YAMAUCHI Junji 山内淳司

… Alternative Names

山内淳司ヤマウチジユンジ

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Researcher Number	20335483
Other IDs	https://orcid.org/0000-0002-3618-998X
Affiliation (Current)	2025: 東京薬科大学, 生命科学部, 教授 2025: 国立研究開発法人国立成育医療研究センター, 薬剤治療研究部, 室長
Affiliation (based on the past Project Information) *help	2017 – 2020: 東京薬科大学, 生命科学部, 教授 2016: 国立研究開発法人国立成育医療研究センター, 薬剤治療研究部, 室長 2015 – 2016: 国立研究開発法人国立成育医療研究センター, その他部局等, その他 2009 – 2014: National Research Institute for Child Health and Development, 薬剤治療研究部, 室長 2013: 独立行政法人国立成育医療研究センター, 室長 … More 2005 – 2009: 国立成育医療センター(研究所), 薬剤治療研究部, 室長 2003: 奈良先端科技大, 助手 2002: 奈良先端科学技術大学院大学, バイオサイエンス研究科, 助手 Less
Review Section/Research Field	Principal Investigator Neurochemistry/Neuropharmacology / Neurochemistry/Neuropharmacology / Neurochemistry/Neuropharmacology / Biological Sciences / Functional biochemistry Except Principal Investigator Biological pharmacy
Keywords	Principal Investigator 低分子量GTP結合蛋白質 / 脱ミエリン現象 / 創薬標的分子 / 交換因子 / シグナル伝達 / ミエリン形成 / ミエリン / キナーゼ / ミエリン化 / ミエリン形成促進 … More / 創薬標的 / 脱髄 / 髄鞘 / シグナル伝達分子 / サイトヘジン / 治療標的分子 / 遺伝子改変動物 / MAPキナーゼ / 脱ミエリン / 末梢神経 / 共培養 / 神経栄養因子 / シュワン細胞 / 維持 / 遺伝子改変マウス / インビトロ共培養システム / 変性疾患 / ホメオスタシス / アダプター分子 / 受容体 / ミエリン再生 / 再生医療 / カプリゾン / オリゴデンドログリア細胞 / 再ミエリン化 / 恒常性 / 大脳白質変性症 / オリゴデンドロサイト / ミエリン再編 / ミエリン維持 / モデル動物 / モデル組織 / 脱ミエリンンの改善 / 脳白質変性症 / PMD / PLP1 / Pelizaeus-Merzbacher / 治療標的候補分子 / 創薬標的候補分子 / シグナル伝達因子 / ミエリン形成の促進 / ミエリン形成の抑制 / ミエリン発生 / Rhoファミリー / Arfファミリー / GTPアーゼ活性化蛋白質 / 脱髄改善 / 髄鞘形成 / 髄鞘発生 / 発生プログラム / 再生プログラム / 障害後再生 / 増殖因子受容体 / ミエリン形成抑制 / 創薬 / 髄鞘髄鞘 / ACAP2 / サイトヘジン2 / サイトヘジン1 / 脱ミエリン疾患 / Arf6 / 促進シグナル / 抑制シグナル / 組織形成 / 神経細胞 / 分子標的治療 / RNA干渉 / 髄鞘化 / 脱随疾患 / ノックダウンマウス / セリン・スレオニンキナーゼ / チロシンキナーゼ / 脱ミエリン化 / 人工組織構築 / グリア細胞 / 先天性疾患 / 標的分子 / 分子メカニズム / PMP22 / 脱髄疾病 / 分子神経生物学 / 分子神経科学 / 細胞遊走 / DRG神経細胞 / JNK / Srcファミリーキナーゼ / RhoファミリーGTP結合蛋白質 / グアニンヌクレオチド交換因子 / G蛋白質シグナル / 細胞増殖抑制 … More Except Principal Investigator 発生 / 脳・神経 / シグナル伝達 / 細胞・組織 Less

Signaling mechanism for myelin maintenancePrincipal Investigator
- Principal Investigator
  
  Junji Yamauchi
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Tokyo University of Pharmacy and Life Science
脱ミエリン病で特異的に活性化される分子経路を抑制することで、病態を改善する試みPrincipal Investigator
- Principal Investigator
  
  山内淳司
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  National Center for Child Health and Development
Negative regulation of axonal myelinationPrincipal Investigator
- Principal Investigator
  
  Yamauchi Junji
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  National Center for Child Health and Development
A search of novel molecular mechanisms regulating neural progenitor cell proliferation in the cerebral cortex
- Principal Investigator
  
  KATOH Hironori
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biological pharmacy
- Research Institution
  Kyoto University
Evaluation of a drug-target-molecule for demyelinating disorders using Dock7 knockdown mousePrincipal Investigator
- Principal Investigator
  
  YAMAUCHI Junji
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  National Research Institute for Child Health and Development
Elucidation of a molecular mechanism controlling myelination in normal and disease statesPrincipal Investigator
- Principal Investigator
  
  YAMAUCH Junji
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  National Research Institute for Child Health and Development
Studies on cellular signal transduction of PNS demyelinationPrincipal Investigator
- Principal Investigator
  
  YAMAUCHI Junji
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  National Research Institute for Child Health and Development
グリアー神経細胞相互作用によるミエリン形成の分子機構の解析Principal Investigator
- Principal Investigator
  
  山内淳司
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  National Research Institute for Child Health and Development
G蛋白質共役型受容体を介する細胞増殖抑制シグナルの解析Principal Investigator
- Principal Investigator
  
  山内淳司
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Nara Institute of Science and Technology

[Book] Gomperts・Kramer・Tathamシグナル伝達第2版翻訳2011
- Author(s)
  山内淳司
- Total Pages
  29
- Publisher
  メディカル・サイエンス・インターナショナル
- Data Source
  KAKENHI-PROJECT-23650200
[Book] 大豆たん白質研究2010
- Author(s)
  山内淳司
- Total Pages
  3
- Publisher
  デジタル総合印刷株式会社
- Data Source
  KAKENHI-PROJECT-22300123
[Journal Article] Rare Neurologic Disease-Associated Mutations of AIMP1 are Related with Inhibitory Neuronal Differentiation Which is Reversed by Ibuprofen2020
- Author(s)
  Yu Takeuchi, Marina Tanaka, Nanako Okura, Yasuyuki Fukui, Ko Noguchi, Yoshihiro Hayashi, Tomohiro Torii, Hiroaki Ooizumi, Katsuya Ohbuchi, Kazushige Mizoguchi, Yuki Miyamoto, and Junji Yamauchi
- Journal Title
  
  Medicines
  
  Volume: 7 Issue: 5 Pages: 25-25
- DOI
  10.3390/medicines7050025
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03564
[Journal Article] Expression of kinase-deficient MEK2 ameliorates Pelizaeus-Merzbacher disease phenotypes in mice2020
- Author(s)
  Yuki Miyamoto, Marina Tanaka, Hisanaka Ito, Hiroaki Ooizumi, Katsuya Ohbuchi, Kazushige Mizoguchi, Tomohiro Torii, and Junji Yamauchi
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 531, Issue: 4 Pages: 445-451
- DOI
  10.1016/j.bbrc.2020.07.131
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03564
[Journal Article] PP1C and PP2A are p70S6K phosphatases whose inhibition ameliorates HLD12-associated inhibition of oligodendroglial cell morphological differentiation2020
- Author(s)
  Naoto Matsumoto, Yuki Miyamoto, Kohei Hattori, Akihiro Ito, Hironori Harada, Hiroaki Oizumi, Katsuya Ohbuchi, Kazushige Mizoguchi, and Junji Yamauchi
- Journal Title
  
  Biomedicines
  
  Volume: 8 Issue: 4 Pages: 89-89
- DOI
  10.3390/biomedicines8040089
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03564
[Journal Article] Data on the effects of Charcot-Marie-Tooth disease type 2N-associated AARS missense mutation (Arg329-to-His) on the cell biological properties.2019
- Author(s)
  Imaizumi N, Takeuchi Y, Hirano H, Torii T, Seki Y, Morimoto T, Miyamoto Y, Sakagami H, Yamauchi J.
- Journal Title
  
  Data Brief
  
  Volume: 25 Pages: 104029-104029
- DOI
  10.1016/j.dib.2019.104029
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03564, KAKENHI-PROJECT-17K07127
[Journal Article] Defective neuronal and oligodendroglial differentiation by FTD3- and ALS17-associated Ile29-to-Val mutation of CHMP2B.2019
- Author(s)
  Yamawaki M, Akiba M, Matsumoto N, Watanabe N, Hattori K, Takeuchi Y, Morimoto T, Oizumi H, Ohbuchi K, Miyamoto Y, Yamauchi J.
- Journal Title
  
  Mol Genet Metab Rep.
  
  Volume: 19 Pages: 100458-100458
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03564
[Journal Article] Hypomyelinating leukodystrophy-associated mutation of RARS leads it to the lysosome, inhibiting oligodendroglial morphological differentiation.2019
- Author(s)
  Matsumoto N, Watanabe N, Iibe N, Tatsumi Y, Hattori K, Takeuchi Y, Oizumi H, Ohbuchi K, Torii T, Miyamoto Y, Yamauchi J.
- Journal Title
  
  Biochem Biophys Rep.
  
  Volume: 20 Pages: 100705-100705
- DOI
  10.1016/j.bbrep.2019.100705
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03564, KAKENHI-PROJECT-17K07127
[Journal Article] CMT type 2N disease-associated AARS mutant inhibits neurite growth that can be reversed by valproic acid2019
- Author(s)
  Tatsumi Yuriko、Matsumoto Naoto、Iibe Noriko、Watanabe Natsumi、Torii Tomohiro、Sango Kazunori、Homma Keiichi、Miyamoto Yuki、Sakagami Hiroyuki、Yamauchi Junji
- Journal Title
  
  Neuroscience Research
  
  Volume: 139 Pages: 69-78
- DOI
  10.1016/j.neures.2018.09.016
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04672, KAKENHI-PROJECT-17H03564, KAKENHI-PROJECT-17K07127, KAKENHI-PROJECT-16K07048
[Journal Article] BIG1/Arfgef1 and Arf1 regulate the initiation of myelination by Schwann cells in mice.2018
- Author(s)
  Miyamoto Y, Torii T, Tago K, Tanoue A, Takashima S, Yamauchi J
- Journal Title
  
  Sci Adv.
  
  Volume: 4 Issue: 4
- DOI
  10.1126/sciadv.aar4471
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07127, KAKENHI-PROJECT-17K07343, KAKENHI-PROJECT-17H03564
[Journal Article] Pull down assay for GTP-bound form of Sar1a reveals its activation during morphological differentiation.2018
- Author(s)
  Urai Y, Yamawaki M, Watanabe N, Seki Y, Morimoto T, Tago K, Homma K, Sakagami H, Miyamoto Y, Yamauchi J
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 503 Issue: 3 Pages: 2047-2053
- DOI
  10.1016/j.bbrc.2018.07.157
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K07127, KAKENHI-PROJECT-17K07343, KAKENHI-PROJECT-17H03564
[Journal Article] Treacher Collins syndrome 3 (TCS3)-associated POLR1C mutants are localized in the lysosome and inhibits chondrogenic differentiation.2018
- Author(s)
  Matsumoto N, Kaneko M, Watanabe N, Itaoka M, Seki Y, Morimoto T, Torii T, Miyamoto Y, Keiichi Homma, Yamauchi J
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 499 Issue: 1 Pages: 78-85
- DOI
  10.1016/j.bbrc.2018.03.136
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07127, KAKENHI-PROJECT-17H03564
[Journal Article] Effects of HLD-associated POLR1C mutant proteins on cellular localization and differentiation.2018
- Author(s)
  Hiraoka Y, Hattori K, Takeuchi Y, Yamawaki M, Watanabe N, Matsumoto N, Homma K, Miyamoto Y, Yamauchi J
- Journal Title
  
  Mol. Genet. Metab. Rep.
  
  Volume: 17 Pages: 80-82
- DOI
  10.1016/j.ymgmr.2018.11.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07127, KAKENHI-PROJECT-17H03564
[Journal Article] The promoter region of 46-kDa CNPase is sufficient for its expression in corpus callosum.2018
- Author(s)
  Miyamoto Y, Torii T, Tanoue A, Yamamoto M, Yamauchi J
- Journal Title
  
  Mol. Genet. Metab. Rep.
  
  Volume: 15 Pages: 78-79
- DOI
  10.1016/j.ymgmr.2018.03.003
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07127, KAKENHI-PROJECT-17H03564
[Journal Article] Neuregulin-1 type III knockout mice exhibit delayed migration of Schwann cell precursors.2017
- Author(s)
  Miyamoto Y, Torii T, Tanoue A, Kawahara K, Arai M, Tsumura H, Ogata T, Nagao M, Terada N, Yamamoto M, Takashima S, Yamauchi J
- Journal Title
  
  Biochemical and Biophysical Research Communication,
  
  Volume: 486 Issue: 2 Pages: 506-513
- DOI
  10.1016/j.bbrc.2017.03.074
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08463, KAKENHI-PROJECT-17K07127, KAKENHI-PROJECT-17H03564
[Journal Article] Data supporting the role of Fyn in embryonic sciatic nerve fasciculation.2017
- Author(s)
  Tomohiro Torii, Yuki Miyamoto, Kazuko Kawahara, Akito Tanoue, Yoichi Seki, Takako Morimoto, Masahiro Yamamoto, and Junji Yamauchi
- Journal Title
  
  Data Brief.
  
  Volume: 11 Pages: 358-363
- DOI
  10.1016/j.dib.2017.02.042
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07127, KAKENHI-PROJECT-17H03564
[Journal Article] Data on the effect of knockout of cytohesin-1 in myelination-related protein kinase signaling.2017
- Author(s)
  Ruri Tsuneishi, Naoto Matsumoto, Misa Itaoka, Yuki Urai, Minami Kaneko, Natsumi Watanabe, Shou Takashima, Yoichi Seki, Takako Morimoto, Hiroyuki Sakagami, Yuki Miyamoto, and Junji Yamauchi
- Journal Title
  
  Data Brief.
  
  Volume: 15 Pages: 234-239
- DOI
  10.1016/j.dib.2017.09.024
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07127, KAKENHI-PROJECT-15H04672, KAKENHI-PROJECT-17H03564
[Journal Article] Data on the effect of in vivo knockdown using artificial ErbB3 miRNA on Remak bundle structure.2017
- Author(s)
  Yuki Miyamoto, Tomohiro Torii, Kazuko Kawahara, Masashi Inoue, Takako Morimoto, Masahiro Yamamoto, and Junji Yamauchi
- Journal Title
  
  Data Brief.
  
  Volume: 12 Pages: 313-319
- DOI
  10.1016/j.dib.2017.04.014
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07127, KAKENHI-PROJECT-17H03564
[Journal Article] Data on the effect of hypomyelinating leukodystrophy 6 (HLD6)-associated mutations on the TUBB4A properties.2017
- Author(s)
  Yuki Miyamoto, Tomohiro Torii, Kazuko Kawahara, Nanami Hasegawa, Akito Tanoue, Yoichi Seki, Takako Morimoto, Megumi Funakoshi-Tago, Hiroomi Tamura, Keiichi Homma, Masahiro Yamamoto, and Junji Yamauchi
- Journal Title
  
  Data Brief.
  
  Volume: 11 Pages: 284-289
- DOI
  10.1016/j.dib.2017.02.024
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07127, KAKENHI-PROJECT-17H03564
[Journal Article] Arf6 guanine-nucleotide exchange factor cytohesin-2 regulates myelination in nerve2016
- Author(s)
  Tomohiro Torii, Nobuhiko Ohno, Yuki Miyamoto, Kazuko Kawahara, Yurika Saitoh, Kazuaki Nakamura, Shou Takashima, Hiroyuki Sakagami, Akito Tanoue, and Junji Yamauchi
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 460 Pages: 819-825
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25290028
[Journal Article] Yuki Miyamoto, Tomohiro Torii, Akito Tanoue, and Junji Yamauchi* (2016) VCAM1 acts in parallel with CD69 and is required for the initiation of oligodendrocyte myelination.2016
- Author(s)
  Yuki Miyamoto, Tomohiro Torii, Akito Tanoue, and Junji Yamauchi
- Journal Title
  
  Nat. Commun.
  
  Volume: 7 Pages: 13478-13478
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25290028
[Journal Article] Data supporting Arf6 regulation of Schwann cell differentiation and myelination2016
- Author(s)
  Tomohiro Torii, Yuki Miyamoto, Masahiro Yamamoto, Katsuya Ohbuchi, Hideki Tsumura, Kazuko Kawahara, Akito Tanoue, Hiroyuki Sakagami, and Junji Yamauchi
- Journal Title
  
  Data Brief
  
  Volume: 5 Pages: 388-395
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25290028
[Journal Article] Arf6 mediates Schwann cell differentiation and myelination.2015
- Author(s)
  Tomohiro Torii, Yuki Miyamoto, Masahiro Yamamoto, Katsuya Ohbuchi, Hideki Tsumura, Kazuo Kawahara, Akito Tanoue, Hiroyuki Sakagami, and Jyunji Yamauchi
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 465 Issue: 3 Pages: 450-457
- DOI
  10.1016/j.bbrc.2015.08.038
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26830054, KAKENHI-PROJECT-221S0003, KAKENHI-PUBLICLY-26117523, KAKENHI-PROJECT-15H04672, KAKENHI-PROJECT-25290028
[Journal Article] Arf6 guanine-nucleotide exchange factor cytohesin-2 regulates myelination in nerves.2015
- Author(s)
  Torii T, Ohno N, Miyamoto Y, Kawahara K, Saitoh Y, Nakamura K, Takashima S, Sakagami H, Tanoue A, Yamauchi J
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 460 Pages: 819-825
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-26117523
[Journal Article] Data supporting Arf6 regulation of Schwann cell differentiation and myelination2015
- Author(s)
  Torii T, Miyamoto Y, Yamamoto M, Ohbuchi K, Tsumura H, Kawahara K, Tanoue A, Sakagami H, Yamauchi J
- Journal Title
  
  Data Brief
  
  Volume: 5 Pages: 388-395
- DOI
  10.1016/j.dib.2015.09.025
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-26117523
[Journal Article] Involvement of the Tyro3 receptor and its intracellular partner Fyn signaling in Schwann cell myelination.2015
- Author(s)
  Yuki Miyamoto, Tomohiro Torii, Shuji Takada, Nobuhiko Ohno, Yurika Saitoh, Kazuaki Nakamura, Akihito Ito, Toru Ogata, Nobuo Terada, Akito Tanoue, and Junji Yamauchi
- Journal Title
  
  Mol. Biol. Cell
  
  Volume: 26 Issue: 19 Pages: 3489-3503
- DOI
  10.1091/mbc.e14-05-1020
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26830054, KAKENHI-PUBLICLY-26117523, KAKENHI-PROJECT-25460267, KAKENHI-PROJECT-25290028, KAKENHI-PROJECT-26282159
[Journal Article] Hypomyelinating leukodystrophy-associated missence mutation in HSPD1 blunts mitochondrial dynamics.2015
- Author(s)
  Yuki Miyamoto, Takahiro Eguchi, Kazuo Kawahara, Nanami Hasegawa, Kazuaki Nakamura, Megumi Funakoshi-Tago, Akito Tanoue, Hiroomi Tamura, and Junji Yamauchi
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 462 Issue: 3 Pages: 275-281
- DOI
  10.1016/j.bbrc.2015.04.132
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26830054, KAKENHI-PUBLICLY-26117523, KAKENHI-PROJECT-25460073, KAKENHI-PROJECT-25290028
[Journal Article] Arf6 guanine-nucleotide exchange factor cytohesin-2 binds to CCDC120 and is transported along neurites to mediate neurite growth.2014
- Author(s)
  Tomohiro Torii*, Yuki Miyamoto, Kenji Tago, Kazunori Sango, Kazuaki Nakamura, Atsushi Sanbe, Akito Tanoue, and Junji Yamauchi
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 289 Pages: 33887-33903
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-26117523
[Journal Article] Rab35, acting through ACAP2 switching off Arf6, negatively regulates oligodendrocyte differentiation and myelination2014
- Author(s)
  Miyamoto Y, Yamamori N, Torii T, Tanoue A, Yamauchi J
- Journal Title
  
  Mol. Biol. Cell
  
  Volume: 25 Issue: 9 Pages: 1532-1542
- DOI
  10.1091/mbc.e13-10-0600
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25290028, KAKENHI-PUBLICLY-26117523, KAKENHI-PROJECT-26830054
[Journal Article] Hypomyelinating leukodystrophy-associated missense mutant of FAM126A/hyccin/DRCTNNB1A aggregates in the endoplasmic reticulum.2014
- Author(s)
  Yuki Miyamoto, Takahiro Eguchi, Tomohiro Torii, Kazuaki Nakamura, Akito Tanoue, and Junji Yamauchi
- Journal Title
  
  J. Clin. Neurosci.
  
  Volume: 21 Issue: 6 Pages: 1033-1039
- DOI
  10.1016/j.jocn.2013.09.014
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-26117523, KAKENHI-PROJECT-26830054
[Journal Article] In vivo knockdown of ErbB3 in mice inhibits Schwann cell precursor migration.2014
- Author(s)
  Tomohiro Torii, Yuki Miyamoto, Shuji Takada, Hideki Tsumura, Miyuki Arai, Kazuaki Nakamura, Katsuya Ohbuchi, Masahiro Yamamoto, Akito Tanoue, and Junji Yamauchi
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 452 Issue: 3 Pages: 782-788
- DOI
  10.1016/j.bbrc.2014.08.156
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-26117523, KAKENHI-PROJECT-26830054
[Journal Article] Arf6 guanine nucleotide exchange factor cytohesin-2 binds to CCDC120 and is transported along neurites to mediate neurite growth2014
- Author(s)
  Torii T, Miyamoto Y, Tago K, Sango K, Nakamura K, Sanbe A, Tanoue A, Yamauchi J
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 289 Pages: 33887-33903
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25290028
[Journal Article] ignaling through Arf6 guanine-nucleotide exchange factor cytohesin-1 regulates migration in Schwann cells2013
- Author(s)
  Yuki Miyamoto, Tomohiro Torii, Kazuaki Nakamura, Shou Takashima, Atsushi Sanbe, Akito Tanoue, and Junji Yamauchi
- Journal Title
  
  Cellular Signaling
  
  Volume: 25 Issue: 6 Pages: 1379-1387
- DOI
  10.1016/j.cellsig.2013.03.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650200
[Journal Article] Akt and PP2A reciprocally regulate the guanine nucleotide exchange factor Dock6 to control axon growth of sensory neurons.2013
- Author(s)
  Yuki Miyamoto, Tomohiro Torii, Natsuki Yamamori, Toru Ogata, and Akito Tanoue, and Junji Yamauchi
- Journal Title
  
  Science Signaling (Science sister journal)
  
  Volume: 6 Issue: 265
- DOI
  10.1126/scisignal.2003661
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650200, KAKENHI-PROJECT-25290028
[Journal Article] n vivo expression of the Arf6 guanine-nucleotide exchange factor cytohesin-1 in mice exhibits enhanced myelin thickness in nerves.2013
- Author(s)
  Tomohiro Torii, Yuki Miyamoto, Naoko Onami, Hideki Tsumura, Noriko Nemoto, Katsumasa Kawahara, Minoru Kato, Jun Kotera, Kazuaki Nakamura, Akito Tanoue, and Junji Yamauchi
- Journal Title
  
  Journal of Molecular Neuroscience
  
  Volume: 51 Issue: 2 Pages: 522-531
- DOI
  10.1007/s12031-013-0018-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650200
[Journal Article] Phosphorylation of cytohesin-1 by Fyn is required for initiation of myelination and the extent of myelination during development2012
- Author(s)
  Junji Yamauchi, Yuki Miyamoto, Tomohiro Torii, Shou Takashima, Kazumi Kondo, Katsumasa Kawahara, Noriko Nemoto, Jonah R. Chan, Gozoh Tsujimoto, and Akito Tanoue
- Journal Title
  
  Sci. Signal
  
  Volume: 5 Issue: 243
- DOI
  10.1126/scisignal.2002802
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300123, KAKENHI-PROJECT-23591224, KAKENHI-PROJECT-23650200
[Journal Article] Dock7 negatively regulates myelination2011
- Author(s)
  Junji Yamauchi, Yuki Miyamoto, et. al.
- Journal Title
  
  J. Neurosci.
  
  Volume: J. Neurosci. Pages: 12579-12592
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650200
[Journal Article] The atypical guanine-nucleotide exchange factor, Dock7, negatively regulates Schwann cell differentiation and myelination.2011
- Author(s)
  Junji Yamauchi, Yuki Miyamoto, Hajime Hamasaki, Atsushi Sanbe, Shinji Kusakawa, Akane Nakamura, Hideki Tsumura, Masahiro Maeda, Noriko Nemoto, Katsumasa Kawahara, Tomohiro Torii, and Akito Tanoue
- Journal Title
  
  J. Neurosci
  
  Volume: 31 Issue: 35 Pages: 12579-12592
- DOI
  10.1523/jneurosci.2738-11.2011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300123, KAKENHI-PROJECT-23650200, KAKENHI-PROJECT-23791209
[Journal Article] The atypical guanine-nucleotide exchange factor, Dock7, negatively regulates Schwann cell differentiation and myelination2011
- Author(s)
  山内淳司, ら
- Journal Title
  
  J.Neurosci.
  
  Volume: 31 Pages: 12579-12592
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300123
[Journal Article] Fluoxetine promotes gliogenesis during neural differentiation in mouse ES cells.2010
- Author(s)
  Shinji Kusakawa, Kazuaki Nakamura, Yuki Miyamoto, Atsushi Sanbe, Tomohiro Torii, Junji Yamauchi, Akito Tanoue
- Journal Title
  
  J.Neurosci.Res.
  
  Volume: 88 Pages: 3479-3487
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300123
[Journal Article] The mood stabilizer valproic acid improves defective neurite formation caused by Charcot-Marie-Tooth disease-associated mutant Rab7 through the JNK signaling pathway.2010
- Author(s)
  Junji Yamauchi, Tomohiro Torii, Shinji Kusakawa, Atsushi Sanbe, Kazuaki Nakamura, Shou Takashima, Hajime Hamasaki, Shogo Kawaguchi, Yuki Miyamoto, Akito Tanoue
- Journal Title
  
  J.Neurosci.Res.
  
  Volume: 88 Pages: 3189-3197
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300123
[Journal Article] Cellular signaling of Dock family proteins in neural functions.2010
- Author(s)
  Yuki Miyamoto, Junji Yamauchi
- Journal Title
  
  Cell.Signal.
  
  Volume: 22 Pages: 175-182
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300123
[Journal Article] Valproic acid-inducible Arl4D and cytohesin-2/ARNO, acting through the downstream Arf6, regulate neurite outgrowth in N1E-115 cells2009
- Author(s)
  Junji Yamauchi, Yuki Miyamoto, Tomohiro Torii, Reiko Mizutani, Kazuaki Nakamura, Atsushi Sanbe, Hiroshi Koide, Shinji Kusakawa, Akito Tanoue
- Journal Title
  
  Exp.Cell Res. 315
  
  Pages: 2043-2052
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500340
[Journal Article] Valproic acid-inducible Arl4D and cytohesin-2/ARNO, acting through the downstream Arf6, regulate neurite outgrowth in N1E-115 cells.2009
- Author(s)
  Junji Yamauchi, Yuki Miyamoto, Tomohiro Torii, Reiko Mizutani, Kazuaki Nakamura, Atsushi Sanbe, Hiroshi Koide, Shinji Kusakawa, Akito Tanoue
- Journal Title
  
  Exp. Cell Res 315巻
  
  Pages: 2043-2052
- Data Source
  KAKENHI-PROJECT-19500340
[Journal Article] ErbB2 directly activates the exchange factor Dock7 to promote Schwann cell migration.2008
- Author(s)
  Junji Yamauchi, Yuki Miyamoto, Jonah R. Chan, Akito Tanoue
- Journal Title
  
  J. Cell Biol. 181巻
  
  Pages: 351-365
- Data Source
  KAKENHI-PROJECT-19500340
[Journal Article] ErbB2 directly activates the exchange factor Dock7 to promote Schwann cell migration2008
- Author(s)
  Junji Yamauchi, Yuki Miyamoto, Jonah R. Chan, Akito Tanoue
- Journal Title
  
  J. Cell Biol. 181
  
  Pages: 351-365
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500340
[Journal Article] Neurofibromatosis 2 tumor suppressor, the gene induced by valproic acid, mediates neurite outgrowth through interaction with paxillin2008
- Author(s)
  Junji Yamauchi, Yuki Miyamoto, Shinji Kusakawa, Tomohiro Torii, Reiko Mizutani, Atsushi Sanbe, Hideki Nakajima, Nobutaka Kiyokawa, Akito Tanoue
- Journal Title
  
  Exp. Cell Res. 314
  
  Pages: 2279-2288
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500340
[Journal Article] Cdk5 phosphorylation of WAVE2 regulates oligodendrocyte precursor cell migration through nonreceptor tyrosine kinase Fyn.2008
- Author(s)
  Yuki Miyamoto, Junji Yamauchi, Akito Tanoue
- Journal Title
  
  J. Neurosci 28
  
  Pages: 8326-8337
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500340
[Journal Article] Cdk5 phosphorylation of WAVE2 regulates oligodendrocyte precursor cell migration through nonreceptor tyrosine kinase Fyn.2008
- Author(s)
  Yuki Miyamoto, Junji Yamauchi, Akito Tanoue
- Journal Title
  
  J. Neurosci 28巻
  
  Pages: 8326-8337
- Data Source
  KAKENHI-PROJECT-19500340
[Journal Article] Gadd45a,the gene induced by the mood stabilizer valproic acid,regulates neurite outgrowth through JNK and the substrate paxillin in N1E-115 neuroblastoma cells2007
- Author(s)
  Junji Yamauchi, Yuki Miyamoto, Mayu Murabe, Yoko Fujiwara, Atsushi Sanbe, Yoko Fujita, Shoko Murase, and Akito Tanoue
- Journal Title
  
  Exp.Cell Res. 313
  
  Pages: 1886-1887
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500340
[Journal Article] Gadd45a, the gene induced by the mood stabilizer valproic acid, regulates neurite outgrowth through JNK and the substrate paxillin in N1E-115 neuroblastoma cells.2007
- Author(s)
  Junji Yamauchi, Yuki Miyamoto, Mayu Murabe, Yoko Fujiwara, Atsushi Sanbe, Yoko Fujita, Shoko Murase, Akito Tanoue
- Journal Title
  
  Exp. Cell Res 313巻
  
  Pages: 1886-1897
- Data Source
  KAKENHI-PROJECT-19500340
[Journal Article] Dock6, a Dock-C subfamily guanine-nucleotide exchanger, has the dual specificity for Rac1 and Cdc42 and regulates neurite outgrowth2007
- Author(s)
  Yuki Miyamoto, Junji Yamauchi, Atsushi Sanbe, Akito Tanoue
- Journal Title
  
  Exp. Cell Res. 313巻4号
  
  Pages: 791-804
- Data Source
  KAKENHI-PROJECT-17700350
[Journal Article] Cyclin-dependent kinase 5 regulates the differentiation of oligodendrocyte precursor cells through the direct phosphorylation of paxillin.2007
- Author(s)
  Yuki Miyamoto, Junji Yamauchi, Jonah R. Chan, Atsumasa Okada, Yasuhiro Tomooka, Shin-ichi Hisanaga, Akito Tanoue
- Journal Title
  
  J. Cell Sci 120巻
  
  Pages: 4355-4366
- Data Source
  KAKENHI-PROJECT-19500340
[Journal Article] Cyclin-dependent kinase 5 regulates the differentiation of oligodendrocyte precursor cells through the direct phosphorylation of paxillin2007
- Author(s)
  Yuki Miyamoto, Junji Yamauchi, Jonah R.Chan, Atsumasa Okada, Yasuhiro Tomooka, Shin-ichi Hisanaga, and Akito Tanoue
- Journal Title
  
  J.Cell Sci 120
  
  Pages: 4355-4366
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500340
[Journal Article] The polarity protein Par-3 directly interacts with the p75 neurotrophin receptor to regulate myelination2006
- Author(s)
  Jonah R.Chan, Christine Jolicoeur, Junji Yamauchi, Jimmy Elliott, James P.Fawcett, Benjamin K.Ng, Michael Cayouette
- Journal Title
  
  Science 314巻3号
  
  Pages: 832-836
- Data Source
  KAKENHI-PROJECT-17700350
[Journal Article] TrkB binds and tyrosine-phosphorylates Tiam1 leading to activation of Rac1 and induction of changes in cellular morphology2006
- Author(s)
  Yuki Miyamoto, Junji Yamauchi, Akito Tanoue, Chengbiao Wu, William C. Mobley
- Journal Title
  
  Proc. Natl. Acad. Sci. USA 103巻27号
  
  Pages: 10444-10449
- Data Source
  KAKENHI-PROJECT-17700350
[Journal Article] A novel embryotoxic estimation method of valproic acid using ES cell differentiation system2006
- Author(s)
  Mayu Murabe, Junji Yamauchi, Yoko Fujiwara, Masami Hiroyama, Sanbe Atsushi, Akito Tanoue
- Journal Title
  
  Biochem. Biophys. Res. Commun. 532巻1号
  
  Pages: 164-169
- Data Source
  KAKENHI-PROJECT-17700350
[Journal Article] JNK phosphorylation of paxillin, acting through the Rac1 and Cdc42 signaling cascade, mediates neurite extension in N1E-115 cells2006
- Author(s)
  Junji Yamauchi, Yuki Miyamoto, Atsushi Sanbe, Akito Tanoue
- Journal Title
  
  Exp. Cell Res. 312巻15号
  
  Pages: 2954-2961
- Data Source
  KAKENHI-PROJECT-17700350
[Journal Article] Ras activation of a Rac1 exchange factor, Tiam1, mediates neurotrophin-3-induced Schwann cell migration.2005
- Author(s)
  山内淳司
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 102巻41号
  
  Pages: 14889-14894
- Data Source
  KAKENHI-PROJECT-17700350
[Journal Article] The neurotrophin-3 receptor TrkC directly phosphorylates and activates the nucleotide exchange factor Dbs to enhance Schwann cell migration.2005
- Author(s)
  山内淳司
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 102巻14号
  
  Pages: 5198-5203
- Data Source
  KAKENHI-PROJECT-17700350
[Journal Article] The embryotoxic test of CBZ using ES cell differentiation test
- Author(s)
  Mayu Murabe, Junji Yamauchi, Yoko Fujiwara, Yuki Miyamoto, Masami Hiroyama, Sanbe Atsushi, Akito Tanoue
- Journal Title
  
  Biochem. Biophys. Res. Commun. (印刷中)
- Data Source
  KAKENHI-PROJECT-17700350
[Journal Article] Neurofibromatosis 2 tumor suppressor, the gene induced by valproic acid, mediates neurite outgrowth through interaction with paxillin.
- Author(s)
  Junji Yamauchi, Yuki Miyamoto, Shinji Kusakawa, Tomohiro Torii, Reiko Mizutani, Atsushi Sanbe, Hideki Nakajima, Nobutaka Kiyokawa, Akito Tanoue
- Journal Title
  
  Exp. Cell Res 314巻
  
  Pages: 2279-2288
- Data Source
  KAKENHI-PROJECT-19500340
[Patent] ペリチェウス・メルツバッハ病治療方法及びそれに用いる治療剤2012
- Inventor(s)
  山内淳司、田上昭人、宮本幸、鳥居知宏、前田雅弘
- Industrial Property Rights Holder
  山内淳司、田上昭人、宮本幸、鳥居知宏、前田雅弘
- Filing Date
  2012-02-03
- Data Source
  KAKENHI-PROJECT-22300123
[Patent] 中枢神経髄鞘形成不全の治療用組成物及び治療剤2010
- Inventor(s)
  山内淳司、田上昭人、宮本幸、鳥居知宏、友岡康弘
- Industrial Property Rights Holder
  山内淳司、田上昭人、宮本幸、鳥居知宏、友岡康弘
- Filing Date
  2010-12-17
- Data Source
  KAKENHI-PROJECT-22300123
[Patent] 末梢神経軸索の再生剤及び再生方法2010
- Inventor(s)
  山内淳司
- Industrial Property Rights Holder
  (独)国立成育医療研究センター
- Industrial Property Number
  2010-209899
- Filing Date
  2010-10-04
- Data Source
  KAKENHI-PROJECT-22300123
[Patent] 末梢神経軸索の再生剤及び再生方法2010
- Inventor(s)
  山内淳司、田上昭人、宮本幸、鳥居知宏
- Industrial Property Rights Holder
  山内淳司、田上昭人、宮本幸、鳥居知宏
- Filing Date
  2010-10-04
- Overseas
- Data Source
  KAKENHI-PROJECT-22300123
[Patent] 中枢神経髄鞘形成不全の治療用組成物及び治療剤2010
- Inventor(s)
  山内淳司
- Industrial Property Rights Holder
  (独)国立成育医療研究センター
- Industrial Property Number
  2010-281777
- Filing Date
  2010-12-17
- Data Source
  KAKENHI-PROJECT-22300123
[Patent] 中枢神経髄鞘形成不全の治療用組成物および中枢神経髄鞘形成促進方法2008
- Inventor(s)
  山内淳司, 田上昭人, 宮本幸, 鳥居知宏
- Industrial Property Rights Holder
  山内淳司,田上昭人,宮本幸,鳥居知宏
- Industrial Property Number
  2008-208155
- Filing Date
  2008-08-12
- Data Source
  KAKENHI-PROJECT-19500340
[Presentation] Intercellular molecules whose primary role is in the immune system can also play an unexpected role in the CNS2018
- Author(s)
  宮本　幸、山内淳司
- Organizer
  日本神経科学会（シンポジウム）
- Data Source
  KAKENHI-PROJECT-17H03564
[Presentation] VCAM1 regulates oligodendrocyte myelination2017
- Author(s)
  宮本　幸、山内淳司
- Organizer
  日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-17H03564
[Presentation] α4β1インテグリンリガンドとVCAM1受容体による中枢神経系のミエリン形成機構2017
- Author(s)
  宮本　幸、山内淳司
- Organizer
  生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-17H03564
[Presentation] ErbB3 is required for Schwann cell precursor migration2015
- Author(s)
  宮本　幸、山内淳司
- Organizer
  日本神経科学会大会（ミニシンポジウム）
- Place of Presentation
  神戸
- Year and Date
  2015-07-01
- Data Source
  KAKENHI-PROJECT-25290028
[Presentation] Disease-associated modification of hereditary demyelinating disorder-related protein dynamics2015
- Author(s)
  宮本　幸、山内淳司
- Organizer
  日本神経化学会大会（シンポジウム）
- Place of Presentation
  大宮
- Year and Date
  2015-09-01
- Data Source
  KAKENHI-PROJECT-25290028
[Presentation] Tyro3受容体とFynキナーゼは、ミエリン形成を司る新しいシグナル複合体を形成する2015
- Author(s)
  宮本　幸、山内淳司
- Organizer
  日本分子生物学会・日本生化学会合同年会（ワークショップ）
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25290028
[Presentation] Derivation of oligodendrocytes from human iPS cells and monkey ES cells maintained in a single-cell and feeder-free culture2015
- Author(s)
  山下智子、土井綾乃、小林桜子、小野貴史、鈴木　豊、荒木利博、青木久範、佐藤直也、宮本　幸、山内淳司、板東良雄、吉田成孝
- Organizer
  日本神経科学会大会（ミニシンポジウム）
- Place of Presentation
  神戸
- Year and Date
  2015-07-01
- Data Source
  KAKENHI-PROJECT-25290028
[Presentation] FynキナーゼとArf6交換因子cytohesin-1による新規のミエリン形成メカニズム2013
- Author(s)
  山内淳司
- Organizer
  日本生化学会（シンポジウム）
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25290028
[Presentation] 低分子量 GTP 結合蛋白質による新規のミエリン形成メカニズム (シンポジウム)2013
- Author(s)
  宮本幸, 山内淳司
- Organizer
  日本解剖学会大会
- Place of Presentation
  香川
- Data Source
  KAKENHI-PROJECT-23650200
[Presentation] Dock6 交換因子のAkt のリン酸化状態によって制御される軸索伸長の新規メカニズム(シンポジウム)2013
- Author(s)
  宮本幸, 山内淳司
- Organizer
  日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23650200
[Presentation] Fyn キナーゼと Arf6 交換因子cytohesin-1 による新規のミエリン形成メカニズム(シンポジウム)2013
- Author(s)
  山内淳司
- Organizer
  日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23650200
[Presentation] Dock6交換因子のAktのリン酸化状態によって制御される軸索伸長の新規メカニズム2013
- Author(s)
  宮本　幸、山内淳司
- Organizer
  日本生化学会（シンポジウム）
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23650200
[Presentation] Novel signal transduction pathway controlling myelination(シンポジウム New dynamic signaling to form unique structures between glial and neuronal cells)2012
- Author(s)
  宮本幸、山内淳司
- Organizer
  日本神経科学会大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22300123
[Presentation] Novel signal transduction pathway controlling myelination(シンポジウム)2012
- Author(s)
  宮本幸, 山内淳司
- Organizer
  日本神経科学会大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23650200
[Presentation] Novel signal transduction pathway controlling myelination2012
- Author(s)
  宮本　幸、山内淳司
- Organizer
  日本神経科学会大会（シンポジウム）
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22300123
[Presentation] ダイナミックな形態分化を伴い, 神経軸索のミエリン化を制御するマウスRho 活性化因子 Dock7(シンポジウム)2012
- Author(s)
  山内淳司
- Organizer
  日本生化学会大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23650200
[Presentation] Novel signal transduction pathway controlling myelination2012
- Author(s)
  宮本　幸、山内淳司
- Organizer
  日本神経科学会大会（シンポジウム）
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23650200
[Presentation] ダイナミックな形態分化を伴い、神経軸索のミエリン化を制御するマウスRho活性化因子Dock72011
- Author(s)
  山内淳司
- Organizer
  日本生化学会大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22300123
[Presentation] ダイナミックな形態分化を伴い、神経軸索のミエリン化を制御するマウスRho活性化因子Dock72011
- Author(s)
  山内淳司
- Organizer
  日本生化学会大会(招待講演)
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23650200
[Presentation] ダイナミックな形態分化を伴い、神経軸索のミエリン化を制御するマウスRho活性化因子Dock7(シンポジウム細胞の形態・運動を制御するシグナル伝達ネットワーク)2011
- Author(s)
  山内淳司
- Organizer
  日本生化学会大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22300123
[Presentation] Fluoxetine promotes gliogenesis during neural differentiation in mouse ES cells2010
- Author(s)
  草川森士、宮本幸、三部篤、中村和昭、鳥居知宏、田上昭人、阿久津英憲、梅澤明弘、山内淳司
- Organizer
  日本神経科学会・日本神経化学会・日本神経回路学会合同年会
- Place of Presentation
  神戸
- Year and Date
  2010-09-03
- Data Source
  KAKENHI-PROJECT-22300123
[Presentation] Control of myelination by oligodendrocytes through the novel phosphorylation mechanism of cytoskeletal proteins(シンポジウム企画/座長山内淳司、加藤裕教)2009
- Author(s)
  宮本幸、田上昭人、久永真市、山内淳司
- Organizer
  日本神経科学会大会
- Place of Presentation
  名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-19500340
[Presentation] 末梢神経ミエリン形成を司どるシグナル伝達(2008年度日本生化学会奨励賞)2008
- Author(s)
  山内淳司
- Organizer
  日本生化学会・日本分子生物学会合同年会
- Place of Presentation
  神戸国際展示場
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-19500340
[Presentation] 末梢神経ミエリン形成を司どるシグナル伝達2008
- Author(s)
  山内淳司
- Organizer
  日本生化学会・日本分子生物学会合同年会
- Place of Presentation
  神戸国際展示場
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-19500340

1. KATOH Hironori (50303847)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. KAWAHARA KAZUKO

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
3. TERADA Nobuo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 宮本幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 12 results
5. 阪上洋行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

YAMAUCHI Junji 山内 淳司

山内 淳司 ヤマウチ ジユンジ

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Signaling mechanism for myelin maintenancePrincipal Investigator

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脱ミエリン病で特異的に活性化される分子経路を抑制することで、病態を改善する試みPrincipal Investigator

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Negative regulation of axonal myelinationPrincipal Investigator

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A search of novel molecular mechanisms regulating neural progenitor cell proliferation in the cerebral cortex

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Evaluation of a drug-target-molecule for demyelinating disorders using Dock7 knockdown mousePrincipal Investigator

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Elucidation of a molecular mechanism controlling myelination in normal and disease statesPrincipal Investigator

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Studies on cellular signal transduction of PNS demyelinationPrincipal Investigator

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グリアー神経細胞相互作用によるミエリン形成の分子機構の解析Principal Investigator

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G蛋白質共役型受容体を介する細胞増殖抑制シグナルの解析Principal Investigator

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[Book] Gomperts・Kramer・Tathamシグナル伝達第2版翻訳2011

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[Book] 大豆たん白質研究2010

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[Journal Article] Rare Neurologic Disease-Associated Mutations of AIMP1 are Related with Inhibitory Neuronal Differentiation Which is Reversed by Ibuprofen2020

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[Journal Article] Expression of kinase-deficient MEK2 ameliorates Pelizaeus-Merzbacher disease phenotypes in mice2020

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[Journal Article] PP1C and PP2A are p70S6K phosphatases whose inhibition ameliorates HLD12-associated inhibition of oligodendroglial cell morphological differentiation2020

YAMAUCHI Junji 山内淳司

山内淳司ヤマウチジユンジ