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OZONO Keiichi  大薗 恵一

ORCIDConnect your ORCID iD *help
… Alternative Names

大薗 恵一  オオゾノ ケイイチ

大薗 惠一  オオゾノ ケイイチ

大ぞつ 恵一  オオゾツ ケイイチ

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Researcher Number 20270770
Other IDs
External Links
Affiliation (Current) 2025: 大阪大学, 大学院連合小児発達学研究科, 招へい教授
Affiliation (based on the past Project Information) *help 2023: 大阪大学, 大学院連合小児発達学研究科, 招へい教授
2021 – 2022: 大阪大学, 大学院医学系研究科, 教授
2017 – 2021: 大阪大学, 医学系研究科, 教授
2013 – 2014: 大阪大学, 医学(系)研究科(研究院), 教授
2002 – 2012: Osaka University Graduate School of Medicine, Department of Pediatrics, Professor, 医学系研究科, 教授 … More
2011: 大阪大学, 医学系・研究科, 教授
2003: Osaka University Graduate School Medicine, Department of Pediatrics, Professor, 大学院・医学研究科・生体統合医学・小児発達医学, 教授
2003: 大阪大学, 大学院・医学系研究科・生体統合医学・小児発達医学, 教授
2002: 大阪大学, 大学院・医学系研究科・生体統合医学 小児発達医学, 教授
1997 – 2001: Osaka Med.Center for Matern.and Child Health, Director, 環境影響部門, 部長
1999: 大阪府立母子保健総合医療センター, 研究所, 部長
1999: Osaka Medical Center and Research Institute for Maternal and Child Health, Department of Environmental Medicine, Professor, 部長
1996: 大阪市立母子保健総合医療センター, 研究所, 部長
1996: 大阪府立母子保健総合医療センター, 研究所・環境影響部門, 部長
1996: 大阪府立母子保健総合医療センター研究所, 環境影響部門, 研究員
1996: 大阪府立田子保健総合医療センター研究所, 部長 Less
Review Section/Research Field
Principal Investigator
Pediatrics / Basic Section 52050:Embryonic medicine and pediatrics-related / Kidney internal medicine / 内分泌・代謝学
Except Principal Investigator
Pediatrics / Pediatrics / Orthodontics/Pediatric dentistry
Keywords
Principal Investigator
骨系統疾患 / ビタミンD / 骨折 / 骨形成不全症 / SHOX / transgenic mouse / vitamin D / メガリン / 成長 / FGF23 … More / 骨形成 / 骨粗鬆症 / ビタミンD受容体 / ビタミンD応答配列 / 骨芽細胞 / くる病 / 骨疾患 / 代謝性骨疾患 / リン代謝 / 遺伝子発現 / 低リン血症性くる病 / 骨細胞 / 薬剤開発 / 遺伝子診断 / モデルマウス / iPS細胞 / 成長軟骨帯 / 骨石灰化 / ノックインマウス / 脆弱性骨折 / 疾患特異的iPS細胞 / 骨脆弱性 / glucocorticoid / progeria / skeletal dysplasia / PTPN11 / gene trap / overgrowth / short stature / SHOX遺伝子 / 軟骨低形成症 / Noonan症候群 / PTRN11遺伝子 / グルココルチコイド / 早老症 / PTPN11遺伝子 / ジーントラップ法 / 過成長 / 低身長 / GST-fusion protein / receptor-associated protein / megalin / receptor-associated protein(RAP) / GST融合蛋白 / receptor-associated protein (RAP) / kidney organ culture / renal tubules / transcription activation / promoter / 1 alpha-hydroxylase / digoxigenin / forskolin / 転写活性 / プロモーター / 胎仔 / 2重染色 / in situ hybridization / 腎尿細管 / 腎器官培養 / 1α位水酸化酵素 / 創薬 / cGMP / 成長軟骨 / C型Na利尿ペプチド / 成長障害 / 臍帯血 / ビスフォスフォネート / 骨 / klotho / カルシウム / リン / Wntシグナル / 骨量 / wntシグナル / カルシウム調節ホルモン / レポーター / 副甲状腺ホルモン / 24位水酸化酵素 / 遺伝子クローニング / ビタミンD代謝 / 遺伝子発現抑制 / 1位水酸化酵素 / 遺伝子プロモーター / プロモーター活性 / 高カルシウム血症 / 悪性腫瘍 / 転写抑制 / 副甲状腺関連蛋白 … More
Except Principal Investigator
肝線維化 / Grb10 / pQCT / Lrp6 / osteoprotegerin / 遺伝子治療 / RANKL / TGF-β / IL-6 / 象牙質形成不全 / セメント質形成不全 / 乳歯の早期脱落 / 酵素補充療法 / 骨形成不全症 / 低ホスファターゼ症 / 骨系統疾患 / Hepatic stellate cell / Hepatocyte damage / Hepatic fibrosis / Tyrosine kinase type receptor / 偽胆管 / 肝硬変 / SH2ドメイン / 肝星細胞 / 肝細胞障害 / チロシンキナーゼ型受容体 / Wnt signaling / spina bifida / スクリーニング / 催奇性薬剤 / 葉酸 / Wntシグナル / 二分脊椎 / gene therapy / bone metastasis / neuroblastoma / 筋肉内遺伝子導入 / 破骨細胞 / 骨転移 / 神経芽細胞腫 / Peptide / Liver fibrosis / ペプチド / bile duct epithelial cell / primary culture of hepatocytes / Jagged 1 gene / hepatic fibrosis / 胆管上皮細胞 / 初代培養肝細胞 / Jagged1遺伝子 / cyclic AMP / Gsalpha mutation / McCune-Albright syndrome / Pagets disease / osteoclast / Gsα protein / fibrous dysplasia / cAMP / Gsαタンパク変異 / McCune-Albright症候群 / 遺伝子転写 / 核内受容体 / ビタミンD受容体 / ビタミンD / ステロイド・ホルモン / 共役因子 / 核受容体 / PTHrP / AR / ER / VDR / TGFβ / レチノイド / 白血病 / 前立腺癌 / 乳癌 Less
  • Research Projects

    (19 results)
  • Research Products

    (119 results)
  • Co-Researchers

    (34 People)
  •  Analysis of dysfunction of osteocytes to reveal the targets of treatment in genetical bone diseasesPrincipal Investigator

    • Principal Investigator
      Ozono Keiichi
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Osaka University
  •  Analysis of mechanism of bone fragility and effects of drugs in osteogenesis imperfecta using a graft model for enchondral bone formationPrincipal Investigator

    • Principal Investigator
      Ozono Keiichi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Osaka University
  •  Basic and clinical approaches for dental problems associated with skeletal diseases

    • Principal Investigator
      OKAWA RENA
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthodontics/Pediatric dentistry
    • Research Institution
      Osaka University
  •  Ozono KeiichiPrincipal Investigator

    • Principal Investigator
      OZONO Keiichi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pediatrics
    • Research Institution
      Osaka University
  •  Role of FGF23 in metabolic bone diseasesPrincipal Investigator

    • Principal Investigator
      OZONO Keiichi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Osaka University
  •  The effect of calcitropic hormone on bone forming action of・-cateninsignalPrincipal Investigator

    • Principal Investigator
      OZONO Keiichi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Osaka University
  •  Molecular biological assessment of hepatocyte damage and fibrosis in intractable pediatric liver diseases

    • Principal Investigator
      MUSHIAKE Sotaro
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Osaka University
  •  Study for the development of screening method for the teratogenic medicine using spina bifida model mice

    • Principal Investigator
      SAKAI Norio
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Osaka University
  •  Analysis of height-determining gene.Principal Investigator

    • Principal Investigator
      OZONO Keiichi
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pediatrics
    • Research Institution
      Osaka University
  •  A Study for Clinical Application of TGP-β Activation-Inhibitory Peptide "LSKL" for Progressive Liver Damage

    • Principal Investigator
      MUSHIAKE Sotaro
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Osaka University
  •  Development of Organ-specific Treatment for Bone Metastasis in Neuroblastoma

    • Principal Investigator
      MICHIGAMI Toshimi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Osaka Medical Center and Research Institute for Maternal and Child Health
  •  Functional analysis of megalin, a key molecule of reabsorption in renal tubular cells ; making and using RAP-transgenic micePrincipal Investigator

    • Principal Investigator
      OZONO Keiichi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Osaka University
      Research Institute, Osaka Medical Center for Maternal and Child Health
  •  Characterization of the expression of 1 alpha-hydroxylase in kidney and application to renal failurePrincipal Investigator

    • Principal Investigator
      OZONO Keiichi
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Research Institute, Osaka Medical Center for Maternal and Child Health
  •  ホルモンによるがん増殖制御機構とその臨床応用

    • Principal Investigator
      尾形 悦郎
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Japanese Foundation For Cancer Research
  •  A Study of Expression and Function of Jagged 1 Gene Relating the Development of Intrahepatic Bile Ducts and Bile Ductule Proliferation in Hepatic Fibrosis.

    • Principal Investigator
      TAJIRI Hitoshi
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Osaka University
  •  ビタミンD応答配列(VDRE)の解析 positive vs negative VDREPrincipal Investigator

    • Principal Investigator
      大薗 恵一
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      内分泌・代謝学
    • Research Institution
      Research Institute, Osaka Medical Center for Maternal and Child Health
  •  ビタミンD受容体の遺伝子転写制御活性を有する部位の検討

    • Principal Investigator
      NAKAJIMA Shigeo
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Research Institute, Osaka Medical Center for Maternal and Child Health
  •  骨芽細胞におけるPTHrP産生とビタミンDによる調節Principal Investigator

    • Principal Investigator
      大薗 恵一
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      内分泌・代謝学
    • Research Institution
      Research Institute, Osaka Medical Center for Maternal and Child Health
  •  Gsalpha mutation and increased production of cAMP and IL-6 in patients with McCune-Albright syndrome.

    • Principal Investigator
      SHIMA Masaaki, 山本 威久
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Osaka University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation Book

  • [Book] 整形・災害外科「骨系統疾患と骨粗鬆症」2023

    • Author(s)
      大薗恵一
    • Total Pages
      10
    • Publisher
      金原出版
    • Data Source
      KAKENHI-PROJECT-21H02881
  • [Book] 骨研究最前線 アンチ・エイジングシリーズ No.3 代謝・疾患のメカニズムから再生医療・創薬・リハビリ機器・機能性食品開発まで2013

    • Author(s)
      大薗恵一
    • Publisher
      エヌ・ティー・エス
    • Data Source
      KAKENHI-PROJECT-24390264
  • [Book] ビタミンDと疾患 改訂版 -基礎の理解と臨床への応用-2013

    • Author(s)
      大薗恵一
    • Publisher
      医薬ジャーナル社
    • Data Source
      KAKENHI-PROJECT-24390264
  • [Book] 今日の小児治療指今日の小児治療指針第15版2012

    • Author(s)
      大薗恵一
    • Publisher
      医学書院
    • Data Source
      KAKENHI-PROJECT-21591319
  • [Book] 小児腎臓病学2012

    • Author(s)
      大薗恵一
    • Publisher
      診断と治療社
    • Data Source
      KAKENHI-PROJECT-21591319
  • [Book] 今日の治療指針私はこう治療している2012

    • Author(s)
      大薗恵一
    • Total Pages
      1188
    • Publisher
      医学書院
    • Data Source
      KAKENHI-PROJECT-21591319
  • [Book] 今日の小児治療指針第15版2012

    • Author(s)
      大薗恵一
    • Publisher
      医学書院
    • Data Source
      KAKENHI-PROJECT-21591319
  • [Book] 骨粗鬆症診療ハンドブック 改訂5版2012

    • Author(s)
      大薗恵一
    • Publisher
      医薬ジャーナル社
    • Data Source
      KAKENHI-PROJECT-24390264
  • [Book] 小児科診療ガイドライン-最新の診療指針-第2版2011

    • Author(s)
      大薗恵一
    • Publisher
      総合医学社
    • Data Source
      KAKENHI-PROJECT-21591319
  • [Book] 今日の治療指針-私はこう治療している-くる病2008

    • Author(s)
      大薗恵一
    • Publisher
      医学書院
    • Data Source
      KAKENHI-PROJECT-19591204
  • [Book] 今日の治療指針-私はこう治療している-2008

    • Author(s)
      大薗 恵一
    • Publisher
      医学書院
    • Data Source
      KAKENHI-PROJECT-19591204
  • [Book] 小児科学第3版8章先天代謝異常症, 代謝疾患Jくる病Rickets2008

    • Author(s)
      大薗恵一
    • Publisher
      医学書院
    • Data Source
      KAKENHI-PROJECT-19591204
  • [Book] 小児科学第3版 8章 先天代謝異常症, 代謝疾患 J くる病 Rickets2008

    • Author(s)
      大薗 恵一
    • Publisher
      医学書院
    • Data Source
      KAKENHI-PROJECT-19591204
  • [Book] 小児科診療ガイドライン-最新の診療指針-2007

    • Author(s)
      大薗 恵一
    • Publisher
      総合医学社
    • Data Source
      KAKENHI-PROJECT-19591204
  • [Journal Article] Complex intrinsic abnormalities in osteoblast lineage cells of X-linked hypophosphatemia: Analysis of human iPS cell models generated by CRISPR/Cas9-mediated gene ablation2024

    • Author(s)
      Nakanishi Tatsuro、Yamazaki Miwa、Tachikawa Kanako、Ueta Ayu、Kawai Masanobu、Ozono Keiichi、Michigami Toshimi
    • Journal Title

      Bone

      Volume: 181 Pages: 117044-117044

    • DOI

      10.1016/j.bone.2024.117044

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07835, KAKENHI-PROJECT-21K07881, KAKENHI-PROJECT-22K07837, KAKENHI-PROJECT-21H02881
  • [Journal Article] Self-Administration of Burosumab in Children and Adults with X-Linked Hypophosphataemia in Two Open-Label, Single-Arm Clinical Studies2023

    • Author(s)
      Kubota Takuo、Namba Noriyuki、Tanaka Hiroyuki、Muroya Koji、Imanishi Yasuo、Takeuchi Yasuhiro、Kanematsu Masanori、Sun Wei、Seino Yoshiki、Ozono Keiichi
    • Journal Title

      Advances in Therapy

      Volume: 40 Issue: 4 Pages: 1530-1545

    • DOI

      10.1007/s12325-022-02412-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07797, KAKENHI-PROJECT-22K08315, KAKENHI-PROJECT-21H02881
  • [Journal Article] Association of trabecular bone score and bone mineral apparent density with the severity of bone fragility in children and adolescents with osteogenesis imperfecta: A cross-sectional study2023

    • Author(s)
      Ohata Yasuhisa、Kitaoka Taichi、Ishimi Takeshi、Yamada Chieko、Nakano Yukako、Yamamoto Kenichi、Takeyari Shinji、Nakayama Hirofumi、Fujiwara Makoto、Kubota Takuo、Ozono Keiichi
    • Journal Title

      PLOS ONE

      Volume: 18 Issue: 8 Pages: e0290812-e0290812

    • DOI

      10.1371/journal.pone.0290812

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K15940, KAKENHI-PROJECT-21H02881
  • [Journal Article] Phosphate promotes osteogenic differentiation through non-canonical Wnt signaling pathway in human mesenchymal stem cells2022

    • Author(s)
      Rui Shumin、Kubota Takuo、Ohata Yasuhisa、Yamamoto Kenichi、Fujiwara Makoto、Takeyari Shinji、Ozono Keiichi
    • Journal Title

      Bone

      Volume: 164 Pages: 116525-116525

    • DOI

      10.1016/j.bone.2022.116525

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21H02881, KAKENHI-PROJECT-20K08256
  • [Journal Article] 4-Phenylbutyric acid enhances the mineralization of osteogenesis imperfecta iPSC-derived osteoblasts2021

    • Author(s)
      Takeyari Shinji、Kubota Takuo、Ohata Yasuhisa、Fujiwara Makoto、Kitaoka Taichi、Taga Yuki、Mizuno Kazunori、Ozono Keiichi
    • Journal Title

      Journal of Biological Chemistry

      Volume: 296 Pages: 100027-100027

    • DOI

      10.1074/jbc.ra120.014709

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08256, KAKENHI-PROJECT-18K15708, KAKENHI-PROJECT-18H02780, KAKENHI-PROJECT-21H02881
  • [Journal Article] Comprehensive genetic analyses using targeted next-generation sequencing and genotype-phenotype correlations in 53 Japanese patients with osteogenesis imperfecta2019

    • Author(s)
      Ohata Y., Takeyari S., Nakano Y., Kitaoka T., Nakayama H., Bizaoui V., Yamamoto K., Miyata K., Yamamoto K., Fujiwara M., Kubota T., Michigami T., Yamamoto K., Yamamoto T., Namba N., Ebina K., Yoshikawa H., Ozono K.
    • Journal Title

      Osteoporosis International

      Volume: 30 Issue: 11 Pages: 2333-2342

    • DOI

      10.1007/s00198-019-05076-6

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15708, KAKENHI-PROJECT-17K10076, KAKENHI-PROJECT-18H02780
  • [Journal Article] Early exfoliation of permanent tooth in patient with hypophosphatasia2017

    • Author(s)
      Okawa Rena、Miura Jiro、Kokomoto Kazuma、Kubota Takuo、Kitaoka Taichi、Ozono Keiichi、Nakano Kazuhiko
    • Journal Title

      Pediatric Dental Journal

      Volume: 27 Issue: 3 Pages: 173-178

    • DOI

      10.1016/j.pdj.2017.08.005

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K11364
  • [Journal Article] Gene therapy improves dental manifestations in hypophosphatasia model mice2017

    • Author(s)
      Okawa R, Iijima O, Kishino M, Okawa H, Toyosawa S, Sugano-Tajima H, Shimada T, Okada T, Ozono K, Ooshima T, Nakano K.
    • Journal Title

      Journal of Periodontal Research

      Volume: 印刷中 Issue: 3 Pages: 471-478

    • DOI

      10.1111/jre.12412

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K11364
  • [Journal Article] Oral manifestations of Japanese patients with osteogenesis imperfecta2017

    • Author(s)
      Okawa R, Kubota T, Kitaoka T, Kokomoto K, Ozono K, Nakano K.
    • Journal Title

      Pediatric Dental Journal

      Volume: 印刷中 Issue: 2 Pages: 73-78

    • DOI

      10.1016/j.pdj.2017.02.001

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K11364
  • [Journal Article] Report of two dental patients diagnosed with hypophosphatasia2016

    • Author(s)
      Rena Okawa, Taichi Kitaoka, Kanae Saga, Keiich Ozono and Kazuhiko Nakano
    • Journal Title

      Journal of Clinical Case Reports

      Volume: 6 Issue: 02 Pages: 704-704

    • DOI

      10.4172/2165-7920.1000704

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K11364
  • [Journal Article] 小児における血清NT-proCNP値測定の意義-年齢,成長速度及びGH治療反応性-2014

    • Author(s)
      窪田拓生,三浦弘司,王薇,北岡太一,大幡泰久,山本景子,藤原誠,橘真紀子,三善陽子,難波範行,大薗恵一
    • Journal Title

      ホルモンと臨床

      Volume: 60 Pages: 41-43

    • Data Source
      KAKENHI-PROJECT-24390264
  • [Journal Article] Overgrowth syndrome associated with a gain-of-functionmutation of the natriuretic   peptide receptor 2 (NPR2) gene.2014

    • Author(s)
      Miura K, Kim OH, Lee HR, Namba N, Michigami T, Yoo WJ, Choi H, Ozono K, Cho TJ.
    • Journal Title

      Am J Med Genet A

      Volume: 164A Issue: 1 Pages: 156-163

    • DOI

      10.1002/ajmg.a.36218

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390264
  • [Journal Article] Weaver syndrome and EZH2 mutations:Clarifying the clinical phenotype.2013

    • Author(s)
      Ozono K
    • Journal Title

      Am J Med Gene A

      Volume: 161A(12) Pages: 2972-2980

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390264
  • [Journal Article] 遺伝性骨粗鬆症2013

    • Author(s)
      大薗恵一
    • Journal Title

      最新の骨粗鬆症学-骨粗鬆症の最新知見-

      Volume: 71  増刊号2 Pages: 583-588

    • Data Source
      KAKENHI-PROJECT-24390264
  • [Journal Article] Pediatric aspects of skeletal dysplasia.2012

    • Author(s)
      Ozono K
    • Journal Title

      Pediatr Endocrinol Rev

      Volume: 10 Suppl 1 Pages: 35-43

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390264
  • [Journal Article] 現代の栄養欠乏としてのビタミンD欠乏2012

    • Author(s)
      大薗恵一
    • Journal Title

      Vitamins(Japan)

      Volume: 86(1) Pages: 28-31

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591319
  • [Journal Article] 現代の栄養欠乏としてのビタミンD欠乏2012

    • Author(s)
      大薗恵一
    • Journal Title

      Vitamins (Japan)

      Volume: 86(1) Pages: 28-31

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591319
  • [Journal Article] 可溶型α-Klotho濃度測定の意義2012

    • Author(s)
      大幡泰久, 大薗恵一
    • Journal Title

      季刊腎と骨代謝

      Volume: 25(1) Pages: 41-46

    • Data Source
      KAKENHI-PROJECT-21591319
  • [Journal Article] Linear nevus sebaceous syndrome with hypophosphatemic rickets with elevated FGF-232012

    • Author(s)
      Narazaki R, Ihara K, Namba N, Matsuzaki H, Ozono K, Hara T.
    • Journal Title

      Pediatr Nephrol

      Volume: 27(5) Pages: 861-863

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591319
  • [Journal Article] Lysosomal storage causes cellular dysfunction in mucolipidosis II skin fibroblasts2011

    • Author(s)
      Otomo T, Higaki K, Nanba E, Ozono K, Sakai N.
    • Journal Title

      J Biol Chem

      Volume: 286(40) Pages: 35283-35290

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591319
  • [Journal Article] A Male Patient with Humoral Hypercalcemia of Malignancy(HHM) with Leukocytosis Caused by Cutaneous Squamous Cell Carcinoma Resulting from Recessive Dystrophic Epidermolysis Bullosa2011

    • Author(s)
      Miura K, Umegaki N, Kitaoka T, Kubota T, Namba N, Etani Y, Hirai H, Kogaki S, Nakajima S, Takahashi Y, Tamai K, Katayama I, Ozono K.
    • Journal Title

      Clin Pediatr Endocrinol

      Volume: 20(3) Pages: 65-71

    • NAID

      10031199629

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591319
  • [Journal Article] 小児とビタミンD2011

    • Author(s)
      大薗恵一
    • Journal Title

      THE BONE

      Volume: 25(3) Pages: 105-110

    • Data Source
      KAKENHI-PROJECT-21591319
  • [Journal Article] 子どもの骨・関節疾患.診断と治療2011

    • Author(s)
      大薗恵一
    • Journal Title

      総合臨床

      Volume: 60(10) Pages: 2151-2152

    • Data Source
      KAKENHI-PROJECT-21591319
  • [Journal Article] Circulating levels of soluble alpha-Klotho are markedly elevated in human umbilical cord blood2011

    • Author(s)
      Ohata Y, Arahori H, Namba N, Kitaoka T, Hirai H, Wada K, Nakayama M, Michigami T, Imura A, Nabeshima Y, Yamazaki Y, Ozono K.
    • Journal Title

      J Clin Endocrinol Metab

      Volume: 96(6) Pages: 943-947

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591319
  • [Journal Article] 子どもの骨・関節疾患-診断と治療2011

    • Author(s)
      大薗恵一
    • Journal Title

      総合臨床

      Volume: 60(10) Pages: 2151-2152

    • Data Source
      KAKENHI-PROJECT-21591319
  • [Journal Article] Kitaoka T, Namba N, Miura K, Kubota T, Ohata Y, Fujiwara M, Hirai H, Yamamoto T, Ozono K.2011

    • Author(s)
      Kitaoka T, Namba N, Miura K, Kubota T, Ohata Y, Fujiwara M, Hirai H, Yamamoto T, Ozono K.
    • Journal Title

      J Bone Miner Metab

      Volume: 29(5) Pages: 598-605

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591319
  • [Journal Article] 主要な生体調節臓器としての骨2011

    • Author(s)
      大薗恵一
    • Journal Title

      生産と技術

      Volume: 63(3) Pages: 77-82

    • Data Source
      KAKENHI-PROJECT-21591319
  • [Journal Article] 小児とビタミン2011

    • Author(s)
      大薗恵一
    • Journal Title

      D. THE BONE

      Volume: 25(3) Pages: 105-110

    • Data Source
      KAKENHI-PROJECT-21591319
  • [Journal Article] カルシウム感知受容体における病態2011

    • Author(s)
      難波範行, 大薗恵一
    • Journal Title

      臨床検査

      Volume: 55(10) Pages: 973-978

    • Data Source
      KAKENHI-PROJECT-21591319
  • [Journal Article] Elevated Bone Turnover in an Infantile Patient with Mucolipidosis II ; No Association with Hyperparathyroidism2011

    • Author(s)
      Otomo T, Yamamoto T, Fujikawa Y, Shimotsuji T, Ozono K.
    • Journal Title

      Clin Pediatr Endocrinol

      Volume: 20(1) Pages: 7-12

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591319
  • [Journal Article] Both FGF23 and extracellular phosphate activate Raf/ MEK/ ERK pathway via FGF receptors in HEK293 cells2010

    • Author(s)
      Yamazaki M, Ozono K, Okada T, Tachikawa K, Kondou H, Ohata Y, Michigami T.
    • Journal Title

      J Cell Biochem

      Volume: 111(5) Pages: 1210-1221

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591319
  • [Journal Article] Signaling of extracellular inorganic phosphate up-regulates cyclin D1 expression in proliferating chondrocytes via the Na+/ Pi cotransporter Pit-1 and Raf/ MEK/ ERK pathway2010

    • Author(s)
      Kimata M, Michigami T, Tachikawa K, Okada T, Koshimizu T, Yamazaki M, Kogo M, Ozono K.
    • Journal Title

      Bone

      Volume: 47(5) Pages: 938-947

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591319
  • [Journal Article] Severe arterial hypertension : a possible complication of McCune-Albright syndrome2009

    • Author(s)
      Ohata Y, Yamamoto T, Ozono K(9番目),(他6名)
    • Journal Title

      Eur J Pediate (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591204
  • [Journal Article] Wnt signaling in bone metabolism.2009

    • Author(s)
      Kubota T, Michigami T, Ozono K.
    • Journal Title

      J Bone Miner Metab

      Volume: 27(3) Pages: 265-271

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591319
  • [Journal Article] Oncogenic nucleoporin CAN/ Nup214 interacts with vitamin D receptor and modulates its function2009

    • Author(s)
      Miyauchi Y, Sakaguchi N, Okada T, Makishima M, Ozono K, Michigami T.
    • Journal Title

      J Cell Biochem

      Volume: 106(6) Pages: 1090-1101

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591319
  • [Journal Article] Causes and Differential Diagnosis of Hypocalcemia - Recommendation Proposed by Expert Panel Supported by Ministry of Health2009

    • Author(s)
      Fukumoto S, Namba N, Ozono K,(他8名)
    • Journal Title

      Labour and Welfare.Japan -Endocr J (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591204
  • [Journal Article] PTH/cAMP/PKA Signaling Facilitates Canonical Wnt Signaling Via Inactivation of Glycogen Synthase Kinase-3βin Osteoblastic saos-2 Cells.Journal of Cellular2008

    • Author(s)
      Suzuki A, Ozono K, Kubota T, (他3名)
    • Journal Title

      Biochemistry 104(1)

      Pages: 304-317

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591204
  • [Journal Article] Clinical usefulness of measurement of fibroblast growth factor 23 (FGF23) in hypophosphatemic patients : proposal of diagnostic criteria using FGF23 measurement2008

    • Author(s)
      Endo I, Fukumoto S, Ozono K,(他8名)
    • Journal Title

      Bone 42(6)

      Pages: 1235-1239

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591204
  • [Journal Article] 低リン血症性疾患の病態と治療-クル病/骨軟化症を含めて-2008

    • Author(s)
      大薗恵一
    • Journal Title

      THE BONE 22(6)

      Pages: 747-751

    • Data Source
      KAKENHI-PROJECT-19591204
  • [Journal Article] Severe mandibuloacral dysplasia caused by novel compound heterozygous ZMPSTE24 mutations in two Japanese siblings2008

    • Author(s)
      Miyoshi Y, Akagi M, Ozono K(14番目),(他11名)
    • Journal Title

      Clin Genet 73(6)

      Pages: 535-544

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591204
  • [Journal Article] Lrp6 hypomorphic mutation affects bone mass through bone resorption in mice and impairs interaction with Mesd2008

    • Author(s)
      Kubota T, Michigami T, Ozono K(10番目),(他7名)
    • Journal Title

      J Bone Miner Res 23(10)

      Pages: 1661-1671

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591204
  • [Journal Article] 低リン血症性疾患の病態と治療-クル病/骨軟化症を含めて-2008

    • Author(s)
      大薗 恵一
    • Journal Title

      THE BONE 22(6)

      Pages: 747-751

    • Data Source
      KAKENHI-PROJECT-19591204
  • [Journal Article] The molecular mechanism underlying Roberts syndrome involves loss of ESCO2 acetyltransferase activity2008

    • Author(s)
      Gordillo M, Vega H, Ozono K(23番目)(他23名)
    • Journal Title

      Hum Mol Genet 17(14)

      Pages: 2172-2180

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591204
  • [Journal Article] Growth hormone stimulates adipogenesis of 3T3-L1 cells through activation of the Stat5A/5B-PPARg pathway.2007

    • Author(s)
      Kawai M, Namba N, Mushiake S, Etani Y, Nishimura R, Makishima M, Ozono K
    • Journal Title

      J Mol Endocrinol. 38(1)

      Pages: 19-34

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591087
  • [Journal Article] Growth hormone stimulates adipogenesis of 3T3-L1 cells through activation of the Stat5A/5B-PPARγ pathway.2007

    • Author(s)
      Kawai M, Namba N, Mushiake S, Etani Y, Nishimura R, Makishima M, Ozono K
    • Journal Title

      J Mol Endocrinol. 38(1)

      Pages: 19-34

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591087
  • [Journal Article] Growth hormone stimulates adipogenesis of 3T3-L1 cells through activation of the Stat5A/5B-PPAR{gamma} pathway.2007

    • Author(s)
      Kawai M, Namba N, Mushiake S, Etani Y, Nishimura R, Makishima M, Ozono K
    • Journal Title

      J Mol Endocrinol. 38(1)

      Pages: 19-34

    • Data Source
      KAKENHI-PROJECT-17591087
  • [Journal Article] Pathological variations in pediatric liver diseases characterized by fatty deposition to the hepatocytes.2007

    • Author(s)
      Mushiake S, Etani Y, Miyoshi Y, Bessho K, Kawamoto K, Ozono K
    • Journal Title

      Hepatology 42(4)suppl

      Pages: 473-473

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591087
  • [Journal Article] Novel mutation of gene coding for glial fibrillary acidic protein in a Japanese patient with Alexander disease2006

    • Author(s)
      Kawai M, Sakai N, Miyake S, Tsukamoto H, Akagi M, Inui K, Mushiake S, Taniike M, Ozono K.
    • Journal Title

      Brain Dev 28(6)

      Pages: 60-62

    • NAID

      10017319316

    • Data Source
      KAKENHI-PROJECT-16591026
  • [Journal Article] Novel mutation of gene coding for glial fibrillary acidic protein in a Jananese patient with Alexander disease2006

    • Author(s)
      Kawai M, Sakai N, Miyake S, Tsukamoto H, Akagi M, Inui K, Mushiake S, Taniike M, Ozono K.
    • Journal Title

      Brain Dev 28(6)

      Pages: 60-62

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591026
  • [Journal Article] Novel mutation of gene coding for glial fibrillary acidic protein in a Japanese patient with Alexander disease2006

    • Author(s)
      Kawai M, Sakai N, Miyake S, Tsukamoto H, Akagi M, Inui K, Mushiake S, Taniike M, Ozono K.
    • Journal Title

      Brain Dev 28.6

      Pages: 60-62

    • NAID

      10017319316

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591026
  • [Journal Article] Characterization of the sensitivity of lymphoblastoid cell lines to various stress agents in Roberts syndrome2006

    • Author(s)
      Gordillo M, Vega H, Sakai N, Tsukamoto H, Ozono K, Inui K
    • Journal Title

      Med J Osaka Univ 49(1-4)

      Pages: 29-41

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591026
  • [Journal Article] Roberts syndrome is caused by mutations in ESCO2, a human homolog of yeast ECO1 that is essential for the establishment of sister chromatid cohesion2005

    • Author(s)
      Vega H, Waisfisz Q, Gordillo M, Sakai N, Yanagihara I, Yamada M, van Gosliga D, Kayserili H, Xu C, Ozono K, Jabs EW, Inui K, Joenje H.
    • Journal Title

      Nat Genet 37.5

      Pages: 468-470

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591026
  • [Journal Article] Pathological variations in pediatric liver diseases characterized by fatty deposition to the hepatocytes.2005

    • Author(s)
      Mushiake S, Etani Y, Miyoshi Y, Bessho K, Kawamoto K, Ozono K
    • Journal Title

      Hepatology. 42(4)(suppl.)

      Pages: 473-473

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591087
  • [Journal Article] Pathological variations in pediatric liver diseases characterized by fatty deposition to the hepatocytes.2005

    • Author(s)
      Mushiake S, Etani Y, Miyoshi Y, Bessho K, Kawamoto K, Ozono K
    • Journal Title

      Hepatology 42(4)(suppl.)

      Pages: 473-473

    • Data Source
      KAKENHI-PROJECT-17591087
  • [Journal Article] Roberts syndrome is caused by mutations in ESCO2, a human homolog of yeast ECO1 that is essential for the establishment of sister chromatid cohesion2005

    • Author(s)
      Vega H, Waisfisz Q, Gordillo M, Sakai N, Yanagihara I, Yamada M, van Gosliga D, Kayserili H, Xu C, Ozono K, Jabs EW, Inui K, Joenie H.
    • Journal Title

      Nat Genet 37(5)

      Pages: 468-470

    • Data Source
      KAKENHI-PROJECT-16591026
  • [Journal Article] Successful stenting for renal artery stenosis in a patient with Alagille syndrome.2005

    • Author(s)
      Hirai H, Santo Y, Kogaki S, Mushiake S, Nakatsuchi Y, Nakajima S, Ozono K.
    • Journal Title

      Pediatric Nephrology 20(6)

      Pages: 831-833

    • Data Source
      KAKENHI-PROJECT-17591087
  • [Journal Article] Roberts syndrome is caused by mutations in ESCO2, a human homolog of yeast ECO1 that is essential for the establishment of sister chromatid cohesion2005

    • Author(s)
      Vega H, Waisfisz Q, Gordillo M, Sakai N, Yanagihara I, Yamada M, van Gosliga D, Kayserili H, Xu C, Ozono K, Jabs EW, Inui K, Joenje H.
    • Journal Title

      Nat Genet 37(5)

      Pages: 468-470

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591026
  • [Journal Article] Characterization of the sensitivity of lymphoblastoid cell lines to various stress agents in Roberts syndrome

    • Author(s)
      Gordillo M, Vega H, Sakai N.Tsukamoto H, Ozono K, Inui K
    • Journal Title

      Med J Osaka Univ in press

    • Data Source
      KAKENHI-PROJECT-16591026
  • [Journal Article] Characterization of the sensitivity of lymphoblastoid cell lines to various stress agents in Roberts syndrome

    • Author(s)
      Gordillo M, Vega H, Sakai N, Tsukamoto H, Ozono K, Inui K
    • Journal Title

      Med J Osaka Univ in press

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591026
  • [Journal Article] Six novel mutations detected in GALC gene in 17 Japanese patients with Krabbe disease and new genotype-phenotype correlation

    • Author(s)
      Xu C, Sakai N, Taniike M, Inui K, Ozono K
    • Journal Title

      J Hum Genet in press

    • NAID

      10017608409

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591026
  • [Journal Article] Six novel mutations detected in GALC gene in 17 Japanese patients with Krabbe disease and new genotype-phenotype correlation

    • Author(s)
      Xu C, Sakai N, Taniike M, Inui, Ozono K
    • Journal Title

      J Hum Genet (in press)

    • NAID

      10017608409

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16591026
  • [Journal Article] Six novel mutations detected in GALC gene in 17 Japanese patients with Krabbe disease and new genotype-phenotype correlation

    • Author(s)
      Xu C, Sakai N, Taniike M, Inui, Ozono K
    • Journal Title

      J Hum Genet in press

    • NAID

      10017608409

    • Data Source
      KAKENHI-PROJECT-16591026
  • [Presentation] 当科XLH患者に対するブロスマブ治療長期効果の検討2023

    • Author(s)
      大幡泰久, 山田知絵子, 中野由佳子, 山本賢一, 武鑓真司, 藤原誠, 北岡太一, 窪田拓生, 大薗恵一
    • Organizer
      第96回日本内分泌学会学術総会
    • Data Source
      KAKENHI-PROJECT-21H02881
  • [Presentation] 本邦における FGF23 関連低リン血症性くる病・骨軟化症患者の臨床像の解析2023

    • Author(s)
      藤原誠, 石見壮史, 山田知絵子, 武鑓真司, 山本賢一, 中野由佳子, 中山尋文, 大幡泰久, 北岡太一, 窪田拓生, 大薗恵一
    • Organizer
      第41回 日本骨代謝学会学術集会
    • Data Source
      KAKENHI-PROJECT-21H02881
  • [Presentation] Clinical Features of FGF23-Related Hypophosphatemic Rickets/Osteomalacia: A Multicenter National Survey in Japan2023

    • Author(s)
      Makoto Fujiwara, Taichi Kitaoka, Yasuhisa Ohata, Hirofumi Nakayama, Yukako Nakano, Kenichi Yamamoto, Hiroyuki Saito, Chieko Yamada, Takeshi Ishimi, Ikumi Ueda, Tatsuya Nakamichi, Rieko Takatani, Masanori Minagawa, Inoue Daisuke, Yasuhiro Takeuchi, Seiji Fukumoto, Takashi Akamizu, Keiichi Ozono, and Takuo Kubota
    • Organizer
      ASBMR 2023 Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02881
  • [Presentation] 骨形成不全症の新規モデルマウス2022

    • Author(s)
      武鑓真司, 大幡泰久, 藤原誠, 北岡太一, 窪田拓生, 大薗恵一
    • Organizer
      第55回 日本小児内分泌学会学術集会
    • Data Source
      KAKENHI-PROJECT-21H02881
  • [Presentation] 小児骨形成不全症におけるビスホスホネート治療および体重は血清スクレロスチン値に影響する2022

    • Author(s)
      藤原誠, 北岡太一, 石見壮史, 山田知絵子, 武鑓真司, 山本賢一, 中野由佳子, 中山尋文, 大幡泰久, 窪田拓生, 大薗恵一
    • Organizer
      第95回 日本内分泌学会学術総会
    • Data Source
      KAKENHI-PROJECT-21H02881
  • [Presentation] Col1a1G643S/+ mouse model of osteogenesis imperfecta2022

    • Author(s)
      Shinji Takeyari, Yasuhisa Ohata, Makoto Fujiwara, Taichi Kitaoka, Takuo Kubota, Keiichi Ozono
    • Organizer
      ASBMR 2022 Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02881
  • [Presentation] Genotype-phenotype analysis, and assessment of the importance of the zinc-binding site in PHEX in Japanese patients with X-linked hypophosphatemic rickets using 3D structure modeling.2021

    • Author(s)
      Ohata Y, Ishihara Y, Takeyari S, Kubota T, Ozono K
    • Organizer
      American Society for Bone and Mineral Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02881
  • [Presentation] 患者由来線維芽細胞、iPS細胞を用いた骨形成不全症の病態解析と4-フェニル酪酸の効果(若手研究奨励賞受賞)2021

    • Author(s)
      武鑓真司, 大幡泰久, 藤原誠, 北岡太一, 窪田拓生, 多賀裕喜, 水野一乗, 大薗恵一.
    • Organizer
      第94回 日本内分泌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18H02780
  • [Presentation] 4-phenylbutyric acid likely improves the quality of extracellular matrix and promotes mineralization in patients with osteogenesis imperfecta-derived cells.2020

    • Author(s)
      Takeyari S, Ohata Y, Fujiwara M, Kitaoka T, Kubota T, Taga Y, Mizuno K, Ozono K.
    • Organizer
      ICCBH VIRTUAL FORUM 2020 Bone Fragility Disorders in Children
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02780
  • [Presentation] Analysis of osteogenesis imperfecta in pathology and the effects of 4-phenylbutyric acid using patient-derived fibroblasts and induced pluripotent stem cells (New Investigator Award)2019

    • Author(s)
      Takeyari S, Ohata Y, Kubota T, Taga Y, Mizuno K, Ozono K.
    • Organizer
      9th International Conference on Children's Bone Health
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02780
  • [Presentation] 患者由来線維芽細胞、iPS細胞を用いた骨形成不全症の病態解析と4-フェニル酪酸の効果2019

    • Author(s)
      武鑓真司,大幡泰久,窪田拓生,多賀祐喜,水野一乘,大薗惠一
    • Organizer
      第51回 日本結合組織学会学術大会
    • Data Source
      KAKENHI-PROJECT-18H02780
  • [Presentation] Analysis of osteogenesis imperfecta in pathology and the effects of 4-phenylbutyric acid using patient-derived fibroblasts and induced pluripotent stem c2019

    • Author(s)
      Shinji Takeyari, Yasuhisa Ohata, Takuo Kubota, Yuki Taga, Kazunori Mizuno, Keiichi Ozono
    • Organizer
      ICCBH 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02780
  • [Presentation] 患者由来線維芽細胞、iPS細胞を用いた骨形成不全症の病態解析と4-フェニル酪酸の効果  (Young Investigator Award)2019

    • Author(s)
      武鑓真司, 大幡泰久, 窪田拓生, 多賀祐喜, 水野一乗, 大薗恵一
    • Organizer
      第51回 日本結合組織学会学術大会
    • Data Source
      KAKENHI-PROJECT-18H02780
  • [Presentation] ターゲットエクソーム解析を用いた日本人骨形成不全患者47名の網羅的遺伝子解析と表現型解析2018

    • Author(s)
      大幡泰久,武鑓真司,中野由佳子,山本賢一,中山尋文,北岡太一,窪田拓生,道上敏美,山本威久,大薗恵一
    • Organizer
      第36回 日本骨代謝学会学術集会
    • Data Source
      KAKENHI-PROJECT-18H02780
  • [Presentation] 患者由来iPS細胞、線維芽細胞を用いた骨形成不全症新規治療薬の探索(最優秀演題賞)2018

    • Author(s)
      武鑓真司,大幡泰久,窪田拓生,多賀祐喜,水野一乘,大薗恵一
    • Organizer
      第52回 日本小児内分泌学会学術集会
    • Data Source
      KAKENHI-PROJECT-18H02780
  • [Presentation] Comprehensive Genetic Analysis by Targeted Next Generation Sequencing and Genotype-phenotype Correlation of 47 Japanese Patients with Osteogenesis Imperfecta2018

    • Author(s)
      Ohata Y, Takeyari S, Kitaoka T, Nakayama H, Varoona Bizaoui, Nakano N, Yamamoto K, Miyata K, Yamamoto K, Kubota T, Yamamoto K, Michigami T, Yamamoto T, Ozono K
    • Organizer
      ASBMR2018 Auual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02780
  • [Presentation] ターゲットエクソーム解析を用いた日本人骨形成不全患者52名の網羅的遺伝子解析と 表現型解析2018

    • Author(s)
      大幡泰久,武鑓真司,中野由佳子,山本賢一,宮田 京,中山尋文 Varoona Bizaoui,北岡太一,窪田拓生,山本勝輔,道上敏美,山本威久,大薗恵一
    • Organizer
      第52回 日本小児内分泌学会学術集会
    • Data Source
      KAKENHI-PROJECT-18H02780
  • [Presentation] 小児科医と小児歯科医で共観している低ホスファターゼ症の5症例2017

    • Author(s)
      大川玲奈, 北岡太一, 窪田拓生, 大薗恵一, 仲野和彦.
    • Organizer
      第34回小児代謝性骨疾患研究会
    • Place of Presentation
      千里ライフサイエンスセンター(大阪府吹田市)
    • Year and Date
      2017-01-21
    • Data Source
      KAKENHI-PROJECT-15K11364
  • [Presentation] 生後1日目よりALP酵素補充を行った周産期重症型低ホスファターゼ症の4年間の経過2017

    • Author(s)
      山村なつみ、道上敏美、一木容子、 白石 淳、北島博之、立川加奈子、大川玲奈、仲野和彦、中野慎也、藤原香緒里、里村憲一、和田和子、大薗恵一、山本勝輔
    • Organizer
      第12回ALPS研究会
    • Data Source
      KAKENHI-PROJECT-15K11364
  • [Presentation] 小児内分泌-骨ミネラル異常症を中心として-2014

    • Author(s)
      大薗恵一
    • Organizer
      第23回 臨床内分泌代謝Update
    • Place of Presentation
      名古屋国際会議場
    • Data Source
      KAKENHI-PROJECT-24390264
  • [Presentation] 成長障害診療の現在と未来2013

    • Author(s)
      大薗恵一
    • Organizer
      第24回 日本小児科医会総会フォーラム
    • Place of Presentation
      大阪市中央公会堂
    • Data Source
      KAKENHI-PROJECT-24390264
  • [Presentation] 骨芽細胞・骨細胞の制御と疾患2013

    • Author(s)
      大薗恵一
    • Organizer
      第57回 日本リウマチ学会総会・学術集会 第22回 国際リウマチシンポジウム
    • Place of Presentation
      国立京都国際会館
    • Data Source
      KAKENHI-PROJECT-24390264
  • [Presentation] 骨系統疾患の基礎と臨床-小児科医の立場から-2012

    • Author(s)
      大薗恵一
    • Organizer
      第28回小児成長研究会
    • Place of Presentation
      霞山会館霞ヶ関コモンゲート(東京都)(招待講演)
    • Year and Date
      2012-07-28
    • Data Source
      KAKENHI-PROJECT-24390264
  • [Presentation] Height determination and chondrocyte development-JSPE/ESPE2012

    • Author(s)
      Ozono K
    • Organizer
      51st Annual Meeting of the European Society for Paediatric Endocrinology
    • Place of Presentation
      The Congress Center Leipzig (Leipzig, Germany)(招待講演)
    • Year and Date
      2012-09-22
    • Data Source
      KAKENHI-PROJECT-24390264
  • [Presentation] 骨系統疾患2012

    • Author(s)
      大薗恵一
    • Organizer
      第30回日本骨代謝学会学術集会
    • Place of Presentation
      京王プラザホテル(東京都)(招待講演)
    • Year and Date
      2012-07-19
    • Data Source
      KAKENHI-PROJECT-24390264
  • [Presentation] 骨系統疾患の新たな治療法2012

    • Author(s)
      大薗恵一
    • Organizer
      第10回 日本胎児治療学会 第5回 胎児骨系統疾患フォーラム併催
    • Place of Presentation
      仙台市情報・産業プラザ(宮城県)(招待講演)
    • Year and Date
      2012-12-02
    • Data Source
      KAKENHI-PROJECT-24390264
  • [Presentation] management of patients with achondroplasia/hypochondroplasia2011

    • Author(s)
      Ozono K
    • Organizer
      Sungkyunkwan University seminar
    • Place of Presentation
      Samsung Medical Center (Korea)(Invited lecture)
    • Year and Date
      2011-11-22
    • Data Source
      KAKENHI-PROJECT-21591319
  • [Presentation] Recent advances in research and clinical practice for rickets2011

    • Author(s)
      Ozono K.
    • Organizer
      the Research Center for Rare Disease(Invited lecture)
    • Place of Presentation
      Seoul National University Children' s Hospital(Korea)
    • Year and Date
      2011-11-23
    • Data Source
      KAKENHI-PROJECT-21591319
  • [Presentation] Recent advances in research and clinical practice for rickets2011

    • Author(s)
      Ozono K
    • Organizer
      the Research Center for Rare Disease
    • Place of Presentation
      Seoul National University Children's Hospital (Korea)(Invited lecture)
    • Year and Date
      2011-11-23
    • Data Source
      KAKENHI-PROJECT-21591319
  • [Presentation] 小児科医が知っておくべき骨系統疾患2011

    • Author(s)
      大薗恵一
    • Organizer
      第23回奈良小児内分泌研究会
    • Place of Presentation
      奈良県立医科大学(奈良)(特別講演)
    • Year and Date
      2011-10-27
    • Data Source
      KAKENHI-PROJECT-21591319
  • [Presentation] 小児科医が知っておくべき骨系統疾患2011

    • Author(s)
      大薗恵一
    • Organizer
      第23回奈良小児内分泌研究会(特別講演)
    • Place of Presentation
      奈良県立医科大学(奈良)
    • Year and Date
      2011-10-27
    • Data Source
      KAKENHI-PROJECT-21591319
  • [Presentation] Osteoporosis and osteopetrosis in the young2011

    • Author(s)
      Ozono K
    • Organizer
      IOF Regionals-2nd Asia-Pacific Osteoporosis and Bone Meeting being held in conjunction with the ANZBMS Annual Scientific Meeting and JSBMR
    • Place of Presentation
      GOLD COAST CONVENTION CENTRE (Australia)
    • Year and Date
      2011-09-08
    • Data Source
      KAKENHI-PROJECT-21591319
  • [Presentation] 周産期のカルシウムリン代謝2011

    • Author(s)
      大薗恵一
    • Organizer
      第19回Bone Research Joint Meeting
    • Place of Presentation
      大阪大学(大阪)
    • Year and Date
      2011-11-08
    • Data Source
      KAKENHI-PROJECT-21591319
  • [Presentation] management of patients with achondroplasia/ hypochondroplasia2011

    • Author(s)
      Ozono K.
    • Organizer
      Sungkyunkwan University seminar(Invited lecture)
    • Place of Presentation
      Samsung Medical Center(Korea)
    • Year and Date
      2011-11-22
    • Data Source
      KAKENHI-PROJECT-21591319
  • [Presentation] Osteoporosis and osteopetrosis in the young2011

    • Author(s)
      Ozono K.
    • Organizer
      IOF Regionals-2nd Asia-Pacific Osteoporosis and Bone Meeting being held in conjunction with the ANZBMS Annual Scientific Meeting and JSBMR
    • Place of Presentation
      GOLD COAST CONVENTION CENTRE(Australia)
    • Year and Date
      2011-09-08
    • Data Source
      KAKENHI-PROJECT-21591319
  • [Presentation] 現代の栄養欠乏としてのビタミンD欠乏2011

    • Author(s)
      大薗恵一
    • Organizer
      日本ビタミン学会第63回大会
    • Place of Presentation
      安田女子大学(広島)
    • Year and Date
      2011-06-04
    • Data Source
      KAKENHI-PROJECT-21591319
  • [Presentation] 骨量を規定する新たな遺伝子LRP6に変異を有するマウスの解析2008

    • Author(s)
      大薗恵一
    • Organizer
      第42回日本小児内分泌学会学術集
    • Place of Presentation
      鳥取
    • Data Source
      KAKENHI-PROJECT-19591204
  • [Presentation] 血清カルシウム(Ca)・リン(P)値の異常とその原因2007

    • Author(s)
      大薗恵一
    • Organizer
      第173回大阪小児科学会
    • Place of Presentation
      大阪市
    • Year and Date
      2007-04-07
    • Data Source
      KAKENHI-PROJECT-19591204
  • [Presentation] 低身長症例における血清NT-proCNP値測定の有用性-成長速度及びGH治療反応性-

    • Author(s)
      窪田拓生,三浦弘司,王薇,北岡太一,大幡泰久,山本景子,藤原誠,橘真紀子,三善陽子,難波範行,大薗恵一
    • Organizer
      第87回 日本内分泌学会学術総会
    • Place of Presentation
      福岡
    • Year and Date
      2014-04-24 – 2014-04-26
    • Data Source
      KAKENHI-PROJECT-24390264
  • [Presentation] 症例をもとに解説するカルシウム代謝異常症Update

    • Author(s)
      大薗恵一
    • Organizer
      第18回 鹿児島県小児内分泌研究会(特別講演)
    • Place of Presentation
      ホテルパレスイン鹿児島4F鳳凰の間
    • Data Source
      KAKENHI-PROJECT-24390264
  • [Presentation] 治療対象となってきた骨系統疾患

    • Author(s)
      大薗恵一
    • Organizer
      第13回 熊本内分泌代謝フォーラム(特別講演)
    • Place of Presentation
      くまもと県民交流館パレア会議室2
    • Invited
    • Data Source
      KAKENHI-PROJECT-24390264
  • [Presentation] 軟骨無形成症の合併症とその治療、先進医療も含めて

    • Author(s)
      大薗恵一
    • Organizer
      第29回 つくしんぼ総会
    • Place of Presentation
      大阪市長居障がい者スポーツセンター
    • Data Source
      KAKENHI-PROJECT-24390264
  • [Presentation] Serum Levels of Amino-terminal Propepride of C-type Natriuretic Peptide may Predict Growth Response to Groeth Hormone Treatment in Patients with Achondroplasia /Hypochondroplasia.

    • Author(s)
      Kubota k,Miura K,Wang W,Yamamoto K,Fujiwara M,Ohata Y,Tachabana M,Kitaoka T,Miyoshi Y,Namba N,Ozono K
    • Organizer
      ASBMR2014
    • Place of Presentation
      アメリカ合衆国,ヒューストン
    • Year and Date
      2014-09-12 – 2014-09-15
    • Data Source
      KAKENHI-PROJECT-24390264
  • 1.  MICHIGAMI Toshimi (00301804)
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    # of Collaborated Products: 4 results
  • 18.  NAKANO Michiyo (30359848)
    # of Collaborated Projects: 1 results
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  • 19.  尾形 悦郎 (70013761)
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    # of Collaborated Products: 0 results
  • 20.  柳澤 純 (50301114)
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    # of Collaborated Products: 0 results
  • 21.  市川 智彦 (20241953)
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  • 22.  名和田 新 (10038820)
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  • 23.  首藤 紘一 (50012612)
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  • 24.  梅園 和彦 (50183752)
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  • 25.  加藤 茂明 (60204468)
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  • 26.  山本 威久 (30231674)
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    # of Collaborated Products: 0 results
  • 27.  仲 周平 (10589774)
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    # of Collaborated Products: 6 results
  • 28.  妻木 範行 (50303938)
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    # of Collaborated Products: 9 results
  • 30.  大幡 泰久 (20805460)
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