Hayashi Yoshihito 林要人

… Alternative Names

HAYASHI Yoshihito 林要人

Less

Researcher Number	20295223
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2014 – 2016: 宮崎大学, 医学部, 准教授 2011: 宮崎大学, 医学部, 講師 2009 – 2010: University of Miyazaki, 医学部, 助教 2007: University of Miyazaki, Faculty of Medicine, Assistant Professor 2006: 宮崎大学, 医学部, 助手 2003 – 2004: 宮崎大学, 医学部, 助手 1999 – 2002: 宮崎医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Psychiatric science / Psychiatric science Except Principal Investigator Psychiatric science
Keywords	Principal Investigator βアミロイド / free radical / フリーラジカル / oligomer / beta amyloid / ラミニン / 神経毒性 / 凝集 / laminin / β amyloid … More / NMDA / メラトニン / コルチゾール / 唾液 / 介護うつ / 介護負担 / BPSD / バイオマーカー / 認知症 / 神経細胞保護 / オリゴマー / アルツハイマー型認知症 / PC12 / IKVAV / PC12細胞 / βアミロイド蛋白 … More Except Principal Investigator Alzheimer's disease / Laminin peptide / Therapeutic agent / Diagnostic marker / Cerebrospinal fluid / ELISA / Vascular dementia / Laminin / βアミロイド / IKLLI / YFQRYLI / ラミニンペプチド / 脳血管性痴呆(VaD) / アルツハイマー病(AD) / 髄液 / wholeラミニン / ラミニンγ / Theraeutic agent / βaryloid / integrin / IKVAN / Laminin fragment / アルツハイマー / YFOQRYLI / アルツハイマー病 / インテグリン / IKVAV / ラミニンフラグメント Less

Biomarkers predict the occurrence of BPSDPrincipal Investigator
- Principal Investigator
  
  Hayashi Yoshihito
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  University of Miyazaki
The efficacy of anti-Aβoligomer antibody to the toxicity of Aβto neuronal cellsPrincipal Investigator
- Principal Investigator
  
  HAYASHI Yoshihito
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  University of Miyazaki
Free radical production from betaAmyloid oligomers and mechanism of neurotoxicity deduced from themPrincipal Investigator
- Principal Investigator
  
  HAYASHI Yoshihito
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  University of Miyazaki
Free -radical generation by amyloid p protein and the protective effect by laminin against amyloid β-protein induced toxicityPrincipal Investigator
- Principal Investigator
  
  HAYASHI Yoshihito
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  University of Miyazaki
  宮崎医科大学
βアミロイド凝集によるフリーラジカル発生と細胞毒性に関するin vitro研究Principal Investigator
- Principal Investigator
  
  林要人
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Psychiatric science
- Research Institution
  宮崎医科大学
Aralysis of laminin in brain as a inbibifor of βaryloidogenosis
- Principal Investigator
  
  TASHIRO Kenichiro
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Kyushu University of Health and Welfare
  宮崎医科大学
Measuremrnt of laminins in cerebrospinal fluid (CSF) obtained from dementia using antibodies against laminin and laminin peptide -Developping a diagnostic biological marker-
- Principal Investigator
  
  MATSUDA Kazunori
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Miyazaki Medical College

All 2017 2015 2014 2012 2011 2010 2009 2007 2006 2004 Other

All Journal Article Presentation

[Journal Article] 認知症の行動・心理症状に対する薬物療法の注意点─抑肝散の可能性─2017
- Author(s)
  石田康，林要人，宇田川充隆，岡原一徳
- Journal Title
  
  臨床と研究
  
  Volume: 94 (1) Pages: 134-137
- Data Source
  KAKENHI-PROJECT-26461751
[Journal Article] An Open-label trial of Yokukansan on Sleep Disturbance in Alzheimer's disease and other Dementia2015
- Author(s)
  Y.Hayashi,Y.Ishida,K.Okahara ,Y.Mitsuyama
- Journal Title
  
  J.Prev Alzheimer Dis
  
  Volume: 2(3) Pages: 172-177
- DOI
  10.14283/jpad.2015.70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461751
[Journal Article] レビー小体型認知症患者に対する抑肝散投与の有用性　長期投与の有効性および安全性に関する後方視的観察研究2014
- Author(s)
  岡原一徳, 石田康, 林要人, 土屋利紀
- Journal Title
  
  Dementia Japan
  
  Volume: 28 Pages: 97-107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461751
[Journal Article] 認知症患者の行動・心理症状(BPSD)に対する抑肝散長期投与の安産性および有効性の検討2012
- Author(s)
  岡原一徳、石田康、林要人、土屋利紀
- Journal Title
  
  Dementia Japan
  
  Volume: 26 Pages: 196-205
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591524
[Journal Article] アルツハイマー型認知症の周辺症状(BPSD)に対する抑肝散の効果2010
- Author(s)
  林要人, 他
- Journal Title
  
  Geriatric Medicine(老年医学)
  
  Volume: 48 Pages: 831-838
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591524
[Journal Article] Treatment of behavioral and psychological symptoms of Alzheimer-type dementia with Yokukansan in clinical practice2010
- Author(s)
  Hayashi Y, Ishida Y, Inoue T, Udagawa M, Takeuchi K, Yoshimuta H, Kiue K, Ninomiya Y, Kawano J, Sameshima T, Kawahara T, Goto I, Shudo K, Kurayama S, Nakamura J, Okahara K, Mitsuyama Y
- Journal Title
  
  Prog Neuropsychopharmacol Biol Psychiatry
  
  Volume: 34-3 Pages: 541-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591524
[Journal Article] Effects of Yokukansan on behavioral and psychological symptoms of dementia in regular treatment for Alzheimer's disease2010
- Author(s)
  Okahara K, Ishida Y, Hayashi Y, Inoue T, Tsuruta K, Takeuchi K, Yoshimuta H, Kiue K, Ninomiya Y, Kawano J, Yoshida K, Noda S, Tomita S, Fujimoto M, Hosomi J, Mitsuyama Y
- Journal Title
  
  Prog Neuropsychopharmacol Biol Psychiatry.
  
  Volume: 34-3 Pages: 532-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591524
[Journal Article] Treatment of behavioral and psychological symptoms of Alzheimer-type dementia with Yokukansan in clinical practice.2010
- Author(s)
  Yoshihito Hayashi, et al
- Journal Title
  
  Prog Neuropsychopharmacol Biol Psychiatry
  
  Volume: 34 Pages: 541-545
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591524
[Journal Article] アルツハイマー型認知症の周辺症状(BPSD)に対する抑肝散の効果-日常診療下における検討:入院患者における部分集団解析-2010
- Author(s)
  林要人, 石田康, 井上輝彦, 宇田川充隆, 竹内康三, 木上幸一郎, 二宮嘉正, 河野次郎, 鮫島哲郎, 川原岳, 後藤勇, 首藤謙二, 倉山茂樹, 中村純五, 岡原一徳, 三山吉夫
- Journal Title
  
  Geriatric Medicine(老年医学)
  
  Volume: 48巻6号 Pages: 831-838
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591524
[Journal Article] アルツハイマー型認知症患者の行動および心理症状に対する抑肝散の効果2009
- Author(s)
  林要人, 石田康, 岡原一徳, 三山吉夫
- Journal Title
  
  脳21
  
  Volume: 12巻4号 Pages: 452-455
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591524
[Journal Article] アルツハイマー型認知症患者の行動および心理症状に対する抑肝散の効果-日常診療下における検討-2009
- Author(s)
  林要人, 他
- Journal Title
  
  脳21 12
  
  Pages: 452-455
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591524
[Journal Article] ベンゾジアゼピン系薬物依存症にSSRIが有効であった1例2007
- Author(s)
  船橋英樹, 林要人, 他
- Journal Title
  
  九州神経精神医学 53
  
  Pages: 74-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591298
[Journal Article] 宮崎大学医学部附属病院精神科におけるコンサルテーション・リエゾン精神医療の現状2007
- Author(s)
  長友慶子, 並木薫, 林要人, 他
- Journal Title
  
  宮崎県医師会医学会誌 312
  
  Pages: 15-20
- NAID
  120007123010
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591298
[Journal Article] 抗うつ薬とperospironeによる増強療法が奏功した薬物治療抵抗性うつ病の2症例2007
- Author(s)
  長友慶子, 石塚雄太, 林要人, 他
- Journal Title
  
  臨床精神医学 36
  
  Pages: 1293-1298
- NAID
  40015679883
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591298
[Journal Article] ベンゾジアゼピン系薬物依存症にSSRIが有効であった1例2007
- Author(s)
  船橋英樹, 林要人, 他
- Journal Title
  
  九州神経精神医学 53
  
  Pages: 74-74
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591298
[Journal Article] 宮崎大学医学部附属病院精神科におけるコンサルテーション・リエゾン精神医療の現状2007
- Author(s)
  長友慶子, 並木薫, 林要人, 他
- Journal Title
  
  宮崎県医師会医学会誌 312
  
  Pages: 15-20
- NAID
  120007123010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591298
[Journal Article] 抗うつ薬とperospironeによる増強療法が奏功した薬物治療抵抗性うつ病の2症例2007
- Author(s)
  長友慶子, 石塚雄太, 林要人, 他
- Journal Title
  
  臨床精神医学 36
  
  Pages: 1293-1298
- NAID
  40015679883
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591298
[Journal Article] Plasma amyloid-beta concentrations in Alzheimer's disease:an alternative hypothesis2006
- Author(s)
  Fullwood NJ, Hayashi Y, Allsop D.
- Journal Title
  
  Lancet Neurol 12
  
  Pages: 1000-1001
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591298
[Journal Article] Plasma amyloid-beta concentrations in Alzheimer's disease : an alternative hypothesis.2006
- Author(s)
  Fullwood NJ, Hayashi Y, Allsop D
- Journal Title
  
  Lancet Neurol. 5・12
  
  Pages: 1000-1
- Data Source
  KAKENHI-PROJECT-18591298
[Journal Article] EPR evidence of hydroxyl radical generation as an initiator of lipid paroxidation in amyloid β-protein-stimulated PC12 cells2004
- Author(s)
  Yoshihito Hayashi, Yuto Ueda, Akira Nakajima, Yoshio Mitsuyama
- Journal Title
  
  Brain Research 1025
  
  Pages: 29-34
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591235
[Journal Article] EPR evidence of hydroxyl radical generation as an initiator of lipid peroxidation in amyloid β-protein-stimulated PC12 cells2004
- Author(s)
  Yoshihito Hayashi, Yuto Ueda, Akira Nakajima, Yoshio Mistuyama
- Journal Title
  
  Brain Research 1025
  
  Pages: 29-34
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591235
[Presentation] An open label study to ascertain the effect of a traditional Japanese medicine yokukansan, short-term treatment on the BPSD in patients with AD2011
- Author(s)
  Hayashi Y, Ishida Y, Okahara K, Mitsuyama Y
- Organizer
  アメリカ精神医学会
- Place of Presentation
  ハワイ
- Data Source
  KAKENHI-PROJECT-21591524
[Presentation] An open label study to ascertain the effect of a traditional Japanese medicine yokukansan, short-term treatment on the BPSD in patients with AD2011
- Author(s)
  Yoshihito Hayashi
- Organizer
  アメリカ精神医学会
- Place of Presentation
  アメリカ合衆国ハワイ
- Year and Date
  2011-05-16
- Data Source
  KAKENHI-PROJECT-21591524
[Presentation] A randomized, controlled comparative open label study of a traditional Japanese medicine, yokukansan, on the behavioral and psychological symptoms of dementia in patients with Alzheimer's disease2009
- Author(s)
  Yoshihito Hayashi, Y Mitsuyama, Y Ishida
- Organizer
  International Psychogeriatric Association 14^<th> International Congress
- Place of Presentation
  カナダモントリオール国際会議場
- Year and Date
  2009-09-04
- Data Source
  KAKENHI-PROJECT-21591524
[Presentation] A multicenter open label study to investigate the effect of a traditional Japanese medicine, yokukansan, on the behavioral and psychological symptoms of dementia in patients with Alzheimer's disease2009
- Author(s)
  Yoshihito Hayashi, Y Mitsuyama, Y Ishida
- Organizer
  International Psychogeriatric Association 14^<th> International Congress
- Place of Presentation
  カナダモントリオール国際会議場
- Year and Date
  2009-09-04
- Data Source
  KAKENHI-PROJECT-21591524
[Presentation] A multicenter open label study to investigate the effect of a traditional Japanese medicine, yokukansan, on the behavioral and psychological symptoms of dementia in patients with Alzheimer's disease2009
- Author(s)
  Hayashi Y, Ishida Y, Okahara K, Mitsuyama Y
- Organizer
  国際老年精神医学会
- Place of Presentation
  カナダモントリオール
- Data Source
  KAKENHI-PROJECT-21591524
[Presentation] A randomized, controlled comparative open label study of a traditional Japanese medicine, yokukansan, on the behavioral and psychological symptoms of dementia in patients with Alzheimer's disease2009
- Author(s)
  Hayashi Y, Ishida Y, Okahara K, Mitsuyama Y
- Organizer
  国際老年精神医学会
- Place of Presentation
  カナダモントリオール
- Data Source
  KAKENHI-PROJECT-21591524
[Presentation] Clioquinol itself does not inhibit Hydrogenperoxide formation induced by amyloid-beta peptide2006
- Author(s)
  Y. HAYASHI, Y. ISHIDA
- Organizer
  国際精神薬理学会
- Place of Presentation
  HIROSHIMA
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591298
[Presentation] Clioquinol itself does not inhibit Hydrogenperoxide formation induced by amyloid-beta peptide2006
- Author(s)
  Yoshihito, Hayashi, Yasushi, Ishida
- Organizer
  INTER NATIONAL PSYCHOPHARMACOLOGY
- Place of Presentation
  HIROSHIMA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591298
[Presentation] An open label study to investigate the effects of a traditional Japanese medicine, yokukansan, on the sleep disturbances in patients with Alzheimer’s disease and other dementia
- Author(s)
  Yoshihito Hayashi, Yasushi Ishida, Kazunori Okahara, Yoshio Mitsuyama
- Organizer
  Clinical Trials on Alzheimer's Disease (CTAD)
- Place of Presentation
  Philadelphia, USA
- Year and Date
  2014-11-20 – 2014-11-22
- Data Source
  KAKENHI-PROJECT-26461751

1. MATSUDA Kazanori (30311880)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. TASHIRO Kenichiro (00216954)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. EBIHARA Kousuke (20510720)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. HUNAHASHI Hideki (10404435)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. MITSUYAMA Yoshio (20112427)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. SAWADA Atsushi (10040247)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. UEDA Yuto (70244192)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. ISHIDA Yasushi (20212897)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

Hayashi Yoshihito 林 要人

HAYASHI Yoshihito 林 要人

Research Projects

Research Products

Co-Researchers

Biomarkers predict the occurrence of BPSDPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The efficacy of anti-Aβoligomer antibody to the toxicity of Aβto neuronal cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Free radical production from betaAmyloid oligomers and mechanism of neurotoxicity deduced from themPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Free -radical generation by amyloid p protein and the protective effect by laminin against amyloid β-protein induced toxicityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

βアミロイド凝集によるフリーラジカル発生と細胞毒性に関するin vitro研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Aralysis of laminin in brain as a inbibifor of βaryloidogenosis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Measuremrnt of laminins in cerebrospinal fluid (CSF) obtained from dementia using antibodies against laminin and laminin peptide -Developping a diagnostic biological marker-

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] 認知症の行動・心理症状に対する薬物療法の注意点─抑肝散の可能性─2017

Author(s)

Journal Title

Data Source

[Journal Article] An Open-label trial of Yokukansan on Sleep Disturbance in Alzheimer's disease and other Dementia2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] レビー小体型認知症患者に対する抑肝散投与の有用性 長期投与の有効性および安全性に関する後方視的観察研究2014

Author(s)

Journal Title

Data Source

[Journal Article] 認知症患者の行動・心理症状(BPSD)に対する抑肝散長期投与の安産性および有効性の検討2012

Author(s)

Journal Title

Data Source

[Journal Article] アルツハイマー型認知症の周辺症状(BPSD)に対する抑肝散の効果2010

Author(s)

Journal Title

Data Source

[Journal Article] Treatment of behavioral and psychological symptoms of Alzheimer-type dementia with Yokukansan in clinical practice2010

Author(s)

Journal Title

Data Source

[Journal Article] Effects of Yokukansan on behavioral and psychological symptoms of dementia in regular treatment for Alzheimer's disease2010

Author(s)

Journal Title

Data Source

[Journal Article] Treatment of behavioral and psychological symptoms of Alzheimer-type dementia with Yokukansan in clinical practice.2010

Author(s)

Journal Title

Data Source

Hayashi Yoshihito 林要人

HAYASHI Yoshihito 林要人

[Journal Article] レビー小体型認知症患者に対する抑肝散投与の有用性　長期投与の有効性および安全性に関する後方視的観察研究2014