Hirose Yoshinobu 廣瀬善信

… Alternative Names

廣瀬善信ヒロセヨシノブ

HIROSE Yoshinobu 廣瀬善信

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Researcher Number	20293574
Other IDs
Affiliation (Current)	2025: 大阪医科薬科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2021 – 2023: 大阪医科薬科大学, 医学部, 教授 2018 – 2020: 大阪医科大学, 医学部, 教授 2013 – 2016: 大阪医科大学, 医学部, 教授 2014: 大阪医科大学, 病理学, 教授 2007: 岐阜大学, 医学部付属病院, 准教授 … More 2007: Gifu University, Hospital, Associate professor 2006: 岐阜大学, 医学部付属病院, 助教授 2004 – 2005: 岐阜大学, 医学部附属病院, 助教授 2004: Gifu University, School of Medicine, University Hospital, Associate Professor, 医学部付属病院, 助教授 2002 – 2003: MD. PhD., Gifu Univ. Sch. Med. Dept. Pathol., Assistant professor, 医学部附属病院, 助手 2001: 岐阜大学, 医学部・附属病院, 助手 Less
Review Section/Research Field	Principal Investigator Basic Section 49020:Human pathology-related / Tumor diagnostics / Experimental pathology Except Principal Investigator Experimental pathology / Biological Sciences / Basic Section 55020:Digestive surgery-related / Basic Section 52040:Radiological sciences-related / Human pathology / Respiratory organ internal medicine
Keywords	Principal Investigator 進行大腸癌 / 乳酸脱水素酵素 / グルタミナーゼ / 転移 / 代謝 / 簇出 / 脈管侵襲 / 代謝酵素 / 治療提案 / 病理解析 … More / HER2 / BRAF / 腫瘍内不均一性 / HER3 / EGFR / 病理評価 / 分子標的薬 / 大腸癌 / アゾキシメタン / obマウス / dbマウス / 化学発がん / インスリン / レプチン / 肥満 / 大腸がん … More Except Principal Investigator BCAC / 大腸癌 / 前癌病変 / premalignant lesion / colon cancer / gastric cancer / tcf / beta-catenin / Premalignant lesion / Colon cancer / ACF / APC / β-Catenin / β-catenin / 膵癌 / 癌移植 / 膵臓癌 / 膵臓がん / ゼブラフィッシュ / 造影ダイナミックMRI / 拡散強調像 / 斜位断面像 / 膀胱癌 / staging / bladder cancer / multiparametric / MRI / 膀胱がん / 過剰診断防止 / 国際診断基準 / 膀胱腫瘍 / マルチパラメトリックMRI / VI-RADS / tcf pathway / colon carcinogenesis / 大腸発がん / Tcf / p53 gene / Min mouse / Apc gene / p53 / Minマウス / Apc遺伝子 / 大腸発癌 / PPARαアゴニスト / 発がん / 高インシュリン血症 / 高脂血症 / 肥満 / 腫瘍 / 肺 / PPARα アゴニスト / carcinogenesis / hyperinsulinemia / hyperlipidemia / obese / neoplasms / lung / PPARalpha agonist / paneth cell / スクリーニング / アポトーシス / 化学予防 / 大腸がん Less

進行大腸癌における転移特異的な代謝表現型に関する研究Principal Investigator
- Principal Investigator
  
  廣瀬善信
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Osaka Medical and Pharmaceutical University
がん細胞ゼブラフィッシュ移植モデルによるアッセイ系の構築～膵癌克服への布石～
- Principal Investigator
  
  朝隈光弘
- Project Period (FY)
  2019 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Osaka Medical and Pharmaceutical University
A Developing Diagnostic Method of Invasion Depth about Bladder Cancer, using a new Multi-Parametric MRI and applying it to a Therapeutic Strategy
- Principal Investigator
  
  NARUMI Yoshiifumi
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Kyoto Tachibana University
  Osaka Medical College
Pathological evaluation for advanced colorectal cancer aiming at treatment proposal for molecular targeted drugsPrincipal Investigator
- Principal Investigator
  
  Hirose Yoshinobu
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor diagnostics
- Research Institution
  Osaka Medical College
Suppressive effects of PPARalpha agonist against pulmonary carcinogenesis in mice
- Principal Investigator
  
  KUNO Toshiya
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nagoya City University
  Gifu University
Research on premalignant lesions using beta-catenin/Tcfreporter mice
- Principal Investigator
  
  MORI Hideki
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Gifu University
パネート細胞の大腸および胃発癌に係わる意義に関する実験的研究
- Principal Investigator
  
  森秀樹
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Gifu University
新規前がん病変とアポトーシスを指標とする大腸がん予防因子検出のための研究
- Principal Investigator
  
  MORI Hideki
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Gifu University
レプチン受容体異常マウスを用いた大腸発がんにおける肥満起因性危険因子の同定Principal Investigator
- Principal Investigator
  
  廣瀬善信
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Gifu University
Role of premalignant lesion and its significance in the promotion/progssion stage of colon carcinogenesis in Apc min mice.
- Principal Investigator
  
  MORI Hideki
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Gifu University
Pathological analysis for premalignant lesions of colon cancer
- Principal Investigator
  
  MORI Hideki
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human pathology
- Research Institution
  Gifu University

All 2024 2023 2018 2017 2014 2013 2012 2007 2004

All Journal Article Presentation

[Journal Article] Intratumoral metabolic heterogeneity of colorectal cancer2023
- Author(s)
  Hirose Yoshinobu、Taniguchi Kohei
- Journal Title
  
  American Journal of Physiology-Cell Physiology
  
  Volume: 325 Issue: 4 Pages: C1073-C1084
- DOI
  10.1152/ajpcell.00139.2021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06989
[Journal Article] 分子標的治療と病理2017
- Author(s)
  栗栖義賢, 辻求, 廣瀬善信
- Journal Title
  
  大阪医科大学雑誌
  
  Volume: 75 Pages: 81-81
- NAID
  40020729267
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25430136
[Journal Article] The Peroxisome Proliferator-Activated Receptor (PPAR) α Agonist Fenofibrate Suppresses Chemically Induced Lung Alveolar Proliferative Lesions in Male Obese Hyperlipidemic Mice2014
- Author(s)
  Toshiya Kuno, Kazuya Hata, Manabu Takamatsu, Akira Hara, Yoshinobu Hirose, Satoru Takahashi, Katsumi Imaida, Takuji Tanaka
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 15 Issue: 5 Pages: 9160-72
- DOI
  10.3390/ijms15059160
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24591159, KAKENHI-PROJECT-221S0001
[Journal Article] Predictors of lymph node metastasis in T1 colorectal carcinoma: an immunophenotypic analysis of 265 patients2014
- Author(s)
  Tsukasa Nishida, Yutaro Egashira, Hiroshi Akutagawa, Mototsugu Fujii, Kazuhisa Uchiyama, Yuro Shibayama, Yoshinobu Hirose
- Journal Title
  
  Dis Colon Rectum
  
  Volume: 57
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25430136
[Journal Article] A Case of Small Ascending Colon Cancer Requiring Additional Resection due to Expansive Lymphatic Involvement2013
- Author(s)
  野中健一、浅井竜一、安福至、富田弘之、松橋延壽、廣瀬善信、高橋孝夫、山口和也、長田真二、吉田和弘
- Journal Title
  
  The Japanese Journal of Gastroenterological Surgery
  
  Volume: 46 Issue: 10 Pages: 777-783
- DOI
  10.5833/jjgs.2012.0271
- NAID
  130004560883
- ISSN
  0386-9768, 1348-9372
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25430136
[Journal Article] Modifying effect of dietary sesaminol glucosides on the formation of azoxymethane-induced premalignant lesions of rat colon.2007
- Author(s)
  Sheng HQ, Hirose Y et al.
- Journal Title
  
  Cancer Lett. 246
  
  Pages: 63-68
- Data Source
  KAKENHI-PROJECT-17390112
[Journal Article] Enhancement of development of azoxymethane-induced colonic premalignant lesions in C57BL/KsJ-db/db mice2004
- Author(s)
  Hirose Y. et al.
- Journal Title
  
  Carcinogenesis 25
  
  Pages: 821-825
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390124
[Journal Article] Aberrant crypt foci and beta-catenin accumulated crypts : significance and roles for colorectal carcinogenesis2004
- Author(s)
  Mori, H., Yamada, Y., Kuno, T., Hirose, Y.
- Journal Title
  
  Mutation Research 566・3
  
  Pages: 191-208
- Data Source
  KAKENHI-PROJECT-15790200
[Journal Article] Enhancement of development of azoxymethane-induced colonic premaligmant lesions in C57BL/KsJ-db/db mice2004
- Author(s)
  Hirose Y. et al.
- Journal Title
  
  Carcinogenesis 25
  
  Pages: 821-825
- Data Source
  KAKENHI-PROJECT-15390124
[Journal Article] Enhancement of development of azoxymethane-induced colonic premalignant lesions in C57BL/KsJ-db/db mice.2004
- Author(s)
  Hirose Y et al.
- Journal Title
  
  Carcinogenesis 25
  
  Pages: 821-825
- Data Source
  KAKENHI-PROJECT-16021219
[Journal Article] Enhancement of development of azoxymethane-induced colonic premalignant lesions in C57BL/KsJ-db/db mice2004
- Author(s)
  Hirose, Y., Hata, K., Kuno, T., Yoshida, K., Mori, H., et al.
- Journal Title
  
  Carcinogenesis 25・5
  
  Pages: 821-825
- Data Source
  KAKENHI-PROJECT-15790200
[Presentation] 転移を伴う信仰大腸癌における代謝表現型の病理解析2024
- Author(s)
  大西悠介、石田光明、廣瀬善信
- Organizer
  第113回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-22K06989
[Presentation] 膀胱癌のＭＲＩ深達度診断 ―VI-RADSプロジェクト―2018
- Author(s)
  重里　寛、鳴海善文、東山　央、稲田悠紀、山本聖人、坂根　誠、中井　豪、山本和宏、廣瀬善信、東　治人、竹内　充、Valeria Panabianco
- Organizer
  第319回日本医学放射線学会関西地方会
- Data Source
  KAKENHI-PROJECT-18K07735
[Presentation] A PPARa agonist, fenofibrate suppress 4NQO-induced pulmonary proliferative lesions in obese and hyperlipidemic mice.2012
- Author(s)
  Kuno T, Tanaka T, Takamatsu M, Hatano Y, Tomita H, Hirose Y, Hirata A, Hara A
- Organizer
  71th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24591159
[Presentation] Fenofibrateの4NQO誘発肥満、高脂血症マウス肺増殖性病変に及ぼす影響2012
- Author(s)
  久野壽也、田中卓二、廣瀬善信、平田暁大、原明
- Organizer
  がん予防学会
- Place of Presentation
  岐阜
- Data Source
  KAKENHI-PROJECT-24591159

1. MORI Hideki (70021433)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
2. YAMADA Yasuhiro (70313872)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. KUNO Toshiya (00345779)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
4. YOSHIMI Naoki (30166996)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. HARA Akira (10242728)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. MATSUNAGA Kengo (00402173)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. NARUMI Yoshiifumi (90273664)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 東治人 (40231914)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 重里寛 (80794768)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 東山央 (80738104)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 稲田悠紀 (50530531)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 大須賀慶悟 (90332741)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 山本聖人 (80779710)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. 朝隈光弘 (40559390)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 小村和正 (10789853)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 小野富三人 (70743996)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 谷口高平 (70779686)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Hirose Yoshinobu 廣瀬 善信

廣瀬 善信 ヒロセ ヨシノブ

HIROSE Yoshinobu 廣瀬 善信

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Pathological evaluation for advanced colorectal cancer aiming at treatment proposal for molecular targeted drugsPrincipal Investigator

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レプチン受容体異常マウスを用いた大腸発がんにおける肥満起因性危険因子の同定Principal Investigator

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[Journal Article] Intratumoral metabolic heterogeneity of colorectal cancer2023

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DOI

Data Source

[Journal Article] 分子標的治療と病理2017

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Journal Title

NAID

Data Source

[Journal Article] The Peroxisome Proliferator-Activated Receptor (PPAR) α Agonist Fenofibrate Suppresses Chemically Induced Lung Alveolar Proliferative Lesions in Male Obese Hyperlipidemic Mice2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Predictors of lymph node metastasis in T1 colorectal carcinoma: an immunophenotypic analysis of 265 patients2014

Hirose Yoshinobu 廣瀬善信

廣瀬善信ヒロセヨシノブ

HIROSE Yoshinobu 廣瀬善信