Hirota Kazuyoshi 廣田和美

… Alternative Names

Researcher Number	20238413
Other IDs
External Links
Affiliation (Current)	2021: 弘前大学, 医学研究科, 教授
Affiliation (based on the past Project Information) *help	2016 – 2021: 弘前大学, 医学研究科, 教授 2011 – 2015: 弘前大学, 医学(系)研究科(研究院), 教授 2013: 弘前大学, 医学研究科, 教授 2007 – 2011: Hirosaki University, Hirosaki University, Graduate School of Medicine, Professor 2004 – 2006: Hirosaki University, School of Medicine, Professor, 医学部, 教授 … More
Review Section/Research Field	Principal Investigator Anesthesiology/Resuscitation studies / Anesthesiology/Resuscitation studies / Anesthesiology / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Basic Section 55050:Anesthesiology-related Except Principal Investigator Anesthesiology/Resuscitation studies / Basic Section 55050:Anesthesiology-related / Anesthesiology / Fundamental nursing / Anesthesiology/Resuscitation studies
Keywords	Principal Investigator ラット / 大脳皮質 / ノルエピネフリン / ノルアドレナリン / オレキシン / 気管支鏡 / 神経伝達物質 / 麻酔 / 神経生理活性物質 / GABA_A受容体 … More Except Principal Investigator 睡眠 / 全身麻酔 / 脳波 / 内因性睡眠物質 / 脳・神経 / 麻酔 / 覚醒 / 睡眠障害 / オレキシン / ノルアドレナリン / 全身麻酔薬 / Sleep / α_1レセプター / 視索前野 / 低体温 / マッサージ / 症状緩和 / リンパ浮腫 / 唾液中biomarkers / 唾液中バイオマーカー / STAI-s / 唾液中α-Amylase濃度 / 唾液中CgA濃度 / 唾液中sIgA濃度 / STAI / 麻酔学 / 麻酔の質 / 麻酔科学 / 内因性NPS / 麻酔・手術後の睡眠、認知障害 / ノンレム睡眠 / レム睡眠 / 内因性覚醒物質 / MCH / 鎮痛 / 麻酔時間 / ERAS / 生理睡眠物質 / General anesthetic agents / Noradrenaline / Sleep Related Substance / ラット / サイトカイン / General anesthetics / EEG / Rat / Cytokine / 周術期管理 / 術後アウトカム / うつ病 / ケタミン / In vivo Ca2+ イメージング / オプトジェネティクス / セル・アセンブリ / In vivo Ca2+イメージング / 局所麻酔薬 / 自律神経機能 / 炎症反応 Less

Clinical study for preoperative prediction of depression in older adult patients by deep learning and basic study for clarifying mechanism of depression and developing its prophylaxis.Principal Investigator
- Principal Investigator
  
  廣田和美
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Hirosaki University
バーチャルリアリティを用いたプレハビリテーションプログラムによる術後譫妄予防Principal Investigator
- Principal Investigator
  
  廣田和美
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Hirosaki University
うつ病病態発現神経回路の解明とケタミン抗うつ作用機序の検討
- Principal Investigator
  
  二階堂義和
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Hirosaki University
ストレスコントロールを指向した周術期管理法の探求～局所麻酔薬の有用性～
- Principal Investigator
  
  北山眞任
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Hirosaki University
術後アウトカム指向麻酔法の探求：内因性睡眠物質を応用した円滑な周術期管理への道標
- Principal Investigator
  
  櫛方哲也
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Hirosaki University
Investigation of mechanism of pathogenesis of postoperative and sepsis-associated delirium and cognitive dysfunction and development of the prophylaxis.Principal Investigator
- Principal Investigator
  
  廣田和美
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Anesthesiology
- Research Institution
  Hirosaki University
Role of orexinergic neurons in sepsisPrincipal Investigator
- Principal Investigator
  
  Hirota Kazuyoshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Anesthesiology
- Research Institution
  Hirosaki University
Searching way of more gentle emergence from general anesthesia-An approach from anesthesiology and sleep to ERAS-
- Principal Investigator
  
  Tetsuya KUSHIKATA
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology
- Research Institution
  Hirosaki University
麻酔後睡眠障害の治療戦略：睡眠ホメオスタシス調節の視点からのアプローチ
- Principal Investigator
  
  吉田仁
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology
- Research Institution
  Hirosaki University
Study on analgesic effects of neuropeptide SPrincipal Investigator
- Principal Investigator
  
  HIROTA Kazuyoshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Hirosaki University
A study on the treatment of post anesthesia and surgical sleep disturbance
- Principal Investigator
  
  KUSHIKATA Tetsuya
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Hirosaki University
Sleep and general anesthesia : maintaining patient safety and improving the QOL during perioperative period
- Principal Investigator
  
  YOSHIDA Hitoshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Hirosaki University
Stud for the mechanism of aging and anesthesia-related sleep disorder and its treatment.Principal Investigator
- Principal Investigator
  
  HIROTA Kazuyoshi
- Project Period (FY)
  2009 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Hirosaki University
Study on a mechanism of emergence from general anesthesia-apply of the ascending arousal system for smooth recovery from general anesthesia
- Principal Investigator
  
  KUSHIKATA Tetsuya
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Hirosaki University
The effects of massage for symptom relief
- Principal Investigator
  
  NOTO Yuka
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Fundamental nursing
- Research Institution
  Hirosaki University
生理活性物質ウロテンシンIIの全身麻酔および睡眠への関与Principal Investigator
- Principal Investigator
  
  廣田和美
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Hirosaki University
The relationship between sleep and anesthesia as a clueto elucidate the mechanism of general anesthesia
- Principal Investigator
  
  YOSHIDA Hitoshi
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Hirosaki University
Brain orexinergic-noradrenergic neurons and mechanism of general anesthesiaPrincipal Investigator
- Principal Investigator
  
  HIROTA Kazuyoshi
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Hirosaki University
A study of post anesthetic and operative sleep disturbance. An approach to the mechanism and treatment on the disturbance.
- Principal Investigator
  
  KUSHIKATA Tetsuya
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Hirosaki University
全身麻酔中の低体温予防の研究-中枢性ノルエピネフリン作動性神経活性は関与するか
- Principal Investigator
  
  MATSUKI Akitomo
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Hirosaki University
Unitary mechanism of general anesthesia using brain noradrenergic neuronal network.Principal Investigator
- Principal Investigator
  
  HIROTA Kazuyoshi
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Hirosaki University
A study on the mechanism of General Anesthesia-inuduced sleep-relation to endogenous sleep related substances
- Principal Investigator
  
  MATSUKI Akitomo
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Hirosaki University
Contribution of L-type Voltage Sensitive Ca^<2+> Channels to Mechanism of General AnesthesiaPrincipal Investigator
- Principal Investigator
  
  HIROTA Kazuyoshi
- Project Period (FY)
  1997 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Hirosaki University
向精神薬ドロペリドールの気管支拡張作用-超細臣ファイバースコープによる直視的判定法-Principal Investigator
- Principal Investigator
  
  廣田和美
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Hirosaki University
喘息発作状態に対するNMDA受容体遮断薬の治療効果Principal Investigator
- Principal Investigator
  
  廣田和美
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Hirosaki University

[Journal Article] Preoperative management and postoperative delirium: The possibility of neuroprehabilitation using virtual reality.2020
- Author(s)
  Hirota K
- Journal Title
  
  J Anesth.
  
  Volume: 34 Pages: 1-4
- DOI
  10.1007/s00540-019-02660-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04319
[Journal Article] Pilot Study of Changes in Presepsin Concentrations Compared With Changes in Procalcitonin and C-Reactive Protein Concentrations After Cardiovascular Surgery2017
- Author(s)
  Saito J, Hashiba E, Mikami A, Kudo T, Niwa H, Hirota K.
- Journal Title
  
  Journal of Cardiothoracic and Vascular Anesthesia
  
  Volume: 17 Pages: 1262-1267
- DOI
  10.1053/j.jvca.2017.02.007
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10529, KAKENHI-PROJECT-15K15561
[Journal Article] Sepsis and the orexin system.2016
- Author(s)
  Hirota K
- Journal Title
  
  Journal of Anesthesia
  
  Volume: 30 Pages: 919-922
- DOI
  10.1007/s00540-016-2246-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15561
[Journal Article] Ketamine and propofol have opposite effects on postanesthetic sleep architecture in rats: relevance to the endogenous sleep-wakefulness substances orexin and melanin-concentrating hormone2016
- Author(s)
  Kushikata T, Sawada M, Niwa H, Kudo T, Kudo M, Tonosaki M, Hirota K.
- Journal Title
  
  Journal of anesthesia
  
  Volume: 30 Pages: 437-43
- DOI
  10.1007/s00540-016-2161-x
- NAID
  40020854416
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26462327
[Journal Article] Ketamine as an NMDA receptor antagonist]2013
- Author(s)
  Kushikata T, Hirota K
- Journal Title
  
  masui
  
  Volume: 62 Pages: 38-43
- NAID
  40019551645
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592242
[Journal Article] Ketamine as an NMDA receptor antagonist2013
- Author(s)
  Kushikata T, Hirota K
- Journal Title
  
  Masui
  
  Volume: 62 Pages: 38-43
- NAID
  40019551645
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592242
[Journal Article] Sleep in anesthesiology e What can we learn about anesthesia from studying sleep?2012
- Author(s)
  Kushikata T, Yoshida Y, Hirota K
- Journal Title
  
  Trends in Anaesthesia and Critical Care
  
  Volume: 2 Pages: 30-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592242
[Journal Article] Sleep in anesthesiology e What can we learn about anesthesia from studying sleep?2012
- Author(s)
  Kushikata T, Yoshida H, Hirota K
- Journal Title
  
  Trends in Anaesthesia and Critical Care
  
  Volume: 2 Pages: 30-35
- DOI
  10.1016/j.tacc.2011.11.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592242
[Journal Article] Neuropeptide microdialysis in free-moving animals2011
- Author(s)
  Kushikata T, Hirota K
- Journal Title
  
  Methods Mol Biol
  
  Volume: 789 Pages: 261-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592242
[Journal Article] The effects of neuropeptide S on general anesthesia in rats2011
- Author(s)
  Kushikata T, Yoshida H, Kudo M, Salvadori S, Calo G, Hirota K
- Journal Title
  
  Anesth Analg
  
  Volume: 112 Pages: 845-849
- DOI
  10.1213/ane.0b013e31820b990d
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390430
[Journal Article] Antinociceptive effects of neurotropin in a rat model of central neuropathic pain : DSP-4 induced noradrenergic lesion.2011
- Author(s)
  Kudo T, Kushikata T, Kudo M, Kudo T, Hirota K
- Journal Title
  
  Neurosci Lett
  
  Volume: 503 Pages: 20-22
- DOI
  10.1016/j.neulet.2011.07.056
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390430
[Journal Article] Use of bispectral index monitoring for a patient with hepatic encephalopathy requiring living donor liver transplantation : a case report2011
- Author(s)
  Okawa H, Ono T, Hashiba E, Tsubo T, Ishihara H, Hirota K
- Journal Title
  
  J Anesth
  
  Volume: 25 Pages: 117-119
- DOI
  10.1007/s00540-010-1055-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390430
[Journal Article] Antinociceptive effects of neurotropin in a rat model of central neuropathic pain: DSP-4 induced noradrenergic lesion2011
- Author(s)
  Kudo T, Kushikata T, Kudo M, Kudo T, Hirota K. .
- Journal Title
  
  Neurosci Lett
  
  Volume: :503 Pages: 20-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592242
[Journal Article] Antinociceptive effects of neurotropin in a rat model of central neuropathic pain : DSP-4 induced noradrenergic lesion2011
- Author(s)
  Kudo T, Kushikata T, Kudo T, Kudo M, Hirota K
- Journal Title
  
  Neurosci Lett
  
  Volume: 503 Pages: 20-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390430
[Journal Article] Antinociceptive effects of neurotropin in a rat model of central neuropathic pain : DSP-4 induced noradrenergic lesion2011
- Author(s)
  Kudo T, Kushikata T, Kudo M, Kudo T, Hirota K
- Journal Title
  
  Neurosci Lett
  
  Volume: 503 Pages: 20-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592242
[Journal Article] Role of coerulean noradrenergic neurones in general anaesthesia in rats2011
- Author(s)
  Kushikata T, Yoshida H, Kudo M, Kudo T, Kudo T, Hirota K
- Journal Title
  
  Br J Anaesth
  
  Volume: 107 Pages: 924-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592242
[Journal Article] Neuropeptide microdialysis in free-moving animals2011
- Author(s)
  Kushikata T, Hirota K
- Journal Title
  
  Methods Mol Biol
  
  Volume: 789 Pages: 261-269
- DOI
  10.1007/978-1-61779-310-3_16
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390430
[Journal Article] Role of cerulean noradrenergic neurones in general anaesthesia in rats2011
- Author(s)
  Kushikata T, Yoshida H, Kudo M, Kudo T, Kudo T, Hirota K
- Journal Title
  
  Br J Anaesth
  
  Volume: 107 Pages: 924-929
- DOI
  10.1093/bja/aer303
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390430
[Journal Article] The Effects of Neuropeptide S on General Anesthesia in Rats2011
- Author(s)
  Kushikata T, Yoshida H, Kudo M, Salvadori S, Calo G, Hirota K
- Journal Title
  
  Anesth Analg
  
  Volume: 112 Pages: 845-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592242
[Journal Article] A central neuropathic pain model by DSP-4 induced lesion of noradrenergic neurons : preliminary report.2010
- Author(s)
  Kudo T, Kushikata T, Kudo M, Kudo T, Hirota K.
- Journal Title
  
  Neurosci Lett
  
  Volume: 481 Pages: 102-104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390430
[Journal Article] Changes in plasma orexin A during propofol-fentanyl anaesthesia in patients undergoing eye surgery2010
- Author(s)
  Kushikata T, Yoshida H, Kudo M, Kudo T, Hirota K
- Journal Title
  
  Br J Anaesth
  
  Volume: 104 Pages: 723-727
- DOI
  10.1093/bja/aeq098
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390430
[Journal Article] The Effects of Neuropeptide S on General Anesthesia in Rats2010
- Author(s)
  Kushikata T, Yoshida H, Kudo M, Salvadori S, Calo G, Hirota K
- Journal Title
  
  Anesth Analg 112巻
  
  Pages: 845-849
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591797
[Journal Article] Plasma orexin A increases at emergence from sevoflurane-fentanyl anesthesia in patients undergoing ophthalmologic surgery.2010
- Author(s)
  Kushikata T, Yoshida H, Kudo M, Kudo T, Hirota K
- Journal Title
  
  Neurosci Lett
  
  Volume: 482 Pages: 212-215
- DOI
  10.1016/j.neulet.2010.07.037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390430
[Journal Article] Nitrous oxide and xenon increase noradrenaline release in the cerebral cortex in vivo and in vitro2010
- Author(s)
  Yoshida H, Kushikata T, Tose R, Kudo M, Kudo T, Hirota K
- Journal Title
  
  Neurosci Lett
  
  Volume: 469 Pages: 199-203
- DOI
  10.1016/j.neulet.2009.11.074
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390430
[Journal Article] The Effects of Neuropeptide S on General Anesthesia in Rats2010
- Author(s)
  Kushikata T, Yoshida H, Kudo M, Salvadori S , Cato G , Hirota K
- Journal Title
  
  Anes thAnalg
  
  Volume: 112 Pages: 845-849
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591797
[Journal Article] Changes in plasma orexin A during propofol-fentanyl anaesthesia in patients unde rgoing eye surgery.2010
- Author(s)
  Kushikata T, Yoshida H, Kudo M, Kudo T, Hirota K.
- Journal Title
  
  Br J Anaesth
  
  Volume: 104 Pages: 723-727
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390430
[Journal Article] A central neuropathic pain model by DSP-4 induced lesion of noradrenergic neurons : preliminary report2010
- Author(s)
  Kudo T, Kushikata T, Kudo M, Kudo T, Hirota K
- Journal Title
  
  Neurosci Lett
  
  Volume: 481 Pages: 102-104
- DOI
  10.1016/j.neulet.2010.06.061
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390430
[Journal Article] Plasma orexin A increases at emergence trom sevotlurane-tentanyl anesthesia in patients undergoing ophthalmologic surgery.2010
- Author(s)
  Kushikata T, Yoshida H, Kudo M, Kudo T_ Hirota K.
- Journal Title
  
  Neurosci Lett
  
  Volume: 482 Pages: 212-215
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390430
[Journal Article] The effects of benzodiazepines on urotensin II-stimulated norepinephrine release from rat cerebrocortical slices2009
- Author(s)
  Kawaguchi Y, Ono T, Kudo M, Kushikata T, Hashiba E, Yoshida H, Kudo T, Furukawa K, Douglas SA, Hirota K
- Journal Title
  
  Anesth Analg
  
  Volume: 108 Pages: 1177-1181
- DOI
  10.1213/ane.0b013e3181981faa
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390430
[Journal Article] Interaction between orexinergic neurons and NMDA receptors in the control of locus coeruleus-cerebrocortical noradrenergic activity of the rat2009
- Author(s)
  Tose R, Kushikata T, Yoshida H, Kudo M, Furukawa K, Ueno S, Hirota K
- Journal Title
  
  Brain Res 1250巻
  
  Pages: 81-87
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591797
[Journal Article] Orexin A decreases ketamine-induced anesthesia time in the rat : the relevance to brain noradrenergic neuronal activity.2009
- Author(s)
  Tose R, Kushikata T, Yoshida H, Kudo M, Furukawa K, Ueno S, Hirota K
- Journal Title
  
  Anesth Analg. 108
  
  Pages: 491-495
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591797
[Journal Article] The effects of benzodiazepines on urotensin II-stimulated norepinephrine release from rat cerebrocortical slices.2009
- Author(s)
  Kawaguchi Y, Ono T, Kudo M, Kushikata T, Hashiba E, Yoshida H, Kudo T, Furukawa K, Douglas SA, Hirota K.
- Journal Title
  
  Anesthesia and Analgesia 108
  
  Pages: 1177-1181
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659395
[Journal Article] Orexin A decreases ketamine-induced anesthesia time in the rat : the relevance to brain noradrenergic neuronal activity2009
- Author(s)
  Tose R, Kushikata T, Yoshida H, Kudo M, Furukawa K, Ueno S, Hirota K
- Journal Title
  
  Anesth Analg 108巻
  
  Pages: 491-495
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591797
[Journal Article] Interaction between orexinergic neurons and NMDA receptors in the control oflocus coeruleus-cerebrocortical noradrenergic activity of the rat.2009
- Author(s)
  Tose R, Kushikata T, Yoshida H, Kudo M, Furukawa K, Ueno S, Hirota K
- Journal Title
  
  Brain Res. 1250
  
  Pages: 81-87
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591797
[Journal Article] Role of the orexinergic system in acute haemorrhage in the rat2008
- Author(s)
  Hirota K, Kushikata T, Yoshida H, Kudo M, Kudo T.
- Journal Title
  
  Neurosci Lett 432
  
  Pages: 162-166
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390423
[Journal Article] Noradrenergic neuronal network and mechanism of general anesthesia2008
- Author(s)
  Hirota K, Kushikata T.
- Journal Title
  
  Igaku No Ayumi (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390423
[Journal Article] Urotensin II evokes neurotransmitter release from rat cerebrocortical slices2008
- Author(s)
  Ono T, Kawaguchi Y, Kudo M, Kushikata T, Hashiba E, Yoshida H, Kudo T, Furukawa K, Douglas SA, Guerrini R, Calo' G, Hirota K
- Journal Title
  
  Neurosci Lett 440(3)
  
  Pages: 275-279
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659395
[Journal Article] Urotensin II evokes neurotransmitter release from rat cerebrocortical slices2008
- Author(s)
  Ono T, Kawaguchi Y, Kudo M, Kushikata T, Hashiba E,Yoshida H, Kudo T, Furukawa K, Douglas SA, Guerrini R, Calo' G, Hirota K
- Journal Title
  
  Neurosci Lett 440巻
  
  Pages: 275-279
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591797
[Journal Article] Urotensin II evokes neurotransmitter release from rat cerebrocortical slices2008
- Author(s)
  Ono T, Kawaguchi Y, Kudo M, Kushikata T, Hashiba E, Yoshida H, Kudo T, Furukawa K, Douglas SA, Guerrini R, Calo G, Hirota K
- Journal Title
  
  Neurosci Lett 440(3)
  
  Pages: 275-279
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591797
[Journal Article] Role of the orexinergic system in acute haemorrhage in the rat.2008
- Author(s)
  Hirota K, Kushikata T, Yoshida H, Kudo M, Kudo T.
- Journal Title
  
  Neurosci Lett 432
  
  Pages: 162-166
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390423
[Journal Article] ノルアドレナリン神経ネットワークと全身麻酔機序.2008
- Author(s)
  廣田和美、櫛方哲也.
- Journal Title
  
  医学の歩み (In press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390423
[Journal Article] Anesthesia and sleep-Part 1. Recent findings of sleep2007
- Author(s)
  Kushikata T, Yoshida H, Yasuda T, Tose Ryuji, Hirota Kazuyoshi, and Matsuki Akitomo
- Journal Title
  
  Masui 56
  
  Pages: 1047-1052
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591608
[Journal Article] 麻酔と睡眠-第2部:麻酔と睡眠の関連について-2007
- Author(s)
  櫛方哲也、吉田仁、安田忠伸、遠瀬龍二、廣田和美、松木明知
- Journal Title
  
  麻酔 56
  
  Pages: 1148-54
- NAID
  40015650046
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17591608
[Journal Article] オレキシンとノルエピネフリン覚醒システム.2007
- Author(s)
  廣田和美
- Journal Title
  
  麻酔 56
  
  Pages: 9-18
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390423
[Journal Article] Effects of back massage on psychological status and salivary biomarkers2007
- Author(s)
  Yuka Noto, Mihoko Kudo, Tetsumi Sato, Masako Ebina, and Kazuyoshi Hirota
- Journal Title
  
  弘前医学 59巻
  
  Pages: 188-192
- NAID
  110006602926
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592424
[Journal Article] Anesthesia and sleep-Part 2. On relationship between Sleep and Anesthesia2007
- Author(s)
  Kushikata T, Yoshida H, Yasuda T, Tose Ryuji, Hirota Kazuyoshi, and Matsuki Akitomo
- Journal Title
  
  Masui 56
  
  Pages: 1148-1154
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591608
[Journal Article] Orexinergic neurons and noradrenergic awakening system in general anesthesia2007
- Author(s)
  Hirota K.
- Journal Title
  
  Masui 56
  
  Pages: 9-18
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390423
[Journal Article] Effects of back massage on psychological status and salivary biomarkers2007
- Author(s)
  Yuka Noto, Mihoko Kudo, Tetsumi Sato, Masako Ebina, and Kazuyoshi Hirota
- Journal Title
  
  弘前医学 59
  
  Pages: 188-192
- NAID
  110006602926
- Data Source
  KAKENHI-PROJECT-19592424
[Journal Article] 麻酔と睡眠-第1部 : 睡眠に関する最近の知見-2007
- Author(s)
  櫛方哲也、吉田仁、廣田和美(他3名)
- Journal Title
  
  麻酔 56
  
  Pages: 1047-1052
- NAID
  40015624012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591684
[Journal Article] 麻酔と睡眠-第2部:麻酔と睡眠の関連について-2007
- Author(s)
  櫛方哲也、吉田仁、安田忠伸、遠瀬龍二、廣田和美、松木明知
- Journal Title
  
  麻酔 56
  
  Pages: 1148-54
- NAID
  40015650046
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17591608
[Journal Article] The effects of benzodiazepines on orexinergic systems in rat cerebrocortical slices.2007
- Author(s)
  He Y, Kudo M, Kudo T, Kushikata T, Li E, Hirota K.
- Journal Title
  
  Anesth Analg 104
  
  Pages: 338-340
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390423
[Journal Article] 麻酔と睡眠-第1部:睡眠に関する最近の知見2007
- Author(s)
  櫛方哲也、吉田仁、安田忠伸、遠瀬龍二、廣田和美、松木明知
- Journal Title
  
  麻酔 56
  
  Pages: 1047-52
- NAID
  40015624012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17591608
[Journal Article] The effects of benzodiazepines on orexinergic systems in rat cerebrocortical slices2007
- Author(s)
  He Y, Kudo M, Kudo T, Kushikata T, Li E, Hirota K.
- Journal Title
  
  Anesth Analg 104
  
  Pages: 338-340
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390423
[Journal Article] オレキシンとノルエピネフリン覚醒システム.2007
- Author(s)
  廣田和美.
- Journal Title
  
  麻酔 56
  
  Pages: 9-18
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390423
[Journal Article] 麻酔と睡眠-第1部:睡眠に関する最近の知見2007
- Author(s)
  櫛方哲也、吉田仁、安田忠伸、遠瀬龍二、廣田和美、松木明知
- Journal Title
  
  麻酔 56
  
  Pages: 1047-52
- NAID
  40015624012
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17591608
[Journal Article] 麻酔と睡眠-第2部 : 麻酔と睡眠の関連について-2007
- Author(s)
  櫛方哲也、吉田仁、廣田和美(他3名)
- Journal Title
  
  麻酔 56
  
  Pages: 1148-1154
- NAID
  40015650046
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591684
[Journal Article] Special cases: ketamine, nitrous oxide and xenon2006
- Author(s)
  Hirota K.
- Journal Title
  
  Best Pract Res Clin Anaesthesiol 202
  
  Pages: 69-79
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390423
[Journal Article] Special cases: ketamine, nitrous oxide and xenon.2006
- Author(s)
  Hirota K.
- Journal Title
  
  Best Pract Res Clin Anaesthesiol 202
  
  Pages: 69-79
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390423
[Journal Article] Special cases : ketamine, nitrous oxide and xenon.2006
- Author(s)
  Hirota K, Kudo M, Tose R, et al.
- Journal Title
  
  Best Pract Res Clin Anaesthesiol 20
  
  Pages: 69-79
- Data Source
  KAKENHI-PROJECT-17390423
[Journal Article] Isoflurane increases norepinephrine release in the rat preoptic area and the posterior hypothalamus in vivo and in vitro : Relevance to thermoregulation during anesthesia.2005
- Author(s)
  Kushikata T, Hirota K, Kotani N, Yoshida H, Kudo M, Matsuki A.
- Journal Title
  
  Neuroscience 131
  
  Pages: 79-86
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370480
[Journal Article] Lack of interaction between orexinergic and alpha2-adrenergic neuronal systems in rat cerebrocortical slices.2005
- Author(s)
  Hirota K, Kudo M, Tose R, Yoshida H, Kudo T, Kushikata T.
- Journal Title
  
  Neurosci Lett 387
  
  Pages: 49-52
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370480
[Journal Article] Lack of interaction between orexinergic and alpha2-adrenergic neuronal systems in rat cerebrocortical slices2005
- Author(s)
  Hirota K, Kudo M, Tose R, Yoshida H, Kudo T, Kushikata T.
- Journal Title
  
  Neurosci Lett 387
  
  Pages: 49-52
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390423
[Journal Article] Lack of interaction between orexinergic and alpha2-adrenergic neuronal systems in rat cerebrocortical slices.2005
- Author(s)
  Hirota K, Kudo M, Tose R, Yoshida H, Kudo T, Kushikata T.
- Journal Title
  
  Neurosci Lett 387
  
  Pages: 49-52
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390423
[Journal Article] Isoflurane increases norepinephrine release in the rat preoptic area and the posterior hypothalamus in vivo and in vitro: Relevance to thermoregulation during anesthesia2005
- Author(s)
  Kushikata T, Hirota K, Kotani N, Yoshida H, Kudo M, Matsuki A.
- Journal Title
  
  Neuroscience 131
  
  Pages: 79-86
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390423
[Journal Article] Isoflurane increases norepinephrine release in the rat preoptic area and the posterior hypothalamus in vivo and in vitro: Relevance to thermoregulation during anesthesia.2005
- Author(s)
  Kushikata T, Hirota K, Kotani N, Yoshida H, Kudo M, Matsuki A.
- Journal Title
  
  Neuroscience 131
  
  Pages: 79-86
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390423
[Journal Article] Lack of interaction between orexinergic and α_2-adrenergic neuronal systems in rat cerebrocortical slices.2005
- Author(s)
  Hirota K, Kudo M, Tose R, et al.
- Journal Title
  
  Neuroscience Letters 387
  
  Pages: 49-52
- Data Source
  KAKENHI-PROJECT-17390423
[Journal Article] Supraclinical concentrations of dexmedetomidine evoke norepinephrine release from rat cerebrocortical slices possible involvement of the orexin-1 receptor.2004
- Author(s)
  Hirota K, Nomura H, Kudo M, Mori N, Kudo T, Kushikata T.
- Journal Title
  
  Neurosci Lett 372
  
  Pages: 142-5
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370480
[Journal Article] Supraclinical concentrations of dexmedetomidine evoke norepinephrine release from rat cerebrocortical slices possible involvement of the orexin-1 receptor.2004
- Author(s)
  Hirota K, Nomura H, Kudo M, et al.
- Journal Title
  
  Neuroscience Letters 372
  
  Pages: 142-145
- Data Source
  KAKENHI-PROJECT-14370480
[Journal Article] Role of noradrenergic and orexinergic neurons in general anaesthesia.2003
- Author(s)
  Hirota K, Kushikata T, Kudo M.
- Journal Title
  
  Current Neuropharmacology 1
  
  Pages: 333-40
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370480
[Journal Article] Effects of central hypocretin-1 administration on hemodynamic responses in young-adult and middle aged rats.2003
- Author(s)
  Hirota K, Kushikata T, Kudo M, Kudo T, Smart D, Matsuki A.
- Journal Title
  
  Brain Res 981
  
  Pages: 143-50
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370480
[Journal Article] Lade of an interaction between orexinergic and opioid/nociceptin systems in rat cerebrocortical slices.2003
- Author(s)
  Hirota K, Kushikata T, Kudo M.Kudo T, Lambert DG, Smart D, Matsuki A.
- Journal Title
  
  Neurosci Lett 340
  
  Pages: 173-176
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370480
[Journal Article] Orexinergic neuron and barbiturate anesthesia.2003
- Author(s)
  Kushikata T, Hirota K, Yoshida H, Kudo M, Lambert DG, Smart D, Jerman JC, Matsuki A.
- Journal Title
  
  Neuroscience 121
  
  Pages: 855-63
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370480
[Journal Article] Lack of an interaction between orexinergic and opioid/nociceptin systems in rat cerebrocortical slices.2003
- Author(s)
  Hirota K, Kushikata T, Kudo M, Kudo T, Lambert DG, Smart D, Matsuki A.
- Journal Title
  
  Neurosci Lett 340
  
  Pages: 173-6
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370480
[Journal Article] Inhibitory effects of intravenous anesthetic agents on K^+-evoked glutamate release from rat cerebrocortical slices. Involvement of voltage sensitive Ca^<2+> channels and GABA_A receptors.2002
- Author(s)
  Kitayama M, Hirota K, Kudo M, Kudo T, Ishihara H, Matsuki A.
- Journal Title
  
  Naunyn Schmiedbergs Arch Pharmacol 366
  
  Pages: 246-53
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370480
[Journal Article] Alpha-2 adrenoceptor activity affects propofol-induced sleeping time.2002
- Author(s)
  Kushikata T, Hirota K, Yoshida H, Kubota T, Ishihara H, Matsuki A.
- Journal Title
  
  Anesth Analg 94
  
  Pages: 1201-6
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370480
[Presentation] Involvement of meurodegenerative and neuroinflammatory processes in the pathogenesis of postoperative delirium in elderly mice.2019
- Author(s)
  Nikaido Y, Tatara Y, Kushikata T, Hirota K.
- Organizer
  Hirosaki Medical Science Forum
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04319
[Presentation] Investigation of the effect of perioperative inflammation on electroencephalogram2019
- Author(s)
  Hirotaka Kinoshita, Tetsuya Kushikata, Daiki Takekawa, Kazuyoshi Hirota
- Organizer
  The 6th Congress of Asian Society for Neuroanesthesia and Critical Care
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04319
[Presentation] 敗血症患者における血中オレキシン濃度の変化の検討.2017
- Author(s)
  赤石真啓、橋場英二、天内絵理香、太田大地、櫛方哲也、廣田和美.
- Organizer
  日本麻酔科学会第64回学術集会
- Data Source
  KAKENHI-PROJECT-15K15561
[Presentation] Orexinergic tone affects survival in sepsis in rats.2017
- Author(s)
  Hirota K, Takekawa D, Kushikata T, Kudo M.
- Organizer
  BJA Research Forum Winter Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15561
[Presentation] ケタミンの麻酔・鎮痛機序におけるオレキシン作動性神経の関与は異なる。-オレキシン遺伝子改変ラット（OX/ATA3 TG rat）を用いた研究-2016
- Author(s)
  外崎　充、櫛方哲也、丹羽英智、齋藤淳一、工藤隆司、廣田和美
- Organizer
  日本麻酔科学会第63回学術集会
- Place of Presentation
  福岡国際会議場（福岡県、福岡市）
- Year and Date
  2016-05-26
- Data Source
  KAKENHI-PROJECT-26462327
[Presentation] Ketamine disturbs post anesthesia sleep in aged rat–relevance to brain Orexin contents?2015
- Author(s)
  Tetsuya KUSHIKATA, MD, Ph. D, Izumi Miki, B Sc, Mitsuru Tonosaki , MD, Hidetomo Niwa, MD, Ph. D, Jyunichi Saito, MD, Ph. D, Kazuyoshi HIROTA, MD, Ph. D, FRCA
- Organizer
  The 9th lnternationaI Conference on Mechanisms of Anaesthesia
- Place of Presentation
  ボン市、ドイツ
- Year and Date
  2015-06-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462327
[Presentation] ニューロペプチドＳの鎮痛作用は下行性抑制系が関与する2014
- Author(s)
  地主継、櫛方哲也、廣田和美、他
- Organizer
  日本麻酔科学会第61回学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-05-01
- Data Source
  KAKENHI-PROJECT-24659690
[Presentation] 内因性神経ペプチドNeuropeptide Sは睡眠リズム形成に関与する-ラットにおけるアンタゴニストを用いた研究-2014
- Author(s)
  大石将文、櫛方哲也、丹羽英智、矢越ちひろ、小笠原千尋、廣田和美
- Organizer
  日本麻酔科学会第61回学術集会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-23592242
[Presentation] オレキシンによる交感神経制御(Tgラットによる循環系評価)2013
- Author(s)
  村上学、櫛方哲也、丹羽英智、大場貴喜、尾野恭一、廣田和美
- Organizer
  第45回東北生理談話会
- Place of Presentation
  仙台
- Year and Date
  2013-10-05
- Data Source
  KAKENHI-PROJECT-23592242
[Presentation] 全身麻酔薬による鎮静、鎮痛機序-ノルアドレナリン作動性神経系から見た提言-2013
- Author(s)
  櫛方哲也、廣田和美
- Organizer
  第60回日本麻酔科学会
- Place of Presentation
  札幌
- Year and Date
  2013-05-24
- Data Source
  KAKENHI-PROJECT-23592242
[Presentation] プロポフォ-ル麻酔後のレム睡眠減少にMelanin-Concentrating Hormone(MCH)が関与する2013
- Author(s)
  澤田匡宏、櫛方哲也、地主継、工藤隆司、外崎充、廣田和美
- Organizer
  第60回日本麻酔科学会
- Place of Presentation
  札幌
- Year and Date
  2013-05-23
- Data Source
  KAKENHI-PROJECT-23592242
[Presentation] 麻酔と睡眠-麻酔からの覚醒について-2012
- Author(s)
  櫛方哲也、廣田和美
- Organizer
  第37回日本睡眠学会
- Place of Presentation
  横浜
- Year and Date
  2012-06-30
- Data Source
  KAKENHI-PROJECT-23592242
[Presentation] シンポジウムS37 麻酔と睡眠-麻酔からの覚醒について-2012
- Author(s)
  櫛方哲也、廣田和美
- Organizer
  日本睡眠学会第37回定期学術集会
- Place of Presentation
  横浜市
- Invited
- Data Source
  KAKENHI-PROJECT-23592242
[Presentation] 麻酔と睡眠-麻酔からの覚醒について-2012
- Author(s)
  櫛方哲也,廣田和美
- Organizer
  第37回日本睡眠学会
- Place of Presentation
  横浜
- Year and Date
  2012-06-30
- Data Source
  KAKENHI-PROJECT-21390430
[Presentation] 麻酔と睡眠　-麻酔からの覚醒について-2012
- Author(s)
  櫛方哲也、廣田和美
- Organizer
  日本睡眠学会第37回定期学術集会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-21390430
[Presentation] 脳内ノルアドレナリン神経網と麻酔および意識との関係2011
- Author(s)
  廣田和美
- Organizer
  第20回日本意識障害学会
- Place of Presentation
  弘前
- Year and Date
  2011-09-02
- Data Source
  KAKENHI-PROJECT-21390430
[Presentation] Neuropeptide S attenuates increase in REM sleep following ketamine anesthesia2011
- Author(s)
  Kushikata T, Calo' G, Moriya K, Oishi M, Yakoshi C, Hirota K
- Organizer
  8th World Congress of Neuroscience by International Brain Organization
- Place of Presentation
  フローレンス,イタリア共和国
- Data Source
  KAKENHI-PROJECT-21390430
[Presentation] Neuropeptide S attenuates increase in REM sleep following ketamine anesthesia2011
- Author(s)
  Kushikata T, Calo'G, Moriya K, Oishi M, Yakoshi C, Hirota K
- Organizer
  8th World Congress of Neuroscience by International Brain Organization
- Place of Presentation
  フローレンス市、イタリア共和国
- Data Source
  KAKENHI-PROJECT-21390430
[Presentation] Ketamine modified Melanin-Concentrating Hormone in rat brain2011
- Author(s)
  Kushikata T, Sawada M, Oishi M, Moriya K, Yoshida H, Hirota K
- Organizer
  Worldsleep 2011
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21390430
[Presentation] Ketamine modified Melanin-Concentrating Hormone in rat brain2011
- Author(s)
  Kushikata T, Sawada M, Oishi M, Moriya K, Yoshida H, Hirota K
- Organizer
  Worldsleep2011
- Place of Presentation
  京都市、日本
- Data Source
  KAKENHI-PROJECT-21390430
[Presentation] Orexin reduced ketamine anesthesia-induced sleep disturbance2010
- Author(s)
  Kushikata T, Hirota K
- Organizer
  Neuro-Talk-2010
- Place of Presentation
  シンガポール共和国
- Data Source
  KAKENHI-PROJECT-21390430
[Presentation] Ketamine affects brain orexin A contents in rats2010
- Author(s)
  Oishi M, Moriya K, Saito C, Kudo M, Kushikata T, Hirota K
- Organizer
  12th Meeting of Hirosaki International Forum of Medical Science
- Place of Presentation
  弘前
- Year and Date
  2010-10-30
- Data Source
  KAKENHI-PROJECT-21390430
[Presentation] Orexin reduced ketamine anesthesia-induced sleep disturbance.2010
- Author(s)
  Kushikata T, Hirota K.
- Organizer
  Neuro-Talk 2010
- Place of Presentation
  Singapore
- Data Source
  KAKENHI-PROJECT-21390430
[Presentation] I Ketamine affects brain orexin A contents in rats.2010
- Author(s)
  Oishi M, Moriya K, Saito C, Kudo M, Kushikata T, Hirota K.
- Organizer
  12<th> Meeting of Hirosaki International Forum of Medical Science
- Place of Presentation
  Hirosaki
- Year and Date
  2010-10-30
- Data Source
  KAKENHI-PROJECT-21390430
[Presentation] Effects of ketamine anaesthesia on brain orexin A contents in rats2010
- Author(s)
  Hirota K
- Organizer
  Winter Scientific Meeting of the Anaesthetic Research Society
- Place of Presentation
  ロンドン,連合王国
- Year and Date
  2010-11-12
- Data Source
  KAKENHI-PROJECT-21390430
[Presentation] 青斑核由来の脳内ノルアドレナリン作動性神経活性はチオペンタール麻酔機序に関与する2010
- Author(s)
  櫛方哲也、吉田仁、丹羽英智、工藤隆司、和田盛人、廣田和美
- Organizer
  第57回日本麻酔科学会
- Place of Presentation
  福岡
- Year and Date
  2010-06-04
- Data Source
  KAKENHI-PROJECT-21390430
[Presentation] Orexin decreased ketamine anesthesia-induced sleep disturbance2010
- Author(s)
  Kushikata T, Oishi M, Moriya K, Saito C, Yoshida H, Hirota K
- Organizer
  12th Meeting of Hirosaki International Forum of Medical Science
- Place of Presentation
  弘前
- Year and Date
  2010-10-30
- Data Source
  KAKENHI-PROJECT-21390430
[Presentation] Preoperative cerebral infarction causesbispectral index asymmetry2009
- Author(s)
  吉田仁、櫛方哲也、廣田和美(他3名)
- Organizer
  International Anesthesia Research Society 2009 Annual Meeting
- Place of Presentation
  アメリカ合衆国サンディエゴ
- Year and Date
  2009-03-16
- Data Source
  KAKENHI-PROJECT-18591684
[Presentation] 進行がん患者のリンパ浮腫ケアの効果2008
- Author(s)
  野戸結花、浅利三和子、佐藤哲観、蝦名正子、丹羽英智、工藤美穂子、廣田和美、阿部由直
- Organizer
  第13回日本緩和医療学会学術大会
- Place of Presentation
  静岡
- Year and Date
  2008-07-05
- Data Source
  KAKENHI-PROJECT-19592424
[Presentation] Orexin decreased ketamine anesthesia time in rat. -Relevance to brain noradrenergic neuronal activity2006
- Author(s)
  Tose R, Kushikata T, Yoshida H, Yasuda, Kudo M, Hirota K.
- Organizer
  80th Clinical and Scientific Congress of International A nesthesia Research Society,
- Place of Presentation
  San Francisco
- Year and Date
  2006-03-26
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390423
[Presentation] Orexin decreased ketamine anesthesia time in rat. -Relevance to brain noradrenergic neuronal activity2006
- Author(s)
  Tose R, Kushikata T, Yoshida H, Yasuda, Kudo M, Hirota K.
- Organizer
  80th Clinical and Scientific Congress of International Anesthesia Research Society
- Place of Presentation
  San Francisco
- Year and Date
  2006-03-26
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390423
[Presentation] 亜酸化窒素の大脳皮質ノルアドレナリン放出に与える影響.2006
- Author(s)
  吉田仁、櫛方哲也、遠瀬龍二、工藤美穂子、石原弘規、廣田和美
- Organizer
  第53回日本麻酔科学会総会
- Place of Presentation
  神戸
- Year and Date
  2006-06-01
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390423
[Presentation] Plasma orexin A increases by hemorrhagic shock2006
- Author(s)
  Kushikata T, Hirota K, Yoshida H, Tose R, Kudo M.
- Organizer
  The 53th Annual Meeting of Japan Society of. Anesthesiolohists
- Place of Presentation
  Kobe
- Year and Date
  2006-06-01
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390423
[Presentation] オレキシンがケタミンン麻酔に与える影響-ノルアドレナリン作動性神経活性との関連において-.2006
- Author(s)
  遠瀬龍二、櫛方哲也、吉田仁、安田忠伸、工藤美穂子、工藤剛、廣田和美
- Organizer
  第53回日本麻酔科学会総会
- Place of Presentation
  神戸
- Year and Date
  2006-06-01
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390423
[Presentation] Effects of nitrous oxide on noradrenaline release from the cerebral cortex in rats2006
- Author(s)
  Yoshida H, Kushikata T, Tose R, Kudo M, Ishihara H, Hirota K.
- Organizer
  The 53th Annual Meeting of Japan Society of Anesthesiolohists
- Place of Presentation
  Kobe
- Year and Date
  2006-06-01
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390423
[Presentation] Effects of orexin on ketamine anesthesia. The relation with activity of noradrenergic neurons2006
- Author(s)
  Tose R, Kushikata T, Yoshida H, Yasuda T, Kudo M, Kudo T, Hirota K.
- Organizer
  The 53th Annual Meeting of Japan Society of Anesthesiolohists
- Place of Presentation
  Kobe
- Year and Date
  2006-06-01
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390423
[Presentation] 出血性ショックは血漿中のオレキシンA(OXA)濃度を増加させる.-オレキシン受容体拮抗薬SB-334867を用いた研究-.2006
- Author(s)
  櫛方哲也、廣田和美、吉田仁、遠瀬龍二、工藤美穂子
- Organizer
  第53回日本麻酔科学会総会
- Place of Presentation
  神戸
- Year and Date
  2006-06-01
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390423
[Presentation] The effects of benzodiazepines on orexinergic systems in rat cerebrocortical slices2005
- Author(s)
  Kushikata T, Kudo M, Kudo T, Hirota K.
- Organizer
  The 12^<th> Japan Society for Intravenous Anesthesia And Infusion Technology
- Place of Presentation
  Chiba
- Year and Date
  2005-12-10
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390423
[Presentation] オレキシン作動性神経とアルファ2受容体の相互作用の欠如について.2005
- Author(s)
  櫛方哲也、遠瀬龍二、吉田仁、廣田和美.
- Organizer
  第52回日本麻酔科学会総会
- Place of Presentation
  神戸
- Year and Date
  2005-06-01
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390423
[Presentation] Lack of interaction between orexinergic and alpha2-adrenergic neuronal systems in rat cerebrocortical slices2005
- Author(s)
  Kushikata T, Tose R, Yoshida H, Hirota K.
- Organizer
  The 52th Annual Meeting of Japan Society of Anesthesiolohists
- Place of Presentation
  Kobe
- Year and Date
  2005-06-01
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390423
[Presentation] オレキシンによるラット大脳皮質スライスからの選択的ノルエピネフリン放出に対するベンゾジアゼピンの抑制効果.2005
- Author(s)
  櫛方哲也、工藤美穂子、工藤剛、廣田和美
- Organizer
  第12回日本静脈麻酔・Infusion Technology研究会
- Place of Presentation
  千葉
- Year and Date
  2005-12-10
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390423
[Presentation] オレキシン作動性神経はケタミンの鎮痛作用に関与する-Transgenic Rat（OX/ATA3 TG rat）を用いた研究-
- Author(s)
  外崎充、櫛方哲也、佐々木剛範、丹羽英智、廣田和美、工藤隆司
- Organizer
  公益社団法人日本麻酔科学会第 61回学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-05-15 – 2014-05-17
- Data Source
  KAKENHI-PROJECT-26462327

1. KUSHIKATA Tetsuya (80250603)

# of Collaborated Projects: 20 results

# of Collaborated Products: 99 results
2. KUDO Mihoko (30003411)

# of Collaborated Projects: 10 results

# of Collaborated Products: 58 results
3. YOSHIDA Hitoshi (00374843)

# of Collaborated Projects: 10 results

# of Collaborated Products: 51 results
4. 二階堂義和 (50613478)

# of Collaborated Projects: 6 results

# of Collaborated Products: 1 results
5. KUDO Tsuyoshi (70003407)

# of Collaborated Projects: 3 results

# of Collaborated Products: 30 results
6. KUDO Takashi (40613352)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. 橋場英二 (10374844)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
8. 斎藤淳一 (90647413)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
9. OKAWA Hirobumi (40322953)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
10. MATSUKI Akitomo (20003543)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. 丹羽英智 (20374845)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
12. KUBOTA Takeshi

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. NOTO Yuka (80250629)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
14. SATO Tetsumi (30281934)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
15. KITAJIMA Maiko (70455731)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 小谷直樹 (30205405)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 上野伸哉 (00312158)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 村上学 (80302090)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 畠山真吾 (10400136)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 大山力 (80282135)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 北山眞任 (80374841)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 中井希紫子 (60645266)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 佐々木賀広 (70178672)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 竹川大貴 (80834803)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 安沢則之

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Hirota Kazuyoshi 廣田 和美

HIROTA Kazuyoshi 廣田 和美

廣田 和美 ヒロタ カズミ

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Clinical study for preoperative prediction of depression in older adult patients by deep learning and basic study for clarifying mechanism of depression and developing its prophylaxis.Principal Investigator

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バーチャルリアリティを用いたプレハビリテーションプログラムによる術後譫妄予防Principal Investigator

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Investigation of mechanism of pathogenesis of postoperative and sepsis-associated delirium and cognitive dysfunction and development of the prophylaxis.Principal Investigator

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Role of orexinergic neurons in sepsisPrincipal Investigator

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Study on analgesic effects of neuropeptide SPrincipal Investigator

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Stud for the mechanism of aging and anesthesia-related sleep disorder and its treatment.Principal Investigator

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Hirota Kazuyoshi 廣田和美

HIROTA Kazuyoshi 廣田和美

廣田和美ヒロタカズミ