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ENDO Hiroko  遠藤 洋子

ORCIDConnect your ORCID iD *help
Researcher Number 20359300
Affiliation (based on the past Project Information) *help 2018 – 2019: 地方独立行政法人大阪府立病院機構大阪国際がんセンター(研究所), その他部局等, 主任研究員
2017: 地方独立行政法人大阪府立病院機構大阪国際がんセンター(研究所), 研究所, 主任研究員
2016: 地方独立行政法人大阪府立病院機構大阪国際がんセンター(研究所), 研究所, 研究員
2014 – 2015: 地方独立行政法人大阪府立病院機構大阪府立成人病センター(研究所), 研究所, 研究員
2014: 地方独立行政法人大阪府立病院機構大阪府立成人病センター(研究所), その他部局等, その他 … More
2013: 地方独立行政法人大阪府立病院機構大阪府立成人病センター(研究所), 研究所 生化学部門, 研究員
2012 – 2013: 地方独立行政法人大阪府立病院機構大阪府立成人病センター(研究所), その他部局等, 研究員
2012: 大阪府立成人病センター(研究所), 研究所, 研究員
2011 – 2012: 地方独立行政法人大阪府立病院機構大阪府立成人病センター(研究所), 研究所, 研究員
2010 – 2011: 地方独立行政法人 大阪府立病院機構 大阪府立成人病センター(研究所), 研究所, 研究員
2009 – 2010: 地方独立行政法人大阪府立病院機構大阪府立成人病センター(研究所), 研究員
2008: Research Institute, Osaka Medical Center for Cancer and Cardiovascular Disaeses, 大阪府立成人病センター(研究所)・研究所, 研究員
2008: 地方独立行政法人大阪府立病院機構, 大阪府立成人病センター研究所, 研究員
2008: 地方独立行政法人大阪府立病院機構大阪府立成人病センター, 研究所, 研究員
2007 – 2008: 地方独立行政法人大阪府立病院機構大阪府立成人病センター(研究所), 研究所, 研究員
2007: Research Institute, Osaka Medical Center for Cancer and Cardiovascular Disaeses, 研究所, 研究員 Less
Review Section/Research Field
Principal Investigator
Radiation science / Basic Section 52040:Radiological sciences-related
Except Principal Investigator
Tumor biology / Experimental pathology / Pathological medical chemistry
Keywords
Principal Investigator
放射線感受性 / 大腸癌 / 癌細胞初代培養 / 放射線腫瘍学 / 三次元培養系 / 分化型腺癌 / 分化 / 低酸素 / 休眠状態 / 放射線感受性試験 / 放射線治療 / オートファジー / 小胞体ストレス … More
Except Principal Investigator
… More ERBBシグナル / WNTシグナル / 幹細胞性 / 再生 / 破壊 / 培養 / 癌 / HIF / VEGF / 浸潤 / 血管新生 / 細胞死 / 低酸素 / mTOR / PI3K / IGF / 分子腫瘍学 Less
  • Research Projects

    (8 results)
  • Research Products

    (68 results)
  • Co-Researchers

    (7 People)
  •  細胞間相互作用がもたらす幹細胞/ニッチ微小環境による放射線耐性メカニズムの検討Principal Investigator

    • Principal Investigator
      遠藤 洋子
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      Osaka International Cancer Institute
  •  Investigation of radio-resistant mechanism of well differentiated adenocarcinoma using a primary culture system, CTOSPrincipal Investigator

    • Principal Investigator
      Endo Hiroko
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      Osaka International Cancer Institute
  •  Radiation sensitivity in dormant tumor cells using a novel primary culture systemPrincipal Investigator

    • Principal Investigator
      Endo Hiroko
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      Research Institute, Osaka Medical Center for Cancer and Cardiovascular Disaeses
  •  Malignant conversion of cancer cells by disruption and remodeling of cancer cell-clusters in newly developed primary culture system

    • Principal Investigator
      INOUE Masahiro
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Tumor biology
    • Research Institution
      Research Institute, Osaka Medical Center for Cancer and Cardiovascular Disaeses
  •  Establishment of radio sensitivity assay with a novel primary culture system from cancer patientsPrincipal Investigator

    • Principal Investigator
      ENDO Hiroko
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Radiation science
    • Research Institution
      Research Institute, Osaka Medical Center for Cancer and Cardiovascular Disaeses
  •  Mechanism of inducing invasive phenotype after VEGF inhibition

    • Principal Investigator
      INOUE Masahiro
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Research Institute, Osaka Medical Center for Cancer and Cardiovascular Disaeses
  •  Hypoxia resistance of cancer cells by suppressing IGF/PI3K/mTOR

    • Principal Investigator
      INOUE Masahiro
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Research Institute, Osaka Medical Center for Cancer and Cardiovascular Disaeses
  •  Increased radiosensitivity through autophagyPrincipal Investigator

    • Principal Investigator
      ENDO Hiroko
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Radiation science
    • Research Institution
      Research Institute, Osaka Medical Center for Cancer and Cardiovascular Disaeses

All 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2008 2007 Other

All Journal Article Presentation

  • [Journal Article] Dormancy in cancer2019

    • Author(s)
      Endo Hiroko、Inoue Masahiro
    • Journal Title

      Cancer Science

      Volume: 110 Issue: 2 Pages: 474-480

    • DOI

      10.1111/cas.13917

    • NAID

      120006557516

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-26111005, KAKENHI-PROJECT-16K10414
  • [Journal Article] Promotion of malignant phenotype after disruption of the three-dimensional structure of cultured spheroids from colorectal cancer.2018

    • Author(s)
      Piulats JM, Kondo J, Endo H, Ono H, Hagihara T, Okuyama H, Nishizawa Y, Tomita Y, Ohue M, Okita K, Oyama H, Bono H, Masuko T, Inoue M.
    • Journal Title

      Oncotarget

      Volume: 9 Issue: 22 Pages: 15968-15983

    • DOI

      10.18632/oncotarget.24641

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08391, KAKENHI-PROJECT-16K10414
  • [Journal Article] High-throughput screening in colorectal cancer tissue-originated spheroids2018

    • Author(s)
      Kondo Jumpei、Ekawa Tomoya、Endo Hiroko、Yamazaki Kanami、Tanaka Norio、Kukita Yoji、Okuyama Hiroaki、Okami Jiro、Imamura Fumio、Ohue Masayuki、Kato Kikuya、Nomura Taisei、Kohara Arihiro、Mori Seiichi、Dan Shingo、Inoue Masahiro
    • Journal Title

      Cancer Science

      Volume: 110 Issue: 1 Pages: 345-355

    • DOI

      10.1111/cas.13843

    • NAID

      120006547404

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07926, KAKENHI-PLANNED-26111005, KAKENHI-PROJECT-17H01623, KAKENHI-PROJECT-18H02648, KAKENHI-PROJECT-16K10414
  • [Journal Article] Spheroid Cultures of Primary Urothelial Cancer Cells: Cancer Tissue-Originated Spheroid (CTOS) Method.2018

    • Author(s)
      Yoshida T, Okuyama H, Endo H, Inoue M.
    • Journal Title

      Methods Mol Biol.

      Volume: 1655 Pages: 145-153

    • DOI

      10.1007/978-1-4939-7234-0_12

    • ISBN
      9781493972333, 9781493972340
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K10414, KAKENHI-PLANNED-26111005
  • [Journal Article] In vivo and ex vivo cetuximab sensitivity assay using three-dimensional primary culture system to stratify KRAS mutant colorectal cancer2017

    • Author(s)
      Tashiro T, Okuyama H, Endo H, Kawada K, Ashida Y, Ohue M, Sakai Y, Inoue M.
    • Journal Title

      PLoS One

      Volume: 12 Issue: 3 Pages: e0174151-e0174151

    • DOI

      10.1371/journal.pone.0174151

    • NAID

      120006539603

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-26111005, KAKENHI-PROJECT-16K10414
  • [Journal Article] The distinct metabolic phenotype of lung squamous cell carcinoma defines selective vulnerability to glycolytic inhibition.2017

    • Author(s)
      Goodwin J, Neugent ML, Lee SY, Choe JH, Choi H, Jenkins DMR, Ruthenborg RJ, Robinson MW, Jeong JY, Wake M, Abe H, Takeda N, Endo H, Inoue M, Xuan Z, Yoo H, Chen M, Ahn JM, Minna JD, Helke KL, Singh PK, Shackelford DB, Kim JW.
    • Journal Title

      Nature Communications

      Volume: 8 Issue: 1 Pages: 15503-15503

    • DOI

      10.1038/ncomms15503

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10414, KAKENHI-INTERNATIONAL-15K21759, KAKENHI-PLANNED-26111003, KAKENHI-PLANNED-26111005
  • [Journal Article] Furospinosulin-1, marine spongean furanosesterterpene, suppresses the growth of hypoxia-adapted cancer cells by binding to transcriptional regulators p54nrb and LEDGF/p75.2016

    • Author(s)
      Arai, M.; Kawachi, T.; Kotoku, N.; Nakata, C.; Kamada, H.; Tsunoda, S.; Tsutsumi, Y.; Endo, H.; Inoue, M.; Sato, H.; Kobayashi, M.
    • Journal Title

      ChemBioChem

      Volume: 17 Issue: 2 Pages: 181-189

    • DOI

      10.1002/cbic.201500519

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-23102005, KAKENHI-PLANNED-26111005, KAKENHI-PROJECT-25461937, KAKENHI-PROJECT-26242074, KAKENHI-PROJECT-26305002
  • [Journal Article] The induction of MIG6 under hypoxic conditions is critical for dormancy in primary cultured lung cancer cells with activating EGFR mutations2016

    • Author(s)
      Endo H, Okami J, Okuyama H, Nishizawa Y, Imamura F, Inoue M
    • Journal Title

      Oncogene

      Volume: epub ahead of print Issue: 20 Pages: 2824-2834

    • DOI

      10.1038/onc.2016.431

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-26111005, KAKENHI-PROJECT-16K10414
  • [Journal Article] A limited overlap between intratumoral distribution of 1-(5-fluoro-5-deoxy-alpha-D-arabinofuranosyl)-2-nitroimidazole and copper-diacetyl-bis[N(4)-methylthiosemicarbazone]2015

    • Author(s)
      Furukawa T, Yuan Q, Jin ZH, Aung W, Yoshii Y, Hasegawa S, Endo H, Inoue M, Zhang MR, Fujibayashi Y, Saga T.
    • Journal Title

      Oncol Rep.

      Volume: 34 Issue: 3 Pages: 1379-1387

    • DOI

      10.3892/or.2015.4079

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-26111005, KAKENHI-PROJECT-25461937
  • [Journal Article] Analysis of ERBB ligand-induced resistance mechanism to crizotinib by primary culture of lung adenocarcinoma with EML4-ALK fusion gene.2015

    • Author(s)
      Kimura M, Endo H, Inoue T, Nishino K, Uchida J, Kumagai T, Kukita Y, Kato K, Imamura F, Inoue M
    • Journal Title

      Journal of Thoracic Oncology

      Volume: 10 Issue: 3 Pages: 527-30

    • DOI

      10.1097/jto.0000000000000381

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25461937
  • [Journal Article] Immuno-PET Imaging of HER3 in a Model in which HER3 Signaling Plays a Critical Role2015

    • Author(s)
      Yuan Q, Furukawa T, Tashiro T, Okita K, Jin ZH, Aung W, Sugyo A, Nagatsu K, Endo H, Tsuji AB, Zhang MR, Masuko T, Inoue M, Fujibayashi Y, Saga T.
    • Journal Title

      PloS one

      Volume: 10 Issue: 11 Pages: e0143076-e0143076

    • DOI

      10.1371/journal.pone.0143076

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-26111005, KAKENHI-PROJECT-25461937
  • [Journal Article] Dynamic Change in p63 Protein Expression during Implantation of Urothelial Cancer Clusters.2015

    • Author(s)
      Yoshida T, Okuyama H, Nakayama M, Endo H, Tomita Y, Nonomura N, Nishimura K, Inoue M.
    • Journal Title

      Neoplasia

      Volume: 17 Issue: 7 Pages: 574-585

    • DOI

      10.1016/j.neo.2015.07.004

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08391, KAKENHI-PLANNED-26111005, KAKENHI-PROJECT-25461937, KAKENHI-PROJECT-26861268
  • [Journal Article] High-dose chemotherapeutics of intravesical chemotherapy rapidly induce mitochondrial dysfunction in bladder cancer-derived spheroids.2015

    • Author(s)
      Yoshida T, Okuyama H, Nakayama M, Endo H, Nonomura N, Nishimura K, Inoue M
    • Journal Title

      Cancer science

      Volume: 106 Issue: 1 Pages: 69-77

    • DOI

      10.1111/cas.12567

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24300333, KAKENHI-PLANNED-26111005
  • [Journal Article] Dormancy of Cancer Cells with Suppression of AKT Activity Contributes to Survival in Chronic Hypoxia.2014

    • Author(s)
      Endo H, Okuyama H, Ohue M, Inoue M
    • Journal Title

      PloS one

      Volume: 9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24300333
  • [Journal Article] Radiation sensitivity assay with a panel of patient-derived spheroids of small cell carcinoma of the cervix.2014

    • Author(s)
      Nakajima A, Endo H, Okuyama H, Kiyohara Y, Kimura T, Kamiura S, Hiraoka M, Inoue M.
    • Journal Title

      Int J Cancer

      Volume: - Issue: 12 Pages: 2949-2960

    • DOI

      10.1002/ijc.29349

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24300333, KAKENHI-PROJECT-25461937, KAKENHI-PLANNED-26111005
  • [Journal Article] Dormancy of cancer cells with suppression of AKT activity contributes to survival in chronic hypoxia2014

    • Author(s)
      Endo H, Okuyama H, Ohue M, Inoue M
    • Journal Title

      PLoS ONE

      Volume: 9 Issue: 6 Pages: e98858-e98858

    • DOI

      10.1371/journal.pone.0098858

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25461937
  • [Journal Article] Spheroid culture of primary lung cancer cells with neuregulin 1/HER3 pathway activation2013

    • Author(s)
      Endo H, Okami J, Okuyama H, Kumagai T, Uchida J, Kondo J, Takehara T, Nishizawa Y, Imamura F, Higashiyama M, Inoue M
    • Journal Title

      J Thorac Oncol

      Volume: 8 Pages: 131-139

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24300333
  • [Journal Article] Involvement of Heregulin/HER3 in the Primary Culture of Human Urothelial Cancer2013

    • Author(s)
      Hiroaki Okuyama
    • Journal Title

      Journal of Urology

      Volume: Epub ahead of print Issue: 1 Pages: 302-310

    • DOI

      10.1016/j.juro.2012.12.106

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22791240, KAKENHI-PROJECT-23501282, KAKENHI-PROJECT-24300333
  • [Journal Article] Involvement of heregulin/HER3 in the primary culture of human urothelial cancer2013

    • Author(s)
      Okuyama H, Yoshida T, Endo H, Nakayama M,Nonomura N, Nishimura K, and Inoue M
    • Journal Title

      J.Urol

      Volume: (Epub ahead of print)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22791240
  • [Journal Article] Spheroid Culture of Primary Lung Cancer Cells with Neuregulin 1/HER3 Pathway Activation2013

    • Author(s)
      Hiroko Endo
    • Journal Title

      Journal of Thoracic Oncology

      Volume: 8 Issue: 2 Pages: 131-139

    • DOI

      10.1097/jto.0b013e3182779ccf

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22791240
  • [Journal Article] Spheroid Culture of Primary Lung Cancer Cells with Neuregulin 1/HER3 Pathway Activation2013

    • Author(s)
      Endo H, Okami J, Okuyama H, Kumagai T, Harada J, Kondo J, Takehara T, Nishizawa Y, Imamura F, Higashiyama M, and Inoue M
    • Journal Title

      Joumal of Thoracic Oncology

      Volume: 2 Pages: 131-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22791240
  • [Journal Article] Retaining cell-cell contact enables preparation and culture of spheroids composed of pure primary cancer cells from COlOreCtal CanCer2011

    • Author(s)
      Kondo J, Endo H, Okuyama H, Ishikawa O, Iishi H, Tsujii M, Ohue M, and Inoue M
    • Journal Title

      Proc Natl Acad Sci USA

      Volume: 108 Issue: 15 Pages: 6235-40

    • DOI

      10.1073/pnas.1015938108

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22791240
  • [Journal Article] Cellular hypoxia of pancreatic β-cells due to high levels of oxygen consumption for insulin secretion in vitro2011

    • Author(s)
      Sato Y., et al
    • Journal Title

      J Biol.Chem.

      Volume: 286 Issue: 14 Pages: 12524-12532

    • DOI

      10.1074/jbc.m110.194738

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21220010, KAKENHI-PROJECT-21590459, KAKENHI-PROJECT-21591184
  • [Journal Article] IGFBPs contribute to survival of pancreatic cancer cells under severely hypoxic conditions2008

    • Author(s)
      Koga, T., Endo, H., Miyamoto, Y., Mukai, M., Akira, S., Inoue, M.
    • Journal Title

      Cancer Lett 68

      Pages: 62-88

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590329
  • [Journal Article] Insulin-like growth factor stimulation increases radiosensitivity of a pancreatic cancer cell line through ER stress under hypoxic conditions2008

    • Author(s)
      Isohashi, F., Endo, H., Mukai, M., et al.
    • Journal Title

      Cancer Sci 99

      Pages: 2395-401

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590329
  • [Journal Article] IGFBPs contribute to survival of pancreatic cancer cells under hypoxic conditions.2008

    • Author(s)
      Koga T, Endo H, Miyamoto Y, Mukai M, Akira S, Inoue M
    • Journal Title

      Cancer Lett 268

      Pages: 82-88

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790910
  • [Journal Article] Insulin-like growth factor stimulation increases radiosensitivity of a pancreatic cancer cell line through ER stress under hypoxic conditions2008

    • Author(s)
      Isohashi, F., Endo, H., Mukai, M., et al.
    • Journal Title

      Cancer Sci 99

      Pages: 2395-401

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790910
  • [Journal Article] IGFBPs contribute to survival of pancreatic cancer cells under severely hypoxic conditions2008

    • Author(s)
      Koga, T., Endo, H., Miyamoto, Y., et al.
    • Journal Title

      Cancer Lett 268

      Pages: 82-88

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590329
  • [Journal Article] IGFBPs contribute to survival of pancreatic cancer cells under severely hypoxic conditions2008

    • Author(s)
      Koga, T., Endo, H., Miyamoto, Y., et al.
    • Journal Title

      Cancer Lett 268

      Pages: 82-88

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790910
  • [Journal Article] Insulin-like growth factor stimulation increases radiosensitivity of a pancreatic cancer cell line through ER stress under hypoxic conditions.2008

    • Author(s)
      Isohasi F, Endo H, Mukai M, Inoue T, Inoue M
    • Journal Title

      Cancer Sci 99

      Pages: 2395-2401

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790910
  • [Journal Article] Insulin-like growth factor stimulation increases radiosensitivity of a pancreatic cancer cell line through ER stress under hypoxic conditions2008

    • Author(s)
      Isohashi, F., Endo, H., Mukai, M., Inoue, T., Inoue, M.
    • Journal Title

      Cancer Sci 99

      Pages: 2395-2401

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590329
  • [Journal Article] Regulation of hypoxia-inducible factor 1 by glucose availability under hypoxic conditions2007

    • Author(s)
      Zhou, J., Hara, K., Inoue, M., Hamada, S., Yasuda, H., Moriyama, H., Endo, H., et al.
    • Journal Title

      Kobe J Med Sci 53

      Pages: 283-296

    • NAID

      110006646896

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590329
  • [Journal Article] Activation of insulin-like growth factor signaling induces apoptotic cell death under prolonged hypoxia by enhancing endoplasmic reticulum stress response2007

    • Author(s)
      Endo, H., Murata, K., Mukai, M., Ishikawa, O., Inoue, M.
    • Journal Title

      Cancer Res 67

      Pages: 8095-8103

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590329
  • [Journal Article] Activation of insulin-like growth factor signaling inducesapoptotic cell death under prolonged hypoxia by enhancing endoplasmic reticulum stress response2007

    • Author(s)
      Endo, H., Murata, K., Mukai, M., et. al.
    • Journal Title

      Cancer Res 67

      Pages: 8095-103

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790910
  • [Journal Article] Activation of insulin-like growth factor signaling induces apoptotic cell death under prolonged hypoxia by enhancing endoplasmic reticulum stress response.2007

    • Author(s)
      Endo H, Murata K, Mukai M, Ishikawa O, Inoue M
    • Journal Title

      Cancer Res 67

      Pages: 8095-8103

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790910
  • [Journal Article] Activation of insulin-like growth factor signaling induces apoptotic cell death under prolonged hypoxia by enhancing endoplasmic reticulum stress response2007

    • Author(s)
      Endo, H., Murata, K., Mukai, M., et. al.
    • Journal Title

      Cancer Res 67

      Pages: 8095-103

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590329
  • [Presentation] HDAC inhibitors sensitize well-differentiated colorectal cancer spheroid to X-ray irradiation2018

    • Author(s)
      Hiroko Endo, Jumpei Kondo, and Masahiro Inoue
    • Organizer
      第77回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-16K10414
  • [Presentation] Induction of dormancy as a survival strategy of cancer cells2018

    • Author(s)
      Hiroko Endo and Masahiro Inoue
    • Organizer
      第41回日本分子生物学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K10414
  • [Presentation] Radiation sensitivity assay for well-differentiated adenocarcinoma using colorectal cancer spheroid2017

    • Author(s)
      Endo H, Kondo J, Inoue M
    • Organizer
      第75回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-16K10414
  • [Presentation] A shuttle system between patient-derived xenograft and ex vivo culture for efficient drug screening.2016

    • Author(s)
      Hiroko Endo, Hiroaki Okuyama, Satoshi Kubota, Yoji Kukita, and Masahiro Inoue
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-16K10414
  • [Presentation] MIG6 contributes to hypoxia-induced dormancy in primary cultured lung cancer cells with EGFR active mutation2015

    • Author(s)
      遠藤 洋子
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-25461937
  • [Presentation] MIG6はEGFR活性変異型肺がん細胞の低酸素による休眠状態誘導に寄与する2015

    • Author(s)
      遠藤 洋子
    • Organizer
      第13回がんとハイポキシア研究会
    • Place of Presentation
      国立遺伝学研究所
    • Year and Date
      2015-06-05
    • Data Source
      KAKENHI-PROJECT-25461937
  • [Presentation] Inactive status of cancer cells with suppression of AKT activity contributes to survival in chronic hypoxia2014

    • Author(s)
      Masahiro Inoue, Hiroaki Okuyama, Hiroko Endo, Masayuki Ohue
    • Organizer
      American Association for Cancer Research(AACR) Annual Meeting  2014
    • Place of Presentation
      SanDiego Convention Center(USA)
    • Year and Date
      2014-04-06
    • Data Source
      KAKENHI-PROJECT-24300333
  • [Presentation] 肺がん初代培養細胞における低酸素下休眠状態の誘導メカニズム2014

    • Author(s)
      遠藤洋子, 奥山裕照, 井上正宏
    • Organizer
      第12回がんとハイポキシア研究会
    • Place of Presentation
      ホテルマリターレ創世佐賀(佐賀市)
    • Year and Date
      2014-11-21
    • Data Source
      KAKENHI-PROJECT-24300333
  • [Presentation] CTOS法による子宮頸部小細胞がん・腺がん混合腫瘍のクロナリティーの解析2014

    • Author(s)
      久保田 哲, 中嶋 綾, 清原 裕美子, 遠藤 洋子, 奥山 裕照, 井上 正宏
    • Organizer
      平成26年度文科省科研費新学術領域研究「がん研究分野の特性等を踏まえた支援活動」がん若手研究者ワークショップ
    • Place of Presentation
      蓼科グランドホテル滝の湯(茅野市)
    • Year and Date
      2014-09-06
    • Data Source
      KAKENHI-PROJECT-24300333
  • [Presentation] ヒト分化型大腸がんの初代培養スフェロイドにおける極性転換2014

    • Author(s)
      奥山裕照, 遠藤洋子, 井上正宏
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2014-09-26
    • Data Source
      KAKENHI-PROJECT-24300333
  • [Presentation] 子宮体がんの新規三次元培養CTOS法におけるmTOR阻害剤感受性の多様性2014

    • Author(s)
      清原裕美子, 遠藤洋子, 吉野 潔, 木村敏啓, 上田 豊, 藤田征巳, 木村 正, 井上正宏
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2014-09-27
    • Data Source
      KAKENHI-PROJECT-24300333
  • [Presentation] 新規3次元癌細胞初代培養(CTOS)法を用いた大腸癌に対するセツキシマブ感受性試験の検討2014

    • Author(s)
      多代尚広, 奥山裕照, 佐々木一雄, Piulats JM, 遠藤洋子, 河田健二, 駒田 徹, 大植雅之, 坂井義治, 井上正宏
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2014-09-27
    • Data Source
      KAKENHI-PROJECT-24300333
  • [Presentation] 肺がん初代培養細胞を用いた患者個人のALK阻害剤耐性機構の評価2014

    • Author(s)
      遠藤洋子, 西野和美, 熊谷 融, 奥山裕照, 今村文生, 井上正宏
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2014-09-25
    • Data Source
      KAKENHI-PROJECT-24300333
  • [Presentation] 癌細胞初代培養系(CTOS)における低酸素による休眠状態の誘導2013

    • Author(s)
      遠藤 洋子
    • Organizer
      第11回がんとハイポキシア研究会
    • Place of Presentation
      東北大学 片平さくらホール
    • Data Source
      KAKENHI-PROJECT-25461937
  • [Presentation] CTOS法を用いた肺がん初代培養系の確立と応用2012

    • Author(s)
      遠藤洋子
    • Organizer
      第23回大阪若手がんセミナー(FOCS)
    • Place of Presentation
      千里阪急ホテル(大阪)
    • Year and Date
      2012-07-13
    • Data Source
      KAKENHI-PROJECT-24300333
  • [Presentation] Hypoxia-induced tumor dormancy promotes cell survival through supPression of energy metabolism2012

    • Author(s)
      遠藤洋子
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      ロイトン札幌
    • Year and Date
      2012-09-20
    • Data Source
      KAKENHI-PROJECT-22791240
  • [Presentation] Influence of disruption on tissue remodeling in cancer tissue-originated spheroids(CTOS)2012

    • Author(s)
      Piulats R. Jose M, Okuyama H, Endo H, Inoue M
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      ロイトン札幌
    • Year and Date
      2012-09-19
    • Data Source
      KAKENHI-PROJECT-24300333
  • [Presentation] Analysis of radiosensitivity mechanisms in cervical cencer CTOS2012

    • Author(s)
      Nakajima A, Endo H, Okuyama H, Hiraoka M. Inoue M
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      ロイトン札幌
    • Year and Date
      2012-09-19
    • Data Source
      KAKENHI-PROJECT-24300333
  • [Presentation] Diverse response to heregulin and lapatinib between cancer tissue-originated spheroids from human urological cancer2012

    • Author(s)
      Okuyama H, Yoshida T, Endo H, Nakayama M, Nishimura K, Nonomura N, Inoue M
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      ロイトン札幌
    • Year and Date
      2012-09-19
    • Data Source
      KAKENHI-PROJECT-24300333
  • [Presentation] 低酸素によるがん細胞休眠状態の誘導2011

    • Author(s)
      遠藤洋子
    • Organizer
      第9回がんとハイポキシア研究会
    • Place of Presentation
      学習院大学目白キャンパス
    • Year and Date
      2011-11-26
    • Data Source
      KAKENHI-PROJECT-22791240
  • [Presentation] Prediction of therapeutic effect of EGFR TKI on lung cancer by a novel primary culture system2011

    • Author(s)
      遠藤洋子
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2011-10-03
    • Data Source
      KAKENHI-PROJECT-22791240
  • [Presentation] A novel primary culture system of cancer cells from lung cancer patients2010

    • Author(s)
      遠藤洋子
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2010-09-24
    • Data Source
      KAKENHI-PROJECT-22791240
  • [Presentation] Activation of IGF signaling under hypoxic conditions increases radiosensitivity in AsPC-1 cells through ER stress2007

    • Author(s)
      遠藤洋子
    • Organizer
      日本癌学会
    • Place of Presentation
      国内
    • Year and Date
      2007-10-04
    • Data Source
      KAKENHI-PROJECT-19790910
  • [Presentation] Activation of IGF signaling under hypoxic conditions increases radiosensitivity in AsPC-1 cells through ER stress2007

    • Author(s)
      遠藤 洋子
    • Organizer
      日本癌学会
    • Place of Presentation
      横浜
    • Year and Date
      2007-10-04
    • Data Source
      KAKENHI-PROJECT-19790910
  • [Presentation] Down-regulation of metabolism in cancer cells is an adaptive response to hypoxic conditions2007

    • Author(s)
      井上正宏, 遠藤洋子
    • Organizer
      日本癌学会
    • Place of Presentation
      横浜
    • Year and Date
      2007-10-04
    • Data Source
      KAKENHI-PROJECT-19590329
  • [Presentation] 癌細胞初代培養系(CTOS)における低酸素による休眠状態の誘導

    • Author(s)
      遠藤洋子, 奥山裕照, 井上正宏
    • Organizer
      第11回がんとハイポキシア研究会
    • Place of Presentation
      東北大学
    • Data Source
      KAKENHI-PROJECT-24300333
  • [Presentation] HIF-1αは放射線抵抗性の初代がん培養細胞において放射線照射後に発現が上昇する

    • Author(s)
      中嶋 綾, 遠藤洋子, 奥山裕照, 平岡真寛, 井上正宏
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-24300333
  • [Presentation] Neuregulin1/HER3シグナルは肺腺がん初代培養細胞の増殖を促進する

    • Author(s)
      遠藤洋子, 岡見次郎, 奥山裕照, 東山聖彦, 井上正宏
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-24300333
  • [Presentation] 低酸素環境下における癌細胞の休眠状態の誘導

    • Author(s)
      遠藤 洋子
    • Organizer
      第二回 癌と代謝研究会
    • Place of Presentation
      東京理科大学 葛飾キャンパス
    • Year and Date
      2014-07-10 – 2014-07-11
    • Data Source
      KAKENHI-PROJECT-25461937
  • [Presentation] 肺がん初代培養細胞における低酸素下休眠状態の誘導メカニズム

    • Author(s)
      遠藤 洋子
    • Organizer
      第12回 がんとハイポキシア研究会
    • Place of Presentation
      ホテルマリターレ創世佐賀
    • Year and Date
      2014-11-20 – 2014-11-21
    • Data Source
      KAKENHI-PROJECT-25461937
  • [Presentation] Hypoxia-induced tumor dormancy promotes cell survival through suppression of energy metabolism

    • Author(s)
      遠藤 洋子
    • Organizer
      日本癌学会
    • Place of Presentation
      ロイトン札幌
    • Data Source
      KAKENHI-PROJECT-22791240
  • [Presentation] 子宮頸部小細胞癌-初代培養細胞における放射線照射後のHIF-1α発現上昇は放射線抵抗性に関与する

    • Author(s)
      中嶋 綾, 遠藤洋子, 奥山裕照, 平岡真寛, 井上正宏
    • Organizer
      第11回がんとハイポキシア研究会
    • Place of Presentation
      東北大学
    • Data Source
      KAKENHI-PROJECT-24300333
  • 1.  INOUE Masahiro (10342990)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 37 results
  • 2.  OKUYAMA Hiroaki (50432373)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 17 results
  • 3.  近藤 純平 (80624593)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 4.  富田 裕彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 5.  荒井 雅吉
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 6.  古徳 直之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 7.  小林 資正
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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