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Anai Hirofumi  穴井 博文

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ANAI Hirofumi  穴井 博文

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Researcher Number 20291544
Other IDs
Affiliation (Current) 2025: 大分大学, 医学部, 教授
Affiliation (based on the past Project Information) *help 2016 – 2024: 大分大学, 医学部, 教授
2008: Oita University, 医学部, 准教授
2008: Oita University, 医学部・心臓血管外科, 准教授
2007: Oita University, 医学部, 助教
2003: Oita University, Faculty of Medicine, Assistant Professor, 医学部, 講師
2002: 大分医科大学, 医学部, 講師
1998 – 2000: 大分医科大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Thoracic surgery / Thoracic surgery
Except Principal Investigator
Basic Section 55030:Cardiovascular surgery-related / Thoracic surgery / Basic Section 59040:Nutrition science and health science-related / Basic Section 90120:Biomaterials-related / Basic Section 55060:Emergency medicine-related / Basic Section 90110:Biomedical engineering-related / Biomedical engineering/Biomaterial science and engineering / Cardiovascular surgery
Keywords
Principal Investigator
循環補助 / 斜流ポンプ / 補助循環 / イオンチャネル / 電気生理学 / lacZ / 心移植 / アデノウィルス / イオンチャンネル
Except Principal Investigator
再生医療 … More / 生体内組織形成術 / 人工血管 / 移植 / 大動脈 / 生体材料 / 大血管 / 生体内組織生成術 / 代用臓器 / 異種移植 / 弁形成術 / 外科 / 生物・生体工学 / 移植・再生医療 / 弁膜症 / 自己組織化 / 心臓弁膜症 / 大動脈弁 / Mixed-flow pump / Continuous flow / Cardiopulmonary bypass / 異種I移植 / 冠動脈 / 冠動脈バイパス術 / 生成医療 / 狭心症 / 虚血性心疾患 / 冠動脈バイパス / 細胞老化 / 粥状動脈硬化 / 血管平滑筋細胞 / 分枝 / 血流解析 / 大動脈瘤 / 弓部大動脈瘤 / 自己組織 / 大動脈手術 / 認知機能傷害 / 光治療 / 認知機能障害 / 概日リズム / 光療法 / 敗血症 / バスキュラーアクセス / 重症下肢虚血 / 動物実験 / 血管 / 組織工学 / バイオチューブ / 大動脈外科 / 小児心臓外科 / 心臓血管外科 / 先天性心疾患 / 脱細胞 / 弁置換術 / 再生医学 / 尾崎法 / 光造形 / 組織再生 / 人工弁 / 生体医療材料 / 生体内組織合成 / 自己心膜 / 心臓外科 / 生体内組織形成 / 自家移植 / 大動脈弁置換 / 慢性動物実験 / 生体医用工学 / Mixed-flow.pump / profound hypothermia / platelet microaggregation / platelet spontaneous aggregation / ヘパリン / 超低体温体外循環 / 血小板微少凝集 / 超低温体外循環 / 血小板微小凝集 / 血小板自然凝集 Less
  • Research Projects

    (12 results)
  • Research Products

    (11 results)
  • Co-Researchers

    (22 People)
  •  粥状動脈硬化を標的とした「血管平滑筋細胞老化マーカー」の同定

    • Principal Investigator
      加藤 優子
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Oita University
  •  Development of bypass graft for coronary bypass grafting using in-body tissure architecture technique

    • Principal Investigator
      宮本 伸二
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55030:Cardiovascular surgery-related
    • Research Institution
      Oita University
  •  Development of bifurcated curved bio-tube for the aorta with in-body tissue architecture

    • Principal Investigator
      Shuto Takashi
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 90120:Biomaterials-related
    • Research Institution
      Oita University
  •  Light elicited circadian re-entrainment as a treatment for post-sepsis cognitive impairment

    • Principal Investigator
      小山 淑正
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      Oita University
  •  Development of self-growth biotube for large blood vessel reconstruction by stereolithography and in-body tissue architecture

    • Principal Investigator
      Miyamoto Shinji
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55030:Cardiovascular surgery-related
    • Research Institution
      Oita University
  •  Tomorrow's Vascular Surgery Induced by World's Longest Tissue-engineered Vascular Grafts

    • Principal Investigator
      Nakayama Yasuhide
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 90110:Biomedical engineering-related
    • Research Institution
      Oita University
  •  Development of biovalves created by in-body tissue architecture for xenotransplantation

    • Principal Investigator
      Shuto Takashi
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biomedical engineering/Biomaterial science and engineering
    • Research Institution
      Oita University
  •  Development of biocompatible bio leaflet for aortic valve reconstruction using in-body architecture technology

    • Principal Investigator
      Miyamoto Shinji
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cardiovascular surgery
    • Research Institution
      Oita University
  •  DEVELOPMENT OF THE CIRCULATORY ASSIST DEVICE WITH SMALL SIZED MIXED FLOW BLOOD PUMPPrincipal Investigator

    • Principal Investigator
      ANAI Hirofumi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Oita University
  •  Clinical evaluation and basic research for long term use of a newly developed miniature mixed-flow pump

    • Principal Investigator
      HADAMA Tetsuo
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Thoracic surgery
    • Research Institution
      OITA UNIVERSITY
  •  Study of platelet injury during profound hypothermic extracorponeal circulation

    • Principal Investigator
      MIYAMOTO Shinji
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      OITA MEDICAL UNIVERSITY
  •  移植心筋へのイオンチャネル遺伝子導入による心臓電気興奮性の制御Principal Investigator

    • Principal Investigator
      穴井 博文
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Thoracic surgery
    • Research Institution
      大分医科大学

All 2021 2019 2018 2017 2007

All Journal Article Presentation

  • [Journal Article] Aortic valve neocuspidization with in-body tissue-engineered autologous membranes: preliminary results in a long-term goat model2021

    • Author(s)
      Kawashima Takayuki、Umeno Tadashi、Terazawa Takeshi、Wada Tomoyuki、Shuto Takashi、Nishida Haruto、Anai Hirofumi、Nakayama Yasuhide、Miyamoto Shinji
    • Journal Title

      Interactive CardioVascular and Thoracic Surgery

      Volume: - Issue: 6 Pages: 969-977

    • DOI

      10.1093/icvts/ivab015

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H04447, KAKENHI-PROJECT-20K20174
  • [Journal Article] 生体内組織形成術(IBTA)による大動脈弁再建術の開発2018

    • Author(s)
      河島 毅之, 梅野 惟史, 岡本 啓太郎, 和田 朋之, 首藤 敬史, 寺澤 武, 中山 泰秀, 穴井 博文, 巽 英介, 宮本 伸二
    • Journal Title

      Japanese Journal of Cardiovascular Surgery

      Volume: 47 Issue: 4 Pages: xxix-xxxiii

    • DOI

      10.4326/jjcvs.47.xxix

    • NAID

      130007431813

    • ISSN
      0285-1474, 1883-4108
    • Year and Date
      2018-07-15
    • Language
      Japanese
    • Data Source
      KAKENHI-PROJECT-16H05426
  • [Presentation] One year Results of Aortic Valve Reconstruction Using an in body Tissue Architecture Goat Model”2019

    • Author(s)
      Keitaro Okamoto, Takayuki Kawashima, Kyouhei Hatori1, Tomoyuki Wada, Takeshi Terazawa, Tadashi Umeno, Takashi Shuto, Hirofumi Anai, Yasuhide Nakayama, Shinji Miyamoto
    • Organizer
      The Heart Valve Society 2019 Annual Scientific Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H02101
  • [Presentation] iBTAを用いた大動脈弁再建術の山羊1年成績2019

    • Author(s)
      河島毅之、梅野惟史、和田朋之、首藤敬史、寺澤 武、中山泰秀、穴井博文、宮本伸二
    • Organizer
      第72回日本胸部外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-17H02101
  • [Presentation] Development of a New Aortic Valve Reconstruciton Material Using In-body Tissue Architecture.2018

    • Author(s)
      Takayuki Kawashima, Tadashi Umeno, Terasawa Takeshi, Keitaro OKamoto, Kyouhei Hatori, Tomoyuki Wada, Takesi Shuto, Hirofumi Anai, Eisuke Tatsumi, Yasuhide Nakayama, Shinji Miyamoto
    • Organizer
      American Heart Association
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05426
  • [Presentation] 生体内組織形成術(IBTA)によるバイオシートを用いた大動脈弁再建術の開発2017

    • Author(s)
      河島毅之、梅野惟史、岡本啓太郎、和田朋之、溝口貴之、首藤敬史、寺澤武、中山泰秀、穴井博文、巽英介
    • Organizer
      第55回日本人工臓器学会
    • Data Source
      KAKENHI-PROJECT-16H05426
  • [Presentation] 生体内組織形成術(IBTA)による大動脈弁再建組織の開発2017

    • Author(s)
      河島毅之、梅野惟史、岡本啓太郎、和田朋之、溝口貴之、首藤敬史、寺澤武、中山泰秀、穴井博文、巽英介、宮本伸二
    • Organizer
      第48回日本心臓血管外科学会学術総会
    • Data Source
      KAKENHI-PROJECT-16H05426
  • [Presentation] 人工結合組織シート(バイオシート)の作成鋳型による内部構造変化2017

    • Author(s)
      河島毅之、岡本 啓太郎、梅野 惟史、穴井 博文、和田 朋之、首藤 敬史、寺澤 武、中山 泰秀、巽 英介、田北 薫子、島田 達生、宮本 伸二
    • Organizer
      第33回医学生物学電子顕微鏡技術学会学術講演会
    • Data Source
      KAKENHI-PROJECT-16H05426
  • [Presentation] 生体内組織形成術(IBTA)を用いた大動脈弁再建組織の開発2017

    • Author(s)
      河島毅之、梅野惟史、岡本啓太郎、和田朋之、溝口貴之、首藤敬史、寺澤武、中山泰秀、穴井博文、巽英介、宮本伸二
    • Organizer
      第123回日本循環器学会九州地方会
    • Data Source
      KAKENHI-PROJECT-16H05426
  • [Presentation] 体外循環用斜流式血液ポンプJMS Mixflowの長期使用へ向けての検討2007

    • Author(s)
      穴井博文
    • Organizer
      第45回日本人工臓器学会大会
    • Place of Presentation
      大阪市
    • Year and Date
      2007-10-30
    • Data Source
      KAKENHI-PROJECT-19591633
  • [Presentation] 体外循環用斜流式血液ポンプJMS Mixflow^<TM>の長期使用へ向けての検討2007

    • Author(s)
      穴井博文, 宮本伸二, 和田朋之, 荒木賢二, 押川満雄, 他
    • Organizer
      第45回日本人工臓器学会大会
    • Place of Presentation
      大阪市
    • Data Source
      KAKENHI-PROJECT-19591633
  • 1.  MIYAMOTO Shinnji (70253797)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 8 results
  • 2.  Nakayama Yasuhide (50250262)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 8 results
  • 3.  Shuto Takashi (60649763)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 7 results
  • 4.  岩井 良輔 (60611481)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 5.  WADA Tomoyuki (60325701)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 8 results
  • 6.  HADAMA Tetsuo (00145377)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  河島 毅之 (20791049)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 7 results
  • 8.  西邑 隆徳 (10237729)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 9.  SAKO Hidenori (20315344)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  岡本 啓太郎 (50723524)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 11.  SHIGEMITSU Osamu (40215968)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  平岡 善憲 (90253799)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  小野 克重 (40253778)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  寺澤 武 (20815401)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 15.  小山 淑正 (40468012)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  徳丸 治 (40360151)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  松本 重清 (90274761)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  加藤 優子 (50580875)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  白石 裕士 (80452837)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  HAMAMOTO Hirotsugu
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  IWATA Eriko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  Ozaki Shigeyuki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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