Shinkai Takahiro 新開隆弘

… Alternative Names

新開隆弘シンカイタカヒロ

SHINKAI Takahiro 新開隆弘

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Researcher Number	20352304
Other IDs
Affiliation (Current)	2025: 産業医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2018 – 2020: 産業医科大学, 医学部, 准教授 2008: University of Occupational and Environmental Health, Japan, 医学部, 講師 2007: University of Occupational and Environmental Health, Japan, 医学部, 助教 2006: 産業医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Psychiatric science Except Principal Investigator Basic Section 52030:Psychiatry-related
Keywords	Principal Investigator オーダーメイド医療 / 水中毒 / 遅発性ジスキネジア / 関連研究 / 遺伝子多型 / 統合失調症 Except Principal Investigator 脳由来神経栄養因子 / 病態生理 / MRI / HVA … More / MHPG / コネクトーム / BDNF / IGF-1 / エキソソーム / 脳画像 / 糖尿病 / 脳内ネットワーク / アルギニン一酸化窒素経路 / キヌレニン経路 / 神経画像 / 神経免疫 / 神経炎症 / うつ病 Less

Common Pathophysiology between major depression and diabetes mellitus
- Principal Investigator
  
  YOSHIMURA REIJI
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  University of Occupational and Environmental Health, Japan
Molecular mechanisms of schizophrenia and pharmacogenetics in the treatment of schizophreniaPrincipal Investigator
- Principal Investigator
  
  SHINKAI Takahiro
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  University of Occupational and Environmental Health, Japan

All 2009 2008 2007 2006

All Journal Article Presentation Book

[Book] Tardive Dyskinesia, Molecular Mechanisms. In : Encyclopedia of Molecular Mechanisms of Disease, Florian Lang (Ed.)2009
- Author(s)
  TAKAHIRO SHINKAI
- Publisher
  Springer(in press)
- Data Source
  KAKENHI-PROJECT-18591319
[Journal Article] No association between a functional polymorphism in the promoter region of the neuropeptide Y gene (-485C>T) and schizophrenia.2009
- Author(s)
  Inoue Y, Shinkai T, Utsunomiya K, Sakata S, Fukunaka Y, Yamaguchi W, Yamada K, Chen HI, Hwang R, Ohmori O, Nakamura J.
- Journal Title
  
  Neurosci Lett. 452(1)
  
  Pages: 72-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591319
[Journal Article] Association analysis between the C-1291G polymorphism in the promoter region of the adrenergic α2A receptor gene and polydipsia in schizophrenia.2009
- Author(s)
  Yamaguchi W, Shinkai T, Inoue Y, Utsunomiya K, Sakata S, Fukunaka Y, Yamada K, Chen HI, Hwang R, Ohmori O, Nakamura J.
- Journal Title
  
  Prog Neuropsychopharmacol Biol Psychiatry (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591319
[Journal Article] Functional polymorphism of the human multidrug resistance gene (MDR1) and polydipsia-hyponatremia in schizophrenia.2008
- Author(s)
  Shinkai, et al.
- Journal Title
  
  NeuroMolecular Medicine 10
  
  Pages: 362-367
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591319
[Journal Article] Genetic association between the dopamine D3 gene polymorphism (Ser9Gly) and schizophrenia in Japanese populations : evidence from a case-control study and meta-analysis.2008
- Author(s)
  Utsunomiya K, Shinkai T, De Luca V, Hwang R, Sakata S, Fukunaka Y, Chen HI, Ohmori O, Nakamura J.
- Journal Title
  
  Neurosci Lett. 444(2)
  
  Pages: 161-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591319
[Journal Article] Functional polymorphism of the human multidrug resistance gene (MDR1) and polydipsia-hyponatremia in schizophrenia2008
- Author(s)
  Shinkai T, De Luca V, Utsunomiya K, Sakata S, Inoue Y, Fukunaka Y, Hwang R, Ohmori O, Kennedy JL, Nakamura J.
- Journal Title
  
  Neuromolecular Med. 10(4)
  
  Pages: 362-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591319
[Journal Article] Association analyses of the DAOA/G30 and D-amino-acid oxidase genes in schizophrenia:further evidence for a role in schizophrenia2007
- Author(s)
  T.Shinkai, et. al.
- Journal Title
  
  NeuroMolecular Medicine 9(2)
  
  Pages: 169-178
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591319
[Journal Article] Association study of four dopamine D1 receptor gene polymorphisms and clozapine treatment response.2007
- Author(s)
  Hwang R, Shinkai T, De Luca V, Ni X, Potkin SG, Lieberman JA, Meltzer HY, Kennedy JL.
- Journal Title
  
  J Psychopharmacol. 21(7)
  
  Pages: 718-27
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591319
[Journal Article] 抗精神病薬による水中毒をどう予測するか2007
- Author(s)
  新開隆弘, 他
- Journal Title
  
  臨床精神薬理 10(8)
  
  Pages: 1423-1431
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591319
[Journal Article] The orexin 1 receptor (HCRTR1) gene as a susceptibility gene contributing to polydipsia-hyponatremia in schizophrenia.2007
- Author(s)
  Fukunaka Y, Shinkai T, Hwang R, Hori H, Utsunomiya K, Sakata S, Naoe Y, Shimizu K, Matsumoto C, Ohmori O, Nakamura J.
- Journal Title
  
  Neuromolecular Med. 9(4)
  
  Pages: 292-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591319
[Journal Article] G72とD-アミノ酸酸化酵素(DAAO)2007
- Author(s)
  新開隆弘
- Journal Title
  
  Schizophrenia Frontier 8(3)
  
  Pages: 34-41
- Data Source
  KAKENHI-PROJECT-18591319
[Journal Article] Association analyses of the DAOA/G30 and D-amino-acid oxidase genes in schizophrenia : further evidence for a role in schizophrenia.2007
- Author(s)
  Shinkai T, De Luca V, Hwang R, Muller DJ, Lanktree M, Zai G, Shaikh S, Wong G, Sicard T, Potapova N, Trakalo J, King N, Matsumoto C, Hori H, Wong AH, Ohmori O, Macciardi F, Nakamura J, Kennedy JL.
- Journal Title
  
  Neuromolecular Med. 9(2)
  
  Pages: 169-77
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591319
[Journal Article] No association between the brain-derived neurotrophic factor (BDNF) Val66Met polymorphism and schizophrenia in Asian populations : Evidence from a case-control study and meta-analysis.2007
- Author(s)
  Naoe Y, Shinkai T, Hori H, Fukunaka Y, Utsunomiya K, Sakata S, Matsumoto C, Shimizu K, Hwang R, Ohmori O, Nakamura J.
- Journal Title
  
  Neurosci Lett. 415(2)
  
  Pages: 108-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591319
[Journal Article] No association between a functional NAD(P)H : quinone oxidoreductase gene polymorphism (Pro187Ser) and tardive dyskinesia.2006
- Author(s)
  Hori H, Shinkai T, Matsumoto C, Ohmori O, Nakamura J.
- Journal Title
  
  Neuromolecular Med. 8(3)
  
  Pages: 375-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591319
[Journal Article] Genetic association analysis of the glutathione peroxidase (GPX1) gene polymorphism (Pro197Leu) with tardive dyskinesia.2006
- Author(s)
  Shinkai T, Muller DJ, De Luca V, Shaikh S, Matsumoto C, Hwang R, King N, Trakalo J, Potapova N, Zai G, Hori H, Ohmori O, Meltzer HY, Nakamura J, Kennedy JL.
- Journal Title
  
  Psychiatry Res. 141(2)
  
  Pages: 123-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591319
[Journal Article] Association study between functional polymorphisms in the cytochrome P450 1A2 and 2D6 genes and polydipsia in schizophrenia.2006
- Author(s)
  Matsumoto C, Shinkai T, De Luca V, Hori H, Hwang R, Ohmori O, Kennedy JL, Nakamura J.
- Journal Title
  
  Neuromolecular Med. 8(3)
  
  Pages: 381-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591319
[Journal Article] Genetic association analysis of the glutathione peroxidase (GPX1) gene polymorphism (Pro197Leu) with tardive dyskinesia.2006
- Author(s)
  Shinkai T, Matsumoto C, Shaikh S, De Luca V, Muller DJ, Hwang R, King N, Trakalo J, Potapova N, Hori H, Ohmori O, Meltzer HY, Nakamura J, Kennedy JL
- Journal Title
  
  Psychiatry Res. 141(2)
  
  Pages: 123-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591319
[Journal Article] Genetic association analysis of the glutathione peroxidase (GPX1) gene polymorphism (Pro197Leu) with tardive dyskinesia.2006
- Author(s)
  T.Shinkai, et al.
- Journal Title
  
  Psychiatry Research 141(2)
  
  Pages: 123-128
- Data Source
  KAKENHI-PROJECT-18591319
[Journal Article] Dopamine D2 receptor gene variants and quantitative measures of positive and negative symptom response following clozapine treatment.2006
- Author(s)
  Hwang R, Shinkai T, Deluca V, Macciardi F, Potkin S, Meltzer HY, Kennedy JL.
- Journal Title
  
  Eur Neuropsychopharmacol. 16(4)
  
  Pages: 248-59
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591319
[Presentation] Ethnic difference in pharmacogenetics of serious adverse effects of antipsychotics : tardive dyskinesia and more2008
- Author(s)
  Shinkai, et al.
- Organizer
  16^<th> World Congress on Psychiatric Genetics
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-18591319
[Presentation] Association between the leptin receptor gene (LEPR) polymorphism (Gln223Arg) and late-onset Alzheimer's disease.2008
- Author(s)
  Kensuke Utsunomiya, Takahiro Shinkai, Shinichi Sakata, Yoshiaki Inoue, Yuko Fukunaka, Wakana Yamaguchi, Kenji Yamada, Osamu Ohmori, Jun Nakamura.
- Organizer
  XVIth World Congress on Psychiatric Genetics
- Place of Presentation
  Osaka
- Data Source
  KAKENHI-PROJECT-18591319
[Presentation] NMDA受容体遺伝子(GRIN2B)と統合失調症における病的多飲2008
- Author(s)
  Shinkai, et al.
- Organizer
  第18回日本臨床精神神経薬理学会第38回日本神経精神薬理学会合同年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-18591319
[Presentation] Ethnic differences in pharmacogenetics of serious adverse effects of antipsychotics : tardive dyskinesia and more.2008
- Author(s)
  Takahiro Shinkai, Hiroko Hori, Kensuke Utsunomiya, Chima Matsumoto, Shinichi Sakata, Yoshiaki Inoue, Yuko Fukunaka, Wakana Yamaguchi, Hsin-I Chen, Rudi Hwang, Vincenzo De Luca Daniel J. Muller, Osamu Ohmori, James L. Kennedy, Jun Nakamura.
- Organizer
  XVIth World Congress on Psychiatric Genetics
- Place of Presentation
  Osaka
- Data Source
  KAKENHI-PROJECT-18591319
[Presentation] NMDA型グルタミン酸受容体2B(GRIN2B)遺伝子多型と統合失調症における病的多飲2008
- Author(s)
  新開隆弘, 他
- Organizer
  2^<nd> WFSBP Asia-Pacific Congress and 30^<th> Annual Meeting of JSBP
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-18591319
[Presentation] Association study between the NMDA receptor subunit 2B (GRIN2B) gene and polydipsia in schizophrenia.2008
- Author(s)
  Takahiro Shinkai, Shinichi Sakata, Hiroko Yamamoto, Kensuke Utsunomiya, Yuko Fukunaka, Yoshiaki Inoue, Wakana Yamaguchi, Kenji Yamada, Hsin-I Chen, Osamu Ohmori, Jun Nakamura.
- Organizer
  XVIth World Congress on Psychiatric Genetics
- Place of Presentation
  Osaka
- Data Source
  KAKENHI-PROJECT-18591319
[Presentation] Association between the NMDA receptor subunit 2B (GRIN2B) gene and polydipsia in schizophrenia2008
- Author(s)
  Shinkai, et al.
- Organizer
  16^<th> World Congress on Psychiatric Genetics
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-18591319
[Presentation] Genetic association analysis between the NMDA receptor subunit 2B gene and schizophrenia.2008
- Author(s)
  Shinichi Sakata, Takahiro Shinkai, Hiroko Yamamoto, Kensuke Utsunomiya, Yoshiaki Inoue, Yuko Fukunaka, Wakana Yamaguchi, Kenji Yamada, Kazuko Shimizu, Hsin-I Chen, Osamu Ohmori, Jun Nakamura.
- Organizer
  XVIth World Congress on Psychiatric Genetics
- Place of Presentation
  Osaka
- Data Source
  KAKENHI-PROJECT-18591319
[Presentation] Association study between the DNA repair gene XRCC1 and schizophrenia.2008
- Author(s)
  Kenji Yamada, Takahiro Shinkai, Shinichi Sakata, Kensuke Utsunomiya, Yuko Fukunaka, Osamu Ohmori, Jun Nakamura.
- Organizer
  XVIth World Congress on Psychiatric Genetics
- Place of Presentation
  Osaka
- Data Source
  KAKENHI-PROJECT-18591319
[Presentation] Genetic association analysis between the NPR-1 gene polymorphism (M341I) and polydipsia in schizophrenia.2008
- Author(s)
  Yuko Fukunaka , Takahiro Shinkai, Hsin-I Chen , Kensuke Utsunomiya ,Shinichi Sakata, Osamu Ohmori, Jun Nakamura.
- Organizer
  XVIth World Congress on Psychiatric Genetics
- Place of Presentation
  Osaka
- Data Source
  KAKENHI-PROJECT-18591319
[Presentation] TPH2 polymorphisms and polydipsia in schizophrenia2007
- Author(s)
  T.Shinkai, et. al.
- Organizer
  XV World Congress on Psychigtric Genetics
- Place of Presentation
  New York,USA
- Data Source
  KAKENHI-PROJECT-18591319
[Presentation] TPH2遺伝子多型と統合失調症における病的多飲2007
- Author(s)
  新開隆弘, 他
- Organizer
  第17回日本臨床精神神経薬理学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-18591319
[Presentation] Genetics of polydipsia in schizophrenia2007
- Author(s)
  T.Shinkai, et. al.
- Organizer
  XV World Congress on Psychiatric Genetics
- Place of Presentation
  New York,USA
- Data Source
  KAKENHI-PROJECT-18591319

1. NAKAMUARA Jun (40148804)

# of Collaborated Projects: 2 results

# of Collaborated Products: 17 results
2. SAKATA Shinichi (80425313)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
3. HORI Hiroko (80412641)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
4. OHMORI Osamu (70248558)

# of Collaborated Projects: 1 results

# of Collaborated Products: 17 results
5. MATSUMOTO Chima (80421329)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
6. NAOE Yui (10421330)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. UTSUNOMIYA Kensuke (90425314)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
8. FUKUNAKA Yuko (60441854)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
9. INOUE Yoshiaki (10461550)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
10. YAMAGUCHI Wakana (20461551)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
11. YOSHIMURA REIJI (90248568)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 原田大 (00241175)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 井形亮平 (00739477)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 手銭宏文 (00790982)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 掛田伸吾 (30352313)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 本間雄一 (30620984)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 興梠征典 (60195691)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 小西勇輝 (90739476)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 星川大 (20842181)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Shinkai Takahiro 新開 隆弘

新開 隆弘 シンカイ タカヒロ

SHINKAI Takahiro 新開 隆弘

Research Projects

Research Products

Co-Researchers

Common Pathophysiology between major depression and diabetes mellitus

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanisms of schizophrenia and pharmacogenetics in the treatment of schizophreniaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Tardive Dyskinesia, Molecular Mechanisms. In : Encyclopedia of Molecular Mechanisms of Disease, Florian Lang (Ed.)2009

Author(s)

Publisher

Data Source

[Journal Article] No association between a functional polymorphism in the promoter region of the neuropeptide Y gene (-485C>T) and schizophrenia.2009

Author(s)

Journal Title

Data Source

[Journal Article] Association analysis between the C-1291G polymorphism in the promoter region of the adrenergic α2A receptor gene and polydipsia in schizophrenia.2009

Author(s)

Journal Title

Data Source

[Journal Article] Functional polymorphism of the human multidrug resistance gene (MDR1) and polydipsia-hyponatremia in schizophrenia.2008

Author(s)

Journal Title

Data Source

[Journal Article] Genetic association between the dopamine D3 gene polymorphism (Ser9Gly) and schizophrenia in Japanese populations : evidence from a case-control study and meta-analysis.2008

Author(s)

Journal Title

Data Source

[Journal Article] Functional polymorphism of the human multidrug resistance gene (MDR1) and polydipsia-hyponatremia in schizophrenia2008

Author(s)

Journal Title

Data Source

[Journal Article] Association analyses of the DAOA/G30 and D-amino-acid oxidase genes in schizophrenia:further evidence for a role in schizophrenia2007

Author(s)

Journal Title

Data Source

[Journal Article] Association study of four dopamine D1 receptor gene polymorphisms and clozapine treatment response.2007

Author(s)

Journal Title

Data Source

[Journal Article] 抗精神病薬による水中毒をどう予測するか2007

Author(s)

Journal Title

Data Source

[Journal Article] The orexin 1 receptor (HCRTR1) gene as a susceptibility gene contributing to polydipsia-hyponatremia in schizophrenia.2007

Author(s)

Journal Title

Data Source

[Journal Article] G72とD-アミノ酸酸化酵素(DAAO)2007

Author(s)

Journal Title

Data Source

[Journal Article] Association analyses of the DAOA/G30 and D-amino-acid oxidase genes in schizophrenia : further evidence for a role in schizophrenia.2007

Author(s)

Journal Title

Data Source

[Journal Article] No association between the brain-derived neurotrophic factor (BDNF) Val66Met polymorphism and schizophrenia in Asian populations : Evidence from a case-control study and meta-analysis.2007

Author(s)

Journal Title

Data Source

[Journal Article] No association between a functional NAD(P)H : quinone oxidoreductase gene polymorphism (Pro187Ser) and tardive dyskinesia.2006

Author(s)

Journal Title

Data Source

[Journal Article] Genetic association analysis of the glutathione peroxidase (GPX1) gene polymorphism (Pro197Leu) with tardive dyskinesia.2006

Author(s)

Journal Title

Data Source

[Journal Article] Association study between functional polymorphisms in the cytochrome P450 1A2 and 2D6 genes and polydipsia in schizophrenia.2006

Author(s)

Shinkai Takahiro 新開隆弘

新開隆弘シンカイタカヒロ

SHINKAI Takahiro 新開隆弘