KAMISAKO Toshinori 上硲俊法

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上硲俊法カミサコトシノリ

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Researcher Number	20233934
Other IDs
Affiliation (Current)	2025: 近畿大学, 大学病院, 教授
Affiliation (based on the past Project Information) *help	2019 – 2023: 近畿大学, 大学病院, 教授 2011 – 2018: 近畿大学, 医学部附属病院, 教授 2003 – 2004: 近畿大学, 医学部, 助教授
Review Section/Research Field	Principal Investigator Basic Section 59040:Nutrition science and health science-related / Eating habits / Applied pharmacology / Eating habits, studies on eating habits Except Principal Investigator Basic Section 59040:Nutrition science and health science-related / Food science
Keywords	Principal Investigator diosgenin / ethinylestradiol / MRP3 / MRP2 / ABC transporter / 魚油 / ezetimibe / 脂質代謝 / 糞便中性ステロール / pemafibrate … More / TICE / エゼチミブ / 経小腸コレステロール排泄 / エピジェネティックス / 脂肪酸代謝 / 後成的影響 / 高脂肪食 / 性差 / エピジェネティック / 胆汁酸代謝 / bile acid / bilirubin / cholestasis / 臓器相関 / ABCトランスポーター / 薬物輸送蛋白質 / 胆汁酸 / ビリルビン / 胆汁うっ滞 / ラード / 大豆油 / 脂肪酸組成 / 高コレステロール食 / 脂質組成 / 脂肪酸 / Nrf2 / 酸化ストレス … More Except Principal Investigator ABCG5/G8 / エゼチミブ / TICE / コレステロールトランスポーター / 小腸 / 総胆管結紮 / 胆汁鬱滞 / 解毒機構 / 毒性 / 植物ステロール / NPC1L1阻害剤 / ペマフィブラート / 脂質代謝異常 / 鉄過剰蓄積 / 非アルコール性脂肪肝炎 / 食品機能 / 脂肪肝炎 / 酸化ストレス / Nrf2 Less

Role of TICE in the efficacy and toxicity of plant sterols
- Principal Investigator
  
  TANAKA Yuji
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Kindai University
Role of the small intestine in dyslipidemia associated with cholestasis
- Principal Investigator
  
  TANAKA Yuji
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Kindai University
Effect of dietary lipid composition on trans-intestinal cholesterol excretionPrincipal Investigator
- Principal Investigator
  
  KAMISAKO Toshinori
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Kindai University
Effect of maternal nutrition during pregnancy on lipid metabolism including lipid absorption of offspringPrincipal Investigator
- Principal Investigator
  
  KAMISAKO Toshinori
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Eating habits
- Research Institution
  Kindai University
Role of dietary lipid composition on the crosstalk mechanism between lipid metabolism and oxidative stress regulation.Principal Investigator
- Principal Investigator
  
  KAMISAKO Toshinori
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Eating habits, studies on eating habits
- Research Institution
  Kinki University
Elucidation of the mechanism of onset of steatohepatitis and prevention of pathogenesis with the food ingredients by targeting Nrf2
- Principal Investigator
  
  TANAKA Yuji
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Food science
- Research Institution
  Kinki University
Role of renal and inteslinal ABC transporters during cholestatic liver diseasePrincipal Investigator
- Principal Investigator
  
  KAMISAKO Toshinori
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  KINKI UNIVERSITY

All 2024 2023 2020 2019 2018 2016 2014 2013 2012 2004 Other

All Journal Article Presentation

[Journal Article] Ezetimibe Markedly Reduces Hepatic Triglycerides and Cholesterol in Rats Fed on Fish Oil by Increasing the Expression of Cholesterol Efflux Transporters2020
- Author(s)
  Tanaka Yuji、Ikeda Takanori、Ogawa Hiroshi、Kamisako Toshinori
- Journal Title
  
  Journal of Pharmacology and Experimental Therapeutics
  
  Volume: 374 Issue: 1 Pages: 175-183
- DOI
  10.1124/jpet.120.265660
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K11006, KAKENHI-PROJECT-18K11115
[Journal Article] Gender-divergent expression of lipid and bile acid metabolism related genes in adult mice offspring of dams fed a high-fat diet2018
- Author(s)
  Yuji Tanaka, Takanori Ikeda, Kazuo Yamamoto, Shiori Masuda, Hiroshi Ogawa, Toshinori Kamisako
- Journal Title
  
  J Biosciences
  
  Volume: ー
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K00860
[Journal Article] Role of Nrf2 in the alteration of cholesterol and bile acid metabolism-related gene expression by dietary cholesterol in high fat-fed mice2014
- Author(s)
  Toshinori Kamisako, Yuji Tanaka, Yoshizumi Kishino, Takanori Ikeda, Kazuo Yamamoto, Shiori Masuda, Hiroshi Ogawa
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 54 Issue: 2 Pages: 90-94
- DOI
  10.3164/jcbn.13-92
- NAID
  130004879357
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24501010
[Journal Article] Ezetimibe increases hepatic iron levels in mice fed a high-fat diet2013
- Author(s)
  Yoshizumi Kishino ,Yuji Tanaka, Takanori Ikeda, Kazuo Yamamoto, Hiroshi Ogawa, Yoshinori Iwatani, Toshinori Kamisako.
- Journal Title
  
  J Pharmacol Exp Ther
  
  Volume: 345 Issue: 3 Pages: 483-491
- DOI
  10.1124/jpet.113.203448
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24501010
[Journal Article] Dysregulated expression of fatty acid oxidation enzymes and iron-regulatory genes in livers of Nrf2-null mice2012
- Author(s)
  Tanaka Y, Ikeda T, Yamamoto K, Ogawa H, Kamisako T.
- Journal Title
  
  Journal of Gastroenterology and Hepatology
  
  Volume: 27 Issue: 11 Pages: 1711-1717
- DOI
  10.1111/j.1440-1746.2012.07180.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23580188
[Journal Article] Effects of pravastatin and bezafibrate on biliary lipid excretion and hepatic expressions of Abcg5 and Abcg8 in the rats.2004
- Author(s)
  Toshinori Kamisako, Hiroshi Ogawa
- Journal Title
  
  J Gastroenterol Hepatol 19
  
  Pages: 879-883
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590473
[Journal Article] Effects of pravastatin and bezafibrate on biliary lipid excretion and hepatic expressions of Abcg5 and Abcg8 in the rats.2004
- Author(s)
  Toshinori Kamisako, Hiroshi Ogawa
- Journal Title
  
  Journal of Gastroenterology and Hepatology 19
  
  Pages: 879-883
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590473
[Journal Article] Alteration of the expression of ATP binding cassette transporters associated with bile acid and cholesterol transport in the rat liver and intestine during cholestasis.
- Author(s)
  Toshinori Kamisako, Hiroshi Ogawa
- Journal Title
  
  Journal of Gastroenterology and Hepatology (in press)
- Data Source
  KAKENHI-PROJECT-15590473
[Journal Article] Alteration of the expression of ATP binding cassette transporters associated with bile acid and cholesterol transport in the rat liver and intestine during cholestasis.
- Author(s)
  Toshinori Kamisako, Hiroshi Ogawa
- Journal Title
  
  J Gastroenterol Hepatol (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590473
[Journal Article] Alteration of the expression of ATP binding cassette transporters associated with bile acid and cholesterol transport in the rat liver and intestine during cholestasis.
- Author(s)
  Toshinori Kamisako, Hiroshi Ogawa
- Journal Title
  
  Journal of Gastroenterology and Hepatology (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590473
[Presentation] Differential regulation of intestinal sterol efflux transporters and non-biliary cholesterol excretion by dietary oil in bile duct-ligated rats.2024
- Author(s)
  Tanaka Yuji, Kamisako Toshinori
- Organizer
  The Society of Toxicology (SOT) 63rd Annual Meeting and ToxExpo
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K11740
[Presentation] 油脂成分の体内蓄積が小腸コレステロール排泄機構に及ぼす影響-大豆油と魚油の比較2023
- Author(s)
  田中裕滋, 上硲俊法
- Organizer
  第62回日本栄養・食糧学会近畿支部大会
- Data Source
  KAKENHI-PROJECT-21K11740
[Presentation] Adaptive regulation of bile acid and cholesterol transporters in mouse kidney and intestine during alpha-naphthylisothiocyanate (ANIT)-induced cholestasis2020
- Author(s)
  Tanaka Yuji、Ikeda Takanori、Ogawa Hiroshi、Kamisako Toshinori
- Organizer
  The59th Annual Meeting of the Society of toxicology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K11006
[Presentation] 高脂肪食摂取マウスにおけるワサビ由来6-メチルスルフィニルヘキシルイソチオシアネートのNrf2を介した脂肪改善作用2019
- Author(s)
  田中裕滋, 池田高紀, 小川　博, 上硲俊法
- Organizer
  第73回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-18K11006
[Presentation] 高脂肪食を摂取した母親から生まれた仔マウスの成長後の胆汁酸関連遺伝子発現の性差2019
- Author(s)
  田中裕滋, 上硲俊法
- Organizer
  第55回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-18K11006
[Presentation] Increased non-biliary cholesterol excretion during alpha-naphthylisothiocyanate (ANIT)-induced cholestasis in mice2019
- Author(s)
  Yuji Tanaka, Takanori Ikeda, Hiroshi Ogawa, Toshinori Kamisako
- Organizer
  The 58th Annual Meeting of the Society of Toxicology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K11006
[Presentation] Ezetimibe markedly reduces hepatic triglycerides and cholesterol in fishoil-fed rats2019
- Author(s)
  Yuji Tanaka, Takanori Ikeda, Hiroshi Ogawa, Toshinori Kamisako
- Organizer
  The 70th Annual Meeting of the American Association for theStudy of Liver Diseases
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K11006
[Presentation] EZETIMIBE MARKEDLY REDUCES HEPATIC TRIGLYCERIDES AND CHOLESTEROL IN FISH OIL-FED RATS2019
- Author(s)
  Yuji Tanaka, Takanori Ikeda, Kazuo Yamamoto, Hiroshi Ogawa, Toshinori Kamisako.
- Organizer
  Liver Meeting 2019, The American Association for Study of the Liver Disease (Boston)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K11115
[Presentation] 魚油含有食摂取がマウスの脂質・胆汁酸代謝に及ぼす影響2018
- Author(s)
  田中裕滋, 池田高紀, 山本和夫, 小川　博, 上硲俊法
- Organizer
  第72回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-18K11006
[Presentation] Gender-divergent expression of lipid and bile acid metabolism related genes in adult offspring of dams fed a long-term high fat diet before and during pregnancy and lactation.2016
- Author(s)
  Yuji Tanaka, Takanori Ikeda, Kazuo Yamamoto, Hiroshi Ogawa, Toshinori Kamisako.
- Organizer
  Liver Meeting 2016, The American Association for Study of the Liver Disease
- Place of Presentation
  Boston (USA)
- Year and Date
  2016-11-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K00860
[Presentation] ワサビ由来6-メチルスルフィニルヘキシルイソチオシアネートはマウスの高脂肪食誘発性脂肪肝をNrf2依存性に改善する2014
- Author(s)
  田中裕滋、池田高紀、山本和夫、小川博、上硲俊法
- Organizer
  第50回日本肝臓学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23580188
[Presentation] Wasabi derivative 6-methylsulfinylhexyl isothiocyanate, a potent Nrf2 activator, prevents the fatty liver produced by a high-fat diet but did not attenuate hepatic iron overload in mice2013
- Author(s)
  Yuji Tanaka, Toshinori Kamisako
- Organizer
  64th Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  Washington, D.C., USA
- Data Source
  KAKENHI-PROJECT-23580188
[Presentation] 高脂肪食摂取マウスにおけるエゼチミブ投薬による肝内鉄値増加2013
- Author(s)
  田中裕滋　岸野好純　池田高紀　山本和夫　小川博　上硲俊法
- Organizer
  第49回日本肝臓学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24501010
[Presentation] 高脂肪食摂取Nrf2欠損マウスにおけるオルチプラズによる肝障害の改善効果2013
- Author(s)
  田中裕滋　池田高紀　山本和夫　小川博　上硲俊法
- Organizer
  第49回日本肝臓学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24501010
[Presentation] ワサビ由来6-メチルスルフィニルヘキシルイソチオシアネートはマウスの高脂肪食誘発性脂肪肝をNrf2依存性に改善する
- Author(s)
  田中裕滋　池田高紀　山本和夫　小川博　上硲俊法
- Organizer
  第50回日本肝臓学会総会
- Place of Presentation
  東京（ホテルニューオータニ）
- Year and Date
  2014-05-29 – 2014-05-30
- Data Source
  KAKENHI-PROJECT-24501010

1. TANAKA Yuji (00465650)

# of Collaborated Projects: 6 results

# of Collaborated Products: 19 results
2. OGAWA Hiroshi (00133546)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results

KAMISAKO Toshinori 上硲 俊法

上硲 俊法 カミサコ トシノリ

Research Projects

Research Products

Co-Researchers

Role of TICE in the efficacy and toxicity of plant sterols

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of the small intestine in dyslipidemia associated with cholestasis

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Effect of dietary lipid composition on trans-intestinal cholesterol excretionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Effect of maternal nutrition during pregnancy on lipid metabolism including lipid absorption of offspringPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of dietary lipid composition on the crosstalk mechanism between lipid metabolism and oxidative stress regulation.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of the mechanism of onset of steatohepatitis and prevention of pathogenesis with the food ingredients by targeting Nrf2

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of renal and inteslinal ABC transporters during cholestatic liver diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Ezetimibe Markedly Reduces Hepatic Triglycerides and Cholesterol in Rats Fed on Fish Oil by Increasing the Expression of Cholesterol Efflux Transporters2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Gender-divergent expression of lipid and bile acid metabolism related genes in adult mice offspring of dams fed a high-fat diet2018

Author(s)

Journal Title

Data Source

[Journal Article] Role of Nrf2 in the alteration of cholesterol and bile acid metabolism-related gene expression by dietary cholesterol in high fat-fed mice2014

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Ezetimibe increases hepatic iron levels in mice fed a high-fat diet2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dysregulated expression of fatty acid oxidation enzymes and iron-regulatory genes in livers of Nrf2-null mice2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects of pravastatin and bezafibrate on biliary lipid excretion and hepatic expressions of Abcg5 and Abcg8 in the rats.2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Effects of pravastatin and bezafibrate on biliary lipid excretion and hepatic expressions of Abcg5 and Abcg8 in the rats.2004

KAMISAKO Toshinori 上硲俊法

上硲俊法カミサコトシノリ