MIYOSHI Ken 三好研

… Alternative Names

三好研ミヨシケン

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Researcher Number	20274392
Affiliation (based on the past Project Information) *help	2012: 高知大学, 教育研究部医療学系, 助教 2011: Kochi University, 医歯学系, 助教 2009 – 2011: 高知大学, 教育研究部・医療学系, 助教 2008: 高知大学, 教育研究部医療学系, 助教 1997 – 1998: 高知医科大学, 医学部・附属病院, 助手
Review Section/Research Field	Principal Investigator Dermatology / Dermatology Except Principal Investigator Dermatology
Keywords	Principal Investigator 再生学 / 皮膚炎症 / 乾癬 / ゲルシフトアッセイ法 / LDL / NFκB / 血管内皮細胞 / NF_KB / 黄色腫 Except Principal Investigator Stat3 … More / IL-23 / モデルマウス / Th17 / 乾癬 / IL-17 / IL-22 / バイオロジックス / IL23/Th17 / 表皮角化細胞 / 発癌 / 紫外線 Less

Investigation of IL-23/Th17 axis in pathogenesis of psoriasis using a mouse model.
- Principal Investigator
  
  TAKAISHI Mikiro
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Kochi University
Stat3阻害剤による新規乾癬治療法の開発Principal Investigator
- Principal Investigator
  
  三好研
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Kochi University
The role of Th17 in the pathogenesis of psoriasis
- Principal Investigator
  
  NAKAJIMA Kimiko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Kochi University
Constitutive activation of Stat3 reveals a critical role in UVB-induced epithelial carcinogenesis
- Principal Investigator
  
  YOKOGAWA Maki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Kochi University
黄色腫血管内皮細胞接着分子発現へのNF_KBの関与Principal Investigator
- Principal Investigator
  
  三好研
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Dermatology
- Research Institution
  高知医科大学

All 2012 2011 2010 2009

All Journal Article Presentation

[Journal Article] Attenuation of psoriasis-like skin lesion in a mouse model by topical treatment with indirubin and its derivative E804.2012
- Author(s)
  Miyoshi K, Takaishi M, Digiovanni J, Sano S.
- Journal Title
  
  J Dermatol Sci.
  
  Volume: 65(1) Issue: 1 Pages: 70-2
- DOI
  10.1016/j.jdermsci.2011.10.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591242
[Journal Article] Stat3 as a therapeutic target for the treatment of psoriasis : a clinical feasibility study with STA-21, a Stat3 inhibitor.2011
- Author(s)
  Miyoshi K, Takaishi M, Nakajima K, Ikeda M, Kanda T, Tarutani M, Iiyama T, Asao N, DiGiovanni J, Sano S.
- Journal Title
  
  J Invest Dermatol.
  
  Volume: 131 Pages: 108-117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591242
[Journal Article] Stat3 as a Therapeutic Target for the Treatment of Psoriasis :A Clinical Feasibility Study with STA-21, a Stat3 Inhibitor2011
- Author(s)
  三好研、中島喜美子、高石樹朗、佐野栄紀, 他
- Journal Title
  
  Journal of Investigative Dermatology
  
  Volume: 131 Pages: 108-117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591244
[Journal Article] Distinct roles of IL-23 and IL-17 in the development of psoriasis-like lesion in a mouse model2011
- Author(s)
  Nakajima K, K. Kanda T, Takaishi M, Miyoshi K, Kamijima R, Tarutani M, Benson M, Elloso MM, Iwakura Y, DiGiovanni J, Sano S
- Journal Title
  
  J Immnuol
  
  Volume: 186 Pages: 4481-9
- Data Source
  KAKENHI-PROJECT-21591467
[Journal Article] Distinct roles of IL-23 and IL-17 in the development of psoriasis-like lesions in a mouse model.2011
- Author(s)
  Nakajima K, Kanda T, Takaishi M, Shiga T, Miyoshi K, Nakajima H, Kamijima R, Tarutani M, Benson JM, Elloso MM, Gutshall LL, Naso MF, Iwakura Y, DiGiovanni J, Sano S.
- Journal Title
  
  J Immunol.
  
  Volume: 186(7) Issue: 7 Pages: 4481-9
- DOI
  10.4049/jimmunol.1000148
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591242
[Journal Article] Stat3 as a Therapeutic Target for the Treatment of Psoriasis : A Clinical Feasibility Study with STA-21, a Stat3 Inhibitor2011
- Author(s)
  Miyoshi K, Takaishi M, Nakajima K, Ikeda M、Kanda T, Tarutani M, Iiyama T, Asao N, DiGiovanni J, Sano S
- Journal Title
  
  Journal of Investigative Dermatology
  
  Volume: Vol.131 Issue: 1 Pages: 105-117
- DOI
  10.1038/jid.2010.255
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591466, KAKENHI-PROJECT-22591242
[Journal Article] Distinct roles of IL-23 and IL-17 in the development of psoriasis-like lesion in a mouse model2011
- Author(s)
  Nakajima K, K.Kand T, Takaishi M, Miyoshi K, Kamijima R, Tarutani M, Benson M, Elloso MM, Iwakura Y, DiGiovanni J, Sano S
- Journal Title
  
  J Immnuol
  
  Volume: 186 Pages: 4481-4489
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591467
[Presentation] Distinct roles of IL-23 and IL-17 in the development of psoriasis-like lesion in a mouse model.2010
- Author(s)
  Nakajima K, Kanda T, Takaishi M, Miyoshi K, Benson JM, Elloso MM, Iwakura Y, DiGiovanni J, Sano S.
- Organizer
  SID 2010 Annual Meeting
- Place of Presentation
  Hilton Atlanta Hotel Atlanta, GA
- Year and Date
  2010-05-05
- Data Source
  KAKENHI-PROJECT-22591242
[Presentation] The possible contribution of IL-22-producing-non-T cells in the development of psoriasis-like lesions in the mouse model2010
- Author(s)
  Nakajima K, Kanda T, Takaishi M, Miyoshi M, Benson JM, Elloso MM, Iwakura Y, DiGivanni J, Sano S
- Organizer
  第35回日本研究皮膚科学会
- Place of Presentation
  和歌山
- Year and Date
  2010-12-04
- Data Source
  KAKENHI-PROJECT-21591467
[Presentation] Stat3をターゲットとした新規乾癬治療法の開発2010
- Author(s)
  三好研、中島喜美子、高石樹朗、佐野栄紀
- Organizer
  第109回日本皮膚科学会総会
- Place of Presentation
  大阪国際会議場(大阪市)
- Year and Date
  2010-04-17
- Data Source
  KAKENHI-PROJECT-22591242
[Presentation] Distinct roles of IL-23 and IL-17 in the development of psoriasis-like lesion in a mouse model : anti-IL-6R antibody had no inhibitory effect for the development of lesion2010
- Author(s)
  Nakajima K, Kanda T, Takaishi M, Miyoshi M, Benson JM, Elloso MM, Iwakura Y, DiGivanni J, Sano S
- Organizer
  The 14^<th> international congress of immunology
- Place of Presentation
  Kobe, Japan
- Year and Date
  2010-08-28
- Data Source
  KAKENHI-PROJECT-21591467
[Presentation] Stat3阻害剤であるSTA-21はヒト正常表皮角化細胞とヒト角化細胞由来株細胞の分化を誘導する2010
- Author(s)
  高石樹朗、横川真紀、三好研、中島喜美子、John DiGiovanni、佐野栄紀
- Organizer
  日本組織培養学会第83回大会
- Place of Presentation
  岡山大学(岡山市)
- Year and Date
  2010-05-21
- Data Source
  KAKENHI-PROJECT-22591242
[Presentation] STA-21, a stat3 inhibitor, induces differentiation of normal human epidermal keratinocytes and human, keratinocyte derived cell lines.2010
- Author(s)
  Takaishi M, Yokogawa M, Miyoshi K, Nakajima K, DiGiovanni J, Sano S.
- Organizer
  70th SID 2010 Annual Meeting
- Place of Presentation
  Hilton Atlanta Hotel, Atlanta, U.S.A
- Year and Date
  2010-05-05
- Data Source
  KAKENHI-PROJECT-22591242
[Presentation] Stat3 as a therapeutic target for the treatment of psoriasis2010
- Author(s)
  三好研、中島喜美子、高石樹朗、佐野栄紀
- Organizer
  第109回日本皮膚科学会総会
- Place of Presentation
  大阪国際会議場(大阪)
- Year and Date
  2010-04-16
- Data Source
  KAKENHI-PROJECT-22591244
[Presentation] STA-21, a stat3 inhibitor, induces differentiation of normal human epidermal keratinocytes and human keratinocyte derived cell lines.2010
- Author(s)
  Takaishi M, Yokogawa M, Miyoshi K, Nakajima K, DiGiovanni J, Sano S.
- Organizer
  SID 2010 Annual Meeting
- Place of Presentation
  Hilton Atlanta Hotel Atlanta, GA
- Year and Date
  2010-05-05
- Data Source
  KAKENHI-PROJECT-22591242
[Presentation] 乾癬におけるindirubinの有効性2010
- Author(s)
  三好研、高石樹朗、佐野栄紀
- Organizer
  第25回日本乾癬学会学術大会
- Place of Presentation
  宇部全日空ホテル(宇部市)
- Year and Date
  2010-09-03
- Data Source
  KAKENHI-PROJECT-22591242
[Presentation] Distinct roles of IL-23 and IL-17 in the development of psoriasis-like lesion in a mouse model2010
- Author(s)
  Nakajima K, Kanda T, Takaishi M, Miyoshi M, Benson JM, Elloso MM, Iwakura Y, DiGivanni J, Sano S
- Organizer
  The 70^<th> SID annual meeting
- Place of Presentation
  Atlanta, USA
- Year and Date
  2010-05-05
- Data Source
  KAKENHI-PROJECT-21591467
[Presentation] Possible contribution of IL-22-producing non-T cells to the development of psoriasis-like lesion in a mouse model.2010
- Author(s)
  Nakajima K, Singa S, Kanda T, Takaishi M, Miyoshi K, Sano S.
- Organizer
  日本研究皮膚科学会第35回年次学術大会
- Place of Presentation
  和歌山県立文化会館(和歌山市)
- Year and Date
  2010-12-04
- Data Source
  KAKENHI-PROJECT-22591242
[Presentation] The crosstalk between IL-17, IL-22 and keratinocytes in development of psoriasis-like lesions in a mouse model2010
- Author(s)
  Nakajima K, Tateo Shiga, Mikiro Takaishi, Ken Miyoshi, Shigetoshi Sano
- Organizer
  第24回表皮細胞研究会
- Place of Presentation
  高知
- Year and Date
  2010-10-09
- Data Source
  KAKENHI-PROJECT-21591467
[Presentation] Distinct roles of IL-23 and IL-17 in the development of psoriasis-like lesion in a mouse model2010
- Author(s)
  Nakajima K. Kanda T, Takaishi M, Miyoshi K, Benson JM, Elloso MM, Gutshall LL, Naso MF, Iwakura Y, DiGiovanni J, Sano S.
- Organizer
  14th International congress of immunology
- Place of Presentation
  神戸ポートピアホテル(神戸市)
- Year and Date
  2010-08-28
- Data Source
  KAKENHI-PROJECT-22591242
[Presentation] 乾癬モデルマウスにおけるTh17の関与について2009
- Author(s)
  中島喜美子, 高石樹朗, 三好研, 佐野栄紀
- Organizer
  第24回日本乾癬学会学術大会
- Place of Presentation
  東海大校友会館(東京)
- Year and Date
  2009-09-04
- Data Source
  KAKENHI-PROJECT-21591467
[Presentation] 乾癬モデルマウスにおけるTh17の関与について2009
- Author(s)
  中島喜美子,高石樹朗,三好研,佐野栄紀
- Organizer
  第24回日本乾癬学会
- Place of Presentation
  東京
- Year and Date
  2009-09-04
- Data Source
  KAKENHI-PROJECT-21591467

1. SANO Shigetoshi (80273621)

# of Collaborated Projects: 4 results

# of Collaborated Products: 22 results
2. TAKAISHI Mikiro (10303223)

# of Collaborated Projects: 4 results

# of Collaborated Products: 21 results
3. NAKAJIMA Kimiko (20403892)

# of Collaborated Projects: 3 results

# of Collaborated Products: 19 results
4. YOKOGAWA Maki (40346721)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. TERAISHI Mika (40437736)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. SHIGA Takeo (70444768)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. IKEDA Mitsunori (70212785)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

MIYOSHI Ken 三好 研

三好 研 ミヨシ ケン

Research Projects

Research Products

Co-Researchers

Investigation of IL-23/Th17 axis in pathogenesis of psoriasis using a mouse model.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Stat3阻害剤による新規乾癬治療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of Th17 in the pathogenesis of psoriasis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Constitutive activation of Stat3 reveals a critical role in UVB-induced epithelial carcinogenesis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

黄色腫血管内皮細胞接着分子発現へのNF_KBの関与Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Attenuation of psoriasis-like skin lesion in a mouse model by topical treatment with indirubin and its derivative E804.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Stat3 as a therapeutic target for the treatment of psoriasis : a clinical feasibility study with STA-21, a Stat3 inhibitor.2011

Author(s)

Journal Title

Data Source

[Journal Article] Stat3 as a Therapeutic Target for the Treatment of Psoriasis :A Clinical Feasibility Study with STA-21, a Stat3 Inhibitor2011

Author(s)

Journal Title

Data Source

[Journal Article] Distinct roles of IL-23 and IL-17 in the development of psoriasis-like lesion in a mouse model2011

Author(s)

Journal Title

Data Source

[Journal Article] Distinct roles of IL-23 and IL-17 in the development of psoriasis-like lesions in a mouse model.2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Stat3 as a Therapeutic Target for the Treatment of Psoriasis : A Clinical Feasibility Study with STA-21, a Stat3 Inhibitor2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Distinct roles of IL-23 and IL-17 in the development of psoriasis-like lesion in a mouse model2011

Author(s)

Journal Title

Data Source

[Presentation] Distinct roles of IL-23 and IL-17 in the development of psoriasis-like lesion in a mouse model.2010

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] The possible contribution of IL-22-producing-non-T cells in the development of psoriasis-like lesions in the mouse model2010

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Stat3をターゲットとした新規乾癬治療法の開発2010

Author(s)

MIYOSHI Ken 三好研

三好研ミヨシケン