NAKASHIMA Naomi 中島尚美

Researcher Number	20337330
Other IDs
Affiliation (based on the past Project Information) *help	2013: 自治医科大学, 医学部, 助教 2010 – 2012: 自治医科大学, 医学部, 講師 2007 – 2009: Jichi Medical University, 医学部, 助教 2002 – 2006: 自治医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Pediatrics Except Principal Investigator Pediatrics / Pediatrics
Keywords	Principal Investigator 自閉性障害 / シナプス機能関連遺伝子 / シナプス機能関連 / CGH法 / CNV / CGH 法 / シナプス関連遺伝子 / エピジェネディクス機構 / MECP2 / 遺伝子不活化 … More / 遺伝的刷り込み現象 / エピジェネティクス機構 / DCA / 細胞内ATP / 電子伝達系 / Leigh症候群 … More Except Principal Investigator FOXP2 / MBD1 / セクレチン受容体 / セクレチン / 自閉性障害 / 自閉症 / Knockout mouse / secretin receptor / secretin / Autism / セクレチン受容体ノックアウトマウス / ノックアウトマウス / モデルマウス / 候補遺伝子解析 / CNV / 病因遺伝子 / シナプス足場蛋白 / コピー数多型（CNV) / マイクロアレーCGH / G蛋白結合型受容体 / シナプス / LIN7 / 足場蛋白 / 遺伝子変異 / コピー数多型 / 自閉症スペクトラム障害 / Rett症候群 / DLX6 / DLX5 / MECP2 / エピジェネティクス Less

Analysis for the pathogenesis and the target molecules of treatment for autism focusing on G-protein coupled receptors and synaptic molecules
- Principal Investigator
  
  YAMAGATA Takanori
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Jichi Medical University
Exhaustive gene expression analysis of the candidate genes related to pathology of autism spectrum disorderPrincipal Investigator
- Principal Investigator
  
  NAKASHIMA Naomi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  Jichi Medical University
Expression, inactivation and mutation analysis of the candidate genes for AutismPrincipal Investigator
- Principal Investigator
  
  NAKASHIMA Naomi
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  Jichi Medical University
candidate gene analysis for autism focusing on the epigenetic mechanism
- Principal Investigator
  
  YAMAGATA Takanori
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Jichi Medical University
Leigh症候群リンパ球における細胞学的特性の検討Principal Investigator
- Principal Investigator
  
  中島尚美
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  Jichi Medical University
Identification for the genes of autism by the analysis of neuronal peptides and linkage analysis.
- Principal Investigator
  
  YAMAGATA Takanori
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Jichi Medical University

All 2013 2011 2010 2009 2008 2007 2006 Other

All Journal Article Presentation

[Journal Article] An Xp22.12 microduplication including RPS6KA3 identified in a family with variably affected intellectual and behavioral disabilities2013
- Author(s)
  Matsumoto A, Kuwajima M, Miyake K, Kojima K, Nakashima N, Jimbo EF, Kubota T, Momoi MY, Yamagata T
- Journal Title
  
  J Hum Genet
  
  Volume: 58 Issue: 11 Pages: 755-757
- DOI
  10.1038/jhg.2013.88
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390275
[Journal Article] Clinical spectrum of early onset epileptic encephalopathies caused by KCNQ2 mutation2013
- Author(s)
  Kato M, …Saitsu H.
- Journal Title
  
  Epilepsia
  
  Volume: in press Issue: 7 Pages: 1282-7
- DOI
  10.1111/epi.12200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22689011, KAKENHI-PROJECT-23390275, KAKENHI-PLANNED-24118007, KAKENHI-PROJECT-24249019, KAKENHI-PROJECT-24591500, KAKENHI-PROJECT-24791060, KAKENHI-PROJECT-25293085, KAKENHI-PROJECT-25293235, KAKENHI-PROJECT-25860915
[Journal Article] Expression analysis and mutation detection of DLX5 and DLX6 in Autism.2010
- Author(s)
  Naomi Nakashima, Takanori Yamagata, Mariko Y. Momoi, 他3名(3番目～5番目)
- Journal Title
  
  Brain & Development 32
  
  Pages: 98-104
- NAID
  10027212757
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790739
[Journal Article] Expression analysis and mutation detection of DLX5 and DLX6 in autism2010
- Author(s)
  Naomi Nakashima, et al.
- Journal Title
  
  Brain & Development 32
  
  Pages: 98-104
- NAID
  10027212757
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790739
[Journal Article] Expression analysis and mutation detection of DLX5 and DLX6 in autism.2009
- Author(s)
  Nakashima N, Yamagata T, et al.
- Journal Title
  
  Brain and Development (In press)
- NAID
  10027212757
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591165
[Journal Article] Expression analysis and mutation detection of DLX5 and DLX6 in autism.2009
- Author(s)
  Nakashima N, Yamagata T, Mori M, Kuwajima M, Suwa K, Momoi MY.
- Journal Title
  
  Brain Dev. In press
- NAID
  10027212757
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591165
[Journal Article] Expression analysis and mutation detection of DLX5 and DLX6 in autism2009
- Author(s)
  Naomi Nakashima
- Journal Title
  
  Brain and Development (In press)
- NAID
  10027212757
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790739
[Journal Article] Familial analysis of mild intellectual disability and microduplication at Xp22.12 including RPS6KA3.
- Author(s)
  Matsumoto A, Kuwagima M, Miyake K, Kojima K, Nakashima N, Jimbo E, Kubota T, Momoi MY, Yamagata T
- Journal Title
  
  J Hum Genet submitted
  
  Volume: Xp22 Pages: 12-12
- Data Source
  KAKENHI-PROJECT-22790996
[Presentation] Deletion of MAOA and MAOB in male siblings with severe mental retardation and autistic phenotype2011
- Author(s)
  Saito M, Yamagata T, Shiba Y, Nakashima N, Nagashima M, Jimbo E, Momoi MY
- Organizer
  The 62rd Annual Meeting for the American Society of Human Genetics
- Place of Presentation
  Montreal
- Data Source
  KAKENHI-PROJECT-23390275
[Presentation] Deletion of MAOA and MAOB in male siblings with severe mental retardation and autistic phenotype2011
- Author(s)
  Saito M, Yamagata T, Shiba Y, Nakashima N, Nagashima M, Jimbo E, Momoi MY
- Organizer
  第12回国際人類遺伝学会
- Place of Presentation
  モントリオールコンベンションセンター(カナダ)
- Year and Date
  2011-10-12
- Data Source
  KAKENHI-PROJECT-22790996
[Presentation] Duplication of GPC3 in the boy with growth retardation and developmental delay2011
- Author(s)
  中島尚美
- Organizer
  第12回国際人類遺伝学会
- Place of Presentation
  モントリオールコンベンションセンター(カナダ)
- Year and Date
  2011-10-13
- Data Source
  KAKENHI-PROJECT-22790996
[Presentation] Duplication of GPC3 in the boy with growth retardation and developmental delay2011
- Author(s)
  Nakashima N, Yamamgata T, Saito M, Nozaki Y, Momoi MY
- Organizer
  The 61st Annual Meeting of the American Society of Human Genetics
- Place of Presentation
  Montreal, Canada
- Year and Date
  2011-11-14
- Data Source
  KAKENHI-PROJECT-23390275
[Presentation] Deletion of MAOA and MAOB in male siblings with severe mental retardation and autistic phenotype2011
- Author(s)
  Saito M, Yamagata T, Shiba Y, Nakashima N, Nagashima M, Jimbo E, Momoi MY
- Organizer
  The 61st Annual Meeting of the American Society of Human Genetics
- Place of Presentation
  Montreal, Canada
- Year and Date
  2011-11-13
- Data Source
  KAKENHI-PROJECT-23390275
[Presentation] Duplication of GPC3 in the boy with growth retardation and developmental delay2011
- Author(s)
  中島尚美
- Organizer
  第12回国際人類遺伝学会,モント
- Place of Presentation
  リオール(カナダ)
- Year and Date
  2011-10-13
- Data Source
  KAKENHI-PROJECT-22790996
[Presentation] Deletion of MAOA and MAOB in male siblings with severe mental retardation and autistic phenotype2011
- Author(s)
  Saito M, Yamagata T, Shiba Y, Nakashima N, Nagashima M, Jimbo E, Momoi MY
- Organizer
  第12回国際人類遺伝学会
- Place of Presentation
  リオール(カナダ)
- Year and Date
  2011-10-13
- Data Source
  KAKENHI-PROJECT-22790996
[Presentation] Genes relating to synaptogenesis located on 7q31 as Candidate genes for Autism2008
- Author(s)
  Naomi Nakashima
- Organizer
  第58回アメリカ人類遺伝学会
- Place of Presentation
  米国(ペンシルバニア州フィラデルフィア)
- Year and Date
  2008-11-12
- Data Source
  KAKENHI-PROJECT-19790739
[Presentation] Genes relating synaps in 7q31 as Candidate genes for Autism.2008
- Author(s)
  Nakashima N, Yamagata T, et al
- Organizer
  The 58th Annual Meeting for the American Society of Human Genetics.
- Place of Presentation
  Philaderphia
- Year and Date
  2008-11-14
- Data Source
  KAKENHI-PROJECT-18591165
[Presentation] Gene relating to synaptogenesis located on 7q31 as Candidate gene for Autism.2008
- Author(s)
  Naomi Nakashima
- Organizer
  第58回アメリカ人類遺伝学会
- Place of Presentation
  米国(フィラデルフィア)
- Year and Date
  2008-11-12
- Data Source
  KAKENHI-PROJECT-19790739
[Presentation] Genes relating synaps in 7q31 as Candidate genes for Autism.2008
- Author(s)
  Nakashima N, Yamagata T, et al.
- Organizer
  58^<th> Annual Meeting of American Society of Human Genetics
- Place of Presentation
  Philadelphia
- Year and Date
  2008-11-14
- Data Source
  KAKENHI-PROJECT-18591165
[Presentation] Genes regulated by MECP2 as candidate genes for autism2007
- Author(s)
  中島尚美
- Organizer
  第57回アメリカ人類遺伝学会
- Place of Presentation
  米国(サンディエゴ)
- Year and Date
  2007-10-26
- Data Source
  KAKENHI-PROJECT-19790739
[Presentation] Genes regulated by MECP2 as candidate genes for autism2007
- Author(s)
  N.Nakashima,T.Yamagata,Z.Yu,K.Suwa,M.Mori,andM.Y.Momoi.
- Organizer
  Annual Meeting of American Society of Human Genetics
- Place of Presentation
  San Diego
- Year and Date
  2007-10-25
- Data Source
  KAKENHI-PROJECT-18591165
[Presentation] Genes regulated by MECP2 as candidate genes for autism.2007
- Author(s)
  Naomi Nakashima
- Organizer
  第57回アメリカ人類遺伝学会
- Place of Presentation
  米国(サンディエゴ)
- Year and Date
  2007-10-26
- Data Source
  KAKENHI-PROJECT-19790739
[Presentation] Imprinted genes relating with MECP2 in 7q21 are not major causative genes for autism.2006
- Author(s)
  Nakashima N, Yamagata T, et al
- Organizer
  The 56th Annual Meeting for the American Society of Human Genetics.
- Place of Presentation
  New Orleans
- Year and Date
  2006-10-10
- Data Source
  KAKENHI-PROJECT-18591165

1. MORI Masato (10337347)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
2. YAMAGATA Takanori (00239857)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
3. KUWAJIMA Mari (30398515)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. NAGATA Kouichi (50252143)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. NOZAKI Yasuyuki (90281295)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. MONDEN Yukifumi (80382951)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. NAGASHIMA Masako (70438662)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. JINBO Eriko (20291651)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. SUWA Kiyotaka (30285796)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. FUJITA Eriko

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
11. 才津浩智

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

NAKASHIMA Naomi 中島 尚美

Research Projects

Research Products

Co-Researchers

Analysis for the pathogenesis and the target molecules of treatment for autism focusing on G-protein coupled receptors and synaptic molecules

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Exhaustive gene expression analysis of the candidate genes related to pathology of autism spectrum disorderPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Expression, inactivation and mutation analysis of the candidate genes for AutismPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

candidate gene analysis for autism focusing on the epigenetic mechanism

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Leigh症候群リンパ球における細胞学的特性の検討Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification for the genes of autism by the analysis of neuronal peptides and linkage analysis.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] An Xp22.12 microduplication including RPS6KA3 identified in a family with variably affected intellectual and behavioral disabilities2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Clinical spectrum of early onset epileptic encephalopathies caused by KCNQ2 mutation2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Expression analysis and mutation detection of DLX5 and DLX6 in Autism.2010

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Expression analysis and mutation detection of DLX5 and DLX6 in autism2010

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Expression analysis and mutation detection of DLX5 and DLX6 in autism.2009

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Expression analysis and mutation detection of DLX5 and DLX6 in autism.2009

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Expression analysis and mutation detection of DLX5 and DLX6 in autism2009

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Familial analysis of mild intellectual disability and microduplication at Xp22.12 including RPS6KA3.

Author(s)

Journal Title

Data Source

[Presentation] Deletion of MAOA and MAOB in male siblings with severe mental retardation and autistic phenotype2011

NAKASHIMA Naomi 中島尚美