Sai Sei 佐井星

… Alternative Names

SAI SEI 崔星

CUI Xing 崔星

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Researcher Number	20342735
Other IDs
Affiliation (Current)	2025: 国立研究開発法人量子科学技術研究開発機構, QST病院重粒子線治療研究部, 上席研究員 2025: 国立研究開発法人量子科学技術研究開発機構, 量子医科学研究所重粒子線治療研究部, 上席研究員
Affiliation (based on the past Project Information) *help	2015: 放射線医学総合研究所, 主任研究員 2012 – 2014: 独立行政法人放射線医学総合研究所, 重粒子医科学センター, 主任研究員 2002 – 2004: 独立行政法人国立環境研究所, 環境健康研究領域, 研究員 2002: 国立環境研究所, 環境健康研究領域, 研究員
Review Section/Research Field	Principal Investigator Radiation science / 環境影響評価(含放射線生物学) Except Principal Investigator Radiation science / 広領域
Keywords	Principal Investigator 重粒子 / 治癒率 / DNA損傷 / 細胞生存率 / 癌幹細胞 / 膵臓癌 / 炭素線 / 分子病理学 / DNA損傷と修復 / がん幹細胞 … More / 膵臓がん / 粒子線生物学 / ILK / cyclin D1 / マイクロアレイ / PTEN / E-cadherin / p16 / DNA methylation / 化学形態 / 癌 / 遺伝子活性化 / 砒素 … More Except Principal Investigator マウスモデル / 17AAG / ヒートショック蛋白90阻害剤 / DNA-PKcs / Ｘ線 / 相同組換修復 / Hsp90 阻害剤 / DNA損傷応答 / 併用療法 / Hsp90　阻害剤 / PU-H71 / 細胞老化 / 細胞周期 / DNA-PK阻害剤 / DNA二重鎖切断修復 / TAS-116 / 放射線増感 / 重粒子線 / Hsp90阻害剤 / Single nucleotide polymorphism / RNA interference / Arsenicals / Urban particles / Heme oxigenase-1 / Cytotoxicity / Glutathione / Oxidative stress / 肺胞II型上皮細胞 / 砒素 / 粒子状物質 / 感受性 / 抗酸化酵素 / ヘムオキシゲナーゼ / cDNAアレー / 内皮細胞 / 細胞II型上皮細胞 / 血管内皮細胞 / 一塩基多型 / RNA干渉 / ヒ素化合物 / 都市大気粒子 / ヘムオキシゲナーゼ-1 / 細胞毒性 / グルタチオン / 酸化ストレス Less

Basic Research on Gastrointestinal Cancer Stem Cell Targeting Therapy with Heavy Ion BeamsPrincipal Investigator
- Principal Investigator
  
  SAI SEI
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  National Institute of Radiological Sciences
Basic research to explore factors to improve effectiveness of radiation therapy
- Principal Investigator
  
  OKAYASU RYUICHI
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Radiation science
- Research Institution
  National Institute of Radiological Sciences
cDNAマイクロアレイによる新規ヒ素発癌関連遺伝子の同定Principal Investigator
- Principal Investigator
  
  崔星
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  National Institute for Environmental Studies
Determination of genetic susceptibility factors for atmospheric toxic substances.
- Principal Investigator
  
  HIRANO Seishiro
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  広領域
- Research Institution
  National Institute for Environmental Studies

All 2015 2014 2013 2012 2005 2004 2003 Other

All Journal Article Presentation

[Journal Article] The complexity of DNA double strand break is a crucial factor for activating ATR signaling pathway for G2/M checkpoint regulation regardless of ATM function2015
- Author(s)
  Xue L, Furusawa Y, Okayasu R, Miura M, Cui X, Liu C, Hirayama R, Matsumoto Y, Yajima H, Yu D.
- Journal Title
  
  DNA Repair
  
  Volume: 25 Pages: 72-83
- DOI
  10.1016/j.dnarep.2014.11.004
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24249067, KAKENHI-PROJECT-25340042, KAKENHI-PROJECT-26293399, KAKENHI-PROJECT-15K09986
[Journal Article] Combination of Carbon Ion Beam and Gemcitabine Causes Unreparable DNA Damage and Death of Radioresistant Pancreatic Cancer Stem-Like Cells In Vitro and In Vivo2015
- Author(s)
  Sai S, Wakai T, Vares G, Yamada S, Kamijo T, Kamada T, and Shirai T. Combination of Carbon Ion Beam and Gemcitabine Causes Unreparable DNA Damage and Death of Radioresistant Pancreatic Cancer Stem-Like Cells In Vitro and In Vivo
- Journal Title
  
  Oncotarget
  
  Volume: 6 Pages: 5517-5535
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24591858
[Journal Article] Progesterone generates cancer stem cells through membrane progesterone receptor-triggered signaling in basal-like human mammary cells2015
- Author(s)
  Vares G, Sai S, Wang B, Fujimori A, Nenoi M, Nakajima T.
- Journal Title
  
  Cancer Letter
  
  Volume: 362 Issue: 2 Pages: 167-173
- DOI
  10.1016/j.canlet.2015.03.030
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24591858, KAKENHI-PROJECT-24710066, KAKENHI-PROJECT-25340041
[Journal Article] The complexity of DNA double strand break is a crucial factor for activating ATR signaling pathway for G2/M checkpoint regulation regardless of ATM function.2015
- Author(s)
  Xue L, Furusawa Y, Okayasu R, Miura M, Cui X et al.
- Journal Title
  
  DNA Repair
  
  Volume: 25 Issue: 3 Pages: 72-83
- DOI
  10.1104/pp.114.255430
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24591858
[Journal Article] Arsenite induces premature senescence via p53/p21 pathway as a result of DNA damage in human malignant glioblastoma cells.2014
- Author(s)
  Ninomiya Y, Cui X*, Yasuda T, Wang B, Yu D, Suzuki-Sekine E, and Nenoi M.
- Journal Title
  
  BMB Reports
  
  Volume: 6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591858
[Journal Article] Generation of breast cancer stem cells by steroid hormones in irradiated human mammary cell lines.2013
- Author(s)
  Vares G, Cui X, Wang B, Nakajima T, Nenoi M.
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 10 Pages: e77124-e77124
- DOI
  10.1371/journal.pone.0077124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591858, KAKENHI-PROJECT-24710066
[Journal Article] Parg Deficiency Confers Radio-sensitization through Enhanced Cell Death in Mouse ES Cells Exposed to Various Forms of Ionizing Radiation.2013
- Author(s)
  Shirai H, Fujimori H, Gunji A, Maeda D, Hirai T, Poetsch AR, Harada H, Yoshida T, Sasai K, Okayasu R, Masutani M.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: Epub ahead of print Issue: 1 Pages: 100-106
- DOI
  10.1016/j.bbrc.2013.04.048
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300343, KAKENHI-PROJECT-24249067, KAKENHI-PROJECT-24890233
[Journal Article] Different effects of carbon ion beams and X-rays on clonogenic survival and DNA repair in human pancreatic cancer stem-like cells.2012
- Author(s)
  Oonishi K, Cui X, Hirakawa H, Fujimori A, Kamiio T, Yamada S, Yokosuka O, Kamada T.
- Journal Title
  
  Radiother Oncol.
  
  Volume: 105 Issue: 2 Pages: 258-265
- DOI
  10.1016/j.radonc.2012.08.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390269, KAKENHI-PROJECT-24591858
[Journal Article] Stability of arsenic metabolites, arsenic triglutathione [As(GS)_3] and methylarsenic diglutathione [CH_3As(GS)_2], in rat bile.2005
- Author(s)
  Y.Kobayashi, X.Cui, S.Hirano
- Journal Title
  
  Toxicology 211
  
  Pages: 115-123
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14390058
[Journal Article] Stability of arsenic metabolites, arsenic triglutathine [As(GS)_3] and methylarsenic diglutathione [CH_3As(GS)_2], in rat bile.2005
- Author(s)
  Y.Kobayashi, X.Cui, S.Hirano
- Journal Title
  
  Toxicology 211
  
  Pages: 115-123
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14390058
[Journal Article] A new metabolic pathway of arsenite : Arsenic-glutathione complexes are substrates for human arsenic methyltransferase Cyt19.2005
- Author(s)
  T.Hayakawa, Y.Kobayashi, X.Cui, S.Hirano
- Journal Title
  
  Arch. Toxicol 79
  
  Pages: 183-191
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14390058
[Journal Article] A new metabolic pathway of arsenite : Arsenic-glutathione complexes are substrates for human arsenic methyltransferase Cyt19.2005
- Author(s)
  T.Hayakawa, Y.Kobayashi, X.Cui, S.Hirano
- Journal Title
  
  Arch.Toxicol. 79
  
  Pages: 183-191
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14390058
[Journal Article] Accumulation and toxicity of monophenyl arsenicals in rat endothelial cells.2005
- Author(s)
  S.Hirano, Y.Kobayashi, T.Hayakawa, X.Cui, M.Yamamoto, S.Kanno, A.Shraim
- Journal Title
  
  Arch.Toxicol. 79
  
  Pages: 54-61
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14390058
[Journal Article] Accumulation and toxicity of monophenyl arsenicals in rat endothelial cells.2005
- Author(s)
  S.Hirano, Y.Kobayashi, T.Hayakawa, X.Cui, M.Yamamoto, S.Kanno, A.Shraim
- Journal Title
  
  Arch. Toxicol. 79
  
  Pages: 54-61
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14390058
[Journal Article] Accumulation and toxicity of monophenyl in rat endothelial cells2005
- Author(s)
  S.Hirano, Y.Kobayashi, T.Hayakawa, X.Cui, M.Yamamoto, S.Kanno, A.Shraim
- Journal Title
  
  Arch. Toxicol. 79
  
  Pages: 54-61
- Data Source
  KAKENHI-PROJECT-14390058
[Journal Article] A new metabolic pathway of arsenite : arsenic-glutathione complexes are substrates for human aresenic methyltransferae Cyt192005
- Author(s)
  T.Hayakawa, Y.Kobayashi, X.Cui, S.Hirano
- Journal Title
  
  Arch. Toxicol. (印刷中)
- Data Source
  KAKENHI-PROJECT-14390058
[Journal Article] The accumulation and toxicity of methylated arsenicals in endothelial cells : Important roles of thiol compounds.2004
- Author(s)
  S.Hirano, Y.Kobayashi, X.Cui, S.Kanno, T.Hayakawa, A.Shrim
- Journal Title
  
  Toxicol.Appl.Pharmacol. 198
  
  Pages: 458-467
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14390058
[Journal Article] Arsenic speciation in bile and urine following oral and intravenous exposure to inorganic and organic arsenics in rats.2004
- Author(s)
  X.Cui, Y.Kobayashi, T.Hayakawa, S.Hirano
- Journal Title
  
  Toxicol Sci. 82
  
  Pages: 478-487
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14390058
[Journal Article] The accumulation and toxicity of methylated arsenicals in sndothelial cells : Important roles of thiol compounds2004
- Author(s)
  S.Hirano, Y.Kobayashi, X.Cui, S.Kannno, T.Hayakawa, A.Shraim
- Journal Title
  
  Toxicol. Appl. Pharmacol. 198
  
  Pages: 458-467
- Data Source
  KAKENHI-PROJECT-14390058
[Journal Article] Arsenic speciation in bile and urine following oral and intravenous exposure to inorganic and organic arsenics in rats2004
- Author(s)
  X.Cui, Y.Kobayashi, T.Hayakawa, S.Hirano
- Journal Title
  
  Toxicol Sci. 82
  
  Pages: 478-487
- Data Source
  KAKENHI-PROJECT-14390058
[Journal Article] Arsenic speciation in bile and urine following oral and intravenous exposure to inorganic and organic arsenics in rats.2004
- Author(s)
  X.Cui, Y.Kobayashi, T.Hayakawa, S.Hirano
- Journal Title
  
  Toxicol. Sci. 82
  
  Pages: 478-487
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14390058
[Journal Article] The accumulation and toxicity of methylated arsenicals in endothelial cells : Important roles of thiol compounds.2004
- Author(s)
  S.Hirano, Y.Kobayashi, X.Cui, S.Kanno, T.Hayakawa, A.Shraim
- Journal Title
  
  Toxicol. Appl. Pharmacol. 198
  
  Pages: 458-467
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14390058
[Journal Article] The Difference in Uptake and Toxicity of Trivalent and Pentavalent Inorganic Arsenics in Rat Heart Microvessel Endothelial Cells.2003
- Author(s)
  S.Hirano, X.Cui, S.Li, S.Kanno, Y.Kobayashi, T.Hayakawa, A.Shraim
- Journal Title
  
  Arch. Toxicol. 77
  
  Pages: 305-312
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14390058
[Journal Article] Arsenic speciation in the urine and hair of individuals exposed toair borne arsenic through coal-burning in Guizhou, PR China.2003
- Author(s)
  A.Shraim, X.Cui, S.Li, J.Ng, J.Wang, Y.Jin, Y.Liu, L.Guo, D.Li, S.Wang, R.Zhang, S.Hirano
- Journal Title
  
  Toxicol. Lett. 137
  
  Pages: 35-48
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14390058
[Journal Article] Arsenic speciation in the urine and hair of individuals exposed to airborne arsenic through coal-burning in Guizhou, PR China.2003
- Author(s)
  A.Shraim, X.Cui, S.Li, J.Ng, J.Wang, Y.Jin, Y.Liu, L.Guo, D.Li, S.Wang, R.Zhang, S.Hirano
- Journal Title
  
  Toxicol.Lett. 137
  
  Pages: 35-48
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14390058
[Journal Article] The Difference in Uptake and Toxicity of Trivalent and Pentavalent Inorganic Arsenics in Rat Heart Micro vessel Endothelial Cells.Arch.2003
- Author(s)
  S.Hirano, X.Cui, S.Li, S.Kanno, Y.Kobayashi, T.Hayakawa, A.Shraim
- Journal Title
  
  Toxicol. 77
  
  Pages: 305-312
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14390058
[Journal Article] PCR -based Subtraction Analyses for Upregulated Gene Transcription in Cadmium-exposed Rat Lung Type 2 Epithelial Cells.2003
- Author(s)
  S.Hirano, H.Kitajima, T.Hayakawa, X.Cui, S.Kanno, Y.Kobayashi, M.Yamamoto
- Journal Title
  
  Biochem.Biophys.Res.Commun. 308
  
  Pages: 133-138
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14390058
[Journal Article] PCR-based Subtraction Analyses for Upregulated Gene Transcription in Cadmium-exposed Rat Lung Type 2 Epithelial Cells.2003
- Author(s)
  S.Hirano, H.Kitajima, T.Hayakawa, X.Cui, S.Kanno, Y.Kobayashi, M.Yamamoto
- Journal Title
  
  Biochem. Biophys. Res. Commun. 308
  
  Pages: 133-138
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14390058
[Presentation] 重粒子線による癌幹細胞を標的とした癌治療の基礎的研究2013
- Author(s)
  崔星
- Organizer
  山梨大学医学部 (分子病理学講座)　にて
- Place of Presentation
  山梨県中央市
- Invited
- Data Source
  KAKENHI-PROJECT-24591858
[Presentation] 重粒子線による消化器癌幹細胞を標的とした癌治療の基礎的研究2013
- Author(s)
  崔星
- Organizer
  新潟大学医学部 (第一外科講座)　にて
- Place of Presentation
  新潟市
- Invited
- Data Source
  KAKENHI-PROJECT-24591858
[Presentation] 重粒子単独或はGemcitabine併用によるヒト膵癌幹細胞及び移植腫瘍抑制効果2013
- Author(s)
  崔星、若井俊文、趙　建東、山田滋、鎌田正
- Organizer
  第44回日本膵臓学会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-24591858
[Presentation] ヒト大腸癌細胞における癌幹細胞マーカー発現とXRCC4の役割2013
- Author(s)
  崔星
- Organizer
  第5回消化器疾患プロジェクト会議　2013年2月16日
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24591858
[Presentation] Effects of Carbon Ion Beam Alone or in Combination with Chk1 Inhibitor and Gemcitabine on Putative Pancreatic Cancer Stem Cells2013
- Author(s)
  Sei Sai, Toshiyuki Shirai, Tadashi Kamada
- Organizer
  International Association of Pancreatology (IAP) and Korean Pancreatobiliary Association (KPBA)
- Place of Presentation
  Seoul, Korea
- Data Source
  KAKENHI-PROJECT-24591858
[Presentation] X線単独或はCisplatinやChk1阻害剤併用によるTriple Negative乳癌幹細胞への影響2013
- Author(s)
  崔星、唐澤久美子、堀本義哉、Guillaume Vares、林光弘、白井敏之
- Organizer
  第26回日本放射線腫瘍学会
- Place of Presentation
  青森
- Data Source
  KAKENHI-PROJECT-24591858
[Presentation] Eradication of Gastrointestinal Cancer Stem Cells by Heavy Ion Radiotherapy2013
- Author(s)
  Sei Sai and Toshiyuki Shirai
- Organizer
  6th Annual World Congress of Regenerative Medicine & Stem Cells
- Place of Presentation
  Dalian, China
- Data Source
  KAKENHI-PROJECT-24591858
[Presentation] Defects in XRCC4 Alters Human Colon Cancer Stem Cell Markers and Enhances Its Radiosensitivity to X-ray and Carbon Ion Beam2013
- Author(s)
  Sei Sai, Toshifumi Wakai, Guillaume Vares, Bing Wang, Mitsuru Nenoi, Tekehiko Kamijo, Toshiyuki Shirai, and Tadashi Kamada
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24591858
[Presentation] Effects of Carbon Ion Beam Alone or in Combination with Sorafenib on Putative Liver Cancer Stem Cells2013
- Author(s)
  Sei Sai,Toshifumi Wakai, Jian-Dong Zhao, Toshiyuki Shirai, and Tadashi Kamada
- Organizer
  The 17th ECCO, 38th ESMO, 32nd ESTRO European Cancer Congress
- Place of Presentation
  Amsterdam, Netherlands
- Data Source
  KAKENHI-PROJECT-24591858
[Presentation] 重粒子線単独或はSorafenibやChk1阻害剤併用による肝癌幹細胞への影響2013
- Author(s)
  崔星、若井俊文、白井敏之
- Organizer
  第56回放射線影響学会
- Place of Presentation
  青森
- Data Source
  KAKENHI-PROJECT-24591858
[Presentation] The Role of XRCC4 in Human Colon Cancer Stem Cell Properties and Radiosensitivity2013
- Author(s)
  Sei Sai, Toshifumi Wakai, Guillaume Vares, Tadashi Kamada.
- Organizer
  International Society for Stem Cell Research (ISSCR) 11 th Annual Meeting
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-24591858
[Presentation] Triple Negative乳癌幹細胞に対する重粒子とCisplatin、Chk1阻害剤併用による殺傷効果2013
- Author(s)
  崔星、堀本義哉、林光弘、唐澤久美子
- Organizer
  第10回日本乳癌学会・関東地方会
- Place of Presentation
  大宮
- Data Source
  KAKENHI-PROJECT-24591858
[Presentation] がんの親玉―がん幹細胞を狙い撃ちできる重粒子治療 ――消化器系がんを中心に2013
- Author(s)
  崔星
- Organizer
  東海がんプロフェッショナル養成基盤推進プランセミナー
- Place of Presentation
  名古屋
- Invited
- Data Source
  KAKENHI-PROJECT-24591858
[Presentation] Distinct Effects of Carbon Ion Beam and X-ray on Putative Liver Cancer Stem Cell In Vitro and In Vivo2013
- Author(s)
  Sei Sai, Toshifumi Wakai, Tadashi Kamada
- Organizer
  23rd Conference of the Asian Pacific Association for the Study of the Liver (APASL 2013)
- Place of Presentation
  Singapore
- Data Source
  KAKENHI-PROJECT-24591858
[Presentation] Carbon Ion Beams Are Effective in Targeting Cholangiocarcinoma Stem-Like Cells In Vitro and In Vivo2013
- Author(s)
  Sei Sai, Toshifumi Wakai, Jian-Dong Zhao,Shigeru Yamada, Tadashi Kamada
- Organizer
  Heavy Ion in Therapy and Space Radiation Symposium (HITSRS)
- Place of Presentation
  Chiba, Japan
- Data Source
  KAKENHI-PROJECT-24591858
[Presentation] Elimination of Cancer Stem Cells by Carbon Ion Beam ---A Promising New Strategy for Cancer Treatment2012
- Author(s)
  崔星
- Organizer
  韓国原子力研究院（KAERI）先端放射線技術研究所（ARTI）にて
- Place of Presentation
  井邑市, 韓国
- Invited
- Data Source
  KAKENHI-PROJECT-24591858
[Presentation] Elimination of Cancer Stem Cells by Carbon Ion Beam ---A Promising New Strategy for Cancer Treatment2012
- Author(s)
  崔星
- Organizer
  中国延辺大学付属病院にて
- Place of Presentation
  延吉市,　中国
- Invited
- Data Source
  KAKENHI-PROJECT-24591858
[Presentation] Effects of Carbon Ion Beams on Liver Cancer Stem-Like Cells and Its Comparison with X-rays.2012
- Author(s)
  Sei Sai, Kazuhiko Oonishi, Takehiko Kamijo, Shigeru Yamada, Tadashi Kamada
- Organizer
  International Society for Stem Cell Research (ISSCR) 10 th Annual Meeting
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-24591858
[Presentation] 重粒子線によるヒト肝癌幹細胞生存率及びDNA損傷への影響2012
- Author(s)
  崔星、山田滋、鎌田正
- Organizer
  第25回日本放射線腫瘍学会・　2012年11月23日～25日
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24591858
[Presentation] Identification of Cholangiocarcinoma Stem-Like Cells and Its Radiosensitivity to Carbon Ion Beams2012
- Author(s)
  Sei Sai, Toshifumi Wakai, Takehiko Kamijo,Shigeru Yamada, Tadashi Kamada
- Organizer
  第71回日本癌学会学術総会　2012年9月19日～21日
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24591858
[Presentation] 重粒子線による癌幹細胞を標的とした癌治療の基礎的研究2012
- Author(s)
  崔星、上條岳彦、山田滋、鎌田正
- Organizer
  日本放射線影響学会第55回大会2012年9月6日～8日
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-24591858
[Presentation] The Role of XRCC4 in Sensitizing Human Colon Cancer Stem-Like Cells to X-ray or Carbon Ion Beam2012
- Author(s)
  Sei Sai, Kazuhiko Oonishi, Masahiko Mori, Takehiko Kamijo, Shigeru Yamada, and Tadashi Kamada.
- Organizer
  ASTRO's 54th Annual Meeting　October 28 - 31, 2012
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-24591858
[Presentation] Effects of Carbon Ion Beam on Pancreatic Cancer Stem-Like Cells In Vitro and In Vivo2012
- Author(s)
  Sei Sai, Kazuhiko Oonishi, Takehiko Kamijo, Shigeru Yamada, Tadashi Kamada
- Organizer
  51st Annual Meeting of Particle Therapy Co-Operative Group (PTCOG51)
- Place of Presentation
  Goyang, Seoul, Korea
- Data Source
  KAKENHI-PROJECT-24591858
[Presentation] Eradication of Cancer Stem Cells by Heavy Ion Radiotherapy2012
- Author(s)
  崔星
- Organizer
  Columbia University Radiological Centerにて
- Place of Presentation
  NewYork, USA
- Invited
- Data Source
  KAKENHI-PROJECT-24591858
[Presentation] 重粒子線照射によるヒト膵癌幹細胞生存率、DNA修復及び移植腫瘍への影響2012
- Author(s)
  崔星、大西和彦、上條岳彦、山田滋、鎌田正.
- Organizer
  第43回日本膵臓学会・2012年6月28日～29日山形
- Place of Presentation
  山形市
- Data Source
  KAKENHI-PROJECT-24591858
[Presentation] 重粒子単独或はCisplatinとの併用によるTriple Negative乳癌幹細胞に対する細胞生存及びDNA損傷
- Author(s)
  崔星、唐澤久美子、堀本義哉、林光弘、白井敏之
- Organizer
  第22回日本乳癌学会
- Place of Presentation
  大阪
- Year and Date
  2014-07-10 – 2014-07-11
- Data Source
  KAKENHI-PROJECT-24591858
[Presentation] 炭素線とCisplatinとの併用によるTriple Negative乳癌幹細胞に対する細胞殺傷及びDNA損傷増感作用
- Author(s)
  崔星、唐澤久美子、堀本義哉、林光弘、白井敏之
- Organizer
  第17回癌治療増感シンポジウム
- Place of Presentation
  奈良
- Year and Date
  2015-02-06 – 2015-02-07
- Invited
- Data Source
  KAKENHI-PROJECT-24591858
[Presentation] 肝癌幹細胞に対する重粒子単独或はSorafenibとの併用による殺傷効果
- Author(s)
  崔星、若井俊文、上條岳彦、白井敏之
- Organizer
  第27回日本放射線腫瘍学会
- Place of Presentation
  横浜
- Year and Date
  2014-12-11 – 2015-12-13
- Data Source
  KAKENHI-PROJECT-24591858
[Presentation] ARTEMIS欠損によるヒト大腸癌幹細胞マーカー発現変化及びX線、炭素線に対する感受性増強
- Author(s)
  崔星、上條岳彦、若井俊文、白井敏之
- Organizer
  第73回日本癌学会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24591858
[Presentation] Combination of Carbon Ion Beam and Gemcitabine Causes Unrepairable DNA Damage and Death of Radioresistant Pancreatic Cancer Stem-Like Cells In Vitro and In Vivo
- Author(s)
  Sei Sai, Toshifumi Wakai, Guillaume Vares, Shigeru Yamada, Tadashi Kamada, and Toshiyuki Shirai
- Organizer
  AACR annual meeting
- Place of Presentation
  Philadelphia, USA
- Year and Date
  2015-04-18 – 2015-04-22
- Data Source
  KAKENHI-PROJECT-24591858
[Presentation] Pancreatic Cancer Stem-Like Cell Targeting Radiotherapy by Carbon Ion Beam Alone or in Combination with Gemcitabine
- Author(s)
  Sei Sai and Toshiyuki Shirai
- Organizer
  Korea Society of Radiation Bioscience (KSRB) Spring Conference
- Place of Presentation
  Busan, Korea
- Year and Date
  2015-05-07 – 2015-05-08
- Invited
- Data Source
  KAKENHI-PROJECT-24591858
[Presentation] 放射線抵抗性癌幹細胞に対する重粒子線単独或は抗癌剤との併用による細胞生存、DNA損傷、腫瘍抑制効果について
- Author(s)
  崔星
- Organizer
  第57回日本放射線影響学会
- Place of Presentation
  鹿児島
- Year and Date
  2015-10-01 – 2015-10-03
- Data Source
  KAKENHI-PROJECT-24591858
[Presentation] arbon Ion Beam Combined with Gemcitabine Remarkably Disrupts Pancreatic Cancer Stem-Like Cells via Complex DNA Double Strand Breaks (DSB) and Multiple Cell Death Pathways
- Author(s)
  Sei Sai and Toshiyuki Shirai
- Organizer
  46th Annual Meeting of the European Pancreatic Club
- Place of Presentation
  Southampton, UK
- Year and Date
  2014-06-25 – 2014-06-28
- Data Source
  KAKENHI-PROJECT-24591858
[Presentation] Cancer Stem Cell-Targeting Radiotherapy by Carbon Ion Beam Alone or in Combination with Molecular Targeting Drugs
- Author(s)
  Sei Sai and Toshiyuki Shirai
- Organizer
  The 2nd Global Chinese Congress of Radiation Research (GCCRR2014)
- Place of Presentation
  Suzhou, China
- Year and Date
  2014-05-11 – 2015-05-15
- Invited
- Data Source
  KAKENHI-PROJECT-24591858
[Presentation] Effects of Carbon Ion Beam Alone or in Combination with Cisplatin on Triple Negative Breast Cancer Stem-Like Cells
- Author(s)
  2.Sei Sai, Kumiko Karasawa, Guillaume Vares, Yoshiya Horimoto, Mitsuhiro Hayashi, and Toshiyuki Shirai
- Organizer
  AACR annual meeting
- Place of Presentation
  San Diego, USA
- Year and Date
  2014-04-04 – 2014-04-09
- Data Source
  KAKENHI-PROJECT-24591858

1. KAMIJO Takehiko (90262708)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
2. HIRANO Seishiro (20150162)

# of Collaborated Projects: 1 results

# of Collaborated Products: 20 results
3. OKAYASU RYUICHI (50356135)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. FUJIMORI Akira (50314183)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. YAJIMA Hirohiko (30261895)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. JEGGO Penny

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. NICKOLOFF Jac

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. Lee Younghyun

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 正岡綾

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 砂田成章

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 平川博一

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. Li Huizi

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. FUJIMORI Hiroaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 益谷美都子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sai Sei 佐井 星

SAI SEI 崔 星

CUI Xing 崔 星

Research Projects

Research Products

Co-Researchers

Basic Research on Gastrointestinal Cancer Stem Cell Targeting Therapy with Heavy Ion BeamsPrincipal Investigator

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Basic research to explore factors to improve effectiveness of radiation therapy

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cDNAマイクロアレイによる新規ヒ素発癌関連遺伝子の同定Principal Investigator

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Determination of genetic susceptibility factors for atmospheric toxic substances.

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[Journal Article] The complexity of DNA double strand break is a crucial factor for activating ATR signaling pathway for G2/M checkpoint regulation regardless of ATM function2015

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[Journal Article] Combination of Carbon Ion Beam and Gemcitabine Causes Unreparable DNA Damage and Death of Radioresistant Pancreatic Cancer Stem-Like Cells In Vitro and In Vivo2015

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[Journal Article] Progesterone generates cancer stem cells through membrane progesterone receptor-triggered signaling in basal-like human mammary cells2015

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[Journal Article] The complexity of DNA double strand break is a crucial factor for activating ATR signaling pathway for G2/M checkpoint regulation regardless of ATM function.2015

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[Journal Article] Arsenite induces premature senescence via p53/p21 pathway as a result of DNA damage in human malignant glioblastoma cells.2014

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[Journal Article] Generation of breast cancer stem cells by steroid hormones in irradiated human mammary cell lines.2013

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[Journal Article] Parg Deficiency Confers Radio-sensitization through Enhanced Cell Death in Mouse ES Cells Exposed to Various Forms of Ionizing Radiation.2013

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[Journal Article] Different effects of carbon ion beams and X-rays on clonogenic survival and DNA repair in human pancreatic cancer stem-like cells.2012

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[Journal Article] Stability of arsenic metabolites, arsenic triglutathione [As(GS)_3] and methylarsenic diglutathione [CH_3As(GS)_2], in rat bile.2005

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[Journal Article] Stability of arsenic metabolites, arsenic triglutathine [As(GS)_3] and methylarsenic diglutathione [CH_3As(GS)_2], in rat bile.2005

Author(s)

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[Journal Article] A new metabolic pathway of arsenite : Arsenic-glutathione complexes are substrates for human arsenic methyltransferase Cyt19.2005

Author(s)

Sai Sei 佐井星

SAI SEI 崔星

CUI Xing 崔星