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Ooi Jun  大井 淳

… Alternative Names

OOI Jun  大井 淳

大井 淳  オオイ ジュン

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Researcher Number 20302606
Other IDs
  • ORCIDhttps://orcid.org/0000-0001-8863-5040
Affiliation (Current) 2025: 帝京大学, 医療技術学部, 教授
Affiliation (based on the past Project Information) *help 2011: 東京大学, 医科学研究所, 助教
2007 – 2008: 東京大学, 医科学研究所, 助教
2001 – 2005: 東京大学, 医科学研究所, 助手
1999: 東京大学, 医科学研究所, 教務職員
Review Section/Research Field
Principal Investigator
Hematology / Hematology
Except Principal Investigator
Hematology / Hematology / General medical chemistry
Keywords
Principal Investigator
CD19 / リポソーム / Imatinib / ABL / BCR / 急性リンパ性白血病 / フィラデルフィア染色体 / STI571
Except Principal Investigator
白血病 / Adenovirus … More / 遺伝子治療 / GVHD / 臍帯血移植 / Random peptide-presenting phage library / Leukemia / CD4O ligand / Targeting / Cell therapy / Cancer immunology / Gene therapy / ランダムペプチド発現ファージ・ライブラリー / CD40リガンド / アデノウイルス / ターゲッティング / 細胞療法 / 癌免疫 / liposome / gene therapy / cytochrome C oxidase / antisense RNA / mitochondria / 抗腫瘍効果 / リボゾーム / アデノウィルス / アンチセンスRNA / チトクロームCオキシダーゼ / ミトコンドリア / 臍帯血 / VSEL / 間葉系幹細胞 / CD34陽性細胞 / ES細胞 / 組織幹細胞 / 臍帯 / 再生医療 / サイトカイン / 末梢血幹細胞移植 / 骨髄移植 / 同種移植 / MMP阻害剤 / マトリックスメタプロテアーゼ(MMP) / 繊維素溶解系 / 炎症性サイトカイン / 細胞動員 / プロセシング / VEGF / Kit-ligand / ニッチ細胞 / プラスミン / マトリックスメタロプロテイナーゼ / 血液線維素溶解系 / プラスミン阻害剤 / 線維素溶解系 / 血液凝固系 / マトリックスメタロプロテイナーゼ(MMP)造血ニッチ / 造血幹細胞移植学 / HLA-C / NK細胞受容体 / キラー免疫グロブリン様受容体 / 移植後免疫回復 / 白血病特異免疫 Less
  • Research Projects

    (7 results)
  • Research Products

    (38 results)
  • Co-Researchers

    (15 People)
  •  Functional differences between malignant niche on the process of leukemia/lymphoma progression and hematopoietic stem cell niche on the process of cord blood graft engraftment

    • Principal Investigator
      TAKAHASHI Satoshi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      The University of Tokyo
  •  Detection of VSEL cells in umbilical cord blood and development of co-culture system with umbilical cord-derived mesehchymal stem cells

    • Principal Investigator
      NAGAMURA Tokiko (INOUE Tokiko)
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      General medical chemistry
    • Research Institution
      The University of Tokyo
  •  Development of new strategy for cord blood transplantation using enhancedleukemia-specific immune response with donor T cell

    • Principal Investigator
      TAKAHASHI Satoshi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      The University of Tokyo
  •  フィラデルフィア染色体陽性急性リンパ性白血病の新規治療法の開発Principal Investigator

    • Principal Investigator
      大井 淳
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Hematology
    • Research Institution
      The University of Tokyo
  •  Development of cancer immunogene therapy with gene-modified adenoviral vector re-targeted by tumor-specific peptides

    • Principal Investigator
      TAKAHASHI Satoshi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      The University of Tokyo
  •  新規イムノリポソームを用いたフィラデルフィア染色体陽性急性リンパ性白血病の治療Principal Investigator

    • Principal Investigator
      大井 淳
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Hematology
    • Research Institution
      The University of Tokyo
  •  Feasibility of MARCO(Mitochondrial antisense RNA for cytochrome C Oxidase) for the treatment of leukerniaz

    • Principal Investigator
      SHIRATUJI Naoki
    • Project Period (FY)
      1999 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      Teikyo University School of Medicine
      The University of Tokyo

All 2011 2010 2009 2008 2007 2005 2004 Other

All Journal Article Presentation

  • [Journal Article] Incidence, risk factors and outcomes of bronchiolitis obliterans after allogeneic stem cell transplantation2011

    • Author(s)
      Nakaseko C, Ozawa S, Sakaida E, Sakai M, Kanda Y, Oshima K, Kurokawa M, Takahashi S, Ooi J, Shimizu T, Yokota A, Yoshiba F, Fujimaki K, Kanamori H, Sakai R, Saitoh T, Sakura T, Maruta A, Sakamaki H, Okamoto S
    • Journal Title

      Int J Hematol

      Volume: 93(3) Pages: 375-82

    • NAID

      10029534020

    • Data Source
      KAKENHI-PROJECT-21591234
  • [Journal Article] Unrelated cord blood transplantation after myeloablative conditioning in adults with advanced myelodysplastic syndromes2011

    • Author(s)
      Sato A, Ooi J, Takahashi S, Tsukada N, Kato S, Kawakita T, Yagyu T, Nagamura F, Iseki T, Tojo A, Asano S
    • Journal Title

      Bone Marrow Transplant

      Volume: 46(2) Pages: 257-61

    • Data Source
      KAKENHI-PROJECT-21591234
  • [Journal Article] Myeloablative unrelated cord blood transplantation for acute leukemia patients between 50 and 55 years of age : single institutional retrospective comparison with patients younger than 50 years of age2009

    • Author(s)
      Konuma T, Takahashi S, Ooi J, Tomonari A, Tsukada N, Kato S, Sato A, Monma F, Kasahara S, Nagamura-Inoue T, Uchimaru K, Iseki T, Tojo A, Yamaguchi T, Asano S
    • Journal Title

      Annals of Hematology

      Volume: 88(6) Pages: 581-8

    • Data Source
      KAKENHI-PROJECT-21591234
  • [Journal Article] Unrelated cord blood transplantation after myeloablative conditioning in adults with acute myelogenous leukemia2009

    • Author(s)
      Ooi J, Takahashi S, Tomonari A, Tsukada N, Konuma T, Kato S, KasaharaS, Sato A, Monma F, Nagamura F, Iseki T, Tojo A, Asano S
    • Journal Title

      Bone Marrow Transplant 43(6)

      Pages: 455-459

    • Data Source
      KAKENHI-PROJECT-19591098
  • [Journal Article] Second myeloablative allogeneic stem cell transplantation(SCT) using cord blood for leukemia relapsed after initial allogeneic SCT2009

    • Author(s)
      Konuma T, Ooi J, Takahashi S, Tomonari A, Tsukada N, Kato S, Sato A, Monma F, Kasahara S, Uchimaru K, Iseki T, Tojo A, Asano S
    • Journal Title

      Leuk Res

      Volume: 33(6) Pages: 840-2

    • Data Source
      KAKENHI-PROJECT-21591234
  • [Journal Article] Second myeloablative allogeneic stem cell transplantation(SCT)using cord blood for leukemia relapsed after initial allogeneic SCT.2009

    • Author(s)
      Konuma T, Ooi J, Takahashi S, et al.
    • Journal Title

      Leuk Res. 33

      Pages: 840-842

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591234
  • [Journal Article] Unrelated cord blood transplantation after myeloablative conditioning in adults with ALL2009

    • Author(s)
      Ooi J, Takahashi S, Tomonari A, Tsukada N, Konuma T, Kato S, Kasahara S, Sato A, Monma F, Nagamura F, Iseki T, Tojo A, Asano S
    • Journal Title

      Bone Marrow Transplant

      Volume: 43(6) Pages: 455-9

    • Data Source
      KAKENHI-PROJECT-21591234
  • [Journal Article] Second myeloablativeallogeneic stem cell transplantation (SCT) using cord blood for leukemia relapsedafter initial allogeneic SCT2009

    • Author(s)
      Konuma T, Ooi J, Takahashi S, Tomonari A, Tsukada N, Kato S, Sato A, Monma F, Kasahara S, Uchimaru K, IsekiT, Tojo A, Asano S.
    • Journal Title

      Leuk Res 33(6)

      Pages: 840-842

    • Data Source
      KAKENHI-PROJECT-19591098
  • [Journal Article] Donor cell-derived myelodysplastic syndrome after cord bloodtransplantation2009

    • Author(s)
      Konuma T, Ooi J, Takahashi S,Tomonari A, Tsukada N, Kato S, Sato A, Monma F, Hongo E, Uchimaru K, Tojo A,Asano S.
    • Journal Title

      Bone Marrow Transplant 43(5)

      Pages: 429-431

    • Data Source
      KAKENHI-PROJECT-19591098
  • [Journal Article] Myeloablative unrelated cord blood transplantation for acute leukemia patients between 50 and 55years of age : single institutional retrospective comparison with patients younger than 50years of age2009

    • Author(s)
      Konuma T, Ooi J, Takahashi S, et al.
    • Journal Title

      Ann Hematol 88

      Pages: 581-588

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591234
  • [Journal Article] YamaguchiT, Asano S. Myeloablative unrelated cordblood transplantation for acute leukemiapatients between 50 and 55 years of age : single institutional retrospective2009

    • Author(s)
      Konuma T, Takahashi S, Ooi J,Tomonari A, Tsukada N, Kato S, Sato A,Monma F, Kasahara S, Nagamura-Inoue T,Uchimaru K, Iseki T, Tojo A,
    • Journal Title

      comparison with patients younger than 50years of age. Ann Hematol 88(6)

      Pages: 581-588

    • Data Source
      KAKENHI-PROJECT-19591098
  • [Journal Article] Early renal injuryafter myeloablative cord blood transplantation in adults2008

    • Author(s)
      Mae H, Ooi J, Takahashi S, TomonariA, Tsukada N, Konuma T, Hongo E, KatoS, Kasahara S, Oiwa-Monna M, KurokawaY, Tojo A, Asano S
    • Journal Title

      LeukLymphoma 49(3)

      Pages: 538-42

    • Data Source
      KAKENHI-PROJECT-19591098
  • [Journal Article] Nakauchi H. Recipient-derived cells aftercord blood transplantation : dynamics elucidated by multicolor FACS, reflectinggraft failure and relapse2008

    • Author(s)
      Watanabe N, Takahashi S, Ishige M, Ishii Y, Ooi J, Tomonari A, Tsukada N, Konuma T, Kato S, Sato A, Tojo A
    • Journal Title

      Biol BloodMarrow Transplant 14(6)

      Pages: 693-701

    • Data Source
      KAKENHI-PROJECT-19591098
  • [Journal Article] Myeloablative unrelated cord bloodtransplantation for adult acute myeloid leukemia patients with 11q23abnormalities2008

    • Author(s)
      Konuma T, Ooi J, Takahashi S, Tomonari A, Tsukada N, Kato S, KasaharaS, Uchimaru K, Iseki T, Tojo A, Asano S.
    • Journal Title

      Eur J Haematol 80(6)

      Pages: 545-548

    • Data Source
      KAKENHI-PROJECT-19591098
  • [Journal Article] Unrelated cord blood transplantation after myeloablative conditioning in adults with acute myelogenous leukemia2008

    • Author(s)
      Ooi J, Takahashi S, Tojo A, et al
    • Journal Title

      Biol Blood Marrow Transplant 14(12)

      Pages: 1341-1347

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591098
  • [Journal Article] Central nervous system leukemia on magnetic resonanceimaging2008

    • Author(s)
      Konuma T, Ooi J, Takahashi S, Tomonari A, Tsukada N, Kato S, KasaharaS, Uchimaru K, Tojo A.
    • Journal Title

      Intern Med 47(5)

      Pages: 477-477

    • Data Source
      KAKENHI-PROJECT-19591098
  • [Journal Article] Impact of cytomegalovirus serostatus onoutcome of unrelated cord blood transplantation for adults : a single-institute 1experience in Japan2008

    • Author(s)
      Tomonari A, Takahashi S, Ooi J,Tsukada N, Konuma T, Kato S, KasaharaS, Iseki T, Yamaguchi T, Tojo A, Asano S
    • Journal Title

      Eur J Haematol 80(3)

      Pages: 251-257

    • Data Source
      KAKENHI-PROJECT-19591098
  • [Journal Article] Fatalacute tumor lysis syndrome followingintrathecal chemotherapy for acute lymphoblastic leukemia with meningealinvolvement2008

    • Author(s)
      Konuma T, Ooi J, Takahashi S, Tomonari A, Tsukada N, Kato S, Sato A, Monma F, Uchimaru K, Tojo A.
    • Journal Title

      Intern Med. 47(22)

      Pages: 1987-1988

    • Data Source
      KAKENHI-PROJECT-19591098
  • [Journal Article] Tsukada N, Konuma T, Kato S, KasaharaS, Iseki T, Tojo A, Asano S., Bloodeosinophilia after unrelated cord blood transplantation for adults2008

    • Author(s)
      Tomonari A, Takahashi S, Ooi J
    • Journal Title

      Bone MarrowTransplant 42(1)

      Pages: 63-65

    • Data Source
      KAKENHI-PROJECT-19591098
  • [Journal Article] Preemptive therapy with ganciclovir 5mg/kg once daily for cytomegalovirus infection after unrelated cord bloodtransplantation2008

    • Author(s)
      Tomonari A, Takahashi S, Ooi J,Tsukada N, Konuma T, Kobayashi T,Takasugi K, Iseki T, Tojo A, Asano S
    • Journal Title

      Bone Marrow Transplant 41

      Pages: 371-376

    • Data Source
      KAKENHI-PROJECT-19591098
  • [Journal Article] Nooccurrence of Pneumocystis jiroveci(carinii) pneumonia in 120 adults undergoing myeloablative unrelated cordblood transplantation2008

    • Author(s)
      Tomonari A, Takahashi S, Ooi J,Tsukada N, Konuma T, Kato S, KasaharaS, Iseki T, Tojo A, Asano S.
    • Journal Title

      Transpl Infect Dis 10(5)

      Pages: 303-307

    • Data Source
      KAKENHI-PROJECT-19591098
  • [Journal Article] Cardiovascular toxicity ofcryopreserved cord blood cell infusion.2008

    • Author(s)
      Konuma T, Ooi J, Takahashi S,Tomonari A, Tsukada N, Kobayashi T, Sato A, Kato S, Kasahara S, Ebihara Y, Nagamura-Inoue T, Tsuji K, Tojo A, Asano S
    • Journal Title

      Bone Marrow Transplant 41(10)

      Pages: 861-5

    • Data Source
      KAKENHI-PROJECT-19591098
  • [Journal Article] Cytogenetic remissions induced byinterferon alpha and imatinib mesylate areimmunologically distinct in chronic myeloid leukemia2007

    • Author(s)
      Nakayama S, Nagamura-Inoue T, Yokoyama K, Ohno N, Ooi J, TakahashiS, Uchimaru K, Iseki T, Tojo A
    • Journal Title

      Int J Hematol.Oct 86(3)

      Pages: 208-11

    • Data Source
      KAKENHI-PROJECT-19591098
  • [Journal Article] Comparative single-institute analysis ofcord blood transplantation from unrelateddonors with bone marrow or peripheralblood stem cell transplantation fromrelated donors in adult patients with hematological malignancies aftermyeloablative conditioning regimen2007

    • Author(s)
      Takahashi S, Ooi J, Tomonari A, Konuma T, Tsukada N, Oiwa-Monna M, Fukuno K, Uchiyama M, Takasugi K, Iseki T, Tojo A, Yamaguchi T, Asano S
    • Journal Title

      Blood 109(3)

      Pages: 1322-1330

    • Data Source
      KAKENHI-PROJECT-19591098
  • [Journal Article] Early-onsetpulmonary complication showing organizing pneumonia pattern followingcord blood transplantation in adults2007

    • Author(s)
      Tomonari A, Tsukada N, Takahashi S, Ooi J, Konuma T, Kobayashi T, Fukuno K,Takasugi K, Fujii T, Endo T, Iwamoto A, Oyaizu N, Tojo A, Asano S
    • Journal Title

      Int Jhematol 85(4)

      Pages: 364-366

    • Data Source
      KAKENHI-PROJECT-19591098
  • [Journal Article] Allogeneic stemcell transplantation for hepatosplenic gammadelta T-cell lymphoma2007

    • Author(s)
      Konuma T, Ooi J, Takahashi S, Tomonari A, Tsukada N, Kobayashi T,Sato A, Tojo A, Asano S
    • Journal Title

      LeukLymphoma 48(3)

      Pages: 630-632

    • Data Source
      KAKENHI-PROJECT-19591098
  • [Journal Article] Impact of ABO incompatibility onengraftment and transfusion requirementafter unrelated cord blood transplantation : a single institute experience in Japan.2007

    • Author(s)
      Tomonari A, Takahashi S, Ooi J,Tsukada N, Konuma T, Kobayashi T, SatoA, Iseki T, Yamaguchi T, Tojo A, Asano S.
    • Journal Title

      Bone Marrow Transplant 40(6)

      Pages: 523-528

    • Data Source
      KAKENHI-PROJECT-19591098
  • [Journal Article] Bacterial bloodstream infection inneutropenic adult patients after myeloablative cord blood transplantation : experience of a single institution in Japan2007

    • Author(s)
      Tomonari A, Takahashi S, Ooi J,Tsukada N, Konuma T, Kobayashi T, SatoA, Takasugi K, Iseki T, Tojo A, Asano S.
    • Journal Title

      Int J Hematol 85(3)

      Pages: 238-241

    • Data Source
      KAKENHI-PROJECT-19591098
  • [Journal Article] Unrelated cord blood transplantation after myeloablative conditioning for adult patients with refractory anemia2005

    • Author(s)
      Jun Ooi
    • Journal Title

      International Journal of Hematology 81

      Pages: 424-427

    • Data Source
      KAKENHI-PROJECT-15790489
  • [Journal Article] Unrelated cord blood transplantation for adult patients with de novo acute myeloid leukemia2004

    • Author(s)
      Jun Ooi
    • Journal Title

      Blood 103

      Pages: 489-491

    • Data Source
      KAKENHI-PROJECT-15790489
  • [Journal Article] CD19-targeting liposomes containing imatinib efficiently kill Philadelphia chromosome-positive acute lymphoblastic leukemia cells.2004

    • Author(s)
      Masamitsu Harata, Jun Ooi
    • Journal Title

      Blood 104

      Pages: 1442-1449

    • Data Source
      KAKENHI-PROJECT-15790489
  • [Journal Article] Unrelated cord blood transplantation for adult patients with acute lymphoblastic leukemia.2004

    • Author(s)
      Jun Ooi
    • Journal Title

      Leukemia 18

      Pages: 1905-1907

    • Data Source
      KAKENHI-PROJECT-15790489
  • [Journal Article] Unrelated cord blood transplantation after myeloablative conditioning in patients over the age of 45 years.2004

    • Author(s)
      Jun Ooi
    • Journal Title

      British Journal of Haematology 126

      Pages: 711-714

    • Data Source
      KAKENHI-PROJECT-15790489
  • [Journal Article] The efficacy of unrelated cord blood transplantation for adult myelodysplastic syndrome

    • Author(s)
      Jun Ooi
    • Journal Title

      Leukemia and Lymphoma (In press)

    • Data Source
      KAKENHI-PROJECT-15790489
  • [Presentation] Japan Cord Blood Bank Network. The role of G-CSF combination in conditioning regimen for CBT patients with AML Bone Marrow Transplant2011

    • Author(s)
      Takahashi S, Ooi J, Kato S, Kawakita T, Nakauchi Y, Monna M, Nagamura T, Kato K, Yamaguchi T., Asano S
    • Organizer
      第37回欧州造血細胞移植学会
    • Place of Presentation
      パリ
    • Data Source
      KAKENHI-PROJECT-21591234
  • [Presentation] Matched HLA Haplotype Contributes to Reduce Sever Acute GVHD with Conserving GVL Effect in HLA-Mismatched Cord Blood Transplantation2011

    • Author(s)
      Takahashi S, Ooi J, Kato S, Kawakita T, Tojo A, Ebihara Y, Mochizuki S, Yamamoto S, Tsuji K, Yamaguchi T, Morishima S, Morishima Y, Asano S
    • Organizer
      Blood 118(21): 1771. Abstr.# 4140, 53回アメリカ血液学会
    • Place of Presentation
      サンディエゴSan Diego Convention Center
    • Data Source
      KAKENHI-PROJECT-21591234
  • [Presentation] The impact of cytomegalovirus reactivation after cord blood transplantation in Adults2010

    • Author(s)
      Takahashi S, T. Yamaguchi, J. Ooi, N. Tsukada, S. Kato, T. Kawakita, T. Yagyu, M. Monna-ooiwa, A. Tojo, S. Asano
    • Organizer
      第36回欧州造血細胞移植学会
    • Place of Presentation
      ウィーン
    • Data Source
      KAKENHI-PROJECT-21591234
  • [Presentation] Impact of HLA Haplotype matching for mismatched cord blood transplantation2009

    • Author(s)
      Takahashi S, J. Ooi, N. Tsukada, S. Kato, A. Sato, T. Kawakita, Y. Nagata, M. Monna-ooiwa, A. Tojo, T. Yamaguchi, S. Morishima, Y. Morishima, S. Asano
    • Organizer
      Abstr.# 1206, 51回アメリカ血液学会
    • Place of Presentation
      ニューオーリンズ
    • Data Source
      KAKENHI-PROJECT-21591234
  • 1.  TAKAHASHI Satoshi (60226834)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 32 results
  • 2.  WATANABE Nobukazu (10334278)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 3.  KATO Kazunori (60233780)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 12 results
  • 4.  TOJO Arinobu (00211681)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 20 results
  • 5.  HATTORI Koichi (10360116)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  NAGAMURA Tokiko (70240736)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  ISHIGE Ikuo (30396957)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  KOBAYASHI Seiichiro (70376622)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  NAGAMURA Fumitaka (90282491)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  SHIRATUJI Naoki (00206301)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  MATSUDA Satoru (50242110)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  ASANO Shigetaka (50134614)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  佐藤 典治 (90162461)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  井関 徹 (10232365)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  GOTO Moritaka
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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