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Imagawa Tomoyuki  今川 智之

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IMAGAWA Tomoyuki  今川 智之

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Researcher Number 20336548
Other IDs
Affiliation (Current) 2025: 地方独立行政法人神奈川県立病院機構神奈川県立こども医療センター(臨床研究所), 臨床研究所, 部長
Affiliation (based on the past Project Information) *help 2013: 横浜市立大学, 附属病院, 准教授
2007 – 2009: 横浜市立大学, 附属病院, 准教授
2006: Yokohama City University, Medical Hospital, Associate professor, 付属病院, 準教授
2006: 横浜市立大学, 附属病院, 準教授
2005: 横浜市立大学, 大学病院, 助手
2005: 横浜市立大学, 附属病院, 助手
2002 – 2004: 横浜市立大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Pediatrics
Except Principal Investigator
Pediatrics / Pediatrics
Keywords
Principal Investigator
マイクロアレイ / RNA / 蛋白解析 / 急性期・回復期変動解析 / 川崎病 / 質量分析 / 二次元電気泳動 / 小児 / プロテオミクス / 自己抗体 / 2次元電気泳動 / 小児リウマチ性疾患 … More
Except Principal Investigator
… More IL-6 / CpG motif / 原因検索 / DNAチップ / プロテオーム解析法 / 抗IL-6レセプター抗体 / hypercytokine diseases / investigation for pathogenesis / anti IL-6 receptor antibody / juvenile idiopathic arthritis / 若年性特発性関節炎 / 高サイトカイン病 / 若年性突発性関節炎 / cytokines / influenza virus / nasal mucosa vaccine / ワクチン / 経鼻投与 / インフルエンザウイルス / CpGモチーフ / インフルエンザ / サイトカイン / インフルエンザ・ウイルス / 経鼻粘膜ワクチン / 小児免疫・アレルギー・膠原病学 / 小児免疫学 / Nod蛋白 / TLR蛋白 / cytokine storm / サイトカインストーム / 免疫疾患 / 乳幼児 / 自然免疫 / 炎症性サイトカイン / 軟骨細胞 / 成長板 / Th2バランス / Th1 / ケモカイン / 治療前後 / プロテオーム / 病因蛋白質 / 川崎病 Less
  • Research Projects

    (8 results)
  • Research Products

    (31 results)
  • Co-Researchers

    (9 People)
  •  Analysis and therapeutic research for growth impairment accompanied with chronic inflammatory syndrome of children as dysregulation of proinflammatory cytokines

    • Principal Investigator
      YOKOTA Shumpei
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Yokohama City University
  •  TLR/Nod proteins in infants from dysregulation Pathological analysis Cytokine Storm

    • Principal Investigator
      YOKOTA Shumpei
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pediatrics
    • Research Institution
      Yokohama City University
  •  The effect of inflammatory cytokines on the differentiation of chondrogenic progenitor cells in the growth plates

    • Principal Investigator
      MORI Masaaki
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Yokohama City University
  •  プロテオーム解析法を用いた川崎病患者における病因蛋白質の網羅的解析

    • Principal Investigator
      YOKOTA Shumpei
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Pediatrics
    • Research Institution
      Yokohama City University
  •  川崎病急性期と回復期における末梢血細胞中のmRNA発現変動を用いた病因病態解析Principal Investigator

    • Principal Investigator
      今川 智之
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pediatrics
    • Research Institution
      Yokohama City University
  •  Exhaustive analysis about juvenile idiopathic arthritis by using an anti-IL-6 receptor antibody

    • Principal Investigator
      YOKOTA Shumpei
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pediatrics
    • Research Institution
      Yokohama City University
  •  小児膠原病患者における自己抗体対応抗原タンパク質の網羅的解析Principal Investigator

    • Principal Investigator
      今川 智之
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pediatrics
    • Research Institution
      Yokohama City University
  •  Development and clinical application of nasal mucosa vaccine in influenza virus

    • Principal Investigator
      MORI Masaaki
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Yokohama City University

All 2013 2012 2011 2009 2008 2006 2005 Other

All Journal Article Presentation

  • [Journal Article] Radiologic analysis of the effect of tocilizumab on hands and large joints in children with systemic juvenile idiopathic arthritis2013

    • Author(s)
      Inaba Y, Ozawa R, Aoki C, Imagawa T, Mori M, Hara R, Miyamae T, Saito T, Yokota S.
    • Journal Title

      Mod Rheumatol

      Volume: 23(4) Issue: 4 Pages: 667-73

    • DOI

      10.1007/s10165-012-0711-0

    • NAID

      10031189160

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591546
  • [Journal Article] Efficacy, pharmacokinetics, and safety of adalimumab in pediatric patients with juvenile idiopathic arthritis in Japan2012

    • Author(s)
      .Imagawa T, Takei S, Umebayashi H, Yamaguchi K, Itoh Y, Kawai T, Iwata N, Murata T, Okafuji I, Miyoshi M, Onoe Y, Kawano Y, Kinjo N, Mori M, Mozaffarian N, Yokota S, et al
    • Journal Title

      Clin Rheumatol.

      Volume: -

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591546
  • [Journal Article] Definitive differences in laboratory and radiological characteristics between two subtypes of juvenile idiopathic arthritis: systemic arthritis and polyarthritis2012

    • Author(s)
      Ozawa R, Inaba Y, Mori M, Hara R, Kikuchi M, Higuchi R, Miyamae T, Imagawa T, Fujiwara T, Saito T, Yokota S
    • Journal Title

      Mod Rheumatol

      Volume: 22 Pages: 558-64

    • NAID

      10031027084

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591546
  • [Journal Article] Definitive differences in laboratory and radiological characteristics between two subtypes of juvenile idiopathic arthritis : systemic arthritis and polyarthritis2012

    • Author(s)
      Ozawa R, Inaba Y, Mori M, Hara R, Kikuchi M, Higuchi R, Miyamae T, Imagawa T, Fujiwara T, Saito T, Yokota S.
    • Journal Title

      Mod Rheumatol

      Volume: 22(4) Issue: 4 Pages: 558-64

    • DOI

      10.1007/s10165-011-0540-6

    • NAID

      10031027084

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591546
  • [Journal Article] Efficacy, pharmacokinetics, and safety of adalimumab in pediatric patients with juvenile idiopathic arthritis in Japan.2012

    • Author(s)
      Imagawa T, Takei S, ---, Kawai S, Yokota S
    • Journal Title

      Clin Rheumatol.

      Volume: 31 Issue: 12 Pages: 1713-1721

    • DOI

      10.1007/s10067-012-2082-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591449, KAKENHI-PROJECT-23591546
  • [Journal Article] Guidance on the use of adalimumab for juvenile idiopathic arthritis in Japan2012

    • Author(s)
      Yokota S, Imagawa T, Murata T, Tomiita M, Itoh Y, Fujikawa S, Takei S, Mori M
    • Journal Title

      Mod Rheumatol.

      Volume: 22 Pages: 491-7

    • NAID

      10031026845

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591546
  • [Journal Article] Safety and efficacy of long-term etanercept in the treatment of methotrexate-refractory polyarticular-course juvenile idiopathic arthritis in Japan.2012

    • Author(s)
      .Mori M, Takei S, Imagawa T, Imanaka H, Nerome Y, Higuchi R, Kawano Y, Yokota S, et al
    • Journal Title

      Mod Rheumatol

      Volume: 22 Issue: 5 Pages: 720-6

    • DOI

      10.1007/s10165-011-0578-5

    • NAID

      10031027821

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591546
  • [Journal Article] Guidance on the use of adalimumab for juvenile idiopathic arthritis in Japan2012

    • Author(s)
      Yokota S, Imagawa T, Murata T, Tomiita M, Itoh Y, Fujikawa S, Takei S, Mori M.
    • Journal Title

      Mod Rheumatol

      Volume: 22(4) Issue: 4 Pages: 491-7

    • DOI

      10.1007/s10165-011-0561-1

    • NAID

      10031026845

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591546
  • [Journal Article] Radiologic analysis of the effect of tocilizumab on hands and large joints in children with systemic juvenile idiopathic arthritis2012

    • Author(s)
      Inaba Y, Ozawa R, Aoki C, Imagawa T, Mori M, Hara R, Miyamae T, Saito T, Yokota S
    • Journal Title

      Mod Rheumatol

      Volume: -

    • NAID

      10031189160

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591546
  • [Journal Article] Definitive differences inn laboratory and radiological characteristics between two subtypes of juvenile idiopathic arthritis:systemic arthiritis and polyarthritis2011

    • Author(s)
      Ozawa R,Inaba Y,Mori M,Hara R,Kikuchi M,Miyamae T,Imagawa T,Yokota s
    • Journal Title

      Mod Rheumatol

      Volume: -

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591546
  • [Journal Article] 小児シェーグレン症候群における小唾液腺組織の経時的変化を観察しえた8例の経験.2009

    • Author(s)
      岩田直美, 宮前多佳子, 菊地雅子, 岸崇之, 原良紀, 金子詩子, 篠木敏彦, 今川智之, 稲山嘉明, 横田俊平
    • Journal Title

      日本臨床免疫学会会誌 32巻3号

      Pages: 195-200

    • NAID

      10025636516

    • Data Source
      KAKENHI-PROJECT-19390287
  • [Journal Article] Whole blood interferon-gamma assay for tuberculosis in children in Japan.2009

    • Author(s)
      Higuchi R, Mori M, Ozawa R, Miyamae T, Imagawa T, Nishimaki S, Mitsuda T, Aihara Y, Yokota S
    • Journal Title

      Pediatr Int. 51(1)

      Pages: 97-102

    • Data Source
      KAKENHI-PROJECT-19390287
  • [Journal Article] 日本小児リウマチ学会:若年性特発性関節炎に対する生物学的製剤治療の手引き2009エタネルセプト.2009

    • Author(s)
      横田俊平, 森雅亮, 今川智之, 村田卓士, 冨板美奈子, 伊藤保彦, 藤川敏, 武井修治
    • Journal Title

      日本小児科学会雑誌 113巻8号

      Pages: 1344-1352

    • Data Source
      KAKENHI-PROJECT-19390287
  • [Journal Article] 【ステロイド薬の上手な使い方】ステロイド薬の使用方法、減量方法.2009

    • Author(s)
      今川智之
    • Journal Title

      小児内科 41巻5号

      Pages: 726-729

    • Data Source
      KAKENHI-PROJECT-19390287
  • [Journal Article] The role of heme oxygenase-1 in systemic-onset juvenile idiopathic arthritis.2009

    • Author(s)
      Takahashi A, Mori M, Naruto T, Nakajima S, Miyamae T, Imagawa T, Yokota S
    • Journal Title

      Mod Rheumatol. 19(3)

      Pages: 302-8

    • NAID

      10025113098

    • Data Source
      KAKENHI-PROJECT-19390287
  • [Journal Article] Interleukin-6 inhibits early differentiation of ATDC5 chondrogenic progenitor cells2009

    • Author(s)
      Shoko Nakajima, Takuya Naruto, Takako Miyamae, Tomoyuki Imagawa, Masaaki Mori, Shigeru Nishimaki, Shumpei Yokota
    • Journal Title

      Cytokine (CYTO-09-49R1) (accepted, in print)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591197
  • [Journal Article] 【小児リウマチ性疾患をどう診るか変貌した一次医療と専門医療】若年性特発性関節炎難治例に対するIL-6阻害薬.2009

    • Author(s)
      今川智之
    • Journal Title

      小児科臨床 62巻9号

      Pages: 1995-2002

    • Data Source
      KAKENHI-PROJECT-19390287
  • [Journal Article] Intravenous methylprednisolone pulse therapy for children with autoimmune hepatitis.2006

    • Author(s)
      Sogo T, Fujisawa T, Inui A, Komatsu H, Etani Y, Tajiri H, Waki K, Shimizu Y, Nakashima S, Imagawa T, Yokota S.
    • Journal Title

      Hepatology Research 34

      Pages: 187-187

    • NAID

      10020405456

    • Data Source
      KAKENHI-PROJECT-17790715
  • [Journal Article] Serum protein profile in systemic-onset juvenile idiopathic arthritis differentiates response versus nonresponse to therapy.2005

    • Author(s)
      Miyamae T, Malehorn DE, Lemster B, Mori M, Imagawa T, Yokota S, Bigbee WL, Welsh M, Klarskov K, Nishomoto N, Vallejo AN, Hirsch R
    • Journal Title

      Arthritis Research & Therapy 7

      Pages: 746-746

    • Data Source
      KAKENHI-PROJECT-17790715
  • [Journal Article] Clinical study of tocilizumab in children with systemic-onset juvenile idiopathic arthritis.2005

    • Author(s)
      Shumpei Yokota, Takako Miyamae, Tomoyuki Imagawa, Shigeki Katakura, Rumiko Kurosawa, Masaaki Mori.
    • Journal Title

      Clin Rev Allergy Immunol. 28・3

      Pages: 231-238

    • Data Source
      KAKENHI-PROJECT-16390305
  • [Journal Article] Tocilizumab, Anti-IL-6 Receptor Monoclonal Antibody : Randomized, Double-blind, Placebo-controlled, Withdrawal Phase III Trial of Efficacy and Safety against Systemic-onset Juvenile Idiopathic Arthritis

    • Author(s)
      Yokota S, Imagawa T.
    • Journal Title

      NEJM (in print)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390305
  • [Presentation] Effect of Anakinra on arthlopathy in CINCA/NOMID syndrome.2009

    • Author(s)
      Takako Miyamae, Yutaka Inaba, Takayuki Kishi, Utakako Kaneko, Tomoyuki Imagawa, Shumpei Yokota
    • Organizer
      The European League Against Rheumatism, The Annual European Congress of Rheumatology
    • Place of Presentation
      Copenhagen
    • Data Source
      KAKENHI-PROJECT-19390287
  • [Presentation] Effect of Anakinra on arthlopathy in CINCA/NOMID syndrome.2009

    • Author(s)
      Takako Miyamae, Yutaka Inaba, Takayuki Kishi, Utakako Kaneko, Tomoyuki Imagawa, Shumpei Yokota
    • Organizer
      World Congress on Inflammation
    • Place of Presentation
      Tokyo
    • Data Source
      KAKENHI-PROJECT-19390287
  • [Presentation] The Peripheral Blood Genes That Account for Predictability of Clinical Response to Tocilizumab (TCZ) Treatment, Corticosteroid Dose Reduction, and Serum IL-6 Normalization at Week 48 On Systemic Onset Juvenile Idiopathic Arthritis (sJIA) Patients.2009

    • Author(s)
      Norihiro Nishimoto, Yuichi Kawata, Hooi-Ming Lee, Chieko Aoki, Yasuo Adachi, Hidehiko Sugino, Tomoyuki Imagawa, Masaaki Mori, Minako Tomiita, Naomi Iwata, Takuji Murata, Mari Miyoshi, Syuji Takei, Yukoh Aihara, Takahiro Ochi, Shumpei Yokota
    • Organizer
      American College of Rheumatology, annual scientific meeting
    • Place of Presentation
      Philadelphia
    • Data Source
      KAKENHI-PROJECT-19390287
  • [Presentation] Drug-Free Remission of Patients with Systemic Juvenile Idiopathic Arthritis Receiving Tocilizumab for Treatment.2009

    • Author(s)
      Shumpei Yokota, Takuma Hara, Masako Kikuchi, Takayuki Kishi, Ryoki Hara, Rumiko Kurosawa, Remi Ozawa, Takako Miyamae, Tomoyuki Imagawa, Masaaki Mori
    • Organizer
      American College of Rheumatology, annual scientific meeting
    • Place of Presentation
      Philadelphia
    • Data Source
      KAKENHI-PROJECT-19390287
  • [Presentation] Clinical Analysis of Juvenile Dermatomyositis; A Retrospective Study of 45 Japanese.2009

    • Author(s)
      Takayuki Kishi, Masako Kikuchi, Ryoki Hara, Utako Kaneko, Toshihiko Shinoki, Takako Miyamae, Tomoyuki Imagawa, Masaaki Mori, Shumpei Yokota
    • Organizer
      The European League Against Rheumatism, The Annual European Congress of Rheumatology
    • Place of Presentation
      Copenhagen
    • Data Source
      KAKENHI-PROJECT-19390287
  • [Presentation] EFFECTS OF TOCILIZUMAB ON RADIOLOGICAL FINDINGS IN POLYARTICULAR JUVENILE IDIOPATHIC ARTHRITIS.2009

    • Author(s)
      Chie Aoki, Yutaka Inaba, Remi Ozawa, Tomoyuki Imagawa, Takako Miyamae, Masaaki Mori, Tomoyuki Saito, Shumpei Yokota
    • Organizer
      The European League Against Rheumatism, The Annual European Congress of Rheumatology
    • Place of Presentation
      Copenhagen
    • Data Source
      KAKENHI-PROJECT-19390287
  • [Presentation] RADIOLOGIC EVALUATION OF LARGE JOINTS DURING TOCILIZUMAB TREATMENT IN CHILDREN WITH SYSTEMIC JUVENILE IDIOPATHIC ARTHRITIS.2009

    • Author(s)
      Yutaka Inaba, Chie Aoki, Remi Ozawa, Tomoyuki Imagawa, Takako Miyamae, Masaaki Mori, T. omoyuki Saito1, Shumpei Yokota
    • Organizer
      The European League Against Rheumatism, The Annual European Congress of Rheumatology
    • Place of Presentation
      Copenhagen
    • Data Source
      KAKENHI-PROJECT-19390287
  • [Presentation] SAFETY AND EFFICACY OF UP TO THREE YEARS OF CONTINUOUS TOCILIZUMAB THERAPY IN CHILDREN WITH SYSTEMIC-ONSET JUVENILE IDIOPATHIC ARTHRITIS.2009

    • Author(s)
      Shumpei Yokota, Tomoyuki Imagawa, Takako Miyamae, Takayuki Kishi, Utako Kaneko, Norihiro Nishimoto, Tadamitsu KIshimoto
    • Organizer
      The European League Against Rheumatism, The Annual European Congress of Rheumatology
    • Place of Presentation
      Copenhagen
    • Data Source
      KAKENHI-PROJECT-19390287
  • [Presentation] DISCREPANCY BETWEEN PROGRESSION OF JOINT DAMAGE AND IMPROVEMENT OF SYSTEMIC INFLAMMATION IN PATIENTS WITH SYSTEMIC-ONSET JUVENILE IDIOPATHIC ARTHRITIS TREATED WITH TOCILIZUMAB.2009

    • Author(s)
      Utako Kaneko, Tomoyuki Imagawa, Takayuki Kishi, Masako Kikuchi, Ryoki Hara, T. oshihiko Shinoki, Takako Miyamae, Masaaki Mori, Shumpei Yokota
    • Organizer
      The European League Against Rheumatism, The Annual European Congress of Rheumatology
    • Place of Presentation
      Copenhagen
    • Data Source
      KAKENHI-PROJECT-19390287
  • [Presentation] Long-term Safety And Efficacy Of Tocilizumab In Patients With Systemic Juvenile Idiopathic Arthritis (JIA) Under The Extension And Long-term Trials2008

    • Author(s)
      Shumpei Yokotal, Tomoyuki Imagawal, Takako Miyamael, Masaaki Mori, et al.
    • Organizer
      米国リウマチ学会
    • Place of Presentation
      米国、サンフランシスコ
    • Year and Date
      2008-10-24
    • Data Source
      KAKENHI-PROJECT-19390287
  • 1.  YOKOTA Shumpei (10158363)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 26 results
  • 2.  MORI Masaaki (30254204)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 12 results
  • 3.  NARUTO Takuya (60438124)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 4.  MIYAMAE Takako (90322354)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 5.  KIKUCHI Masako (90555129)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 6.  NOZAWA Tomo (10588106)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  MITSUDA Toshihiro (00264672)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  片倉 茂樹 (30347314)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  KAWAI Shinichi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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