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KOIZUMI TOMONOBU  小泉 知展

ORCIDConnect your ORCID iD *help
… Alternative Names

小泉 知展  コイズミ トモノブ

KOIZUMI Tomonobu  小泉 知展

小泉 智展  コイズミ トモノリ

KOIZUMI Tomonori  小泉 知展

小泉 和展  コイズミ カズノブ

Less
Researcher Number 20273097
Other IDs
Affiliation (Current) 2025: 信州大学, 医学部附属病院, 特任教授
Affiliation (based on the past Project Information) *help 2020 – 2022: 信州大学, 学術研究院医学系, 教授
2016 – 2018: 信州大学, 学術研究院医学系, 教授
2013: 信州大学, 医学部, 教授
2008 – 2011: 信州大学, 医学部附属病院, 准教授
2003 – 2004: SHINSHU UNIVERSITY SCHOOL OF MEDICINE, ASSISTANT PROFESSOR, 医学部附属病院, 講師 … More
2003: 信州大学, 医学部付属病院, 講師
2002: SHINSHU UNIVERSITY, ASSISTANT PROFESSOR, 医学部, 講師
2001: SHINSHU UNIV., SCH. OF MED., ASSISTANT PROFESSOR, 医学部・附属病院, 講師
2000: 信州大学, 医学部・付属病院, 助手
1999: University Hospital, Shinshu University, Assistant, 医学部・附属病院, 助手
1997 – 1999: SHINSHU UNIVERSITY HOSPITAL,ASSISTANT, 医学部附属病院, 助手
1997: 信州大学, 医学部・附属病院, 助手 Less
Review Section/Research Field
Principal Investigator
Respiratory organ internal medicine / Respiratory organ internal medicine
Except Principal Investigator
Respiratory organ internal medicine / Basic Section 90110:Biomedical engineering-related / Biomedical engineering/Biomaterial science and engineering / Environmental physiology (including Physical medicine and Nutritional physiology) / Clinical nursing / Respiratory organ internal medicine
Keywords
Principal Investigator
緬羊 / sheep / polymixin B / lung injury / endotoxin / anadamide / ポリミキシンBカラム / 肺損傷 / エンドトキシン / アナンダマイド … More / Goblet cell hyperplasia / TGF-beta / Exhaled nitric oxide / Ascaris-sensitized sheep / Induced sputum / Eosinophil / Airway remodeling / Bronchial asthma / 気道炎症 / ステロイド / アスカリス抗原 / リモデリング / 慢性閉塞性肺疾患 / Tryptace / 呼気-酸化窒素 / 杯細胞過形成 / TGF-β / 呼気一酸化窒素 / アスカリス自然感作綿羊 / 誘発喀痰 / 好酸球 / 気管支リモデリング / 気管支喘息 … More
Except Principal Investigator
肺高血圧 / 高地肺水腫 / Bronchoalveolar lavage / High-altitude pulmonary edema / 気管支肺胞洗浄 / サイトカイン / がん / Endothelial nitric oxide synthase / Genetic polymorphism / Vascular endothelial growth factor / 低酸素換気応答 / 一酸化窒素 / チロシン水酸化酵素 / 内皮型一酸化窒素合成酵素 / 遺伝子多型 / VEGF / 免疫染色 / 肥満細胞 / Acute lung injury / 低酸素 / ヤク / 信号増幅 / 超短パルスレーザー / バイオセンサ / ナノバイオシステム / 生体情報・計測 / 生体生命情報学 / モニタリング / マイクロ・ナノデバイス / 生物・生体工学 / Angiotensin-converting enzyme / Coagulation factor V / Tyrosine hydroxylase / 高地順応 / アンギオテンシン変換酵素 / 健常登山家 / 第V因子 / Tyrosine hvdroxylase / Immunohistochemical staining / Pathology / II型肺胞上皮細胞 / 肺サーファクタント / 硝子膜 / 高知肺水腫 / 頚動脈体 / 病理組織 / Goblet cell metaplasia / Sputum / Epithelial cell / Air trapping / Airwav wall thickness / High-resolution computed tomography ( HRCT ) / Airway remodeling / Bronchial asthma / MMP / Air Trap / 気管支壁肥厚 / 気流閉塞 / 不可逆性 / HRCT / 気道過敏性 / 気道過敏症 / Cl-チャンネル / 気道リモデリング / 喀痰 / 杯細胞 / 粘液産生 / 気道上皮 / 気管支喘息 / Yak / blue sheep / Pika / Adaptation / right ventricular hypertrophy / pulmonary hypertension / high altitude / 右心室肥大 / 高地順応特性 / 概日リズム / 高地適応 / チベットヒツジ / ナキウサギ / Respiratory failure / Shock / Polymyxin B Immobilized Fiber (PMX) / Lung lymph fistula / anesthetized sheep / Endotoxemia / Acute respiratory distress syndrome / ガス交換 / エンドトキシン / PMX-F / F比 / P / 呼吸不全 / ショック / PMX / 肺リンパ瘻 / 麻酔下緬羊 / エンドトキシン血症 / 急性呼吸窮迫症候群 / 急性肺損傷 / Exercise / Pulmonary hypertension / Pulmonary artery remodeling / HLA analysis / Individual difference / 右室肥大 / 低酸素換気応答能 / HLA / 高地 / 肺水腫 / 2,3-DPG / ANP / HLA-typing / 高山病 / 肺動脈圧 / 肺MAC症 / 運動負荷 / 肺動脈リモデリング / HLA解析 / 個体差 / Sheep / Proteinase / Tumor necrosis factor / Interleukin / Endotoxin-induced lung injury / グルタチオン / 気道上皮液 / 蛋白分解酵素阻害剤 / VEGF,VPF / 蛋白分解酵素 / TNF / インターロイキン / エンドトキシン肺損傷 / 緬羊 / 症状管理 / 疼痛緩和 / 看護管理 / アウトカムマネジメント / 看護ケア / 疼痛管理 / がん看護 / 肺小動脈 / 牛 / Rho-kinase / 右心カテーテル法 / 肺高血圧症 / エンドセリン / Rhoキナーゼ / high-altitude pulmonary hypertension(HAPH) / ウシ / 高地適応動物 Less
  • Research Projects

    (13 results)
  • Research Products

    (24 results)
  • Co-Researchers

    (24 People)
  •  Ultra-sensitive and rapid cancer testing technique based on fiber-type amplification

    • Principal Investigator
      Yamaguchi Masaki
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 90110:Biomedical engineering-related
    • Research Institution
      Shinshu University
  •  Visualization of cancer by cytokine coding method and biosensor-array with micro-capsules

    • Principal Investigator
      Yamaguchi Masaki
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biomedical engineering/Biomaterial science and engineering
    • Research Institution
      Shinshu University
  •  Outcomes Management of Oncology Nursing

    • Principal Investigator
      KAMIJO Yuko
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Clinical nursing
    • Research Institution
      Shinshu University
  •  Characteristics of pulmonary circulation in high-altitude active animals-Biomolecular study focusing on the central role of Rho-kinase

    • Principal Investigator
      ISHIZAKI Takeshi
    • Project Period (FY)
      2008 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      University of Fukui
  •  A role of anandamide in the development of acute lung injuryPrincipal Investigator

    • Principal Investigator
      KOIZUMI Tomonobu
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Shinshu University
  •  PATHOPHYSIOLOGICAL MECHANISM AND GENETIC SUSCEPTIBILITY IN HIGH-ALTITUDE ACCLIMATIZATION

    • Principal Investigator
      HANAOKA Masayuki
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      SHINSHU UNIVERSITY SCHOOL OF MEDICINE
  •  PATHOPHYSIOLOGICAL MECHANISM AND INDIVIDUAL SUSCEPTIBILITY IN HIGH-ALTITUDE ILLNESS

    • Principal Investigator
      KUBO Keishi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      SHINSHU UNIVERSITY
  •  PHYSIOLOGICAL CHARACTERISTICS OF HIGH-ALTITUDE ADAPTED ANIMALS

    • Principal Investigator
      SAKAI Akio
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Environmental physiology (including Physical medicine and Nutritional physiology)
    • Research Institution
      SHINSHU UNIVERSITY
  •  MORPHOLOGICAL CHANGES OF AIRWAY REMODELING AND AIRWAY INFLAMMATION IN BRONCHIAL ASTHMA

    • Principal Investigator
      FUJIMOTO Keisaku
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      SHINSHU UNIVERSITY SCHOOL OF MEDICINE
  •  THE MECHANISMS OF AIRWAY REMODELING IN BRONCHIAL ASTHMA.Principal Investigator

    • Principal Investigator
      KOIZUMI Tomonobu
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      SHINSHU UNIVERSITY SCHOOL OF MEDICINE
  •  Direct Hemoperfusion with Polymyxin B Immobilized Fiber (PMX) in Acute Lung Injury Induced by Endotoxemia in Anesthetized Sheep

    • Principal Investigator
      HONDA Takayuki
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Shinshu University
  •  Analysis of Genetic and Constitutional Factors for the Development of High-altitude Pulmonary Edema

    • Principal Investigator
      KUBO Keishi, 小林 俊夫
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Shinshu University
  •  THE ROLE OF INTERLEUKIN,TUMOR NECROSIS FACTOR-ALPHA AND PROTEINASES IN THE DEVELOPMENT OF ACUTE LUNG INJURY IN SHEEP

    • Principal Investigator
      KUBO Keishi
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      SHINSHU UNIVERSITY

All 2021 2019 2018 2017 2016 2004

All Journal Article Presentation Patent

  • [Journal Article] Impact of short-term storage of plasma samples on quantitation of ultra-low levels of interleukin-62021

    • Author(s)
      Yamaguchi Masaki、Koizumi Tomonobu、Sugano Mitsutoshi
    • Journal Title

      Journal of International Medical Research

      Volume: 49 Issue: 11 Pages: 1-7

    • DOI

      10.1177/03000605211056846

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H04514
  • [Journal Article] Plasma cytokine levels and the presence of colorectal cancer2019

    • Author(s)
      Yamaguchi Masaki、Okamura Shin、Yamaji Taiki、Iwasaki Motoki、Tsugane Shoichiro、Shetty Vivek、Koizumi Tomonobu
    • Journal Title

      PLOS ONE

      Volume: 14 Issue: 3 Pages: e0213602-e0213602

    • DOI

      10.1371/journal.pone.0213602

    • NAID

      120007113404

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H03166
  • [Journal Article] Salivary cytokine panel indicative of non-small cell lung cancer2018

    • Author(s)
      Koizumi Tomonobu、Shetty Vivek、Yamaguchi Masaki
    • Journal Title

      Journal of International Medical Research

      Volume: 46 Issue: 9 Pages: 3570-3582

    • DOI

      10.1177/0300060518775563

    • NAID

      120007113405

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H03166
  • [Journal Article] Primary malignant lymphoma in the posterior mediastinum2004

    • Author(s)
      Takamizawa A, Koizumi T 他
    • Journal Title

      Respiration 71

      Pages: 417-420

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590801
  • [Journal Article] Comparison of pulmonary vascular response to endogenous nitric oxide inhibition in sheep and pigs living at 2,300 m2004

    • Author(s)
      Ruan Z, Koizumi T et al.
    • Journal Title

      J Comp Physiol [B] 174

      Pages: 549-555

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590801
  • [Journal Article] Primary malignant lymphoma in the posterior Mediastinum2004

    • Author(s)
      Takamizawa A, Koizumi T et al.
    • Journal Title

      Respiration 71

      Pages: 417-420

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590801
  • [Journal Article] Phase II study of weekly docetaxel combined with cisplatin in patients with advanced non-small-cell lung cancer2004

    • Author(s)
      Tsunoda T, Koizumi T, 他
    • Journal Title

      Cancer Chemother Pharmacol 54

      Pages: 173-177

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590801
  • [Journal Article] Phase II study of weekly docetaxel combined with cisplatin in patients with advanced non-small-cell lung cancer2004

    • Author(s)
      Tsunoda T, Koizumi T, et al.
    • Journal Title

      Cancer Chemother Pharmacol 54

      Pages: 173-177

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590801
  • [Journal Article] Effect of ONO1714, a specific inducible nitric oxide synthase inhibitor, on lung lymph filtration and as exchange during endotoxemia in unanesthetized2004

    • Author(s)
      Koizumi T, 他
    • Journal Title

      Anesthesiology 101

      Pages: 59-65

    • Data Source
      KAKENHI-PROJECT-15590801
  • [Journal Article] Comparison of pulmonary vascular response to endogenous nitric oxide inhibition in sheep and pigs living at 2,300 m2004

    • Author(s)
      Ruan Z, Koizumi T 他
    • Journal Title

      J Comp Physiol [B] 174

      Pages: 549-554

    • Data Source
      KAKENHI-PROJECT-15590801
  • [Journal Article] PTE-607, a cytokine release blocker, attenuates acid aspiration-induced lung injury in rats2004

    • Author(s)
      Jian MY, Koizumi T 他
    • Journal Title

      Eur J Pharmacol 488

      Pages: 231-238

    • Data Source
      KAKENHI-PROJECT-15590801
  • [Journal Article] Effect of ONO1714, a specific inducible nitric oxide synthase inhibitor, on lung lymph filtration and gas exchange during endotoxemia in unanesthetized2004

    • Author(s)
      Koizumi T, 他
    • Journal Title

      Anesthesiology 101

      Pages: 59-65

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590801
  • [Journal Article] Effect of ONO1714, a specific inducible nitric oxide synthase inhibitor, on lung lymph filtration and gas exchange during endotoxemia in unanesthetized sheep2004

    • Author(s)
      Koizumi T, et al.
    • Journal Title

      Anesthesiology 101

      Pages: 59-65

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590801
  • [Journal Article] Contribution of nitric oxide to adaptation of tibetan sheep to high altitude2004

    • Author(s)
      Koizumi T 他
    • Journal Title

      Respir Physiol Neurobiol 140

      Pages: 189-196

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590801
  • [Journal Article] JTE-607, a cytokine release blocker, attenuates acid aspiration-induced lung injury in rats2004

    • Author(s)
      jian MY, Koizumi T 他
    • Journal Title

      Eur J Pharmacol 488

      Pages: 231-238

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590801
  • [Journal Article] Comparison of pulmonary vascular response to endogenous nitric oxide inhibition in sheep and pigs living at 2,300m2004

    • Author(s)
      Ruan Z, Koizumi T 他
    • Journal Title

      J Comp Physiol [B] 174

      Pages: 549-554

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590801
  • [Journal Article] JTE-607, a cytokine release blocker, attenuates acid aspiration-induced lung injury in rats2004

    • Author(s)
      Jian MY, Koizumi T et al.
    • Journal Title

      Eur J Pharmacol 488

      Pages: 231-238

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590801
  • [Journal Article] Contribution of nitric oxide to adaptation of tibetan sheep to high altitude2004

    • Author(s)
      Koizumi T, et al.
    • Journal Title

      Respir Physiol Neurobiol 140

      Pages: 189-196

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590801
  • [Patent] 肺がん進行度合いの評価方法,肺がん進行度合い評価装置,肺がん進行度合い評価プログラム,肺がん進行度合い評価システム及び情報通信端末装置2016

    • Inventor(s)
      山口 昌樹,小泉 知展
    • Industrial Property Rights Holder
      信州大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2016-209657
    • Filing Date
      2016-10-26
    • Data Source
      KAKENHI-PROJECT-16H03166
  • [Patent] 肺がん進行度合いの評価方法,肺がん進行度合い評価装置,肺がん進行度合い評価プログラム,肺がん進行度合い評価システム及び情報通信端末装置2016

    • Inventor(s)
      山口 昌樹,小泉 知展
    • Industrial Property Rights Holder
      信州大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2016
    • Acquisition Date
      2018
    • Data Source
      KAKENHI-PROJECT-16H03166
  • [Patent] 肺がんリスク状態の評価方法,肺がんリスク状態評価装置,肺がんリスク状態評価プログラム,肺がんリスク状態評価システム及び情報通信端末装置2016

    • Inventor(s)
      山口 昌樹,小泉 知展
    • Industrial Property Rights Holder
      信州大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2016-145095
    • Filing Date
      2016-07-25
    • Data Source
      KAKENHI-PROJECT-16H03166
  • [Presentation] 血漿インターロイキン6濃度に与える短時間静置の影響2021

    • Author(s)
      山口 昌樹,小泉 知展,菅野 光俊
    • Organizer
      第60回日本生体医工学会大会
    • Data Source
      KAKENHI-PROJECT-20H04514
  • [Presentation] Clinical Utility of Blood Cytokine Panels for Colon Cancer2017

    • Author(s)
      Shin Okamura, Tomonobu Koizumi, Yuki Nakayama, Vivek Shetty, Masaki Yamaguchi
    • Organizer
      IEEE Healthcare Innovation Point-Of-Care Technologies Conference (HI-POCT 17)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H03166
  • [Presentation] 唾液中サイトカインによる肺がんスクリーニングの臨床的有用性2017

    • Author(s)
      望月 信,小泉 知展,山口 昌樹
    • Organizer
      第26回ライフサポート学会フロンティア講演会
    • Place of Presentation
      芝浦工業大学 (江東区)
    • Year and Date
      2017-03-10
    • Data Source
      KAKENHI-PROJECT-16H03166
  • 1.  KUBO Keishi (80143965)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 0 results
  • 2.  FUJIMOTO Keisaku (70242691)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 3.  HONDA Takayuki (80238815)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 4.  HANAOKA Masayuki (20334899)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  ISHIZAKI Takeshi (80151364)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  SAKAI Akio (70020758)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  SHIBAMOTO Toshishige (90178921)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  KOBAYASHI Toshio (80020775)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  HUJII Tadashige (50020780)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  OTA Masao (50115333)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  Yamaguchi Masaki (50272638)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 6 results
  • 12.  蜂谷 勤 (20303464)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  MATSUKAWA Shigeru (00092809)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  TOGA Hirohisa (90142554)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  AMESHIMA Shingo (60262614)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  KAMIJO Yuko (40530431)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  ICHIKAWA Motoki (60223088)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  SAITHOU Muneo (50167417)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  MATSUZAKI Tetsuya (30167647)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  MATSUMOTO Takaaki (60199875)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  YAMAGUCHI Shinji (00313859)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  松沢 幸範 (40219423)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  山本 洋 (00322131)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  ALMAZ Aldashev
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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