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Hirota Kazuyoshi  廣田 和美

ORCIDConnect your ORCID iD *help
… Alternative Names

HIROTA Kazuyoshi  廣田 和美

廣田 和美  ヒロタ カズミ

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Researcher Number 20238413
Other IDs
External Links
Affiliation (Current) 2022: 弘前大学, 医学研究科, 教授
Affiliation (based on the past Project Information) *help 2016 – 2021: 弘前大学, 医学研究科, 教授
2011 – 2015: 弘前大学, 医学(系)研究科(研究院), 教授
2013: 弘前大学, 医学研究科, 教授
2007 – 2011: Hirosaki University, Hirosaki University, Graduate School of Medicine, Professor
2004 – 2006: Hirosaki University, School of Medicine, Professor, 医学部, 教授 … More
2002 – 2003: Hirosaki University, University Hospital Lecturer, 医学部附属病院, 講師
2001 – 2002: 弘前大学, 医学部・附属病院, 講師
1996 – 2000: 弘前大学, 医学部・附属病院, 助手
1994: 弘前大学, 医学部・附属病院, 助手 Less
Review Section/Research Field
Principal Investigator
Anesthesiology/Resuscitation studies / Anesthesiology/Resuscitation studies / Anesthesiology / Basic Section 55050:Anesthesiology-related / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
Except Principal Investigator
Anesthesiology/Resuscitation studies / Basic Section 55050:Anesthesiology-related / Anesthesiology / Fundamental nursing / Anesthesiology/Resuscitation studies
Keywords
Principal Investigator
ラット / 大脳皮質 / ノルエピネフリン / ノルアドレナリン / オレキシン / 気管支鏡 / 神経伝達物質 / 麻酔 / 神経生理活性物質 / GABA_A受容体 … More / マイクロダイアリーシス / 静脈麻酔薬 / ケタミン / 大脳皮質スライス / orexin / rat / 敗血症 / 高齢者 / NMDA受容体遮断薬 / ケコミン / マグネシウム / 喘息 / 炎症 / 気管支平滑筋 / 気管支拡張 / ドロペリドール / ヒスタミン / セロトニン / NIH Image / 気道モニタリング / ウロテンシンII / 細胞内Ca / UT受容体 / HEK293-UII細胞 / UFP-803 / 睡眠障害 / 加齢 / 全身麻酔 / 鎮静 / オピオイド / ニューロペプチドS / 鎮痛 / 青斑核 / ニューロペプタイドS / 麻酔薬 / グルタメート / ドーパミン / 電位依存性カルシウムチャンネル / アセチルコリン受容体 / GABA受容体 / 線条体 / チオペンタール / ペントバルビタール / フェノバルビタール / バルビツール酸 / バルビチュレート / カルシウムチャンネルブロッカー / プロポフォール / General anesthetic agents / Noradrenaline / Dopamine / Glutamate / Voltage sensitive Ca^<2+> channel / GABA_A receptor / Rats / Microdialysis / OX1受容体 / α_2-アドレナリン受容体 / MK801 / NMDA受容体 / バルビタール / 細胞内カルシウム濃度 / anesthesia / norepinephrine / OX_1 receptor / Cerebral cortex / 電撃痙攣療法 / α受容体作リガンド / ベンゾジアゼピン / 神経組織 / 吸入麻酔薬 / noradrenaline / microdialysis / cerebrocortical slice / メラニン凝集ホルモン / 譫妄 / 認知機能 / 手術侵襲 / うつ / Deep learning / バーチャルリアリティ / プレハビリテーション / 術後譫妄 / バーチャルリアリティー … More
Except Principal Investigator
睡眠 / 全身麻酔 / 脳波 / 内因性睡眠物質 / 脳・神経 / 麻酔 / 覚醒 / 睡眠障害 / オレキシン / ノルアドレナリン / 全身麻酔薬 / Sleep / α_1レセプター / 視索前野 / 低体温 / マッサージ / 症状緩和 / リンパ浮腫 / 唾液中biomarkers / 唾液中バイオマーカー / STAI-s / 唾液中α-Amylase濃度 / 唾液中CgA濃度 / 唾液中sIgA濃度 / STAI / 麻酔学 / 麻酔の質 / 麻酔科学 / 内因性NPS / 麻酔・手術後の睡眠、認知障害 / ノンレム睡眠 / レム睡眠 / 内因性覚醒物質 / MCH / 鎮痛 / 麻酔時間 / ERAS / 生理睡眠物質 / General anesthetic agents / Noradrenaline / Sleep Related Substance / ラット / サイトカイン / General anesthetics / EEG / Rat / Cytokine / 内因性睡眠関連物質 / 周術期管理 / 術後アウトカム / うつ病 / ケタミンン / In Vivo Ca2+イメージング / オプトジェネティクス / セル・アセンブリ / ケタミン / In vivo Ca2+ イメージング / In vivo Ca2+イメージング / 自律神経機能 / 炎症反応モデル / 局所麻酔薬 / 炎症反応 Less
  • Research Projects

    (25 results)
  • Research Products

    (128 results)
  • Co-Researchers

    (25 People)
  •  Clinical study for preoperative prediction of depression in older adult patients by deep learning and basic study for clarifying mechanism of depression and developing its prophylaxis.Principal Investigator

    • Principal Investigator
      廣田 和美
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55050:Anesthesiology-related
    • Research Institution
      Hirosaki University
  •  バーチャルリアリティを用いたプレハビリテーションプログラムによる術後譫妄予防Principal Investigator

    • Principal Investigator
      廣田 和美
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
    • Research Institution
      Hirosaki University
  •  うつ病病態発現神経回路の解明とケタミン抗うつ作用機序の検討

    • Principal Investigator
      二階堂 義和
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55050:Anesthesiology-related
    • Research Institution
      Hirosaki University
  •  ストレスコントロールを指向した周術期管理法の探求~局所麻酔薬の有用性~

    • Principal Investigator
      北山 眞任
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55050:Anesthesiology-related
    • Research Institution
      Hirosaki University
  •  術後アウトカム指向麻酔法の探求:内因性睡眠物質を応用した円滑な周術期管理への道標

    • Principal Investigator
      櫛方 哲也
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55050:Anesthesiology-related
    • Research Institution
      Hirosaki University
  •  Investigation of mechanism of pathogenesis of postoperative and sepsis-associated delirium and cognitive dysfunction and development of the prophylaxis.Principal Investigator

    • Principal Investigator
      HIROTA KAZUYOSHI
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Anesthesiology
    • Research Institution
      Hirosaki University
  •  Role of orexinergic neurons in sepsisPrincipal Investigator

    • Principal Investigator
      Hirota Kazuyoshi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Anesthesiology
    • Research Institution
      Hirosaki University
  •  Searching way of more gentle emergence from general anesthesia-An approach from anesthesiology and sleep to ERAS-

    • Principal Investigator
      Tetsuya KUSHIKATA
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology
    • Research Institution
      Hirosaki University
  •  麻酔後睡眠障害の治療戦略:睡眠ホメオスタシス調節の視点からのアプローチ

    • Principal Investigator
      吉田 仁
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology
    • Research Institution
      Hirosaki University
  •  Study on analgesic effects of neuropeptide SPrincipal Investigator

    • Principal Investigator
      HIROTA Kazuyoshi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Hirosaki University
  •  A study on the treatment of post anesthesia and surgical sleep disturbance

    • Principal Investigator
      KUSHIKATA Tetsuya
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Hirosaki University
  •  Sleep and general anesthesia : maintaining patient safety and improving the QOL during perioperative period

    • Principal Investigator
      YOSHIDA Hitoshi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Hirosaki University
  •  Stud for the mechanism of aging and anesthesia-related sleep disorder and its treatment.Principal Investigator

    • Principal Investigator
      HIROTA Kazuyoshi
    • Project Period (FY)
      2009 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Hirosaki University
  •  Study on a mechanism of emergence from general anesthesia-apply of the ascending arousal system for smooth recovery from general anesthesia

    • Principal Investigator
      KUSHIKATA Tetsuya
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Hirosaki University
  •  The effects of massage for symptom relief

    • Principal Investigator
      NOTO Yuka
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Fundamental nursing
    • Research Institution
      Hirosaki University
  •  生理活性物質ウロテンシンIIの全身麻酔および睡眠への関与Principal Investigator

    • Principal Investigator
      廣田 和美
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Hirosaki University
  •  The relationship between sleep and anesthesia as a clueto elucidate the mechanism of general anesthesia

    • Principal Investigator
      YOSHIDA Hitoshi
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Hirosaki University
  •  Brain orexinergic-noradrenergic neurons and mechanism of general anesthesiaPrincipal Investigator

    • Principal Investigator
      HIROTA Kazuyoshi
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Hirosaki University
  •  A study of post anesthetic and operative sleep disturbance. An approach to the mechanism and treatment on the disturbance.

    • Principal Investigator
      KUSHIKATA Tetsuya
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Hirosaki University
  •  全身麻酔中の低体温予防の研究-中枢性ノルエピネフリン作動性神経活性は関与するか

    • Principal Investigator
      MATSUKI Akitomo
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Hirosaki University
  •  Unitary mechanism of general anesthesia using brain noradrenergic neuronal network.Principal Investigator

    • Principal Investigator
      HIROTA Kazuyoshi
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Hirosaki University
  •  A study on the mechanism of General Anesthesia-inuduced sleep-relation to endogenous sleep related substances

    • Principal Investigator
      MATSUKI Akitomo
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Hirosaki University
  •  Contribution of L-type Voltage Sensitive Ca^<2+> Channels to Mechanism of General AnesthesiaPrincipal Investigator

    • Principal Investigator
      HIROTA Kazuyoshi
    • Project Period (FY)
      1997 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Hirosaki University
  •  向精神薬ドロペリドールの気管支拡張作用-超細臣ファイバースコープによる直視的判定法-Principal Investigator

    • Principal Investigator
      廣田 和美
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Hirosaki University
  •  喘息発作状態に対するNMDA受容体遮断薬の治療効果Principal Investigator

    • Principal Investigator
      廣田 和美
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Hirosaki University

All 2021 2020 2019 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 Other

All Journal Article Presentation

  • [Journal Article] Perioperative abnormal electroencephalography in a later-stage elderly with septic shock: a case report2021

    • Author(s)
      Kinoshita Hirotaka、Kushikata Tetsuya、Takekawa Daiki、Hirota Kazuyoshi
    • Journal Title

      JA Clinical Reports

      Volume: 7 Pages: 5-5

    • DOI

      10.1186/s40981-020-00409-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08807
  • [Journal Article] Is neurotransmitter release involved in the mechanism of general anesthesia?2020

    • Author(s)
      Hirota Kazuyoshi、Kushikata Tetsuya、Takekawa Daiki、Kudo Mihoko
    • Journal Title

      Journal of Anesthesia

      Volume: 34 Pages: 153-155

    • DOI

      10.1007/s00540-019-02718-1

    • NAID

      40022158227

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K08807
  • [Journal Article] Lower fractional exhaled nitric oxide levels are associated with depressive symptom in males: A population-based cross-sectional study2020

    • Author(s)
      Takekawa Daiki、Kudo Takashi、Saito Junichi、Nikaido Yoshikazu、Sawada Kaori、Takanashi Shingo、Hirota Kazuyoshi
    • Journal Title

      Psychiatry Research

      Volume: 293 Pages: 113453-113453

    • DOI

      10.1016/j.psychres.2020.113453

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K21623, KAKENHI-PROJECT-17H04319
  • [Journal Article] 術後せん妄・認知機能障害の予防と対策―最近のガイドラインから―2020

    • Author(s)
      廣田和美
    • Journal Title

      麻酔

      Volume: 69 Pages: 496-502

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04319
  • [Journal Article] Preoperative management and postoperative delirium: The possibility of neuroprehabilitation using virtual reality.2020

    • Author(s)
      Hirota K
    • Journal Title

      J Anesth.

      Volume: 34 Pages: 1-4

    • DOI

      10.1007/s00540-019-02660-2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04319
  • [Journal Article] 術後せん妄・認知機能障害の予防と対策―最近のガイドラインから―.2020

    • Author(s)
      廣田和美
    • Journal Title

      麻酔

      Volume: 69 Pages: 496-502

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K21623
  • [Journal Article] Pilot Study of Changes in Presepsin Concentrations Compared With Changes in Procalcitonin and C-Reactive Protein Concentrations After Cardiovascular Surgery2017

    • Author(s)
      Saito J, Hashiba E, Mikami A, Kudo T, Niwa H, Hirota K.
    • Journal Title

      Journal of Cardiothoracic and Vascular Anesthesia

      Volume: 17 Pages: 1262-1267

    • DOI

      10.1053/j.jvca.2017.02.007

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K10529, KAKENHI-PROJECT-15K15561
  • [Journal Article] Sepsis and the orexin system.2016

    • Author(s)
      Hirota K
    • Journal Title

      Journal of Anesthesia

      Volume: 30 Pages: 919-922

    • DOI

      10.1007/s00540-016-2246-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K15561
  • [Journal Article] Ketamine and propofol have opposite effects on postanesthetic sleep architecture in rats: relevance to the endogenous sleep-wakefulness substances orexin and melanin-concentrating hormone2016

    • Author(s)
      Kushikata T, Sawada M, Niwa H, Kudo T, Kudo M, Tonosaki M, Hirota K.
    • Journal Title

      Journal of anesthesia

      Volume: 30 Pages: 437-43

    • DOI

      10.1007/s00540-016-2161-x

    • NAID

      40020854416

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26462327
  • [Journal Article] Ketamine as an NMDA receptor antagonist]2013

    • Author(s)
      Kushikata T, Hirota K
    • Journal Title

      masui

      Volume: 62 Pages: 38-43

    • NAID

      40019551645

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592242
  • [Journal Article] Ketamine as an NMDA receptor antagonist2013

    • Author(s)
      Kushikata T, Hirota K
    • Journal Title

      Masui

      Volume: 62 Pages: 38-43

    • NAID

      40019551645

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592242
  • [Journal Article] Sleep in anesthesiology e What can we learn about anesthesia from studying sleep?2012

    • Author(s)
      Kushikata T, Yoshida Y, Hirota K
    • Journal Title

      Trends in Anaesthesia and Critical Care

      Volume: 2 Pages: 30-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592242
  • [Journal Article] Sleep in anesthesiology e What can we learn about anesthesia from studying sleep?2012

    • Author(s)
      Kushikata T, Yoshida H, Hirota K
    • Journal Title

      Trends in Anaesthesia and Critical Care

      Volume: 2 Pages: 30-35

    • DOI

      10.1016/j.tacc.2011.11.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592242
  • [Journal Article] Neuropeptide microdialysis in free-moving animals2011

    • Author(s)
      Kushikata T, Hirota K
    • Journal Title

      Methods Mol Biol

      Volume: 789 Pages: 261-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592242
  • [Journal Article] The effects of neuropeptide S on general anesthesia in rats2011

    • Author(s)
      Kushikata T, Yoshida H, Kudo M, Salvadori S, Calo G, Hirota K
    • Journal Title

      Anesth Analg

      Volume: 112 Pages: 845-849

    • DOI

      10.1213/ane.0b013e31820b990d

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390430
  • [Journal Article] Antinociceptive effects of neurotropin in a rat model of central neuropathic pain : DSP-4 induced noradrenergic lesion.2011

    • Author(s)
      Kudo T, Kushikata T, Kudo M, Kudo T, Hirota K
    • Journal Title

      Neurosci Lett

      Volume: 503 Pages: 20-22

    • DOI

      10.1016/j.neulet.2011.07.056

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390430
  • [Journal Article] Use of bispectral index monitoring for a patient with hepatic encephalopathy requiring living donor liver transplantation : a case report2011

    • Author(s)
      Okawa H, Ono T, Hashiba E, Tsubo T, Ishihara H, Hirota K
    • Journal Title

      J Anesth

      Volume: 25 Pages: 117-119

    • DOI

      10.1007/s00540-010-1055-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390430
  • [Journal Article] Antinociceptive effects of neurotropin in a rat model of central neuropathic pain: DSP-4 induced noradrenergic lesion2011

    • Author(s)
      Kudo T, Kushikata T, Kudo M, Kudo T, Hirota K. .
    • Journal Title

      Neurosci Lett

      Volume: :503 Pages: 20-2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592242
  • [Journal Article] Antinociceptive effects of neurotropin in a rat model of central neuropathic pain : DSP-4 induced noradrenergic lesion2011

    • Author(s)
      Kudo T, Kushikata T, Kudo T, Kudo M, Hirota K
    • Journal Title

      Neurosci Lett

      Volume: 503 Pages: 20-22

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390430
  • [Journal Article] Antinociceptive effects of neurotropin in a rat model of central neuropathic pain : DSP-4 induced noradrenergic lesion2011

    • Author(s)
      Kudo T, Kushikata T, Kudo M, Kudo T, Hirota K
    • Journal Title

      Neurosci Lett

      Volume: 503 Pages: 20-2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592242
  • [Journal Article] Role of coerulean noradrenergic neurones in general anaesthesia in rats2011

    • Author(s)
      Kushikata T, Yoshida H, Kudo M, Kudo T, Kudo T, Hirota K
    • Journal Title

      Br J Anaesth

      Volume: 107 Pages: 924-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592242
  • [Journal Article] Neuropeptide microdialysis in free-moving animals2011

    • Author(s)
      Kushikata T, Hirota K
    • Journal Title

      Methods Mol Biol

      Volume: 789 Pages: 261-269

    • DOI

      10.1007/978-1-61779-310-3_16

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390430
  • [Journal Article] Role of cerulean noradrenergic neurones in general anaesthesia in rats2011

    • Author(s)
      Kushikata T, Yoshida H, Kudo M, Kudo T, Kudo T, Hirota K
    • Journal Title

      Br J Anaesth

      Volume: 107 Pages: 924-929

    • DOI

      10.1093/bja/aer303

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390430
  • [Journal Article] The Effects of Neuropeptide S on General Anesthesia in Rats2011

    • Author(s)
      Kushikata T, Yoshida H, Kudo M, Salvadori S, Calo G, Hirota K
    • Journal Title

      Anesth Analg

      Volume: 112 Pages: 845-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592242
  • [Journal Article] A central neuropathic pain model by DSP-4 induced lesion of noradrenergic neurons : preliminary report.2010

    • Author(s)
      Kudo T, Kushikata T, Kudo M, Kudo T, Hirota K.
    • Journal Title

      Neurosci Lett

      Volume: 481 Pages: 102-104

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390430
  • [Journal Article] Changes in plasma orexin A during propofol-fentanyl anaesthesia in patients undergoing eye surgery2010

    • Author(s)
      Kushikata T, Yoshida H, Kudo M, Kudo T, Hirota K
    • Journal Title

      Br J Anaesth

      Volume: 104 Pages: 723-727

    • DOI

      10.1093/bja/aeq098

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390430
  • [Journal Article] The Effects of Neuropeptide S on General Anesthesia in Rats2010

    • Author(s)
      Kushikata T, Yoshida H, Kudo M, Salvadori S, Calo G, Hirota K
    • Journal Title

      Anesth Analg 112巻

      Pages: 845-849

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591797
  • [Journal Article] Plasma orexin A increases at emergence from sevoflurane-fentanyl anesthesia in patients undergoing ophthalmologic surgery.2010

    • Author(s)
      Kushikata T, Yoshida H, Kudo M, Kudo T, Hirota K
    • Journal Title

      Neurosci Lett

      Volume: 482 Pages: 212-215

    • DOI

      10.1016/j.neulet.2010.07.037

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390430
  • [Journal Article] Nitrous oxide and xenon increase noradrenaline release in the cerebral cortex in vivo and in vitro2010

    • Author(s)
      Yoshida H, Kushikata T, Tose R, Kudo M, Kudo T, Hirota K
    • Journal Title

      Neurosci Lett

      Volume: 469 Pages: 199-203

    • DOI

      10.1016/j.neulet.2009.11.074

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390430
  • [Journal Article] The Effects of Neuropeptide S on General Anesthesia in Rats2010

    • Author(s)
      Kushikata T, Yoshida H, Kudo M, Salvadori S , Cato G , Hirota K
    • Journal Title

      Anes thAnalg

      Volume: 112 Pages: 845-849

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591797
  • [Journal Article] Changes in plasma orexin A during propofol-fentanyl anaesthesia in patients unde rgoing eye surgery.2010

    • Author(s)
      Kushikata T, Yoshida H, Kudo M, Kudo T, Hirota K.
    • Journal Title

      Br J Anaesth

      Volume: 104 Pages: 723-727

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390430
  • [Journal Article] A central neuropathic pain model by DSP-4 induced lesion of noradrenergic neurons : preliminary report2010

    • Author(s)
      Kudo T, Kushikata T, Kudo M, Kudo T, Hirota K
    • Journal Title

      Neurosci Lett

      Volume: 481 Pages: 102-104

    • DOI

      10.1016/j.neulet.2010.06.061

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390430
  • [Journal Article] Plasma orexin A increases at emergence trom sevotlurane-tentanyl anesthesia in patients undergoing ophthalmologic surgery.2010

    • Author(s)
      Kushikata T, Yoshida H, Kudo M, Kudo T_ Hirota K.
    • Journal Title

      Neurosci Lett

      Volume: 482 Pages: 212-215

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390430
  • [Journal Article] The effects of benzodiazepines on urotensin II-stimulated norepinephrine release from rat cerebrocortical slices2009

    • Author(s)
      Kawaguchi Y, Ono T, Kudo M, Kushikata T, Hashiba E, Yoshida H, Kudo T, Furukawa K, Douglas SA, Hirota K
    • Journal Title

      Anesth Analg

      Volume: 108 Pages: 1177-1181

    • DOI

      10.1213/ane.0b013e3181981faa

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390430
  • [Journal Article] Interaction between orexinergic neurons and NMDA receptors in the control of locus coeruleus-cerebrocortical noradrenergic activity of the rat2009

    • Author(s)
      Tose R, Kushikata T, Yoshida H, Kudo M, Furukawa K, Ueno S, Hirota K
    • Journal Title

      Brain Res 1250巻

      Pages: 81-87

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591797
  • [Journal Article] Orexin A decreases ketamine-induced anesthesia time in the rat : the relevance to brain noradrenergic neuronal activity.2009

    • Author(s)
      Tose R, Kushikata T, Yoshida H, Kudo M, Furukawa K, Ueno S, Hirota K
    • Journal Title

      Anesth Analg. 108

      Pages: 491-495

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591797
  • [Journal Article] The effects of benzodiazepines on urotensin II-stimulated norepinephrine release from rat cerebrocortical slices.2009

    • Author(s)
      Kawaguchi Y, Ono T, Kudo M, Kushikata T, Hashiba E, Yoshida H, Kudo T, Furukawa K, Douglas SA, Hirota K.
    • Journal Title

      Anesthesia and Analgesia 108

      Pages: 1177-1181

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659395
  • [Journal Article] Orexin A decreases ketamine-induced anesthesia time in the rat : the relevance to brain noradrenergic neuronal activity2009

    • Author(s)
      Tose R, Kushikata T, Yoshida H, Kudo M, Furukawa K, Ueno S, Hirota K
    • Journal Title

      Anesth Analg 108巻

      Pages: 491-495

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591797
  • [Journal Article] Interaction between orexinergic neurons and NMDA receptors in the control oflocus coeruleus-cerebrocortical noradrenergic activity of the rat.2009

    • Author(s)
      Tose R, Kushikata T, Yoshida H, Kudo M, Furukawa K, Ueno S, Hirota K
    • Journal Title

      Brain Res. 1250

      Pages: 81-87

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591797
  • [Journal Article] Role of the orexinergic system in acute haemorrhage in the rat2008

    • Author(s)
      Hirota K, Kushikata T, Yoshida H, Kudo M, Kudo T.
    • Journal Title

      Neurosci Lett 432

      Pages: 162-166

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390423
  • [Journal Article] Noradrenergic neuronal network and mechanism of general anesthesia2008

    • Author(s)
      Hirota K, Kushikata T.
    • Journal Title

      Igaku No Ayumi (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390423
  • [Journal Article] Urotensin II evokes neurotransmitter release from rat cerebrocortical slices2008

    • Author(s)
      Ono T, Kawaguchi Y, Kudo M, Kushikata T, Hashiba E, Yoshida H, Kudo T, Furukawa K, Douglas SA, Guerrini R, Calo' G, Hirota K
    • Journal Title

      Neurosci Lett 440(3)

      Pages: 275-279

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659395
  • [Journal Article] Urotensin II evokes neurotransmitter release from rat cerebrocortical slices2008

    • Author(s)
      Ono T, Kawaguchi Y, Kudo M, Kushikata T, Hashiba E,Yoshida H, Kudo T, Furukawa K, Douglas SA, Guerrini R, Calo' G, Hirota K
    • Journal Title

      Neurosci Lett 440巻

      Pages: 275-279

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591797
  • [Journal Article] Urotensin II evokes neurotransmitter release from rat cerebrocortical slices2008

    • Author(s)
      Ono T, Kawaguchi Y, Kudo M, Kushikata T, Hashiba E, Yoshida H, Kudo T, Furukawa K, Douglas SA, Guerrini R, Calo G, Hirota K
    • Journal Title

      Neurosci Lett 440(3)

      Pages: 275-279

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591797
  • [Journal Article] Role of the orexinergic system in acute haemorrhage in the rat.2008

    • Author(s)
      Hirota K, Kushikata T, Yoshida H, Kudo M, Kudo T.
    • Journal Title

      Neurosci Lett 432

      Pages: 162-166

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390423
  • [Journal Article] ノルアドレナリン神経ネットワークと全身麻酔機序.2008

    • Author(s)
      廣田和美、櫛方哲也.
    • Journal Title

      医学の歩み (In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390423
  • [Journal Article] Anesthesia and sleep-Part 1. Recent findings of sleep2007

    • Author(s)
      Kushikata T, Yoshida H, Yasuda T, Tose Ryuji, Hirota Kazuyoshi, and Matsuki Akitomo
    • Journal Title

      Masui 56

      Pages: 1047-1052

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591608
  • [Journal Article] 麻酔と睡眠-第2部:麻酔と睡眠の関連について-2007

    • Author(s)
      櫛方哲也、吉田 仁、安田忠伸、遠瀬龍二、廣田和美、松木明知
    • Journal Title

      麻酔 56

      Pages: 1148-54

    • NAID

      40015650046

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17591608
  • [Journal Article] オレキシンとノルエピネフリン覚醒システム.2007

    • Author(s)
      廣田和美
    • Journal Title

      麻酔 56

      Pages: 9-18

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390423
  • [Journal Article] Effects of back massage on psychological status and salivary biomarkers2007

    • Author(s)
      Yuka Noto, Mihoko Kudo, Tetsumi Sato, Masako Ebina, and Kazuyoshi Hirota
    • Journal Title

      弘前医学 59巻

      Pages: 188-192

    • NAID

      110006602926

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592424
  • [Journal Article] Anesthesia and sleep-Part 2. On relationship between Sleep and Anesthesia2007

    • Author(s)
      Kushikata T, Yoshida H, Yasuda T, Tose Ryuji, Hirota Kazuyoshi, and Matsuki Akitomo
    • Journal Title

      Masui 56

      Pages: 1148-1154

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591608
  • [Journal Article] Orexinergic neurons and noradrenergic awakening system in general anesthesia2007

    • Author(s)
      Hirota K.
    • Journal Title

      Masui 56

      Pages: 9-18

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390423
  • [Journal Article] Effects of back massage on psychological status and salivary biomarkers2007

    • Author(s)
      Yuka Noto, Mihoko Kudo, Tetsumi Sato, Masako Ebina, and Kazuyoshi Hirota
    • Journal Title

      弘前医学 59

      Pages: 188-192

    • NAID

      110006602926

    • Data Source
      KAKENHI-PROJECT-19592424
  • [Journal Article] 麻酔と睡眠-第1部 : 睡眠に関する最近の知見-2007

    • Author(s)
      櫛方哲也、吉田 仁、廣田和美(他3名)
    • Journal Title

      麻酔 56

      Pages: 1047-1052

    • NAID

      40015624012

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591684
  • [Journal Article] 麻酔と睡眠-第2部:麻酔と睡眠の関連について-2007

    • Author(s)
      櫛方哲也、吉田仁、安田忠伸、遠瀬龍二、廣田和美、松木明知
    • Journal Title

      麻酔 56

      Pages: 1148-54

    • NAID

      40015650046

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17591608
  • [Journal Article] The effects of benzodiazepines on orexinergic systems in rat cerebrocortical slices.2007

    • Author(s)
      He Y, Kudo M, Kudo T, Kushikata T, Li E, Hirota K.
    • Journal Title

      Anesth Analg 104

      Pages: 338-340

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390423
  • [Journal Article] 麻酔と睡眠-第1部:睡眠に関する最近の知見2007

    • Author(s)
      櫛方哲也、吉田 仁、安田忠伸、遠瀬龍二、廣田和美、松木明知
    • Journal Title

      麻酔 56

      Pages: 1047-52

    • NAID

      40015624012

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17591608
  • [Journal Article] The effects of benzodiazepines on orexinergic systems in rat cerebrocortical slices2007

    • Author(s)
      He Y, Kudo M, Kudo T, Kushikata T, Li E, Hirota K.
    • Journal Title

      Anesth Analg 104

      Pages: 338-340

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390423
  • [Journal Article] オレキシンとノルエピネフリン覚醒システム.2007

    • Author(s)
      廣田和美.
    • Journal Title

      麻酔 56

      Pages: 9-18

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390423
  • [Journal Article] 麻酔と睡眠-第1部:睡眠に関する最近の知見2007

    • Author(s)
      櫛方哲也、吉田仁、安田忠伸、遠瀬龍二、廣田和美、松木明知
    • Journal Title

      麻酔 56

      Pages: 1047-52

    • NAID

      40015624012

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17591608
  • [Journal Article] 麻酔と睡眠-第2部 : 麻酔と睡眠の関連について-2007

    • Author(s)
      櫛方哲也、吉田 仁、廣田和美(他3名)
    • Journal Title

      麻酔 56

      Pages: 1148-1154

    • NAID

      40015650046

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591684
  • [Journal Article] Special cases: ketamine, nitrous oxide and xenon2006

    • Author(s)
      Hirota K.
    • Journal Title

      Best Pract Res Clin Anaesthesiol 202

      Pages: 69-79

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390423
  • [Journal Article] Special cases: ketamine, nitrous oxide and xenon.2006

    • Author(s)
      Hirota K.
    • Journal Title

      Best Pract Res Clin Anaesthesiol 202

      Pages: 69-79

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390423
  • [Journal Article] Special cases : ketamine, nitrous oxide and xenon.2006

    • Author(s)
      Hirota K, Kudo M, Tose R, et al.
    • Journal Title

      Best Pract Res Clin Anaesthesiol 20

      Pages: 69-79

    • Data Source
      KAKENHI-PROJECT-17390423
  • [Journal Article] Isoflurane increases norepinephrine release in the rat preoptic area and the posterior hypothalamus in vivo and in vitro : Relevance to thermoregulation during anesthesia.2005

    • Author(s)
      Kushikata T, Hirota K, Kotani N, Yoshida H, Kudo M, Matsuki A.
    • Journal Title

      Neuroscience 131

      Pages: 79-86

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370480
  • [Journal Article] Lack of interaction between orexinergic and alpha2-adrenergic neuronal systems in rat cerebrocortical slices.2005

    • Author(s)
      Hirota K, Kudo M, Tose R, Yoshida H, Kudo T, Kushikata T.
    • Journal Title

      Neurosci Lett 387

      Pages: 49-52

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370480
  • [Journal Article] Lack of interaction between orexinergic and alpha2-adrenergic neuronal systems in rat cerebrocortical slices2005

    • Author(s)
      Hirota K, Kudo M, Tose R, Yoshida H, Kudo T, Kushikata T.
    • Journal Title

      Neurosci Lett 387

      Pages: 49-52

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390423
  • [Journal Article] Lack of interaction between orexinergic and alpha2-adrenergic neuronal systems in rat cerebrocortical slices.2005

    • Author(s)
      Hirota K, Kudo M, Tose R, Yoshida H, Kudo T, Kushikata T.
    • Journal Title

      Neurosci Lett 387

      Pages: 49-52

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390423
  • [Journal Article] Isoflurane increases norepinephrine release in the rat preoptic area and the posterior hypothalamus in vivo and in vitro: Relevance to thermoregulation during anesthesia2005

    • Author(s)
      Kushikata T, Hirota K, Kotani N, Yoshida H, Kudo M, Matsuki A.
    • Journal Title

      Neuroscience 131

      Pages: 79-86

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390423
  • [Journal Article] Isoflurane increases norepinephrine release in the rat preoptic area and the posterior hypothalamus in vivo and in vitro: Relevance to thermoregulation during anesthesia.2005

    • Author(s)
      Kushikata T, Hirota K, Kotani N, Yoshida H, Kudo M, Matsuki A.
    • Journal Title

      Neuroscience 131

      Pages: 79-86

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390423
  • [Journal Article] Lack of interaction between orexinergic and α_2-adrenergic neuronal systems in rat cerebrocortical slices.2005

    • Author(s)
      Hirota K, Kudo M, Tose R, et al.
    • Journal Title

      Neuroscience Letters 387

      Pages: 49-52

    • Data Source
      KAKENHI-PROJECT-17390423
  • [Journal Article] Supraclinical concentrations of dexmedetomidine evoke norepinephrine release from rat cerebrocortical slices possible involvement of the orexin-1 receptor.2004

    • Author(s)
      Hirota K, Nomura H, Kudo M, Mori N, Kudo T, Kushikata T.
    • Journal Title

      Neurosci Lett 372

      Pages: 142-5

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370480
  • [Journal Article] Supraclinical concentrations of dexmedetomidine evoke norepinephrine release from rat cerebrocortical slices possible involvement of the orexin-1 receptor.2004

    • Author(s)
      Hirota K, Nomura H, Kudo M, et al.
    • Journal Title

      Neuroscience Letters 372

      Pages: 142-145

    • Data Source
      KAKENHI-PROJECT-14370480
  • [Journal Article] Role of noradrenergic and orexinergic neurons in general anaesthesia.2003

    • Author(s)
      Hirota K, Kushikata T, Kudo M.
    • Journal Title

      Current Neuropharmacology 1

      Pages: 333-40

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370480
  • [Journal Article] Effects of central hypocretin-1 administration on hemodynamic responses in young-adult and middle aged rats.2003

    • Author(s)
      Hirota K, Kushikata T, Kudo M, Kudo T, Smart D, Matsuki A.
    • Journal Title

      Brain Res 981

      Pages: 143-50

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370480
  • [Journal Article] Lade of an interaction between orexinergic and opioid/nociceptin systems in rat cerebrocortical slices.2003

    • Author(s)
      Hirota K, Kushikata T, Kudo M.Kudo T, Lambert DG, Smart D, Matsuki A.
    • Journal Title

      Neurosci Lett 340

      Pages: 173-176

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370480
  • [Journal Article] Orexinergic neuron and barbiturate anesthesia.2003

    • Author(s)
      Kushikata T, Hirota K, Yoshida H, Kudo M, Lambert DG, Smart D, Jerman JC, Matsuki A.
    • Journal Title

      Neuroscience 121

      Pages: 855-63

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370480
  • [Journal Article] Lack of an interaction between orexinergic and opioid/nociceptin systems in rat cerebrocortical slices.2003

    • Author(s)
      Hirota K, Kushikata T, Kudo M, Kudo T, Lambert DG, Smart D, Matsuki A.
    • Journal Title

      Neurosci Lett 340

      Pages: 173-6

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370480
  • [Journal Article] Inhibitory effects of intravenous anesthetic agents on K^+-evoked glutamate release from rat cerebrocortical slices. Involvement of voltage sensitive Ca^<2+> channels and GABA_A receptors.2002

    • Author(s)
      Kitayama M, Hirota K, Kudo M, Kudo T, Ishihara H, Matsuki A.
    • Journal Title

      Naunyn Schmiedbergs Arch Pharmacol 366

      Pages: 246-53

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370480
  • [Journal Article] Alpha-2 adrenoceptor activity affects propofol-induced sleeping time.2002

    • Author(s)
      Kushikata T, Hirota K, Yoshida H, Kubota T, Ishihara H, Matsuki A.
    • Journal Title

      Anesth Analg 94

      Pages: 1201-6

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370480
  • [Presentation] 高齢化社会における術後譫妄・認知機能障害予防戦略~早期覚醒と周術期の患者管理・評価の重要性~2020

    • Author(s)
      廣田和美
    • Organizer
      日本臨床麻酔学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04319
  • [Presentation] 高齢化社会における術後譫妄・認知機能障害予防戦略~早期覚醒と周術期の患者管理・評価の重要性~2020

    • Author(s)
      廣田和美
    • Organizer
      日本臨床麻酔学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K21623
  • [Presentation] 高齢化社会における安全な周術期管理 -術後せん妄対策2020

    • Author(s)
      廣田和美
    • Organizer
      日本臨床モニター学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K21623
  • [Presentation] LPS投与による睡眠障害にオレキシン作動性神経は関与するか-Orexin/Ataxin-3 transgenic ratを用いた研究2020

    • Author(s)
      竹川大貴、櫛方哲也、二階堂義和、木下裕貴、大山翼、廣田和美
    • Organizer
      第24回日本神経麻酔集中治療学会(Web開催)
    • Data Source
      KAKENHI-PROJECT-18K08807
  • [Presentation] 高齢化社会における安全な周術期管理 -術後せん妄対策2020

    • Author(s)
      廣田和美
    • Organizer
      日本臨床モニター学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04319
  • [Presentation] 敗血症性ショック高齢患者の脳波モニタリング:症例報告2020

    • Author(s)
      木下裕貴、櫛方哲也、大山翼、竹川大貴、紺野真緒、廣田和美
    • Organizer
      第24回日本神経麻酔集中治療学会(Web開催)
    • Data Source
      KAKENHI-PROJECT-18K08807
  • [Presentation] Involvement of meurodegenerative and neuroinflammatory processes in the pathogenesis of postoperative delirium in elderly mice.2019

    • Author(s)
      Nikaido Y, Tatara Y, Kushikata T, Hirota K.
    • Organizer
      Hirosaki Medical Science Forum
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04319
  • [Presentation] Investigation of the effect of perioperative inflammation on electroencephalogram2019

    • Author(s)
      Hirotaka Kinoshita, Tetsuya Kushikata, Daiki Takekawa, Kazuyoshi Hirota
    • Organizer
      The 6th Congress of Asian Society for Neuroanesthesia and Critical Care
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04319
  • [Presentation] 敗血症患者における血中オレキシン濃度の変化の検討.2017

    • Author(s)
      赤石真啓、橋場英二、天内絵理香、太田大地、櫛方哲也、廣田和美.
    • Organizer
      日本麻酔科学会第64回学術集会
    • Data Source
      KAKENHI-PROJECT-15K15561
  • [Presentation] Orexinergic tone affects survival in sepsis in rats.2017

    • Author(s)
      Hirota K, Takekawa D, Kushikata T, Kudo M.
    • Organizer
      BJA Research Forum Winter Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15561
  • [Presentation] ケタミンの麻酔・鎮痛機序におけるオレキシン作動性神経の関与は異なる。-オレキシン遺伝子改変ラット(OX/ATA3 TG rat)を用いた研究-2016

    • Author(s)
      外崎 充、櫛方哲也、丹羽英智、齋藤淳一、工藤隆司、廣田和美
    • Organizer
      日本麻酔科学会第63回学術集会
    • Place of Presentation
      福岡国際会議場(福岡県、福岡市)
    • Year and Date
      2016-05-26
    • Data Source
      KAKENHI-PROJECT-26462327
  • [Presentation] Ketamine disturbs post anesthesia sleep in aged rat&#8211;relevance to brain Orexin contents?2015

    • Author(s)
      Tetsuya KUSHIKATA, MD, Ph. D, Izumi Miki, B Sc, Mitsuru Tonosaki , MD, Hidetomo Niwa, MD, Ph. D, Jyunichi Saito, MD, Ph. D, Kazuyoshi HIROTA, MD, Ph. D, FRCA
    • Organizer
      The 9th lnternationaI Conference on Mechanisms of Anaesthesia
    • Place of Presentation
      ボン市、ドイツ
    • Year and Date
      2015-06-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462327
  • [Presentation] ニューロペプチドSの鎮痛作用は下行性抑制系が関与する2014

    • Author(s)
      地主継、櫛方哲也、廣田和美、他
    • Organizer
      日本麻酔科学会第61回学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2014-05-01
    • Data Source
      KAKENHI-PROJECT-24659690
  • [Presentation] 内因性神経ペプチドNeuropeptide Sは睡眠リズム形成に関与する-ラットにおけるアンタゴニストを用いた研究-2014

    • Author(s)
      大石将文、櫛方哲也、丹羽英智、矢越ちひろ、小笠原千尋、廣田和美
    • Organizer
      日本麻酔科学会第61回学術集会
    • Place of Presentation
      横浜市
    • Data Source
      KAKENHI-PROJECT-23592242
  • [Presentation] オレキシンによる交感神経制御(Tgラットによる循環系評価)2013

    • Author(s)
      村上学、櫛方哲也、丹羽英智、大場貴喜、尾野恭一、廣田和美
    • Organizer
      第45回東北生理談話会
    • Place of Presentation
      仙台
    • Year and Date
      2013-10-05
    • Data Source
      KAKENHI-PROJECT-23592242
  • [Presentation] 全身麻酔薬による鎮静、鎮痛機序-ノルアドレナリン作動性神経系から見た提言-2013

    • Author(s)
      櫛方哲也、廣田和美
    • Organizer
      第60回日本麻酔科学会
    • Place of Presentation
      札幌
    • Year and Date
      2013-05-24
    • Data Source
      KAKENHI-PROJECT-23592242
  • [Presentation] プロポフォ-ル麻酔後のレム睡眠減少にMelanin-Concentrating Hormone(MCH)が関与する2013

    • Author(s)
      澤田匡宏、櫛方哲也、地主継、工藤隆司、外崎充、廣田和美
    • Organizer
      第60回日本麻酔科学会
    • Place of Presentation
      札幌
    • Year and Date
      2013-05-23
    • Data Source
      KAKENHI-PROJECT-23592242
  • [Presentation] 麻酔と睡眠-麻酔からの覚醒について-2012

    • Author(s)
      櫛方哲也、廣田和美
    • Organizer
      第37回日本睡眠学会
    • Place of Presentation
      横浜
    • Year and Date
      2012-06-30
    • Data Source
      KAKENHI-PROJECT-23592242
  • [Presentation] シンポジウムS37 麻酔と睡眠-麻酔からの覚醒について-2012

    • Author(s)
      櫛方哲也、廣田和美
    • Organizer
      日本睡眠学会第37回定期学術集会
    • Place of Presentation
      横浜市
    • Invited
    • Data Source
      KAKENHI-PROJECT-23592242
  • [Presentation] 麻酔と睡眠-麻酔からの覚醒について-2012

    • Author(s)
      櫛方哲也,廣田和美
    • Organizer
      第37回日本睡眠学会
    • Place of Presentation
      横浜
    • Year and Date
      2012-06-30
    • Data Source
      KAKENHI-PROJECT-21390430
  • [Presentation] 麻酔と睡眠 -麻酔からの覚醒について-2012

    • Author(s)
      櫛方哲也、廣田和美
    • Organizer
      日本睡眠学会第37回定期学術集会
    • Place of Presentation
      横浜市
    • Data Source
      KAKENHI-PROJECT-21390430
  • [Presentation] 脳内ノルアドレナリン神経網と麻酔および意識との関係2011

    • Author(s)
      廣田和美
    • Organizer
      第20回日本意識障害学会
    • Place of Presentation
      弘前
    • Year and Date
      2011-09-02
    • Data Source
      KAKENHI-PROJECT-21390430
  • [Presentation] Neuropeptide S attenuates increase in REM sleep following ketamine anesthesia2011

    • Author(s)
      Kushikata T, Calo' G, Moriya K, Oishi M, Yakoshi C, Hirota K
    • Organizer
      8th World Congress of Neuroscience by International Brain Organization
    • Place of Presentation
      フローレンス,イタリア共和国
    • Data Source
      KAKENHI-PROJECT-21390430
  • [Presentation] Neuropeptide S attenuates increase in REM sleep following ketamine anesthesia2011

    • Author(s)
      Kushikata T, Calo'G, Moriya K, Oishi M, Yakoshi C, Hirota K
    • Organizer
      8th World Congress of Neuroscience by International Brain Organization
    • Place of Presentation
      フローレンス市、イタリア共和国
    • Data Source
      KAKENHI-PROJECT-21390430
  • [Presentation] Ketamine modified Melanin-Concentrating Hormone in rat brain2011

    • Author(s)
      Kushikata T, Sawada M, Oishi M, Moriya K, Yoshida H, Hirota K
    • Organizer
      Worldsleep 2011
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-21390430
  • [Presentation] Ketamine modified Melanin-Concentrating Hormone in rat brain2011

    • Author(s)
      Kushikata T, Sawada M, Oishi M, Moriya K, Yoshida H, Hirota K
    • Organizer
      Worldsleep2011
    • Place of Presentation
      京都市、日本
    • Data Source
      KAKENHI-PROJECT-21390430
  • [Presentation] Orexin reduced ketamine anesthesia-induced sleep disturbance2010

    • Author(s)
      Kushikata T, Hirota K
    • Organizer
      Neuro-Talk-2010
    • Place of Presentation
      シンガポール共和国
    • Data Source
      KAKENHI-PROJECT-21390430
  • [Presentation] Ketamine affects brain orexin A contents in rats2010

    • Author(s)
      Oishi M, Moriya K, Saito C, Kudo M, Kushikata T, Hirota K
    • Organizer
      12th Meeting of Hirosaki International Forum of Medical Science
    • Place of Presentation
      弘前
    • Year and Date
      2010-10-30
    • Data Source
      KAKENHI-PROJECT-21390430
  • [Presentation] Orexin reduced ketamine anesthesia-induced sleep disturbance.2010

    • Author(s)
      Kushikata T, Hirota K.
    • Organizer
      Neuro-Talk 2010
    • Place of Presentation
      Singapore
    • Data Source
      KAKENHI-PROJECT-21390430
  • [Presentation] I Ketamine affects brain orexin A contents in rats.2010

    • Author(s)
      Oishi M, Moriya K, Saito C, Kudo M, Kushikata T, Hirota K.
    • Organizer
      12<th> Meeting of Hirosaki International Forum of Medical Science
    • Place of Presentation
      Hirosaki
    • Year and Date
      2010-10-30
    • Data Source
      KAKENHI-PROJECT-21390430
  • [Presentation] Effects of ketamine anaesthesia on brain orexin A contents in rats2010

    • Author(s)
      Hirota K
    • Organizer
      Winter Scientific Meeting of the Anaesthetic Research Society
    • Place of Presentation
      ロンドン,連合王国
    • Year and Date
      2010-11-12
    • Data Source
      KAKENHI-PROJECT-21390430
  • [Presentation] 青斑核由来の脳内ノルアドレナリン作動性神経活性はチオペンタール麻酔機序に関与する2010

    • Author(s)
      櫛方哲也、吉田仁、丹羽英智、工藤隆司、和田盛人、廣田和美
    • Organizer
      第57回日本麻酔科学会
    • Place of Presentation
      福岡
    • Year and Date
      2010-06-04
    • Data Source
      KAKENHI-PROJECT-21390430
  • [Presentation] Orexin decreased ketamine anesthesia-induced sleep disturbance2010

    • Author(s)
      Kushikata T, Oishi M, Moriya K, Saito C, Yoshida H, Hirota K
    • Organizer
      12th Meeting of Hirosaki International Forum of Medical Science
    • Place of Presentation
      弘前
    • Year and Date
      2010-10-30
    • Data Source
      KAKENHI-PROJECT-21390430
  • [Presentation] Preoperative cerebral infarction causesbispectral index asymmetry2009

    • Author(s)
      吉田 仁、櫛方哲也、廣田和美(他3名)
    • Organizer
      International Anesthesia Research Society 2009 Annual Meeting
    • Place of Presentation
      アメリカ合衆国サンディエゴ
    • Year and Date
      2009-03-16
    • Data Source
      KAKENHI-PROJECT-18591684
  • [Presentation] 進行がん患者のリンパ浮腫ケアの効果2008

    • Author(s)
      野戸結花、浅利三和子、佐藤哲観、蝦名正子、丹羽英智、工藤美穂子、廣田和美、阿部由直
    • Organizer
      第13回日本緩和医療学会学術大会
    • Place of Presentation
      静岡
    • Year and Date
      2008-07-05
    • Data Source
      KAKENHI-PROJECT-19592424
  • [Presentation] Orexin decreased ketamine anesthesia time in rat. -Relevance to brain noradrenergic neuronal activity2006

    • Author(s)
      Tose R, Kushikata T, Yoshida H, Yasuda, Kudo M, Hirota K.
    • Organizer
      80th Clinical and Scientific Congress of International A nesthesia Research Society,
    • Place of Presentation
      San Francisco
    • Year and Date
      2006-03-26
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390423
  • [Presentation] Orexin decreased ketamine anesthesia time in rat. -Relevance to brain noradrenergic neuronal activity2006

    • Author(s)
      Tose R, Kushikata T, Yoshida H, Yasuda, Kudo M, Hirota K.
    • Organizer
      80th Clinical and Scientific Congress of International Anesthesia Research Society
    • Place of Presentation
      San Francisco
    • Year and Date
      2006-03-26
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390423
  • [Presentation] 亜酸化窒素の大脳皮質ノルアドレナリン放出に与える影響.2006

    • Author(s)
      吉田仁、櫛方哲也、遠瀬龍二、工藤美穂子、石原弘規、廣田和美
    • Organizer
      第53回日本麻酔科学会総会
    • Place of Presentation
      神戸
    • Year and Date
      2006-06-01
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390423
  • [Presentation] Plasma orexin A increases by hemorrhagic shock2006

    • Author(s)
      Kushikata T, Hirota K, Yoshida H, Tose R, Kudo M.
    • Organizer
      The 53th Annual Meeting of Japan Society of. Anesthesiolohists
    • Place of Presentation
      Kobe
    • Year and Date
      2006-06-01
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390423
  • [Presentation] オレキシンがケタミンン麻酔に与える影響-ノルアドレナリン作動性神経活性との関連において-.2006

    • Author(s)
      遠瀬龍二、櫛方哲也、吉田仁、安田忠伸、工藤美穂子、工藤剛、廣田和美
    • Organizer
      第53回日本麻酔科学会総会
    • Place of Presentation
      神戸
    • Year and Date
      2006-06-01
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390423
  • [Presentation] Effects of nitrous oxide on noradrenaline release from the cerebral cortex in rats2006

    • Author(s)
      Yoshida H, Kushikata T, Tose R, Kudo M, Ishihara H, Hirota K.
    • Organizer
      The 53th Annual Meeting of Japan Society of Anesthesiolohists
    • Place of Presentation
      Kobe
    • Year and Date
      2006-06-01
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390423
  • [Presentation] Effects of orexin on ketamine anesthesia. The relation with activity of noradrenergic neurons2006

    • Author(s)
      Tose R, Kushikata T, Yoshida H, Yasuda T, Kudo M, Kudo T, Hirota K.
    • Organizer
      The 53th Annual Meeting of Japan Society of Anesthesiolohists
    • Place of Presentation
      Kobe
    • Year and Date
      2006-06-01
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390423
  • [Presentation] 出血性ショックは血漿中のオレキシンA(OXA)濃度を増加させる.-オレキシン受容体拮抗薬SB-334867を用いた研究-.2006

    • Author(s)
      櫛方哲也、廣田和美、吉田仁、遠瀬龍二、工藤美穂子
    • Organizer
      第53回日本麻酔科学会総会
    • Place of Presentation
      神戸
    • Year and Date
      2006-06-01
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390423
  • [Presentation] The effects of benzodiazepines on orexinergic systems in rat cerebrocortical slices2005

    • Author(s)
      Kushikata T, Kudo M, Kudo T, Hirota K.
    • Organizer
      The 12^<th> Japan Society for Intravenous Anesthesia And Infusion Technology
    • Place of Presentation
      Chiba
    • Year and Date
      2005-12-10
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390423
  • [Presentation] オレキシン作動性神経とアルファ2受容体の相互作用の欠如について.2005

    • Author(s)
      櫛方哲也、遠瀬龍二、吉田仁、廣田和美.
    • Organizer
      第52回日本麻酔科学会総会
    • Place of Presentation
      神戸
    • Year and Date
      2005-06-01
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390423
  • [Presentation] Lack of interaction between orexinergic and alpha2-adrenergic neuronal systems in rat cerebrocortical slices2005

    • Author(s)
      Kushikata T, Tose R, Yoshida H, Hirota K.
    • Organizer
      The 52th Annual Meeting of Japan Society of Anesthesiolohists
    • Place of Presentation
      Kobe
    • Year and Date
      2005-06-01
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390423
  • [Presentation] オレキシンによるラット大脳皮質スライスからの選択的ノルエピネフリン放出に対するベンゾジアゼピンの抑制効果.2005

    • Author(s)
      櫛方哲也、工藤美穂子、工藤剛、廣田和美
    • Organizer
      第12回日本静脈麻酔・Infusion Technology研究会
    • Place of Presentation
      千葉
    • Year and Date
      2005-12-10
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390423
  • [Presentation] オレキシン作動性神経はケタミンの鎮痛作用に関与する-Transgenic Rat(OX/ATA3 TG rat)を用いた研究-

    • Author(s)
      外崎充、櫛方哲也、佐々木剛範、丹羽英智、廣田和美、工藤隆司
    • Organizer
      公益社団法人日本麻酔科学会 第 61回学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2014-05-15 – 2014-05-17
    • Data Source
      KAKENHI-PROJECT-26462327
  • 1.  KUSHIKATA Tetsuya (80250603)
    # of Collaborated Projects: 20 results
    # of Collaborated Products: 103 results
  • 2.  KUDO Mihoko (30003411)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 58 results
  • 3.  YOSHIDA Hitoshi (00374843)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 51 results
  • 4.  二階堂 義和 (50613478)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 3 results
  • 5.  KUDO Tsuyoshi (70003407)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 30 results
  • 6.  KUDO Takashi (40613352)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 7.  橋場 英二 (10374844)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 4 results
  • 8.  斎藤 淳一 (90647413)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 9.  OKAWA Hirobumi (40322953)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 10.  MATSUKI Akitomo (20003543)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  丹羽 英智 (20374845)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 12.  KUBOTA Takeshi
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  NOTO Yuka (80250629)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 14.  SATO Tetsumi (30281934)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 15.  KITAJIMA Maiko (70455731)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  小谷 直樹 (30205405)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  上野 伸哉 (00312158)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  村上 学 (80302090)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  北山 眞任 (80374841)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  中井 希紫子 (60645266)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  佐々木 賀広 (70178672)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  竹川 大貴 (80834803)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  畠山 真吾 (10400136)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  大山 力 (80282135)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  安沢 則之
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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