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Ohshima Toshio  大島 登志男

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… Alternative Names

大島 登志男  オオシマ トシオ

OOSHIMA Toshio  大島 登志男

大島 登志雄  オオシマ トシオ

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Researcher Number 20311334
Other IDs
Affiliation (Current) 2025: 早稲田大学, 理工学術院, 教授
Affiliation (based on the past Project Information) *help 2025: 早稲田大学, 理工学術院, 教授
2018 – 2023: 早稲田大学, 理工学術院, 教授
2014 – 2016: 早稲田大学, 理工学術院, 教授
2008 – 2011: 早稲田大学, 理工学術院, 教授
2007: The Institute of Physical and Chemical Research, Laboratory for Developmental Neurobiology, Visiting Researcher … More
2007: 理化学研究所, 発生神経生物研究チーム, 副チームリーダー
2007: The Institute of Physical and Chemical Research, 発生神経生物研究チーム, 客員研究員
2006: 横浜市立大学, 理化学研究所・発生神経生物研究チーム, 副チームリーダー
2004 – 2006: 独立行政法人理化学研究所, 発生神経生物研究チーム, 副チームリーダー
2005: 理化学研究所, 発生神経生物研究チーム, 副チームリーダー
2003: 独立行政法人理化学研究所, 発生神経生物研究チーム, 研究員
1999 – 2000: 理化学研究所, 発生神経生物研究チーム, 研究員 Less
Review Section/Research Field
Principal Investigator
Basic Section 46020:Anatomy and histopathology of nervous system-related / Neurochemistry/Neuropharmacology / Nerve anatomy/Neuropathology / Biological Sciences / Nerve anatomy/Neuropathology
Except Principal Investigator
Medium-sized Section 52:General internal medicine and related fields / Biological Sciences
Keywords
Principal Investigator
Dab1 / Cdk5 / 神経再生 / リン酸化 / キナーゼ / CRMP / stathmin / GSK3β / 脊髄損傷 / コンディショナルKO … More / Reelin / セリン・スレオニンキナーゼ / 神経回路形成 / 神経損傷 / モデルマウス / パーキンソン病 / マウスモデル / 神経変性疾患 / MS analysis / mutant mice / 2D-DIGE / proteomics / protein phosphorvlation / 変異マウス / 質量分析 / 2次元電気泳動 / プロテオーム解析 / タンパク質リン酸化 / Alzheimer's disease / tubulin / cyclin-dependent kinase / threonine kinase / serine / phosphorylation / 細胞移動 / 大脳皮質 / アルツハイマー病 / リーリン / チュブリン / サイクリン依存性キナーゼ / 神経発達 / 神経発生 / スパイン形成 / 樹状突起形成 / 大脳皮質形成 / LTD / LTP / CaMKII / tamoxifen / Cre recombinase / マウス / mouse / neuron / migration / kinase / Pak1 / p35 / 神経特異的 … More
Except Principal Investigator
Th17細胞 / 甲状腺ホルモン / Eomes陽性Th細胞 / EAE / 神経・内分泌・免疫制御 / 神経・免疫・内分泌連関 / 中枢神経慢性炎症 / 神経・免疫・内分泌相関 / 内分泌性制御因子 / Eomes+ Th細胞 / プロラクチン / 環境因子 / 内分泌性免疫制御因子 / 免疫性神経疾患 / ノックアウトマウス / 軸索ガイダンス / 皮質 / 細胞移動 / Slit / Vab-8 / axonal transport / UNC-51 / Netrin / Sema3A / 軸索ガイダンス分子 / 組織構築 / 神経ガイダンス / プレキシン / セマフォリン / CRMP Less
  • Research Projects

    (11 results)
  • Research Products

    (53 results)
  • Co-Researchers

    (14 People)
  •  神経炎症とCRMPの関連の解明と神経疾患治療への応用Principal Investigator

    • Principal Investigator
      大島 登志男
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 46020:Anatomy and histopathology of nervous system-related
    • Research Institution
      Waseda University
  •  Study on the role of CRMP2 phosphorylation in neural circuit formation and regenerationPrincipal Investigator

    • Principal Investigator
      大島 登志男
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 46020:Anatomy and histopathology of nervous system-related
    • Research Institution
      Waseda University
  •  Study to develop therapeutic strategy of neurodegenerative disorders by targeting on CRMPPrincipal Investigator

    • Principal Investigator
      Ohshima Toshio
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 46020:Anatomy and histopathology of nervous system-related
    • Research Institution
      Waseda University
  •  Cross-talk between endocrine and environmental factors in neuroimmune disorders

    • Principal Investigator
      Yamamura Takashi
    • Project Period (FY)
      2018 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 52:General internal medicine and related fields
    • Research Institution
      National Center of Neurology and Psychiatry
  •  Elucidation of roles of CRMP in neural circuit formation and regeneration and application for the treatment of spinal cord injuryPrincipal Investigator

    • Principal Investigator
      Ohshima Toshio
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Nerve anatomy/Neuropathology
    • Research Institution
      Waseda University
  •  Functional analysis of Cdk5 by using conditional KO of its activating subunit p35Principal Investigator

    • Principal Investigator
      OHSHIMA Toshio
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Waseda University
  •  誘導型コンディショナルKOを用いたCdk5の脳機能における役割の解明Principal Investigator

    • Principal Investigator
      大島 登志男
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The Institute of Physical and Chemical Research
  •  Proteomics of phospho-proteins during brain development using mutant micePrincipal Investigator

    • Principal Investigator
      OHSHIMA Toshio
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      The Institute of Physical and Chemical Research
  •  The role of CRMP family proteins in the establishment of neural tissue architectures

    • Principal Investigator
      GOSHIMA Yoshio
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Yokohama City University
  •  Identification and functional analysis of Cdk5-mediated phosphorylation of the proteins that are related to brain formation and developmentPrincipal Investigator

    • Principal Investigator
      OHSHIMA Toshio
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      RIKEN
  •  神経特異的サイクリン依存性キナーゼ(cdk5)の個体レベルでの機能解析Principal Investigator

    • Principal Investigator
      大島 登志男
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Nerve anatomy/Neuropathology
    • Research Institution
      The Institute of Physical and Chemical Research

All 2024 2022 2020 2019 2017 2016 2015 2014 2012 2011 2010 2009 2007 2006 2005

All Journal Article Presentation Book

  • [Book] 神経特異的キナーゼCdk5の神経発達と神経変性への関与. Brain Science Review 20102010

    • Author(s)
      大島登志男
    • Publisher
      クバプロ
    • Data Source
      KAKENHI-PROJECT-21500356
  • [Journal Article] Drug Treatment Attenuates Retinal Ganglion Cell Death by Inhibiting Collapsin Response Mediator Protein 2 Phosphorylation in Mouse Models of Normal Tension Glaucoma2024

    • Author(s)
      Wang Yuebing、Brahma Musukha Mala、Takahashi Kazuya、Hernandez Alessandra Nolia Blanco、Ichikawa Koki、Minami Syuntaro、Goshima Yoshio、Harada Takayuki、Ohshima Toshio
    • Journal Title

      NeuroMolecular Medicine

      Volume: 26 Issue: 1 Pages: 13-13

    • DOI

      10.1007/s12017-024-08778-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K06464, KAKENHI-PROJECT-21K18279, KAKENHI-PROJECT-21H02819
  • [Journal Article] Genetic inhibition of collapsin response mediator protein‐2 phosphorylation ameliorates retinal ganglion cell death in normal‐tension glaucoma models2022

    • Author(s)
      Brahma Musukha Mala、Takahashi Kazuya、Namekata Kazuhiko、Harada Takayuki、Goshima Yoshio、Ohshima Toshio
    • Journal Title

      Genes to Cells

      Volume: 27 Issue: 8 Pages: 526-536

    • DOI

      10.1111/gtc.12971

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K18279, KAKENHI-PROJECT-19KK0229, KAKENHI-PROJECT-21H02819, KAKENHI-PROJECT-20K07751, KAKENHI-PROJECT-22K06464
  • [Journal Article] Loss of Collapsin Response Mediator Protein 4 Attenuates 6-Hydroxydopamine-Induced Impairments in a Mouse Model of Parkinson’s Disease2020

    • Author(s)
      Li Wenting、Goshima Yoshio、Ohshima Toshio
    • Journal Title

      Neurochemical Research

      Volume: 45 Issue: 10 Pages: 2286-2301

    • DOI

      10.1007/s11064-020-03086-z

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K06511
  • [Journal Article] Lanthionine ketimine ester improves outcome in an MPTP-induced mouse model of Parkinson's disease via suppressions of CRMP2 phosphorylation and microglial activation2020

    • Author(s)
      Togashi Kentaro、Hasegawa Masaya、Nagai Jun、Kotaka Ken、Yazawa Arina、Takahashi Miyuki、Masukawa Daiki、Goshima Yoshio、Hensley Kenneth、Ohshima Toshio
    • Journal Title

      Journal of the Neurological Sciences

      Volume: 413 Pages: 116802-116802

    • DOI

      10.1016/j.jns.2020.116802

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K06511
  • [Journal Article] Genetic suppression of CRMP2 phosphorylation improves outcome in MPTP-induced Parkinson’s model mice2019

    • Author(s)
      Togashi K, Hasegawa M, Nagai J, Tonouchi A, Masukawa D, Hensley K, Goshima Y, Ohshima T.
    • Journal Title

      Genes to Cells

      Volume: 24 Issue: 1 Pages: 31-40

    • DOI

      10.1111/gtc.12651

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06511
  • [Journal Article] Genetic inhibition of CRMP2 phosphorylation delays Wallerian degeneration after optic nerve injury2019

    • Author(s)
      Kinoshita Y, Kondo S, Takahashi K, Nagai J, Wakatsuki S, Araki T, Goshima Y, Ohshima T
    • Journal Title

      BBRC

      Volume: 514 Issue: 4 Pages: 1037-1039

    • DOI

      10.1016/j.bbrc.2019.05.060

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K06511, KAKENHI-PROJECT-17K19945
  • [Journal Article] Genetic inhibition of CRMP2 phosphorylation at serine 522 promotes axonal regeneration after optic nerve injury2019

    • Author(s)
      Kondo S, Takahashi K, Kinoshita Y, Nagai J, Wakatsuki S, Araki T, Goshima Y, Ohshima T
    • Journal Title

      Sci Rep

      Volume: 9 Issue: 1 Pages: 7188-7188

    • DOI

      10.1038/s41598-019-43658-w

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06511, KAKENHI-PROJECT-17K19945
  • [Journal Article] Lanthionine ketimine ester promotes locomotor recovery after spinal cord injury by reducing neuroinflammation and promoting axon growth2017

    • Author(s)
      Kotaka K, Nagai J, Hensley K, Ohshima T
    • Journal Title

      BBRC

      Volume: 483 Issue: 1 Pages: 759-764

    • DOI

      10.1016/j.bbrc.2016.12.069

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26430043
  • [Journal Article] CRMP1 and CRMP4 are required for proper orientation of dendrites of cerebral pyramidal neurons in the developing mouse brain2017

    • Author(s)
      Takaya R, Nagai J, Piao W. Niisato E, Nakabayashi T, Yamazaki Y, Nakamura F, Yamashita N, Kolattukudy P. Goshima Y, Ohshima T
    • Journal Title

      Brain Res

      Volume: 1655 Pages: 161-167

    • DOI

      10.1016/j.brainres.2016.11.003

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26430043
  • [Journal Article] Inhibition of CRMP2 phosphorylation repairs CNS by regulating neurotrophic and inhibitory responses.2016

    • Author(s)
      Nagai, J., Owada, K., Kitamura, Y., Goshima, Y., Ohshima, T.
    • Journal Title

      Exp Neurol

      Volume: 277 Pages: 283-95

    • DOI

      10.1016/j.expneurol.2016.01.015

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-13J05321, KAKENHI-PROJECT-26430043
  • [Journal Article] Deletion of Crmp4 attenuates CSPG-induced inhibition of axonal growth and induces nociceptive recovery after spinal cord injury.2016

    • Author(s)
      Nagai J, Takaya R, Piao W, Goshima Y, Ohshima T.
    • Journal Title

      Mol Cell Neurosci.

      Volume: 74 Pages: 42-48

    • DOI

      10.1016/j.mcn.2016.03.006

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-13J05321, KAKENHI-PROJECT-26430043
  • [Journal Article] Phosphorylation of CRMP2 by Cdk5 regulates dendritic spine development of cortical neuron in the mouse hippocampus2016

    • Author(s)
      Jin X, Sasamoto K, Nagai J, Yamazaki Y, Saito K, Goshima Y, Inoue T, Ohshima T.
    • Journal Title

      Neural Plasticity

      Volume: - Pages: 1-7

    • DOI

      10.1155/2016/6790743

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26430043
  • [Journal Article] Crmp4 deletion promotes recovery from spinal cord injury by neuroprotection and limited scar formation.2015

    • Author(s)
      Nagai, J., Kitamura, Y., Owada, K., Yamashita, N., Takei, K., Goshima, Y., Ohshima, T.
    • Journal Title

      Sci. Rep.

      Volume: 5 Issue: 1 Pages: 8269-8269

    • DOI

      10.1038/srep08269

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-13J05321, KAKENHI-PUBLICLY-26111718, KAKENHI-PROJECT-26290024, KAKENHI-PROJECT-26430043
  • [Journal Article] Phosphorylation of CRMP2 is involved in proper dendritic field organization2012

    • Author(s)
      Yamashita N, Ohshima T, Goshima Y., et al
    • Journal Title

      J.Neurosci.

      Volume: 32 Pages: 1360-1365

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500356
  • [Journal Article] Phosphorylation of CRMP2 is involved in proper dendritic field organization2012

    • Author(s)
      Yamashita N, Ohshima T, Nakamura F, Kolattukudy P, Honnorat J, Mikoshiba K, Goshima Y
    • Journal Title

      J. Neurosci

      Volume: 32 Pages: 1360-1365

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500356
  • [Journal Article] Hypomyelination Phenotype Caused by Impaired Differentiation of Oligodendrocytes in Emx1-cre Mediated Cdk5 Conditional Knockout Mice2011

    • Author(s)
      He X, Takahashi S, Suzuki H, Hashikawa, T, Kulkarni AB, Mikoshiba K, Ohshima T
    • Journal Title

      Neurochem Res

      Volume: 36 Pages: 1293-1303

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500356
  • [Journal Article] Hypomyelination phenotype caused by impaired differentiation of oligodendrocytes in Emxlcre mediated Cdk5 conditional knockout mice2011

    • Author(s)
      He X, Takahashi S, Ohshima T., et al
    • Journal Title

      Neurochem Res

      Volume: 36 Pages: 1293-1303

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500356
  • [Journal Article] Phosphorylation of AATYK1 by Cdk5 suppresses its tyrosine phosphorylation2010

    • Author(s)
      Tsutsumi K, Takano T, Endo R, Fukuda M, Ohshima T, Tomomura M, Hisanaga S
    • Journal Title

      PLoS ONE

      Volume: 5(4)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500356
  • [Journal Article] Commitment of 1-methyl-4-phenylpyrinidinium ion-induced neuronal cell death by proteasome-mediated degradation of p35 Cyclin-dependent kinase 5 activator2009

    • Author(s)
      Endo R, Saito T, Asada A, Kawahara H, Ohshima T, Hisanaga S
    • Journal Title

      J. Biol. Chem

      Volume: 284 Pages: 26029-39

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500356
  • [Journal Article] Increased proximal bifurcation of CA1 pyramidal apical dendrites in sema3A mutant mice.2009

    • Author(s)
      Nakamura F, Ugajin K, Yamashita N, Okada T, Uchida Y, Taniguchi M, Ohshima T, Goshima Y.
    • Journal Title

      J Comp Neurol 516

      Pages: 360-375

    • Data Source
      KAKENHI-PROJECT-17082006
  • [Journal Article] Semaphorin3A signaling mediated by Fyn-dependent tyrosine phosphorylation of collapsin response mediator protein 2 at tyrosine 32.2009

    • Author(s)
      Uchida Y, Ohshima T, Yamashita N, Ogawara M, Sasaki Y, Nakamura F, Goshima Y.
    • Journal Title

      J Biol Chem. 284(40)

      Pages: 27393-27401

    • Data Source
      KAKENHI-PROJECT-17082006
  • [Journal Article] Increased proximal bifurcation of CA1 pyramidal apical dendrites in sema3A mutant mice2009

    • Author(s)
      Nakamura F, Ugajin K, Yamashita N, Okada T, Uchida Y, Taniguchi M, Ohshima T, Goshima Y
    • Journal Title

      J. Comp. Neurol

      Volume: 516 Pages: 360-375

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500356
  • [Journal Article] Conditional deletion of neuronal cyclin-dependent kinase 5 in developing forebrain results in microglial activation and neurodegeneration2009

    • Author(s)
      Takahashi S, Ohshima T, Hirasawa M, Pareek TK, Bugge TH, Morozov A, Fujieda K, Brady RO, Kulkarni AB
    • Journal Title

      American J. Pathology

      Volume: 176 Pages: 320-329

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500356
  • [Journal Article] Semaphorin3A signaling mediated by Fyn-dependent tyrosine phosphorylation of collapsin response mediator protein 2 at tyrosine 32.2009

    • Author(s)
      Uchida Y, Ohshima T, Yamashita N, Ogawara M, Saski Y, Nakamura F, Goshima Y.
    • Journal Title

      J Biol Chem 284

      Pages: 27393-27401

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17082006
  • [Journal Article] Increased proximal bifurcation of CA1 pyramidal apical dendrites in sema3A mutant mice.2009

    • Author(s)
      Nakamura F, Ugajin K, Yamashita N, Okada T, Uchida Y, Taniguchi M, Ohshima T, Goshima Y.
    • Journal Title

      J Comp Neuro1 516

      Pages: 360-375

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17082006
  • [Journal Article] Cdk5 is required for multipolar-to-bipolar transition during radial neuronal migration and proper dendrite development of pyramidal neurons in the cerebral cortex.2007

    • Author(s)
      Toshio Ohshima
    • Journal Title

      Development 134

      Pages: 2273-2282

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18022050
  • [Journal Article] Regulation of spine development by semaphorin3A through cyclin-dependent kinase 5 phosphorylation of collapsin response mediator protein 1.2007

    • Author(s)
      Yamashita N, Morita A, Uchida Y, Nakamura F, Usui H, Ohshima T, Taniguchi M, Honnorat J, Thomasset N, Takei K, Takahashi T, Kolattukudy P, Goshima Y.
    • Journal Title

      J Neuroscience 27

      Pages: 12546-12554

    • Data Source
      KAKENHI-PROJECT-17082006
  • [Journal Article] Regulation of spine development by semaphorin3A through cyclin-dependent kinase 5 phosphorylation of collapsin response mediator protein 1.2007

    • Author(s)
      Yamashita N, Morita A, Uchida Y, Nakamura F, Usui H, Ohshima T, Taniguchi M, Honnorat J, Thomasset N, Takei K, Takahashi T, Kolattukudy P, Goshima Y.
    • Journal Title

      J Neuroscience 27巻46号

      Pages: 12546-54

    • Data Source
      KAKENHI-PROJECT-17082006
  • [Journal Article] Modulation of Reelin signaling by Cyclin-dependent kinase 52007

    • Author(s)
      Toshio Ohshima
    • Journal Title

      Brain Res. 1140

      Pages: 84-95

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18500305
  • [Journal Article] Modulation of Reeling signaling by Cyclin-dependent kinase 52007

    • Author(s)
      Toshio Ohshima
    • Journal Title

      Brain Res. 1140

      Pages: 84-95

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18500305
  • [Journal Article] Modulation of Reelin signaling by Cyclin-dependent kinase 52006

    • Author(s)
      T.Ohshimaら
    • Journal Title

      Brain Research (in press)

    • Data Source
      KAKENHI-PROJECT-15500273
  • [Journal Article] Modulation of Reelin signaling by Cyclin-dependent kinase 5.2006

    • Author(s)
      Ohshima, T., Suzuki, H., Morimura, T., Ogawa, M., Mikoshiba, K.
    • Journal Title

      Brain Res. (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15500273
  • [Journal Article] Phosphorylation of the tubulin binding protein, stathmin by Cdk5 and MAP kinase in the brain.2006

    • Author(s)
      Hayashi, K., Pan, Y., Shu, H., Ohshima, T., Kansy, W. J., White, CL., Tamminga, C. A., Sobel, A., Curmi, P. A., Mikoshiba, K., Bibb J. A.
    • Journal Title

      J. Neurochem. 99

      Pages: 237-250

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18500305
  • [Journal Article] Collapsin response mediator protein 1 mediates reelin signaling in cortical neuronal migration.2006

    • Author(s)
      Yamashita N, Uchida Y, Ohshima T, Hirai S, Nakamura F, Taniguchi M, Mikoshiba K, Honnorat J, Kolattukudy P, Thomasset N, Takei K, Takahashi T, Goshima Y
    • Journal Title

      J Neurosci 26・51

      Pages: 13357-13362

    • Data Source
      KAKENHI-PROJECT-17082006
  • [Journal Article] Modulation of Reelin signaling by Cyclin-dependent kinase 52006

    • Author(s)
      T.Ohshima ら
    • Journal Title

      Brain Reserch (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15500273
  • [Journal Article] Collapsin Response Mediator Protein 1 Mediates Reelin Signaling in Cortical Neuronal Migration.2006

    • Author(s)
      Yamashita N, Uchida Y, Ohshima T, Hirai S, Nakamura F, Taniguchi M, Mikoshiba K, Honnorat J, Kolattukudy P, Thomasset N, Takei K, Takahashi T, Goshima Y.
    • Journal Title

      J. Neurosci. 26

      Pages: 13357-13362

    • Data Source
      KAKENHI-PROJECT-17082006
  • [Journal Article] Semaphorin-3A signaling is mediated via sequential Cdk5-GSK3β phosphorylation of CRMP2 : implication of common phosphorylating mechanism underlying axon guidance and Alzheimer's disease.2005

    • Author(s)
      Uchida, Y., Ohshima, T., Sasaki, Y., Suzuki, H., Yanai, S., Yamashita, N., Nakamura, F., Takei, K., Ihara, Y., Mikoshiba, K., Kolattukudy, P., Honnorat, J., Goshima, Y.
    • Journal Title

      Genes to Cells 10

      Pages: 165-179

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15500273
  • [Journal Article] Impairment of hippocampal long-term depression and defective spatial learning and memory in p35 mice2005

    • Author(s)
      T.Ohshimaら
    • Journal Title

      J.Neurochem. 94

      Pages: 917-925

    • Data Source
      KAKENHI-PROJECT-15500273
  • [Journal Article] Impairment of hippocampal long-term depression and defective spatial learning and memory in p35 mice.2005

    • Author(s)
      Ohshima, T., Ogura, H., Tomizawa, K., Hayashi, K., Suzuki, H., Saito, T., Kamei, H., Nishi, A., Bibb, J.A., Hisanaga, S, Matsui, H., Mikoshiba, K.
    • Journal Title

      J Neurochem. 94

      Pages: 917-925

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15500273
  • [Journal Article] Impairment of hippocampal long-term depression and defective spatial learning and memory in p35 mice2005

    • Author(s)
      T.Ohshima ら
    • Journal Title

      J. Neurochem. 94

      Pages: 917-925

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15500273
  • [Presentation] ランチオニンケチミンエステルによる神経炎症抑制と軸索伸長を介した脊髄損傷後の後肢運動機能の向上2016

    • Author(s)
      小高 謙, Kenneth Hensley, 大島 登志男
    • Organizer
      第39回日本分子生物学年会
    • Place of Presentation
      横は野
    • Data Source
      KAKENHI-PROJECT-26430043
  • [Presentation] Dephosphorylation of CRMP2 enhances recovery after spinal cord injury2015

    • Author(s)
      Jun Nagai, Kazuki Owada, Yoshiteru Kitamura, Yoshio Goshima, Toshio Ohshima
    • Organizer
      SfN Annual Meeting “Neuroscience 2015"
    • Place of Presentation
      シカゴ・USA
    • Year and Date
      2015-10-20
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26430043
  • [Presentation] CRMP2 dephosphorylation induces locomotor and sensory recovery after spinal cord injury2015

    • Author(s)
      Jun Nagai, Kazuki Owada, Yoshiteru Kitamura, Yoshio Goshima, Toshio Ohshima
    • Organizer
      BMB2015
    • Place of Presentation
      神戸
    • Year and Date
      2015-12-10
    • Data Source
      KAKENHI-PROJECT-26430043
  • [Presentation] Genetic modifications of Crmp enhance axonal regrowth after spinal cord injury by reducing cytoskeletal destabilization and inflammatory responses2014

    • Author(s)
      J. Nagai, Y. Kitamura, K. Owasa, Y. Goshima, T. Ohshima
    • Organizer
      SFN Neuroscience meeting 2014
    • Place of Presentation
      Washijgton D.C., USA
    • Year and Date
      2014-11-18
    • Data Source
      KAKENHI-PROJECT-26430043
  • [Presentation] Collapsin response mediator proteins regulate bifurcation of apical dendrites in hippocampal CA1 pyramidal neurons during the brain development2011

    • Author(s)
      Niisato E, Nagai, J, Yamashita N, Nakamura F, Goshima Y, and Ohshima T
    • Organizer
      2011 SFN annual meeting
    • Place of Presentation
      Washington DC, USA
    • Year and Date
      2011-11-13
    • Data Source
      KAKENHI-PROJECT-21500356
  • [Presentation] Role of collapsin response mediator proteins for dendritic development in hippocampal CA1 pyramidal neurons2010

    • Author(s)
      Niisato E, Yamashita N, Nakamura F, Goshima Y, Ohshima T
    • Organizer
      Neuro 2010
    • Data Source
      KAKENHI-PROJECT-21500356
  • [Presentation] Hypomyelination phenotype caused by impaired differentiation of oligodendrocytes in Emx1-cre mediated Cdk5 conditional knockout mice2010

    • Author(s)
      He X, Takahashi S, Suzuki H, Hashikawa T, Kulkarni AB, Mikoshiba K, Ohshima T
    • Organizer
      BMB 2010
    • Place of Presentation
      Kobe, Japan
    • Year and Date
      2010-12-07
    • Data Source
      KAKENHI-PROJECT-21500356
  • [Presentation] Sema3A regulates apical dendritic growth of hippocampal CA1 pyramidal neurons2009

    • Author(s)
      Nakamura F, Ugajin N, Yamashita M, Taniguchi M, Ohshima T, Goshima Y
    • Organizer
      32th Japan Neuroscience Society Meeting
    • Place of Presentation
      東京
    • Year and Date
      2009-09-16
    • Data Source
      KAKENHI-PROJECT-17082006
  • [Presentation] Cdk5 is required for multipolar-to-bipolar transition during radial neuronal migration in the cerebral cortex.2007

    • Author(s)
      Toshio Ohshima
    • Organizer
      Neuro2007
    • Place of Presentation
      Yokohama
    • Year and Date
      2007-09-10
    • Data Source
      KAKENHI-PROJECT-18022050
  • [Presentation] CRMP1 regulates spine maturation through mediating Semaphorin3A signaling in vivo.2007

    • Author(s)
      Yamashita N, Morita A, Uchida Y, Ohshima T, Nakamura F, Usui H, Honnorat J, Kolattukudy P, Thomasset N, Goshima Y
    • Organizer
      Annual Meeting of the Society for Neuroscience
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-17082006
  • [Presentation] Role of Cdk5 in brain development and function2007

    • Author(s)
      Ohshima T.
    • Organizer
      Croucher Symposium The Roles of Cdk5 in Neuronal development, Synaptic Plasticity & Neurodegenerative diseases
    • Place of Presentation
      HongKong, China
    • Year and Date
      2007-01-09
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18500305
  • [Presentation] Role of Cdk5 in brain development and function2007

    • Author(s)
      Toshio Ohshima
    • Organizer
      Croucher Symposium "The Roles of Cdk5 in Neuronal development, Synaptic Plasticity & Neurodegenerative diseases"
    • Place of Presentation
      Hong Kong, China
    • Year and Date
      2007-01-09
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18500305
  • 1.  GOSHIMA Yoshio (00153750)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 10 results
  • 2.  Yamamura Takashi (90231670)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  中村 史雄 (10262023)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 10 results
  • 4.  鈴木 厚 (00264606)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  大木 伸司 (50260328)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  北條 浩彦 (60238722)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  林 幼偉 (80392439)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  佐藤 和貴郎 (90469990)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  服部 正平 (70175537)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  土居 芳充 (20597174)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  NAGAI Jun
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 12.  内田 穣
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  原田 高幸
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 14.  行方 和彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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