SUMITA Kousuke 角田恒輔

Researcher Number	20281454
Affiliation (based on the past Project Information) *help	1998 – 2002: 愛媛大学, 医学部, 助手 1998: 愛媛大学, 医学部, 教授 1996 – 1997: 聖マリアンナ医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator 内科学一般 Except Principal Investigator Experimental pathology / Biological Sciences / Immunology / 内科学一般 / Bacteriology (including Mycology)
Keywords	Principal Investigator 細胞内刺激伝達系 / チロシンキナーゼ / アンチセンスDNA / Th1型T細胞 / Th1 / IL-12 / Gene Targeting / Txk / GST融合蛋白 / 細胞内刺激伝達 … More / アンチセンスODN / Th2 / T細胞 / インターフェロン-γ … More Except Principal Investigator リステリア菌 / サイトカイン / T細胞サブセット / Listeria monocytogenes / マクロファージ機能 / IRF-1 / IL-12p40 / 細胞死 / 自然免疫 / 獲得免疫 / Th2 / Th1 / cytokine / マクロファージ / マラリア感染 / IFNγ産生細胞 / IL-12p40遺伝子 / innate immunity / IRF-1遺伝子 / マラリア / 遺伝子発現抑制 / MHCクラスI分子 / CD47 / 細胞骨格 / モノクローナル抗体 / 免疫学 / 細菌 / 微生物 / 感染症 / アレルギー・喘息 / 宿主免疫応答 / DNAワクチン / 遺伝子治療 / 遺伝子操作 / アレルギー / アナジー / アレルゲン / 喘息 / anergy / allergen / asthma / 部分放射線照射 / 免疫寛容 / MHC分子 / 多能性幹細胞 / fractionated irradiation / immunological tolerance / cell death / MHC molecules / pluripotent stem cells / IL-12遺伝子 / 樹状細胞 / 感染免疫 / IL-12 gene / macrophage / dendritic cell / Th1細胞 / IgE産生 / リステリア感染 / マウスマクロファージ / Th1ダイプサイトカイン応答 / cDNAサブトラクト / cDNA-RDA法 / シグナルシークエンストラップ / Th1誘導因子 / Macrophage / IgE production / Innate immunity / Adaptive immunity / Cytokines / T cell subsets Less

細胞内寄生性細菌の獲得免疫活性化の分子機構の解明
- Principal Investigator
  
  浅野喜博
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Ehime University
細胞内寄生性細菌を用いた特異的細胞内ドラッグデリバリー法の開発とワクチンへの応用
- Principal Investigator
  
  浅野喜博
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Immunology
- Research Institution
  Ehime University
Linkage between innate immunity and adaptive immunity during pahogen infection
- Principal Investigator
  
  ASANO Yoshihiro
- Project Period (FY)
  2002 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Ehime University
細胞内寄生性細菌の獲得免疫活性化の分子機構の解明
- Principal Investigator
  
  浅野喜博
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Ehime University
Cloning of the Th1 inducing factor from Listeria infected macrophage
- Principal Investigator
  
  KANOH Makoto
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Ehime University
細胞死誘導の第3の経路の解明
- Principal Investigator
  
  浅野喜博
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Experimental pathology
- Research Institution
  Ehime University
マラリア感染に伴う免疫病態異常の解析とその制御法の検討
- Principal Investigator
  
  浅野喜博
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Ehime University
マラリア感染に伴う免疫異常の解析とその制御法の検討
- Principal Investigator
  
  ASANO Yoshihiro
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Ehime University
The 2nd pathway of T cell subset differentiation induced by pathogenic infection
- Principal Investigator
  
  ASANO Yoshihiro
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Immunology
- Research Institution
  EHIME UNIVERSITY
新しい蛋白チロシンキナーゼTxkのヒトTh1型ヘルパーT細胞における役割Principal Investigator
- Principal Investigator
  
  角田恒輔
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  内科学一般
- Research Institution
  Ehime University
  St. Marianna University School of Medicine
Regulation of allergic inflammation by the induction T cell anergy
- Principal Investigator
  
  YAMASHITA Naomi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  St.Marianna University
MOLECULAR MECHANISM OF THE THIRD TYPE OF CELL DEATH AND ITS APPLICATION FOR SPECIFIC IMMUNOSUPPRESSIVE THERAPY
- Principal Investigator
  
  ASANO Yoshihiro
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  内科学一般
- Research Institution
  EHIME UNIVERSITY
RA由来B型滑膜細胞へのオリゴヌクレオチド導入による転写因子活性抑制効果の検討Principal Investigator
- Principal Investigator
  
  角田恒輔
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  内科学一般
- Research Institution
  St. Marianna University School of Medicine

All 2003 2002

All Journal Article

[Journal Article] Preparation and characterization of recombinant marine p65/L-plastin expressed in E.coli and high-titer antibodies against the protein.2003
- Author(s)
  Shinomiya H, Nagai K, Hirata H, Kobayashi N, Hasegawa H, Liu F, Sumita K, Asano Y
- Journal Title
  
  Biosci.Biotechnol.Biochem. 67
  
  Pages: 1368-1375
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207012
[Journal Article] Identification of IFN regulatory factor-binding site in IL-12 p40 gene promoter.2003
- Author(s)
  Maruyama S, Sumita K, Shen H, Kanoh M, Xu X, Sato M, Matsumoto M, Shinomiya H, Asano Y
- Journal Title
  
  J.Immunol. 170
  
  Pages: 997-1001
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207012
[Journal Article] A two-step model of T cell subset commitment. Antigen-independent commitment of T cells before encountering nominal antigen during pathogenic infections.2002
- Author(s)
  Kanoh M, Uetani A, Sakan H, Maruyama S, Liu F, Sumita K, Asano Y
- Journal Title
  
  Int.Immunol. 14
  
  Pages: 567-575
- NAID
  10013882281
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207012

1. ASANO Yoshihiro (70114353)

# of Collaborated Projects: 10 results

# of Collaborated Products: 3 results
2. KANOH Makoto (10116923)

# of Collaborated Projects: 7 results

# of Collaborated Products: 2 results
3. SHINOMIYA Hirota (80162618)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
4. MATSUMOTO Akira (90363233)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. YAMASHITA Naomi (20239974)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. MARUYAMA Saho (10301326)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

SUMITA Kousuke 角田 恒輔

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新しい蛋白チロシンキナーゼTxkのヒトTh1型ヘルパーT細胞における役割Principal Investigator

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RA由来B型滑膜細胞へのオリゴヌクレオチド導入による転写因子活性抑制効果の検討Principal Investigator

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[Journal Article] Preparation and characterization of recombinant marine p65/L-plastin expressed in E.coli and high-titer antibodies against the protein.2003

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[Journal Article] Identification of IFN regulatory factor-binding site in IL-12 p40 gene promoter.2003

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[Journal Article] A two-step model of T cell subset commitment. Antigen-independent commitment of T cells before encountering nominal antigen during pathogenic infections.2002

SUMITA Kousuke 角田恒輔