬物依存 … More
Except Principal Investigator
ビリルビン / グルクロン酸転移酵素 / クリグラーナジャー症候群 / bilirubin / 新生児黄疸 / tin-protoporphyrin / hemeoxygenase / drugtherapy / cerebellar hypoplasia / neonatal-jaundice / プルキンエ細胞 / 錫プロトポルフィリン / ヘムオキシゲナーゼ / 動物モデル / ラジカル反応 / ヘムオキシゲナーゼ錫プロトポルフィリン / 薬物治療 / ビリルビン脳症 / Phosphorylation / Dendrite / Axon / Neuron / Brain / Chondroitin sulfate / Proteoglycan / Neuroglycan C / トランスジェニックマウス / パートタイムプロテオグリカン / ノックアウトマウス / site-directed mutagenesis / 発生工学 / 軸索 / 樹状突起 / 神経細胞 / リン酸化 / 神経回路形成 / 脳 / 相同組換え / 遺伝子 / コンドロイチン硫酸 / プロテオグリカン / ニューログリカンC / Gene expression / Liver / Baculovirus / Glucuronic acid / Bilirubin / Jaundice / Gene therapy / がんラット / 遺伝子発現 / 肝臓 / バキュロウイルス / グルクロン酸 / 黄疸 / 遺伝子治療 / Temperature-sensitive mutants / Guanylytransferase / Yeast / Capping / 遺伝子診断 / 光増感性 / ヘムオキシゲネース / EC 2.4.1.17 / gene / glucuronosylation / Gilbert's syndrome / Crigler Najjar type II / Crigler Najjar type I / jaundice / ラジカル / ポルフィリン / 遺伝子解析 / ガンラット / ジルベール症 / クリグラー・ナジャー症 Less
  • Research Projects

    (7 results)
  • Research Products

    (35 results)
  • Co-Researchers

    (10 People)
  •  Neuroglycan C, a chondroitin sulfate proteoglycan, overcomes the abnormal behavior induced by administration of some drugs?Principal Investigator

    • Principal Investigator
      AONO Sachiko
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied pharmacology
    • Research Institution
      National Institute for Basic Biology
      Institute for Developmental Research, Aichi Human Service Center
  •  Functions of Neuroglycan C, Which Specific to the Central Nervous System, and its Application to the Neural RegenerationPrincipal Investigator

    • Principal Investigator
      AONO Sachiko
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Nerve anatomy/Neuropathology
    • Research Institution
      Institute for Developmental Research, Aichi Human Service Center
  •  Studies on functions of NGC, a brain-specific proteoglycan, in the brain development by genetic engineering

    • Principal Investigator
      OOHIRA Atsuhiko
    • Project Period (FY)
      1998 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Institute for Development Research, Aichi Human Service Center
  •  The genetic inheritance of Gibert's syndromePrincipal Investigator

    • Principal Investigator
      AONO Sachiko
    • Project Period (FY)
      1997 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      内分泌・代謝学
    • Research Institution
      Institute for Develomental Research Aichi Human Service Center
  •  Gene therapy for Crigler-Najjar syndrome type l by using a model animal

    • Principal Investigator
      KOIWAI Osamu
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      内分泌・代謝学
    • Research Institution
      SCIENCE UNIVERSITY OF TOKYO,Faculty of Science & Technology
      Aichi Cancer Center Research Institute
  •  THE RESEARCH FOR DEVELOPMENT OF GENETHERAPY AND PORPHYRIN-THERAPY FORNEONATAL HYPERBILIRUBINEMIA

    • Principal Investigator
      KEINO Hiroomi
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Embryonic/Neonatal medicine
    • Research Institution
      Institute for Developmental Research, Aichi prefectural colony
  •  Neurochemical and histochemical studies on the mechanism and prevention of cerebellar under-development due to perinatal hyperbilirubinemia

    • Principal Investigator
      KEINO Hiroomi
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Institute for Developmental Research

All 2011 2010 2009 2007 2006 2005

All Journal Article Presentation Book

  • [Book] Neuroglycan C, a part-time proteoglycan, in the central nervous system, in Neural Proteoglycans(Maeda, N., ed.), pp.37-50.2007

    • Author(s)
      Aono, S.
    • Total Pages
      281
    • Publisher
      Research Signpost,Kerala
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17500246
  • [Book] Neural Proteoglycans(Maeda, N., ed.), pp.37-50., Research Signpost, Kerala2007

    • Author(s)
      Aono S.
    • Total Pages
      281
    • Publisher
      Neuroglycan C, a part-time proteoglycan, in the central nervous system
    • Data Source
      KAKENHI-PROJECT-17500246
  • [Book] Chondroitin Sulfate Proteoglycans in the Brain, in Advances in Pharmacology, Vol53, Chondroitin Sulfate : Structure, Role and Pharmacological Activity Advances in Pharmacology (Volpi N. ed.)2006

    • Author(s)
      Aono S.
    • Publisher
      Academic Press, San Diego
    • Data Source
      KAKENHI-PROJECT-17500246
  • [Book] Chondroitin Sulfate Proteoglycans in the Brain, in Advances in Pharmacology, Vol53, Chondroitin Sulfate:Structure, Role and Pharmacological Activity Advances in Pharmacology(Volpi N.ed.), pp324-336.2006

    • Author(s)
      Aono S.
    • Total Pages
      568
    • Publisher
      Academic Press,San Diego
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17500246
  • [Journal Article] Neuroglycan C, a brain-specific chondroitin sulfate proteoglycan, interacts with pleiotrophin, a heparin-binding growth factor2010

    • Author(s)
      Nakanishil, K., Tokita, Y., Aono, S., Ida, M., Matsui, F., HigashI, Y., and Oohira, A.
    • Journal Title

      Neurochem. Res

      Volume: 35 Pages: 1131-1137

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590606
  • [Journal Article] Neuroglycan C, a part time proteoglycan, in the central nervous system(Maeda, N., ed.)2007

    • Author(s)
      Aono S.
    • Journal Title

      Neural Proteoglycans

      Pages: 37-50

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500246
  • [Journal Article] Expression and identification of a new splice variant of neuroglycan C, a transmembrane chondroitin sulfate proteoglycan, in the human brain2006

    • Author(s)
      Aono S.
    • Journal Title

      Journal of Neuroscience Research 83

      Pages: 110-118

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500246
  • [Journal Article] Expression and identification of a new splice variant of neuroglycan C,a trans-membrane chondroitin sulfate proteoglycan,in the human brain.2006

    • Author(s)
      Aono S.
    • Journal Title

      Journal of Neuroscience Research 83

      Pages: 110-118

    • Data Source
      KAKENHI-PROJECT-17500246
  • [Journal Article] Identification of neurite outgrowth-promoting domains of neuroglycan C,a brainspecific chondroitin sulfate proteoglycan,and involvement of phosphatidylinositol 3-kinase and protein kinase C signaling pathways in neuritogenesis2006

    • Author(s)
      Nakanishi K.and Aono S.(equal contribution)
    • Journal Title

      Journal of Biological Chemistry 281

      Pages: 24970-24978

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17500246
  • [Journal Article] Chondroitin Sulfate Proteoglycans in the Brain(Volpi N. ed.)2006

    • Author(s)
      Aono S.
    • Journal Title

      Advances in Pharmacology, Chondroitin Sulfate : Structure, Role and Pharmacological Activity Advances in Pharmacology Vol.53

      Pages: 324-336

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500246
  • [Journal Article] Identification of neurite outglowth-promoting domains of neuroglycan C, a brain-specific chondroitin sulfate proteoglycan, and involvement of phosphatidylinositol 3-kinase and protein kinase C signaling pathways in neuritogenesis2006

    • Author(s)
      Nakanishi K. and Aono S. (equal contribution)
    • Journal Title

      Journal of Biological Chemistry 281

      Pages: 24970-24978

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500246
  • [Journal Article] Expression and identification of a new splice variant of neuroglycan C,a transmembrane chondroitin sulfate proteoglycan,in the human brain2006

    • Author(s)
      Aono S.
    • Journal Title

      Journal of Neuroscience Research 83

      Pages: 110-118

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17500246
  • [Journal Article] Identification of neurite outgrowth-promoting domains of neuroglycan C,a brain-specific chondroitin sulfate proteoglycan,and involvement of phosphatidylinositol 3-kinase and protein kinase C signaling pathways in neuritogenesis.2006

    • Author(s)
      Nakanishi K, Aono S.(equal contribution)
    • Journal Title

      Journal of Biological Chemistry 281

      Pages: 24970-24978

    • Data Source
      KAKENHI-PROJECT-17500246
  • [Presentation] ニューログリカンC-KOマウスの脳タンパクに対する向精神薬の影響2011

    • Author(s)
      青野幸子
    • Organizer
      第54回日本神経化学会
    • Place of Presentation
      瑠璃光(石川県)
    • Year and Date
      2011-09-26
    • Data Source
      KAKENHI-PROJECT-21590606
  • [Presentation] ニューログリカンC-KOマウスの脳タンパクに対する向精神薬の影響2011

    • Author(s)
      青野幸子
    • Organizer
      日本神経化学会
    • Place of Presentation
      瑠璃光(加賀市)
    • Year and Date
      2011-09-26
    • Data Source
      KAKENHI-PROJECT-21590606
  • [Presentation] Effect of psychotropic drugs on behavior of mice which show abnormal expressions of neuroglycan C, a brain-specific chondroitin sulfate proteoglycan2010

    • Author(s)
      青野幸子
    • Organizer
      Neuro2010
    • Place of Presentation
      神戸国際会議場(神戸)
    • Year and Date
      2010-09-04
    • Data Source
      KAKENHI-PROJECT-21590606
  • [Presentation] 脳に特異的に発現するニューログリカンCの遺伝子改変マウスに対する向精神薬の影響2010

    • Author(s)
      青野幸子
    • Organizer
      Neuro2010
    • Place of Presentation
      神戸コンベンションセンター(神戸市)
    • Year and Date
      2010-09-04
    • Data Source
      KAKENHI-PROJECT-21590606
  • [Presentation] 重症新生児黄疸を示したクリグラー・ナジャール症候群タイプIIの一家系2009

    • Author(s)
      青野幸子
    • Organizer
      日本未熟児新生児学会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2009-11-30
    • Data Source
      KAKENHI-PROJECT-21590606
  • [Presentation] 脳に特異的に発現するニューログリカンCのコンドロイチン硫酸鎖の役割2009

    • Author(s)
      青野幸子
    • Organizer
      日本神経科学学
    • Place of Presentation
      名古屋国際会議場(名古屋市)
    • Year and Date
      2009-09-18
    • Data Source
      KAKENHI-PROJECT-21590606
  • [Presentation] ニューログリカンC遺伝子改変マウスの行動解析2009

    • Author(s)
      青野幸子
    • Organizer
      日本神経化学会
    • Place of Presentation
      ホテル天坊(渋川市)
    • Year and Date
      2009-06-23
    • Data Source
      KAKENHI-PROJECT-21590606
  • [Presentation] Roles of the chondroitin sulfate chain on the core protein of neuroglycan C, a brain-specific transmembrane proteoglycan2009

    • Author(s)
      Aono, S.
    • Organizer
      日本神経科学学会
    • Place of Presentation
      名古屋国際会議場(名古屋)
    • Year and Date
      2009-09-18
    • Data Source
      KAKENHI-PROJECT-21590606
  • [Presentation] Behavioral analyses of mice which show abnormal expressions of neuroglycan C, a brain-specific chondroitin sulfate proteoglycan2009

    • Author(s)
      Aono, S.
    • Organizer
      日本神経化学会
    • Place of Presentation
      ホテル天坊(渋川)
    • Year and Date
      2009-06-23
    • Data Source
      KAKENHI-PROJECT-21590606
  • [Presentation] Three strains of mice which show abnormal expressions of neuroglycan C,a CNS-specific chondroitin sulfate proteoglycan2007

    • Author(s)
      Aono S.
    • Organizer
      21st Biennial Meeting of the International Society for Neurochemistry
    • Place of Presentation
      Cancun,Mexico
    • Year and Date
      2007-08-20
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17500246
  • [Presentation] The fifth splice variant of neuroglycan C,a CNS-specific transmembrane chondroitin sulfate proteoglycan2007

    • Author(s)
      Aono S.
    • Organizer
      第50回日本神経化学会大会
    • Place of Presentation
      横浜
    • Year and Date
      2007-09-12
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17500246
  • [Presentation] Three strains of mice which show abnormal expressions of neuroglycan C, a CNS-specific chondroitin sulfate proteoglycan2007

    • Author(s)
      Aono S.
    • Organizer
      21st Biennial Meeting of the International Society for Neurochemistry
    • Place of Presentation
      Cancun, Mexico(ハリケーンのため中止)
    • Year and Date
      2007-08-20
    • Data Source
      KAKENHI-PROJECT-17500246
  • [Presentation] The fifth splice variant of neuroglycan C, a CNS-specific transmembrane chondroitin sulfate proteoglycan2007

    • Author(s)
      Aono S.
    • Organizer
      第50回日本神経化学会大会
    • Place of Presentation
      横浜
    • Year and Date
      2007-09-12
    • Data Source
      KAKENHI-PROJECT-17500246
  • [Presentation] Three strains of mice which show abnormal expressions of neuroglycan C, a CNS-specific chondroitin sulfate proteoglycan2007

    • Author(s)
      Aono S.
    • Organizer
      21st Biennial Meeting of the International Society for Neurochemistry
    • Place of Presentation
      Cancun, Mexico(cancellation)
    • Year and Date
      2007-08-20
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500246
  • [Presentation] The fifth splice variant of neuroglycan C, a CNS- specific transmembrane chondroitin sulfate proteoglycan2007

    • Author(s)
      Aono S.
    • Organizer
      50th Annual Meeting of the Japanese Society for Neurochemistry
    • Place of Presentation
      Yokohama, Japan
    • Year and Date
      2007-09-12
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500246
  • [Presentation] 膜結合型コンドロイチン硫酸プロテオグリカンであるニューログリカンCの神経系における役割2006

    • Author(s)
      青野幸子
    • Organizer
      第6回神経組織プロテオグリカン研究会
    • Place of Presentation
      京都
    • Year and Date
      2006-07-22
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17500246
  • [Presentation] Chondroitin sulfate of neuroglycan C, a CNS specific transmembrane proteoglycan2006

    • Author(s)
      Aono S.
    • Organizer
      49th Annual Meeting of the Japanese Society for Neurochemistry
    • Place of Presentation
      Nagoya, Japan
    • Year and Date
      2006-09-14
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500246
  • [Presentation] Analysis of mice that show abnormal expression of neuroglycan C, a central nervous system specific transmembrane proteoglycan2006

    • Author(s)
      Aono S.
    • Organizer
      29thAnnual Meeting of the Japan Neuroscience Society
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      2006-07-20
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500246
  • [Presentation] Chondroitin sulfate of neuroglycan C,a CNS-specific transmembrane proteoglycan2006

    • Author(s)
      Aono S.
    • Organizer
      第49回日本神経化学会大会
    • Place of Presentation
      名古屋
    • Year and Date
      2006-09-14
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17500246
  • [Presentation] 神経系に特異的に発現するニューログリカンCの遺伝子改変マウスの解析2006

    • Author(s)
      青野幸子
    • Organizer
      第29回日本神経科学会大会
    • Place of Presentation
      京都
    • Year and Date
      2006-07-20
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17500246
  • [Presentation] A new splice valiant of neuroglycan C, a CNS specific transmembrane chondroitin sulfate proteoglycan2005

    • Author(s)
      Aono S.
    • Organizer
      48th Annual Meeting of the Japanese Society for Neurochemistry
    • Place of Presentation
      Fukuoka, Japan
    • Year and Date
      2005-09-29
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500246
  • [Presentation] A new splice valiant of neuroglycan C,a CNS-specific transmembrane chondroitin sulfate proteoglycan2005

    • Author(s)
      Aono S.
    • Organizer
      第48回日本神経化学会大会
    • Place of Presentation
      福岡
    • Year and Date
      2005-09-29
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17500246
  • 1.  TOKITA Yoshihito (50291175)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 2.  KEINO Hiroomi (30090426)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  NAGAE Hidetoshi
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  OZEKI Junnko
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  KOIWAI Osamu (50132923)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  OOHIRA Atsuhiko (20101074)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  BANNO Toshikazu
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  KAWASHIMA Sachiko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  長江 英利
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  鈴木 順子
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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