Arai Masami 新井正美

… Alternative Names

ARAI Masami 新井正美

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Researcher Number	20232027
Other IDs
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Affiliation (Current)	2025: 順天堂大学, 大学院医学研究科, 教授
Affiliation (based on the past Project Information) *help	2021 – 2023: 順天堂大学, 大学院医学研究科, 教授 2019 – 2020: 順天堂大学, 医学(系)研究科(研究院), 先任准教授 2016 – 2019: 公益財団法人がん研究会, 有明病院遺伝子診療部, 部長 2016: 公益財団法人がん研究会有明病院, 遺伝子診療部, 部長 2014: 公益財団法人がん研究会有明病院, 遺伝子診療部, 部長 … More 2004: 財団法人癌研究会, 癌研究所, 研究員 2000 – 2004: (財)癌研究会, 癌研究所, 研究員 2002: 財団法人癌研究会, 癌研究所, 研究員 2001: 財団法人癌研究会, 癌研究所, 研究員 Less
Review Section/Research Field	Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Digestive surgery / Experimental pathology Except Principal Investigator Biological Sciences / Basic Section 90140:Medical technology assessment-related / Tumor diagnostics / Risk sciences of radiation and chemicals / Digestive surgery
Keywords	Principal Investigator 化学予防 / リードスルー療法 / ナンセンス変異 / BRCA1 / HBOC / 遺伝性乳癌卵巣癌 / BRCA１ / 抗生剤 / がん予防 / APC遺伝子 … More / 遺伝性腫瘍 / 家族性大腸腺腫症 / マクロライド系抗生剤 / SNP / radiosensitivity / microsatellite instability / Radiation induced colorectal cancer / 射線誘発大腸癌 / 遺伝子多型 / 放射線感受性 / マイクロサテライト不安定性 / 放射線誘発大腸癌 / 胃癌 / HNPCC … More Except Principal Investigator 遺伝カウンセリング / 遺伝子診断 / HNPCC / 家族性腫瘍 / 臨床病理学的評価 / ゲノム情報 / 遺伝子発現解析 / ゲノム解析 / 遺伝子解析 / 疾患レジストリー / 遺伝性乳癌 / 稀少がん / 男性乳がん / レジストリー / 希少癌 / BRCA1/2 / VUS / 遺伝性乳癌卵巣がん症候群 / 男性乳癌 / 腫瘍DNAパネル / HypoMethylation / HyperMethylation / 超高感度定量 / 高感度定量 / 融解曲線解析 / リアルタイムPCR / メチル化DNA / Mozaicism / Liquid biopsy / Hypomethylation / Hypermethylation / DNA メチル化 / SEPT9 / BRCA1 / MLH1 / 超高感度定量解析 / 高解像度融解曲線解析 / がん / リキッドバイオプシー / 大腸がん / 定量的超高感度解析 / DNAメチル化 / 遺伝子改変ラット / 低線量 / 放射線発がん / 多発大腸癌 / MYH / 大腸癌 / ミスマッチ修復 / 大腸ポリポーシス / MAP / FAP / 家族性大腸腺腫症 / MUTYH / 病理標本活用 / 企業協同遺伝子検査試験 / 癌予防 / 家系データベース / 形質 / 遺伝子 / haploid conversion法 / hMSH2,hMLH1 / マイクロサテライト不安定性 / MSI / 遺伝性非ポリポージス大腸癌 Less

Establishment of read-through therapy in BRCA1 nonsense mutated cellsPrincipal Investigator
- Principal Investigator
  
  新井正美
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Juntendo University
Basic Study on Tumor Suppression Effects of Read-Through Therapy in Familial Colorectal AdenomatosisPrincipal Investigator
- Principal Investigator
  
  Arai Masami
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Juntendo University
Database development of male breast cancer in Japan
- Principal Investigator
  
  SAITO MITSUE
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90140:Medical technology assessment-related
- Research Institution
  Juntendo University
Devolopment for highly sensitive and quantitative methods with a facile, fast and low-cost protocol.
- Principal Investigator
  
  NOMURA Sachio
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor diagnostics
- Research Institution
  Japanese Foundation for Cancer Research
Development of novel breast cancer model for understanding individual susceptibility to low dose radiation
- Principal Investigator
  
  Imaoka Tatsuhiko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  National Institutes for Quantum and Radiological Science and Technology
Mutation analysis of MUTYH in Japanese colorectal adenomatous polyposis patients
- Principal Investigator
  
  TAKI Keiko
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Tokyo Institute of Technology
  Japanese Foundation for Cancer Research
癌研病院家族性腫瘍形質・遺伝子相関データベース構築
- Principal Investigator
  
  武藤徹一郎
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Japanese Foundation For Cancer Research
Genetic alterations in radiation-induced colorectal cancers and susceptibility to irradiationPrincipal Investigator
- Principal Investigator
  
  ARAI Masami
- Project Period (FY)
  2001 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Japanese Foundation for Cancer Research
癌研病院家族性腫瘍形質・遺伝子相関データベース構築
- Principal Investigator
  
  MUTO Tetsuichiro
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Japanese Foundation For Cancer Research
遺伝性非ポリポーシス大腸癌患者における胃癌・乳癌治療に関する基礎的研究Principal Investigator
- Principal Investigator
  
  新井正美
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Experimental pathology
- Research Institution
  Japanese Foundation For Cancer Research

All 2023 2021 2020 2017 2015 2014 2013 2012 2011 2005 2004 Other

All Journal Article Presentation Book Patent

[Book] 癌の遺伝医療2015
- Author(s)
  新井正美ほか（宮口健, 三木義男, 福嶋義光, 芦原有美, 西村誠一郎, 岩瀬晴子, ・・・,瀧景子, ・・)
- Total Pages
  256
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-23591977
[Book] 別冊・医学のあゆみ乳腺疾患-state of arts2004
- Author(s)
  新井正美
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-13470263
[Journal Article] Azithromycin induces read-through of the nonsense Apc allele and prevents intestinal tumorigenesis in C3B6F1 Apc/+ mice2023
- Author(s)
  Semba Ryoko、Morioka Takamitsu、Yanagihara Hiromi、Suzuki Kenshi、Tachibana Hirotaka、Hamoya Takahiro、Horimoto Yoshiya、Imaoka Tatsuhiko、Saito Mitsue、Kakinuma Shizuko、Arai Masami
- Journal Title
  
  Biomedicine & Pharmacotherapy
  
  Volume: 164 Pages: 114968-114968
- DOI
  10.1016/j.biopha.2023.114968
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07684, KAKENHI-PROJECT-21H04932
[Journal Article] A patient with hereditary breast and ovarian cancer syndrome who underwent contralateral risk-reducing mastectomy at age 70s2020
- Author(s)
  佐々木律子、堀本義哉、仙波遼子、村上郁、新井正美、齊藤光江
- Journal Title
  
  Journal of Hereditary Tumors
  
  Volume: 20 Issue: 3 Pages: 168-171
- DOI
  10.18976/jsht.20.3_168
- NAID
  130007964417
- ISSN
  2435-6808
- Year and Date
  2020-12-30
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07684
[Journal Article] A Case of a Child with an APC Pathogenic Mutation, Aberrant Expression of Splice Variants and Positive Family History of FAP2014
- Author(s)
  Keiko Taki, Yasuyoshi Sato, Yuri Sato, Yuumi Ashihara, Akiko Chino, Masahiro Igarashi, Koichiro Sato, Tomoyuki Kitagawa, Iruru Maetani, Chieko Nemoto, Kiyoto Nasuno, Takashi Sekine and Masami Arai
- Journal Title
  
  Japanese Journal of Clinical Oncology
  
  Volume: 44 Pages: 602-606
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23591977
[Journal Article] Clinical genetics for Hereditary cancers : from the viewpoint of physicians working at hospital specialized in cancer.2005
- Author(s)
  Arai M.
- Journal Title
  
  Jpn J Cancer Chemother 32(7)
  
  Pages: 948-953
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13470263
[Journal Article] Hereditary non-polyposis colorectal cancer.2005
- Author(s)
  Arai M.
- Journal Title
  
  Gastroenterological Surgery 28(5)
  
  Pages: 601-608
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13470263
[Journal Article] Familial breast cancer.2005
- Author(s)
  Arai M.
- Journal Title
  
  Genome Medicine 5(5)
  
  Pages: 69-77
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13470263
[Journal Article] 遺伝医療癌専門病院医師の立場から2005
- Author(s)
  新井正美
- Journal Title
  
  癌と化学療法 32
  
  Pages: 948-953
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13470263
[Journal Article] 家族性乳癌2005
- Author(s)
  新井正美
- Journal Title
  
  ゲノム医学 5
  
  Pages: 489-497
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13470263
[Journal Article] 遺伝性非ポリポーシス大腸癌2005
- Author(s)
  新井正美
- Journal Title
  
  消化器外科 28
  
  Pages: 601-608
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13470263
[Journal Article] 家族性大腸腫瘍の遺伝カウンセリング2004
- Author(s)
  新井正美
- Journal Title
  
  日本大腸肛門病学会誌 57・10
  
  Pages: 884-891
- NAID
  10014257342
- Data Source
  KAKENHI-PROJECT-13470263
[Journal Article] Familial breast and ovarian cancers.2004
- Author(s)
  Arai M
- Journal Title
  
  Int J Crin Oncol 9・4
  
  Pages: 270-282
- NAID
  10013569457
- Data Source
  KAKENHI-PROJECT-13470263
[Patent] 高感度かつ定量的な遺伝子検査方法、プライマーセット、及び検査キット2020
- Inventor(s)
  野村幸男、新井正美
- Industrial Property Rights Holder
  野村幸男、新井正美
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-539642
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-16K07153
[Patent] 特許権2017
- Inventor(s)
  野村幸男、新井正美
- Industrial Property Rights Holder
  公益財団法人がん研究会
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-168078
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-16K07153
[Presentation] リードスルー効果を有する既存薬によるがん予防法の可能性2023
- Author(s)
  森岡孝満、仙波遼子、鈴木健之、柳原啓見、今岡達彦、新井正美、齊藤光江、柿沼志津子
- Organizer
  第30回日本がん予防学会総会
- Data Source
  KAKENHI-PROJECT-20K07684
[Presentation] マクロライド系抗生剤のマウス消化管腫瘍に対するがん化学予防効果2021
- Author(s)
  仙波遼子、森岡孝満、柳原啓見、鈴木健之、柿沼志津子、堀本義哉、新井正美、齊藤光江
- Organizer
  第27回日本遺伝性腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07684
[Presentation] マクロライド系抗生剤のマウス消化管腫瘍に対するがん化学予防効果2021
- Author(s)
  仙波遼子、森岡孝満、柳原啓見、鈴木健之、柿沼志津子、堀本義哉、新井正美、齊藤光江
- Organizer
  第27回日本遺伝性腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07684
[Presentation] マクロライド系抗生剤のマウス消化管腫瘍抑制効果に関する検討2021
- Author(s)
  仙波遼子、森岡孝満、柳原啓見、鈴木健之、柿沼志津子、堀本義哉、新井正美、齊藤光江
- Organizer
  第28回がん予防学会総会
- Data Source
  KAKENHI-PROJECT-20K07684
[Presentation] A novel method for highly sensitive, facile and inexpensive quantitative assessment of aberrant DNA methylation in liquid biopsies2020
- Author(s)
  Sachio Nomura, Toshiyuki Kobayashi, Kiichi Sugimoto, Masami Arai, Kazuhiro Sakamoto, Thomas R. Pisanic II, Okio Hino.
- Organizer
  AACR Annual Meeting 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07153
[Presentation] Highly Sensitive DNA Methylation Analysis of MLH1 and BRCA12017
- Author(s)
  野村幸男、樋野興夫、新井正美
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K07153
[Presentation] APC 遺伝子に病的生殖細胞変異が同定できない多発性大腸ポリポーシス症例の遺伝子解析2013
- Author(s)
  瀧　景子、佐藤有理、芦原有美、上野雅資、五十嵐正広、新井正美
- Organizer
  第19回日本家族性腫瘍学会
- Place of Presentation
  大分県別府市
- Data Source
  KAKENHI-PROJECT-23591977
[Presentation] Current status of genetic counseling in Japan and approach in hereditary colorectal cancer syndrome in Cancer Institute Hospital2013
- Author(s)
  Yuumi Ashihara, Keiko Taki, Yuri Sato, Yasuko Yamanouchi, Masami Arai
- Organizer
  International Society for Gastrointestinal Hereditary Tumours 5th Biennial Meeting
- Place of Presentation
  Australia
- Data Source
  KAKENHI-PROJECT-23591977
[Presentation] APC 遺伝子変異が同定できない家族性大腸腺腫症症例に対するAPC 体細胞モザイクおよびMUTYH 遺伝子変異の解析2012
- Author(s)
  瀧景子,佐藤友理,菅野康吉,三木義男,新井正美
- Organizer
  第18回日本家族性腫瘍学会学術集会
- Place of Presentation
  大阪市
- Data Source
  KAKENHI-PROJECT-23591977
[Presentation] 家族性大腸腫瘍におけるメチル化異常の解析2012
- Author(s)
  瀧景子, 佐藤友理, 芦原有美, 新井正美
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡市
- Data Source
  KAKENHI-PROJECT-23591977
[Presentation] 多発性大腸ポリポーシス症例における遺伝子変異の解析2011
- Author(s)
  瀧　景子、佐藤友理、菅野康吉、新井正美、三木義男
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23591977
[Presentation] FFPE検体を用いたMLH1メチル化検出法の確立とリンチ症候群スクリーニング診断への応用
- Author(s)
  南　順子, 元井　紀子, 新井　正美, 野村　起美恵, Mahmut Yasen 2), Gulanbar Obulhasim 2), 瀧　景子, 佐藤　友里, 石川　雄一, 加藤　洋
- Organizer
  第60回日本病理学会秋期特別総会
- Place of Presentation
  沖縄県浦添市
- Year and Date
  2014-11-20 – 2014-11-21
- Data Source
  KAKENHI-PROJECT-23591977

1. MUTO Tetsuichiro (20110695)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. UTSUNOMIYA Jyoji (70013901)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. YANAGISAWA Akio (30137963)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. KATO You (20010473)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. Imaoka Tatsuhiko (40356134)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. TAKI Keiko (50332284)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
7. MIKI Yoshio (10281594)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. DAINO Kazuhiro (90543299)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. MORIOKA Takamitsu (70253961)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. NOMURA Sachio (70714773)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. SAITO MITSUE (30205679)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 真下知士 (80397554)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 石塚直樹 (50392395)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 樋野興夫 (90127910)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
15. 小林敏之 (40260070)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
16. 江口英孝 (00260232)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 堀本義哉 (40424246)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 柿沼志津子 (20392219)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
19. 佐藤友理

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
20. 芦原有美

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
21. 喜多瑞穂

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 上野雅資

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
23. 五十嵐正広

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
24. 福長洋介

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 長山聡

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 田島郁文

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Arai Masami 新井 正美

ARAI Masami 新井 正美

Research Projects

Research Products

Co-Researchers

Establishment of read-through therapy in BRCA1 nonsense mutated cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Basic Study on Tumor Suppression Effects of Read-Through Therapy in Familial Colorectal AdenomatosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Database development of male breast cancer in Japan

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Devolopment for highly sensitive and quantitative methods with a facile, fast and low-cost protocol.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of novel breast cancer model for understanding individual susceptibility to low dose radiation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mutation analysis of MUTYH in Japanese colorectal adenomatous polyposis patients

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

癌研病院家族性腫瘍形質・遺伝子相関データベース構築

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Genetic alterations in radiation-induced colorectal cancers and susceptibility to irradiationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

癌研病院家族性腫瘍形質・遺伝子相関データベース構築

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

遺伝性非ポリポーシス大腸癌患者における胃癌・乳癌治療に関する基礎的研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 癌の遺伝医療2015

Author(s)

Total Pages

Publisher

Data Source

[Book] 別冊・医学のあゆみ 乳腺疾患-state of arts2004

Author(s)

Publisher

Data Source

[Journal Article] Azithromycin induces read-through of the nonsense Apc allele and prevents intestinal tumorigenesis in C3B6F1 Apc/+ mice2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A patient with hereditary breast and ovarian cancer syndrome who underwent contralateral risk-reducing mastectomy at age 70s2020

Arai Masami 新井正美

ARAI Masami 新井正美

[Book] 別冊・医学のあゆみ乳腺疾患-state of arts2004

[Journal Article] 遺伝医療癌専門病院医師の立場から2005