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NASU Yasutomo  那須 保友

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… Alternative Names

那須 保友  ナス ヤスモト

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Researcher Number 20237572
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2021 – 2023: 岡山大学, 医歯薬学域, 教授
2016 – 2020: 岡山大学, 医歯薬学総合研究科, 教授
2015: 岡山大学, 医歯(薬)学総合研究科, 教授
2015: 岡山大学, 大学院医歯薬学総合研究科, 教授
2014: 岡山大学, 岡山大学病院, 教授 … More
2011 – 2014: 岡山大学, 大学病院, 教授
2009 – 2011: 岡山大学, 岡山大学病院, 教授
2010: 岡山大学, 病院, 教授
2009: Okayama University, 大学病院, 教授
2008: 岡山大学, 医歯薬学総合研究科, 准教授
2007 – 2008: Okayama University, 大学院・医歯薬学総合研究科, 准教授
2005 – 2006: Okayama University, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Associate Professor, 大学院・医歯薬学総合研究科, 助教授
2005 – 2006: 岡山大学, 大学院医歯薬学総合研究科, 助教授
2004: 岡山大学, 大学院・医歯学総合研究科, 助教授
2003: 岡山大学, 医学部・歯学部附属病院, 講師
2002: Okayama University, Graduate School of Medicine and Dentistry, Assistant Professor, 医学部附属病院, 講師
1999 – 2001: 岡山大学, 医学部・附属病院, 講師
1995: 岡山大学, 医学部・附属病院, 講師 Less
Review Section/Research Field
Principal Investigator
Urology / Urology / Basic Section 56030:Urology-related
Except Principal Investigator
Urology / Basic Section 56030:Urology-related / Urology / Gastroenterology / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Obstetrics and gynecology
Keywords
Principal Investigator
前立腺癌 / REIC / 遺伝子治療 / prostate cancer / サイトカイン / JNK / 腫瘍学 / 膀胱癌 / 免疫原性 / 癌抗原 … More / Bax / DKK / MRP / MDR / gene therapy / 癌免疫 / 抗癌免疫 / 腎細胞癌 / REIC/Dkk-3 / 尿路腫瘍 / がん免疫 / 融合タンパク質 / CD147 / Adenovirus / Prostate cancer / Renal cancer / Apoptosis / 精巣腫瘍 / アデノウイルス / 前立腺がん / 腎がん / アポトーシス / baladder cancer / androgen / Caveolin / アンドロゲン / カベオリン / solid tumor / 固形癌 / ultrasonography / 同所移植 / 超音波断層法 / 免疫学 / がん / タンパク質 / STAT / 癌 / ノックアウトマウス / 蛋白治療. / REIK/DKK-3 / 樹状細胞 / HSP70 / Dkk-3 / Dkk3 / P-glycoprotein / DKK3 / ストレス応答分子 / 薬剤耐性 / 遺伝子治療学 / 遺伝子導入 / 生分解性ポリマー / 生分解 / テーラーメイド / ポリマー / DNA ploidy / フローサイトメトリー / レクチン / 糖鎖抗原 … More
Except Principal Investigator
遺伝子治療 / 前立腺癌 / prostate cancer / 腫瘍 / REIC/Dkk-3 / 腫瘍学 / 局所治療 / REIC/DKK-3 / REIC / Interleukin-12 / 樹状細胞 / NY-ESO-1 / adenovirus vector / gene therapy / アデノウイルスベクター / 5-fluorouracil / 膀胱癌 / 細胞検出 / 膵癌 / REIC遺伝子 / インターロイキン12 / 尿路性器癌 / ホルモン治療 / 治療抵抗性前立腺癌 / microtubule / in vivo投与モデル / 幹細胞 / 間葉系幹細胞 / Dynamin / 癌 / in vivo投与法 / エンドサイトーシス / 細胞骨格 / in vivo投与 / 細胞内輸送 / 癌創薬 / 内視鏡 / 薬剤投与法 / アデノウイルス / 癌ウイルス治療 / 標的治療 / iPS細胞 / ips細胞 / 癌幹細胞 / 前立腺がん / チェックポイント阻害薬 / 癌免疫 / 免疫活性 / 抗癌免疫制御 / 制限増殖型アデノウイルスベクター / 抗癌免疫活性化 / 癌ワクチン / 限増殖型アデノウイルスベクター / 肝臓癌 / 腫瘍免疫 / DKK3 / Prostate Cancer / cancer immunology / Gene therapy / Dendritic cell / 抗腫瘍免疫 / dendritic cell / HV-tk / tumor associated antigen / 自殺遺伝子 / HSV-tk / 腫瘍抗原 / surgery / physical slate / cervical dysplasia / cervical cancer / Human Papilloma Virus / 子宮頚癌 / ヒトパピロース・ウイルス / 手術 / 存在様式 / 子宮頚部異型上皮 / 子宮頸癌 / ヒトパピローマウイルス / Uracil phosphoribosy 1 transferas / Bladder cancer / pro-drug gene therapy / Uracil phosphoribosy1 transferase / Uracil phosphoribosyl transferase / 薬剤感受性遺伝子治療 / caveolin / アンドロゲン / Careolin / カベオリン / エンハンサー / CMV / SV40 / hTERT / 遺伝子発現 / 自己癌ワクチン化 / 癌遺伝子治療 / 消化器癌 / 癌抑制遺伝子 / 膵臓癌 / 癌化 / 前立腺 / Bip/GRP78 / 前立腺分化 / GRP78 / BiP / Akt / Ras-GTP / Ras / 不死化関連遺伝子 / IL-12 / 非ウイルスベクター / 高密度焦点超音波(HIFU) / 遺伝子導入 / 高密度焦点超音波 / 制限増殖型アデノウイルス / テロメラーゼ・プロモーター Less
  • Research Projects

    (32 results)
  • Research Products

    (137 results)
  • Co-Researchers

    (45 People)
  •  Elucidation of the mechanism of oncogenic-steroid signaling axis in hormone therapy-resistant prostate cancer

    • Principal Investigator
      Kobayashi Yasuyuki
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Okayama University
  •  Establishment and application development of innovative ablation technology for bladder cancer

    • Principal Investigator
      Edamura Kouhei
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Okayama University
  •  Elucidation of molecular transport control systems based on cytoskeleton dynamics and new developments in innovative cancer drug discovery.

    • Principal Investigator
      Watanabe Masami
    • Project Period (FY)
      2019 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
    • Research Institution
      Okayama University
  •  Basic research on next-generation gene therapy using restricted-replication adenovirus

    • Principal Investigator
      Kobayashi Yasuyuki
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Okayama University
  •  Adaptive immunity optimization targeting the novel cancer antigen CD147 and its application development in urinary genital tumorsPrincipal Investigator

    • Principal Investigator
      Nasu Yasutomo
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Okayama University
  •  The mechanism of release from immune exhaustion in tumor by a novel checkpoint inhibitor

    • Principal Investigator
      Sadahira Takuya
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Okayama University
  •  Establishment of a new gene therapy strategy for prostate cancer stem cells

    • Principal Investigator
      HUANG PENG
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Okayama University
  •  制限増殖型アデノウィルスを用いた次世代遺伝子治療の基盤研究

    • Principal Investigator
      EBARA Shin
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Okayama University
  •  Optimisation of a cancer detection and isolation technique using hTERT promoter, and establishment of its applicational foundation

    • Principal Investigator
      Ueki Hideo
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Okayama University
  •  The analysis of the function and the clinical application of REIC/ Dkk-3 gene in digestive organ cancer

    • Principal Investigator
      Kato Hironari
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Okayama University
  •  Elucidation of the establishment of prostatic antigen presenting ability in dendritic cells, and development of novel medicinesPrincipal Investigator

    • Principal Investigator
      Nasu Yasutomo
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Urology
    • Research Institution
      Okayama University
  •  Development of novel cancer vaccine therapy using oncolytic Ad-REIC

    • Principal Investigator
      huang peng
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Urology
    • Research Institution
      Okayama University
  •  Development of a novel technique for the detection and isolation of disseminated cancer cells, and establishment of its application foundation

    • Principal Investigator
      UEKI HIDEO
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Okayama University
  •  尿路癌に対する次世代癌免疫療法の創成

    • Principal Investigator
      賀来 春紀
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Okayama University
  •  A novel therapeutic strategy for prostate cancer treatment with anti-cancer immunological proteins.Principal Investigator

    • Principal Investigator
      NASU Yasutomo
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Urology
    • Research Institution
      Okayama University
  •  The analysis of the function and the clinical application of REIC/Dkk-3 gene in digestive organ cancer

    • Principal Investigator
      KATO Hironari
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Okayama University
  •  Basic and developmental research of a novel anti-tumor protein with dendritic cell-inducible activity.Principal Investigator

    • Principal Investigator
      NASU Yasutomo
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Urology
    • Research Institution
      Okayama University
  •  The molecular function of immortalization-related genes in the regulation of Oncogenic Ras and prostatic carcinogenesis.

    • Principal Investigator
      KUMON Hiromi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Urology
    • Research Institution
      Okayama University
  •  Novel approach with sonoporation in IL12 gene therapy for prostate cancer.

    • Principal Investigator
      SAIKA Takashi
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Okayama University
  •  Fundamental research for new molecular mechanism of anticancer resistance in urogenital cancerPrincipal Investigator

    • Principal Investigator
      NASU Yasutomo
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Urology
    • Research Institution
      Okayama University
  •  The development study of the new gene therapy that assumed telomerase activity for urinary cancers.

    • Principal Investigator
      KAKU Haruki
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Okayama University
  •  生分解性ポリマーを用いたテーラーメイド型遺伝子治療用ベクターの開発研究Principal Investigator

    • Principal Investigator
      那須 保友
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Urology
    • Research Institution
      Okayama University
  •  Development of cell and gene therapy for prostate cancer with dendritic cells engineered to produce interleukin-12

    • Principal Investigator
      SAIKA Takashi
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Okayama University
  •  DEVELOPMENT OF TAILORED-MADE TYPE PROSTATE CANCER GENE THERAPY AIMING AT SYSTEMIC IMMUNE-ACTIVATION

    • Principal Investigator
      KUMON Hiromi
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Urology
    • Research Institution
      Okayama University
  •  Research on Functional Analysis and Clinical application of New Tumor-associated Gene (REIC) in Urogenital CancerPrincipal Investigator

    • Principal Investigator
      NASU Yasutomo
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Urology
    • Research Institution
      Okayama University
  •  DEVELOPMENT AND CLINICAL APPLICATION OF VECTOR INJECTION DEVICE FOR GENE THERAPY OF SOLID TUMORPrincipal Investigator

    • Principal Investigator
      NASU Yasutomo
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Urology
    • Research Institution
      Okayama University
  •  Basic and clinical Research for Caveolin as a therapeutic target for urogenital cancerPrincipal Investigator

    • Principal Investigator
      NASU Yasutomo
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Okayama University
  •  ENHANCEMENT OF BYSTANDER EFFECTS WITH THE COMBINATION OF IMMUNO-GENE THERAPY AND PRO-DRUG GENE THERAPY

    • Principal Investigator
      KUMON Hiromi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Okayama University
  •  Eradication of HPV post surgical treatments, its correlation with specific types, type of surgeries, and the physical status

    • Principal Investigator
      YOSHINOUCHI Mitsuo
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      OKAYAMA UNIVERSITY
  •  Caveolin expression and androgen independent growth of prostate cancer

    • Principal Investigator
      TSUSHIMA Tomoyasu
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      OKAYAMA UNIVERSITY
  •  Establishment of evaluating system for the efficacy of the prostate cancer gene therapy using orthotopic mouse tumor modelPrincipal Investigator

    • Principal Investigator
      NASU Yasutomo
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      OKAYAMA UNIVERSITY
  •  表在性膀胱癌の細胞表面糖鎖抗原の定量化についてPrincipal Investigator

    • Principal Investigator
      那須 保友
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Okayama University

All 2023 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation Book Patent

  • [Book] REIC/Dkk-3 gene therapy2011

    • Author(s)
      Watanabe M, Kaku H, Huang P, Kumon H, Nasu Y
    • Publisher
      Nihon Rinsho
    • Data Source
      KAKENHI-PROJECT-21390441
  • [Book] Suicide gene and immuno gene therapy for prostate cancer2011

    • Author(s)
      Nasu Y, Sasaki K, Kumon H, Kaku H, Watanabe M
    • Publisher
      Nihon Rinsho
    • Data Source
      KAKENHI-PROJECT-21390441
  • [Book] 遺伝子治療の最先端泌尿器疾患治療の新しいストラテジー(村井勝, 奥山明彦, 内藤誠二編)2007

    • Author(s)
      賀来春紀, 那須保友, 公文裕巳
    • Total Pages
      793
    • Publisher
      メジカルビューシャ, 東京
    • Data Source
      KAKENHI-PROJECT-18591754
  • [Book] 泌尿器疾患治療の新しいストラテジー2007

    • Author(s)
      賀来春紀, 那須保友, 公文裕巳(村井 勝, 奥山明彦, 内藤誠二編)
    • Total Pages
      404
    • Publisher
      メジカルビュー社
    • Data Source
      KAKENHI-PROJECT-17659505
  • [Book] Endourology New Hrizon in Endourology (Editor H.Kumon)2005

    • Author(s)
      Y.Nasu, F.Abarzua, H.Kunon
    • Total Pages
      177
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-15390491
  • [Book] Endourology New Hrizon in Endourologv (Editor H. Kumon)2005

    • Author(s)
      Y.Nasu, F.Abarzua, H.Kumon
    • Total Pages
      177
    • Publisher
      Sprlnger
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390491
  • [Journal Article] Pacsin 2-dependent N-cadherin internalization regulates the migration behaviour of malignant cancer cells2023

    • Author(s)
      Haymar Wint, Jianzhen Li, Tadashi Abe, Hiroshi Yamada, Takumi Higaki, Yasutomo Nasu, Masami Watanabe, Kohji Takei, Tetsuya Takeda
    • Journal Title

      Journal of Cell Science

      Volume: 136(10) Issue: 10

    • DOI

      10.1242/jcs.260827

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19KK0180, KAKENHI-PROJECT-22K06580, KAKENHI-PROJECT-22H04926, KAKENHI-PROJECT-19H01064
  • [Journal Article] The Novel Combination of Nitroxoline and PD-1 Blockade, Exerts a Potent Antitumor Effect in a Mouse Model of Prostate Cancer2019

    • Author(s)
      Naijin Xu, Linglong Huang, Xiezhao Li, Masami Watanabe, Chaoming Li, Abai Xu, Chunxiao Liu, Qiang Li, Motoo Araki, Koichiro Wada, Yasutomo Nasu, Peng Huang
    • Journal Title

      International Journal of Biological Sciences

      Volume: 15 Issue: 5 Pages: 919-928

    • DOI

      10.7150/ijbs.32259

    • Data Source
      KAKENHI-PROJECT-17K11138
  • [Journal Article] Induction of cells with prostate cancer stem-like properties from mouse induced pluripotent stem cells via conditioned medium2018

    • Author(s)
      Xu N, Li X, Watanabe M, Ueki H, Hu H, Li N, Araki M, Wada K, Xu A, Liu C, Nasu Y, Huang P
    • Journal Title

      Am J Cancer Res

      Volume: 8 Pages: 1624-1632

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11138
  • [Journal Article] Exogenous DKK-3/REIC inhibits Wnt/β-catenin signaling and cell proliferation in human kidney cancer KPK12017

    • Author(s)
      Xu Jiaqi、Sadahira Takuya、Kinoshita Rie、Li ShunAi、Huang Peng、Wada Koichiro、Araki Motoo、Ochiai Kazuhiko、Noguchi Hirofumi、Sakaguchi Masakiyo、Nasu Yasutomo、Watanabe Masami
    • Journal Title

      Oncology Letters

      Volume: 14 Pages: 5638-5642

    • DOI

      10.3892/ol.2017.6833

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K11138, KAKENHI-PROJECT-17H00769, KAKENHI-PROJECT-16H05404, KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-16K18440
  • [Journal Article] Synergistic effects of the immune checkpoint inhibitor CTLA-4 combined with the growth inhibitor lycorine in a mouse model of renal cell carcinoma2017

    • Author(s)
      Li Xiezhao、Xu Peng、Wang Chongshan、Xu Naijin、Xu Abai、Xu Yawen、Sadahira Takuya、Araki Motoo、Wada Koichiro、Matsuura Eiji、Watanabe Masami、Zheng Junxia、Sun Pinghua、Huang Peng、Nasu Yasutomo、Liu Chunxiao
    • Journal Title

      Oncotarget

      Volume: 8 Issue: 13 Pages: 21177-21186

    • DOI

      10.18632/oncotarget.15505

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11138
  • [Journal Article] Promising therapeutic efficacy of a novel REIC/Dkk-3 expressing adenoviral vector for hepatocellular carcinoma.2017

    • Author(s)
      Sawahara H, Shiraha H, Uchida D, Kato H, Kato R, Oyama A, Nagahara T, Iwamuro M, Horiguchi S, Tsutsumi K, Mandai M, Mimura T, Wada N, Takeuchi Y, Kuwaki K, Onishi H, Nakamura S, Watanabe M, Sakaguchi M, et al.
    • Journal Title

      J Gastroenterol Hepatol.

      Volume: - Issue: 10 Pages: 1769-1777

    • DOI

      10.1111/jgh.13757

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26290039, KAKENHI-PROJECT-26293352, KAKENHI-PROJECT-15K14382, KAKENHI-PROJECT-25220206, KAKENHI-PROJECT-15H04974, KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-15K08999, KAKENHI-PROJECT-15K09001
  • [Journal Article] Robust cancer-specific gene expression by a novel cassette with hTERT and CMV promoter elements.2017

    • Author(s)
      Sakaguchi M, Sadahira T, Ueki H, Kinoshita R, Murata H, Yamamoto KI, Futami J, Nasu Y, Ochiai K, Kumon H, Huh NH, Watanabe M.
    • Journal Title

      Oncology Reports

      Volume: 38 Issue: 2 Pages: 1108-1114

    • DOI

      10.3892/or.2017.5710

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K11004, KAKENHI-PROJECT-16K19037, KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-16K18440
  • [Journal Article] Tumor suppressor REIC/DKK-3 and co-chaperone SGTA: Their interaction and roles in the androgen sensitivity2016

    • Author(s)
      Ochiai K, Morimatsu M, Kato Y, Ishiguro-Oonuma T, Udagawa C, Rungsuriyawiboon O, Azakami D, Michishita M, Ariyoshi Y, Ueki H, Nasu Y, Kumon H, Watanabe M, Omi T.
    • Journal Title

      Oncotarget

      Volume: 7 Issue: 3 Pages: 3283-3296

    • DOI

      10.18632/oncotarget.6488

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25462478, KAKENHI-PROJECT-26292161, KAKENHI-PROJECT-26293352, KAKENHI-PROJECT-26450400, KAKENHI-PROJECT-15K07754
  • [Journal Article] MCAM, as a novel receptor for S100A8/A9, mediates progression of malignant melanoma through prominent activation of NF-κB and ROS formation upon ligand binding.2016

    • Author(s)
      Ruma IM, Putranto EW, Kondo E, Murata H, Watanabe M, Huang P, Kinoshita R, Futami J, Inoue Y, Yamauchi A, Sumardika IW, Youyi C, Yamamoto K, Nasu Y, Nishibori M, Hibino T, Sakaguchi M.
    • Journal Title

      Clin Exp Metastasis

      Volume: 33 Issue: 6 Pages: 609-627

    • DOI

      10.1007/s10585-016-9801-2

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26290039, KAKENHI-PROJECT-15K14382, KAKENHI-PROJECT-15K20093, KAKENHI-PROJECT-15K10201, KAKENHI-PROJECT-16K08728, KAKENHI-PROJECT-16K15245
  • [Journal Article] A vaccine strategy with multiple prostatic acid phosphatase-fused cytokines for prostate cancer treatment2015

    • Author(s)
      Fujio K, Watanabe M, Ueki H, Li SA, Kinoshita R, Ochiai K, Futami J, Watanabe T, Nasu Y, Kumon H.
    • Journal Title

      Oncology Reports

      Volume: 33 Issue: 4 Pages: 1585-1592

    • DOI

      10.3892/or.2015.3770

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25462478, KAKENHI-PROJECT-15H04974
  • [Journal Article] Synergistic anti-pancreatic cancer immunological effects by treatment with REIC/DKK3 protein and peripheral blood mononuclear cells.2015

    • Author(s)
      Uchida D, Shiraha H, Kato H, Sawahara H, Nagahara T, Iwamuro M, Kataoka J, Horiguchi S, Watanabe M, Takaki A, Nouso K, Nasu Y, Kumon H, Yamamoto K
    • Journal Title

      J Gastroenterol Hepatol

      Volume: - Issue: 6 Pages: 1154-1159

    • DOI

      10.1111/jgh.13259

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26293352, KAKENHI-PROJECT-15H04297, KAKENHI-PROJECT-15H04974, KAKENHI-PROJECT-25220206
  • [Journal Article] Integrin antagonist augments the therapeutic effect of adenovirus-mediated REIC/Dkk-3 gene therapy for malignant glioma.2014

    • Author(s)
      Shimazu Y, Kurozumi K, Ichikawa T, Fujii K, Onishi M, Ishida J, Oka T, Watanabe M, Nasu Y, Kumon H, Date I.
    • Journal Title

      Gene Ther

      Volume: 22 Issue: 2 Pages: 146-154

    • DOI

      10.1038/gt.2014.100

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390368, KAKENHI-PROJECT-26670644, KAKENHI-PROJECT-26462182, KAKENHI-PROJECT-25462261, KAKENHI-PROJECT-26293323, KAKENHI-PROJECT-26293352
  • [Journal Article] Significant association of the Axin2 rs2240308 single nucleotide polymorphism with the incidence of prostate cancer.2014

    • Author(s)
      Chao Ma, Chunxiao Liu, Peng Huang, Haruki Kaku, Jie Chen, Kai Guo, Hideo Ueki, Akiko Sakai, Yasutomo Nasu, Hiromi Kumon, Kenji Shimizu, Masami Watanabe.
    • Journal Title

      Oncology Letters

      Volume: 8 Pages: 789-794

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25462479
  • [Journal Article] A novel gene expression system strongly enhances the anticancer effects of a REIC/Dkk-3-encoding adenoviral vector2014

    • Author(s)
      Watanabe M., Sakaguchi M., Kinoshita R., Kaku H., Ariyoshi Y., Ueki H., Tanimoto R., Ebara S., Ochiai K., Futami J., Li SA., Huang P., Nasu Y., Huh NH., Kumon H
    • Journal Title

      Oncology Reports

      Volume: 31巻 Issue: 3 Pages: 1089-95

    • DOI

      10.3892/or.2013.2958

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390382, KAKENHI-PROJECT-24780313, KAKENHI-PROJECT-25462479, KAKENHI-PROJECT-25861425, KAKENHI-PROJECT-26290039
  • [Journal Article] Dramatic Increase in Expression of a Transgene by Insertion of Promoters Downstream of the Cargo Gene2014

    • Author(s)
      Masakiyo Sakaguchi, Masami Watanabe, Rie Kinoshita, Haruki Kaku, Hideo Ueki, Junichiro Futami, Hitoshi Murata, Yusuke Inoue, Shun-Ai Li, Peng Huang, Endy Widya Putranto, I. Made, Winarsa Ruma, Yasutomo Nasu, Hiromi Kumon, Nam-ho Huh
    • Journal Title

      Mol. Biotechnol

      Volume: 56 Issue: 7 Pages: 621-630

    • DOI

      10.1007/s12033-014-9738-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23360370, KAKENHI-PROJECT-24390368, KAKENHI-PROJECT-25460490, KAKENHI-PROJECT-25861425, KAKENHI-PROJECT-26290039
  • [Journal Article] Potential of adenovirus-mediated REIC/Dkk-3 gene therapy for use in the treatment of pancreatic cancer.2014

    • Author(s)
      Uchida D, Shiraha H, Kato H, Nagahara T, Iwamuro M, Kataoka J, Horiguchi S, Watanabe M, Takaki A, Nouso K, Nasu Y, Yagi T, Kumon H, Yamamoto K.
    • Journal Title

      J Gastroenterol Hepatol

      Volume: 29 Issue: 5 Pages: 973-983

    • DOI

      10.1111/jgh.12501

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390368, KAKENHI-PROJECT-24590977, KAKENHI-PROJECT-26293352
  • [Journal Article] Adenovirus-mediated REIC/Dkk-3 gene therapy: Development of an autologous cancer vaccination therapy (Review).2014

    • Author(s)
      Watanabe M, Nasu Y, Kumon H
    • Journal Title

      Oncol Lett

      Volume: 7 Pages: 595-601

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390368
  • [Journal Article] Partial sensitization of human bladder cancer cells to a gene-therapeutic adenovirus carrying REIC/Dkk-3 by downregulation of BRPK/PINK1.2012

    • Author(s)
      Jin Y, Murata H, Sakaguchi M, Kataoka K, Watanabe M, Nasu Y, Kumon H
    • Journal Title

      Huh NH. Oncol Rep.

      Volume: 27(3) Pages: 695-9

    • DOI

      10.3892/or.2011.1543

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390441, KAKENHI-PROJECT-22791473, KAKENHI-PROJECT-23390382, KAKENHI-PROJECT-24390368, KAKENHI-PUBLICLY-24117711
  • [Journal Article] Preclinical Safety and Efficacy of in Situ REIC/Dkk-3 Gene Therapy for Prostate Cancer.2012

    • Author(s)
      Kawauchi K, Watanabe M, Kaku H, Huang P, Sasaki K, Sakaguchi M, Ochiai K, Huh NH, Nasu Y, Kumon H.
    • Journal Title

      Acta Med Okayama

      Volume: 66(1) Pages: 7-16

    • NAID

      120003850603

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390441
  • [Journal Article] Laparoscopic management of complicated urachal remnants in adults2012

    • Author(s)
      Araki M, Saika T, Araki D, Kobayashi Y, Uehara S, Watanabe T, Yamada K, Nasu Y, Kumon H
    • Journal Title

      World J Urol.

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390441
  • [Journal Article] Preoperative positive urine cytology is a risk factor for subsequent development of bladder cancer after nephroureterectomy in patients with upper urinary tract urothelial carcinoma.2011

    • Author(s)
      Kobayashi Y, Saika T, Miyaji Y, Saegusa M, Arata R, Akebi N, Takenaka T, Manabe D, Nasu Y, Kumon H.
    • Journal Title

      World J Urol.

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390441
  • [Journal Article] Tumor suppressor REIC/Dkk-3 interacts with the dynein light chain, Tctex-1.2011

    • Author(s)
      Ochiai K, Watanabe M, Ueki H, Huang P, Fujii Y, Nasu Y, Noguchi H, Hirata T, Sakaguchi M, Huh NH, Kashiwakura Y, Kaku H, Kumon H
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 412(2) Pages: 391-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390441
  • [Journal Article] Could salvage surgery after chemotherapy have clinical impact on cancer survival of patients with metastatic urothelial carcinoma?2011

    • Author(s)
      Bekku K, Saika T, Kobayashi Y, Kioshimoto R, Kanbara T, Nasu Y, Kumon H.
    • Journal Title

      Int J Clin Oncol.

    • NAID

      10031176243

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390441
  • [Journal Article] Advanced two-step transcriptional amplification as a novel method for cancer-specific gene expression and imaging.2011

    • Author(s)
      Watanabe M, Ueki H, Ochiai K, Huang P, Kobayashi Y, Nasu Y, Sasaki K, Kaku H, Kashiwakura Y, Kumon H
    • Journal Title

      Oncol Rep.

      Volume: 26(4) Pages: 769-75

    • DOI

      10.3892/or.2011.1371

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390441, KAKENHI-PROJECT-22791476
  • [Journal Article] Implications of transcriptional factor, OCT-4, in human bladder malignancy and tumor recurrence.2011

    • Author(s)
      Huang P, Chen J, Wang L, Na Y, Kaku H, Ueki H, Sasaki K, Yamaguchi K, Zhang K, Saika T, Nasu Y, Watanabe M, Kumon H
    • Journal Title

      Med Oncol.

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390441
  • [Journal Article] Single nucleotide polymorphism WRN Leu1074Phe is associated with prostate cancer susceptibility in Chinese subjects.2011

    • Author(s)
      Wang L, Kaku H, Huang P, Xu K, Yang K, Zhang J, Li M, Xie L, Wang X, Sakai A, Watanabe M, Nasu Y, Shimizu K, Kumon H, Na Y.
    • Journal Title

      Acta Med Okayama

      Volume: 65(5) Pages: 315-23

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390441
  • [Journal Article] T2-weighted image/T2-weighted image fusion in postimplant dosimetry of prostate brachytherapy.2011

    • Author(s)
      Katayama N, Takemoto M, Yoshio K, Katsui K, Uesugi T, Nasu Y, Matsushita T, Kaji M, Kumon H, Kanazawa S
    • Journal Title

      J Radiat Res

      Volume: 52(5) Pages: 680-4

    • NAID

      10029456187

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390441
  • [Journal Article] Expression pattern of REIC/Dkk-3 in various cell types and the implications of the soluble form in prostatic acinar development.2010

    • Author(s)
      Zhang K, Watanabe M, Kashiwakura Y, Li SA, Edamura K, Huang P, Yamaguchi K, Nasu Y, Kobayashi Y, Sakaguchi M, Ochiai K, Yamada H, Takei K, Ueki H, Huh NH, Li M, Kaku H, Na Y, Kumon H.
    • Journal Title

      Int J Oncol. 37(6)

      Pages: 1495-501

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390426
  • [Journal Article] Potent antitumor effects of combined therapy with a telomerase-specific2010

    • Author(s)
      Huang P, Kaku H, Chen J, Kashiwakura Y, Saika T, Nasu Y, Urata Y, Fujiwara T, Watanabe M, Kumon H
    • Journal Title

      replication-competent adenovirus (OBP-301) and IL-2 in a mouse model of renal cell carcinoma. Cancer Gene Ther

    • Data Source
      KAKENHI-PROJECT-19591851
  • [Journal Article] Down-regulation of BiP/GRP78 sensitizes resistant prostate cancer cells to gene-therapeutic overexpression of REIC/Dkk-3.2010

    • Author(s)
      Tanimoto R, Sakaguchi M, Abarzua F, Kataoka K, Kurose K, Murata H, Nasu Y, Kumon H, Huh NH
    • Journal Title

      Int J Cancer

      Volume: 126(7) Pages: 1562-9

    • NAID

      120004724432

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390441
  • [Journal Article] Down-regulation of BiP/GRP78 sensitizes resistant prostate cancer cells to gene-therapeutic overexpression of REIC/Dkk-3.2010

    • Author(s)
      Tanimoto R, Sakaguchi M, Abarzua F, Kataoka K, Kurose K, Murata H, Nasu Y, Kumon H, Huh NH.
    • Journal Title

      Int J Cancer. 126(7)

      Pages: 1562-1569

    • NAID

      120004724432

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390426
  • [Journal Article] Expression pattern of REIC/Dkk-3 in various cell types and the implications of the soluble form in prostatic acinar development.2010

    • Author(s)
      Zhang K, Watanabe M, Kashiwakura Y, Li SA, Edamura K, Huang P, Yamaguchi K, Nasu Y, Kobayashi Y, Sakaguchi M, Ochiai K, Yamada H, Takei K, Ueki H, Huh NH, Li M, Kaku H, Na Y, Kumon H.
    • Journal Title

      Int J Oncol

      Volume: 37(6) Pages: 1495-501

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390441
  • [Journal Article] A randomized phase II trial of personalized peptide vaccine plus low dose estramustine phosphate(EMP) versus standard dose EMP in patients with castration resistant prostate cancer.2010

    • Author(s)
      Noguchi M, Kakuma T, Uemura H, Nasu Y, Kumon H, Hirao Y, Moriya F, Suekane S, Matsuoka K, Komatsu N, Shichijo S, Yamada A, Itoh K.
    • Journal Title

      Cancer Immunol Immunother.

      Volume: 59(7) Pages: 1001-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390441
  • [Journal Article] Hepatocyte growth factor activator inhibitors(HAI-1 and HAI-2) are potential targets in uterine leiomyosarcoma.2010

    • Author(s)
      Nakamura K, Abarzua F, Hongo A, Kodama J, Nasu Y, Kumon H, Hiramatsu Y.
    • Journal Title

      Int J Oncol

      Volume: 37(3) Pages: 605-14

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390441
  • [Journal Article] Potent antitumor effects of combined therapy with a telomerase-specific, replication-competent adenovirus(OBP-301) and IL-2 in a mouse model of renal cell carcinoma.2010

    • Author(s)
      Huang P, Kaku H, Chen J, Kashiwakura Y, Saika T, Nasu Y, Urata Y, Fujiwara T, Watanabe M, Kumon H.
    • Journal Title

      Cancer Gene Ther.

      Volume: 17(7) Pages: 484-91

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390441
  • [Journal Article] Immunological aspects of REIC/Dkk-3 in monocyte differentiation and tumor regression.2009

    • Author(s)
      Watanabe M, Kashiwakura Y, Huang P, Ochiai K, Futami J, Li SA, Takaoka M, Nasu Y, Sakaguchi M, Huh NH, Kumon H.
    • Journal Title

      Int J Oncol. 34(3)

      Pages: 657-663

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390426
  • [Journal Article] Overexpression of REIC/Dkk-3 in normal fibroblasts suppresses tumor growth via induction of interleukin-7.2009

    • Author(s)
      Sakaguchi M, Kataoka K, Abarzua F, Tanimoto R, Watanabe M, Murata H, Than SS, Kurose K, Kashiwakura Y, Ochiai K, Nasu Y, Kumon H, Huh NH.
    • Journal Title

      J Biol Chem. 284(21)

      Pages: 14236-14244

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390426
  • [Journal Article] A comparison of proteomic profiles changes during 17beta-estradiol treatment in human prostate cancer PC-3 cell line.2009

    • Author(s)
      Chen J, Huang P, Kaku H, Zhang K, Watanabe M, Saika T, Nasu Y, Kumon H
    • Journal Title

      Cancer Genomics Proteomics 6

      Pages: 331-5

    • Data Source
      KAKENHI-PROJECT-19591851
  • [Journal Article] Prospective longitudinal comparative study of health-related quality of life in patients treated with radical prostatectomy or permanent brachytherapy for prostate cancer.2009

    • Author(s)
      Kobuke M, Saika T, Nakanishi Y, Ebara S, Manabe D, Uesugi T, Nose H, Arata R, Tsushima T, Nasu Y, Kumon H
    • Journal Title

      Acta Med Okayama 63(3)

      Pages: 129-35

    • NAID

      120002313130

    • Data Source
      KAKENHI-PROJECT-19591851
  • [Journal Article] REIC/Dkk-3 overexpression downregulates P-glycoprotein in multidrug-resistant MCF7/ADR cells and induces apoptosis in breast cancer.2009

    • Author(s)
      Kawasaki K, Watanabe M, Sakaguchi M, Ogasawara Y, Ochiai K, Nasu Y, Doihara H, Kashiwakura Y, Huh NH, Kumon H, Date H.
    • Journal Title

      Cancer Gene Ther. 16(1)

      Pages: 65-72

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390426
  • [Journal Article] REIC/Dkk-3 stable transfection reduces the malignant phenotype of mouse prostate cancer RM9 cells.2009

    • Author(s)
      Chen J, Watanabe M, Huang P, Sakaguchi M, Ochiai K, Nasu Y, Ouchida M, Huh NH, Shimizu K, Kashiwakura Y, Kaku H, Kumon H.
    • Journal Title

      Int J Mol Med. 24(6)

      Pages: 789-794

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390426
  • [Journal Article] An N-terminal 78 amino acid truncation of REIC/Dkk-3 effectively induces apoptosis.2008

    • Author(s)
      Abarzua F, Kashiwakura Y, Takaoka M, Watanabe M, Ochiai K, Sakaguchi M, Iwawaki T, Tanimoto R, Nasu Y, Huh NH, Kumon H.
    • Journal Title

      Biochem Biophys Res Commun. 375(4)

      Pages: 614-618

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390426
  • [Journal Article] Initial report of hybrid radical prostatectomy for prostate cancer: reduced bleeding, clear vision, and secure surgical margins.2008

    • Author(s)
      Saika T, Kobayashi Y, Watanabe T, Manabe D, Ebara S, Uehara S, Nasu Y, Kumon H
    • Journal Title

      Acta Med Okayama 62(6)

      Pages: 379-84

    • Data Source
      KAKENHI-PROJECT-19591851
  • [Journal Article] Mechanistic Analysis of Resistance to REIC/Dkk-3-induced Apoptosis in Human Bladder Cancer Cells2008

    • Author(s)
      Kobayashi T., Nasu Y
    • Journal Title

      Ada Med Okayama 62

      Pages: 379-384

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390437
  • [Journal Article] Mechanistic analysis of resistance to REIC/Dkk-3-induced apoptosis in human bladder cancer cells.2008

    • Author(s)
      Kobayashi T, Sakaguchi M, Tanimoto R, Abarzua F, Takaishi M, Kaku H, Kataoka K, Saika T, Nasu Y, Miyazaki M, Kumon H, Huh NH.
    • Journal Title

      Acta Med Okayama. 62(6)

      Pages: 393-401

    • NAID

      120002304961

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390426
  • [Journal Article] Direct and distant antitumor effects of a telomerase-selective oncolytic adenoviral agent, OBP-301, in a mouse prostate cancer model.2008

    • Author(s)
      Huang P, Watanabe M, Kaku H, Kashiwakura Y, Chen J, Saika T, Nasu Y, Fujiwara T, Urata Y, Kumon H
    • Journal Title

      Cancer Gene Ther 15(5)

      Pages: 315-22

    • Data Source
      KAKENHI-PROJECT-19591851
  • [Journal Article] Direct and distant antitumor effects of a telomerase-selective oncolytic adenoviral agent, OBP-301, in a mouse prostate cancer model2008

    • Author(s)
      Huang P., Watanabe M., Kaku H., Kashiwakura Y., Chen J., Saika T., Nasu Y., Fujiwara T., Urata Y., Kumon H
    • Journal Title

      Cancer Gene Therapy 15

      Pages: 315-22

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591754
  • [Journal Article] REIC/Dkk-3 overexpression downregulates P-glycoprotein in multidrug-resistant MCF7/ADR cells and induces apoptosis in breast cancer2008

    • Author(s)
      Kawasaki K., Nasu Y
    • Journal Title

      Cancer Gene Therapy 16

      Pages: 65-75

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390437
  • [Journal Article] REIC/Dkk-3overexpression downregulates P-glycoprotein in multidrug-resistant MCF7 /ADR cells and induces apoptosis in breast cancer2008

    • Author(s)
      Kawasaki K., Watanabe M., Sakaguchi M., Ogasawara Y., Ochiai K., Nasu Y., Doihara H., Kashiwakura Y., Huh N-h., Kumon H., Date H.
    • Journal Title

      Cancer Gene Therapy 16

      Pages: 65-75

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390437
  • [Journal Article] An N-terminal 78 amino acid truncation of REIC/Dkk-3 effectively induces apoptosis2008

    • Author(s)
      Abarzua F., Kashiwakura Y., Takaoka M., Watanabe M., Ochiai K., Sakaguchi M., Iwawaki T., Tanimoto R., Nasu Y., Huh NH., Kumon H.
    • Journal Title

      Biochem Biophys Res Commun 375

      Pages: 614-618

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390437
  • [Journal Article] An N-terninal 78 amino acid truncation of REIC/Dkk-3 effect ively induces apoptosis2008

    • Author(s)
      Abarzua F., Nasu Y
    • Journal Title

      Biochem Biophys Res Commun 375

      Pages: 614-618

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390437
  • [Journal Article] N-h.Mechanistic Analysis of Resistance to REIC/Dkk-3-induced Apoptosis in Human Bladder Cancer Cells2008

    • Author(s)
      Kobayashi, T., Sakaguchi M., Tanimoto R., Abarzua, F., Takaishi M., Kaku, H. Kataoka, , K., Saika T.,Nasu Y., Miyazaki M., Kumon H., Huh
    • Journal Title

      Acta Med Okayama 62

      Pages: 379-384

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390437
  • [Journal Article] Iodine-125 seed impla(permanent brachytherapy) for clinically localized prostate cancer.2008

    • Author(s)
      Ebara S, Katayama N, Tanimoto R, Edamura K, Nose H, Manabe D, Kobayashi T, Kobayashi Y, Kobuke M, Takemoto M, Saika T, Nasu Y, Kanazawa S, Kumon H
    • Journal Title

      Acta Med Okayama 62(1)

      Pages: 9-13

    • Data Source
      KAKENHI-PROJECT-19591851
  • [Journal Article] Down-regulation of inhibition of differentiation-1 via activation of activating transcription factor 3 and Smad regulates REIC/Dickkopf-3-induced apoptosis.2008

    • Author(s)
      Kashiwakura Y, Ochiai K, Watanabe M, Abarzua F, Sakaguchi M, Takaoka M, Tanimoto R, Nasu Y, Huh NH, Kumon H.
    • Journal Title

      Cancer Res. 68(20)

      Pages: 8333-8341

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390426
  • [Journal Article] REIC/Dkk-3 as a potential gene therapeutic agent against human testicular cancer2007

    • Author(s)
      Tanimoto R. Abarzua F, Sakaguchi M, Takaishi M, Nasu Y, Kumon H, Huh NH
    • Journal Title

      Int J Mol Med 19

      Pages: 363-368

    • NAID

      10019918537

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390437
  • [Journal Article] 岡山大学における前立腺癌遺伝子治療研究の現況と展望 -ベーシックリサーチからトランスレーショナルリサーチへ-2007

    • Author(s)
      賀来春紀, 藤原俊義, 渡部昌実, 黄鵬, 陳潔, 谷本竜太 フェルナンド アバルスア, 枝村康平 真鍋大輔, 江原伸, 雑賀隆史 那須保友, 公文裕巳
    • Journal Title

      西日本泌尿器科 69

      Pages: 221-229

    • NAID

      10019994587

    • Data Source
      KAKENHI-PROJECT-17659505
  • [Journal Article] 前立腺癌-基礎・臨床研究のアップデート-II.臨床研究 治療 遺伝子治療自殺遺伝子・サイトカイン遺伝子を用いた遺伝子治療2007

    • Author(s)
      賀来春紀, 那須保友, 雑賀隆史, 公文裕巳
    • Journal Title

      日本臨牀 65

      Pages: 522-527

    • Data Source
      KAKENHI-PROJECT-18390437
  • [Journal Article] Heat shock proteins play a crucial role in tumor-specific apoptosis by REIC/Dkk-32007

    • Author(s)
      Abarzua F., Sakaguchi M., TaniSonegawa H., Li D.W., Edamura K., Kobayashi T., Watanabe M., Kashiwakura Y., Kaku H., Saika T., Nakamura K., Nasu Y., Kumon H., Huh NH
    • Journal Title

      Int J Mol Med. 20

      Pages: 37-43

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591754
  • [Journal Article] Adenovirus-mediated REIC/Dkk-3 gene transfer inhibits tumor growth and metastasis in an orthotopic prostate cancer model2007

    • Author(s)
      Edamura K, Nasu Y, Takaishi M, Kobayashi T, Abarzua F, Sakaguchi M, Kashiwakura Y, Ebara S, Saika T, Watanabe M, Huh N.H, Kumon H
    • Journal Title

      Cancer Gene Ther 14

      Pages: 765-772

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17659505
  • [Journal Article] Suicide gene therapy with adenoviral delivery of HSV-tK gene for patients withlocal recurrence of prostate cancer after hormonal therapy2007

    • Author(s)
      Nasu Y., Saika T., Ebara S., Kusaka N., Kaku H., Abarzua F., Manabe D., Thompson T.C.,Kumon H
    • Journal Title

      Mol Ther. 15

      Pages: 834-840

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591754
  • [Journal Article] REIC/Dkk-3 as a potential gene therapeutic agent against human testicular cancer2007

    • Author(s)
      Tanimoto R, Abarzua F, Sakaguchi M, Takaishi M, Nasu Y, Kumon H, Huh NH
    • Journal Title

      Int J Mol Med. 19

      Pages: 363-368

    • NAID

      10019918537

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390437
  • [Journal Article] REIC/Dkk-3 as a potential gene therapeutic agent against human testicular cancer2007

    • Author(s)
      Tanimoto R, Nasu Y et al.
    • Journal Title

      Int J Mol Med 19

      Pages: 363-8

    • NAID

      10019918537

    • Data Source
      KAKENHI-PROJECT-18390437
  • [Journal Article] REIC/Dkk-3 as a potential gene therapeutic agent against human testicular cancer2007

    • Author(s)
      Tanimoto R, Nasu Y, et al.
    • Journal Title

      Int J Mol Med 19

      Pages: 363-368

    • NAID

      10019918537

    • Data Source
      KAKENHI-PROJECT-17659505
  • [Journal Article] Heat shock proteins play a crucial role in tumor-specific apoptosis by REIC/Dkk-32007

    • Author(s)
      Abarzua F, Sakaguchi M, Tanimoto R, Sonegawa H, Li DW, Edamura K, Kobayashi T, Watanabe M, Kashiwakura Y, Kaku H, Saika T, Nakamura K, Nasu Y, Kumon H, Huh NH
    • Journal Title

      Int J Mol Med. 20

      Pages: 37-43

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390437
  • [Journal Article] Suicide gene therapy with adenoviral delivery of HSV-tK gene for patients with local recurrence of prostate cancer after hormonal therapy2007

    • Author(s)
      Nasu Y, Saika T, Ebara S, Kusaka N, Kaku H, Abarzua F, Manabe D, Thompson T.C, Kumon H
    • Journal Title

      Mol Ther 15

      Pages: 834-840

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390437
  • [Journal Article] Suicide gene therapy with adenoviral delivery of HSV-tK gene for patients withlocal recurrence of prostate cancer after hormonal therapy2007

    • Author(s)
      Nasu Y, Saika T, Ebara S, Kusaka N, Kaku H, Abarzua F, Manabe D, Thompson T.C, Kumon H
    • Journal Title

      Mol Ther. 15

      Pages: 834-840

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390437
  • [Journal Article] Heat shock proteins play a crucial role in tumor-specific apoptosis by REIC/Dkk-3.2007

    • Author(s)
      Abarzua F, Sakaguchi M, Tanimoto R, Sonegawa H, Li DW, Edamura K, Kobayashi T, Watanabe M, Kashiwakura Y, Kaku H, Saika T, Nakamura K, Nasu Y, Kumon H, Huh NH
    • Journal Title

      Int J Mol Med 20(1)

      Pages: 37-43

    • Data Source
      KAKENHI-PROJECT-19591851
  • [Journal Article] Suicide gene therapy with adenoviral delivery of HSV-tK gene for patients with local recurrence of prostate cancer after hormonal therapy2007

    • Author(s)
      Nasu Y, Saika T, Ebara S, Kusaka N, Kaku H, Abarzua F, Manabe D, Thompson T.C, Kumon H
    • Journal Title

      Mol Ther 15

      Pages: 834-840

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17659505
  • [Journal Article] Suicide gene therapy with adenoviral vector delivery of HSV-tk gene and the intravenous administration of ganciclovir for patients with local recurrence of prostate cancer after hormonal therapy2007

    • Author(s)
      Nasu Y, Saika T, et al.
    • Journal Title

      Molecular Therapy (In press)

    • NAID

      130004505632

    • Data Source
      KAKENHI-PROJECT-17659505
  • [Journal Article] Adenovirus-mediated REIC/Dkk-3 gene transfer inhibits tumor growth and metastasis in an orthotopic prostate cancer model2007

    • Author(s)
      Edamura K, Nasu Y, Takaishi M, Kobayashi T, Abarzua F, Sakaguchi M, Kashiwakura Y, Ebara S, Saika T, Watanabe M, Huh N.H. Kumon H
    • Journal Title

      Cancer Gene Ther 14

      Pages: 765-772

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390437
  • [Journal Article] Suicide gene therapy with adenoviral delivery of HSV-tK gene for patients with local recurrence of prostate cancer after hormonal therapy.2007

    • Author(s)
      Nasu Y, Saika T, Ebara S, Kusaka N, Kaku H, Abarzua F, Manabe D, Thompson TC, Kumon H
    • Journal Title

      Mol Ther 15(4)

      Pages: 834-40

    • Data Source
      KAKENHI-PROJECT-19591851
  • [Journal Article] Suicide gene therapy with adenoviral vector delivery of HSV-tk gene and the intravnous administration of ganciclovir for patients with local recurrence of prostate cancer after hormonal therapy2007

    • Author(s)
      Nasu Y, Saika T et al.
    • Journal Title

      Molecular Therapy (In press)

    • Data Source
      KAKENHI-PROJECT-18390437
  • [Journal Article] Heat shock proteins play a crucial role in tumor-specific apoptosis by REIC/Dkk-32007

    • Author(s)
      Abarzua F, Nasu Y et al.
    • Journal Title

      Int J Mol Med (In press)

    • Data Source
      KAKENHI-PROJECT-18390437
  • [Journal Article] Heat shock proteins play a crucial role in tumor-specific apoptosis by REIC/Dkk-32007

    • Author(s)
      Abarzua F, Nasu Y, et al.
    • Journal Title

      Int J Mol Med (In press)

    • Data Source
      KAKENHI-PROJECT-17659505
  • [Journal Article] Adenovirus-mediated REIC/Dkk-3 gene transfer inhibits tumor growth and metastasis in an orthotopic prostate cancer model.2007

    • Author(s)
      Edamura K, Nasu Y, Takaishi M, Kobayashi T, Abarzua F, Sakaguchi M, Kashiwakura Y, Ebara S, Saika T, Watanabe M, Huh NH, Kumon H
    • Journal Title

      Cancer Gene Ther 14(9)

      Pages: 765-72

    • Data Source
      KAKENHI-PROJECT-19591851
  • [Journal Article] Adenovirus-mediated REIC/Dkk-3 gene transfer inhibits tumo growth and metastasis in an orthotopic prostate cancer model2007

    • Author(s)
      Edamura K, Nasu Y, Takaishi M, Kobayashi T, Abarzua F, Sakaguchi M, Kashiwakura Y, Ebara S, Saika T, Watanabe M, Huh NH, Kumon H
    • Journal Title

      Cancer Gene Ther. 14

      Pages: 765-772

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390437
  • [Journal Article] Routine transurethral biopsy of the bladder is not necessary to evaluate the response to bacilluscalmette-guerin therapy2007

    • Author(s)
      Murakami T., Ebara S., Saika T., Irie S., Takeda K., Maki Y., Miyaji S., Manabe D., Kaku H., Nasu Y., Tsushima T., Kumon H
    • Journal Title

      Acta Med Okayama 61

      Pages: 341-344

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591754
  • [Journal Article] 前立腺癌-基礎・臨床研究のアップデート-II.臨床研究 治療 遺伝子治療2007

    • Author(s)
      賀来春紀, 那須保友, 雑賀隆史, 公文裕巳
    • Journal Title

      自殺遺伝子・サイトカイン遺伝子を用いた遺伝子治療 65

      Pages: 522-527

    • Data Source
      KAKENHI-PROJECT-18591754
  • [Journal Article] Combination chemotherapy with estramustine phosphate, ifosand cisplatin for hormone-refractory prostate cancer2006

    • Author(s)
      Kaku H., Saika T., Tsushima T., Nagai A., Yokoyama T., Abarzua F., Ebara S., Manabe D., Nasu Y., Kumon H
    • Journal Title

      Acta Med Okayama 60

      Pages: 43-49

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591754
  • [Journal Article] 岡山大学における前立腺癌遺伝子治療研究の現況と展望-ベーシックリサーチからトランスレーショナルリサーチヘー2006

    • Author(s)
      賀来春紀, 藤原俊義, 公文裕巳, 渡部昌実, 黄鵬, 陳 潔, 谷本竜太, フェルナンド アバルスア, 枝村康平, 真鍋大輔, 江原 伸, 雑賀隆史, 那須保友, 公文裕巳
    • Journal Title

      西日本泌尿器科 69

      Pages: 221-229

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591754
  • [Journal Article] Induction of cell death in human papilomavirus 18-positive cervical cancer cells by E6 siRNA2006

    • Author(s)
      K.Yamato, Y.Nasu et al.
    • Journal Title

      Cancer Gene Therapy 13

      Pages: 234-241

    • Data Source
      KAKENHI-PROJECT-15390491
  • [Journal Article] Induction of cell death in human papillomavirus 18-positive cervical cancer cells by E6 siRNA.2006

    • Author(s)
      K.Yamato, Y.Nasu et al.
    • Journal Title

      Cancer Gene Therapy 13

      Pages: 234-241

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390491
  • [Journal Article] Hepsin shows inhibitory effects through apoptotic pathway on ovarian cancer cell lines2006

    • Author(s)
      K.Nakamura, Y.Nasu, H.Kumon
    • Journal Title

      International Journal of Oncology 28

      Pages: 393-398

    • Data Source
      KAKENHI-PROJECT-15390491
  • [Journal Article] 前立腺癌の遺伝子治療2005

    • Author(s)
      那須保友, 公文裕巳
    • Journal Title

      日本臨床 63

      Pages: 335-338

    • Data Source
      KAKENHI-PROJECT-15209052
  • [Journal Article] Adenovirus-mediated overexpression of REIC/Dkk-3 selectively induces apoptosis in human prostate cancer cells through activation of JNK.2005

    • Author(s)
      F.Abarzua, Y.Nasu, H.Kumon et al.
    • Journal Title

      Cancer Research 65

      Pages: 9617-9622

    • Data Source
      KAKENHI-PROJECT-15390491
  • [Journal Article] Adeno-Associated Virus 2-Mediated intratumoral prostate cancer gene therapy : Long-term maspin expression efficiently suppresses tumor growth.2005

    • Author(s)
      Watanabe M., Nasu Y., Kashiwakura Y., Kusumi N., Tamayose K., Nagai A., Sasano T., Shimada T., Daida H., Kumon H.
    • Journal Title

      Human Gene Therapy 16

      Pages: 699-710

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15209052
  • [Journal Article] Adeno-Associated Virus 2-Mediated Intratumoral Prostate Cancer Gene Therapy : Long-Term Maspin Expression Efficiently Suppresses Tumor Growth2005

    • Author(s)
      M.Watanabe, Y.Nasu, H.Kumon et al.
    • Journal Title

      Human Gene Therapy 16

      Pages: 699-710

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390491
  • [Journal Article] 前立腺癌の遺伝子治療2005

    • Author(s)
      那須保友, 公文裕巳
    • Journal Title

      日本臨床 63(2)

      Pages: 335-338

    • Data Source
      KAKENHI-PROJECT-15209052
  • [Journal Article] XAGE-1 mRNA expression in prostate cancer and antibody response in patients.2005

    • Author(s)
      Koicumi F., Noguchi Y., Saika T., Nakagawa K., Sato S., Eldib A.M.A., Nasu Y., Kumon H., Nakayama E.
    • Journal Title

      Microbiol Immunol. 49(5)

      Pages: 471-476

    • NAID

      10015708346

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15209052
  • [Journal Article] Adenovirus-mediated overexpression of REIC/Dkk-3 selectively induces apoptosis in human prostate cancer cells through activation of JNK.2005

    • Author(s)
      F.Abarzua, Y.Nasu, H.Kumon et al.
    • Journal Title

      Cancer Research 65

      Pages: 9617-9622

    • Data Source
      KAKENHI-PROJECT-15209052
  • [Journal Article] Adenovirus-mediated overexpression of REIC/Dkk-3 selectively induces apoptosis in human prostate cancer cells through activation of JNK.2005

    • Author(s)
      F.Abarzua, Y, Nasu, H.Kumon et al.
    • Journal Title

      Cancer Research 65

      Pages: 9617-9622

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390491
  • [Journal Article] Adenovirus-mediated overexpression of REIC/Dkk-3 selectively induces apoptosis in human prostate cancer cells through activation of c-Jun-NH2-Kinase.2005

    • Author(s)
      Abarzua F., Nasu Y., Kumon H.
    • Journal Title

      Cancer Research 65(21)

      Pages: 9617-9622

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15209052
  • [Journal Article] Adeno-Associated Virus 2-Mediated Intratumoral prostate Cancer Gene Therapy : Long-Term Maspin Expression Efficiently Suppresses Tumor Growth.2005

    • Author(s)
      M.Watanabe, Y.Nasu, H.Kumon et al.
    • Journal Title

      Human Gene Therapy 16

      Pages: 699-710

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390491
  • [Journal Article] Adeno-Associated Virus 2-Mediated intratumoral prostate cancer gene therapy : Long-term maspin expression efficiently suppresses tumor growth.2005

    • Author(s)
      Watanabe M., Nasu Y., Kumon H
    • Journal Title

      Human Gene Therapy 16

      Pages: 699-710

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15209052
  • [Journal Article] 前立腺癌の遺伝子治療2005

    • Author(s)
      那須保友, 公文裕巳
    • Journal Title

      日本臨床 63(2)

      Pages: 335-338

    • Data Source
      KAKENHI-PROJECT-15390491
  • [Journal Article] Adenovirus-mediated overexpression of REIC/Dkk-3 selectively induces apoptosis in human prostate cancer cells through activation of c-Jun-NH2-Kinase.2005

    • Author(s)
      Abarzua F., Sakaguchi M., Takaishi M., Nasu Y., Kurose K., Ebara S., Miyazaki M., Namba M., Kumon H., Huh Nam-ho.
    • Journal Title

      Cancer Research 65(21)

      Pages: 9617-9622

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15209052
  • [Journal Article] Adeno-Associated Virus 2-Mediated Intratumoral Prostate Cancer Gene Therapy : Long-Term Maspin Expression Efficiently Suppresses Tumor Growth2005

    • Author(s)
      M.Watanabe, Y.Nasu, H.Kumon et al.
    • Journal Title

      Human Gene Therapy 16

      Pages: 699-710

    • Data Source
      KAKENHI-PROJECT-15209052
  • [Journal Article] Decreased Expression of REIC/Dkk-3 in Human Renal Clear Cell carcinoma.2004

    • Author(s)
      K.Kurose, Y.Nasu, H.Kumon et al.
    • Journal Title

      Journal of Urology 171

      Pages: 1314-1318

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390491
  • [Journal Article] Interleukin-12による前立腺癌に対する新しい遺伝子治療の試み2004

    • Author(s)
      那須保友, 江原 伸, 公文裕巳
    • Journal Title

      日本臨床 62(6)

      Pages: 1181-1191

    • Data Source
      KAKENHI-PROJECT-15390491
  • [Journal Article] Decreased Expression of REIC/Dkk-3 in Human Renal Clear Cell Carcinoma.2004

    • Author(s)
      K.Kurose, Y.Nasu, H.Kumon et al.
    • Journal Title

      Jouranal of Urology 171

      Pages: 1314-1318

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390491
  • [Journal Article] Interleukin-12による前立腺癌に対する新しい遺伝子治療の試み2004

    • Author(s)
      那須保友, 江原 伸, 公文裕巳
    • Journal Title

      日本臨床 62(6)

      Pages: 1181-1191

    • Data Source
      KAKENHI-PROJECT-15209052
  • [Journal Article] NY-ESO-1 mRNA expression and immunogenicity in advanced prostate cancer.2003

    • Author(s)
      T.Nakada, Y.Nasu, H.Kumon
    • Journal Title

      Cancer Immunity 3

      Pages: 10-15

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390491
  • [Journal Article] NY-ESO-1 mRNA expression and immunogenicity in advanced prostate cancer.2003

    • Author(s)
      Nakada T., Noguchi Y., Satoh S., Ono T., Saika T., Kurashige T., Gnjatic S., Ritter G., Chen Y-T., Stockert E., Nasu Y., Tsushima T., Kumon H., Old L.J., Nakayama E.
    • Journal Title

      Cancer Immunity 3

      Pages: 10-21

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15209052
  • [Journal Article] Y-ES0-1 mRNA expresslon and immunogenicity in advanced prostate cancer.2003

    • Author(s)
      T.Nakada, Y.Nasu, H.Kumon
    • Journal Title

      Cancer Immunity 3

      Pages: 10-15

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390491
  • [Journal Article] Adeno-Associated Virus 2-Mediated Intratumoral Prostate Cancer Gene Therapy : Long-Term Maspin Expression Efficiently Suppresses Tumor Growth

    • Author(s)
      M.Watanabe, Y.Nasu, H.Kumon
    • Journal Title

      Human Gene Therapy (in press)

    • Data Source
      KAKENHI-PROJECT-15209052
  • [Journal Article] Adeno-Associated Virus 2-Mediated Intratumoral Prostate Cancer Gene Therapy : Long-Term Maspin Expression Efficiently Suppresses Tumor Growth

    • Author(s)
      M.Watanabe, Y.Nasu, H.Kumon
    • Journal Title

      Human Gene Therapy (in press)

    • Data Source
      KAKENHI-PROJECT-15390491
  • [Patent] REIC遺伝子を発現する制限増殖型アデノウイルス2014

    • Inventor(s)
      公文裕巳、那須保友、渡部昌実、ユン チェオク
    • Industrial Property Rights Holder
      岡山大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2014-110672
    • Filing Date
      2014-05-28
    • Data Source
      KAKENHI-PROJECT-24390368
  • [Patent] 新規悪性中皮腫治療剤及び免疫賦活化剤2008

    • Inventor(s)
      公文裕巳、那須保友、渡部昌実、柏倉祐司
    • Industrial Property Rights Holder
      岡山大学、桃太郎源(株)
    • Filing Date
      2008-07-30
    • Data Source
      KAKENHI-PROJECT-20390426
  • [Patent] 抗癌剤耐性癌において抗癌剤増強作用を有する癌細胞死誘導剤2007

    • Inventor(s)
      公文裕巳、那須保友、渡部昌実、柏倉祐司、川崎賢祐
    • Industrial Property Rights Holder
      国立大学法人岡山大学、桃太郎源株式会社産業財産権の種類
    • Industrial Property Number
      2007-287373
    • Filing Date
      2007-11-05
    • Data Source
      KAKENHI-PROJECT-18390437
  • [Patent] 前立腺癌細胞のアポトーシス誘発剤2005

    • Inventor(s)
      公文 裕巳, 那須 保友, 許 南浩, 阪口 正清
    • Industrial Property Rights Holder
      公文 裕巳, 那須 保友, 許 南浩, 阪口 正清
    • Industrial Property Number
      2005-073807
    • Filing Date
      2005
    • Data Source
      KAKENHI-PROJECT-15390491
  • [Patent] 前立腺癌細胞のアポトーシス誘発剤2005

    • Inventor(s)
      公文裕巳, 那須保友, 許 南浩, 阪口正清
    • Industrial Property Rights Holder
      公文裕巳, 那須保友, 許 南浩, 阪口正清
    • Industrial Property Number
      2005-073807
    • Filing Date
      2005
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390491
  • [Presentation] Nitroxoline inhibits bladder cancer progression by reversing epithelial-to-mesenchymal transition process2019

    • Author(s)
      Wenfeng Lin, Naijin Xu, Chunxiao Liu, Yasutomo Nasu, Peng Huang
    • Organizer
      Best-ASCO 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11138
  • [Presentation] Glaucocalyxin A, a potential anti-cancer agent, inhibits bladder cancer progression in vitro and in vivo via the PI3K/Akt pathway2019

    • Author(s)
      Naijin Xu, Wenfeng Lin,Yasutomo Nasu, Peng Huang
    • Organizer
      Best-ASCO 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11138
  • [Presentation] A novel nitroxoline treatment, targeting the PI3K pathway, in combination with PD-1 blockage, exerts a potent prostate cancer anti-tumor effect2018

    • Author(s)
      Naijin Xu , Chaoming Li , Abai Xu , Chunxiao Liu , Qiang Li , Masami Watanabe , Motoo Araki , Koichiro Wada Yasutomo Nasu, Peng Huang
    • Organizer
      AUA2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11138
  • [Presentation] Induction of prostate cancer stem cell properties in mouse induced pluripotent stem cells via conditioned medium and tracking drug response2018

    • Author(s)
      Peng Huang, Naijin Xu, Masami Watanabe, Yasutomo Nasu
    • Organizer
      JSGT2018
    • Data Source
      KAKENHI-PROJECT-17K11138
  • [Presentation] Programmed death ligand 1 expression in bladder RMS (rhabdomyosarcoma) and its association with clinicopathological features2018

    • Author(s)
      Peng Huang, Peng Xu, Naijin Xu, Xiezhao Li, Masami Watanabe, Chunxiao Liu and Yasutomo Nasu
    • Organizer
      AUA2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11138
  • [Presentation] Prostate cancer precision immunotherapy2018

    • Author(s)
      peng huang, Motoo Araki, Ichiro Tsuboi, Tomohiro Hongo, yasutomo Nasu
    • Organizer
      2018 Pearl River Urology Hi-Tec Forum
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11138
  • [Presentation] Monitoring preclinical cancer models: Multilateral evaluation of innovating the discovery of therapeutics2018

    • Author(s)
      Peng Huang, Peng Xu, Naijin Xu, Xiezhao Li, Masami Watanabe, Chunxiao Liu and Yasutomo Nasu
    • Organizer
      Third AACR-SNMMI Joint Conference 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11138
  • [Presentation] INDUCTION OF PROSTATE CANCER STEM CELL PROPERTIES IN MOUSE INDUCED PLURIPOTENT STEM CELLS VIA DEFINED CARCINOMA NICHE AND TRACKING DRUG RESPONSE IN PRECLINICAL RESEARCH2017

    • Author(s)
      Naijin Xu、Xiezhao Li、Abai Xu、Masami Watanabe、Peng Huang、Yasutomo Nasu、Chunxiao Liu
    • Organizer
      AUA2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11138
  • [Presentation] IMMUNE CHECKPOINT INHIBITOR COMBINED WITH THE GROWTH INHIBITOR LYCORINE SYNERGISTICALLY FUNCTION TO MEDIATE ANTI-TUMOR EFFECTS IN A MOUSE MODEL OF RENAL CELL CARCINOMA2017

    • Author(s)
      Xiezhao Li、Naijin Xu、Abai Xu、Masami Watanabe、Peng Huang、Yasutomo Nasu、Chunxiao Liu
    • Organizer
      AUA2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11138
  • [Presentation] REAL-TIME MONITORING OF TUMOR PROGRESSION AND DRUG RESPONSES IN A PRECLINICAL MOUSE MODEL OF PROSTATE CANCER2017

    • Author(s)
      Peng Huang、Naijin Xu、Xiezhao Li、Abai Xu、Masami Watanabe、Yasutomo Nasu、Chunxiao Liu
    • Organizer
      AUA2017
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K11138
  • [Presentation] Real-time monitoring of tumor progression and drug responses in a preclinical mouse model of prostate cancer2016

    • Author(s)
      Peng Huang , Naijin Xu, Eiji Matsuura, Chunxiao Liu , Masami Watanabe, Hiromi Kumon  and Yasutomo Nasu
    • Organizer
      International Society for Cell and Gene Therapy of Cancer 2016
    • Place of Presentation
      seoul, Korea
    • Year and Date
      2016-11-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K20093
  • [Presentation] Real-time monitoring of tumor progression and drug responses in a preclinical mouse model of prostate cancer2016

    • Author(s)
      Naijin Xu, Peng Huang , Eiji Matsuura, Chunxiao Liu , Masami Watanabe, Hiromi Kumon  and Yasutomo Nasu
    • Organizer
      Best ofASCO (The Singapore Scoiety of Oncology 2016)
    • Place of Presentation
      Singapore
    • Year and Date
      2016-07-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K20093
  • [Presentation] Monitoring and imaging tumor progression and tracking drug response in a preclinical mouse model2016

    • Author(s)
      Peng Huang , Naijin Xu, Eiji Matsuura, Chunxiao Liu , Masami Watanabe, Hiromi Kumon  and Yasutomo Nasu
    • Organizer
      22nd Annual Meeting of Japan Society of Gene and Cell Therapy
    • Place of Presentation
      Tokyo
    • Year and Date
      2016-07-28
    • Data Source
      KAKENHI-PROJECT-15K20093
  • [Presentation] The proof of concept of REIC/Dkk-3 gene therapy for thoracic malignancies2016

    • Author(s)
      Shinichi Toyooka, Ken Suzawa, Kazuhiko Shien, Masakiyo Sakaguchi, Masami Watanabe, Peng Huang, Kei Namba, Hidejiro Torigoe, Hiroki Sato, Junichi Soh, Hiromasa Yamamoto, Yuho Maki, Kazunori Tsukuda, Shuta Tomida, Yasutomo Nasu, Hiromi Kumon, Shinichiro Miyoshi.
    • Organizer
      Tenth AACR-JCA Joint Conference
    • Place of Presentation
      Maui USA
    • Year and Date
      2016-02-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K20093
  • [Presentation] The efficacy of REIC/Dkk-3 gene therapy for pancreatic cancer2014

    • Author(s)
      内田大輔、白羽英則、加藤博也、永原照也、岩室雅也、片岡淳朗、堀口繁、渡部昌美、高木章乃夫、能祖一裕、那須保友、八木孝仁、公文裕巳、山本和秀
    • Organizer
      Digestive Disease Week 2014
    • Place of Presentation
      シカゴ(米国)
    • Data Source
      KAKENHI-PROJECT-24590977
  • [Presentation] REIC/Dkk-3遺伝子導入による膵癌治療の検討2013

    • Author(s)
      内田大輔、白羽英則、加藤博也、永原照也、片岡淳郎、岩室雅也、堀口繁、堤 康一郎、渡部昌実、那須保友、公文裕巳、山本和秀
    • Organizer
      日本すい臓学会大会
    • Place of Presentation
      仙台国際センター
    • Data Source
      KAKENHI-PROJECT-24590977
  • [Presentation] REIC/Dkk-3遺伝子導入による膵癌治療の検討2013

    • Author(s)
      内田大輔、白羽英則、加藤博也、永原照也、片岡淳郎、岩室雅也、堀口繁、堤 康一郎、渡部昌実、那須保友、公文裕巳、山本和秀
    • Organizer
      第44回 日本膵臓学会大会
    • Place of Presentation
      仙台国際センター(仙台市)
    • Data Source
      KAKENHI-PROJECT-24590977
  • [Presentation] Prostate Cancer Gene. Therapy in Japan2012

    • Author(s)
      Nasu Y,
    • Organizer
      European Society of Gene&Cell Therapy
    • Place of Presentation
      Versai1les, France(招待講演)
    • Year and Date
      2012-10-25
    • Data Source
      KAKENHI-PROJECT-24390368
  • [Presentation] Symposium A global gene therapy renaissance Prostate cancer gene therapy in Japan-from HSV-tk to REIC/Dkk-32010

    • Author(s)
      Nasu Y
    • Organizer
      American Society of Gene&Cell Therapy 13th Annual Meetings
    • Place of Presentation
      Washington, DC, USA
    • Data Source
      KAKENHI-PROJECT-21390441
  • [Presentation] In situ gene therapy for prostate cancer-its local and systemic effect-2009

    • Author(s)
      那須保友
    • Organizer
      日本遺伝子治療学会
    • Place of Presentation
      大阪
    • Year and Date
      2009-07-09
    • Data Source
      KAKENHI-PROJECT-21390441
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    # of Collaborated Products: 6 results
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    # of Collaborated Products: 3 results
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    # of Collaborated Products: 61 results
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    # of Collaborated Projects: 7 results
    # of Collaborated Products: 21 results
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    # of Collaborated Products: 16 results
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    # of Collaborated Projects: 5 results
    # of Collaborated Products: 1 results
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    # of Collaborated Projects: 5 results
    # of Collaborated Products: 23 results
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    # of Collaborated Projects: 3 results
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    # of Collaborated Products: 1 results
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    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 2 results
    # of Collaborated Products: 20 results
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    # of Collaborated Projects: 2 results
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    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
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    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
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    # of Collaborated Products: 3 results
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    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
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    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
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    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 20.  WATANABE MASAMI (70444677)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 7 results
  • 21.  Kobayashi Yasuyuki (50366027)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 10 results
  • 24.  TSUTSUI Ken (70108158)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 26.  YOSHINOUCHI Mitsuo (50261235)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
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    # of Collaborated Products: 0 results
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    # of Collaborated Products: 0 results
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    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
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    # of Collaborated Projects: 1 results
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    # of Collaborated Projects: 1 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 1 results
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