OHIKE Yumiko 大池裕美子

Researcher Number	20359615
Affiliation (based on the past Project Information) *help	2008: 東京大学, 医学部・附属病院, 助教 2007: 東京大学, 医学部附属病院, 助教 2005: The University of Tokyo, Faculty of Medicine, Assistant, 医学部附属病院, 助手 2005: 東京大学, 医学部附属病院, 教務技官 2003 – 2004: The University of Tokyo, Faculty of Medicine, Assistant, 医学部附属病院, 教務職員
Review Section/Research Field	Principal Investigator Metabolomics Except Principal Investigator Circulatory organs internal medicine / Circulatory organs internal medicine
Keywords	Principal Investigator ERアンタゴニスト / アポトーシス / サイクリンA / ERβ / ERα / ラロキシフェン / エストロゲン / エストロゲン調節遺伝子 / 血管平滑筋細胞 / 動脈硬化 / 新生内膜形成抑制 / 低濃度エストロゲン … More Except Principal Investigator … More Gas6 / アポトーシス / 血管石灰化 / apoptosis / Na-dependent Pi cotransporter / human aortic smooth muscle cells / vascular calcification / 糖尿病 / ヒト大動脈由来血管平滑筋細胞 / AGE / デキサメサゾン / VitD3 / 石灰化 / ビスフォスフォネート / GAS / 平滑筋細胞石灰化 / スタチン / Na依存性リン共輸送体 / DNA chip / adeno virus vector / vascular smooth muscle cells / estrogen receptor / 骨量 / トランジェニックラット / 卵巣摘除 / マイクロアレイ / ERβ / ERα / ラロキシフェン / エストロゲン / 動脈硬化 / DNAチップ / アデノウィルスベクター / 血管平滑筋細胞 / エストロゲン受容体 / Gas6-Axl経路 / Gas6-x1 / 細胞アポトーシス / Gas6-Axl / 高リン血症 Less

Vascular calcification by restoring Gas6-Axl survival pathway
- Principal Investigator
  
  IIJIMA Katsuya
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  The University of Tokyo
血管傷害保護におけるエストロゲン受容体サブタイプの役割の解明と治療への応用Principal Investigator
- Principal Investigator
  
  大池裕美子
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo
Molecular mechanisms and novel therapeutic approaches for cardiovascular calcification
- Principal Investigator
  
  OUCHI Yasuyoshi
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  The University of Tokyo
Investigation and clinical application to the prevention of estrogen receptor α and β prevent vascular disease.
- Principal Investigator
  
  OUCHI Yasuyoshi
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  The University of Tokyo

All 2008 2007 2005 2004

All Journal Article Presentation

[Journal Article] Association ofplasma dehydroepiandrosterone-sulfate levelswith endothelial function in postmenopausalwomen with coronary risk factors2008
- Author(s)
  Akishita M, Hashimoto M, Ohike Y, Ogawa S,Iijima K, Eto M, Ouchi Y.
- Journal Title
  
  Hypertens Res 31(1)
  
  Pages: 69-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590854
[Journal Article] Low testosteronelevel is an independent determinant ofendothelial dysfunction in men2007
- Author(s)
  Akishita M, Hashimoto M, Ohike Y, OgawaS, Iijima K, Eto M, Ouchi Y.
- Journal Title
  
  Hypertens Res 30(11)
  
  Pages: 1029-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590854
[Journal Article] Amelioration of vascular endothelial dysfunction in obstructive sleep apnea syndrome by nasal continuous positive airway pressure--possible involvement of nitric oxide and asymmetric NG, NG-dimethylarginine.2005
- Author(s)
  Ohike Y, Kozaki K, Ouchi Y, et al.
- Journal Title
  
  Circ J. 69(2)
  
  Pages: 221-226
- NAID
  110002696075
- Data Source
  KAKENHI-PROJECT-15790463
[Journal Article] Amelioration of vascular endothelial dysfunction in obstructive sleep apnea syndrome by nasal continuous positive airway pressure--possible involvement of nitric oxide and asymmetric NG, NG-dimethylarginine2005
- Author(s)
  Ohike Y, Kozaki K, Ouchi Y, et al.
- Journal Title
  
  Circ J 69(2)
  
  Pages: 221-226
- NAID
  110002696075
- Data Source
  KAKENHI-PROJECT-15390239
[Journal Article] Amelioration of vascular endothelial dysfunction in obstructive sleep apnea syndrome by nasal continuous positive airway pressure--possible involvement of nitric oxide and asymmetric NG. NG-dimethvlarginine2005
- Author(s)
  Ohike Y, Kozaki K, Ouchi Y, et al.
- Journal Title
  
  Circ J 69(2)
  
  Pages: 211-6
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390239
[Journal Article] Amelioration of vascular endothelial dysfunction in obstructive sleep apnea syndrome by nasal continuous positive airway pressure--possible involvement of nitric oxide and asymmetric NG, NG-dimethylarginine.2005
- Author(s)
  Ohike Y, Kozaki K, Iijima K, Eto M, Kojima T, Ohga E, Santa T, Imai K, Hashimoto M, Yoshizumi M, Ouchi Y.
- Journal Title
  
  Circ J. 69(2)
  
  Pages: 221-226
- NAID
  110002696075
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390239
[Journal Article] Amelioration of vascular endothelial dysfunction in obstructive sleep apnea syndrome by nasal continuous positive airway pressure--possible involvement of nitric oxide and asymmetric NG, NG-dimethylarginine.2005
- Author(s)
  Ohike Y, Kozaki K, Ouchi Y, et al.
- Journal Title
  
  Circ J. 69(2)
  
  Pages: 221-226
- NAID
  110002696075
- Data Source
  KAKENHI-PROJECT-15390239
[Journal Article] ラット頸動脈バルン傷害モデルにおける新生内膜肥厚に対する低用量エストロゲンの抑制効果2004
- Author(s)
  渡辺徳光, 神崎恒一, 大池裕美子, 他
- Journal Title
  
  第36回日本動脈硬化学会総会プログラム・抄録集
  
  Pages: 227-227
- Data Source
  KAKENHI-PROJECT-15790463
[Journal Article] HMG Co-A還元酵素阻害薬(スタチン)によるヒト培養血管平滑筋細胞石灰化の抑制作用2004
- Author(s)
  孫輔卿, 神崎恒一, 大池裕美子, 他
- Journal Title
  
  第36回日本動脈硬化学会総会プログラム・抄録集
  
  Pages: 189-189
- Data Source
  KAKENHI-PROJECT-15790463
[Journal Article] 高齢入院患者における生活習慣病合併頻度の年次推移2004
- Author(s)
  小島太郎, 神崎恒一, 大池裕美子, 他
- Journal Title
  
  日本老年医学会雑誌 41(Suppl)
  
  Pages: 116-116
- Data Source
  KAKENHI-PROJECT-15790463
[Journal Article] HMG Co-A還元酵素阻害薬(スタチン)によるヒト培養血管平滑筋細胞石灰化の抑制作用2004
- Author(s)
  孫輔卿, 神崎恒一, 大池裕美子, 他
- Journal Title
  
  第36回日本動脈硬化学会総会プログラム・抄録集
  
  Pages: 189-189
- Data Source
  KAKENHI-PROJECT-15390239
[Journal Article] 高齢者糖尿病の長期予後予測における血流依存性血管拡張反応(Flow-mediated dilatation ; FMD)の意義2004
- Author(s)
  大池裕美子, 神崎恒一, 大内尉義, 他
- Journal Title
  
  日本内科学会雑誌 93(Suppl)
  
  Pages: 181-181
- Data Source
  KAKENHI-PROJECT-15790463
[Journal Article] 高齢者糖尿病の長期予後予測における血流依存性血管拡張反応(Flow-mediated dilatation ; FMD)の意義2004
- Author(s)
  大池裕美子, 神崎恒一, 大内尉義, 他
- Journal Title
  
  日本老年医学会雑誌 41(Suppl)
  
  Pages: 115-115
- Data Source
  KAKENHI-PROJECT-15790463
[Presentation] 高齢者の動脈硬化危険因子の重複に内臓脂肪が及ぼす影響に関する臨床研究2007
- Author(s)
  野村和至, 秋下雅弘, 中村哲郎, 山田優子, 小島太郎, 大池裕美子, 飯島勝矢, 荒木厚, 江頭正人, 大内尉義
- Organizer
  第104回日本内科学会総会・講演会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19590854
[Presentation] 高齢者の腹部大動脈石灰化と腎機能障害との関連についての検討2007
- Author(s)
  野村和至, 秋下雅弘, 中村哲郎, 小島太郎, 大池裕美子, 飯島勝矢, 江頭正人, 大内尉義
- Organizer
  第39回日本動脈硬化学会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19590854
[Presentation] Obstructivesleep apnea exacerbates endothelialdysfunction in patients with metabolicsyndrome2007
- Author(s)
  Akishita M, Ohike Y, Hashimoto M, Iijima K,Eto M, Teramoto S, Ouchi Y.
- Organizer
  Scientific Sessions of AmericanHeart Association, Orlando
- Place of Presentation
  USA
- Data Source
  KAKENHI-PROJECT-19590854
[Presentation] Angiotensin-II receptorblocker enhances the inhibitory effect ofstatins on vascular calcification in uremic ratsinduced by adenine diet2007
- Author(s)
  飯島勝矢、伊藤友紀、孫輔卿、江頭正人、小川純人、大池由美子、小島太郎、大田秀隆、野村和至、橋本寛子、山田容子、秋下雅弘、大内尉義
- Organizer
  第71回日本循環器学会総会・学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19590854
[Presentation] 慢性腎臓病CKDにおける心血管石灰化2007
- Author(s)
  飯島勝矢, 孫輔卿, 伊藤友紀, 江頭正人, 大池裕美子, 小島太郎, 大田秀隆, 野村和至, 秋下雅弘, 大内尉義
- Organizer
  第39回日本動脈硬化学会総会
- Place of Presentation
  大阪
- Year and Date
  2007-07-13
- Data Source
  KAKENHI-PROJECT-19590854
[Presentation] The associationof polypharmacy and hypertension with fallrisks among the elderly patients2007
- Author(s)
  Kojima T, Akishita M, Yamaguchi K, OhikeY, Iijima K, Eto M, Ouchi Y.
- Organizer
  The 8thAsia/Oceania Regional Congress ofGerontology and Geriatrics
- Place of Presentation
  Beijing
- Data Source
  KAKENHI-PROJECT-19590854

1. IIJIMA Katsuya (00334384)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
2. OUCHI Yasuyoshi (80168864)

# of Collaborated Projects: 3 results

# of Collaborated Products: 12 results
3. ETO Masato (80282630)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
4. KOZAKI Koichi (80272540)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
5. WATANABE Tokurnitsu

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. OGAWA Sumito (20323579)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. AKISHITA Masahiro (00261975)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
8. OTA Hidetaka (20431869)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. INOUE Satoshi (40251251)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. KOJIMA Taro (40401111)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

OHIKE Yumiko 大池 裕美子

Research Projects

Research Products

Co-Researchers

Vascular calcification by restoring Gas6-Axl survival pathway

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

血管傷害保護におけるエストロゲン受容体サブタイプの役割の解明と治療への応用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanisms and novel therapeutic approaches for cardiovascular calcification

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation and clinical application to the prevention of estrogen receptor α and β prevent vascular disease.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Association ofplasma dehydroepiandrosterone-sulfate levelswith endothelial function in postmenopausalwomen with coronary risk factors2008

Author(s)

Journal Title

Data Source

[Journal Article] Low testosteronelevel is an independent determinant ofendothelial dysfunction in men2007

Author(s)

Journal Title

Data Source

[Journal Article] Amelioration of vascular endothelial dysfunction in obstructive sleep apnea syndrome by nasal continuous positive airway pressure--possible involvement of nitric oxide and asymmetric NG, NG-dimethylarginine.2005

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Amelioration of vascular endothelial dysfunction in obstructive sleep apnea syndrome by nasal continuous positive airway pressure--possible involvement of nitric oxide and asymmetric NG, NG-dimethylarginine2005

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Amelioration of vascular endothelial dysfunction in obstructive sleep apnea syndrome by nasal continuous positive airway pressure--possible involvement of nitric oxide and asymmetric NG. NG-dimethvlarginine2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Amelioration of vascular endothelial dysfunction in obstructive sleep apnea syndrome by nasal continuous positive airway pressure--possible involvement of nitric oxide and asymmetric NG, NG-dimethylarginine.2005

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] Amelioration of vascular endothelial dysfunction in obstructive sleep apnea syndrome by nasal continuous positive airway pressure--possible involvement of nitric oxide and asymmetric NG, NG-dimethylarginine.2005

Author(s)

Journal Title

NAID

Data Source

[Journal Article] ラット頸動脈バルン傷害モデルにおける新生内膜肥厚に対する低用量エストロゲンの抑制効果2004

Author(s)

Journal Title

Data Source

[Journal Article] HMG Co-A還元酵素阻害薬(スタチン)によるヒト培養血管平滑筋細胞石灰化の抑制作用2004

Author(s)

Journal Title

Data Source

[Journal Article] 高齢入院患者における生活習慣病合併頻度の年次推移2004

Author(s)

Journal Title

Data Source

[Journal Article] HMG Co-A還元酵素阻害薬(スタチン)によるヒト培養血管平滑筋細胞石灰化の抑制作用2004

Author(s)

Journal Title

Data Source

[Journal Article] 高齢者糖尿病の長期予後予測における血流依存性血管拡張反応(Flow-mediated dilatation ; FMD)の意義2004

Author(s)

OHIKE Yumiko 大池裕美子