MATSUSHITA Takashi 松下卓

Researcher Number	20343444
Other IDs
Affiliation (based on the past Project Information) *help	2009: 自治医科大学, 医学部, 助教 2003 – 2006: Jichi Med.Sch., Faculty of Medicine, Research Associate, 医学部, 助手
Review Section/Research Field	Principal Investigator Pediatrics Except Principal Investigator Hematology / Hematology / Biological Sciences
Keywords	Principal Investigator AAV / Gene Therapy / Adeno-associated virus / 血友病A / FVIII / アデノ随伴ウイルス(AAV) / 遺伝子治療 / アデノ随伴ウイルス Except Principal Investigator AAVベクター / Msx1 … More / AAV vector / ITR / Rep / 組織特異性 / 遺伝子治療 / Stem cell / Hematopoietic system / Skeletal muscle / Plasticity / Transdifferentiation / Dedifferentiation / AVVベクター / 幹細胞 / 造血系 / 骨格筋 / 可塑性 / 分化転換 / 脱分化 / adaptor molecule / adenoviral vector / targeted vector integration / protein-supplement gene therapy / tissue specificity / TVI法 / AAVS1領域 / 血清型 / 遺伝子導入 / 免疫反応 / 凝固因子 / エリスロポエチン / アダプター分子 / アデノウイルスベクター / 染色体部位特異的遺伝子組込み / 蛋白質補充遺伝子療法 / 担癌ヌードマウス / ヒストン脱アセチル化酵素阻害剤 / リンパ行性転移抑制 / 抗腫瘍血管遺伝子療法 / VEGF-C / sFlt-4 / sFlt-1 / リンパ管新生 / 血管新生 / バキュロウイルス / がん遺伝子治療 / バイオテクノロジー / 癌 / ウイルス / 遺伝子 Less

Development of AAV (adeno-associated virus) vectors and their application to cancer therapy
- Principal Investigator
  
  OZAWA Keiya
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Jichi Medical University
Development and Improvement of Therapy of Hemophilia A with Adeno-associated virus vectorPrincipal Investigator
- Principal Investigator
  
  MATSUSHITA Takashi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Jichi Medical University
DEDIFFERENTIATION OF NON-HEMATOPOIETIC TISSUE BY GENETIC MANIPULATION AND ITS ACQUISITION OF PLASTICITY AND HEMATOPOIETIC TRANSDIFFERENTIATION
- Principal Investigator
  
  OZAWA Keiya
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  JICHI MEDICAL UNIVERSITY
Development of basic technologies for gene therapy using adeno-associated virus (AAV)
- Principal Investigator
  
  OZAWA Kaiya
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical School

All 2006 2004 Other

All Journal Article

[Journal Article] Suppression of ovarian cancer by muscle-mediated expression of soluble VEGFR-1/Flt-1 using adeno-associated virus serotype 1-derived vector.2006
- Author(s)
  Takei, Y., Mizukami, H., Saga, Y., Yoshimura, I., Hasumi, Y., Takayama, T., Kohno, T., Matsushita, T., Okada, T., Kume, A., Suzuki, M., Ozawa, K.
- Journal Title
  
  Int. J. Cancer 120
  
  Pages: 278-284
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016067
[Journal Article] Utility of intraperitoneal administration as a route of AAV serotype 5 vector-mediated neonatal gene transfer.2006
- Author(s)
  Ogura, T., Mizukami, H., Mimuro, J., Madoiwa, S., Okada, T., Matsushita, T., Urabe, M., Kume, A., Hamada, H., Yoshikawa, H., Sakata, Y., Ozawa, K.
- Journal Title
  
  Gene Med. 8
  
  Pages: 990-997
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016067
[Journal Article] The adenovirus E1A and E1B19K genes provide a helper function for transfection-based adeno-associated virus vector production.2004
- Author(s)
  Matsushita, T.
- Journal Title
  
  J.Gen.Virol. 85・Pt8
  
  Pages: 2209-2214
- NAID
  110006452410
- Data Source
  KAKENHI-PROJECT-16390281
[Journal Article] Separate control of Rep and Cap expression utilizing mutant and wild-type loxP sequences and improved packaging system for adeno-associated virus vector production.2004
- Author(s)
  Mizukami, H., Okada, T., Ogasawara, Y., Matsushita, T., Urabe, M., Kume, A., Ozawa, K.
- Journal Title
  
  Mol.Biotechnol. 27
  
  Pages: 7-14
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390281
[Journal Article] The adenovirus E1A and E1B19K genes provide a helper function for transfection-based adeno-associated virus vector production.2004
- Author(s)
  Matsushita, T.
- Journal Title
  
  J. Gen. Virol. 85・pt8
  
  Pages: 2209-2214
- NAID
  110006452410
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390281
[Journal Article] Adeno-associated virus (AAV) vector-mediated liver- and muscle-directed transgene expression using various kinds of promoters and serotypes.2004
- Author(s)
  Mochizuki, S., Mizukami, H., Kume, A., Muramatsu, S., Takeuchi, K., Matsushita, T., Okada, T., Kobayashi, E., Hoshika, A., Ozawa K.
- Journal Title
  
  Gene Ther.Mol.Biol. 8
  
  Pages: 9-18
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390281
[Journal Article] The adenovirus E1A and E1B19K genes provide a helper function for transfection-based adeno-associated virus vector production.2004
- Author(s)
  Matsushita, T., Okada, T., Inaba, T., Mizukami, H., Ozawa, K., Colosi, P.
- Journal Title
  
  J.Gen.Virol. 85
  
  Pages: 2209-2214
- NAID
  110006452410
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390281
[Journal Article] Adeno-associated virus vector-mediated interleukin-10 gene transfer inhibits atherosclerosis in apolipoprotein E-deficient mice.2004
- Author(s)
  Yoshioka, T., Okada, T., Maeda, Y., Ikeda, U., Shimpo, M., Nomoto, T., Takeuchi, K., Nonaka-Sarukawa, M., Ito, T., Takahashi, M., Matsushita, T., Mizukami, H., Hanazono, Y., Kume, A., Ookawara, S., Kawano, M., Ishibashi, S., Shimada, K., Ozawa, K.
- Journal Title
  
  Gene Ther. 11
  
  Pages: 1772-1779
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390281
[Journal Article] Utility of intraperitoneal administration as a route of AAV serotype 5 vector-mediated neonatal gene transfer.
- Author(s)
  Ogura, T., Mizukami, H., Mimuro, J., Madoiwa, S., Okada, T., Matsushita, T., Urabe, M., Kume, A., Hamada, H., Yoshikawa, H., Sakata, Y., Ozawa, K.
- Journal Title
  
  J.Gene Med. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390281

1. OZAWA Keiya (30137707)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
2. MIZUKAMI Horoaki (20311938)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
3. OKADA Takashi (00326828)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. URABE Masashi (40213516)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. TSUKAHARA Tomonri (10362120)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. KUME Akihiro (10264293)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
7. 岡田尚已

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

MATSUSHITA Takashi 松下 卓

Research Projects

Research Products

Co-Researchers

Development of AAV (adeno-associated virus) vectors and their application to cancer therapy

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development and Improvement of Therapy of Hemophilia A with Adeno-associated virus vectorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

DEDIFFERENTIATION OF NON-HEMATOPOIETIC TISSUE BY GENETIC MANIPULATION AND ITS ACQUISITION OF PLASTICITY AND HEMATOPOIETIC TRANSDIFFERENTIATION

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of basic technologies for gene therapy using adeno-associated virus (AAV)

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Suppression of ovarian cancer by muscle-mediated expression of soluble VEGFR-1/Flt-1 using adeno-associated virus serotype 1-derived vector.2006

Author(s)

Journal Title

Data Source

[Journal Article] Utility of intraperitoneal administration as a route of AAV serotype 5 vector-mediated neonatal gene transfer.2006

Author(s)

Journal Title

Data Source

[Journal Article] The adenovirus E1A and E1B19K genes provide a helper function for transfection-based adeno-associated virus vector production.2004

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Separate control of Rep and Cap expression utilizing mutant and wild-type loxP sequences and improved packaging system for adeno-associated virus vector production.2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] The adenovirus E1A and E1B19K genes provide a helper function for transfection-based adeno-associated virus vector production.2004

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] Adeno-associated virus (AAV) vector-mediated liver- and muscle-directed transgene expression using various kinds of promoters and serotypes.2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] The adenovirus E1A and E1B19K genes provide a helper function for transfection-based adeno-associated virus vector production.2004

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] Adeno-associated virus vector-mediated interleukin-10 gene transfer inhibits atherosclerosis in apolipoprotein E-deficient mice.2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Utility of intraperitoneal administration as a route of AAV serotype 5 vector-mediated neonatal gene transfer.

Author(s)

Journal Title

Description

Data Source

MATSUSHITA Takashi 松下卓