Asou Teijiro 麻生悌二郎

… Alternative Names

麻生悌二郎アソウテイジロウ

ASO Teijiro 麻生悌二郎

TEIJIRO Aso 麻生悌二郎

麻生悌次郎アソウテイジロウ

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Researcher Number	20291289
Other IDs
External Links
Affiliation (Current)	2022: 高知大学, 教育研究部医療学系基礎医学部門, 教授
Affiliation (based on the past Project Information) *help	2022: 高知大学, 教育研究部医療学系基礎医学部門, 教授 2016 – 2020: 高知大学, 教育研究部医療学系基礎医学部門, 教授 2012 – 2015: 高知大学, 教育研究部医療学系, 教授 2009 – 2011: Kochi University, 教育研究部・医療学系, 教授 2003 – 2007: Kochi Universith, school of medicine, Professor, 医学部, 教授 … More 2001 – 2002: 高知医科大学, 医学部, 教授 2000: (財)癌研究会, 癌研究所・ウイルス腫瘍部, 研究員 2000: Cancer Research Institue, Investigator, 癌研究会研究所, 研究員 1998: 筑波大, 応用生物化学系, 講師 1997: 筑波大学, 先端学際領域センター, 講師 1997: 筑波大学, 応用生物化学系, 講師 Less
Review Section/Research Field	Principal Investigator Biological Sciences / General medical chemistry / Pathological medical chemistry / Basic Section 49010:Pathological biochemistry-related / Structural biochemistry Except Principal Investigator Human genetics / Urology / Urology
Keywords	Principal Investigator RNAポリメラーゼII / 転写伸長 / Elongin / エロンガン / VHL癌抑制遺伝子 / 散発性腎癌 / VHL癌抑制蛋白 / ユビキチンリガーゼ / ES細胞 / ジーンターゲティング … More / p53 / 転写伸長因子 / von Hippel-Lindau病 / 分化 / アポトーシス / p38 MAPK / ノックアウトマウス / 基本転写因子 / 腎癌 / 細胞老化 / シグナル伝達 / 細胞早期老化 / 発現制御 / ストレス / 遺伝子発現 / RNA polymerase II / アルツハイマー病 / カルシウム / カルモデュリン / リカバリン / 多次元NMR / 溶液構造 / NMR / 立体構造 / von Hippel-Liadun病 / Von Hippel-Lindau病 / 癌 / 遺伝子 / 老化 / ストレス応答 / RANポリメラーゼII / 神経分化 / 神経堤 / RNA sequence / ChIP / 遺伝子ノックアウト / Transcription elongation / VHL tumor suppressor gene / Gene targeting / ES cell / 低酸素誘導 / Rpb1 / ubiquitin / ubiquitin ligase / DNA damage / transcription elongation / RNA nolvmerase II / Vcellular senescence / apoptosis / 938 MAPK / hypoxic response / CSB / DNA傷害 / 胚様体 / レチノイン酸 / FRET / small nuclear RNA / non-coding RNA / 認知症 / NRBP1 / BRI2/ITM2 / BRI3/ITM2C / Cullin-RING ligase / BRI2/ITM2B / BRI2 / BRI3 / Cullin RING ligase / Cullin / 認知症治療薬 / 中分子創薬 / タンパク質間相互作用 / BRI2/BRI3 / NRBP1-ユビキチンリガーゼ … More Except Principal Investigator VEGF / MIRC9 / Hypoxia Inducible Factor / TFIIF / 転写伸長 / エロンガン / 転写制御 / Transcriptional elongation / Elongin / 癌抑制遺伝子 / 遺伝子メチル化 / ヒト腎細胞癌 / VHL遺伝子 / VHL / HOXB13 / HIG2 / RAP743極構造 / HIV Tat作用 / 転写リサイクリング / 精巣特異的A2 / エロンガン遺伝子ターゲッテイング / RNAポリメラーゼII / 組織特異的因子 / 開始型 / 伸長型 / トリプシン分解 / 組織特異的エロンガン / p32 / p30 / RNAポリメラーゼIIホロ酵素 / Tripartite structure of RAP74 / HIV-Tat / Transcriptional recycling / Testis-specific A2 / Gene targeting of elongin / エロンガンAノックアウト / 増殖阻害 / 多倍体染色体 / エロンガンファミリー / エロンガンA3 / エロンガンBC活性化 / 転写伸長因子 / 伸長因子活性制御 / 伸長因子ノックアウト / 増殖障害 / 伸長因子病 / ELLホモログ / ES細胞 / 増殖低下 / Elongin A knock-out / Growth arrest / Hypemuclear cells / Elongin Agene family / Elongin A3 / Activation by BC / メチル化 / CpG island methylator phenotype / Ubiquitin liagase / tumor suppressor gene / methylation / renal cell carcinoma / VHL gene / Methylation / Autocline Less

Development of an innovative anti-Alzheimer drug that selectively inhibits the ubiquitination of BRI2 and BRI3Principal Investigator
- Principal Investigator
  
  麻生悌二郎
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Kochi University
Basic study for development of novel anti-dementia drug which selectively targets BRI2/3-ubiquitin ligasePrincipal Investigator
- Principal Investigator
  
  Aso Teijiro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Kochi University
Identification of Elongin A target genes and clarification of the mechanisms governing conversion of the Elongin complex from its elongation factor to its ubiquitin ligase formPrincipal Investigator
- Principal Investigator
  
  Aso Teijiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Kochi University
In vivo role of transcriptional elongation/ubiquitin ligase factor ElonginPrincipal Investigator
- Principal Investigator
  
  ASO Teijiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Kochi University
Role and mechanism of action of mammalian Elongin A in the stress responsePrincipal Investigator
- Principal Investigator
  
  ASO Teijiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Kochi University
転写伸長因子Elonginの欠失による細胞早期老化の機構の解析Principal Investigator
- Principal Investigator
  
  麻生悌二郎
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kochi University
Role of transcription elongation factor Elongin on the determination of the cell fatePrincipal Investigator
- Principal Investigator
  
  ASO Teijiro
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Kochi University
転写伸長因子エロンガンの欠失による細胞分裂遅滞の原因の解明Principal Investigator
- Principal Investigator
  
  麻生悌二郎
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kochi University
Basic Strategy for the treatment of kidney cancer : identification and clinical utilization of new tumor suppressor genes or oncogenes closely correlated with VHL gene VHL
- Principal Investigator
  
  SHUIN Taro
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Kochi University
転写伸長因子エロンガンの細胞増殖制御機能の解析Principal Investigator
- Principal Investigator
  
  麻生悌二郎
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  高知大学(医学部)
転写伸長因子エロンガンの機能とVHL発がんとの関連性の解析Principal Investigator
- Principal Investigator
  
  麻生悌二郎
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  高知医科大学
エロンガン遺伝子欠損マウスを用いた転写伸長相の制御と細胞増殖制御との関連性の解明Principal Investigator
- Principal Investigator
  
  麻生悌二郎
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  高知大学(医学部)
Elucidation in the mechanism of human renal cell carcinoma cancer growth and micrometastasis with inactivation of VHL
- Principal Investigator
  
  SHUIN Taro
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Kochi University School of Medicine
VHL癌抑制蛋白の機能喪失による発がんのメカニズムの解析Principal Investigator
- Principal Investigator
  
  麻生悌二郎
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  高知医科大学
Elucidation of the molecular mechanisms of carcinogenesis by the VHL, tumor suppressor genePrincipal Investigator
- Principal Investigator
  
  ASO Teijiro
- Project Period (FY)
  2001 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kochi University
  高知大学(医学部)
Transcriptional elongation factor and its implication in human disease
- Principal Investigator
  
  KITAJIMA Shigetaka
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human genetics
- Research Institution
  Tokyo Medical and Dental University
転写伸長制御の破綻に基づく発がんのメカニズムの解明Principal Investigator
- Principal Investigator
  
  麻生悌二郎
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Japanese Foundation For Cancer Research
エロンガンによる転写伸長の制御と発がんとの関連性の解析Principal Investigator
- Principal Investigator
  
  麻生悌二郎
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  University of Tsukuba
エロンガンによる転写伸長の制御と発がんとの関連性の解析Principal Investigator
- Principal Investigator
  
  麻生悌二郎
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  University of Tsukuba
ElonginとVHL癌抑制蛋白による転写調節と細胞の増殖・分化との関連性の解析Principal Investigator
- Principal Investigator
  
  麻生悌二郎
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  University of Tsukuba
Elonginのin vivoの機能とVHL癌抑制蛋白による転写制御の機構の解析Principal Investigator
- Principal Investigator
  
  麻生悌二郎
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  University of Tsukuba
Analysis of gene regulatory function of TFIIF and elongin
- Principal Investigator
  
  SHIGETAKA Kitajima
- Project Period (FY)
  1997 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Human genetics
- Research Institution
  Tokyo Medical and Dental Univerisry
カルシウム信号を伝達する細胞内調節蛋白質の構造生物学Principal Investigator
- Principal Investigator
  
  麻生悌二郎, 伊倉光彦
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Structural biochemistry
- Research Institution
  University of Tsukuba

All 2020 2019 2017 2016 2015 2013 2012 2011 2009 2007 2006 2003 Other

All Journal Article Presentation Patent

[Journal Article] NRBP1-Containing CRL2/CRL4A Regulates Amyloid β Production by Targeting BRI2 and BRI3 for Degradation2020
- Author(s)
  Yasukawa T, Tsutsui A, Tomomori-Sato C, Sato S, Saraf A, Washburn MP, Florens L, Terada T, Shimizu K, Conaway RC, Conaway JW, Aso T.
- Journal Title
  
  Cell Reports
  
  Volume: 30 Pages: 3478-3491
- DOI
  10.1016/j.celrep.2020.02.059
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06855, KAKENHI-PROJECT-18K06959
[Journal Article] Cockayne syndrome B protein regulates recruitment of the Elongin A ubiquitin ligase to sites of DNA damage.2017
- Author(s)
  Weems JC, Slaughter BD, Unruh JR, Boeing S, Hall SM, McLaird MB, Yasukawa T, Aso T, Svejstrup JQ, Conaway JW, Conaway RC
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 292 Pages: 6431-6437
- DOI
  10.1074/jbc.c117.777946
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08177, KAKENHI-PROJECT-15K08279
[Journal Article] Assembly of the Elongin A ubiquitin ligase is regulated by genotoxic and other stresses.2015
- Author(s)
  Weems J.C., Slaughter B.D., Unruh J.R., Hall S.M., McLaird M.B., Gilmore J.M., Washburn M.P., Florens L., Yasukawa, T., Aso, T., Conaway, J.W., and Conaway, R.C.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 290 Pages: 15030-15041
- DOI
  10.1074/jbc.m114.632794
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08279
[Journal Article] Transcriptional properties of mammalian elongin A and its role in stress response2013
- Author(s)
  Kawauchi J, Inoue M, Fukuda M, Uchida Y, Yasukawa T, Conaway RC, Conaway JW, Aso T,
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 288(34) Pages: 24302-20315
- DOI
  10.1074/jbc.m113.496703
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23134502, KAKENHI-PLANNED-24118002, KAKENHI-PROJECT-24590279, KAKENHI-PROJECT-24590357, KAKENHI-PROJECT-24590373, KAKENHI-PUBLICLY-25134708
[Journal Article] Transcriptional elongation factor Elongin A regulates retinoic acid-induced gene expression during neuronal differentiation.2012
- Author(s)
  Yasukawa T, Bhatt S, Takeuchi T, Kawauchi J, Takahashi H, Tsutsui A, Muraoka T, Inoue M, Tsuda M, Kitajima S, Conaway RC, Conaway JW, Trainor PA, Aso T.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 2(5) Pages: 1129-1136
- DOI
  10.1016/j.celrep.2012.09.031
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700878, KAKENHI-PUBLICLY-23134502, KAKENHI-PROJECT-24590279, KAKENHI-PROJECT-24590357, KAKENHI-PROJECT-24590373, KAKENHI-PROJECT-24659121, KAKENHI-PROJECT-24689016, KAKENHI-PLANNED-24118002
[Journal Article] Degradation of p21^<Cip1> through APC/ C^<Cdc20> mediated ubiquitylation is inhibited by cyclin dependent kinase 2 in cardiomyocytes2011
- Author(s)
  Yamada K, Tamamori-Adachi M, Goto I, Iizuka M, Yasukawa T, Aso T, Okazaki T, and Kitajima S
- Journal Title
  
  J. Biol. Chem
  
  Volume: Vol.286 Pages: 44057-44066
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590311
[Journal Article] Identification of EloA-BPl, a novel Elongin A binding protein with an exonuclease homology domain.2003
- Author(s)
  Tamura K, MIyata K, Sugahara K, Onishi S, Shuin T, Aso T,.
- Journal Title
  
  Biochem Biophys Res Commun. 309(1)
  
  Pages: 189-195
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370515
[Patent] 認知症治療薬のスクリーニング方法2019
- Inventor(s)
  麻生悌二郎、安川孝史
- Industrial Property Rights Holder
  麻生悌二郎、安川孝史
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-088444
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-18K06959
[Presentation] ChIP-sequence解析を用いた転写伸長因子Elongin Aの標的遺伝子の同定2016
- Author(s)
  安川孝史、筒井文、佐藤チエリ、佐藤滋生、Ronald C. Conaway、Joan W. Conaway、麻生悌二郎
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-12-02
- Data Source
  KAKENHI-PROJECT-15K08279
[Presentation] Role of Transcription Elongation Factor Elongin A in The Sensory Nervous System Development.2012
- Author(s)
  Takashi Yasukawa, Junya Kawauchi, Hidehisa Takahashi, Aya Tsutsui, Ronald C. Conaway, Joan W. Conaway, Shigetaka Kitajima, Teijiro Aso
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  マリンメッセ福岡（福岡県）
- Data Source
  KAKENHI-PROJECT-24590357
[Presentation] Transcriptional Properties of Mammalian Elongin A and Its Role in Stress Response.2012
- Author(s)
  Makoto Inoue, Kawauchi, J., Tanaka, Y., Yasukawa, T., Aso, T., Kitajima, S.
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  マリンメッセ福岡（福岡県）
- Data Source
  KAKENHI-PROJECT-24590357
[Presentation] Mammalian Elongin A complex mediates DNA-damage-induced ubiquitylation and degradation of Rpb12009
- Author(s)
  Aso T. et al
- Organizer
  Ernest N. Morial Convention Center
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-21590311
[Presentation] Mammalian Elongin A complex mediates DNA-damage-induced ubiquitylation and degradation of Rpbl2009
- Author(s)
  Aso, T.
- Organizer
  ASBMB 2009
- Place of Presentation
  Ernest N. Morial Convention Center(New Orleans, USA)
- Year and Date
  2009-04-22
- Data Source
  KAKENHI-PROJECT-21590311
[Presentation] 動物細胞転写因子Elongin Aの機能解析2007
- Author(s)
  麻生悌二郎
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-12
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390082
[Presentation] Functional characterization of a mammalian transcription factor, Elongin A.2007
- Author(s)
  Aso, T
- Organizer
  30th Annual Meeting of the Molecular Biology Society of Japan
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2007-12-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390082
[Presentation] Homozygous deletion of mouse Elongin A results in embryonic lethality due to excessive apoptosis.2006
- Author(s)
  Aso, T.
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2006-06-20
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390082
[Presentation] 感覚神経系の発生・分化におけるElongin Aの標的遺伝子の同定
- Author(s)
  安川孝史, 村岡拓也, 筒井文, 佐藤チエリ, 佐藤滋生, 川内潤也, 井上允, 北嶋繁孝, Conaway Ronald C, Conaway Joan W, 麻生悌二郎
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都（国立京都国際会館）
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-24590357
[Presentation] ストレス応答におけるmammalian Elongin Aの特徴と役割
- Author(s)
  井上允, 川内潤也, 安川孝史, Conaway Ronald C., Conaway Joan W., 麻生悌二郎, 北嶋繁孝
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都（国立京都国際会館）
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-24590357
[Presentation] 転写伸長因子Elongin Aの標的遺伝子の網羅的探索
- Author(s)
  安川孝史, 筒井文, 村岡拓也, 佐藤チエリ, 佐藤滋生, Conaway Ronald C, Conaway Joan W, 北嶋繁孝, 麻生悌二郎
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜（パシフィコ横浜）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-24590357

1. KITAJIMA Shigetaka (30186241)

# of Collaborated Projects: 7 results

# of Collaborated Products: 8 results
2. SHUIN Taro (80179019)

# of Collaborated Projects: 7 results

# of Collaborated Products: 1 results
3. INOUE Keiji (00294827)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. OKUDA Heiwa (60325420)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. ATORU Oshiro (30160485)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. TERUMASA Tuchiya (20242109)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. YUKIO Yasukochi (60037398)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KAMADA Masayuki (90304683)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. KARASHIMA Takashi (60304672)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 伊倉光彦 (00142688)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 田中俊之 (10217052)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. KAWAUCHI Junya

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
13. TAKAHASHI Hidehisa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 安川孝史

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results

Asou Teijiro 麻生 悌二郎

麻生 悌二郎 アソウ テイジロウ

ASO Teijiro 麻生 悌二郎

TEIJIRO Aso 麻生 悌二郎

麻生 悌次郎 アソウ テイジロウ

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Development of an innovative anti-Alzheimer drug that selectively inhibits the ubiquitination of BRI2 and BRI3Principal Investigator

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Basic study for development of novel anti-dementia drug which selectively targets BRI2/3-ubiquitin ligasePrincipal Investigator

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Identification of Elongin A target genes and clarification of the mechanisms governing conversion of the Elongin complex from its elongation factor to its ubiquitin ligase formPrincipal Investigator

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In vivo role of transcriptional elongation/ubiquitin ligase factor ElonginPrincipal Investigator

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Role and mechanism of action of mammalian Elongin A in the stress responsePrincipal Investigator

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転写伸長因子Elonginの欠失による細胞早期老化の機構の解析Principal Investigator

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Role of transcription elongation factor Elongin on the determination of the cell fatePrincipal Investigator

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転写伸長因子エロンガンの欠失による細胞分裂遅滞の原因の解明Principal Investigator

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Basic Strategy for the treatment of kidney cancer : identification and clinical utilization of new tumor suppressor genes or oncogenes closely correlated with VHL gene VHL

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転写伸長因子エロンガンの細胞増殖制御機能の解析Principal Investigator

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転写伸長因子エロンガンの機能とVHL発がんとの関連性の解析Principal Investigator

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エロンガン遺伝子欠損マウスを用いた転写伸長相の制御と細胞増殖制御との関連性の解明Principal Investigator

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Asou Teijiro 麻生悌二郎

麻生悌二郎アソウテイジロウ

ASO Teijiro 麻生悌二郎

TEIJIRO Aso 麻生悌二郎

麻生悌次郎アソウテイジロウ