Arima Yoshimi 有馬好美

… Alternative Names

ARIMA Yoshimi 有馬好美

有馬好美アリマヨシミ

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Researcher Number	20309751
Other IDs
Affiliation (Current)	2025: 東京科学大学, 大学院医歯学総合研究科, 助教 2025: 藤田医科大学, 腫瘍医学研究センター, 客員准教授
Affiliation (based on the past Project Information) *help	2022: 藤田医科大学, がん医療研究センター, 客員准教授 2020 – 2021: 慶應義塾大学, 医学部(信濃町), 講師 2018: 慶應義塾大学, 医学部(信濃町), 専任講師 2018: 慶應義塾大学, 医学部(信濃町), 講師 2016 – 2017: 慶應義塾大学, 医学部(信濃町), 助教 2009 – 2015: Keio University, 医学部, 助教 2006: 千葉大, 薬学研究科(研究院), 助手
Review Section/Research Field	Principal Investigator General surgery / Basic Section 55010:General surgery and pediatric surgery-related / Pathological medical chemistry / Biological pharmacy
Keywords	Principal Investigator 乳がん / EMT / 癌 / がんの不均一性 / 不均一性 / 腫瘍内不均一性 / HER2 / 乳癌幹細胞 / 転移 / 再発 / 浸潤・転移 / Rb / 癌抑制遺伝子

Identification of tumor antigens that activate immune responses in heterogeneous breast cancersPrincipal Investigator
- Principal Investigator
  
  Arima Yoshimi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Fujita Health University
  Keio University
Cancer cell interaction mechanisms caused by the complexity of breast cancer tissuesPrincipal Investigator
- Principal Investigator
  
  Arima Yoshimi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Keio University
RNA Sequencing Analysis of Distant Metastasis of Breast Cancer CellsPrincipal Investigator
- Principal Investigator
  
  Arima Yoshimi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Keio University
Analysis of cancer stem cell properties andepithelial-mesenchymal transition signals in recurrence and metastasis of breast cancer cellsPrincipal Investigator
- Principal Investigator
  
  ARIMA Yoshimi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General surgery
- Research Institution
  Keio University
Significance of Rb pathway in the epithelial to mesenchymal transition inducing cancer invasion and metastasisPrincipal Investigator
- Principal Investigator
  
  ARIMA Yoshimi
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Keio University
チロシンキナーゼc-Ablの分裂期における新たな機能と発癌機構の解析Principal Investigator
- Principal Investigator
  
  有馬好美
- Project Period (FY)
  2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Chiba University

All 2023 2022 2021 2020 2018 2017 2016 2015 2014 2013 2012 2010 2009 Other

All Journal Article Presentation Patent

[Journal Article] Significance of Cancer-Associated Fibroblasts in the Interactions of Cancer Cells with the Tumor Microenvironment of Heterogeneous Tumor Tissue2023
- Author(s)
  Arima Yoshimi、Matsueda Satoko、Saya Hideyuki
- Journal Title
  
  Cancers
  
  Volume: 15 Issue: 9 Pages: 2536-2536
- DOI
  10.3390/cancers15092536
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08968
[Journal Article] Mutation of PTPN11 (Encoding SHP-2) Promotes MEK Activation and Malignant Progression in Neurofibromin-Deficient Cells in a Manner Sensitive to BRAP Mutation2022
- Author(s)
  Harigai Ritsuko、Sato Ryo、Hirose Chikako、Takenouchi Toshiki、Kosaki Kenjiro、Hirose Takanori、Saya Hideyuki、Arima Yoshimi
- Journal Title
  
  Cancers
  
  Volume: 14 Issue: 10 Pages: 2377-2377
- DOI
  10.3390/cancers14102377
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08968
[Journal Article] Pixel-Level Clustering of Hematoxylin?Eosin-Stained Sections of Mouse and Human Biliary Tract Cancer2022
- Author(s)
  Inoue Haruki、Aimono Eriko、Kasuga Akiyoshi、Tanaka Haruto、Iwasaki Aika、Saya Hideyuki、Arima Yoshimi
- Journal Title
  
  Biomedicines
  
  Volume: 10 Issue: 12 Pages: 3133-3133
- DOI
  10.3390/biomedicines10123133
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16006, KAKENHI-PROJECT-20K08968
[Journal Article] TGFβ Signaling Activated by Cancer-Associated Fibroblasts Determines the Histological Signature of Lung Adenocarcinoma2021
- Author(s)
  Sato Ryo、Imamura Kosuke、Semba Takashi、Tomita Yusuke、Saeki Sho、Ikeda Koei、Komohara Yoshihiro、Suzuki Makoto、Sakagami Takuro、Saya Hideyuki、Arima Yoshimi
- Journal Title
  
  Cancer Research
  
  Volume: 81 Issue: 18 Pages: 4751-4765
- DOI
  10.1158/0008-5472.can-20-3941
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H00518, KAKENHI-PROJECT-20K08968, KAKENHI-PROJECT-21K19416
[Journal Article] Oncogenic KRAS?expressing organoids with biliary epithelial stem cell properties give rise to biliary tract cancer in mice2021
- Author(s)
  Kasuga Akiyoshi、Semba Takashi、Sato Ryo、Nobusue Hiroyuki、Sugihara Eiji、Takaishi Hiromasa、Kanai Takanori、Saya Hideyuki、Arima Yoshimi
- Journal Title
  
  Cancer Science
  
  Volume: 印刷中 Issue: 5 Pages: 1822-1838
- DOI
  10.1111/cas.14703
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08968, KAKENHI-PROJECT-20H00518, KAKENHI-PROJECT-18K07243
[Journal Article] Molecular and cellular mechanisms underlying brain metastasis of breast cancer2020
- Author(s)
  Hosonaga Mari、Saya Hideyuki、Arima Yoshimi
- Journal Title
  
  Cancer and Metastasis Reviews
  
  Volume: 39 Issue: 3 Pages: 711-720
- DOI
  10.1007/s10555-020-09881-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08968, KAKENHI-PROJECT-20H00518
[Journal Article] Targeting of cancer stem cells by differentiation therapy2020
- Author(s)
  Arima Yoshimi、Nobusue Hiroyuki、Saya Hideyuki
- Journal Title
  
  Cancer Science
  
  Volume: 111 Issue: 8 Pages: 2689-2695
- DOI
  10.1111/cas.14504
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08968, KAKENHI-PROJECT-20H00518, KAKENHI-PROJECT-18K07243
[Journal Article] Lung Adenocarcinoma Mouse Models Based on Orthotopic Transplantation of Syngeneic Tumor-Initiating Cells Expressing EpCAM, SCA-1, and Ly6d2020
- Author(s)
  Semba Takashi、Sato Ryo、Kasuga Akiyoshi、Suina Kentaro、Shibata Tatsuhiro、Kohno Takashi、Suzuki Makoto、Saya Hideyuki、Arima Yoshimi
- Journal Title
  
  Cancers
  
  Volume: 12 Issue: 12 Pages: 3805-3805
- DOI
  10.3390/cancers12123805
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08968, KAKENHI-PROJECT-20H00518
[Journal Article] HER2 Heterogeneity Is Associated with Poor Survival in HER2-Positive Breast Cancer2018
- Author(s)
  Hosonaga Mari、Arima Yoshimi、Sampetrean Oltea、Komura Daisuke、Koya Ikuko、Sasaki Takashi、Sato Eiichi、Okano Hideyuki、Kudoh Jun、Ishikawa Shumpei、Saya Hideyuki、Ishikawa Takashi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 19 Issue: 8 Pages: 2158-2158
- DOI
  10.3390/ijms19082158
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10473
[Journal Article] Prospects for new lung cancer treatments that target EMT signaling2018
- Author(s)
  Otsuki Yuji、Saya Hideyuki、Arima Yoshimi
- Journal Title
  
  Developmental Dynamics
  
  Volume: 247 Issue: 3 Pages: 462-472
- DOI
  10.1002/dvdy.24596
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10473
[Journal Article] RNA Sequencing Analysis Reveals Interactions between Breast Cancer or Melanoma Cells and the Tissue Microenvironment during Brain Metastasis.2017
- Author(s)
  Sato R, Nakano T, Hosonaga M, Sampetrean O, Harigai R, Sasaki T, Koya I, Okano H, Kudoh J, Saya H, Arima Y.
- Journal Title
  
  Biomed Res Int.
  
  Volume: - Pages: 1-10
- DOI
  10.1155/2017/8032910
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K10473
[Journal Article] Development of mouse models of malignant phyllodes tumors by transplantation of syngeneic mammary gland cells expressing mutant H-Ras.2016
- Author(s)
  Takamoto Y, Arima Y, Saya H.
- Journal Title
  
  Genes Cells
  
  Volume: 21 Issue: 11 Pages: 1244-1252
- DOI
  10.1111/gtc.12435
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K10473
[Journal Article] Concise Review: Stem Cells and Epithelial-Mesenchymal Transition in Cancer: Biological Implications and Therapeutic Targets.2016
- Author(s)
  Sato R, Semba T, Saya H, Arima Y.
- Journal Title
  
  Stem Cells
  
  Volume: 34 Issue: 8 Pages: 1997-2007
- DOI
  10.1002/stem.2406
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K10473
[Journal Article] Expression of CD24 is associated with HER2 expression and supports HER2-Akt signaling in HER2-positive breast cancer cells.2014
- Author(s)
  Hosonaga M, Arima Y, Sugihara E, Kohno N and Saya H
- Journal Title
  
  Cancer Sci
  
  Volume: 105 Issue: 7 Pages: 779-787
- DOI
  10.1111/cas.12427
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22130007, KAKENHI-PROJECT-25461995, KAKENHI-PROJECT-25860245
[Journal Article] Ink4a/Arf –/– and HRAS(G12V) transform mouse mammary cells into triple-negative breast cancer containing tumorigenic CD49f – quiescent cells.2014
- Author(s)
  Kai K
- Journal Title
  
  Oncogene
  
  Volume: 33 Issue: 4 Pages: 440-448
- DOI
  10.1038/onc.2012.609
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001, KAKENHI-PROJECT-25461995, KAKENHI-PLANNED-22130007
[Journal Article] 乳がん幹細胞～HER2シグナルに関する新たな知見～2014
- Author(s)
  細永真理、有馬好美、佐谷秀行
- Journal Title
  
  腫瘍内科
  
  Volume: 第14巻3号 Pages: 281-7
- NAID
  40020220517
- Data Source
  KAKENHI-PROJECT-25461995
[Journal Article] Induction of ZEB Proteins by Inactivation of RB Protein Is Key Determinant of Mesenchymal Phenotype of Breast Cancer.2012
- Author(s)
  Arima Y,Hayashi H, Sasaki M, Hosonaga M, Goto TM, Chiyoda T, Kuninaka S, Shibata T, Ohata H, Nakagama H, Taya Y, Saya H
- Journal Title
  
  J Biol Chem
  
  Volume: 287 Pages: 7896-906
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791496
[Journal Article] Induction of ZEB Proteins by Inactivation of RB Protein Is Key Determinant of Mesenchymal Phenotype of Breast Cancer.2012
- Author(s)
  Arima Y, Hayashi H, Sasaki M, Hosonaga M, Goto TM, Chiyoda T, Kuninaka S, Shibata T, Ohata H, Nakagama H, Taya Y, Saya H.
- Journal Title
  
  J Biol Chem.
  
  Volume: 287(11) Pages: 7896-7906
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791496
[Journal Article] Loss of p16 expression is associated with the stem cell characteristics of surface markers and therapeutic resistance in estrogen receptor-negative breast cancer2012
- Author(s)
  Arima Y, Saya H, et al
- Journal Title
  
  InternationalJournal of Cancer
  
  Volume: 130 Issue: 11 Pages: 2568-2579
- DOI
  10.1002/ijc.26271
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650601, KAKENHI-PROJECT-23790376, KAKENHI-PROJECT-23791496
[Journal Article] Loss of p16 expression is associated with the stem cell characteristics of surface markers and therapeutic resistance in estrogen receptor-negative breast cancer2012
- Author(s)
  Arima Y, Hayashi N, Hayashi H, Sasaki M,Kai K, Abe E, Yoshida A, Mikami S, Nakamura S, and Saya H
- Journal Title
  
  Int J Cancer
  
  Volume: 130 Pages: 2568-79
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791496
[Journal Article] トリプルネガティブ乳癌におけるRb不活化と上皮間葉転換について2010
- Author(s)
  有馬好美、佐谷秀行
- Journal Title
  
  乳癌の臨床 Vol.25 No.6
  
  Pages: 617-621
- Data Source
  KAKENHI-PROJECT-21790326
[Journal Article] Breast cancer stem cells. (Review)2010
- Author(s)
  Kai K, Arima Y, Kamiya T, Saya H
- Journal Title
  
  Breast Cancer 17
  
  Pages: 80-85
- Data Source
  KAKENHI-PROJECT-21790326
[Journal Article] Decreased expression of neurofibromin contributes to epithelial-mesenchymal transition in neurofibromatosis type 1 (NF1).2010
- Author(s)
  有馬好美、林秀美、鎌田加奈子、後藤孝明、佐々木美香子、倉持朗、佐谷秀行
- Journal Title
  
  Experimental Dermatology
  
  Volume: Vol.19
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790326
[Journal Article] 神経線維腫形成の分子機構に対する新たな治療戦略の考案2010
- Author(s)
  有馬好美、佐谷秀行
- Journal Title
  
  日本レックリングハウゼン病学会雑誌第1巻第1号
  
  Pages: 11-15
- Data Source
  KAKENHI-PROJECT-21790326
[Journal Article] Decreased expression of neurofibromin contributes to epithelial-mesenchymal transition in neurofibromatosis type 1 (NF1).2010
- Author(s)
  Arima Y, Hayashi H, Kamata K, Goto T, Sasaki M, Kuramochi A, Saya H
- Journal Title
  
  Experimental Dermatology 19
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790326
[Journal Article] 上皮間葉転換ががんの浸潤転移に果たす役割2010
- Author(s)
  有馬好美、神谷敏夫、佐谷秀行
- Journal Title
  
  細胞工学別冊「がん転移臨床と研究の羅針盤」
  
  Pages: 166-169
- Data Source
  KAKENHI-PROJECT-21790326
[Journal Article] Breast cancer stem cells.2010
- Author(s)
  甲斐千晴、有馬好美、神谷敏夫、佐谷秀行
- Journal Title
  
  Breast Cancer
  
  Volume: Vol.17 Pages: 80-85
- NAID
  10027255296
- Data Source
  KAKENHI-PROJECT-21790326
[Journal Article] 上皮間葉転換ががんの浸潤転移に果たす役割2010
- Author(s)
  有馬好美、神谷敏夫、佐谷秀行
- Journal Title
  
  細胞工学
  
  Volume: 別冊 Pages: 166-169
- Data Source
  KAKENHI-PROJECT-21790326
[Journal Article] トリプルネガティブ乳癌におけるRb不活化と上皮間葉転換について2010
- Author(s)
  有馬好美、佐谷秀行
- Journal Title
  
  乳癌の臨床
  
  Volume: Vol.25 Pages: 617-621
- Data Source
  KAKENHI-PROJECT-21790326
[Journal Article] Breast cancer stem cells.2010
- Author(s)
  甲斐千晴、有馬好美、神谷敏夫、佐谷秀行
- Journal Title
  
  Breast Cancer Vol.17
  
  Pages: 80-85
- NAID
  10027255296
- Data Source
  KAKENHI-PROJECT-21790326
[Journal Article] 神経線維腫形成の分子機構に対する新たな治療戦略の考案2010
- Author(s)
  有馬好美、佐谷秀行
- Journal Title
  
  日本レックリングハウゼン病学会雑誌
  
  Volume: 第1巻 Pages: 11-15
- Data Source
  KAKENHI-PROJECT-21790326
[Journal Article] Decreased expression of neurofibromin contributes to epithelial-mesenchymal transition in neurofibromatosis type 1(NF1).2009
- Author(s)
  有馬好美、林秀美、鎌田加奈子、後藤孝明、佐々木美香子、倉持朗、佐谷秀行
- Journal Title
  
  Experimental Dermatology
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790326
[Journal Article] Maintenance of HCT116 colon cancer cell line conforms to a stochastic model but not a cancer stem cell model.2009
- Author(s)
  Kai K, Nagano O, Sugihara E, Arima Y, Sampetrean O, Ishimoto T, Nakanishi M, Ueno N, Iwase H, Saya H
- Journal Title
  
  Cancer Science 100
  
  Pages: 2275-2282
- NAID
  10027197873
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790326
[Journal Article] 上皮間葉転換と癌浸潤転移2009
- Author(s)
  有馬好美、神谷敏夫、佐谷秀行
- Journal Title
  
  細胞工学 Vol.28
  
  Pages: 655-658
- Data Source
  KAKENHI-PROJECT-21790326
[Journal Article] 上皮間葉転換と癌浸潤転移2009
- Author(s)
  有馬好美、神谷敏夫、佐谷秀行
- Journal Title
  
  細胞工学 Vol.28 No.7
  
  Pages: 655-658
- Data Source
  KAKENHI-PROJECT-21790326
[Patent] 癌組織の不均一性マーカー及びその使用2016
- Inventor(s)
  佐谷秀行、有馬好美、千場　隆
- Industrial Property Rights Holder
  佐谷秀行、有馬好美、千場　隆
- Industrial Property Rights Type
  特許
- Filing Date
  2016-06-30
- Data Source
  KAKENHI-PROJECT-16K10473
[Patent] 癌組織の不均一性マーカー及びその使用2016
- Inventor(s)
  佐谷秀行、有馬好美、千場　隆
- Industrial Property Rights Holder
  佐谷秀行、有馬好美、千場　隆
- Industrial Property Rights Type
  特許
- Filing Date
  2016
- Acquisition Date
  2017
- Data Source
  KAKENHI-PROJECT-16K10473
[Patent] 癌組織の不均一性マーカー及びその利用2015
- Inventor(s)
  有馬好美、佐谷秀行
- Industrial Property Rights Holder
  学校法人慶應義塾
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2015-133033
- Filing Date
  2015-07-01
- Data Source
  KAKENHI-PROJECT-25461995
[Presentation] CDK4/6阻害剤によるがん細胞制御2022
- Author(s)
  有馬好美
- Organizer
  第30回日本乳癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08968
[Presentation] PTPN11変異はRas/MAPK経路を活性化してNF1欠損細胞の悪性進行をもたらし、BRAP変異によって抑制される2022
- Author(s)
  有馬好美
- Organizer
  第13回日本レックリングハウゼン病学会学術大会
- Data Source
  KAKENHI-PROJECT-20K08968
[Presentation] Approach to identifying the molecular mechanisms of refractory heterogeneous cancers based on mouse models2021
- Author(s)
  有馬好美
- Organizer
  第80回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08968
[Presentation] CDK4/6阻害剤によるがん細胞制御2021
- Author(s)
  有馬好美
- Organizer
  第18回日本臨床腫瘍学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08968
[Presentation] Heterogeneous Tumors Composed of Epithelial-type and Mesenchymal-type Breast Cancer Cells2018
- Author(s)
  Yoshimi Arima
- Organizer
  第７７回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-16K10473
[Presentation] Intratumor Heterogeneity and Cancer Promotion2017
- Author(s)
  Yoshimi Arima
- Organizer
  第７６回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-16K10473
[Presentation] Intra-tumor Heterogeneity Associated with EMT Contributes to the Progression of Cancer2017
- Author(s)
  Yoshimi Arima, Hideyuki Saya
- Organizer
  Gordon Research Conference, Cell Growth & Proliferation
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10473
[Presentation] Tumor Heterogeneity Associated with EMT Contributes to the Progression of Breast Cancer2016
- Author(s)
  有馬好美
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-06
- Invited
- Data Source
  KAKENHI-PROJECT-16K10473
[Presentation] がん細胞間相互作用とintra-tumor heterogeneity2016
- Author(s)
  有馬好美
- Organizer
  第24回日本乳癌学会学術総会
- Place of Presentation
  東京ビッグサイト（東京都江東区）
- Year and Date
  2016-06-16
- Invited
- Data Source
  KAKENHI-PROJECT-16K10473
[Presentation] The Cancer Promoting Mechanism Driven by Intra-tumor Heterogeneity2016
- Author(s)
  Arima Y, Semba T, Kasuga A, Harigai R and Saya H
- Organizer
  Tenth AACR-JCA Joint Conference
- Place of Presentation
  マウイ（アメリカ）
- Year and Date
  2016-02-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461995
[Presentation] Intratumor Heterogeneity in Triple-Negative Breast Cancer2015
- Author(s)
  有馬好美
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25461995
[Presentation] トリプルネガティブ乳がんにおけるintra-tumor heterogeneity2015
- Author(s)
  有馬好美
- Organizer
  第23回日本乳癌学会
- Place of Presentation
  東京国際フォーラム（東京都千代田区）
- Year and Date
  2015-07-02
- Data Source
  KAKENHI-PROJECT-25461995
[Presentation] CD24 promotes HER2 signaling pathways and CD24 inhibition sensitizes anti-HER2 therapy in breast cancer2014
- Author(s)
  Yoshimi Arima, Mari Hosonaga, Hideyuki Saya
- Organizer
  The AACR Annual Meeting 2014
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-25461995
[Presentation] Significance of RB-ZEB axis in EMT phenotype of breast cancer and inhibition of ZEB by CDK4/6 inhibitor2013
- Author(s)
  Yoshimi Arima, Mari Hosonaga, Hideyuki Saya
- Organizer
  The 2013 San Antonio Breast Cancer Symposium
- Place of Presentation
  San Antonio, USA
- Data Source
  KAKENHI-PROJECT-25461995
[Presentation] The epithelial-mesenchymal transition-related transcription factor ZEB suppresses Claudin expression in breast cancer cells2013
- Author(s)
  Yoshimi Arima, Mari Hosonaga, Hideyuki Saya
- Organizer
  The AACR Annual Meeting 2013
- Place of Presentation
  Washington, USA
- Data Source
  KAKENHI-PROJECT-25461995
[Presentation] がん細胞におけるCDK4/6の役割とCDK4/6阻害剤の抗がん剤としての可能性について2013
- Author(s)
  有馬好美、佐谷秀行
- Organizer
  第17回日本がん分子標的治療学会
- Place of Presentation
  京都
- Invited
- Data Source
  KAKENHI-PROJECT-25461995
[Presentation] The role of CDK4/6 in cancer cells and the potential therapeutic effects of CDK4/6 inhibitors.2012
- Author(s)
  Arima Y, Hosonaga M, Sugihara E and Saya H
- Organizer
  2012 Annual Meeting of the American Society for Cell Biology
- Place of Presentation
  San Francisco,CA, USA
- Data Source
  KAKENHI-PROJECT-23791496
[Presentation] The role of CDK4/6 in cancer cells and the potential therapeutic effects of CDK4/6 inhibitors2012
- Author(s)
  Arima Yand Saya H
- Organizer
  The 17th Japan-Korea Cancer Research Workshop
- Place of Presentation
  Busan, Korea
- Data Source
  KAKENHI-PROJECT-23791496
[Presentation] The role of CDK4/6 in cancer cells and the potential therapeutic effects of CDK4/6 inhibitors.2012
- Author(s)
  Yoshimi Arima
- Organizer
  The 17th Japan-Korea Cancer Research Workshop
- Place of Presentation
  Busan, Korea
- Data Source
  KAKENHI-PROJECT-23791496
[Presentation] Significance of EMT in breast cancer cells2010
- Author(s)
  有馬好美、佐谷秀行
- Organizer
  第69回日本癌学会
- Place of Presentation
  大阪国際会議場、リーガロイヤルホテル大阪(大阪府)
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-21790326
[Presentation] トリプルネガティブ乳癌におけるRb不活化と上皮間葉転換誘導因子ZEBの発現について2010
- Author(s)
  Arima Y, Saya H
- Organizer
  第18回日本乳癌学会(シンポジウム口頭発表)
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-21790326
[Presentation] Significance of EMT in breast cancer cells2010
- Author(s)
  Arima Y, Saya H
- Organizer
  第69回日本癌学会(シンポジウム口頭発表)
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21790326
[Presentation] トリプルネガティブ乳癌におけるRb不活化と上皮間葉転換誘導因子ZEBの発現について2010
- Author(s)
  有馬好美、佐谷秀行
- Organizer
  第18回日本乳癌学会
- Place of Presentation
  ロイトン札幌他(北海道)
- Year and Date
  2010-06-24
- Data Source
  KAKENHI-PROJECT-21790326
[Presentation] 癌におけるRb 不活化に基づく上皮間葉転換(EMT)誘導2009
- Author(s)
  Arima Y, Saya H
- Organizer
  第82回日本生化学会大会(シンポジウム口頭発表)
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21790326
[Presentation] 癌におけるRb不活化に基づく上皮間葉転換(EMT)誘導2009
- Author(s)
  有馬好美、佐谷秀行
- Organizer
  日本生化学会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2009-10-21
- Data Source
  KAKENHI-PROJECT-21790326
[Presentation] 神経線維腫形成の分子機構2009
- Author(s)
  Arima Y
- Organizer
  第1回日本レックリングハウゼン病学会学術大会(教育講演口頭発表)
- Place of Presentation
  東京慈恵会医科大学
- Year and Date
  2009-11-15
- Data Source
  KAKENHI-PROJECT-21790326
[Presentation] The development of malignant phyllodes tumor models.
- Author(s)
  Takamoto Y, Arima Y and Saya H
- Organizer
  The 2014 San Antonio Breast Cancer Symposium
- Place of Presentation
  San Antonio, TX, USA
- Year and Date
  2014-12-09 – 2014-12-13
- Data Source
  KAKENHI-PROJECT-25461995
[Presentation] CD24 promotes HER2 signaling pathway and CD24 inhibition sensitizes anti-HER2 therapy in breast cancer.
- Author(s)
  Arima Y, Hosonaga M and Saya H
- Organizer
  American Association for Cancer Research Annual Meeting 2014
- Place of Presentation
  San Diego, CA, USA
- Year and Date
  2014-04-05 – 2014-04-09
- Data Source
  KAKENHI-PROJECT-25461995
[Presentation] Effect of HER2 overexpression on cancer stem-like characteristics of triple-negative breast cancer cells.
- Author(s)
  Hosonaga M, Arima Y and Saya H
- Organizer
  European Society for Medical Oncology (ESMO) 2014 Congress
- Place of Presentation
  Madrid, Spain
- Year and Date
  2014-09-26 – 2014-09-30
- Data Source
  KAKENHI-PROJECT-25461995
[Presentation] Expression of CD24 Supports HER2-Akt Signaling in HER2-Positive Breast Cancer Cells.
- Author(s)
  Arima Y, Hosonaga M, Saya H
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25461995

1. 佐谷秀行

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
2. 春日章良

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Arima Yoshimi 有馬 好美

ARIMA Yoshimi 有馬 好美

有馬 好美 アリマ ヨシミ

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Identification of tumor antigens that activate immune responses in heterogeneous breast cancersPrincipal Investigator

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Cancer cell interaction mechanisms caused by the complexity of breast cancer tissuesPrincipal Investigator

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RNA Sequencing Analysis of Distant Metastasis of Breast Cancer CellsPrincipal Investigator

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Analysis of cancer stem cell properties andepithelial-mesenchymal transition signals in recurrence and metastasis of breast cancer cellsPrincipal Investigator

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Significance of Rb pathway in the epithelial to mesenchymal transition inducing cancer invasion and metastasisPrincipal Investigator

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チロシンキナーゼc-Ablの分裂期における新たな機能と発癌機構の解析Principal Investigator

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[Journal Article] Significance of Cancer-Associated Fibroblasts in the Interactions of Cancer Cells with the Tumor Microenvironment of Heterogeneous Tumor Tissue2023

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[Journal Article] Mutation of PTPN11 (Encoding SHP-2) Promotes MEK Activation and Malignant Progression in Neurofibromin-Deficient Cells in a Manner Sensitive to BRAP Mutation2022

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[Journal Article] Pixel-Level Clustering of Hematoxylin?Eosin-Stained Sections of Mouse and Human Biliary Tract Cancer2022

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[Journal Article] TGFβ Signaling Activated by Cancer-Associated Fibroblasts Determines the Histological Signature of Lung Adenocarcinoma2021

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[Journal Article] Oncogenic KRAS?expressing organoids with biliary epithelial stem cell properties give rise to biliary tract cancer in mice2021

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[Journal Article] Molecular and cellular mechanisms underlying brain metastasis of breast cancer2020

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[Journal Article] Targeting of cancer stem cells by differentiation therapy2020

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[Journal Article] Lung Adenocarcinoma Mouse Models Based on Orthotopic Transplantation of Syngeneic Tumor-Initiating Cells Expressing EpCAM, SCA-1, and Ly6d2020

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Arima Yoshimi 有馬好美

ARIMA Yoshimi 有馬好美

有馬好美アリマヨシミ