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Yoshiko Yuji  吉子 裕二

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… Alternative Names

YOSHIKO Yuji  吉子 裕二

吉子 裕二  ヨシコ ユウジ

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Researcher Number 20263709
Other IDs
Affiliation (Current) 2022: 広島大学, 医系科学研究科(歯), 教授
Affiliation (based on the past Project Information) *help 2019 – 2021: 広島大学, 医系科学研究科(歯), 教授
2017 – 2018: 広島大学, 医歯薬保健学研究科(歯), 教授
2013 – 2016: 広島大学, 医歯薬保健学研究院(歯), 教授
2015: 広島大学, 大学院医歯薬保健学研究院, 教授
2013 – 2015: 広島大学, 医歯薬保健学研究院, 教授 … More
2012: 広島大学, 大学院・医歯薬保健学研究院, 教授
2012: 広島大学, 大学院医歯薬保健学研究院(歯), 教授
2011: 広島大学, 医歯(薬)学総合研究科, 准教授
2007 – 2010: Hiroshima University, Graduate School of Biomedical Sciences, Associate Professor
2006: HIROSHIMA UNIVERSITY, Graduate School of Biomedical Science, Associate Professor, 大学院医歯薬学総合研究科, 助教授
2004 – 2005: 広島大学, 大学院・医歯薬学総合研究科, 助教授
2002: 広島大学, 大学院医歯薬学総合研究科, 助手
2001: 広島大学, 歯学部, 助手
1997 – 1999: 広島大学, 歯学部, 助手
1996: 広島大学, 医学部, 助手
1995: 広島大学, 歯学部, 助手 Less
Review Section/Research Field
Principal Investigator
Morphological basic dentistry / Morphological basic dentistry / Medium-sized Section 57:Oral science and related fields
Except Principal Investigator
Morphological basic dentistry / Morphological basic dentistry / Basic Section 57010:Oral biological science-related / Surgical dentistry / Dental engineering/Regenerative dentistry / Basic Section 56020:Orthopedics-related / Basic Section 57070:Developmental dentistry-related
Keywords
Principal Investigator
骨芽細胞 / FGF23 / 石灰化 / Pit1 / 骨軟化症 / くる病 / Klotho / マウス / KLotho / Phex … More / 骨細胞 / 骨形成 / 筋芽細胞 / 分化 / インスリン様成長因子 / 性ホルモン / NaPi運搬体 / 細胞分化 / NaPi輸送担体 / GF23 / マップキナーゼ(ERK) / 可溶型Klotho / 可溶化Klotho(細胞外ドメイン) / 歯・骨の石灰化 / ERK / ASARM / 骨代謝 / ビタミンD / 無機リン酸(Pi) / スタニオカルシン1 / 軟骨細胞 / 軟骨 / スタニオカルシン / リン酸 / 骨軟化症・くる病 / NaPiトランスポーター / アデノウイルス / 培養 / osteobast / inorganic phosphate / stanniocalcin 1 / ricket / osteomalacia / chondrocyte / 骨の石灰化 / リン酸代謝調節因子 / NaPiコトランスポーター / Pitl / 歯の形成 / くる病・骨軟化症 / 低リン血症 / 無機リン酸 / マイクロアレイ / Bone mineralization / Osteoblasts / Phosphaturic factor / NaPi cotransporter / Pit 1 / 多様性 / 運命決定 / シングルセルRNA-Seq / 非翻訳RNA / 最終分化 / Cd34 / ncRNA / lining cell / シングルセル RNA-Seq / シングルセル 解析 / 細胞運命決定 … More
Except Principal Investigator
骨代謝 / 骨芽細胞 / 細胞・組織 / 骨転移 / エストロゲン / リン代謝 / FGF23 / Tie2 / Angiopoietin / Haemangioma / Fibrous growth factor 23 / Angiosarcoma / miRNA / マウス / 骨格筋 / 咬筋 / エストロゲン受容体 / 加齢 / 咀嚼筋 / 免疫組織化学 / PTH / Klotho / がん細胞 / エピジェネティクス / Bone lining cells / 骨形成 / 咀嚼器官 / 三叉神経運動核 / 発達 / 老化 / 性ホルモンの効果 / 性ホルモンレセプター / 咀嚼システム / 発達と性差 / 男性ホルモン / 女性ホルモン / ニューロン数 / 発達と老化 / 歯根膜 / 抜歯 / 末梢性入力減少 / 運動神経細胞数減少 / 性ホルモン / Masticatory Organ / Trigeminal motor nucleus / Development / Aging / Sex hormone effects / Sex hormone receptors / Angiosaicoma / Hemangioma / 破骨細胞 / 骨髄骨 / 骨吸収 / 単一細胞解析 / 発生・分化 / 骨・軟骨再生 / 線維芽細胞増殖因子 / 骨軟骨再生 / 線維芽細胞増殖因子10 / 再生歯学 / 再生医学 / miR-125b / 基質小胞 / 血管異所性石灰化 / 血管平滑筋 / RNAシーケンシング / イノシトールリン酸 / 異所性石灰化 / 次世代シークエンシング / 歯科矯正学 / 再生医療 / エクソソーム Less
  • Research Projects

    (21 results)
  • Research Products

    (120 results)
  • Co-Researchers

    (30 People)
  •  一細胞遺伝子発現プロファイルに基づく骨芽細胞系譜の分化多様性機構の解明

    • Principal Investigator
      吉岡 広陽
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      International University of Health and Welfare
  •  クロマチンと遺伝子発現の網羅的解析の併用による組織特異的石灰化機序の同定

    • Principal Investigator
      河野 尚平
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57010:Oral biological science-related
    • Research Institution
      Hiroshima University
  •  乳歯歯髄幹細胞由来エクソソームの機能解析と顎裂部骨再生誘導への応用

    • Principal Investigator
      谷本 幸太郎
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57070:Developmental dentistry-related
    • Research Institution
      Hiroshima University
  •  miR-125bを導入した基質小胞による癌骨転移治療の検討

    • Principal Investigator
      南崎 朋子
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57010:Oral biological science-related
    • Research Institution
      Hiroshima University
  •  Elucidation of osteoblast fate determination by single cell analysis on mRNA-ncRNAPrincipal Investigator

    • Principal Investigator
      Yoshiko Yuji
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 57:Oral science and related fields
    • Research Institution
      Hiroshima University
  •  Elucidation of the mechanism of osteoblast fate regulation by single cell analysis and search for target molecules of novel osteogenesis-promoting agents

    • Principal Investigator
      Yoshioka Hirotaka
    • Project Period (FY)
      2017 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      International University of Health and Welfare
  •  Functional analysis of a novel soluble FGF receptor from bone and cartilage and application to osteochondral regeneration

    • Principal Investigator
      Kagawa Kazuko
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dental engineering/Regenerative dentistry
    • Research Institution
      Hiroshima University
  •  A trial of miRNAs derived from bone matrix as an inhibitor for bone metastasis

    • Principal Investigator
      Minamizaki Tomoko
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Hiroshima University
  •  The mechanism of regulation by estrogen and estrogen target factors to osteoclastic apoptosis and bone resorption

    • Principal Investigator
      Hiyama Shinji
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Hiroshima University
  •  Development of bone regeneration strategies by controlling the epigenetic state of bone lining cells.

    • Principal Investigator
      YOSHIOKA HIROTAKA
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Hiroshima University
  •  The roles of downstream factor(s) of cancer cell-derived Klotho on bone mineralization

    • Principal Investigator
      MINAMIZAKI TOMOKO
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Hiroshima University
  •  Study of the FGF23-soluble Klotho axis in bone and dental diseases.Principal Investigator

    • Principal Investigator
      YOSHIKO YUJI
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Hiroshima University
  •  A basic study of de novo function of PTH in mineral metabolism disorders

    • Principal Investigator
      MINAMIZAKI Tomoko
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Hiroshima University
  •  A basic study on FGF23 for molecular targeted therapy of bone/tooth diseasesPrincipal Investigator

    • Principal Investigator
      YOSHIKO Yuji
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Hiroshima University
  •  Basic research for phosphaturic factors including FGF23 as molecular targets for clinical applications.Principal Investigator

    • Principal Investigator
      YOSHIKO Yuji
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Hiroshima University
  •  Association of aberrant receptor tyrosine kinase signaling pathways in malignant transformation of endothelial cells

    • Principal Investigator
      WANG Hua
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Surgical dentistry
    • Research Institution
      HIROSHIMA UNIVERSITY
  •  Basic studies of a gene therapy approach for osteoblastic (odontoblastic) disability in inherited and tumor-induced hypophosphatemic disordersPrincipal Investigator

    • Principal Investigator
      YOSHIKO Yuji
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      HIROSHIMA UNIVERSITY
  •  象牙質形成/骨形成異常と象牙芽細胞/骨芽細胞のリン酸代謝との関係 -とくにX連鎖性低リン酸性ビタミンD抵抗性くる病の原因遺伝子PHEXとナトリウム/リン酸共運搬体によるリン酸代謝について-Principal Investigator

    • Principal Investigator
      吉子 裕二
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Hiroshima University
  •  study on the development, aging and the regulation factors of the maintenance of the masticatory organs

    • Principal Investigator
      MAEDA Norihiko
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Hiroshima University
  •  エストロゲンによる骨格筋の老化予防に関する研究

    • Principal Investigator
      MAEDA Norihiko
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Hiroshima University
  •  阻嚼筋の細胞分化・成長におけるエストロゲンおよびアンドロゲンの作用Principal Investigator

    • Principal Investigator
      吉子 裕二
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Hiroshima University

All 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation Patent

  • [Journal Article] Single‐Cell RNA‐Sequencing Reveals the Breadth of Osteoblast Heterogeneity2021

    • Author(s)
      Yoshioka H, Okita S, Nakano M, Minamizaki T, Nubukiyo A, Sotomaru Y, Bonnelye E, Kozai K, Tanimoto K, Aubin JE, Yoshiko Y
    • Journal Title

      JBMR Plus

      Volume: -

    • DOI

      10.1002/jbm4.10496

    • NAID

      120007183697

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11613, KAKENHI-PROJECT-18K19647, KAKENHI-PROJECT-18K17258, KAKENHI-PROJECT-19H01056, KAKENHI-PROJECT-21K09331
  • [Journal Article] The matrix vesicle cargo miR-125b accumulates in the bone matrix, inhibiting bone resorption in mice2020

    • Author(s)
      Minamizaki T, Nakao Y, Irie Y, Ahmed F, Itoh S, Sarmin N, Yoshioka H, Nobukiyo A, Fujimoto C, Niida S, Sotomaru Y, Tanimoto K, Kozai K, Sugiyama T, Bonnelye E, Takei Y, Yoshiko Y
    • Journal Title

      Communications Biology

      Volume: 3 Pages: 30-30

    • DOI

      10.1038/s42003-020-0754-2

    • NAID

      120006824053

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11613, KAKENHI-PROJECT-19K19268
  • [Journal Article] Active sites of human MEPE-ASARM regulating bone matrix mineralization2020

    • Author(s)
      Minamizaki T, Sakurai K, Hayashi I, Toshishige M, Yoshioka H, Kozai K, Yoshiko Y
    • Journal Title

      Molecular and Cellular Endocrinology

      Volume: 517 Pages: 110931-110931

    • DOI

      10.1016/j.mce.2020.110931

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K11613
  • [Journal Article] Soluble Klotho causes hypomineralization in Klotho-deficient mice2018

    • Author(s)
      Minamizaki T, Konishi Y, Sakurai K, Yoshioka H, Aubin JE, Kozai K, Yoshiko Y
    • Journal Title

      Journal of Endocrinology

      Volume: 237 Pages: 285-300

    • DOI

      10.1530/joe-17-0683

    • NAID

      120006826841

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K11613
  • [Journal Article] Comparative proteome analysis of wild-type and klotho-knockout mouse kidneys using a combination of MALDI-IMS and LC-MS/MS.2017

    • Author(s)
      Fujino Y, Minamizaki T, Hayashi I, Kawakami A, Miyaji T, Sakurai K, Yoshioka H, Kozai K, Okada M, Yoshiko Y.
    • Journal Title

      Proteomics Clinical Applications

      Volume: 8 Pages: 7-8

    • DOI

      10.1002/prca.201600095

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26460067, KAKENHI-PROJECT-26462785, KAKENHI-PROJECT-17K19489
  • [Journal Article] Imaging and mapping of mouse bone using MALDI-imaging mass spectrometry.2016

    • Author(s)
      Fujino Y, Minamizaki T, Yoshioka H, Okada M, Yoshiko Y
    • Journal Title

      Bone Reports

      Volume: 5 Pages: 280-285

    • DOI

      10.1016/j.bonr.2016.09.004

    • NAID

      120006824051

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26462785
  • [Journal Article] The dynamics of DNA methylation and hydroxymethylation during amelogenesis.2015

    • Author(s)
      Yoshioka H, Minamizaki T, Yoshiko Y.
    • Journal Title

      Histochemistry and Cell Biology

      Volume: 144 Pages: 471-478

    • DOI

      10.1007/s00418-015-1353-z

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26462785
  • [Journal Article] The bioactive acidic serine- and aspartate-rich motif peptide.2015

    • Author(s)
      Minamizaki T, Yoshiko Y.
    • Journal Title

      Current Protein & Peptide Science

      Volume: 16 Pages: 196-202

    • DOI

      10.2174/1389203716666150206122839

    • NAID

      120006879596

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25462858
  • [Journal Article] Functional Diversity of Fibroblast Growth Factors in Bone Formation.2015

    • Author(s)
      Takei Y, Minamizaki T, Yoshiko Y.
    • Journal Title

      International journal of endocrinology

      Volume: 2015 Pages: 729352-729352

    • DOI

      10.1155/2015/729352

    • NAID

      120006824054

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25462858, KAKENHI-PROJECT-26861548
  • [Journal Article] 骨・血管相関とmicro RNA2014

    • Author(s)
      竹井悠一郎,吉子裕二
    • Journal Title

      臨床化学

      Volume: 43 Pages: 106-111

    • Data Source
      KAKENHI-PROJECT-23592701
  • [Journal Article] one of the major anthocyanidins, prevents bone loss through the inhibition of excessive osteoclastogenesis in osteoporpsis model mice2014

    • Author(s)
      Moriwaki Sawako, Suzuki Keiko, Muramatsu Masashi, Nomura Atsushi, Inoue Fuihide, Into Takeshi, Yoshiko Yuji, Niida Shumpei,Delphinidin
    • Journal Title

      PLoS One

      Volume: 9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592701
  • [Journal Article] The EP4-ERK-dependent pathway stimulates osteo-adipogenic progenitor proliferation resulting in increased adipogenesis in fetal rat calvaria cell cultures.2012

    • Author(s)
      Minamizaki Tomoko, Yoshiko Yuji, Yoshioka Hirotaka, KOzai Katsuyuki, Aubin Jane E, Maeda Norihiko
    • Journal Title

      Prostaglandins Other Lipid Mediat.

      Volume: 97 Pages: 97-102

    • DOI

      10.1016/j.prostaglandins.2012.01.001

    • NAID

      120006879597

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592701, KAKENHI-PROJECT-23792105
  • [Journal Article] Incisor enamel formation is impaired in transgenic rats overexpressing the type III NaPi transporter Slc20a12012

    • Author(s)
      Yoshioka Hirotaka, Yoshiko Yuji, Minamizaki Tomoko, Suzuki Sayaka, Koma Yoshiro, Nobukiyo Asako, Sotomaru Yusuke, Suzuki Atsushi, Ito Mitsuyasu, Maeda Norihiko
    • Journal Title

      Calcif Tissue Int

      Volume: 89 Pages: 192-202

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23792105
  • [Journal Article] The EP4-ERK-dependent pathway stimulates osteo-adipogenic progenitor proliferation resulting in increased adipogenesis in fetal rat calvaria cell cultures2012

    • Author(s)
      Minamizaki Tomoko, Yoshiko Yuji, Yoshioka Hirotaka, Kozai Katsuyuki, Jane E Aubin, Maeda Norihiko
    • Journal Title

      Prostaglandins Other Lipid Mediat

      Volume: 97 Pages: 97-102

    • NAID

      120006879597

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23792105
  • [Journal Article] Incisor snemal formation is impaired in transgenic rats overexpressing the type III NaPi transporter Slc20a12012

    • Author(s)
      Hirotaka Yoshioka, Yuji Yoshiko, Tomoko Minamizaki, Sayaka Suzuki, Yoshiro Koma, Asako Nobukiyo, Yusuke Sotomaru, Atsushi Suzuki, Mitsuyasu Itoh, Norihiko Maeda
    • Journal Title

      Calcif Tissue Int.

      Volume: 89 Pages: 192-202

    • DOI

      10.1007/s00223-011-9506-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22791768, KAKENHI-PROJECT-23592701, KAKENHI-PROJECT-23792105
  • [Journal Article] Ameloblastin regulates osteogenic differentiation by inhibitig Src kinase via cross talk between integrin b1 and CD63.2011

    • Author(s)
      Iizuka S, Kudo Y, Yoshida M, Tsunematsu T, Yoshiko Y, et al.
    • Journal Title

      Mol Cell Biol 32(4)

      Pages: 783-792

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592139
  • [Journal Article] Incisor enamel formation is impaired in transgenic rats overexpressing the type III NaPi transporter Slc20a1.2011

    • Author(s)
      Yoshioka H, Yoshiko Y, Minamizaki T, Suzuki S, Koma Y, Nobukiyo A, Sotomaru Y, Suzuki A, Itho M, Maeda N.
    • Journal Title

      Calcified Tissue International

      Volume: 89 Pages: 192-202

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592701
  • [Journal Article] 1・,25-dihydroxy-vitamin D3 acts predominately in mature osteoblasts under conditions of high extracellular phosphate to increase fibroblast growth factor 23 production in vitro.2010

    • Author(s)
      Yamamoto R, Minamizaki T, Yoshiko Y, Yoshioka H, et al.
    • Journal Title

      J Endocrinol 206(3)

      Pages: 279-286

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592139
  • [Journal Article] A subset of osteoblasts expressing high endogenous levels of PPARγ switches fate to adipocytes in the rat calvaria cell culture model.2010

    • Author(s)
      Yoshiko Y, Oizumi K, Hasegawa T, Minamizaki T, et al.
    • Journal Title

      PLoS One 26 5(7)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592139
  • [Journal Article] A subset of osteoblasts expressing high endogenous levels of PPARγ switches fate to adipocytes in the rat calvaria cell culture model.2010

    • Author(s)
      Yoshiko Y, 他
    • Journal Title

      PLoS One

      Volume: 26

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592139
  • [Journal Article] 低リン血症にみる歯の形成の分子基盤2009

    • Author(s)
      吉子裕二
    • Journal Title

      広島県歯科医学雑誌 (印刷中)

    • Data Source
      KAKENHI-PROJECT-20592139
  • [Journal Article] EP2 and EP4 receptors differentially mediate MAPK pathways underlying anabolic actions of prostaglandin E2 on bone formation in rat calvaria cell cultures.2009

    • Author(s)
      Minamizaki T, Yoshiko Y, Kozai K, Aubin JE, Maeda N
    • Journal Title

      Bone 44(6)

      Pages: 1177-1185

    • NAID

      120001924001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592139
  • [Journal Article] 低リン血症にみる歯の形成の分子基盤2008

    • Author(s)
      吉子裕二, 南崎朋子, 吉岡広陽, 鈴木清香, 前田憲彦
    • Journal Title

      広島歯誌 36

      Pages: 1-12

    • Data Source
      KAKENHI-PROJECT-20592139
  • [Journal Article] New insights into the roles of 丘broblast growth factor 23.2008

    • Author(s)
      Yuji Yoshiko
    • Journal Title

      Clinical Review of Bone and Mineral Metabolism 6

      Pages: 17-23

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592139
  • [Journal Article] New Insights into the Roles of Fibroblast Growth Factor 23.2008

    • Author(s)
      Yoshiko Y, Minamizaki T, Maeda N
    • Journal Title

      Clinzc Rev Bone Miner Metab 6

      Pages: 17-23

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20592139
  • [Journal Article] Mineralized tissue cells are a principal source of FGF23.2007

    • Author(s)
      Yoshiko Y., Wang H., et al.
    • Journal Title

      Bone (Epub ahead of print)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17592086
  • [Journal Article] Mineralized tissue cells are a principal source of FGF23.2007

    • Author(s)
      Yoshiko Y., Wang H., Minamizaki T., Ijuin C., Yamamoto R, Suemune S., Kozai K., Tanne K., Aunin J.E., Maeda N.
    • Journal Title

      Bone (In press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17592086
  • [Journal Article] Osteoblast autonomous Pi regulation via Pit 1 plays a role in Bone formation2007

    • Author(s)
      Yuji, Yoshiko
    • Journal Title

      Mol Cell Biol 27

      Pages: 4465-4474

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592001
  • [Journal Article] Mineralized tissue cells are a principle source of FGF232007

    • Author(s)
      Yuji, Yoshiko
    • Journal Title

      Bone 40

      Pages: 1565-1573

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592001
  • [Journal Article] Osteoblast autonomous Pi regulation via Pit1 plays a role in bone formation.2007

    • Author(s)
      Yuji Yoshiko
    • Journal Title

      Mol Cell Biol 27

      Pages: 4465-4474

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18592001
  • [Journal Article] Mineralized tissue cells are a principal source of FGF23.2007

    • Author(s)
      Yuji Yoshiko
    • Journal Title

      Bone 40

      Pages: 1565-1573

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18592001
  • [Journal Article] Mineralized tissue cells are a principal source of FG23.2007

    • Author(s)
      Yuji Yoshiko
    • Journal Title

      Bone (Epub adead of print)

    • Data Source
      KAKENHI-PROJECT-18592001
  • [Journal Article] Mineralized tissue cells are a principal source of FGF23.2007

    • Author(s)
      Yoshiko Y., Wang H., et al.
    • Journal Title

      Bone (掲載決定)

    • Data Source
      KAKENHI-PROJECT-17592086
  • [Journal Article] Osteoblast autonomous Pi regulation via Pit1 plays a role in bone mineralization.2007

    • Author(s)
      Yoshiko, Y.
    • Journal Title

      Mol. Cell. Biol. 27-12

      Pages: 4465-4474

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18592001
  • [Journal Article] FGF23 acts as an autocrine/paracrine negative regulator for osteoblast development and matrix mineralization in fetal rat calvaria cell cultures.2006

    • Author(s)
      Wang H., Yamamoto R., Minamizaki T., Suemune S., Kozai K., Tanne K., Aunin J.E., Maeda N., Yoshiko Y.
    • Journal Title

      J Bone Miner.Res. 21

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17592086
  • [Journal Article] Remedies for mineralization regulation.2006

    • Author(s)
      Yoshiko Y., Wang H., Maeda N., Yamamoto R, Minamizaki T., Yoshida B.
    • Journal Title

      Patent : Japan 2006

      Pages: 194078-194078

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17592086
  • [Journal Article] Adenovirus-mediated overexpression, of FGF23 suppresses osteoblast development and matrix mineralization in fetal rat calvaria cell.2005

    • Author(s)
      Wang H., Yamamoto R., Minamizaki T., Suemune S., Kozai K., Tanne K., Aunin J.E., Maeda N., Yoshiko Y.
    • Journal Title

      J.Bone Miner.Res. 20

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17592086
  • [Patent] リン酸化ペプチド、硬組織および/または異所性石灰化抑制剤、抗体ならびに硬組織および/または異所性石灰化促進剤2012

    • Inventor(s)
      吉子裕二、南崎朋子他
    • Industrial Property Rights Holder
      広島大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2012-07-06
    • Overseas
    • Data Source
      KAKENHI-PROJECT-23592701
  • [Patent] リン酸化ペプチド、硬組織および/または異所性石灰化抑制剤、抗体ならびに硬組織および/または異所性石灰化促進剤2011

    • Inventor(s)
      吉子裕二, 南崎朋子, 吉岡広陽, 平田伊佐雄, 香西克之, 前田憲彦, 渡邉和晃, 清藤勉
    • Industrial Property Rights Holder
      国立大学法人広島大学, 株式会社ラフィーネインターナショナル, 株式会社免疫生物研究所
    • Industrial Property Number
      2011-150487
    • Filing Date
      2011-07-06
    • Data Source
      KAKENHI-PROJECT-23792105
  • [Patent] 石灰化組織における可溶化Klotho,FGF23およびFGF23複合体形成機構を利用した用途2011

    • Inventor(s)
      吉子裕二,南崎朋子他
    • Industrial Property Rights Holder
      広島大学
    • Filing Date
      2011
    • Overseas
    • Data Source
      KAKENHI-PROJECT-23592701
  • [Patent] リン酸化ペプチド、硬組織および/または異所性石灰化抑制剤,抗体ならびに硬組織および/または異所性石灰化促進剤2011

    • Inventor(s)
      吉子裕二,南崎朋子他
    • Industrial Property Rights Holder
      広島大学他
    • Industrial Property Number
      2011-150487
    • Filing Date
      2011
    • Data Source
      KAKENHI-PROJECT-23592701
  • [Patent] リン酸化ペプチド、硬組織および/または異所性石灰化抑制剤,抗体ならびに硬組織および/または異所性石灰化促進剤2011

    • Inventor(s)
      吉子裕二,南崎朋子,吉岡広陽,平田伊佐雄,香西克之,前田憲彦,渡邊和晃,清藤勉
    • Industrial Property Rights Holder
      広島大学,(株)ラフィーネインターナショナル,(株)免疫生物研究所種類
    • Industrial Property Rights Type
      特許
    • Filing Date
      2011-07-06
    • Overseas
    • Data Source
      KAKENHI-PROJECT-23592701
  • [Patent] 石灰化組織における可溶化Klotho、FGF23およびFGFR複合体形成機構を利用した用途2011

    • Inventor(s)
      吉子裕二, 南崎朋子, 吉岡広陽, 前田憲彦, 香西克之, 渡邉和晃
    • Industrial Property Rights Holder
      国立大学法人広島大学, 株式会社ラフィーネインターナショナル
    • Industrial Property Number
      2011-123853
    • Filing Date
      2011-06-01
    • Data Source
      KAKENHI-PROJECT-23792105
  • [Patent] 石灰化組織における可溶化Klotho、 FGF 23およびFGFR複合体形成機構を利用した用途2010

    • Inventor(s)
      吉子裕二, 他
    • Industrial Property Rights Holder
      広島大学、ラフィーネインターナショナル
    • Industrial Property Number
      2010-136637
    • Filing Date
      2010-06-15
    • Data Source
      KAKENHI-PROJECT-20592139
  • [Patent] 石灰化組織における可溶化Klotho、FGF23およびFGFR複合体形成機構を利用した用途2010

    • Inventor(s)
      吉子裕二, 南崎朋子, 吉岡広陽, 他
    • Industrial Property Rights Holder
      広島大学,ラフィーネインターナショナル
    • Industrial Property Number
      2010-136637
    • Filing Date
      2010-06-15
    • Data Source
      KAKENHI-PROJECT-20592139
  • [Patent] 石灰化調節剤およびそのスクリーニング法2006

    • Inventor(s)
      吉子裕二, 汪 華, 前田憲彦
    • Industrial Property Rights Holder
      広島大学
    • Industrial Property Number
      2006-194078
    • Filing Date
      2006-07-14
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17592086
  • [Presentation] 4:Calciprotein particles play a role in bone formation and vascular calcification2021

    • Author(s)
      Davood Kharaghani, Eben Bashir Kurniawan, Shohei Kohno, Tomonori Hoshino, Tomoko Minamizaki, Yuji Yoshiko
    • Organizer
      6th Joint Scientific Meeting in Dentistry
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K09816
  • [Presentation] 6:MEPE-derived ASARM, an inhibitor of calciparticle protein formation, suppresses vascular calcification but not bone formation2021

    • Author(s)
      Davood Kharaghani, Tomoko Minamizaki, Shohei Kohno, Tomonori Hoshino, Yuji Yoshiko
    • Organizer
      ASBMR 2021 Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K09816
  • [Presentation] A new paradigm for bone turnover and its potential clinical implications2019

    • Author(s)
      Yuji Yoshiko
    • Organizer
      International Dental Scientific Conference and Expo, Dies Forum 2019
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19647
  • [Presentation] シングルセル解析から見た骨芽細胞の多様性と脂肪細胞分化転換能2019

    • Author(s)
      中野将志,吉岡広陽,南崎朋子,香西克之,吉子裕二
    • Organizer
      第124回日本解剖学会総会・全国学術集会
    • Data Source
      KAKENHI-PROJECT-18K19647
  • [Presentation] A synthetic peptide derived from the SIBLING protein MEPE inhibits ectopic mineralization but not bone formation.2019

    • Author(s)
      Minamizaki T, Toshishige M, Yoshioka H, Ahmed F, Mine Y, Yoshiko Y
    • Organizer
      World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11613
  • [Presentation] シングルセル解析から見た骨芽細胞の多様性と脂肪細胞分化転換能2019

    • Author(s)
      中野将志,吉岡広陽,南崎朋子,香西克之,吉子裕二
    • Organizer
      第124回日本解剖学会総会・全国学術集会
    • Data Source
      KAKENHI-PROJECT-17K11613
  • [Presentation] Plasticity of osteoblasts and their adipogenic potential dissected by single cell RNA-sequencing.2019

    • Author(s)
      Yoshioka H, Nakano M, Minamizaki T, Kozai K, Yoshiko Y
    • Organizer
      The American Society of Bone and Mineral Research 2019 Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11613
  • [Presentation] MiR-125b stored in bone matrix plays a role in osteoblast-osteoclast communication.2018

    • Author(s)
      Tomoko Minamizaki, Yuji Yoshiko
    • Organizer
      The 10th Annual Meeting of the Japanese Association for RNAi (JARI) The 5th Annual Meeting of Japanese Society of Extracellular Vesicles (JSEV)
    • Data Source
      KAKENHI-PROJECT-16K11443
  • [Presentation] Single-cell RNA sequencing provides molecular dissection of osteoblasts and their adipogenic potential.2017

    • Author(s)
      Nakano M, Yoshioka H, Okita S, Tanimoto K, Kozai K, Minamizaki T, Yoshiko Y
    • Organizer
      2017 Annual meeting of the American Society for Bone and Mineral Research.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11613
  • [Presentation] Single-cell RNA-sequencing shows the adipogenic potential in osteoblasts.2017

    • Author(s)
      Okita S, Yoshioka H, Minamizaki T, Tanimoto K, Yoshiko Y
    • Organizer
      2017 ANZBMS-IFMRS Joint Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11613
  • [Presentation] シングルセルRNA-seqによる骨芽細胞の多様性と脂肪細胞分化能の解析2017

    • Author(s)
      沖田紗季,吉岡広陽,南崎朋子,吉子裕二
    • Organizer
      第35回日本骨代謝学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K11613
  • [Presentation] Osteoblasts inhibit osteoclast formation by targeting Prdm1 via the mechanism underlying matrix vesicle-mediated transfer of miR-125b.2016

    • Author(s)
      Irie Y, Minamizaki T, Ahmed F, Nakao Y, Yoshioka H, Tanimoto K, Kozai K, Yoshiko Y
    • Organizer
      The American Society of Bone and Mineral Research 2016 Annual Meeting
    • Place of Presentation
      Atlanta, GA, USA
    • Year and Date
      2016-09-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462785
  • [Presentation] Histomorphometric analysis of Klotho-deficient mice by nano-CT.2016

    • Author(s)
      Ahmed F,Minamizaki T,Yoshioka H,Yoshiko Y
    • Organizer
      日本解剖学会第71回中国・四国支部学術集会
    • Place of Presentation
      岡山
    • Year and Date
      2016-10-22
    • Data Source
      KAKENHI-PROJECT-26462785
  • [Presentation] 骨芽細胞は基質小胞を介してmiR-125bを輸送し,Prdm1を標的として破骨細胞の形成を抑制する2016

    • Author(s)
      入江泰正,南崎朋子,中尾裕子,Faisal Ahmed,吉岡広陽,香西克之,竹井悠一郎,吉子裕二
    • Organizer
      第34回日本骨代謝学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2016-07-20
    • Data Source
      KAKENHI-PROJECT-26462785
  • [Presentation] MicroRNA-125b in bone matrix plays a crucial role in osteoblast-osteoclast communication.2016

    • Author(s)
      Minamizaki T, Takei Y, Nakao Y, Irie Y, Yoshioka H, Tanimoto K, Kozai K, Yoshiko Y
    • Organizer
      43rd Annual European Calcified Tissue Society Congress
    • Place of Presentation
      Rome, Italy
    • Year and Date
      2016-05-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462785
  • [Presentation] Matrix vesicle miR-125b suppress osteoclast formation by targeting Prdm1.2016

    • Author(s)
      Irie Y, Minamizaki T, Nakao Y, Ahmed F, Yoshioka H, Kozai K, Tanimoto K, Yoshiko Y
    • Organizer
      Annual Meetings of the Endocrine Society of Australia and Society for Reproductive Biology and Australia and New Zealand Bone and Mineral Society 2016
    • Place of Presentation
      Queensland, Australia
    • Year and Date
      2016-08-21
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462785
  • [Presentation] シングルセルRNA-seqによる骨芽細胞の多様性の解析2016

    • Author(s)
      沖田紗季,吉岡広陽,南崎朋子,谷本幸太郎,吉子裕二
    • Organizer
      日本解剖学会第71回中国・四国支部学術集会
    • Place of Presentation
      岡山
    • Year and Date
      2016-10-22
    • Data Source
      KAKENHI-PROJECT-26462785
  • [Presentation] 骨芽細胞の多様性と脂肪細胞への分化転換2016

    • Author(s)
      沖田紗季,吉岡広陽,南崎朋子,谷本幸太郎,吉子裕二
    • Organizer
      第39回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2016-11-30
    • Data Source
      KAKENHI-PROJECT-26462785
  • [Presentation] Matrix Vesicles Mediate the Cell-to-Cell Transmission of MicroRNA-125b as an Inhibitor of Osteoclastic Bone Resorption.2015

    • Author(s)
      Takei Y, Nakao Y, Minamizaki T, Irie Y, Ahmed F, Yoshioka H, Niida S, Tanimoto K, Yoshiko Y
    • Organizer
      The American Society for Bone and Mineral Research 2015 Annual Meeting
    • Place of Presentation
      Seattle, USA
    • Year and Date
      2015-10-09
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462785
  • [Presentation] A Novel isoform of FGFR2 Modulates FGF10-FGFR Signaling in Osteochondrogenesis.2015

    • Author(s)
      Yoshioka H, Kagawa K, Okita S, Kuremoto K, Takei Y, Minamizaki T, Tanimoto K, Tsuga K, Yoshiko Y
    • Organizer
      6th Hiroshima Conference on Education and Science in Dentistry
    • Place of Presentation
      広島国際会議場
    • Year and Date
      2015-10-23
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462785
  • [Presentation] Bone-derived miRNA as a mediator of cell-cell communication.2015

    • Author(s)
      Takei Y, Minamizaki T, Yoshioka H, Yoshiko Y
    • Organizer
      6th Hiroshima Conference on Education and Science in Dentistry
    • Place of Presentation
      広島国際会議場
    • Year and Date
      2015-10-23
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462785
  • [Presentation] Nano-CT Analysis of Osteocyte Anomalies in Klotho-deficient Mice.2015

    • Author(s)
      Minamizaki T, Sakurai K, Yoshioka H, Takei Y, Kozai K, Yoshiko Y
    • Organizer
      The American Society for Bone and Mineral Research 2015 Annual Meeting
    • Place of Presentation
      Seattle, USA
    • Year and Date
      2015-10-09
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25462858
  • [Presentation] MEPE-ASARM, a substrate of the neutral endopeptidase PHEX involved in rickets/osteomalacia, acts as an inhibitor of bone formation.2015

    • Author(s)
      Sakurai K, Minamizaki T, Hayashi I, Yoshioka H, Takei Y, Kozai K, Yoshiko Y
    • Organizer
      6th Hiroshima Conference on Education and Science in Dentistry
    • Place of Presentation
      Hiroshima
    • Year and Date
      2015-10-23
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25462858
  • [Presentation] Newly Identified FGFR2 Isoform Modulates FGF10-FGFR Signaling During Osteochondrogenesis.2015

    • Author(s)
      Kagawa K, Yoshioka H, Okita S, Kuremoto K, Takei Y, Minamizaki T, Tanimoto K, Tsuga K, Yoshiko Y
    • Organizer
      The American Society for Bone and Mineral Research 2015 Annual Meeting
    • Place of Presentation
      Seattle, USA
    • Year and Date
      2015-10-09
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462785
  • [Presentation] MicroRNAs Involved in Bone Metabolism Are Transported into Matrix Vesicles during Bone Formation.2015

    • Author(s)
      Nakao Y, Takei Y, Minamizaki T, Yoshioka H, Ahmed F, Tanimoto K, Niida S, Yoshiko Y
    • Organizer
      The American Society for Bone and Mineral Research 2015 Annual Meeting
    • Place of Presentation
      Seattle, USA
    • Year and Date
      2015-10-09
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462785
  • [Presentation] MEPE=ASARM, a substrate of Phex, decreases bone volume independently ofserum phosphate levels.2014

    • Author(s)
      Sakurai K, Minamizaki T, Fujino Y, Takei Y, Yoshioka H, Okada M, Kozai K, Yoshiko Y
    • Organizer
      The American Society for Bone and Mineral Research 2014 Annual Meeting
    • Place of Presentation
      Houston, TX, USA
    • Data Source
      KAKENHI-PROJECT-25462858
  • [Presentation] Phexの基質MEPE-ASARMは血中リン濃度非依存的に骨量を減少させる2014

    • Author(s)
      櫻井薫,南崎朋子,吉岡広陽,竹井悠一郎,香西克之,吉子裕二
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-23592701
  • [Presentation] MEPE-ASARM, a substrate of Phex, decreases bone volume independently of serum phosphate levels.2014

    • Author(s)
      Sakurai K, Minamizaki T, Fujino, Takei Y, Yoshioka H, Okada M, Kozai K, Yoshiko Y
    • Organizer
      The American Society for Bone and Mineral Research 2014 Annual Meeting
    • Place of Presentation
      Houston, TX, USA
    • Data Source
      KAKENHI-PROJECT-23592701
  • [Presentation] MEPE-ASARM, a substrate of Phex, decreases bone volume independently of serum phosphate levels2014

    • Author(s)
      Sakurai Kaoru,Minamizaki Tomoko, Fujino Yoko, Takei Yuichiro, Yoshioka Hirotaka, Okada Mitsugu, Kozai Katsuyuki, Yoshiko Yuji
    • Organizer
      The American Society for Bone Mineral Research 2014 Annual Meeting
    • Place of Presentation
      Houston, USA
    • Data Source
      KAKENHI-PROJECT-23592701
  • [Presentation] Imaging mass spectrometry-based molecular histology of bone shows the Implication of MEPE-ASARM for the Klotho-deficient phenotype.2013

    • Author(s)
      Fujino Y, Minamizaki T, Sakurai K, Irie Y, Yoshioka H, Takei Y, Kozai K, Okada M, Yoshiko Y
    • Organizer
      The American Society for Bone and Mineral Research 2013 Annual Meeting
    • Place of Presentation
      Baltimore, MD, USA
    • Data Source
      KAKENHI-PROJECT-23592701
  • [Presentation] A novel therapeutic approach to abdominal aortic aneurysm through the inhibition of osteoclastogenesis.2013

    • Author(s)
      Takei Y, Yamanouchi D, Yoshiko Y
    • Organizer
      5th Hiroshima Conference on Education and Science in Dentistry
    • Place of Presentation
      Hiroshima, Japan
    • Data Source
      KAKENHI-PROJECT-23592701
  • [Presentation] Soluble Klotho does not rescue but rather exaggerates skeletal defects in klotho-deficient mice.2013

    • Author(s)
      Minamizaki T, Konishi Y, Sakurai K, Yoshioka H, Kozai K, Yoshiko Y
    • Organizer
      2nd Joint Meeting of the International Bone and Mineral Society and the Japanese Society for Bone and Mineral Research
    • Place of Presentation
      Kobe, Japan
    • Data Source
      KAKENHI-PROJECT-23592701
  • [Presentation] A novel therapeutic approach to abdominal aortic aneurysm through the inhibition of osteoclastogenesis2013

    • Author(s)
      Takei Yuichiro, Yamaguchi Daisuke, Yoshiko Yuji
    • Organizer
      5th Hiroshima Conference on Education and Science in Dentistry
    • Place of Presentation
      Hiroshima
    • Data Source
      KAKENHI-PROJECT-23592701
  • [Presentation] Imaging mass spectrometry-based molecular histology of bone shows the implication of MEPE-ASARM for the Klotho-deficient phonotype.2013

    • Author(s)
      Fujino Y, Minamizaki T, Sakurai K, Irie Y, Yoshioka H, Takei Y, Kozai K, Okada M, Yoshiko Y
    • Organizer
      The American Society for Bone and Mineral Research 2013 Annual Meeting
    • Place of Presentation
      Baltimore, MD, USA
    • Data Source
      KAKENHI-PROJECT-25462858
  • [Presentation] Imaging mass spectrometry-based molecular histology of bone shows the implication of MEPE-ASARM for the Klotho-deficient phenotype2013

    • Author(s)
      Fujino Yoko, Minamizaki Tomoko, Sakurai Kaoru, Irie Yasumasa, Yosioka Hirotaka, Takei Yuichiro, Kozai Katsuyuki, Okada Mitsugu, Yoshiko Yuji
    • Place of Presentation
      Baltimore, USA
    • Data Source
      KAKENHI-PROJECT-23592701
  • [Presentation] Soluble Klotho does not rescue but rather exaggerates skeletal defects in Klotho-deficient mice.2013

    • Author(s)
      Minamizaki T, Sakurai H, Yoshioka K, Kozai K, Yoshiko Y
    • Organizer
      2nd Joint Meeting of the International Bone and MIneral Society and the Japanese Society for Bone and MIneral Research
    • Place of Presentation
      Kobe, Japan
    • Data Source
      KAKENHI-PROJECT-23592701
  • [Presentation] Soluble Klotho does not rescue but rather exaggerates skeletal defects in klotho-deficient mice.2013

    • Author(s)
      Minamizaki T, Konishi Y, Sakurai K, Yoshioka H, Kozai K, Yoshiko Y
    • Organizer
      2nd Joint Meeting of the International Bone and Mineral Society and the Japanese Society for Bone and Mineral Research
    • Place of Presentation
      Kobe, Japan
    • Data Source
      KAKENHI-PROJECT-25462858
  • [Presentation]2013

    • Author(s)
      Minamizaki Tomoko, Konishi Yukiko, Sakurai Kaoru, Yoshioka Hirotaka, Kozai Katsuyuki, Yoshiko Yuji
    • Organizer
      2nd Joint Meeting of the International Bone and Mineral Society and the Japanese Society for Bone and Mineral Research
    • Place of Presentation
      Kobe
    • Data Source
      KAKENHI-PROJECT-23592701
  • [Presentation] Transient but not Constitutive Activation of ERK Is Necessary for the Unique Action of FGF23 in Bone2012

    • Author(s)
      Minamizaki Tomoko, Konishi Yukiko, Yoshioka Hirotaka, Kozai Katsuyuki, Yoshiko Yuji
    • Organizer
      The American Society for Bone and Mineral Research 2012 Annual Meeting
    • Place of Presentation
      Minneapolis, U.S.A.
    • Year and Date
      2012-10-15
    • Data Source
      KAKENHI-PROJECT-23792105
  • [Presentation] Transient but not Constitutive Activation of ERK Is Necessary for the Unique Action of FGF23 in Bone.2012

    • Author(s)
      Tomoko Minamizaki, Yukiko Konishi, Hirotaka Yoshioka, Kozai Kozai, Yuji Yoshiko
    • Organizer
      The American Society for Bone and Mineral Research 2012 Annual Meeting
    • Place of Presentation
      Minneapolis, USA
    • Data Source
      KAKENHI-PROJECT-23792105
  • [Presentation] Phosphate Regulates Fibromodulin Expression Through the ERK Pathway in Ameloblasts2012

    • Author(s)
      Yoshioka Hirotaka, Yoshiko Yuji, Irie Yasumasa, Minamizaki Tomoko, Kato Yukio, Sugiyama Toshihiro, Maeda Norihiko
    • Organizer
      The 41st Annual Meeting of the American Association for Dental Research
    • Place of Presentation
      Tampa, U.S.A
    • Year and Date
      2012-03-23
    • Data Source
      KAKENHI-PROJECT-23792105
  • [Presentation] Transient but not constitutive activation of ERK is necessary for the unique actions of FGF23 in bone2012

    • Author(s)
      Minamizaki Tomoko, Konishi Yukiko, Yoshioka Hirotaka, Kozai Katsuyuki, Yoshiko Yuji
    • Organizer
      The American Society for Bone and Mineral Research 2012 Annual Meeting
    • Place of Presentation
      Minneapolis, USA
    • Data Source
      KAKENHI-PROJECT-23592701
  • [Presentation] Transient but not constitutive activation of ERK is necessary for the unique actions of FGF23 in bone.2012

    • Author(s)
      Minamizaki T, Konishi Y, Yoshioka H, Kozai K, Yoshiko Y
    • Organizer
      The American Society for Bone and Mineral Research 2012 Annual Meeting
    • Place of Presentation
      Minneapolis, Minnesota, USA
    • Data Source
      KAKENHI-PROJECT-23592701
  • [Presentation] 細胞外リン酸は ERK1/2 のシグナルを介してエナメル芽細胞における Fibromodulin 遺伝子の発現を抑制する2011

    • Author(s)
      入江泰正,吉岡広陽,吉子裕二,南崎朋子,加藤幸夫,前田憲彦
    • Organizer
      第53回 歯科基礎医学会学術大会
    • Place of Presentation
      岐阜
    • Year and Date
      2011-10-01
    • Data Source
      KAKENHI-PROJECT-23792105
  • [Presentation] MEPE由来リン酸化ASARMとPhexはFGF23/可溶型Klothoによる石灰化の負の調節系と関連する2011

    • Author(s)
      小西有希子,吉子裕二他
    • Organizer
      日本骨代謝学会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-23592701
  • [Presentation] FGFシグナルによる石灰化調節:FGF23-Phex経路を中心として2011

    • Author(s)
      南崎朋子,吉子裕二,小西有希子,吉岡広陽,香西克之,前田憲彦
    • Organizer
      第29回日本骨代謝学会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-23592701
  • [Presentation] MEPE-derived phosphorylated ASARM is involved in FGF23/soluble Klotho-dependent hypomineralization.2011

    • Author(s)
      Konishi Y, Yoshiko Y, et al.
    • Organizer
      American Society for Bone and Mineral Research 2012 Annual Meeting.
    • Place of Presentation
      San Diego (USA)
    • Data Source
      KAKENHI-PROJECT-23592701
  • [Presentation] FGFシグナルによる石灰化調節:FGF23-Phex経路を中心として2011

    • Author(s)
      南崎朋子,吉子裕二他
    • Organizer
      日本骨代謝学会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-23592701
  • [Presentation] MEPE=derived phosphorylated ASARM is involved in FGF23/soluble Klotho-dependent hypomineralization2011

    • Author(s)
      Konishi Yukiko, Yoshiko Yuji, MInamizaki Tomoko, Yoshioka Hirotaka, Kozai Katsuyuki, Aubin Jane E, Maeda Norihiko
    • Organizer
      The American Society for Bone and Mineral Research 2012 Annual Meeting
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-23592701
  • [Presentation] MEPE-derived phosphorylated ASARM is involved in FGF23/soluble Klotho-dependent hypomineralization2011

    • Author(s)
      Konishi Yukiko, Minamizaki Tomoko, Yoshiko Yuji, Yoshioka Hirotaka, Kozai Katsuyuki, Jane E. Aubin, Maeda Norihiko
    • Organizer
      The American Society for Bone and Mineral Research 2011 Annual Meeting
    • Place of Presentation
      San Diego, U.S.A
    • Data Source
      KAKENHI-PROJECT-23792105
  • [Presentation] MEPE-associated phosphorylated ASARM is a potential target to facilitate bone mineralization2011

    • Author(s)
      Mohri Maya, Yoshiko Yuji, Minamizaki Tomoko, Yoshioka Hirotaka, Maeda Norihiko
    • Organizer
      4th Hiroshima Conference on Education and Science in Dentistry
    • Place of Presentation
      Hiroshima
    • Year and Date
      2011-10-10
    • Data Source
      KAKENHI-PROJECT-23792105
  • [Presentation] 骨の石灰化調節に関わる可溶化型Klotho-FGF23 基軸2011

    • Author(s)
      南崎朋子、吉子裕二、吉岡広陽、前田憲彦
    • Organizer
      日本解剖学会第66回中国・四国支部学術集会
    • Place of Presentation
      徳島
    • Year and Date
      2011-11-13
    • Data Source
      KAKENHI-PROJECT-23792105
  • [Presentation] FGF シグナルによる石灰化調節:FGF23-Phex 経路を中心として2011

    • Author(s)
      南崎朋子,吉子裕二,小西有希子,吉岡広陽,香西克之,前田憲彦
    • Organizer
      第29回日本骨代謝学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2011-07-28
    • Data Source
      KAKENHI-PROJECT-23792105
  • [Presentation] MEPE 由来リン酸化 ASARM と Phex は FGF23/可溶型Klotho による石灰化の負の調節系と関連する2011

    • Author(s)
      小西有希子,吉子裕二,南崎朋子,吉岡広陽,香西克之,前田憲彦
    • Organizer
      第29回日本骨代謝学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2011-07-28
    • Data Source
      KAKENHI-PROJECT-23792105
  • [Presentation] MEPE由来リン酸化ASARMとPhexはFGF23/可溶型Klothoによる石灰化の負の調節系と関連する2011

    • Author(s)
      小西有希子,吉子裕二,南崎朋子,吉岡広陽,香西克之,前田憲彦
    • Organizer
      第29回日本骨代謝学会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-23592701
  • [Presentation] Soluble Klotho Acts as a Coactivator of FGF23 in Bone but not in Kidney to Regulate Mineralization.2010

    • Author(s)
      Minamizaki T, Yoshiko Y, Konishi Y、Yoshioka H, et al.
    • Organizer
      The 32nd Annual Meeting of the American Society for Bone and Mineral Research
    • Place of Presentation
      Toronto
    • Data Source
      KAKENHI-PROJECT-20592139
  • [Presentation] III型ナトリウム依存性リン酸トランスポーターPit1の過剰発現は歯のエナメル質形成に影響し, 骨・ミネラル代謝異常の発症とともに増悪する2010

    • Author(s)
      錦織亜矢, 吉岡広陽, 吉子裕二, 南崎朋子, 他
    • Organizer
      第52回歯科基礎医学会学術大会
    • Place of Presentation
      東京
    • Year and Date
      2010-09-22
    • Data Source
      KAKENHI-PROJECT-20592139
  • [Presentation] III型ナトリウム依存性リン酸トランスポーターPit1の過剰発現は骨・ミネラル代謝に先行して歯のエナメル質形成に障害をきたす2010

    • Author(s)
      吉岡広陽, 吉子裕二, 南崎朋子, 他
    • Organizer
      第28回日本骨代謝学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2010-07-21
    • Data Source
      KAKENHI-PROJECT-20592139
  • [Presentation] Overexpression of the type III sodium-dependent phosphate transporter Pit1 markedly perturbs enamel formation during tooth development.2010

    • Author(s)
      Yoshioka H, Yoshiko Y, Minamizaki T, et al.
    • Organizer
      The 32nd Annual Meeting of the American Society for Bone and Mineral Research
    • Place of Presentation
      Toronto
    • Year and Date
      2010-10-17
    • Data Source
      KAKENHI-PROJECT-20592139
  • [Presentation] 老化関連タンパクKlothoによる骨の石灰化調節機構2010

    • Author(s)
      小西有希子, 吉子裕二, 南崎朋子, 吉岡広陽, 他
    • Organizer
      第43回広島大学歯学会総会
    • Year and Date
      2010-06-12
    • Data Source
      KAKENHI-PROJECT-20592139
  • [Presentation] III型Na/Pi共輸送担体Pit1過剰発現ラットはエナメル質の石灰化不全を来す2009

    • Author(s)
      小間義朗, 吉岡広陽, 吉子裕二, 南崎朋子, 他
    • Organizer
      第42回広島大学歯学会総会
    • Place of Presentation
      広島
    • Data Source
      KAKENHI-PROJECT-20592139
  • [Presentation] III型Na/Pi共輸送担体Pit1過剰発現ラットはエナメル質の形成不全をきたす2009

    • Author(s)
      吉岡広陽, 吉子裕二, 南崎朋子, 前田憲彦
    • Organizer
      第51回歯科基礎医学会学術大会
    • Place of Presentation
      新潟
    • Year and Date
      2009-09-10
    • Data Source
      KAKENHI-PROJECT-20592139
  • [Presentation] PTHと活性型ビタミンD_3は骨芽細胞におけるFGF23の発現とシグナル伝達に相反的に関与し,基質石灰化を調節する2009

    • Author(s)
      南崎朋子, 吉子裕二, 吉岡広陽, 前田憲彦
    • Organizer
      第27回日本骨代謝学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2009-07-23
    • Data Source
      KAKENHI-PROJECT-20592139
  • [Presentation] A Parathyroid Hormone-1α,25-dihydroxy-vitamin D_3-FGF23 Loop Regulating Bone Mineralization in Cultured Rat Calvaria Osteoblasts.2009

    • Author(s)
      Minamizaki T, Yoshiko Y, Yoshioka H, Aubin JE, Maeda N
    • Organizer
      The 31st Annual Meeting of the American Society for Bone and Mineral Research
    • Place of Presentation
      Denver, USA
    • Year and Date
      2009-09-14
    • Data Source
      KAKENHI-PROJECT-20592139
  • [Presentation] III型Na/Pi共輸送担体Pit1過剰発現ラットはエナメル質の形成不全を来す2009

    • Author(s)
      吉岡広陽, 吉子裕二, 南崎朋子, 鈴木敦詞, 伊藤光泰, 前田憲彦
    • Organizer
      第27回日本骨代謝学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2009-07-23
    • Data Source
      KAKENHI-PROJECT-20592139
  • [Presentation] FGF23 and FGF2 share a common but also have distinct signaling pathways for negative regulation of bone nodule mineralization in cultured osteoblasts.2008

    • Author(s)
      Minamizaki T, Yoshiko Y, Suzuki S, et al.
    • Organizer
      The 30th Annual Meeting of the American Society for Bone and Mineral Research
    • Place of Presentation
      Montreal
    • Year and Date
      2008-09-13
    • Data Source
      KAKENHI-PROJECT-20592139
  • [Presentation] 1,25(OH)_2D_3、PTHおよびKlothoはFGF23の基質石灰化抑制作用を直接調節する2008

    • Author(s)
      南崎朋子, 吉子裕二, 前田憲彦
    • Organizer
      第50回歯科基礎医学会
    • Place of Presentation
      東京
    • Year and Date
      2008-09-23
    • Data Source
      KAKENHI-PROJECT-20592139
  • [Presentation] Gene expression profiling of FGF23-overexpressing, mineralization-defective rat calvaria osteoblasts uncovers both known and novel mineralization mechanisms.2007

    • Author(s)
      Yoshiko, Y.
    • Organizer
      17th Scientific Meeting International Bone & Mineral Society
    • Place of Presentation
      Montreal
    • Data Source
      KAKENHI-PROJECT-18592001
  • [Presentation] Gene expression profiling of FGF23-overexpression, mineralization defective rat calvaria osteoblast uncovers both known and novel mineralization mechanisms2007

    • Author(s)
      Yuji, Yoshiko
    • Organizer
      The 17th Scientific Meeting of International Bone and Mineral Society
    • Place of Presentation
      Montreal
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18592001
  • [Presentation] Gene expression profiling of FGF23-overexpression, mineralization defective rat calvaria osteoblasts uncovers both known and novel mineralization mechanis.2007

    • Author(s)
      Yuji Yoshiko
    • Organizer
      The 17th Scientific Meeting of International Bone and Mineral Society
    • Place of Presentation
      モントリオール
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18592001
  • [Presentation] 骨基質タンパクMEPE-由来ASARMは血中リン濃度非依存的に骨量を減少させる

    • Author(s)
      櫻井薫、南崎朋子、川本真貴子、藤野陽子、竹井悠一郎、吉岡広陽、岡田 貢、香西克之、吉子裕二
    • Organizer
      日本解剖学会第69回中国・四国支部学術集会
    • Place of Presentation
      広島
    • Year and Date
      2014-10-25 – 2014-10-26
    • Data Source
      KAKENHI-PROJECT-25462858
  • [Presentation] Phexの基質MEPE-ASARMは血中リン濃度非依存的に骨量を減少させる

    • Author(s)
      櫻井薫、南崎朋子、吉岡広陽、竹井悠一郎、香西克之、吉子裕二
    • Organizer
      日本骨代謝学会
    • Place of Presentation
      大阪
    • Year and Date
      2014-07-24 – 2014-07-26
    • Data Source
      KAKENHI-PROJECT-25462858
  • [Presentation] MEPE-ASARM, a substrate of Phex, decreases bone volume independently of serum phosphate levels

    • Author(s)
      Sakurai K, Minamizaki T, Yoshioka H, Takei Y, Kozai K, Yoshiko Y
    • Organizer
      The American Society for Bone and Mineral Research 2014 Annual Meeting
    • Place of Presentation
      Houston(USA)
    • Year and Date
      2014-09-12 – 2014-09-15
    • Data Source
      KAKENHI-PROJECT-25462858
  • [Presentation] Klotho欠損マウス腎臓のイメージング質量分析

    • Author(s)
      藤野陽子、南崎朋子、宮脇聡子、川上朝子、宮地孝明、櫻井薫、竹井悠一郎、吉岡広陽、香西克之、岡田貢、吉子裕二
    • Organizer
      日本解剖学会第69回中国・四国支部学術集会
    • Place of Presentation
      広島
    • Year and Date
      2014-10-25 – 2014-10-26
    • Data Source
      KAKENHI-PROJECT-25462858
  • 1.  MINAMIZAKI Tomoko (30452593)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 59 results
  • 2.  YOSHIOKA Hirotaka (50523411)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 50 results
  • 3.  MAEDA Norihiko (60049418)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 4 results
  • 4.  KOZAI Katsuyuki (10178212)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 16 results
  • 5.  WANG Hua (50363081)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 6 results
  • 6.  UCHIDA Soshi (60330990)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  FUTAMURA MANABU (10415515)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  NIIDA Shunpei (10137630)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 9.  Hiyama Shinji (60314754)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  Kagawa Kazuko (60432671)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 11.  SUZUKI Atsushi (90340265)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 12.  SUEMUNE Setsuko (80112209)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  KODAMA Ichiro (00325169)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  ZHANG Yan (50332797)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  津賀 一弘 (60217289)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  宮宗 秀伸 (80422252)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  河野 尚平 (00868391)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  谷本 幸太郎 (20322240)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  加藤 功一 (50283875)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  國松 亮 (40580915)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  TAKEI Yuichiro
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 22.  OKITA Saki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 23.  NAKANO Masashi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  田中 雅治
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  Ahmed Faisal
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  Sarmin Nushrat
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  Zaurasari Mentari
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  外丸 祐介
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 29.  中尾 裕子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 30.  宮地 孝明
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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