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MIYOSHI Ken  三好 研

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… Alternative Names

三好 研  ミヨシ ケン

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Researcher Number 20274392
Affiliation (based on the past Project Information) *help 2012: 高知大学, 教育研究部医療学系, 助教
2011: Kochi University, 医歯学系, 助教
2009 – 2011: 高知大学, 教育研究部・医療学系, 助教
2008: 高知大学, 教育研究部医療学系, 助教
1997 – 1998: 高知医科大学, 医学部・附属病院, 助手
Review Section/Research Field
Principal Investigator
Dermatology / Dermatology
Except Principal Investigator
Dermatology
Keywords
Principal Investigator
再生学 / 皮膚炎症 / 乾癬 / ゲルシフトアッセイ法 / LDL / NFκB / 血管内皮細胞 / NF_KB / 黄色腫
Except Principal Investigator
Stat3 … More / IL-23 / モデルマウス / Th17 / 乾癬 / IL-17 / IL-22 / バイオロジックス / IL23/Th17 / 表皮角化細胞 / 発癌 / 紫外線 Less
  • Research Projects

    (5 results)
  • Research Products

    (22 results)
  • Co-Researchers

    (7 People)
  •  Investigation of IL-23/Th17 axis in pathogenesis of psoriasis using a mouse model.

    • Principal Investigator
      TAKAISHI Mikiro
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Kochi University
  •  Stat3阻害剤による新規乾癬治療法の開発Principal Investigator

    • Principal Investigator
      三好 研
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Kochi University
  •  The role of Th17 in the pathogenesis of psoriasis

    • Principal Investigator
      NAKAJIMA Kimiko
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Kochi University
  •  Constitutive activation of Stat3 reveals a critical role in UVB-induced epithelial carcinogenesis

    • Principal Investigator
      YOKOGAWA Maki
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Kochi University
  •  黄色腫血管内皮細胞接着分子発現へのNF_KBの関与Principal Investigator

    • Principal Investigator
      三好 研
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Dermatology
    • Research Institution
      高知医科大学

All 2012 2011 2010 2009

All Journal Article Presentation

  • [Journal Article] Attenuation of psoriasis-like skin lesion in a mouse model by topical treatment with indirubin and its derivative E804.2012

    • Author(s)
      Miyoshi K, Takaishi M, Digiovanni J, Sano S.
    • Journal Title

      J Dermatol Sci.

      Volume: 65(1) Issue: 1 Pages: 70-2

    • DOI

      10.1016/j.jdermsci.2011.10.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591242
  • [Journal Article] Stat3 as a therapeutic target for the treatment of psoriasis : a clinical feasibility study with STA-21, a Stat3 inhibitor.2011

    • Author(s)
      Miyoshi K, Takaishi M, Nakajima K, Ikeda M, Kanda T, Tarutani M, Iiyama T, Asao N, DiGiovanni J, Sano S.
    • Journal Title

      J Invest Dermatol.

      Volume: 131 Pages: 108-117

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591242
  • [Journal Article] Stat3 as a Therapeutic Target for the Treatment of Psoriasis :A Clinical Feasibility Study with STA-21, a Stat3 Inhibitor2011

    • Author(s)
      三好研、中島喜美子、高石樹朗、佐野栄紀, 他
    • Journal Title

      Journal of Investigative Dermatology

      Volume: 131 Pages: 108-117

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591244
  • [Journal Article] Distinct roles of IL-23 and IL-17 in the development of psoriasis-like lesion in a mouse model2011

    • Author(s)
      Nakajima K, K. Kanda T, Takaishi M, Miyoshi K, Kamijima R, Tarutani M, Benson M, Elloso MM, Iwakura Y, DiGiovanni J, Sano S
    • Journal Title

      J Immnuol

      Volume: 186 Pages: 4481-9

    • Data Source
      KAKENHI-PROJECT-21591467
  • [Journal Article] Distinct roles of IL-23 and IL-17 in the development of psoriasis-like lesions in a mouse model.2011

    • Author(s)
      Nakajima K, Kanda T, Takaishi M, Shiga T, Miyoshi K, Nakajima H, Kamijima R, Tarutani M, Benson JM, Elloso MM, Gutshall LL, Naso MF, Iwakura Y, DiGiovanni J, Sano S.
    • Journal Title

      J Immunol.

      Volume: 186(7) Issue: 7 Pages: 4481-9

    • DOI

      10.4049/jimmunol.1000148

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591242
  • [Journal Article] Stat3 as a Therapeutic Target for the Treatment of Psoriasis : A Clinical Feasibility Study with STA-21, a Stat3 Inhibitor2011

    • Author(s)
      Miyoshi K, Takaishi M, Nakajima K, Ikeda M、Kanda T, Tarutani M, Iiyama T, Asao N, DiGiovanni J, Sano S
    • Journal Title

      Journal of Investigative Dermatology

      Volume: Vol.131 Issue: 1 Pages: 105-117

    • DOI

      10.1038/jid.2010.255

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591466, KAKENHI-PROJECT-22591242
  • [Journal Article] Distinct roles of IL-23 and IL-17 in the development of psoriasis-like lesion in a mouse model2011

    • Author(s)
      Nakajima K, K.Kand T, Takaishi M, Miyoshi K, Kamijima R, Tarutani M, Benson M, Elloso MM, Iwakura Y, DiGiovanni J, Sano S
    • Journal Title

      J Immnuol

      Volume: 186 Pages: 4481-4489

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591467
  • [Presentation] Distinct roles of IL-23 and IL-17 in the development of psoriasis-like lesion in a mouse model.2010

    • Author(s)
      Nakajima K, Kanda T, Takaishi M, Miyoshi K, Benson JM, Elloso MM, Iwakura Y, DiGiovanni J, Sano S.
    • Organizer
      SID 2010 Annual Meeting
    • Place of Presentation
      Hilton Atlanta Hotel Atlanta, GA
    • Year and Date
      2010-05-05
    • Data Source
      KAKENHI-PROJECT-22591242
  • [Presentation] The possible contribution of IL-22-producing-non-T cells in the development of psoriasis-like lesions in the mouse model2010

    • Author(s)
      Nakajima K, Kanda T, Takaishi M, Miyoshi M, Benson JM, Elloso MM, Iwakura Y, DiGivanni J, Sano S
    • Organizer
      第35回日本研究皮膚科学会
    • Place of Presentation
      和歌山
    • Year and Date
      2010-12-04
    • Data Source
      KAKENHI-PROJECT-21591467
  • [Presentation] Stat3をターゲットとした新規乾癬治療法の開発2010

    • Author(s)
      三好研、中島喜美子、高石樹朗、佐野栄紀
    • Organizer
      第109回日本皮膚科学会総会
    • Place of Presentation
      大阪国際会議場(大阪市)
    • Year and Date
      2010-04-17
    • Data Source
      KAKENHI-PROJECT-22591242
  • [Presentation] Distinct roles of IL-23 and IL-17 in the development of psoriasis-like lesion in a mouse model : anti-IL-6R antibody had no inhibitory effect for the development of lesion2010

    • Author(s)
      Nakajima K, Kanda T, Takaishi M, Miyoshi M, Benson JM, Elloso MM, Iwakura Y, DiGivanni J, Sano S
    • Organizer
      The 14^<th> international congress of immunology
    • Place of Presentation
      Kobe, Japan
    • Year and Date
      2010-08-28
    • Data Source
      KAKENHI-PROJECT-21591467
  • [Presentation] Stat3阻害剤であるSTA-21はヒト正常表皮角化細胞とヒト角化細胞由来株細胞の分化を誘導する2010

    • Author(s)
      高石樹朗、横川真紀、三好研、中島喜美子、John DiGiovanni、佐野栄紀
    • Organizer
      日本組織培養学会 第83回大会
    • Place of Presentation
      岡山大学(岡山市)
    • Year and Date
      2010-05-21
    • Data Source
      KAKENHI-PROJECT-22591242
  • [Presentation] STA-21, a stat3 inhibitor, induces differentiation of normal human epidermal keratinocytes and human, keratinocyte derived cell lines.2010

    • Author(s)
      Takaishi M, Yokogawa M, Miyoshi K, Nakajima K, DiGiovanni J, Sano S.
    • Organizer
      70th SID 2010 Annual Meeting
    • Place of Presentation
      Hilton Atlanta Hotel, Atlanta, U.S.A
    • Year and Date
      2010-05-05
    • Data Source
      KAKENHI-PROJECT-22591242
  • [Presentation] Stat3 as a therapeutic target for the treatment of psoriasis2010

    • Author(s)
      三好研、中島喜美子、高石樹朗、佐野栄紀
    • Organizer
      第109回日本皮膚科学会総会
    • Place of Presentation
      大阪国際会議場(大阪)
    • Year and Date
      2010-04-16
    • Data Source
      KAKENHI-PROJECT-22591244
  • [Presentation] STA-21, a stat3 inhibitor, induces differentiation of normal human epidermal keratinocytes and human keratinocyte derived cell lines.2010

    • Author(s)
      Takaishi M, Yokogawa M, Miyoshi K, Nakajima K, DiGiovanni J, Sano S.
    • Organizer
      SID 2010 Annual Meeting
    • Place of Presentation
      Hilton Atlanta Hotel Atlanta, GA
    • Year and Date
      2010-05-05
    • Data Source
      KAKENHI-PROJECT-22591242
  • [Presentation] 乾癬におけるindirubinの有効性2010

    • Author(s)
      三好研、高石樹朗、佐野栄紀
    • Organizer
      第25回日本乾癬学会学術大会
    • Place of Presentation
      宇部全日空ホテル(宇部市)
    • Year and Date
      2010-09-03
    • Data Source
      KAKENHI-PROJECT-22591242
  • [Presentation] Distinct roles of IL-23 and IL-17 in the development of psoriasis-like lesion in a mouse model2010

    • Author(s)
      Nakajima K, Kanda T, Takaishi M, Miyoshi M, Benson JM, Elloso MM, Iwakura Y, DiGivanni J, Sano S
    • Organizer
      The 70^<th> SID annual meeting
    • Place of Presentation
      Atlanta, USA
    • Year and Date
      2010-05-05
    • Data Source
      KAKENHI-PROJECT-21591467
  • [Presentation] Possible contribution of IL-22-producing non-T cells to the development of psoriasis-like lesion in a mouse model.2010

    • Author(s)
      Nakajima K, Singa S, Kanda T, Takaishi M, Miyoshi K, Sano S.
    • Organizer
      日本研究皮膚科学会第35回年次学術大会
    • Place of Presentation
      和歌山県立文化会館(和歌山市)
    • Year and Date
      2010-12-04
    • Data Source
      KAKENHI-PROJECT-22591242
  • [Presentation] The crosstalk between IL-17, IL-22 and keratinocytes in development of psoriasis-like lesions in a mouse model2010

    • Author(s)
      Nakajima K, Tateo Shiga, Mikiro Takaishi, Ken Miyoshi, Shigetoshi Sano
    • Organizer
      第24回表皮細胞研究会
    • Place of Presentation
      高知
    • Year and Date
      2010-10-09
    • Data Source
      KAKENHI-PROJECT-21591467
  • [Presentation] Distinct roles of IL-23 and IL-17 in the development of psoriasis-like lesion in a mouse model2010

    • Author(s)
      Nakajima K. Kanda T, Takaishi M, Miyoshi K, Benson JM, Elloso MM, Gutshall LL, Naso MF, Iwakura Y, DiGiovanni J, Sano S.
    • Organizer
      14th International congress of immunology
    • Place of Presentation
      神戸ポートピアホテル(神戸市)
    • Year and Date
      2010-08-28
    • Data Source
      KAKENHI-PROJECT-22591242
  • [Presentation] 乾癬モデルマウスにおけるTh17の関与について2009

    • Author(s)
      中島喜美子, 高石樹朗, 三好研, 佐野栄紀
    • Organizer
      第24回日本乾癬学会学術大会
    • Place of Presentation
      東海大校友会館(東京)
    • Year and Date
      2009-09-04
    • Data Source
      KAKENHI-PROJECT-21591467
  • [Presentation] 乾癬モデルマウスにおけるTh17の関与について2009

    • Author(s)
      中島喜美子,高石樹朗,三好研,佐野栄紀
    • Organizer
      第24回日本乾癬学会
    • Place of Presentation
      東京
    • Year and Date
      2009-09-04
    • Data Source
      KAKENHI-PROJECT-21591467
  • 1.  SANO Shigetoshi (80273621)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 22 results
  • 2.  TAKAISHI Mikiro (10303223)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 21 results
  • 3.  NAKAJIMA Kimiko (20403892)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 19 results
  • 4.  YOKOGAWA Maki (40346721)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  TERAISHI Mika (40437736)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  SHIGA Takeo (70444768)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  IKEDA Mitsunori (70212785)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results

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