YASUMOTO Hiroaki 安本博晃

Researcher Number	20314750
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2007 – 2008: Hiroshima University, Graduate School of Biomedical Sciences, Assistant Professor 2002 – 2004: Hiroshima University, Graduate School of Biomedical Sciences, Research Associate, 大学院・医歯薬学総合研究科, 助手 2000 – 2001: 広島大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Urology Except Principal Investigator Urology / Urology
Keywords	Principal Investigator 前立腺癌 / SDF1 / CXCR4 / ケモカインレセプター / ケモカイン / 遠隔転移 / クロストーク / 線細芽細胞成長因子受容体 / アンドロゲンレセプター / クロス・トーク / 線維芽細胞成長因子受容体 … More Except Principal Investigator … More 遺伝子治療 / 前立腺癌 / FGFR2IIIb / Gene therapy / 分化誘導 / アポトーシス / 放射線治療 / 増殖抑制 / チロシンキナーゼ / Guanine nucleotide binding protein / prostate cancer / ヒト前立腺癌 / Hormone independent / ホルモン不応性 / 線維芽細胞成長因子受容体 / 分化 / FGFR / 線維芽細胞成長因子 / DNA methylation / transcriptional factor / androgen receptor / RIZ 1 / nuclear receptor / p53 / DNAメチル化 / 転写因子 / アンドロゲンレセプター / RIZ1 / 核内受容体 / Radiation / Prostate cancer / Differentiation / Growth inhibition / Tyrosine kinase / Fibroblast growth factor receptor / Fibroblast growth factor / MAP kinase / 遺伝子変異 / MAP Kinase / FRS2 / FGFR2 / 線維芽細胞受容体 / Chemotherapy / Radiotherapy / Apoptosis / 上皮・間質相互作用 / 遺伝子移入 / 腫瘍抑制 / 化学療法 / gene therapy / differentiation / growth inhibition / tyrosine kinase / fibroblast growth factor receptor / fibroblast growth factor / サイトケラチン / ラクトフェリン / Apolosis / Signal pathway / FRS2 phosphorilation / Androgen Receptor / FGFR2IIIb gene / クロストーク / HGF受容体 / FGFR2IIIb遺伝子 / シグナル伝達経路 / FRS2りん酸化 / アンドロゲン受容体 / FDFR2 b遺伝子 / ホルモン不応性前立腺癌 Less

Implication of FGFR in loss of hormone dependency of prostate cancer and its application to new therapy for prostate cancer
- Principal Investigator
  
  MATSUBARA Akio
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Hiroshima University
Clinical application and functional analysis of the cofactor of androgen receptor in prostate cancer
- Principal Investigator
  
  USUI Tsuguru
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Hiroshima University
Development of new therapy for hormone independent prostate cancer.
- Principal Investigator
  
  USUI Tsuguru
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  HIROSHIMA UNIVERSITY
FGFR2 gene mutation in human prostate cancer : Close relation to loss of hormone dependency and therapeutic application
- Principal Investigator
  
  MATSUBARA Akio
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  HIROSHIMA UNIVERSITY
前立腺癌の遠隔転移におけるケモカインレセプターの関与Principal Investigator
- Principal Investigator
  
  安本博晃
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Urology
- Research Institution
  Hiroshima University
Study on molecular mechanism of the development in hormone independence of human prostate carcinoma and application for new therapy.
- Principal Investigator
  
  USUI Tsugurun
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  HIROSHIMA UNIVERSITY
Basic research on novel therapy for hormone-refractory prostate cancer with tyrosine kinase
- Principal Investigator
  
  MATSUBARA Akio
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  HIROSHIMA UNIVERSITY
前立腺癌細胞の増殖における性ホルモンと成長因子受容体のクロス・トークPrincipal Investigator
- Principal Investigator
  
  安本博晃
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Urology
- Research Institution
  Hiroshima University

All 2009 2007 2004

All Journal Article Presentation

[Journal Article] Restoration of FGF receptor type 2 enhances radiosensitivity of hormone-refractory human prostate carcinoma PC-3 cells2009
- Author(s)
  Matsubara Akio, Teishima Jun, Mirkhat Suichinov, Yasumoto Hiroaki, Seki Mitsuhiro
- Journal Title
  
  Anticancer Res 21
  
  Pages: 2141-2146
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591852
[Journal Article] GNL3L inhibits activity of estrogen-related receptor gamma by competing for coactivator binding2007
- Author(s)
  Hiroaki, Yasumoto, Lingjun, Meng, Tao, Lin, Qubo, Zhu, Robert, Y.L.,Tsai
- Journal Title
  
  Journal Cell Science 120
  
  Pages: 2532-2543
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591755
[Journal Article] GNL3L inhibits activity of estrogen-related receptor gamma by competing for coactivator binding2007
- Author(s)
  Hiroaki Yasumoto
- Journal Title
  
  Journal Cell Science 120
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591755
[Journal Article] Insulin-like growth factor binding protein-related protein 1 (IGFBP-rP1) has potential tumour-suppressive activity in human lung cancer2007
- Author(s)
  Yuan, Chen, Fei, Ye, Manuela, Pacyna-Gengelbach, Thomas, Knosel, Nicole, Deutschmann, Per, Lund, Hiroaki, Yasumoto, Tsuguru, Usui, Iver, Petersen
- Journal Title
  
  Journal of Pathology 211(4)
  
  Pages: 431-8
- NAID
  120000875406
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591755
[Journal Article] GNL3L inhibits activity of estrogen-related receptor gamma by competing for coactivator binding2007
- Author(s)
  YASUMOTO HIROAKI
- Journal Title
  
  J Cell Sci 120
  
  Pages: 2532-2543
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591755
[Journal Article] Lower urinary tract symptoms after radical perineal prostatectomy2007
- Author(s)
  Akio, Matsuhara, Tatsuaki, Yoneda, Hiroaki, Yasumoto, Jun, Teishima, Hiroaki, Shiina, Mikio, Igawa, Koji, Mita, Tsuguru, Usui
- Journal Title
  
  Japanese Journal of Clinical Oncology 37(7)
  
  Pages: 534-539
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591755
[Journal Article] Restoration of Fibroblast Growth Factor Receptor 2 Suppresses Growth and Tumorigenicity of Malignant Human Prostate Carcinoma PC-3 Cells.2004
- Author(s)
  Hiroaki Yasumoto
- Journal Title
  
  Prostate 61(3)
  
  Pages: 236-242
- NAID
  110004632657
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591690
[Journal Article] Restoration of Fibroblast Growth Factor Receptor 2 Suppresses Growth and Tumorigenicity of Malignant Human Prostate carcinoma PC-3 Cells.2004
- Author(s)
  Hiroaki Yasumoto
- Journal Title
  
  Prostate 61(3)
  
  Pages: 236-242
- NAID
  110004632657
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591690
[Journal Article] Restoration of Fibroblast Growth Factor Receptor 2 Suppresses Growth and Tumorigenicity of Malignant Human Prostate Carcinoma PC-3 Cells.2004
- Author(s)
  Hiroaki Yasumoto
- Journal Title
  
  Prostate 61(3)
  
  Pages: 236-242
- NAID
  110004632657
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591689
[Journal Article] Restoration of Fibroblast Growth Factor Receptor 2 Suppresses Growth and Tumorigenicity of Malignant Human Prostate Carcinoma PC-3 Cells2004
- Author(s)
  Hiroaki Yasumoto
- Journal Title
  
  Tte Prostate 61・3
  
  Pages: 236-242
- NAID
  110004632657
- Data Source
  KAKENHI-PROJECT-15591689
[Presentation] Guanine nucleotide binding protein-like 3はestrogen-related receptor γの転写活性を阻害する2007
- Author(s)
  安本博晃
- Organizer
  第15回日本ステロイドホルモン学会学術集会
- Place of Presentation
  仙台
- Year and Date
  2007-11-24
- Data Source
  KAKENHI-PROJECT-19591852
[Presentation] Guanine nucleotide binding protein like 3はestrogen-related receptor γの転写活性を阻害する2007
- Author(s)
  安本博晃
- Organizer
  第15回日本ステロイドホルモン学会学術集会
- Place of Presentation
  仙台
- Year and Date
  2007-11-24
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591755
[Presentation] Guanine nucleotide binding protein like 3はestrogen-related receptorγの転写活性を阻害する2007
- Author(s)
  安本博晃
- Organizer
  第15回日本ステロイドホルモン学会学術集会
- Place of Presentation
  仙台
- Year and Date
  2007-11-24
- Data Source
  KAKENHI-PROJECT-18591755
[Presentation] Guanine nucleotide binding protein like 3 inhibits the transcriptional activity of estrogen-related receptor γ2007
- Author(s)
  HIROAKI, YASUMOTO
- Organizer
  15th Annual Meeting of the Japanese Steroid Association
- Place of Presentation
  Sendai Japan
- Year and Date
  2007-11-24
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591755
[Presentation] Guanine nucleotide binding protein-like 3 はestrogen-related receptorγの転写活性を阻害する2007
- Author(s)
  安本博晃
- Organizer
  第15回日本ステロイドホルモン学会学術集会
- Place of Presentation
  仙台市
- Year and Date
  2007-11-24
- Data Source
  KAKENHI-PROJECT-19591852

1. MATSUBARA Akio (10239064)

# of Collaborated Projects: 6 results

# of Collaborated Products: 1 results
2. USUI Tsugurun (30034060)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
3. MITA Koji (70304425)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. TEISHIMA Jun (20397962)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
5. KAMIYA Kenji (60116564)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. MUTAGUCHI Kazuaki (00314758)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. HASEGAWA Yasuhisa (90403568)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. OHARA Shinya (70444693)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. SEKI Mitsuhiro (80372697)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. HAYASHI Tetsutaro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

YASUMOTO Hiroaki 安本 博晃

Research Projects

Research Products

Co-Researchers

Implication of FGFR in loss of hormone dependency of prostate cancer and its application to new therapy for prostate cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Clinical application and functional analysis of the cofactor of androgen receptor in prostate cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of new therapy for hormone independent prostate cancer.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

FGFR2 gene mutation in human prostate cancer : Close relation to loss of hormone dependency and therapeutic application

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

前立腺癌の遠隔転移におけるケモカインレセプターの関与Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on molecular mechanism of the development in hormone independence of human prostate carcinoma and application for new therapy.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Basic research on novel therapy for hormone-refractory prostate cancer with tyrosine kinase

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

前立腺癌細胞の増殖における性ホルモンと成長因子受容体のクロス・トークPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Restoration of FGF receptor type 2 enhances radiosensitivity of hormone-refractory human prostate carcinoma PC-3 cells2009

Author(s)

Journal Title

Data Source

[Journal Article] GNL3L inhibits activity of estrogen-related receptor gamma by competing for coactivator binding2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] GNL3L inhibits activity of estrogen-related receptor gamma by competing for coactivator binding2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Insulin-like growth factor binding protein-related protein 1 (IGFBP-rP1) has potential tumour-suppressive activity in human lung cancer2007

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] GNL3L inhibits activity of estrogen-related receptor gamma by competing for coactivator binding2007

Author(s)

Journal Title

Data Source

[Journal Article] Lower urinary tract symptoms after radical perineal prostatectomy2007

Author(s)

Journal Title

Description

YASUMOTO Hiroaki 安本博晃