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KANDA Shigeru  神田 滋

ORCIDConnect your ORCID iD *help
… Alternative Names

神田 滋  カンダ シゲル

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Researcher Number 20244048
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2006: Nagasaki University, Graduate School of Biomedical Sciences, Department of Molecular Microbiology and Immunology, Research Associate, 大学院医歯薬学総合研究科, 客員研究員
2002 – 2005: Nagasaki University Graduate School of Medical Science Department of Molecular Microbiology and Immunology, Associate Professor, 大学院・医歯薬学総合研究科, 助教授
2001: 長崎大学, 大学院・研究科, 助教授
2000 – 2001: Graduate School of Medicine, Nagasaki University Associate Professor, 大学院・医学研究科, 助教授
1999: 長崎大学, 医学部・附属病院, 助手 … More
1997: 長崎大学, 医学部附属病院, 助手
1996: 長崎大学, 医学部, 助手
1993: 長崎大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Urology / Urology
Except Principal Investigator
Urology
Keywords
Principal Investigator
FGF-2 / Fes / c-Fyn / c-Fes / endothelial cells / 血管内皮細胞 / Src / 血管新生 / hypoxia / angiopoietin 1 … More / HGF / PEDF / Rho / Fyn / シグナル伝達 / sonic hedgehog / stromal cell-derived factor-1 / tube formation / angiogenesis / FGF / 管腔形成 / c-Src / Molecular targeting therapy / Antiangiogenic therapy / 低酸素 / angiopoletin 1 / 分子標的療法 / 血管新生阻害療法 / signal transduction / differentiation / フィブロネクチン / c-Akt / PI3-キナーゼ / 分化 / Tie2 / anti-angiogenic therapy / fibroblast growth factor receptor / MAPキナーゼ / 遊走 / 抗血管新生療法 / 線維芽細胞増殖因子受容体 … More
Except Principal Investigator
Paclitaxel / Angiogenin / PD-ECGF / 腎細胞癌 / Renal cell carcinoma / Tumors / Cyclooxygenase / Arachidonic acid / 悪性腫瘍 / シクロオキシゲナーゼ / アラキドン酸代謝 / Signal transduction / Bladder preservatiopn therapy / Locally advanced bladder cancer / Neovascularization / Superficial bladder cancer / VEGF / hTERTmRNA / NMP-22 / angiogenin / PDECGF / 膀胱癌 / シグナル伝達 / 温存療法 / 局所浸潤性膀胱癌 / 血管新生 / 表在性膀胱癌 / 腎臓 / 腎再生 / 急性腎不全 / 骨形成因子 / 代償性腎成長 / 塩基性線維芽細胞成長因子 Less
  • Research Projects

    (8 results)
  • Research Products

    (42 results)
  • Co-Researchers

    (7 People)
  •  Study of endothelial cell-specific signal transduction pathways and effect of chronic hypoxia. A strategy for the development of an effective antiangiogenic therapy.Principal Investigator

    • Principal Investigator
      KANDA Shigeru
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Nagasaki University
  •  Identification of endothelial cell-specific signal transduction pathways leading to angiogenesisPrincipal Investigator

    • Principal Investigator
      KANDA Shigeru
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Nagasaki University
  •  Identification of endothelial cell-specific signal transaction pathways leading to angiogenic cellular responsesPrincipal Investigator

    • Principal Investigator
      KANDA Shigeru
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Urology
    • Research Institution
      Nagasaki University Graduate School of Medical Science
  •  The effects of arachidonic acid on urological tumors

    • Principal Investigator
      KOGA Shigehiko
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Nagasaki University Graduate School of Medical Science
  •  Prognostic significance of angiogenic growth factor in superficial bladder cancer

    • Principal Investigator
      KANETAKE hiroshi
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Nagasaki University
  •  Identification of the target molecules for antiangiogenic therapyPrincipal Investigator

    • Principal Investigator
      KANDA Shigeru
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Nagasaki University
  •  骨形成因子の腎への影響の検討

    • Principal Investigator
      斉藤 泰
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Urology
    • Research Institution
      Nagasaki University
  •  腎細胞癌増殖における塩基性線維芽細胞増殖因子の役割

    • Principal Investigator
      KANETAKE hiroshi
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Nagasaki University

All 2007 2006 2005 2004 2003 Other

All Journal Article Book

  • [Book] Trends in Angiogenesis Research.2005

    • Author(s)
      Kanda, S., Miyata, Y., Kanetake, H.
    • Publisher
      Studies of the endothelial cell-specific signal transduction pathways. New paradigm for the development of potent anti-angiogenic therapies.
    • Data Source
      KAKENHI-PROJECT-17591686
  • [Book] Progress in Angiogenesis Research2005

    • Author(s)
      Kanda, Y.Miyata, H.Kanetake
    • Publisher
      Nova Science Publishers, Inc. Hauppauge, NY, USA.(In press)
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591698
  • [Book] Progress in Angiogenesis Research2005

    • Author(s)
      Kanda, Y.Miyata, H.Kanetake
    • Publisher
      (in press)
    • Data Source
      KAKENHI-PROJECT-15591698
  • [Book] Trends in Angiogenesis Research2005

    • Author(s)
      Shigeru Kanda, et al.
    • Total Pages
      254
    • Publisher
      Nova Science Publishers, Inc; New York
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591686
  • [Journal Article] シグナル伝達分子に対する分子標的療法の現況と将来の展望2007

    • Author(s)
      神田 滋, 正野武文, 宮田康好, 金武洋
    • Journal Title

      西日本泌尿器科 69(3)(印刷中)

    • Data Source
      KAKENHI-PROJECT-17591686
  • [Journal Article] Role of Src in angiopoietin 1-induced capillary morphogenesis of endothelial cells : Effect of chronic hypoxia on Src inhibition by PP2.2007

    • Author(s)
      Kanda S, Kanetake H, Miyata Y.
    • Journal Title

      Cellular Signaling 19(3)

      Pages: 472-80

    • NAID

      120006983943

    • Data Source
      KAKENHI-PROJECT-17591686
  • [Journal Article] Role of Src in angiopoietin 1-induced capillary morphogenesis of endothelial cells : Effect of chronic hypoxia on Src inhibition by PP2.2007

    • Author(s)
      Shigeru Kanda, et al.
    • Journal Title

      Cellular Signaling 19(3)

      Pages: 472-480

    • NAID

      120006983943

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591686
  • [Journal Article] Role of Src in angiopoietin 1-induced capillary morphogenesis of endothelial cells : Effect of chronic hypoxia on Src inhibition by PP2.2007

    • Author(s)
      Shigeru Kanda et al.
    • Journal Title

      Cellular Signaling. 19(3)

      Pages: 472-80

    • NAID

      120006983943

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591686
  • [Journal Article] HGF-induced capillary morphogenesis of endothelial cells is regulated by Src.2006

    • Author(s)
      Shigeru Kanda, et al.
    • Journal Title

      Biochemical and Biophysical Research Communications 344(2)

      Pages: 617-622

    • NAID

      120006983940

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591686
  • [Journal Article] Current status and perspective of antioangiogenic therapy for cancer : urinary cancer (REVIEW).2006

    • Author(s)
      Shigeru Kanda, et al.
    • Journal Title

      International Journal of Clinical Oncology 11(2)

      Pages: 90-107

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591686
  • [Journal Article] Fibroblast growth factor-2 induces the activation of Src through Fes, which regulates focal adhesion disassembly.2006

    • Author(s)
      Shigeru Kanda, et al.
    • Journal Title

      Experimental Cell Research. 312(16)

      Pages: 3015-22

    • NAID

      120006983942

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591686
  • [Journal Article] Fibroblast growth factor-2 induces the activation of Src through Fes, which regulates focal adhesion disassembly.2006

    • Author(s)
      Shigeru Kanda, et al.
    • Journal Title

      Experimental Cell Research 312(16)

      Pages: 3015-3022

    • NAID

      120006983942

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591686
  • [Journal Article] levated expression of ERK 2 in human tumor cells chronically treated with PD98059.2006

    • Author(s)
      Kanda S, Kanetake H, Miyata Y.
    • Journal Title

      Biochemical and Biophysical Research Communications 345(4)

      Pages: 1481-6

    • Data Source
      KAKENHI-PROJECT-17591686
  • [Journal Article] HGF-induced capillary morphogenesis of endothelial cells in regulated by Src.2006

    • Author(s)
      Kanda S, Kanetake H, Miyata Y.
    • Journal Title

      Biochemical and Biophysical Research Communications 344(2)

      Pages: 617-22

    • Data Source
      KAKENHI-PROJECT-17591686
  • [Journal Article] Fibroblast growth factor-2 induces the activation of Src through Fes, which regulates focal adhesion disassembly.2006

    • Author(s)
      Kanda S, Miyata Y, Kanetake H, Smithgall TE.
    • Journal Title

      Experimental Cell Research 312(16)

      Pages: 3015-22

    • NAID

      120006983942

    • Data Source
      KAKENHI-PROJECT-17591686
  • [Journal Article] Current status and perspective of antiangiogenic therapy for cancer : urinary cancer (REVIEW).2006

    • Author(s)
      Shigeru Kanda et al.
    • Journal Title

      International Journal of Clinical Oncology. 11(2)

      Pages: 90-107

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591686
  • [Journal Article] Elevated expression of ERK 2 in human tumor cells chronically treated with PD98059.2006

    • Author(s)
      Shigeru Kanda, et al.
    • Journal Title

      Biochemical and Biophysical Research Communications 345(4)

      Pages: 1481-1486

    • NAID

      120006983941

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591686
  • [Journal Article] Current status and perspective of antiangiogenic therapy for cancer : urinary cancer.2006

    • Author(s)
      Kanda S, Miyata Y, Kanetake H.
    • Journal Title

      International Journal of Clinical Oncology 11(2)

      Pages: 90-107

    • NAID

      10018174756

    • Data Source
      KAKENHI-PROJECT-17591686
  • [Journal Article] T-cell factor-4-dependent up-regulation of fibronectin is involved in fibroblast growth factor-2-induced tube formation by endothelial cells.2005

    • Author(s)
      S.Kanda, Y.Miyata, H.Kanetake
    • Journal Title

      Journal of Cellular Biochemistry 94

      Pages: 835-847

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591698
  • [Journal Article] Pigment epithelium-derived factor inhibits fibroblast growth factor-2-induced capillary morphogenesis of endothelial cells through c-Fyn.2005

    • Author(s)
      Shigeru Kanda, et al.
    • Journal Title

      Journal of Cell Science 118(Pt 5)

      Pages: 961-970

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591686
  • [Journal Article] Pigment epithelium-derived factor inhibits fibroblast growth factor-2-induced capillary morphogenesis of endothelial cells through c-Fyn.2005

    • Author(s)
      Shigeru Kanda, Yasushi Mochizuki, Takao Nakamura, Yasuyoshi Miyata, Toshifumi Matsuyama, Hiroshi Kanetake
    • Journal Title

      Journal of Cell Science 118

      Pages: 961-970

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591698
  • [Journal Article] Aniopoietin 1 is mitogenic for cultured endothelial cells.2005

    • Author(s)
      Shigeru Kanda, et al.
    • Journal Title

      Cancer Research 65

      Pages: 6820-6827

    • Data Source
      KAKENHI-PROJECT-17591686
  • [Journal Article] Aniopoietin 1 is mitogenic for cultured endothelial cells.2005

    • Author(s)
      Shigeru Kanda, et al.
    • Journal Title

      Cancer Research 65(15)

      Pages: 6820-6827

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591686
  • [Journal Article] T-cell factor-4-dependent up-regulation of fibronectin is involved in fibroblast growth factor-2-induced tube formation by endothelial cells.2005

    • Author(s)
      Shigeru Kanda, et al.
    • Journal Title

      Journal of Cellular Biochemistry 94

      Pages: 835-847

    • Data Source
      KAKENHI-PROJECT-17591686
  • [Journal Article] Pigment epithelium-derived factor inhibits fibroblast growth factor-2-induced capillary morphogenesis of endothelial cells through c-Fyn2005

    • Author(s)
      S.Kanda, Y.Mochizuki, T.Nakamura, Y.Miyata, T.Matsuyama, H.Kanetake
    • Journal Title

      Journal of Cell Science 118

      Pages: 961-970

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591698
  • [Journal Article] T-cell factor-4-dependent up-regulation of fibronectin is involved in fibroblast growth factor-2-induced tube formation by endothelial cells.2005

    • Author(s)
      Shigeru Kanda, Yasuyoshi Mityata, Hiroshi Kanetake
    • Journal Title

      Journal of Cellular Biochemistry 94

      Pages: 835-847

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591698
  • [Journal Article] T-cell factor-4-dependent up-regulation of fibronectin is involved in fibroblast growth factor-2-induced tube formation by endothelial cells.2005

    • Author(s)
      Shigeru Kanda, et al.
    • Journal Title

      Journal of Cellular Biochemistry 94(4)

      Pages: 835-847

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591686
  • [Journal Article] Pigment epithelium-derives factor inhibits fibroblast growth factor-2-induced capillary morphogenesis of endothehial cells through e-Fyn2005

    • Author(s)
      S.Kanda, Y.Moshizuki, T.Nakamura, Y.Miyata, T.Matsuyama, H.Kanetake
    • Journal Title

      Journal of Cell Science (In press)

    • Data Source
      KAKENHI-PROJECT-15591698
  • [Journal Article] Studies of the endothelial cell-specific signal transduction pathways. New paradigm for the development of potent anti-angiogenic therapies.2005

    • Author(s)
      Shigeru Kanda et al.
    • Journal Title

      Trends in Angiogenesis Research. (New York : Nova Science Publishers, Inc)

      Pages: 43-69

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591686
  • [Journal Article] Pigment epithelium-derived factor inhibits fibroblast growth factor-2-induced capillary morphogenesis of endothelial cells through c-Fyn.2005

    • Author(s)
      Shigeru Kanda, et al.
    • Journal Title

      Journal of Cell Science 118

      Pages: 961-970

    • Data Source
      KAKENHI-PROJECT-17591686
  • [Journal Article] T-cell factor-4-dependent up-regulation of fibronectin is involved in fibroblast growth factor-2-induced tube formation by endothelial cells.2005

    • Author(s)
      S.Kanda, Y.Mityata, H.Kanetake
    • Journal Title

      Journal of Cellular Biochemistry 94

      Pages: 835-847

    • Data Source
      KAKENHI-PROJECT-15591698
  • [Journal Article] Fibroblast growth factor-2-mediated capillary morphogenesis of endothelial cells requires signals via Fit-1/vascular endothelial growth factor receptor-1. Possible involvement of c-Akt.2004

    • Author(s)
      S.Kanda, Y.Miyata, H.Kanetake
    • Journal Title

      Journal of Biological Chemistry 279(6)

      Pages: 4007-4016

    • Data Source
      KAKENHI-PROJECT-15591698
  • [Journal Article] Role of focal adhesion formation in migration and morphogenesis of endothelial cells.2004

    • Author(s)
      Shigeru Kanda, Yasuyoshi Mityata, Hiroshi Kanetake
    • Journal Title

      Cellular Signaling 16

      Pages: 1273-1281

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591698
  • [Journal Article] Fibroblast growth factor-2-mediated capillary morphogenesis of endothelial cells requires signals via Flt-1/vascular endothelial growth factor receptor-1. Possible involvement of c-Akt.2004

    • Author(s)
      Shigeru Kanda, Yasuyoshi Miyata, Hiroshi Kanetake
    • Journal Title

      Journal of Biological Chemistry 279(6)

      Pages: 4007-4016

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591698
  • [Journal Article] Role of focal adhesion formation in migration and morphogenesis of endothelial cells.2004

    • Author(s)
      S.Kanda, Y.Miyata, H.Kanetake
    • Journal Title

      Cellular Signaling 16

      Pages: 1273-1281

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591698
  • [Journal Article] Fibroblast growth factor-2-mediated capillary morphogenesis of endothelial cells requires signals via Flt-1/vascular endothelial growth factor receptor-1. Possible involvement of c-Akt.2004

    • Author(s)
      S.Kanda, Y.Mityata, H.Kanetake
    • Journal Title

      Journal of Biological Chemistry 279(6)

      Pages: 4007-4016

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591698
  • [Journal Article] Role of focal adhesion formation in migration and morphogonesis of endothelial cells.2004

    • Author(s)
      S.Kanda, Y.Mityata, H.Kanetaka
    • Journal Title

      Cellular Signaling 16

      Pages: 1273-1281

    • Data Source
      KAKENHI-PROJECT-15591698
  • [Journal Article] Sonic hedgehog induces capillary morphogenesis by endothelial cells through phosphoinositide 3-kinase.2003

    • Author(s)
      Shigeru Kanda, Takashi Suematsu, Yasuyoshi Miyata, Yasushi Mochizuki, Koichiro Nomata, Hiroshi Kanetake
    • Journal Title

      Journal of Biological Chemistry 278(10)

      Pages: 8244-8249

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591698
  • [Journal Article] Sonic hedgehog induces capillary morphogenesis by endothelial cells through phosphoinositide2003

    • Author(s)
      S.Kanda, T.Suematsu, Y.Mityata, Y.Mochizuki, K.Nomata, H.Kanetake
    • Journal Title

      Journal of Biological Chemistry 278(10)

      Pages: 8244-8249

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591698
  • [Journal Article] Stromal cell-derived factor-1a induces tube-like structure formation of endothelial cells through phosphoinositide 3-kinase.2003

    • Author(s)
      S.Kanda, Y.Mochizuki, H.Kanetake
    • Journal Title

      Journal of Biological Chemistry 278(1)

      Pages: 257-262

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591698
  • [Journal Article] Stromal cell-derived factor-1a induces tube-like structure formation of endothelial cells through phosphoinositide 3-kinase.2003

    • Author(s)
      Shigeru Kanda, Yasushi Mochizuki, Hiroshi Kanetake
    • Journal Title

      Journal of Biological Chemistry 278(1)

      Pages: 257-262

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591698
  • [Journal Article] Studies of the endothelial cell-specific signal transduction pathways. New paradigm for the development of potent anti-angiogenic therapies.

    • Author(s)
      Shigeru Kanda, Yasuyoshi Miyata, Hiroshi Kanetake
    • Journal Title

      Progress in Angiogenesis Research(Nova Science Publishers, Inc.Hauppauge, NY, USA.) (In press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591698
  • 1.  KANETAKE hiroshi (50100839)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 18 results
  • 2.  NOMATA Koichiro (80189430)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  KOGA Shigehiko (10205354)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  OTSURU Akira (00233198)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  HAYASHI Toadyish (20253651)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  斉藤 泰 (70039832)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  井川 掌 (40295069)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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