SUICO MARY ANN SOTEN スイコメリー・アン・ソテン

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SUICO Mary Ann Soten スイコメリー・アン・ソテン

MARY ANN Suico メリーアンスイコ

ANN SOTEN Suico mary アン・ソテンスイコ・メリー

スイコメリーアン・ソテンスイコメリー・アン・ソテン

SUICO MARY Ann Soten スイコ・メリーアン・ソテン

スイコメリー・アン・ソテンスイコメリーアンソテン

SUICO Mary Ann スイコメアリーアン

メリー・アンスイコメリー・アンスイコ

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Researcher Number	20363525
Other IDs
Affiliation (Current)	2025: 熊本大学, 大学院生命科学研究部附属グローバル天然物科学研究センター, 助教
Affiliation (based on the past Project Information) *help	2018 – 2024: 熊本大学, 大学院生命科学研究部附属グローバル天然物科学研究センター, 助教 2013 – 2017: 熊本大学, 大学院生命科学研究部(薬), 助教 2015: 熊本大学, その他の研究科, 助教 2015: 熊本大学, 大学院生命科学研究部(薬学系), 助教 2013: 熊本大学, その他の研究科, 助教 … More 2012: 熊本大学, 大学院生命科学研究部, 助教 2009 – 2012: Kumamoto University, 大学院・生命科学研究部, 助教 2011: 熊本大学, 生命科学研究部, 助教 2007 – 2008: 熊本大学, 大学院・医学薬学研究部, 助教 2006: 熊本大学, 大学院・医学薬学研究部, 助手 2005 – 2006: 熊本大学, 大学院医学薬学研究部, 助手 Less
Review Section/Research Field	Principal Investigator Biological pharmacy / Basic Section 47040:Pharmacology-related / Pharmacology in pharmacy Except Principal Investigator Basic Section 48030:Pharmacology-related / Basic Section 47040:Pharmacology-related / Pharmacology in pharmacy / Biological pharmacy / Medical pharmacy / Biological Sciences
Keywords	Principal Investigator p53 / MEF / 薬理学 / Sp1 / プロモーター / Myeloid elf-1 like factor (MEF) / 転写因子 / 癌抑制遺伝子 / HiBiT NanoLuc system / ハイスループットスクリーニング … More / フィンランド型先天性ネフローゼ症候群 (CNF) / 糸球体上皮細胞 (ポドサイト) / HiBiT-Nephrin / 化合物スクリーニング / Nephrin / 腎糸球体 / ネフローゼ症候群 / IV型コラーゲン / アカデミア創薬 / HTSスクリーニング / Ⅳ型コラーゲン / アルポート症候群 / 慢性腎疾患 / ノックアウトマウス / FSGS / 抗体 / ポドサイト / モデルマウス / CKD / podocyte / 物理刺激 / ミトコンドリア / 慢性腎臓病 / 分子生物学 / 翻訳後発現制御 / Rb / MDM2 / 翻訳後発現調節 / ETS転写因子 / HIF1 / 低酸素 / がん抑制遺伝子 / Meloid elf-1 like factor(MEF) / 転写 / E2F1 / p21 / E2F / ETS / DNAメチル化 / perforin / lysozyme / プロモーター活性 / SUMO / 翻訳後修飾 / Myeloid elf-1 like factor(MEF) … More Except Principal Investigator IV型コラーゲン / Alport症候群 / 創薬 / Ⅳ型コラーゲン / アルポート症候群 / ENaC / アミロイド / 小胞体 / mucin / phosphatidic acid / transthyretin / CFTR / FAP / cystic fibrosis / 遺伝病 / タンパク質 / 薬理学 / collagen / モデルマウス / Alisporivir / ミスセンス変異 / CKD / type 4 collagen / alport / kidney / 表現型 / 遺伝子型 / Split NanoLuciferase / Type IV collagen / トランスサイレチン / アミロイドーシス / 家族性アミロイドポリニューロパチー / 化合物ライブラリースクリーニング / amyloidosis / toll-like receptor / calnexin / BiP / 小胞体関連分解(ERAD) / transthyretin(TTR) / calnexin(CNX) / 家族性アミロイドポリニューロパチー(FAP) / 嚢胞性線維症(CF) / シグナル伝達 / 生物物理 / 生体分子 / 免疫学 / 蛋白質 / 免疫 / 分子認識機構 / 構造生物学 / 結晶構造 / 複合体 / サイトカイン受容体 / サイトカイン Less

Therapeutic screening and molecular basis for Congenital Nephrotic Syndrome of the Finish type (CNF)Principal Investigator
- Principal Investigator
  
  スイコメリー・アン・ソテン
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Kumamoto University
Advanced research on the original drug discovery platform for hereditary intractable Alport syndrome
- Principal Investigator
  
  甲斐広文
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Kumamoto University
Molecular basis on drug development targeting causative molecules of genetic nephritis Alport syndromePrincipal Investigator
- Principal Investigator
  
  Suico Mary Ann
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Kumamoto University
Establishment of research platform for the development of renal precision medicine
- Principal Investigator
  
  Kai Hirofumi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Kumamoto University
Molecular basis and clinical implication of podocyte MEF-p53 network in CKD pathogenesisPrincipal Investigator
- Principal Investigator
  
  Suico Mary Ann Soten
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Kumamoto University
The role of transcription factors p53 and MEF in a mouse model of chronic kidney disease (CKD)Principal Investigator
- Principal Investigator
  
  Suico Mary Ann
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Kumamoto University
Drug discovery for Familial amyloid polyneuropathy (FAP), an incurable hereditary disease
- Principal Investigator
  
  KAI HIROFUMI
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Kumamoto University
Regulatory mechanism of expression of ETS transcription factor Myeloid elf-1-like factor (MEF) by tumor suppressorsPrincipal Investigator
- Principal Investigator
  
  SUICO Mary Ann Soten
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kumamoto University
Drug development on protein misfolding diseases
- Principal Investigator
  
  KAI Hirofumi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kumamoto University
Molecular Basis of the regulation of ETS transcription factor MEF expression by tumor suppressor gene p53Principal Investigator
- Principal Investigator
  
  ANN SOTEN Suico mary
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kumamoto University
Therapeutic principles on protein misfolding diseases
- Principal Investigator
  
  KAI Hirofumi
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kumamoto University
IL-2/IL-2R複合体形成機構の構造生物学的研究
- Principal Investigator
  
  池水信二
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kumamoto University
X染色体上の新規ガン抑制遺伝子MEFに関する研究Principal Investigator
- Principal Investigator
  
  メリー・アンスイコ
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kumamoto University

[Journal Article] Combinatorial screening for therapeutics in ATTRv amyloidosis identifies naphthoquinone analogues as TTR-selective amyloid disruptors2023
- Author(s)
  Sasaki Ryoko、Suico Mary Ann、Chosa Keisuke、Teranishi Yuriko、Sato Takashi、Kagami Asuka、Kotani Shunsuke、Kato Hikaru、Hitora Yuki、Tsukamoto Sachiko、Yamashita Tomohiro、Yokoyama Takeshi、Mizuguchi Mineyuki、Kai Hirofumi、Shuto Tsuyoshi
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 151 Issue: 1 Pages: 54-62
- DOI
  10.1016/j.jphs.2022.11.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07086, KAKENHI-PROJECT-23K06150, KAKENHI-PROJECT-23K06165
[Journal Article] CyclosporinA Derivative as Therapeutic Candidate for Alport Syndrome by Inducing Mutant Type IV Collagen Secretion2023
- Author(s)
  Kuwazuru Jun、Suico Mary Ann、Omachi Kohei、Kojima Haruka、Kamura Misato、Kaseda Shota、Kawahara Teppei、Hitora Yuki、Kato Hikaru、Tsukamoto Sachiko、Wada Mikiyo、Asano Toshifumi、Kotani Shunsuke、Nakajima Makoto、Misumi Shogo、Sannomiya Yuya、Horizono Jun、Koyama Yuimi、Owaki Aimi、Shuto Tsuyoshi、Kai Hirofumi
- Journal Title
  
  Kidney360
  
  Volume: 4 Pages: 909-917
- DOI
  10.34067/kid.0000000000000134
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06150, KAKENHI-PROJECT-23K06165, KAKENHI-PROJECT-23K20310
[Journal Article] Seamless Gene Correction in the Human Cystic Fibrosis Transmembrane Conductance Regulator Locus by Vector Replacement and Vector Insertion Events2022
- Author(s)
  Suzuki Shingo、Chosa Keisuke、Barill Cristina、Yao Michael、Zuffardi Orsetta、Kai Hirofumi、Shuto Tsuyoshi、Suico Mary Ann、Kan Yuet W.、Sargent R. Geoffrey、Gruenert Dieter C.
- Journal Title
  
  Frontiers in Genome Editing
  
  Volume: 4 Pages: 843885-843885
- DOI
  10.3389/fgeed.2022.843885
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07086
[Journal Article] The role of discoidin domain receptor 2 in the renal dysfunction of alport syndrome mouse model2021
- Author(s)
  Sannomiya Yuya、Kaseda Shota、Kamura Misato、Yamamoto Hiroshi、Yamada Hiroyuki、Inamoto Masataka、Kuwazuru Jun、Niino Saki、Shuto Tsuyoshi、Suico Mary Ann、Kai Hirofumi
- Journal Title
  
  Renal Failure
  
  Volume: 43 Issue: 1 Pages: 510-519
- DOI
  10.1080/0886022x.2021.1896548
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07086, KAKENHI-PROJECT-19H03379, KAKENHI-PROJECT-19J23608
[Journal Article] Type IV Collagen Variants in CKD: Performance of Computational Predictions for Identifying Pathogenic Variants2021
- Author(s)
  Shulman Cole、Liang Emerald、Kamura Misato、Udwan Khalil、Yao Tony、Cattran Daniel、Reich Heather、Hladunewich Michelle、Pei York、Savige Judy、Paterson Andrew D.、Suico Mary Ann、Kai Hirofumi、Barua Moumita
- Journal Title
  
  Kidney Medicine
  
  Volume: 3 Issue: 2 Pages: 257-266
- DOI
  10.1016/j.xkme.2020.12.007
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03379
[Journal Article] Metformin ameliorates the severity of experimental Alport syndrome2021
- Author(s)
  Omachi Kohei、Kaseda Shota、Yokota Tsubasa、Kamura Misato、Teramoto Keisuke、Kuwazuru Jun、Kojima Haruka、Nohara Hirofumi、Koyama Kosuke、Ohtsuki Sumio、Misumi Shogo、Takeo Toru、Nakagata Naomi、Li Jian-Dong、Shuto Tsuyoshi、Suico Mary Ann、Miner Jeffrey H.、Kai Hirofumi
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1
- DOI
  10.1038/s41598-021-86109-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07086, KAKENHI-PROJECT-19H03379, KAKENHI-PROJECT-19J23608
[Journal Article] Activation of heat shock response improves biomarkers of NAFLD in patients with metabolic diseases2021
- Author(s)
  Kondo Tatsuya、Miyakawa Nobukazu、Kitano Sayaka、Watanabe Takuro、Goto Rieko、Suico Mary Ann、Sato Miki、Takaki Yuki、Sakaguchi Masaji、Igata Motoyuki、Kawashima Junji、Motoshima Hiroyuki、Matsumura Takeshi、Kai Hirofumi、Araki Eiichi
- Journal Title
  
  Endocrine Connections
  
  Volume: 10 Issue: 5 Pages: 521-533
- DOI
  10.1530/ec-21-0084
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03379, KAKENHI-PROJECT-20K07086, KAKENHI-PROJECT-21K08533
[Journal Article] Novel Keap1-Nrf2 Protein-protein interaction inhibitor UBE-1099 Ameliorates Progressive Phenotype in Alport Syndrome mouse model2021
- Author(s)
  Kaseda Shota、Sannomiya Yuya、Horizono Jun、Kuwazuru Jun、Suico Mary Ann、Ogi Sayaka、Sasaki Ryoko、Sunamoto Hidetoshi、Fukiya Hirohiko、Nishiyama Hayato、Kamura Misato、Niinou Saki、Koyama Yuimi、Nara Futoshi、Shuto Tsuyoshi、Onuma Kazuhiro、Kai Hirofumi
- Journal Title
  
  Kidney360
  
  Volume: - Issue: 4 Pages: 687-699
- DOI
  10.34067/kid.0004572021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03379, KAKENHI-PROJECT-20K07086
[Journal Article] Melinjo seed extract increases adiponectin multimerization in physiological and pathological conditions.2020
- Author(s)
  K. Oniki, T. Kawakami, A. Nakashima, K. Miyata, T. Watanabe, H. Fujikawa, R. Nakashima, A. Nasu, Y. Eto, N. Takahashi, H. Nohara, M. Ann Suico, S. Kotani, Y. Obata, Y. Sakamoto, Y. Seguchi, J. Saruwatari, T. Imafuku, H. Watanabe, T. Maruyama, H. Kai, T. Shuto
- Journal Title
  
  Scientific reports
  
  Volume: 10 Issue: 1 Pages: 4313-4313
- DOI
  10.1038/s41598-020-61148-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06997, KAKENHI-PROJECT-19K07166, KAKENHI-PROJECT-19K08560, KAKENHI-PROJECT-17H03570, KAKENHI-PROJECT-19H03379, KAKENHI-PROJECT-17K08309
[Journal Article] Azithromycin Inhibits Constitutive Airway Epithelial Sodium Channel Activation in Vitro and Modulates Downstream Pathogenesis in Vivo2020
- Author(s)
 Haruka Fujikawa, Taise Kawakami, Ryunosuke Nakashima, Aoi Nasu, Shunsuke Kamei, Hirofumi Nohara, Yuka Eto, Keiko Ueno-Shuto, Toru Takeo, Naomi Nakagata, Mary Ann Suico, Hirofumi Kai, Tsuyoshi Shuto.
- Journal Title
 
 Biological and Pharmaceutical Bulletin
 
 Volume: 43 Issue: 4 Pages: 725-730
- DOI
 10.1248/bpb.b19-01091
- NAID
 130007825345
- ISSN
 0918-6158, 1347-5215
- Year and Date
 2020-04-01
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-19K07114, KAKENHI-PROJECT-17H03570, KAKENHI-PROJECT-19H03379, KAKENHI-PROJECT-17K08309
[Journal Article] Trimerization and genotype-phenotype correlation of COL4A5 mutants in Alport syndrome2020
- Author(s)
  Kamura Misato、Yamamura Tomohiko、Omachi Kohei、Suico Mary Ann、Nozu Kandai、Kaseda Shota、Kuwazuru Jun、Shuto Tsuyoshi、Iijima Kazumoto、Kai Hirofumi
- Journal Title
  
  Kidney International Reports
  
  Volume: - Issue: 5 Pages: 718-726
- DOI
  10.1016/j.ekir.2020.01.008
- NAID
  120006818746
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03570, KAKENHI-PROJECT-19H03379, KAKENHI-PROJECT-19J15443, KAKENHI-PROJECT-17K08309, KAKENHI-PROJECT-19K08726
[Journal Article] Mild electrical stimulation with heat shock attenuates renal pathology in adriamycin-induced nephrotic syndrome mouse model2020
- Author(s)
  Teramoto Keisuke、Tsurekawa Yu、Suico Mary Ann、Kaseda Shota、Omachi Kohei、Yokota Tsubasa、Kamura Misato、Piruzyan Mariam、Kondo Tatsuya、Shuto Tsuyoshi、Araki Eiichi、Kai Hirofumi
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 18719-18719
- DOI
  10.1038/s41598-020-75761-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03379, KAKENHI-PROJECT-19J23608, KAKENHI-PROJECT-18K08482, KAKENHI-PROJECT-20H01036
[Journal Article] Therapeutic strategy to target collagen IV α3α4α5 in Alport syndrome2019
- Author(s)
  大町紘平、Suico Mary Ann、首藤剛、甲斐広文
- Journal Title
  
  生化学
  
  Volume: 91 Issue: 3 Pages: 413-417
- DOI
  10.14952/SEIKAGAKU.2019.910413
- ISSN
  0037-1017
- Year and Date
  2019-06-25
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03570, KAKENHI-PROJECT-19H03379, KAKENHI-PROJECT-17K08309
[Journal Article] Transthyretin Amyloid Fibril Disrupting Activities of Extracts and Fractions from Juglans mandshurica Maxim. var. cordiformis (Makino) Kitam.2019
- Author(s)
  Chaudhary N., Sasaki, R., Shuto, T., Watanabe, M., Kawahara, T., Suico, M.A., Yokoyama, T., Mizuguchi, M., Kai, H., Devkota, H.
- Journal Title
  
  Molecules
  
  Volume: 24 Issue: 3 Pages: 500-500
- DOI
  10.3390/molecules24030500
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08309, KAKENHI-PROJECT-16K08193
[Journal Article] Auto-measure emphysematous parameters and pathophysiological gene expression profiles in experimental mouse models of acute and chronic obstructive pulmonary diseases2019
- Author(s)
  Nakashima R, Kamei S, Nohara H, Fujikawa H, Maruta K, Kawakami T, Eto Y, Takahashi N, Suico M.A., Takeo T, Nakagawa N, Kai H, Shuto T.
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 140 Issue: 2 Pages: 113-119
- DOI
  10.1016/j.jphs.2019.01.011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03379, KAKENHI-PROJECT-17K08309
[Journal Article] A split-luciferase-based trimer formation assay as a high-throughput screening platform for therapeutics in Alport syndrome2018
- Author(s)
  Kohei Omachi, Misato Kamura, Keisuke Teramoto, Haruka Kojima, Tsubasa Yokota, Shota Kaseda, Jun Kuwazuru, Ryosuke Fukuda, Kosuke Koyama, Shingo Matsuyama, Keishi Motomura, Tsuyoshi Shuto, Mary Ann Suico and Hirofumi Kai.
- Journal Title
  
  Cell Chem Biol.
  
  Volume: 印刷中 Issue: 5 Pages: 634-643.e4
- DOI
  10.1016/j.chembiol.2018.02.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08309, KAKENHI-PROJECT-17H03570, KAKENHI-PROJECT-17J11628, KAKENHI-PROJECT-16K15163
[Journal Article] STAT3 inhibition attenuates the progressive phenotypes of Alport syndrome mouse model.2018
- Author(s)
  Yokota T, Omachi K, Suico MA, Kamura M, Kojima H, Fukuda R, Motomura K, Teramoto K, Kaseda S, Kuwazuru J, Takeo T, Nakagata N, Shuto T, Kai H.
- Journal Title
  
  Nephrol Dial Transplant
  
  Volume: 33(2) Issue: 2 Pages: 214-223
- DOI
  10.1093/ndt/gfx246
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08309
[Journal Article] Mild electrical stimulation with heat shock reduces inflammatory symptoms in the imiquimod-induced psoriasis mouse model.2018
- Author(s)
  Tsurekawa Y, Morita M, Suico MA, Moriuchi M, Nakano Y, Piruzyan M, Takada M, Fukami S, Shuto T, Kai H.
- Journal Title
  
  Experimental Dermatology
  
  Volume: 27 Issue: 10 Pages: 1092-1097
- DOI
  10.1111/exd.13720
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08309
[Journal Article] Taurine Inhibits TRPV-Dependent Activity to Overcome Oxidative Stress in Caenorhabditis elegans2018
- Author(s)
 Moriuchi M, Nakano Y, Tsurekawa Y, Piruzyan M, Matsuyama S, Nohara H, Suico MA, Shuto T, Kai H.
- Journal Title
 
 Biological and Pharmaceutical Bulletin
 
 Volume: 41 Issue: 11 Pages: 1672-1677
- DOI
 10.1248/bpb.b18-00370
- NAID
 40021701358
- ISSN
 0918-6158, 1347-5215
- Year and Date
 2018-11-01
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-17K08309
[Journal Article] Bromide supplementation exacerbated the renal dysfunction, injury and fibrosis in a mouse model of Alport syndrome.2017
- Author(s)
  Yokota T, Omachi K, Suico MA, Kojima H, Kamura M, Teramoto K, Kaseda S, Kuwazuru J, Shuto T, Kai H.
- Journal Title
  
  PLoS One.
  
  Volume: 12(9) Issue: 9 Pages: e0183959-e0183959
- DOI
  10.1371/journal.pone.0183959
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08309
[Journal Article] Roles and regulations of the ETS transcription factor ELF4/MEF.2017
- Author(s)
  Suico MA, Shuto T, Kai H.
- Journal Title
  
  J Mol Cell Biol.
  
  Volume: 印刷中 Pages: 168-177
- DOI
  10.1093/jmcb/mjw051
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460098, KAKENHI-PROJECT-17K08309
[Journal Article] Long-term treatment with EGFR inhibitor erlotinib attenuates renal inflammatory cytokines but not nephropathy in Alport syndrome mouse model.2017
- Author(s)
  Omachi K, Miyakita R, Fukuda R, Kai Y, Suico MA, Yokota T, Kamura M, Shuto T, Kai H.
- Journal Title
  
  Clin Exp Nephrol.
  
  Volume: 印刷中 Issue: 6 Pages: 952-960
- DOI
  10.1007/s10157-017-1386-9
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460098, KAKENHI-PROJECT-17K08309
[Journal Article] The ETS Factor Myeloid Elf-1-Like Factor (MEF)/Elf4 Is Transcriptionally and Functionally Activated by Hypoxia2016
- Author(s)
  Suico MA, Taura M, Kudo E, Gotoh K, Shuto T, Okada S, Kai H.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 39 Issue: 4 Pages: 641-647
- DOI
  10.1248/bpb.b15-00796
- NAID
  130005141679
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-14J01801, KAKENHI-PROJECT-26460098, KAKENHI-PROJECT-16K15163
[Journal Article] Activation of heat shock response to treat obese subjects with type 2 diabetes: a prospective, frequency-escalating, randomized, open-label, triple-arm trial.2016
- Author(s)
  Kondo T, Goto R, Ono K, Kitano S, Suico MA, Sato M, Igata M, Kawashima J, Motoshima H, Matsumura T, Kai H, Araki E.
- Journal Title
  
  Sci Rep.
  
  Volume: 19 Issue: 1 Pages: 35690-35690
- DOI
  10.1038/srep35690
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460098, KAKENHI-PROJECT-15K12514, KAKENHI-PROJECT-15K09394, KAKENHI-PROJECT-16K09759
[Journal Article] The effect of mild electrical stimulation with heat shock on diabetic KKAy mice.2015
- Author(s)
  Kai Y, Tsurekawa Y, Fukuda R, Omachi K, Piruzyan M, Okamoto Y, Motomura K, Suico MA, Shuto T, Kondo T, Araki E, Kai H.
- Journal Title
  
  Integr Mol Med.
  
  Volume: 3 Issue: 1 Pages: 473-477
- DOI
  10.15761/imm.1000190
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460098, KAKENHI-PROJECT-15K12514, KAKENHI-PROJECT-25253012, KAKENHI-PROJECT-15J09868
[Journal Article] Podocyte p53 limits the severity of experimental Alport syndrome.2015
- Author(s)
  Fukuda R., et al.
- Journal Title
  
  Jounal of American Society of Nephrology
  
  Volume: just accepted Issue: 1 Pages: 144-157
- DOI
  10.1681/asn.2014111109
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25860223, KAKENHI-PROJECT-26460098, KAKENHI-PROJECT-15K12514, KAKENHI-PROJECT-15K19032, KAKENHI-PROJECT-25460102
[Journal Article] Structural stabilization of transthyretin by a new compound, 6-benzoyl-2-hydroxy-1H-benzo[de]isoquinoline-1,3(2H)-dione2015
- Author(s)
  Yokoyama T, Takaki S, Chosa K, Sato T, Suico MA, Teranishi Y, Shuto T, Mizuguchi M, Kai H
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: 129 Issue: 4 Pages: 240-243
- DOI
  10.1016/j.jphs.2015.09.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25253012, KAKENHI-PROJECT-25860022
[Journal Article] Endoplasmic Reticulum (ER) Stress Induces Sirtuin 1 (SIRT1) Expression via the PI3K-Akt-GSK3β Signaling Pathway and Promotes Hepatocellular Injury.2015
- Author(s)
  Koga T, Suico MA, Shimasaki S, Watanabe E, Kai Y, Koyama K, Omachi K, Morino-Koga S, Sato T, Shuto T, Mori K, Hino S, Nakao M, Kai H.
- Journal Title
  
  J Biol Chem.
  
  Volume: 290 Issue: 51 Pages: 30366-30374
- DOI
  10.1074/jbc.m115.664169
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460098, KAKENHI-PROJECT-15K19032, KAKENHI-PROJECT-25253012, KAKENHI-PROJECT-25430178, KAKENHI-PROJECT-25460102
[Journal Article] COMMD1/Murr1 reinforces HIV-1 latent infection through IκB-α stabilization.2015
- Author(s)
  Taura M, Kudo E, Kariya R, Goto H, Matsuda K, Hattori S, Vaeteewoottacharn K, McDonald F, Suico MA, Shuto T, Kai H, Okada S.
- Journal Title
  
  Journal of Virology
  
  Volume: 89(5) Issue: 5 Pages: 2643-58
- DOI
  10.1128/jvi.03105-14
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-12J08328, KAKENHI-PROJECT-14J01801, KAKENHI-PROJECT-26460098
[Journal Article] Mild Electrical Stimulation Increases Stress Resistance and Suppresses Fat Accumulation via Activation of LKB1-AMPK Signaling Pathway in C. elegans2014
- Author(s)
  Shingo Matsuyama, Masataka Moriuchi, Mary Ann Suico, Shuichiro Yano, Saori Morino-Koga, Tsuyoshi Shuto, Kunitoshi Yamanaka, Tatsuya Kondo, Eiichi Araki, Hirofumi Kai
- Journal Title
  
  PLOS ONE
  
  Volume: 9(12): e114690 Issue: 12 Pages: e114690-e114690
- DOI
  10.1371/journal.pone.0114690
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-14J10549, KAKENHI-PROJECT-24591336, KAKENHI-PROJECT-25670260, KAKENHI-PROJECT-26460098
[Journal Article] The transcription factor MEF/ELF4 is dually modulated by p53-MDM2 axis and MEF-MDM2 autoregulatory mechanism.2014
- Author(s)
  Suico MA, Fukuda R, Miyakita R, Koyama K, Taura M, Shuto T, Kai H.
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 289(38) Issue: 38 Pages: 26143-54
- DOI
  10.1074/jbc.m114.580209
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-12J08328, KAKENHI-PUBLICLY-25117721, KAKENHI-PROJECT-26460098
[Journal Article] Mild electrical stimulation with heat shock reduces visceral adiposity and improves metabolic abnormalities in subjects with metabolic syndrome or type 2 diabetes: Randomized crossover trials.2014
- Author(s)
  Kondo T, Ono K, Kitano S, Matsuyama R, Goto R, Suico MA, Kawasaki S, Igata M, Kawashima J, Motoshima H, Matsumura T, Kai H, Araki E
- Journal Title
  
  EBioMedicine
  
  Volume: 1 Issue: 1 Pages: 80-89
- DOI
  10.1016/j.ebiom.2014.11.001
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24591336, KAKENHI-PROJECT-25461360, KAKENHI-PROJECT-25461374, KAKENHI-PROJECT-25670260, KAKENHI-PROJECT-26460098
[Journal Article] Inhibition of post-translational N-glycosylation by HRD1 that controls the fate of ABCG5/8 transporter.2014
- Author(s)
  Suzuki S, Shuto T, Sato T, Kaneko M, Takada T, Suico MA, Cyr DM, Suzuki H, Kai H
- Journal Title
  
  Scientific reports
  
  Volume: 4 Issue: 1 Pages: 4258-4258
- DOI
  10.1038/srep04258
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23790095, KAKENHI-PROJECT-24300135, KAKENHI-PROJECT-24659068, KAKENHI-PROJECT-24790079, KAKENHI-PROJECT-25253012, KAKENHI-PROJECT-25460102, KAKENHI-PROJECT-26460099
[Journal Article] Mild electrical stimulation at 0.1-ms pulse width induces p53 protein phosphorylation and G2 arrest in human epithelial cells.2013
- Author(s)
  Fukuda ft, Suico MA, Koyama K, Omachi K, Kai Y, Matsuyama S, Mitsutake K, Taura M, Mo rino-Koga S, Shuto T, Kai H.
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 288(22) Issue: 22 Pages: 16117-16126
- DOI
  10.1074/jbc.m112.442442
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J08328, KAKENHI-PROJECT-13J08535, KAKENHI-PROJECT-23590082, KAKENHI-PUBLICLY-25117721, KAKENHI-PROJECT-25253012, KAKENHI-PROJECT-25460102, KAKENHI-PROJECT-25670260
[Journal Article] Diethyldithiocarbamate induces apoptosis in HHV-8-infected primary effusion lymphoma cells via inhibition of the NF-κB pathway2012
- Author(s)
  Matsuno T, Kariya R, Yano S, Morino-Koga S, Taura M, Suico MA, Shimauchi y Matsuyama S, Okamoto Y, Shuto T, Kai H, Okada S
- Journal Title
  
  Int J Oncol
  
  Volume: 40(4) Pages: 1071-1078
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390015
[Journal Article] Rb/E2F1 Regulates the Innate Immune Receptor Toll-Like Receptor 3 in Epithelial Cells.2012
- Author(s)
  Taura M, Suico MA, Koyama K, Komatsu K, Miyakita R, Matsumoto C, Kudo E, Kariya R, Goto H, Kitajima S, Takahashi C, Shuto T, Nakao M, Okada S, Kai H.
- Journal Title
  
  Mol Cell Biol.
  
  Volume: 32(8) Pages: 1581-1590
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590082
[Journal Article] Diethyldithiocarbamate induces apoptosis in HHV-8-infected primary effusion lymphoma cells via inhibition of the NF-κB pathway.2012
- Author(s)
  Matsuno T, Kariya R, Yano S, Morino-Koga S, Taura M, Suico MA, Shimauchi Y, Matsuyama S, Okamoto Y, Shuto T, Kai H, Okada S.
- Journal Title
  
  Int J Oncol.
  
  Volume: 40(4) Pages: 1071-1078
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590082
[Journal Article] SynergismBetween Interleukin (IL)-17 and Toll-likeReceptor 2 and 4 Signals to Induce IL-8Expression in Cystic Fibrosis AirwayEpithelial Cells2012
- Author(s)
  Mizunoe S, Shuto T, Suzuki S, MatsumotoC, Watanabe K, Ueno-Shuto K, Suico MA,Onuki K, Gruenert DC, Kai H
- Journal Title
  
  J. Pharmacol. Sci
  
  Volume: 118 Pages: 512-520
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390015
[Journal Article] Rb/E2F1 regulates the innate immune receptor Toll-like receptor 3 in epithelial cells2012
- Author(s)
  Taura M., et.al.
- Journal Title
  
  Molecular and Cellular Biology
  
  Volume: 32(8) Issue: 8 Pages: 1581-1590
- DOI
  10.1128/mcb.06454-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J08328, KAKENHI-PROJECT-22390015, KAKENHI-PROJECT-22390055, KAKENHI-PROJECT-23590082, KAKENHI-PROJECT-23701048, KAKENHI-PUBLICLY-23107725, KAKENHI-PLANNED-23116009
[Journal Article] Rb/E2F1 Regulates the Innate Immune Receptor Toll-Like Receptor 3 in Epithelial Cells2012
- Author(s)
  Taura M, Suico MA, Koyama K, Komatsu K, Miyakita R, Matsumoto C, Kudo E, Kariya R, Goto H, Kitajima S, Takahashi C, Shuto T, Nakao M, Okada s, Kai H
- Journal Title
  
  Mol Cell Biol
  
  Volume: 32(8) Pages: 1581-1590
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390015
[Journal Article] Synergism Between Interleukin (IL)-17 and Toll-like Receptor 2 and 4 Signals to Induce IL-8 Expression in Cystic Fibrosis Airway Epithelial Cells2012
- Author(s)
  Mizunoe S, Shuto T, Suzuki S, Matsumoto C, Watanabe K, Ueno-Shuto K, Suico MA, Onuki K, Gruenert DC, Kai H
- Journal Title
  
  J Pharmacol Sci
  
  Volume: (印刷中)
- NAID
  10030572169
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390015
[Journal Article] STT3B-dependent posttranslationalN-glycosylation as a novel surveillancesystem for secretory protein2012
- Author(s)
  Sato T, Sako Y, Sho M, Momohara M, SuicoMA, Shuto T, Nishitoh H, Okiyoneda T,Kokame K, Kaneko M, Taura M, Miyata M,Chosa K, Koga T, Koga SM, Wada I, Kai H
- Journal Title
  
  Mol. Cell
  
  Volume: 47 Pages: 99-110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390015
[Journal Article] Synergism Between Interleukin (IL)-17 and Toll-like Receptor 2 and 4 Signals to Induce IL-8 Expression in Cystic Fibrosis Airway Epithelial Cells.2012
- Author(s)
  Mizunoe S, Shuto T, Suzuki S, Matsumoto C, Watanabe K, Ueno-Shuto K, Suico MA, Onuki K, Gruenert DC, Kai H.
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590082
[Journal Article] Hyperthermia With Mild Electrical Stimulation Protects Pancreatic β-Cells From Cell Stresses and Apoptosis.2012
- Author(s)
  Kondo T, Sasaki K, Matsuyama R, Morino-Koga S, Adachi H, Suico MA, Kawashima J, Motoshima H, Furukawa N, Kai H, Araki E.
- Journal Title
  
  Diabetes.
  
  Volume: 61(4) Pages: 838-847
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590082
[Journal Article] Rb/E2F1 Regulatesthe Innate Immune Receptor Toll-LikeReceptor 3 in Epithelial Cells2012
- Author(s)
  Taura M, Suico MA, Koyama K, Komatsu K,Miyakita R, Matsumoto C, Kudo E, Kariya R,Goto H, Kitajima S, Takahashi C, Shuto T,Nakao M, Okada S, Kai H
- Journal Title
  
  Mol. Cell.Biol
  
  Volume: 32 Pages: 1581-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390015
[Journal Article] Hyperthermia With Mild Electrical Stimulation Protects Pancreatic β-Cells From Cell Stresses and Apoptosis2012
- Author(s)
  Kondo T, Sasaki K, Matsuyama R, Morino-Koga S, Adachi H, Suico MA, Kawashima J, Motoshima H, Furukawa N, Kai H, Araki E
- Journal Title
  
  Diabetes
  
  Volume: 61(4) Pages: 838-847
- NAID
  120005368280
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390015
[Journal Article] Lucidenic acids-rich extract from antlered form of Ganoderma lucidum enhances TNF α induction in THP-1 monocytic cells possibly via its modulation of MAP kinases p38 and JNK2011
- Author(s)
  Watanabe K, Shuto T, Sato M, Onuki K, Mizunoe S, Suzuki S, Sato T, Koga T, Suico MA, Kai H, Ikeda T
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 408(1) Pages: 18-24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390015
[Journal Article] CFTR-deficiency renders mice highlysusceptible to cutaneous symptoms duringmite infestation2011
- Author(s)
  Hashimoto Y, Shuto T, Mizunoe S, TomitaA, Koga T, Sato T, Takeya M, Suico MA,Niibori A, Sugahara T, Shimasaki S,Sugiyama T, Scholte B, Kai H
- Journal Title
  
  Lab Invest
  
  Volume: 91(4) Pages: 509-18
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390015
[Journal Article] Posttranslational negative regulation of glycosylated and non-glycosylated BCRP expression by Derlin-12011
- Author(s)
  Sugiyama T, Shuto T, Suzuki S, Sato T, Koga T, Suico MA, Kusuhara H, Sugiyama Y, Cyr DM, Kai H
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 404(3) Pages: 853-858
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390015
[Journal Article] CFTR-deficiency renders mice highly susceptible to cutaneous symptoms during mite infestation2011
- Author(s)
  Hashimoto Y, Shuto T, Mizunoe S, Tomita A, Koga T, Sato T, Takeya M, Suico MA, Niibori A, Sugahara T, Shimasaki S, Sugiyama T, Scholte B, Kai H
- Journal Title
  
  Lab Invest
  
  Volume: 91(4) Pages: 509-518
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390015
[Journal Article] MEF/ELF4 transactivation by E2F1 is inhibited by p532011
- Author(s)
  Taura M, Suico MA, Fukuda R, Koga T, Shuto T, Sato T, Morino-Koga S, Okada S, Kai H
- Journal Title
  
  Nucleic Acids Res
  
  Volume: 39 Issue: 1 Pages: 76-88
- DOI
  10.1093/nar/gkq762
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590082
[Journal Article] Glucose Uptake in Rat Skeletal Muscle L6 Cells Is Increased by Low-Intensity Electrical Current Through the Activation of the Phosphatidylinositol-3-OH kinase (PI-3K) / Akt Pathway.2011
- Author(s)
  Yano S, Morino-Koga S, Kondo T, Suico MA, Koga T, Shimauchi Y, Matsuyama S, Shuto T, Sato T, Araki E, Kai H.
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: 115(1) Pages: 94-98
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590082
[Journal Article] Posttranslational negativeregulation of glycosylated andnon-glycosylated BCRP expression byDerlin-12011
- Author(s)
  Sugiyama T, Shuto T, Suzuki S, Sato T,Koga T, Suico MA, Kusuhara H, Sugiyama Y,Cyr DM, Kai H
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 404(3) Pages: 853-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390015
[Journal Article] MEF/ELF4 transactivation by E2F1 isinhibited by p532011
- Author(s)
  Taura M, Suico MA, Fukuda R, Koga T,Shuto T, Sato T, Morino-Koga S, Okada S, KaiH
- Journal Title
  
  Nucleic Acids Res
  
  Volume: 39(1) Pages: 76-88
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390015
[Journal Article] Curcumindecreases toll-like receptor-2 geneexpression and function in human monocytesand neutrophils2010
- Author(s)
  Shuto T, Ono T, Ohira Y, Shimasaki S,Mizunoe S, Watanabe K, Suico MA, Koga T,Sato T, Morino S, Sato K, Kai H
- Journal Title
  
  Biochem Biophys ResCommun
  
  Volume: 398(4) Pages: 647-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390015
[Journal Article] Role of the glutamic acid 54 residue in transthyretin stability and thyroxine binding2010
- Author(s)
  Miyata M, Sato T, Mizuguchi M, Nakamura T, Ikemizu S, Nabeshima Y, Susuki S, Suwa Y, Morioka H, Ando Y, Suico MA, Shuto T, Koga T, Yamagata Y, Kai H
- Journal Title
  
  Biochemistry 49
  
  Pages: 114-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390045
[Journal Article] Modified Mild Heat Shock Modality Attenuates Hepatic Ischemia/Reperfusion Injury2010
- Author(s)
  Mariko Oba, Mary Ann Suico, Saori Morino, Shuichiro Yano, Takashi Matsuno, Tomoaki Koga, Takashi Sato, Tsuyoshi Shuto, Hirofumi Kai
- Journal Title
  
  J. Surg. Res. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790068
[Journal Article] TLR3 induction by anticancer drugspotentiates poly I:C-induced tumor cellapoptosis2010
- Author(s)
  Taura M, Fukuda R, Suico MA, Eguma A,Koga T, Shuto T, Sato T, Morino-Koga S, KaiH
- Journal Title
  
  Cancer Sci
  
  Volume: 101(7) Pages: 1610-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390015
[Journal Article] Role of the glutamic acid 54 residue in transthyretin stability and thyroxine binding2010
- Author(s)
  Miyata M, Sato T, Mizuguchi M, Nakamura T, Ikemizu S, Nabeshima Y, Susuki S, Suwa Y, Morioka H, Ando Y, Suico MA, Shuto T, Koga T, Yamagata Y, Kai H.
- Journal Title
  
  Biochemistry 49
  
  Pages: 114-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790068
[Journal Article] TLR3 induction by anticancer drugs potentiates poly I:C-induced tumor cell apoptosis2010
- Author(s)
  Manabu Taura, R. Fukuda, Mary Ann Suico, Ayaka Eguma, Tomoaki Koga, Tsuyoshi Shuto, Takashi Sato, Saori Koga Morino, Hirofumi Kai
- Journal Title
  
  Cancer Sci (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790068
[Journal Article] Role of theglutamic acid 54 residue in transthyretin stability and thyroxine binding2010
- Author(s)
  Miyata M, Sato T, Mizuguchi M, NakamuraT, Ikemizu S, Nabeshima Y, Susuki S, SuwaY, Morioka H, Ando Y, Suico MA, Shuto T,Koga T, Yamagata Y, and Kai H
- Journal Title
  
  Biochemistry
  
  Volume: 49 Pages: 114-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390015
[Journal Article] TLR3 induction by anticancer drugs potentiates poly I:C-induced tumor cell apoptosis2010
- Author(s)
  Manabu Taura, R. Fukuda, Mary Ann Suico, Ayaka Eguma, Tomoaki Koga, Tsuyoshi Shuto, Takashi Sato, Saori Koga Morino, Hirofumi Kai
- Journal Title
  
  Cancer Sci (in press)
- NAID
  10026594490
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390045
[Journal Article] Crystal structure of green teapolyphenol(-)-epigallocatechin gallate(EGCG)-transthyretin complex revealsnovel binding site distinct fromthyroxine binding site2010
- Author(s)
  Miyata M, Sato T, Kugimiya M, Sho M,Nakamura T, Ikemizu S, Chirifu M,Mizuguchi M, Nabeshima Y, Suwa Y, MoriokaH, Arimori T, Suico MA, Shuto T, Sako Y,Momohara M, Koga T, Morino-Koga S, YamagataY, Kai H
- Journal Title
  
  Biochemistry
  
  Volume: 49 Pages: 6104-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390015
[Journal Article] Modified Mild Heat Shock Modality Attenuates Hepatic Ischemia/Reperfusion Injury2010
- Author(s)
  Mariko Oba, Mary Ann Suico, Saori Morino, Shuichiro Yano, Takashi Matsuno, Tomoaki Koga, Takashi Sato, Tsuyoshi Shuto, Hirofumi Kai
- Journal Title
  
  J. Surg. Res (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390045
[Journal Article] Endoplasmicreticulum stress increases the expressionand function of toll-like receptor-2 inepithelial cells2010
- Author(s)
  Shimasaki S, Koga T, Shuto T, Suico MA,Sato T, Watanabe K, Morino-Koga S, TauraM, Okada S, Mori K and Kai H
- Journal Title
  
  Biochem Biophys ResCommun
  
  Volume: 402(2) Pages: 235-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390015
[Journal Article] Calreticulin positively regulates the expression and function of epithelial sodium channel2009
- Author(s)
  Takuya Sugahara, Tomoaki Koga, Keiko Ueno-Shuto, Tsuyoshi Shuto, Eriko Watanabe, Maekawa A., Kitamura K., Tomita K., Ai Mizuno, Takashi Sato, Mary Ann Suico, Hirofumi Kai
- Journal Title
  
  Exp. Cell Res. 315
  
  Pages: 3294-300
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790068
[Journal Article] Calreticulin positively regulates the expression and function of epithelial sodium channel2009
- Author(s)
  Takuya Sugahara, Tomoaki Koga, Keiko Ueno-Shuto, Tsuyoshi Shuto, Eriko Watanabe, Maekawa A., Kitamura K., Tomita K., Ai Mizuno, Takashi Sato, Mary Ann Suico, Hirofumi Kai
- Journal Title
  
  Exp. Cell Res 315
  
  Pages: 3294-300
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390045
[Journal Article] The endoplasmic reticulum-associated degradation of transthyretin variants is negatively regulated by BiP in mammalian cells2009
- Author(s)
  Susuki S, Sato T, Miyata M, Momohara M, Suico MA, Shuto T, Ando Y, Kai H
- Journal Title
  
  J Biol Chem 284
  
  Pages: 8312-8321
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390045
[Journal Article] The expression of antimicrobial peptide lysozyme is increased by treatment2009
- Author(s)
  Mary Ann Suico, Atsushi Tanaka, Tsuyoshi Shuto, Hirofumi Kai
- Journal Title
  
  J. Health Sci. 55
  
  Pages: 456-462
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790068
[Journal Article] The expression of antimicrobial peptide lysozyme is increased by treatment with silver nanoparticle (Atomyball SR) in mammalian epithelial cells2009
- Author(s)
  Mary Ann Suico, Atsushi Tanaka, Tsuyoshi Shuto, Hirofumi Kai
- Journal Title
  
  J. Health Sci 55
  
  Pages: 456-462
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390045
[Journal Article] The endoplasmic reticulum-associated degradation of transthyretin variants is negatively regulated by BiP in mammalian cells2009
- Author(s)
  Susuki S, Sato T, Miyata M, Momohara M, Suico MA, Shuto T, Ando Y, Kai H.
- Journal Title
  
  J Biol Chem. 284
  
  Pages: 8312-8321
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790068
[Journal Article] A novel combination of mild electrical stimulation and hyperthermia: general concepts and applications (review)2009
- Author(s)
  Hirofumi Kai, Mary Ann Suico, Saori Morino, Tatsuya Kondo, Mariko Oba, Mikiko Noguchi, Tsuyoshi Shuto, Eiichi Araki
- Journal Title
  
  Int. J. Hyperthermia 25
  
  Pages: 655-660
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390045
[Journal Article] A novel combination of mild electrical stimulation and hyperthermia: general concepts and applications (review)2009
- Author(s)
  Hirofumi Kai, Mary Ann Suico, Saori Morino, Tatsuya Kondo, Mariko Oba, Mikiko Noguchi, Tsuyoshi Shuto, Eiichi Araki
- Journal Title
  
  Int. J. Hyperthermia 25
  
  Pages: 655-660
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790068
[Journal Article] Interferon-gamma down-regulated Hsp27 and enhances hyperthermia-induced tumor cell death in vitro and tumor suppression in vivo2008
- Author(s)
  Oba M., Yano S., Shuto T., Suico M.A., Eguma A., Kai H.
- Journal Title
  
  Int. J. Oncol. 32
  
  Pages: 1317-1324
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790068
[Journal Article] Mild Electrical Stimulation with heat shock ameliorates insulin resistance via enhanced insulin signaling. Increases Ubiquitinated Proteins and Hsp72 in A549 Cells via Attenuation of Proteasomal Degradation2008
- Author(s)
  Saori Morino, Tatsuya Kondo, Kazunari Sasaki, Hironori Adachi, Mary Ann Suico, Erika Sekimoto, Tomoko Matsuda, Tsuyoshi Shuto, Eiichi Araki, Hirofumi Kai
- Journal Title
  
  PLoS ONE 3(12)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390045
[Journal Article] Interferon-gamma down-regulated Hsp27 and enhances hyperthermia-induced tumor cell death in vitro and tumor suppression in vivo2008
- Author(s)
  Oba M., Yano S., Shuto T., Suico M.A., Eguma A., Kai H
- Journal Title
  
  Int. J. Oncol 32
  
  Pages: 1317-1324
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390045
[Journal Article] Mild Electrical Stimulation with heat shock ameliorates insulin resistance via enhanced insulin signaling. Increases Ubiquitinated Proteins and Hsp72 in A549 Cells via Attenuation of Proteasomal Degradation2008
- Author(s)
  Saori Morino, Tatsuya Kondo, Kazunari Sasaki, Hironori Adachi, Mary Ann Suico, Erika Sekimoto, Tomoko Matsuda, Tsuyoshi Shuto, Eiichi Araki, Hirofumi Kai.
- Journal Title
  
  PLoS ONE 3(12)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790068
[Journal Article] Role of calnexin in the ER quality control and productive folding of CFTR; differential effect of calnexin knockout on wild-type and DF508 CFTR. Biochem2008
- Author(s)
  Okiyoneda T., Niibori A., Harada K., Kohno T., Michalak M., Duszyk M., Wada I., Ikawa M., Shuto T., Suico M. A, Kai H.
- Journal Title
  
  Biochim. Acta (Mol. Cell Res. ) 1783
  
  Pages: 1585-94
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790068
[Journal Article] p53 regulates TLR3 expression and function in human epithelial cell lines2008
- Author(s)
  Manabu Taura, Ayaka Eguma, Mary Ann Suico, Tsuyoshi Shuto, Tomoaki Koga, Kensei Komatsu, Takefumi Komune, Takashi Sato, Hideyuki Saya, Jian-Dong Li, Hirofumi Kai
- Journal Title
  
  Mol. Cell. Biol. 28
  
  Pages: 6557-67
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790068
[Journal Article] p53 regulates TLR3 expression and function in human epithelial cell lines2008
- Author(s)
  Manabu Taura, Ayaka Eguma, Mary Ann Suico, Tsuyoshi Shuto, Tomoaki Koga, Kensei Komatsu, Takefumi Komune, Takashi Sato, Hideyuki Saya, Jian-Dong Li, Hirofumi Kai
- Journal Title
  
  Mol. Cell. Biol 28
  
  Pages: 6557-67
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390045
[Journal Article] Mild Electrical Stimulation Increases Ubiquitinated Proteins and Hsp72 in A549 Cells via Attenuation of Proteasomal Degredation2008
- Author(s)
  Saori Morino, Mary Ann Suico, Tatsuya Kondo, Erika Sekimoto, Shuichiro Yano. Tomoko Matsuda, Takashi Matsuno, Tsuyoshi Shuto, Eiichi Araki, Hirohumi Kai
- Journal Title
  
  J Pharmacol Sci 108
  
  Pages: 222-226
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390045
[Journal Article] Multi-elemental analysis of serum and amyloid fibrils in familial amyloid polyneuropathy patients2008
- Author(s)
  Susuki S., Ando Y., Sato T., Nishiyama M., Miyata M., Suico MA., Shuto T., Kai H.
- Journal Title
  
  Amyloid (The Journal of Protein Folding Disorders) 15
  
  Pages: 108-116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790068
[Journal Article] Phosphatidic acid metabolism regulate the intracellular trafficking and retrotranslocation of cystic fibrosis transmembrane conductance regulator. Biochem2008
- Author(s)
  Yasuaki Hashimoto, Tsukasa Okiyoneda, Kazutsune Harada, Keiko Ueno, Takuya Sugahara, Atsushi Yamashita, Tsuyoshi Shuto, Mary Ann Suico, Hirofumi Kai
- Journal Title
  
  Biochim. Acta (Mol. Cell Res. ) 1783
  
  Pages: 153-162
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390045
[Journal Article] DNA demethylation-dependent enhancement of toll-like receptor-2 gene expression in cystic fibrosis epithelial cells involves SP1-activated transcription2008
- Author(s)
  Takashi Furuta, Tsuyoshi Shuto, Shogo Shimasaki, Yuko Ohira, Mary Ann Suico, Dieter C Gruenert, Hirofumi Kai
- Journal Title
  
  BMC Mol Biol. 9
  
  Pages: 39-39
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790068
[Journal Article] Role of calnexin in the ER quality control and productive folding of CFTR; differential effect of calnexin knockout on wild-type and DF508 CFTR2008
- Author(s)
  Okiyoneda T., Niibori A., Harada K., Kohno T., Michalak M., Duszyk M., Wada I., Ikawa M., Shuto T., Suico M. A, Kai H
- Journal Title
  
  Biochem. Biochim. Acta (Mol. Cell Res. ) 1783
  
  Pages: 1585-94
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390045
[Journal Article] and Hirofumi Kai Phosphatidic acid metabolism regulate the intracellular trafficking and retrotranslocation of cystic fibrosis transmembrane conductance regulator2008
- Author(s)
  Yasuaki Hashimoto, Tsukasa Okiyoneda, Kazutsune Harada, Keiko Ueno, Takuya Sugahara, Atsushi Yamashita, Tsuyoshi Shuto, Mary Ann Suico
- Journal Title
  
  Biochem. Biochim. Acta (Mol. Cell Res. ) 1783
  
  Pages: 153-162
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790068
[Journal Article] DNA demethylation-dependent enhancement of toll-like receptor-2 gene expression in cystic fibrosis epithelial cells involves SP1-activated transcription2008
- Author(s)
  Takashi Furuta, Tsuyoshi Shuto, Shogo Shimasaki, Yuko Ohira, Mary Ann Suico, Dieter C Gruenert, Hirofumi Kai
- Journal Title
  
  BMC Mol Biol 9
  
  Pages: 39-39
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390045
[Journal Article] Mild Electrical Stimulation Increases Ubiquitinated Proteins and Hsp72 in A549 Cells via Attenuation of Proteasomal Degredation2008
- Author(s)
  Saori Morino, Mary Ann Suico, Tatsuya Kondo, Erika Sekimoto, Shuichiro Yano. Tomoko Matsuda, Takashi Matsuno, Tsuyoshi Shuto, Eiichi Araki, Hirohumi Kai
- Journal Title
  
  J Pharmacol Sci. 108
  
  Pages: 222-226
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790068
[Journal Article] Multi-elemental analysis of serum and amyloid fibrils in familial amyloid polyneuropathy patients2008
- Author(s)
  Susuki S., Ando Y., Sato T., Nishiyama M., Miyata M., Suico MA., Shuto T., Kai H
- Journal Title
  
  Amyloid (The Journal of Protein Folding Disorders) 15
  
  Pages: 108-116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390045
[Journal Article] Curucumin enhances cystic fibrosis transmembrane regulator expression by down-regulating calreticulin, Biochem2007
- Author(s)
  Kazutsune Harada, Tsukasa Okiyoneda, Yasuaki Hashimoto, Kimiko Oyokawa, Kimitoshi Nakamura, Mary Ann Suico, Tsuyoshi Shuto, Hirofumi Kai
- Journal Title
  
  Biophys. Res. Commun 353
  
  Pages: 351-356
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390045
[Journal Article] Increased responsiveness to TLR2 and TLR4 ligands during dimethylsulfoxideinduced neutrophil-like differentiation of HL-60 myeloid leukemia cells2007
- Author(s)
  Tsuyoshi Shuto, Takashi Furuta, Judy Cheung, Dieter C. Gruenert, Yuko Ohira, Shogo Shimasaki, Mary Ann Suico, Keizo Sato, Hirofumi Kai
- Journal Title
  
  Leuk Res 31
  
  Pages: 1721-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390045
[Journal Article] SUMO down-regulates the activity of Elf4/Myeloid Elf-1-like factor.2006
- Author(s)
  Suico M.A.et al.
- Journal Title
  
  Biochem. Biophys. Res. Commun 348
  
  Pages: 880-888
- Data Source
  KAKENHI-PROJECT-17790068
[Journal Article] Chromium (III) ion and thyroxine cooperate to stabilize the transthyretin tetramer and suppress in vitro amyloid fibril formation.2006
- Author(s)
  Sato, T., Ando, Y., Susuki, S., Mikami, F., Ikemizu, S., Nakamura, M., Suhr, O., Anraku, M., Kai, T., Suico.M.A., Shuto, T., Mizuguchi, M., Yamagata, Y., Kai, H.
- Journal Title
  
  FEBS Letters 580
  
  Pages: 491-496
- NAID
  120005499991
- Data Source
  KAKENHI-PROJECT-18054025
[Journal Article] Chromium(III) ion and thyroxine cooperate to stabilize the transthyretin tetramer and suppress in vitro amyloid fibril formation.2006
- Author(s)
  Sato T, Ando Y, Susuki S, Mikami F, Ikemizu S, Nakamura M, Suhr O, Anraku M, Kai T, Suico MA, Shuto T, Mizuguchi M, Yamagata Y, Kai H.
- Journal Title
  
  FEBS Lett. 580(2)
  
  Pages: 491-496
- Data Source
  KAKENHI-PROJECT-17790068
[Journal Article] Promoter hypomethylation of Toll-like receptor-2 gene is associated with increased proinflammatory response toward bacterial peptidoglycan in cystic fibrosis bronchial epithelial cells.2006
- Author(s)
  Shuto T, Furuta T, Oba M, Xu H, Li JD, Cheung J, Gruenert DC, Uehara A, Suico MA, Okiyoneda T, Kai H.
- Journal Title
  
  FASEB J. 20(6)
- Data Source
  KAKENHI-PROJECT-17790068
[Journal Article] Sp1-dependent regulation of Myeloid Elf-1 like factor in human epithelial cells.2005
- Author(s)
  Koga T, Suico MA, Nakamura H, Taura M, Lu Z, Shuto T, Okiyoneda T, Kai H.
- Journal Title
  
  FEBS Lett. 579(13)
  
  Pages: 2811-2816
- Data Source
  KAKENHI-PROJECT-17790068
[Journal Article] Membrane-anchored CD14 is required for LPS-induced TLR4 endocytosis in TLR4/MD-2/CD14 overexpressing CHO cells.2005
- Author(s)
  Shuto T, Kato K, Mori Y, Viriyakosol S, Oba M, Furuta T, Okiyoneda T, Arima H. Suico MA, Kai H.
- Journal Title
  
  Biochem Biophys Res Commun. 338(3)
  
  Pages: 1402-1409
- Data Source
  KAKENHI-PROJECT-17790068
[Journal Article] Vitamins K1 and K2 potentiate hyperthermia by down-regulating Hsp72 expression in vitro and in vivo.2005
- Author(s)
  Shimohara S, Murakami T, Morikawa M, Matsuo J, Nagayama S, Shuto T, Suico MA, Okiyoneda T, Yamatsu I, Mizushima T, Shimasaki T, Kai H.
- Journal Title
  
  Int J Oncol. 27(6)
  
  Pages: 1527-1533
- Data Source
  KAKENHI-PROJECT-17790068
[Journal Article] Hyperthermia suppresses the cytotoxicity of NK cells via down-regulation of perforin/granzyme B expression.2005
- Author(s)
  Koga T, Harada H, Shi TS, Okada S, Suico MA, Shuto T, Kai H.
- Journal Title
  
  Biochem Biophys Res Commun. 337(4)
  
  Pages: 1319-1323
- Data Source
  KAKENHI-PROJECT-17790068
[Journal Article] Endoplasmic reticulum quality control regulates the fate of transthyretin variants in the cell
- Author(s)
  Takashi Sato, Seiko Susuki, Mary Ann Suico, Masanori Miyata, Yukio Ando, Mineyuki Mizuguchi, Makoto Takeuchi, Mizuki Dobashi, Tsuyoshi Shuto, Hirofumi Kai
- Journal Title
  
  EMBO J 26
  
  Pages: 2501-2512
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390045
[Patent] 難治性遺伝性腎疾患アルポート症候群の根治療法のための薬剤2020
- Inventor(s)
  甲斐,首藤,メリーアン,塚本,三隅,河原,人羅,加藤,小谷,荒木
- Industrial Property Rights Holder
  甲斐,首藤,メリーアン,塚本,三隅,河原,人羅,加藤,小谷,荒木
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-20K07086
[Patent] 難治性遺伝性腎疾患アルポート症候群の根治療法のための薬剤2020
- Inventor(s)
  甲斐,首藤,メリーアン,塚本,三隅,河原,人羅,加藤,小谷,荒木
- Industrial Property Rights Holder
  甲斐,首藤,メリーアン,塚本,三隅,河原,人羅,加藤,小谷,荒木
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-19H03379
[Presentation] CyclosporinA derivative as therapeutic candidate for Alport syndrome by inducing mutant type IV collagen secretion2023
- Author(s)
  Mary Ann Suico
- Organizer
  第46回日本分子生物学会年会2023
- Data Source
  KAKENHI-PROJECT-23K06165
[Presentation] AKI to CKD transitionモデルマウスに対する微弱パルス電流と温熱の同時印加の効果2022
- Author(s)
  津波古遥希、寺本啓祐、加世田将大、Piruzyan Mariam、岩上長巨、荒川知南、Mary Ann Suico、首藤剛、甲斐広文
- Organizer
  第75回日本薬理学会西南部会 (2022.10.01　高知県民文化ホール(高知))
- Data Source
  KAKENHI-PROJECT-23K24072
[Presentation] AKI to CKD transition モデルマウスに対する微弱パルス電流と温熱の同時印加の効果2022
- Author(s)
  津波古遥希、寺本啓祐、加世田将大、Piruzyan Mariam、岩上長巨、荒川知南、Marry Ann Suico、首藤剛、甲斐広文
- Organizer
  第39回日本薬学会九州山口支部大会 (2022.10.19-20　長崎国際大学(長崎))
- Data Source
  KAKENHI-PROJECT-23K24072
[Presentation] Efficacy of Keap1-Nrf2 protein-protein interaction inhibitor for progressive phenotype in Alport syndrome mouse model2022
- Author(s)
  Shota Kaseda, Yuya Sannomiya, Jun Horizono, Jun Kuwazuru, Sayaka Ogi, Ryoko Sasaki, Hidetoshi Sunamoto, Hirohiko Fukiya, Hayato Nishiyama, Misato Kamura, Saki Niinou, Mary Ann Suico, Futoshi Nara, Tsuyoshi Shuto, Kazuhiro Onuma, Hirofumi Kai
- Organizer
  第57回日本小児腎臓病学会学術集会（2022.05.27-28 沖縄コンベンションセンター(沖縄)）
- Data Source
  KAKENHI-PROJECT-20K07086
[Presentation] NanoLuciferase 技術を用いた HTS 評価系による新規 Alport 症候群治療薬候補化合物の同定2022
- Author(s)
  桑水流淳、加世田将大、三宮裕也、堀園潤、津波古遥希、小山結実、尾脇あいみ、佐藤諒一、白神正博、Mary Ann Suico、首藤剛、甲斐広文
- Organizer
  第16回次世代を担う若手のための医療薬科学シンポジウム (2022.10.29-30　和歌山県立医科大学(和歌山))
- Data Source
  KAKENHI-PROJECT-20K07086
[Presentation] 可逆的 Keap1 阻害薬による慢性腎臓病モデルマウスの病態改善効果2022
- Author(s)
  堀園潤、加世田将大、三宮裕也、桑水流淳、小木彩矢佳、佐々木亮子、砂本秀利、吹屋洋彦、西山勇人、小山結実、 Mary Ann Suico、奈良太、首藤剛、大沼和弘、甲斐広文
- Organizer
  第75回日本薬理学会西南部会 (2022.10.01　高知県民文化ホール(高知))
- Data Source
  KAKENHI-PROJECT-23K24072
[Presentation] NanoLuciferase 技術を用いた HTS 評価系による新規 Alport 症候群治療薬候補化合物の同定2022
- Author(s)
  桑水流淳、加世田将大、三宮裕也、堀園潤、津波古遥希、小山結実、尾脇あいみ、佐藤諒一、白神正博、Mary Ann Suico、首藤剛、甲斐広文
- Organizer
  第16回次世代を担う若手のための医療薬科学シンポジウム (2022.10.29-30　和歌山県立医科大学(和歌山))
- Data Source
  KAKENHI-PROJECT-23K24072
[Presentation] 新規Keap1阻害薬の慢性腎臓病に対する病態改善効果2022
- Author(s)
  堀園潤、加世田将大、三宮裕也、桑水流淳、小木彩矢佳、佐々木亮子、砂本秀利、吹屋洋彦、西山勇人、小山結実、Mary Ann Suico、奈良太、首藤剛、大沼和弘、甲斐広文
- Organizer
  次世代を担う若手のための創薬・医療薬理シンポジウム2022 (2022.08.27 静岡県立大学(静岡))
- Data Source
  KAKENHI-PROJECT-20K07086
[Presentation] Efficacy of Keap1-Nrf2 protein-protein interaction inhibitor for progressive phenotype in Alport syndrome mouse model2022
- Author(s)
  Shota Kaseda, Yuya Sannomiya, Jun Horizono, Jun Kuwazuru, Sayaka Ogi, Ryoko Sasaki, Hidetoshi Sunamoto, Hirohiko Fukiya, Hayato Nishiyama, Misato Kamura, Saki Niinou, Mary Ann Suico, Futoshi Nara, Tsuyoshi Shuto, Kazuhiro Onuma, Hirofumi Kai
- Organizer
  第57回日本小児腎臓病学会学術集会（2022.05.27-28 沖縄コンベンションセンター(沖縄)）
- Data Source
  KAKENHI-PROJECT-23K24072
[Presentation] 糸球体障害を呈する慢性腎臓病モデルマウスに対する Keep1-Nrf2 タンパク質間相互作用阻害薬の有効性2022
- Author(s)
  加世田将大、三宮裕也、堀園潤、桑水流淳、Mary Ann Suico、小木彩矢佳、佐々木亮子、砂本秀利、吹屋洋彦、西山勇人、嘉村美里、奈良太、首藤剛、大沼和弘、甲斐広文
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20K07086
[Presentation] 遺伝性腎疾患Alport症候群におけるコラーゲン受容体DDR2の阻害による腎病態への影響についての基礎的検討2022
- Author(s)
  三宮裕也、加世田将大、嘉村美里、桑水流淳、Suico Mary Ann、首藤剛、甲斐広文
- Organizer
  日本薬学会第142回年会　オンライン学会
- Data Source
  KAKENHI-PROJECT-19H03379
[Presentation] 可逆的 Keap1 阻害薬による慢性腎臓病モデルマウスの病態改善効果2022
- Author(s)
  堀園潤、加世田将大、三宮裕也、桑水流淳、小木彩矢佳、佐々木亮子、砂本秀利、吹屋洋彦、西山勇人、小山結実、 Mary Ann Suico、奈良太、首藤剛、大沼和弘、甲斐広文
- Organizer
  第75回日本薬理学会西南部会 (2022.10.01　高知県民文化ホール(高知))
- Data Source
  KAKENHI-PROJECT-20K07086
[Presentation] Mild electrical stimulation and heat shock suppress acute kidney injury (AKI) to chronic kidney disease (CKD) transition2022
- Author(s)
  Haruki Tsuhako, Keisuke Teramoto, Shota Kaseda, Piruzyan Mariam, Tatsuo Iwakami, Tina Arakawa, Mary Ann Suico, Tsuyoshi Shuto, Hirofumi Kai
- Organizer
  第96回日本薬理学会年会 (2022.11.30-12.3　パシフィコ横浜 (神奈川))
- Data Source
  KAKENHI-PROJECT-23K24072
[Presentation] Renal protective effect of a novel non-covalent Keap1-Nrf2 inhibitor in chronic kidney disease2022
- Author(s)
  堀園潤、加世田将大、三宮裕也、桑水流淳、小木彩矢佳、佐々木亮子、砂本秀利、吹屋洋彦、西山勇人、小山結実、Mary Ann Suico、奈良太、首藤剛、大沼和弘、甲斐広文
- Organizer
  第16回次世代を担う若手のための医療薬科学シンポジウム (2022.10.29-30　和歌山県立医科大学(和歌山))
- Data Source
  KAKENHI-PROJECT-23K24072
[Presentation] 慢性腎臓病における Keap1-Nrf2 タンパク質間相互作用阻害薬の有用性2022
- Author(s)
  堀園潤、加世田将大、三宮裕也、桑水流淳、小木彩矢佳、佐々木亮子、砂本秀利、吹屋洋彦、西山勇人、小山結実、Mary Ann Suico、奈良太、首藤剛、大沼和弘、甲斐広文
- Organizer
  第21回・次世代を担う若手のためのファーマ・バイオフォーラム2022 (2022.09.03-04 名古屋市立大学薬学部(名古屋))
- Data Source
  KAKENHI-PROJECT-20K07086
[Presentation] 糸球体障害を呈する慢性腎臓病モデルマウスに対する Keep1-Nrf2 タンパク質間相互作用阻害薬の有効性2022
- Author(s)
  加世田将大、三宮裕也、堀園潤、桑水流淳、Mary Ann Suico、小木彩矢佳、佐々木亮子、砂本秀利、吹屋洋彦、西山勇人、嘉村美里、奈良太、首藤剛、大沼和弘、甲斐広文
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19H03379
[Presentation] 遺伝性腎疾患Alport症候群におけるコラーゲン受容体DDR2の阻害による腎病態への影響についての基礎的検討2022
- Author(s)
  三宮裕也、加世田将大、嘉村美里、桑水流淳、Suico Mary Ann、首藤剛、甲斐広文
- Organizer
  日本薬学会第142回年会　オンライン学会
- Data Source
  KAKENHI-PROJECT-20K07086
[Presentation] 新規Keap1阻害薬の慢性腎臓病に対する病態改善効果2022
- Author(s)
  堀園潤、加世田将大、三宮裕也、桑水流淳、小木彩矢佳、佐々木亮子、砂本秀利、吹屋洋彦、西山勇人、小山結実、Mary Ann Suico、奈良太、首藤剛、大沼和弘、甲斐広文
- Organizer
  次世代を担う若手のための創薬・医療薬理シンポジウム2022 (2022.08.27 静岡県立大学(静岡))
- Data Source
  KAKENHI-PROJECT-23K24072
[Presentation] 慢性腎臓病における Keap1-Nrf2 タンパク質間相互作用阻害薬の有用性2022
- Author(s)
  堀園潤、加世田将大、三宮裕也、桑水流淳、小木彩矢佳、佐々木亮子、砂本秀利、吹屋洋彦、西山勇人、小山結実、Mary Ann Suico、奈良太、首藤剛、大沼和弘、甲斐広文
- Organizer
  第21回・次世代を担う若手のためのファーマ・バイオフォーラム2022 (2022.09.03-04 名古屋市立大学薬学部(名古屋))
- Data Source
  KAKENHI-PROJECT-23K24072
[Presentation] 遺伝性糸球体腎炎 Alport 症候群モデルマウスに対する可逆的 Keap1 阻害剤の腎保護効果2021
- Author(s)
  堀園潤、加世田将大、三宮裕也、桑水流淳、小木彩矢佳、佐々木亮子、砂本秀利、吹屋洋彦、西山勇人、嘉村美里、新納咲紀、小山結実、Mary Ann Suico、奈良太、首藤剛、大沼和弘、甲斐広文
- Organizer
  第38回日本薬学会九州山口支部大会　オンライン学会
- Data Source
  KAKENHI-PROJECT-20K07086
[Presentation] The role of discoidin domain receptor 2 in the renal dysfunction of Alport syndrome mouse mode2021
- Author(s)
  Yuya Sannomiya, Shota Kaseda, Misato Kamura, Jun Kuwazuru, Saki, Niino, Tsuyoshi Shuto, Mary Ann Suico, Hirofumi Kai
- Organizer
  The 23rd Korea-Japan Joint Seminar on Pharmacology (KJJSP) Online
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03379
[Presentation] 遺伝性糸球体腎炎 Alport 症候群モデルマウスに対する可逆的 Keap1 阻害剤の腎保護効果2021
- Author(s)
  堀園潤、加世田将大、三宮裕也、桑水流淳、小木彩矢佳、佐々木亮子、砂本秀利、吹屋洋彦、西山勇人、嘉村美里、新納咲紀、小山結実、Mary Ann Suico、奈良太、首藤剛、大沼和弘、甲斐広文
- Organizer
  第38回日本薬学会九州山口支部大会　オンライン学会
- Data Source
  KAKENHI-PROJECT-19H03379
[Presentation] 可逆的Keap1阻害剤は遺伝性糸球体腎炎Alport症候群モデルマウスの腎病態を改善する2021
- Author(s)
  加世田将大、三宮裕也、桑水流淳、小木彩矢佳、佐々木亮子、砂本秀利、吹屋洋彦、西山勇人、嘉村美里、新納咲紀、堀園潤、小山結実、Suico Mary Ann、大沼和弘、奈良太、首藤剛、甲斐広文
- Organizer
  日本薬学会第141回年会　オンライン学会
- Data Source
  KAKENHI-PROJECT-19H03379
[Presentation] The role of discoidin domain receptor 2 in the renal dysfunction of Alport syndrome mouse model2021
- Author(s)
  Yuya Sannomiya, Shota Kaseda, Misato Kamura, Jun Kuwazuru, Saki, Niino, Tsuyoshi Shuto, Mary Ann Suico, Hirofumi Kai
- Organizer
  The 23rd Korea-Japan Joint Seminar on Pharmacology Online
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07086
[Presentation] 遺伝性腎疾患Alport症候群の原因タンパク質を標的とした新規治療薬候補の同定及び薬効解析2021
- Author(s)
  桑水流淳、加世田将大、三宮裕也、新納咲紀、堀園潤、小山結実、Marry Ann Suico、首藤剛、甲斐広文
- Organizer
  日本薬学会第141回年会　オンライン学会
- Data Source
  KAKENHI-PROJECT-20K07086
[Presentation] 遺伝性腎疾患Alport症候群の原因タンパク質を標的とした新規治療薬候補の同定及び薬効解析2021
- Author(s)
  桑水流淳、加世田将大、三宮裕也、新納咲紀、堀園潤、小山結実、Marry Ann Suico、首藤剛、甲斐広文
- Organizer
  日本薬学会第141回年会　オンライン学会
- Data Source
  KAKENHI-PROJECT-19H03379
[Presentation] 遺伝性糸球体腎炎 Alport 症候群モデルマウスに対する可逆的 Keap1 阻害剤の腎保護効果2021
- Author(s)
  堀園潤、加世田将大、三宮裕也、桑水流淳、小木彩矢佳、佐々木亮子、砂本秀利、吹屋洋彦、西山勇人、嘉村美里、新納咲紀、小山結実、Mary Ann Suico、奈良太、首藤剛、大沼和弘、甲斐広文
- Organizer
  第12回トランスポーター研究会九州部会　オンライン学会
- Data Source
  KAKENHI-PROJECT-20K07086
[Presentation] 遺伝性糸球体腎炎 Alport 症候群モデルマウスに対する可逆的 Keap1 阻害剤の腎保護効果2021
- Author(s)
  堀園潤、加世田将大、三宮裕也、桑水流淳、小木彩矢佳、佐々木亮子、砂本秀利、吹屋洋彦、西山勇人、嘉村美里、新納咲紀、小山結実、Mary Ann Suico、奈良太、首藤剛、大沼和弘、甲斐広文
- Organizer
  第12回トランスポーター研究会九州部会オンライン学会
- Data Source
  KAKENHI-PROJECT-19H03379
[Presentation] 変異Ⅳ型コラーゲンの輸送・分泌を促進する遺伝性腎疾患Alport症候群の新規治療薬2020
- Author(s)
  桑水流淳、加世田将大、三宮裕也、新納咲紀、堀園潤、小山結実、Mary Ann Suico、首藤剛、甲斐広文
- Organizer
  第15回トランスポーター研究会年会　オンライン学会
- Data Source
  KAKENHI-PROJECT-20K07086
[Presentation] 遺伝性腎疾患Alport症候群に対する新規作用機序を有する薬物の同定及び薬効解析2020
- Author(s)
  桑水流淳、加世田将大、三宮裕也、新納咲紀、堀園潤、小山結実、Marry Ann Suico、首藤剛、甲斐広文
- Organizer
  第73回日本薬理学会西南部会　オンライン学会
- Data Source
  KAKENHI-PROJECT-20K07086
[Presentation] アンメットメディカルニーズの高い難治性疾患への挑戦 - ミッションに基づくアカデミア天然物創薬2020
- Author(s)
  首藤剛、Marry Ann Suico、Devkota Anjana、小澤享子、三隅将吾、岸本直樹、河原哲平、人羅勇気、塚本佐知子、甲斐広文、菊池正彦
- Organizer
  第73回日本薬理学会西南部会　オンライン学会
- Data Source
  KAKENHI-PROJECT-19H03379
[Presentation] 遺伝性腎疾患Alport症候群に対する新規作用機序を有する薬物の同定及び薬効解析2020
- Author(s)
  桑水流淳、加世田将大、三宮裕也、新納咲紀、堀園潤、小山結実、Marry Ann Suico、首藤剛、甲斐広文
- Organizer
  第73回日本薬理学会西南部会　オンライン学会
- Data Source
  KAKENHI-PROJECT-19H03379
[Presentation] 変異Ⅳ型コラーゲンの輸送・分泌を促進する遺伝性腎疾患Alport症候群の新規治療薬2020
- Author(s)
  桑水流淳、加世田将大、三宮裕也、新納咲紀、堀園潤、小山結実、Mary Ann Suico、首藤剛、甲斐広文
- Organizer
  第15回トランスポーター研究会年会　オンライン学会
- Data Source
  KAKENHI-PROJECT-19H03379
[Presentation] アンメットメディカルニーズの高い難治性疾患への挑戦 - ミッションに基づくアカデミア天然物創薬2020
- Author(s)
  首藤剛、Marry Ann Suico、Devkota Anjana、小澤享子、三隅将吾、岸本直樹、河原哲平、人羅勇気、塚本佐知子、甲斐広文、菊池正彦
- Organizer
  第73回日本薬理学会西南部会　オンライン学会
- Data Source
  KAKENHI-PROJECT-20K07086
[Presentation] Recent progress on high throughput screening-based search for therapeutic reagents against Alport syndrom2019
- Author(s)
  Hirofumi Kai, Mary Ann Suico, Tsuyoshi Shuto, Misato Kamura, Jun Kuwazuru, Haruka Kojima, Kohei Omachi
- Organizer
  The 2019 International workshop on Alport Syndrome Siena, Italy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03379
[Presentation] 遺伝性腎炎Alport症候群に対する代謝異常の改善を企図したmetforminの効果2019
- Author(s)
  加世田将大、大町紘平、横田翼、嘉村美里、寺本啓祐、小嶋遥、桑水流淳、大槻純男、Mary Ann Suico、首藤剛、甲斐広文
- Organizer
  第27回クリニカルファーマシーシンポジウム
- Data Source
  KAKENHI-PROJECT-17K08309
[Presentation] 各種アミロイドーシスに対するアミロイドブレーカーの探索研究2019
- Author(s)
  佐々木亮子、寺西ゆり子、帖佐圭佑、植田光晴、橋本那美、山縣章正、中野義雄、福島友太朗、小澤享子、Mary Ann Suico、首藤剛、安東由喜雄、甲斐広文
- Organizer
  第19回次世代創薬研究者養成塾ポスターフェス2019
- Data Source
  KAKENHI-PROJECT-19H03379
[Presentation] Adriamycin誘導性ネフローゼ症候群モデルに対する微弱パルス電流及び温熱同時印加の効果2019
- Author(s)
  寺本　啓祐、連川　雄、嘉村　美里、加世田　将大、小嶋　遥、桑水流　淳、大町　紘平、横田　翼、Mary Ann Suico、首藤　剛、甲斐　広文
- Organizer
  日本薬学会　第139年会
- Data Source
  KAKENHI-PROJECT-17K08309
[Presentation] 閉塞性肺疾患と亜鉛の意外な関係性～亜鉛トランスポーターの観点から2019
- Author(s)
  首藤　剛、亀井　竣輔、Mary Ann Suico、甲斐　広文
- Organizer
  第19回日本抗加齢医学会総会
- Data Source
  KAKENHI-PROJECT-19H03379
[Presentation] Drug discovery for Alport Syndrome by screening of natural products library2019
- Author(s)
  Mary Ann Suico, Jun Kuwazuru, Kohei Omachi, Misato Kamura, Tsuyoshi Shuto, Hirofumi Kai
- Organizer
  第19回次世代創薬研究者養成塾ポスターフェス2019
- Data Source
  KAKENHI-PROJECT-19H03379
[Presentation] 慢性閉塞性肺疾患モデルに対する甲状腺ホルモン（T3）経気管投与の影響2019
- Author(s)
  高橋宜暉、藤川春花、中嶋竜之介、江藤結花、那須葵、Marry Ann Suico、甲斐広文、首藤剛
- Organizer
  第11回トランスポーター研究会九州部会
- Data Source
  KAKENHI-PROJECT-19H03379
[Presentation] 各種アミロイドーシスに対するアミロイドブレーカーの探索研究2019
- Author(s)
  佐々木亮子、寺西ゆり子、帖佐圭佑、植田光晴、橋本那美、山縣章正、中野義雄、福島友太朗、小澤享子、Mary Ann Suico、首藤剛、安東由喜雄、甲斐広文
- Organizer
  第19回次世代創薬研究者養成塾ポスターフェス2019
- Data Source
  KAKENHI-PROJECT-17K08309
[Presentation] 慢性閉塞性肺疾患モデルに対する甲状腺ホルモン（T3）経気管投与の影響2019
- Author(s)
  高橋宜暉、藤川春花、中嶋竜之介、江藤結花、那須葵、Marry Ann Suico、甲斐広文、首藤剛
- Organizer
  第11回トランスポーター研究会九州部会
- Data Source
  KAKENHI-PROJECT-17K08309
[Presentation] メリンジョ種子抽出物（MSE）による慢性閉塞性肺疾患モデルマウスの肺病態抑制作用2019
- Author(s)
  那須葵、川上太聖、藤川春花、中嶋竜之介、江藤結花、野原寛文、鬼木健太郎、Mary Ann Suico、猿渡淳二、甲斐広文、首藤剛
- Organizer
  第11回トランスポーター研究会九州部会
- Data Source
  KAKENHI-PROJECT-17K08309
[Presentation] 遺伝性腎炎Alport症候群に対する代謝異常の改善を企図したmetforminの効果2019
- Author(s)
  加世田将大、大町紘平、横田翼、嘉村美里、寺本啓祐、小嶋遥、桑水流淳、大槻純男、Mary Ann Suico、首藤剛、甲斐広文
- Organizer
  第27回クリニカルファーマシーシンポジウム
- Data Source
  KAKENHI-PROJECT-19H03379
[Presentation] COPDモデルマウスに対する甲状腺ホルモン経気管投与の影響2019
- Author(s)
  高橋宜暉、藤川春花、中嶋竜之介、江藤結花、那須葵、Marry Ann Suico、甲斐広文、首藤剛
- Organizer
  第83回日本呼吸器学会・日本結核病学会　日本サルコイドーシス/肉芽腫性疾患学会　九州支部　秋季学術講演会
- Data Source
  KAKENHI-PROJECT-17K08309
[Presentation] COPDモデルマウスに対する甲状腺ホルモン経気管投与の影響2019
- Author(s)
  高橋宜暉、藤川春花、中嶋竜之介、江藤結花、那須葵、Marry Ann Suico、甲斐広文、首藤剛
- Organizer
  第83回日本呼吸器学会・日本結核病学会　日本サルコイドーシス/肉芽腫性疾患学会　九州支部　秋季学術講演会
- Data Source
  KAKENHI-PROJECT-19H03379
[Presentation] Alport 症候群におけるコラーゲン受容体 discoidin domain receptor 2の機能解明に向けた基礎的検討2019
- Author(s)
  三宮裕也、加世田将大、嘉村美里、桑水流淳、Mary Ann Suico、首藤剛、甲斐広文
- Organizer
  第72回日本薬理学会西南部会
- Data Source
  KAKENHI-PROJECT-17K08309
[Presentation] メリンジョ種子抽出物（MSE）による慢性閉塞性肺疾患モデルマウスの肺病態抑制作用2019
- Author(s)
  那須葵、川上太聖、藤川春花、中嶋竜之介、江藤結花、野原寛文、鬼木健太郎、Mary Ann Suico、猿渡淳二、甲斐広文、首藤剛
- Organizer
  第72回日本薬理学会西南部会
- Data Source
  KAKENHI-PROJECT-19H03379
[Presentation] Alport 症候群におけるコラーゲン受容体 discoidin domain receptor 2の機能解明に向けた基礎的検討2019
- Author(s)
  三宮裕也、加世田将大、嘉村美里、桑水流淳、Mary Ann Suico、首藤剛、甲斐広文
- Organizer
  第72回日本薬理学会西南部会
- Data Source
  KAKENHI-PROJECT-19H03379
[Presentation] 慢性閉塞性肺疾患モデルに対する甲状腺ホルモン（T3）経気管投与の影響2019
- Author(s)
  高橋宜暉、藤川春花、中嶋竜之介、江藤結花、那須葵、Marry Ann Suico、甲斐広文、首藤剛
- Organizer
  第36回日本薬学会九州支部大会
- Data Source
  KAKENHI-PROJECT-19H03379
[Presentation] 閉塞性肺疾患と亜鉛の意外な関係性～亜鉛トランスポーターの観点から2019
- Author(s)
  首藤　剛、亀井　竣輔、Mary Ann Suico、甲斐　広文
- Organizer
  第19回日本抗加齢医学会総会
- Data Source
  KAKENHI-PROJECT-17K08309
[Presentation] メリンジョ種子抽出物（MSE）による慢性閉塞性肺疾患モデルマウスの肺病態抑制作用2019
- Author(s)
  那須葵、川上太聖、藤川春花、中嶋竜之介、江藤結花、野原寛文、鬼木健太郎、Mary Ann Suico、猿渡淳二、甲斐広文、首藤剛
- Organizer
  第11回トランスポーター研究会九州部会
- Data Source
  KAKENHI-PROJECT-19H03379
[Presentation] 慢性閉塞性肺疾患モデルに対する甲状腺ホルモン（T3）経気管投与の影響2019
- Author(s)
  高橋宜暉、藤川春花、中嶋竜之介、江藤結花、那須葵、Marry Ann Suico、甲斐広文、首藤剛
- Organizer
  第36回日本薬学会九州支部大会
- Data Source
  KAKENHI-PROJECT-17K08309
[Presentation] Drug discovery for Alport Syndrome by screening of natural products library2019
- Author(s)
  Mary Ann Suico, Jun Kuwazuru, Kohei Omachi, Misato Kamura, Tsuyoshi Shuto, Hirofumi Kai
- Organizer
  第19回次世代創薬研究者養成塾ポスターフェス2019
- Data Source
  KAKENHI-PROJECT-17K08309
[Presentation] メリンジョ種子抽出物（MSE）による慢性閉塞性肺疾患モデルマウスの肺病態抑制作用2019
- Author(s)
  那須葵、川上太聖、藤川春花、中嶋竜之介、江藤結花、野原寛文、鬼木健太郎、Mary Ann Suico、猿渡淳二、甲斐広文、首藤剛
- Organizer
  第72回日本薬理学会西南部会
- Data Source
  KAKENHI-PROJECT-17K08309
[Presentation] Therapeutic potential of metformin in novel COPD mouse model with diffuse-type emphysema2019
- Author(s)
  Ryunosuke Nakashima, Hirofumi Nohara, Shunsuke Kamei, Haruka Fujikawa, Kasumi Maruta, Taisei Kawakami, Yuka Eto, Noriki Takahashi, Aoi Nasu, Mary-Ann Suico, Hirofumi Kai, Tsuyoshi Shuto
- Organizer
  ASCB|EMBO 2019 meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03379
[Presentation] Recent progress on high throughput screening-based search for therapeutic reagents against Alport syndrome2019
- Author(s)
  Hirofumi Kai, Mary Ann Suico, Tsuyoshi Shuto, Misato Kamura, Jun Kuwazuru, Haruka Kojima, Kohei Omachi
- Organizer
  The 2019 International workshop on Alport Syndrome
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08309
[Presentation] Therapeutic potential of metformin in novel COPD mouse model with diffuse-type emphysema2019
- Author(s)
  Ryunosuke Nakashima, Hirofumi Nohara, Shunsuke Kamei, Haruka Fujikawa, Kasumi Maruta, Taisei Kawakami, Yuka Eto, Noriki Takahashi, Aoi Nasu, Mary-Ann Suico, Hirofumi Kai, Tsuyoshi Shuto
- Organizer
  ASCB|EMBO 2019 meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08309
[Presentation] アンメット・メディカル・ニーズの高い難治性疾患に対する創薬研究2018
- Author(s)
  首藤　剛、Mary Ann Suico、甲斐　広文
- Organizer
  第22回天然薬物の開発と応用シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-17K08309
[Presentation] Alport症候群に対する新規治療法としてのMetforminの有用性2018
- Author(s)
  加世田将大、大町紘平、横田翼、嘉村美里、寺本啓祐、桑水流淳、大槻純男、Mary Ann Suico、首藤剛、甲斐広文
- Organizer
  第35回日本薬学会　九州支部大会
- Data Source
  KAKENHI-PROJECT-17K08309
[Presentation] 抗ネフリン抗体を用いた新規糸球体硬化モデルの確立に向けた基礎的検討2018
- Author(s)
  桑水流淳、大町紘平、嘉村美里、寺本啓祐、加世田将大、Mary Ann Suico、首藤剛、川島　永子、内藤　正吉、甲斐広文
- Organizer
  第35回日本薬学会　九州支部大会
- Data Source
  KAKENHI-PROJECT-17K08309
[Presentation] Adriamycin誘導性ネフローゼ症候群モデルに対する微弱パルス電流及び温熱同時印可の効果2018
- Author(s)
  寺本啓祐、連川　雄、嘉村美里、加世田将大、小嶋遥、桑水流淳、大町紘平、横田翼、Mary Ann Suico、首藤剛、甲斐広文
- Organizer
  第71回日本薬理学会　西南部会
- Data Source
  KAKENHI-PROJECT-17K08309
[Presentation] A split-luciferase-based trimer formation assay as a high-throughput screening platform for therapeutics in Alport syndrome2018
- Author(s)
  Mary Ann Suico, Kohei Omachi, Misato Kamura, Keisuke Teramoto, Haruka Kojima, Tsubasa Yokota, Shota Kaseda, Jun Kuwazuru, Tsuyoshi Shuto, Hirofumi Kai
- Organizer
  WCP2018 KYOTO
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08309
[Presentation] STAT3阻害はアルポート症候群の腎病態進展を抑制する2017
- Author(s)
  横田　翼、大町　紘平、福田　亮介、Suico　Mary Ann、首藤　剛、甲斐　広文
- Organizer
  第６０回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-17K08309
[Presentation] がん抑制遺伝子 p53 の podocyte における役割と podocyte 障害性腎症への関与2017
- Author(s)
  嘉村美里、大町紘平、横田翼、寺本啓祐、小嶋遥、桑水流淳、福田亮介、Suico Mary Ann、首藤剛、甲斐広文
- Organizer
  第５２回小児腎臓病学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08309
[Presentation] アンジオテンシンII受容体拮抗薬による遺伝性腎疾患アルポート症候群の治療効果メカニズムの解明2017
- Author(s)
  加世田　将大、大町　紘平、Suico Mary Ann、首藤　剛、甲斐　広文
- Organizer
  第６０回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-17K08309
[Presentation] タンパク質フォールディングは遺伝性腎炎アルポート症候群の新たな標的となり得るか2017
- Author(s)
  甲斐広文, 大町紘平, Mary Ann Suico, 首藤剛
- Organizer
  第９０回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール（長崎）
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-26460098
[Presentation] CLARIFY THE INTRACELLULAR STRESS RESPONSE IN EARLY-STAGE ALPORT SYNDROME AND ESTABLISH AN EVALUATION SYSTEM FOR INTRACELLULAR REGULATION OF COL4A52017
- Author(s)
  K. OMACHI, K. TERAMOTO, M. KAMURA, H. KOJIMA, T. YOKOTA, M.A. SUICO, T. SHUTO, H. KAI
- Organizer
  17th Congress of the International Pediatoric Nephrology Association (IPNA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08309
[Presentation] アルポート症候群原因タンパク質 α345(IV) 三量体形成の HTS 評価系の確立と治療応用2017
- Author(s)
  大町　紘平、寺本　啓祐、嘉村　美里、Suico Mary Ann、首藤　剛、甲斐　広文
- Organizer
  第６０回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-17K08309
[Presentation] Adriamycin 誘導性腎障害モデルに対する微弱パルス電流・温熱同時印加の影響2017
- Author(s)
  寺本啓祐、大町紘平、横田翼、嘉村美里、連川雄、加世田翔太、小嶋遥、桑水流淳、Mary Ann Suico、首藤剛、甲斐広文
- Organizer
  第12回トランスポーター研究会年会
- Data Source
  KAKENHI-PROJECT-17K08309
[Presentation] アンジオテンシンII受容体拮抗薬による遺伝性腎疾患アルポート症候群の治療効果メカニズムの解明2017
- Author(s)
  加世田翔大，大町紘平，横田翼，小嶋遥，嘉村美里，寺本啓祐，Mary Ann Suico，首藤剛，甲斐広文
- Organizer
  第９０回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール（長崎）
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-26460098
[Presentation] Adriam誘導性腎障害モデルに対する微弱パルス電流・温熱同時印加の影響2017
- Author(s)
  寺本啓祐、大町紘平、横田翼、嘉村美里、連川雄、加世田将大、小嶋遥、桑水流淳、Mary Ann Suico、首藤剛、甲斐広文
- Organizer
  第10回トランスポーター研究会九州部会
- Data Source
  KAKENHI-PROJECT-17K08309
[Presentation] High throughput screening system of type IV collagen α 345 trimer2017
- Author(s)
  Kohei Omachi, Misato Kamura, Keisuke Teramoto, Haruka Kojima, Tsubasa Yokota, Shota Kaseda, Jun Kuwazuru, Mary Ann Suco, Tsuyoshi Shuto, Hirofumi Kai
- Organizer
  第５２回小児腎臓病学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08309
[Presentation] p53のpodocyteにおける役割とpodocyte障害性腎症への関与2017
- Author(s)
  嘉村　美里、大町　紘平、横田　翼、寺本　啓祐、加世田　将大、小嶋　遥、福田　亮介、Suico Mary Ann、首藤　剛、甲斐　広文
- Organizer
  第６０回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-17K08309
[Presentation] 遺伝性腎炎アルポート症候群に対するSTAT3抑制薬は後期腎病態の進展を抑制する2017
- Author(s)
  横田翼，大町紘平，嘉村美里，小嶋遥，寺本啓祐，加世田翔大，桑水流淳，福田亮介，Mary Ann Suico，首藤剛，甲斐広文
- Organizer
  第９０回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール（長崎）
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-26460098
[Presentation] Effects of inhibition of GRFR and STAT3 signals on renal phenotypes of Alport syndrome mouse model2017
- Author(s)
  Mary Ann Suico, Tsubasa Yokota, Kohei Omachi, Misato Kamura, Haruka Kojima, Jun Kuwazuru, Tsuyoshi Shuto, Hirofumi Kai
- Organizer
  第34回日本薬学会九州支部大会
- Data Source
  KAKENHI-PROJECT-17K08309
[Presentation] Metforminによる進行性子宮体腎炎に対する保護効果2017
- Author(s)
  加世田将大、大町紘平、桑水流淳、横田翼、嘉村美里、寺本啓祐、小嶋遥、Mary Ann Suico、首藤剛、大槻純男、甲斐広文
- Organizer
  第39回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-17K08309
[Presentation] 代謝異常の改善を企図した遺伝性腎疾患アルポート症候群に対する新規治療法の確立2017
- Author(s)
  加世田将大、大町紘平、横田翼、嘉村美里、寺本啓祐、小嶋遥、桑水流淳、Mary Ann Suico、首藤剛、甲斐広文
- Organizer
  第10回トランスポーター研究会九州部会
- Data Source
  KAKENHI-PROJECT-17K08309
[Presentation] 原因タンパク質を標的とした遺伝性腎炎アルポート症候群の創薬基盤の構築2017
- Author(s)
  大町紘平，嘉村美里，寺本啓祐，小嶋遥，横田翼，加世田翔大，Mary Ann Suico，首藤剛，甲斐広文
- Organizer
  第９０回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール（長崎）
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-26460098
[Presentation] SIRT1 IS UP-REGULATED BY ER STRESS VIA THE PI3K-AKT-GSK3βPATHWAY AND MEDIATES ER STRESS-INDUCED HEPATOCELLULAR INJURY2016
- Author(s)
  Tomoaki Koga, Mary Ann Suico, Shogo Shimasaki, Eriko Watanabe, Yukari Kai, Kosuke Koyama, Kohei Omachi, Saori Morino-Koga, Takashi Sato, Tsuyoshi Shuto, Kazutoshi Mori, Shinjiro Hino, Mitsuyoshi Nakao, Hirofumi Kai
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（神奈川）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-26460098
[Presentation] CLARIFY THE INTRACELLULAR STRESS RESPONSE IN EARLY-STAGE ALPORT SYNDROME AND ESTABLISH AN EVALUATION SYSTEM FOR INTRACELLULAR REGULATION OF COL4A52016
- Author(s)
  K. OMACHI, K. TERAMOTO, M. KAMURA, H. KOJIMA, T. YOKOTA, M.A. SUICO, T. SHUTO, H. KAI
- Organizer
  17th Congress of the International Pediatoric Nephrology Association (IPNA)
- Place of Presentation
  Iguacu, Brazil
- Year and Date
  2016-09-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460098
[Presentation] 遺伝性腎炎アルポート症候群に対するSTAT3抑制薬は後期腎病態の進展を抑制する2016
- Author(s)
  横田翼，大町紘平，嘉村美里，小嶋遥，寺本啓祐，加世田翔大，桑水流淳，福田亮介，Mary Ann Suico，首藤剛，甲斐広文
- Organizer
  第１０回次世代を担う若手医療薬科学シンポジウム
- Place of Presentation
  群馬大学昭和キャンパス（群馬）
- Year and Date
  2016-11-05
- Data Source
  KAKENHI-PROJECT-26460098
[Presentation] HIF-1α activates the ETS factor myeloid elf-1-like factor (MEF)/ELF42016
- Author(s)
  Mary Ann Suico, Manabu Taura, Eriko Kudo, Kumiko Gotoh, Tsuyoshi Shuto, Seiji Okada, Hirofumi Kai
- Organizer
  第６９回日本薬理学会西南部会
- Place of Presentation
  松山大学（愛媛）
- Data Source
  KAKENHI-PROJECT-26460098
[Presentation] 6-benzoyl-2-hydroxy-1H-benzo[de]isoquin oline-1,3(2H)-dione is a novel transthyretin stabilizer for familial amyloid polyneuropathy2015
- Author(s)
  S. Takaki, K. Chosa, T. Yokoyama, Y. Teranishi, Y. Wakita, T. Sato, M. Suico, T. Shuto, M. Mizuguchi, H. Kai
- Organizer
  International Symposium on Chronic Inflammatory Diseases, Kumamoto (ISCIDK2015)
- Place of Presentation
  熊本大学（熊本）
- Year and Date
  2015-10-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25253012
[Presentation] Myeloid Elf-1-like Factor (MEF)/Elf-4 is Induced by HIF1/Hypoxia and contributes to VEGF regulation2015
- Author(s)
  Mary Ann Suico, Manabu Taura, Eriko Kudo, Tsuyoshi Shuto, Seiji Okada, Hirofumi Kai
- Organizer
  The 74th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Nagoya Congress Center（愛知）
- Year and Date
  2015-10-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460098
[Presentation] Characterization of the intracellular behavior of COL4A5 and clarification of molecular mechanism of alport syndrome2015
- Author(s)
  K. Omachi, M. Kamura, K. Teramoto, R. Fukuda, M. Suico, T. Shuto, H. Kai
- Organizer
  52nd ERA-EDTA CONGRESS LONDON 2015
- Place of Presentation
  London（UK）
- Year and Date
  2015-05-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25253012
[Presentation] Podocyte p53 limits the severity of experimental Alport syndrome2015
- Author(s)
  M.A. Suico, R. Fukuda, Y. Kai, K. Omachi, K. Motomura, T. Koga, K. Koyama, T. Yokota, M. Taura, T. Shuto, H. Kai
- Organizer
  International Symposium on Chronic Inflammatory Diseases, Kumamoto (ISCIDK2015)
- Place of Presentation
  熊本大学薬学部（熊本）
- Year and Date
  2015-10-16
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460098
[Presentation] Glomerular proteome analysis reveals progressive mitochondrial dysfunction in Alport syndrome mouse model2015
- Author(s)
  M. Kamura, K. Omachi, K. Teramoto, T. Yokota, K. Motomura, S. Kotani, M. Suico, T. Shuto, S. Misumi, H. Kai
- Organizer
  International Symposium on Chronic Inflammatory Diseases, Kumamoto (ISCIDK2015)
- Place of Presentation
  熊本大学薬学部（熊本）
- Year and Date
  2015-10-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460098
[Presentation] Hsp47によるTTRタンパク質の細胞内品質管理機構の解明2015
- Author(s)
  脇田有梨子、山川瑠斐子、帖佐圭佑、高木舜、寺西ゆり子、佐藤卓史、Mary Ann Suico、首藤剛、甲斐広文
- Organizer
  第32回日本薬学会九州支部大会
- Place of Presentation
  九州保健福祉大学（宮崎）
- Year and Date
  2015-11-28
- Data Source
  KAKENHI-PROJECT-25253012
[Presentation] Characterization of the intracellular behavior of COL4A5 and clarification of molecular mechanism of alport syndrome2015
- Author(s)
  K. Omachi, M. Kamura, K. Teramoto, R. Fukuda, M. Suico, T. Shuto, H. Kai
- Organizer
  52nd ERA-EDTA CONGRESS LONDON 2015
- Place of Presentation
  London（UK）
- Year and Date
  2015-05-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460098
[Presentation] Molecular mechanism of the intracellular quality control of TTR by Hsp472015
- Author(s)
  Y. Wakita, R. Yamakawa, K. Chosa, S. Takaki, Y. Teranishi, T. Sato, M.Suico, T. Shuto, H. Kai
- Organizer
  2015 cell biology ascb annual meeting
- Place of Presentation
  San Diego(USA)
- Year and Date
  2015-12-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25253012
[Presentation] 腎糸球体基底膜構成因子COL4A5の細胞内品質管理機構と病態初期変動因子に着目した遺伝性腎炎治療標的分子の探索2015
- Author(s)
  大町紘平、嘉村美里、寺本啓祐、横田翼、本村敬士、山川瑠斐子、Mary Ann Suico、首藤剛、甲斐広文
- Organizer
  第37回生体膜と薬物の相互作用シンポジウム2015
- Place of Presentation
  熊本大学薬学部（熊本）
- Year and Date
  2015-11-19
- Data Source
  KAKENHI-PROJECT-26460098
[Presentation] 遺伝性腎炎Alport症候群の原因タンパク質COL4A5の分解機能とER chaperone による細胞内品質管理機構の解明2015
- Author(s)
  大町紘平、嘉村美里、寺本啓祐、横田翼、福田亮介、本村敬士、山川瑠斐子、Mary Ann Suico、首藤剛、甲斐広文
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド（兵庫）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26460098
[Presentation] p53 exacerbates LPS-induced acute kidney injury possibly through TLR4 up-regulation in podocyte2015
- Author(s)
  K. Motomura, R. Fukuda, T Yokota, M. Suico, T. Shuto, H. Kai
- Organizer
  International Symposium on Chronic Inflammatory Diseases, Kumamoto (ISCIDK2015)
- Place of Presentation
  熊本大学薬学部（熊本）
- Year and Date
  2015-10-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460098
[Presentation] Hsp47によるTTRタンパク質の細胞内品質管理機構の解明2015
- Author(s)
  脇田有梨子、山川瑠斐子、帖佐圭佑、高木舜、寺西ゆり子、佐藤卓史、Mary Ann Suico、首藤剛、甲斐広文
- Organizer
  第37回生体膜と薬物の相互作用シンポジウム2015
- Place of Presentation
  熊本大学薬学部（熊本）
- Year and Date
  2015-11-19
- Data Source
  KAKENHI-PROJECT-25253012
[Presentation] Hsp47によるTTRタンパク質の細胞内品質管理機構の解明2015
- Author(s)
  脇田有梨子、山川瑠斐子、帖佐圭佑、高木舜、寺西ゆり子、佐藤卓史、Mary Ann Suico、首藤剛、甲斐広文
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド（兵庫）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25253012
[Presentation] Clarify the intracellular stress response in early-stage Alport Syndrome (AS) and establish an evaluation system for intracellular regulation of COL4A5, the causal protein for AS2015
- Author(s)
  K. Omachi, M. Kamura, K. Teramoto, T. Yokota, K. Motomura, R. Fukuda, M. Suico, T. Shuto, H. Kai
- Organizer
  International Symposium on Chronic Inflammatory Diseases, Kumamoto (ISCIDK2015)
- Place of Presentation
  熊本大学薬学部（熊本）
- Year and Date
  2015-10-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460098
[Presentation] High throughput screening-based identification of transthyretin stabilizers for familial amyloid polyneuropathy2015
- Author(s)
  Y. Teranishi, K. Chosa, T. Shuto, S. Takaki, Y. Wakita, T. Sato, M. Suico, T. Yamashita, H. Kai
- Organizer
  International Symposium on Chronic Inflammatory Diseases, Kumamoto (ISCIDK2015)
- Place of Presentation
  熊本大学（熊本）
- Year and Date
  2015-10-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25253012
[Presentation] 遺伝性腎炎Alport症候群の病態進行抑制因子および原因タンパク質に焦点を当てた新規治療薬の開発2015
- Author(s)
  大町紘平, 福田亮介, 嘉村美里, 寺本啓祐, 横田翼, 本村敬士, 山川瑠斐子, Mary Ann Suico, 首藤剛, 甲斐広文
- Organizer
  第6回分子腎臓フォーラム
- Place of Presentation
  グランフロント大阪（大阪）
- Year and Date
  2015-09-05
- Data Source
  KAKENHI-PROJECT-26460098
[Presentation] バーチャルスクリーニングシステムを活用した、家族性アミロイドポリニューロパチー原因タンパク質 TTR の四量体安定化剤の同定2015
- Author(s)
  高木舜、帖佐圭佑、横山武司、佐藤卓史、Mary Ann Suico、寺西ゆり子、首藤剛、水口峰之、甲斐広文
- Organizer
  第37回生体膜と薬物の相互作用シンポジウム2015
- Place of Presentation
  熊本大学薬学部（熊本）
- Year and Date
  2015-11-19
- Data Source
  KAKENHI-PROJECT-25253012
[Presentation] 遺伝性腎炎Alport症候群の病態進行抑制因子および原因タンパク質に焦点を当てた新規治療薬の開発2015
- Author(s)
  大町紘平, 福田亮介, 嘉村美里, 寺本啓祐, 横田翼, 本村敬士, 山川瑠斐子, Mary Ann Suico, 首藤剛, 甲斐広文
- Organizer
  第6回分子腎臓フォーラム
- Place of Presentation
  グランフロント大阪（大阪）
- Year and Date
  2015-09-05
- Data Source
  KAKENHI-PROJECT-25253012
[Presentation] Glomerular proteome analysis revealed progressive mitochondrial dysfunction in Alport syndrome mouse model2015
- Author(s)
  M. Kamura, K. Omachi, T. Yokota, K. Motomura, K. Teramoto, M. Suico, T. Shuto, H. Kai
- Organizer
  2015 cell biology ascb annual meeting
- Place of Presentation
  San Diego(USA)
- Year and Date
  2015-12-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460098
[Presentation] Elucidation of quality control mechanism of COL4A5 and new insight into the pathogenesis of Alport syndrome2015
- Author(s)
  K. Omachi, M. Kamura, K. Teramoto, T. Yokota, K. Motomura, R. Fukuda, MA Suico, T. Shuto, H. Kai
- Organizer
  第9回次世代を担う若手医療薬科学シンポジウム
- Place of Presentation
  千葉大学薬学部（千葉）
- Year and Date
  2015-11-07
- Data Source
  KAKENHI-PROJECT-26460098
[Presentation] Podocyte p53 limits the severity of experimental Alport syndrome2015
- Author(s)
  Mary Ann Suico, Ryosuke Fukuda, Yukari Kai, Kohei Omachi, Keishi Motomura, Tomoaki Koga, Kosuke Koyama, Tsubasa Yokota, Manabu Taura, Tsuyoshi Shuto, Hirofumi Kai
- Organizer
  第68回日本薬理学会西南部会
- Place of Presentation
  海峡メッセ下関（山口）
- Year and Date
  2015-11-21
- Data Source
  KAKENHI-PROJECT-26460098
[Presentation] Functional interplay of p53 and TLR links immune response and cancer2014
- Author(s)
  Mary Ann SUICO
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23590082
[Presentation] The endoplasmic reticulum-oriented drug development for transthyretin familial amyloid polyneuropathy2013
- Author(s)
  Keisuke Chosa , Ruiko Yamakawa , Takashi Sato , Takeshi Yokoyama , Mineyuki Mizuguchi , Mary Ann Suico ,Tsuyoshi Shuto , Hirofumi Kai
- Organizer
  IXth International Symposium on Familial Amyloidotic Polyneuropathy
- Place of Presentation
  Auditorio do Centro de Convencoes Antonio Seabra Moggi,Rio de Janeiro, Brazil
- Data Source
  KAKENHI-PROJECT-25253012
[Presentation] 翻訳後 N型糖鎖修飾を介した小胞体品質管理機構による家族性アミロイドーシスの発症性制御機構の解明2013
- Author(s)
  佐藤卓史, 庄美里, スイコメリーアン, 首藤剛, 甲斐広文
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パシフィコ横浜(横浜)
- Data Source
  KAKENHI-PROJECT-22390015
[Presentation] Crucial role of basal p53 in attenuation of inflammation and fibrosis in hereditary glomerular nephritis, Alport syndrome2013
- Author(s)
  R. Fukuda, K. Koyama, T. Koga, Y. Kai, K. Omachi, K. Motomura, M. A. Suico, T. Shuto, H. Kai
- Organizer
  15th International congress of immunology
- Place of Presentation
  Mico Milano Congressi, Milano, ITALY
- Data Source
  KAKENHI-PROJECT-23590082
[Presentation] The endoplasmic reticulum-oriented drug development for familial amyloid polyneuropathy2013
- Author(s)
  K. Chosa, R. Yamakawa, T. Sato, T. Yokoyama, M. Mizuguchi, M. Suico, T. Shuto, H. Kai
- Organizer
  2013 ASCB Annual Meeting
- Place of Presentation
  The New Orleans Ernest N. Morial Convention Center, New Orleans, Lousiana,USA
- Data Source
  KAKENHI-PROJECT-25253012
[Presentation] 慢性腎疾患 Alport syndrome モデルマウスを用いた癌抑制遺伝子 p53 の腎保護的機能の解明2013
- Author(s)
  福田亮介, 小山皓介, 古賀友紹,甲斐友佳理, スイコメリーアン, 大町紘平, 本村敬士, 首藤剛, 甲斐広文
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡国際会議場(福岡)
- Data Source
  KAKENHI-PROJECT-22390015
[Presentation] 異常な構造を持つ分泌タンパク質の新たな小胞体品質管理機構2013
- Author(s)
  庄美里, 佐藤卓史, 帖佐圭佑,山川瑠斐子, スイコメリーアン, 首藤剛, 甲斐広文
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡国際会議場(福岡)
- Data Source
  KAKENHI-PROJECT-22390015
[Presentation] p53 regulates the Ets trascription factor MEF/Elf4 via MDM22013
- Author(s)
  スイコ　メリーアン
- Organizer
  第２回次世代創薬研究者養成塾
- Place of Presentation
  熊本大学薬学部（熊本市中央区）
- Data Source
  KAKENHI-PROJECT-23590082
[Presentation] Specific pulse-width mild electrical stimulation induces p53 activation via p38 MAPK and ameliorates LPS-induced inflammatory cytokine response2013
- Author(s)
  R. Fukuda, K. Omachi, M. A. Suico, K. Koyama, Y. Kai, S. Matsuyama, K. Mitsutake, S. Morino-Koga, T. Shuto, H. Kai
- Organizer
  15th International congress of immunology
- Place of Presentation
  Mico Milano Congressi, Milano, ITALY
- Data Source
  KAKENHI-PROJECT-23590082
[Presentation] STT3B-dependentposttranslational N-glycosylation as asurveillance system for secretoryprotein2012
- Author(s)
  Kai H, Sato T, Sho M, Sako Y, M. A. Suico, Shuto T
- Organizer
  Quality Control FromMolecules to Organelles
- Place of Presentation
  EMB Advenced TrainingCentre,Heidelberg(Germany)
- Data Source
  KAKENHI-PROJECT-22390015
[Presentation] p53 regulates theEts transcription factor MEF/Elf4 viaMDM22012
- Author(s)
  M. Suico, R. Miyakita, K. Koyama, M.Taura,T. Shuto, H. Kai
- Organizer
  ASCB 2012 Annual Meeting
- Place of Presentation
  Moscone Center, SanFrancisco(USA)
- Data Source
  KAKENHI-PROJECT-22390015
[Presentation] p53 regulates the Ets transcription factor MEF/Elf4 via MDM22012
- Author(s)
  Mary Ann SUICO
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  北海道
- Data Source
  KAKENHI-PROJECT-23590082
[Presentation] 慢性腎疾患 Alport syndrome モデルマウスを用いた癌抑制遺伝子 p53 の腎保護的機能の解明2012
- Author(s)
  福田亮介, 小山皓介, 古賀友紹,甲斐友佳理, Mary Ann Suico, 首藤剛,甲斐広文
- Organizer
  第65回日本薬理学会西南部会
- Place of Presentation
  熊本大学(熊本)
- Year and Date
  2012-11-23
- Data Source
  KAKENHI-PROJECT-22390015
[Presentation] p53 regulates the Ets transcription factor MEF/Elf4 via MDM22012
- Author(s)
  Mary Ann SUICO
- Organizer
  ASCB 2012 Annual Meeting
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-23590082
[Presentation] p53 regulates the Ets transcription factor MEF/Elf4 via MDM22012
- Author(s)
  M. Suico
- Organizer
  ASCB 2012 Annual Meeting
- Place of Presentation
  San Francisco, CA, USA
- Data Source
  KAKENHI-PROJECT-23590082
[Presentation] p53 regulates the Ets transcription factor MEF/Elf4 via MDM2012
- Author(s)
  Mary Ann Suico
- Organizer
  第71回日本癌学会学術総会-がん研究とライフサイエンスの更なるリエゾン-
- Place of Presentation
  ロイトン札幌（北海道）
- Data Source
  KAKENHI-PROJECT-23590082
[Presentation] p53 regulates the Ets transcription factor MEF/Elf4 via MDM2.2012
- Author(s)
  M. Suico
- Organizer
  ASCB 2012 Annual Meeting
- Place of Presentation
  San Francisco, CA, USA
- Data Source
  KAKENHI-PROJECT-22390015
[Presentation] 遺伝性腎疾患alport症候群に対する新たなphysical medicineの腎病態改善効果2011
- Author(s)
  甲斐　友佳理、古賀　友紹、福田　亮介、古賀（森野）　沙緒里、メリーアン　スイコ、小山　皓介、佐藤　卓史、首藤　剛、甲斐　広文
- Organizer
  第28回日本薬学会九州支部大会
- Place of Presentation
  福岡大学薬学部（福岡）
- Data Source
  KAKENHI-PROJECT-23590082
[Presentation] Protective effects of p53 in a mouse model of progressive hereditary kidney disease Alport syndrome.2011
- Author(s)
  R. Fukuda, K. Koyama, T. Koga, Y. Kai, M. A. Suico, T. Shuto, H. Kai
- Organizer
  ASCB 51st Annual Meeting
- Place of Presentation
  Colorado Convention Center,Denver(USA)
- Data Source
  KAKENHI-PROJECT-23590082
[Presentation] Mild electrical stimulation suppresses fat accumulation and increases stress resistance via mitochondrial membrane potentioal-dependent activation of AMP-activated protein kinase.2011
- Author(s)
  Shingo Matsuyama, Shuichiro Yano, Saori Koga-Morino, Yuichiro Shimauchi, Yuka Okamoto, Ihori Shitanda, Mary Ann Suico, Tsuyoshi Shuto, Hirofumi Kai
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川）
- Data Source
  KAKENHI-PROJECT-23590082
[Presentation] 翻訳後 N 型糖鎖修飾によるトランスサイレチンの新規小胞体品質管理機構2011
- Author(s)
  庄美里、佐藤卓史、迫康弘、桃原真美子、西頭英起、金子雅幸、メリーアンスイコ、首藤剛、甲斐広文
- Organizer
  第28回日本薬学会九州支部大会
- Place of Presentation
  福岡大学薬学部(福岡)
- Year and Date
  2011-11-14
- Data Source
  KAKENHI-PROJECT-22390015
[Presentation] Mef/Elf4 transactivation by E2F1 is inhibited by p532011
- Author(s)
  Mary Ann SUICO
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23590082
[Presentation] ABCトランスポーター ABCG5 および ABCG8 の小胞体における翻訳後発現制御機構の解明2011
- Author(s)
  鈴木伸悟,首藤剛,佐藤卓史,金子雅幸,Mary Ann Suico,甲斐広文
- Organizer
  第5回トランスポーター研究会九州部会
- Place of Presentation
  ホテル JAL シティ宮崎(宮崎)
- Year and Date
  2011-09-17
- Data Source
  KAKENHI-PROJECT-22390015
[Presentation] 糖鎖型および脱糖鎖型 BCRP タンパク質の Derlin-1による負の翻訳後発現調節2011
- Author(s)
  首藤剛,杉山崇,鈴木伸悟,佐藤卓史,古賀友紹,Mary Ann Suico,楠原洋之,杉山雄一,甲斐広文
- Organizer
  第5回トランスポーター研究会九州部会
- Place of Presentation
  ホテル JAL シティ宮崎(宮崎)
- Year and Date
  2011-09-17
- Data Source
  KAKENHI-PROJECT-22390015
[Presentation] HRD1-dependent endoplasmic reticulum-associated degradation pathway is involved in the clearance of transthyretin variant.2011
- Author(s)
  Misato Sho, Takashi Sato, Yasuhiro Sako, Mamiko Momohara, Hideki Nishitoh, Masayuki Kaneko, Mary Ann Suico, Tsuyoshi Shuto and Hirofumi Kai
- Organizer
  5th International Congress on Stress Response in Biology and Medicine
- Place of Presentation
  Loews Hotel Le Concorde,Quebec(Canada)
- Data Source
  KAKENHI-PROJECT-23590082
[Presentation] ストレス耐性付与および脂肪蓄積抑制作用を有する新たなphysical medicine2011
- Author(s)
  松山　真吾、矢野　脩一郎、古賀（森野）　佐緒里、島内　裕一郎、岡本　友加、四反田　伊穂李、メリーアン　スイコ、首藤　剛、甲斐　広文
- Organizer
  第28回日本薬学会九州支部大会
- Place of Presentation
  福岡大学薬学部（福岡）
- Data Source
  KAKENHI-PROJECT-23590082
[Presentation] 糖鎖型および脱糖鎖型 BCRP タンパク質の Derlin-1による負の翻訳後発現調節2011
- Author(s)
  首藤剛,杉山崇,鈴木伸悟,佐藤卓史,古賀友紹,Mary Ann Suico,楠原洋之,杉山雄一,甲斐広文
- Organizer
  第6回トランスポーター研究会年会
- Place of Presentation
  東北大学片平さくらホール(宮城県)
- Data Source
  KAKENHI-PROJECT-22390015
[Presentation] HRD1-dependentendoplasmic reticulum-associateddegradation pathway is involved in theclearance of transthyretin variant2011
- Author(s)
  M. Sho, T. Sato, Y. Sako, M. Momohara,H. Nishitoh, M. Kaneko, M. A. Suico, T.Shuto, H. Kai
- Organizer
  5thInternational Congress on Stress Responsein Biology and Medicine
- Place of Presentation
  Loews Hotel Le Concorde,Quebec(USA)
- Data Source
  KAKENHI-PROJECT-22390015
[Presentation] 糖尿病性腎症に対する新たなphysical medicineの病態改善効果2011
- Author(s)
  岡本　有加、古賀（森野）　沙緒里、古賀　友紹、大町　紘平、メリーアン　スイコ、首藤　剛、甲斐　広文
- Organizer
  第28回日本薬学会九州支部大会
- Place of Presentation
  福岡大学薬学部（福岡）
- Data Source
  KAKENHI-PROJECT-23590082
[Presentation] The tumor suppressor Retinoblastoma protein positively regulates innate immune receptor Toll-like receptor 3 in epithelial cells.2011
- Author(s)
  Kosue Koyama, Manabu Taura, Mary Ann Suico, Tsuyoshi Shuto, Seiji Okada, Hirofumi Kai
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川）
- Data Source
  KAKENHI-PROJECT-23590082
[Presentation] 翻訳後N型糖鎖修飾によるトランスサイレチンの新規小胞体品質管理機構2011
- Author(s)
  庄　美里、佐藤　卓史、迫　康弘、桃原　真美子、西頭　英起、金子　雅幸、メリーアン　スイコ、首藤　剛、甲斐　広文
- Organizer
  第28回日本薬学会九州支部大会
- Place of Presentation
  福岡大学薬学部（福岡）
- Data Source
  KAKENHI-PROJECT-23590082
[Presentation] Mef/Elf4 transactivation by E2F1 is inhibited by p53.2011
- Author(s)
  M. Suico, M. Taura, R. Fukuda, T. Koga, T. Shuto, T. Sato, S. Morino, S. Okada, H. Kai
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（京都）
- Data Source
  KAKENHI-PROJECT-23590082
[Presentation] 遺伝性腎疾患Alport症候群における癌抑制遺伝子p53の腎病態進行抑制機構の解明2011
- Author(s)
  福田　亮介、小山　皓介、古賀　友紹、甲斐　友佳理、メリーアン　スイコ、首藤　剛、甲斐　広文
- Organizer
  第28回日本薬学会九州支部大会
- Place of Presentation
  福岡大学薬学部（福岡）
- Data Source
  KAKENHI-PROJECT-23590082
[Presentation] The role of HRD1 in intracellular trafficking of ATP binding cassette transporter G5 and G8.2010
- Author(s)
  Suzuki S, Shuto T, Sato T, Takada T, Kaneko M, Suico MA, Koga T, Morino S, Suzuki H, Kai H
- Organizer
  The 3rd International Symposium on Protein Community
- Place of Presentation
  ホテル日航奈良
- Data Source
  KAKENHI-PROJECT-22390015
[Presentation] Posttranslational regulation of ATP binding cassette transporter G5 and G8 by HRD12010
- Author(s)
  Suzuki S, Shuto T, Sato T, Takada T, Kaneko M, Suico MA, Koga T, Morino S, Suzuki H, Kai H
- Organizer
  ASCB 50th annual meeting Philadelphia
- Place of Presentation
  PA, USA
- Data Source
  KAKENHI-PROJECT-22390015
[Presentation] HRD1によるABCトランスポーターABCG5/8の翻訳後発現制御2010
- Author(s)
  鈴木伸悟, 首藤剛, 新堀晶子, 佐藤卓史, 杉山崇, 高田龍平, 金子雅幸, Mary Ann Suico, 古賀友紹, 森野沙緒里, 鈴木洋史, 甲斐広文
- Organizer
  日本薬学会第130回年会
- Place of Presentation
  岡山コンベンションセンター
- Data Source
  KAKENHI-PROJECT-19390045
[Presentation] Posttranslational regulation of ATP binding cassette transporter G5 and G8 by HRD12010
- Author(s)
  Suzuki S, Shuto T, Sato T, Takada T, Kaneko M, Suico MA, Koga T, Morino S, Suzuki H, Kai H
- Organizer
  Global COE-IMEG Joint Summer Retreat Seminar
- Place of Presentation
  ホテルクリーンピア南阿蘇
- Data Source
  KAKENHI-PROJECT-22390015
[Presentation] The endoplasmic reticulum-associated degradation of transthyretin variants is negatively regulated by BiP in mammalian cells2009
- Author(s)
  T.Sato, S.Susuki, M.Miyata, M.Momohara, M.A.Suico, T.Shuto, Y.Ando, H.Kai
- Organizer
  FASEB SUMMER RESEARCH CONFER ENCES, From unfolded proteins in the endoplasmic reticulum to disease
- Place of Presentation
  Vermont, USA
- Data Source
  KAKENHI-PROJECT-19390045
[Presentation] Modified Mild Heat Shock Modality Attenuates Hepatic Ischemia/Reperfusion Injury2009
- Author(s)
  スイコメリーアン
- Organizer
  The 4th International Congress on Stress Responses in Biology and Medicine
- Place of Presentation
  札幌市ガトーキーニグタム札幌市ホテル
- Data Source
  KAKENHI-PROJECT-20790068
[Presentation] The endoplasmic reticulum-associated degradation of transthyretin variants is negatively regulated by BiP2009
- Author(s)
  T.Sato, S.Susuki, M.Miyata, M.Momohara, Y.Sako, M.A.Suico, T.Shuto, H.Kai
- Organizer
  Cell Stress Society International 2009
- Place of Presentation
  Sapporo, Japam
- Data Source
  KAKENHI-PROJECT-19390045
[Presentation] p53 regulates TLR3 expression in human epithelial cell lines2008
- Author(s)
  Mary Ann Suico
- Organizer
  Joint International Symposium on Cell Fate Regulation : Deyelopment, Degeneration and Regeneration in the Central Nervous System
- Place of Presentation
  Rochester, NY, USA
- Year and Date
  2008-07-16
- Data Source
  KAKENHI-PROJECT-20790068
[Presentation] Screening of small compounds to develop endoplasmic reticulum-oriented drug for familial amyloid polyneuropathy.
- Author(s)
  K. Chosa, S. Takaki, R. Yamakawa, Y. Wakita, Y. Teranishi, T. Sato, T. Yokoyama, M. Mizuguchi, M. Suico, T. Shuto, H. Kai
- Organizer
  The 2014 ascb/ifcb Meeting
- Place of Presentation
  Philadelphia（USA）
- Year and Date
  2014-12-06 – 2014-12-10
- Data Source
  KAKENHI-PROJECT-25253012
[Presentation] Podocyte-specific p53 Deletion Promotes Alport Syndrome Progression by Enhancement of Podocyte Proliferation and Migration
- Author(s)
  R. Fukuda, Y. Kai, K. Omachi, K. Motomura, T. Koga, K. Koyama, M. A. Suico, T. Shuto, H. Kai
- Organizer
  The ASN Kidney Week 2014 Annual Meeting
- Place of Presentation
  Philadelphia（USA）
- Year and Date
  2014-11-13 – 2014-11-16
- Data Source
  KAKENHI-PROJECT-26460098
[Presentation] Alport症候群の原因タンパク質COL4A5に注目した病態発症メカニズムの解明
- Author(s)
  大町紘平, 嘉村美里, 寺本啓祐, 福田亮介, Mary Ann Suico, 首藤剛, 甲斐広文
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26460098
[Presentation] The ETS transcription factor Myeloid Elf-1-like Factor (MEF)/Elf-4 is suppressed by E3 ligase MDM2
- Author(s)
  Mary Ann Suico, Rui Miyakita, Kosuke Koyama, Ryosuke Fukuda, Manabu Taura, Tsuyoshi Shuto, Hirofumi Kai
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26460098
[Presentation] 機能未知遺伝子FAM105Aの新規抗炎症制御分子としての可能性追求
- Author(s)
  福田亮介, 横田翼, Mary Ann Suico, 首藤剛, 古賀友昭, 小山皓介 , 甲斐広文
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26460098
[Presentation] 単球系細胞における新規抗炎症分子FAM105Aの同定及び機能解析
- Author(s)
  福田亮介, 横田翼, 古賀友昭, 小山皓介, Mary Ann Suico, 首藤剛, 甲斐広文
- Organizer
  第31回日本薬学会九州支部大会
- Place of Presentation
  第一薬科大学（福岡県福岡市）
- Year and Date
  2014-12-06 – 2014-12-07
- Data Source
  KAKENHI-PROJECT-26460098
[Presentation] Characterization of the Intracellular Behavior of COL4A5 and Clarification of Molecular Mechanism of Alport Syndrome.
- Author(s)
  K. Omachi, M. Kamura, K. Teramoto, R. Fukuda, M. Suico, T. Shuto, H. Kai
- Organizer
  The 2014 ascb/ifcb Meeting
- Place of Presentation
  Philadelphia（USA）
- Year and Date
  2014-12-06 – 2014-12-10
- Data Source
  KAKENHI-PROJECT-26460098
[Presentation] Podocyte-specific p53 Deletion Promotes Alport Syndrome Progression by Enhancement of Podocyte Proliferation and Migration
- Author(s)
  R. Fukuda, Y. Kai, K. Omachi, K. Motomura, T. Koga, K. Koyama, M. A. Suico, T. Shuto, H. Kai
- Organizer
  Pharmacology 2014
- Place of Presentation
  Queen Elizabeth II Conference Centre, London, UK
- Year and Date
  2014-12-16 – 2014-12-18
- Data Source
  KAKENHI-PROJECT-26460098
[Presentation] The endoplasmic reticulum-oriented drug development for familial amyloid polyneuropathy
- Author(s)
  K. Chosa, R. Yamakawa, T. Sato, T. Yokoyama, M. Mizuguchi, M. Suico, T. Shuto, H. Kai
- Organizer
  WCP2014 17th World Congress of Basic & Clinical Pharmacology
- Place of Presentation
  Cape Town（South Africa）
- Year and Date
  2014-07-13 – 2014-07-18
- Data Source
  KAKENHI-PROJECT-25253012
[Presentation] 小胞体品質管理機構を標的とした家族性アミロイドポリニューロパチー（FAP）の新規治療薬開発
- Author(s)
  帖佐圭佑, 高木舜, 山川瑠斐子, 脇田有梨子, 寺西ゆり子, 佐藤卓史, 横山武司, 水口峰之, Mary Ann Suico , 首藤剛, 甲斐広文
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25253012
[Presentation] 遺伝性腎疾患の発症機構に関わる新たな分子標的
- Author(s)
  Mary Ann Suico, 福田亮介, 首藤剛, 甲斐広文
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-26460098
[Presentation] 腎疾患におけるp53の病態生理学的役割と新たな病態進行抑制薬の開発に向けて
- Author(s)
  甲斐広文, 福田亮介, 大町紘平, Mary Ann Suico, 首藤剛
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-26460098
[Presentation] Alport症候群の原因タンパク質COL4A5に注目した病態発症メカニズムの解明
- Author(s)
  大町紘平, 嘉村美里, 寺本啓祐, 福田亮介, Mary Ann Suico, 首藤剛, 甲斐広文
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-26460098
[Presentation] バーチャルおよびハイスループットスクリーニングを用いた家族性アミロイドポリニューロパチーの新規治療薬の開発
- Author(s)
  帖佐圭佑, 高木舜, 脇田有梨子, 寺西ゆり子, 山川瑠斐子, 佐藤卓史, 横山武司, 水口峰之, Mary Ann Suico , 首藤剛, 甲斐広文
- Organizer
  第8回次世代を担う若手医療薬科学シンポジウム
- Place of Presentation
  熊本大学薬学部（熊本県熊本市）
- Year and Date
  2014-11-15 – 2014-11-16
- Data Source
  KAKENHI-PROJECT-25253012

1. SHUTO Ysuyoshi (80333524)

# of Collaborated Projects: 6 results

# of Collaborated Products: 104 results
2. KAI Hirofumi (30194658)

# of Collaborated Projects: 5 results

# of Collaborated Products: 105 results
3. 池水信二 (60333522)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. KOTANI Shunsuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 荒木栄一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 近藤龍也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 金子雅幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SUICO MARY ANN SOTEN スイコ メリー・アン・ソテン

SUICO Mary Ann Soten スイコ メリー・アン・ソテン

MARY ANN Suico メリーアン スイコ

ANN SOTEN Suico mary アン・ソテン スイコ・メリー

スイコ メリーアン・ソテン スイコ メリー・アン・ソテン

SUICO MARY Ann Soten スイコ・メリー アン・ソテン

スイコ メリー・アン・ソテン スイコ メリー アンソテン

SUICO Mary Ann スイコ メアリー アン

メリー・アン スイコ メリー・アン スイコ

Research Projects

Research Products

Co-Researchers

Therapeutic screening and molecular basis for Congenital Nephrotic Syndrome of the Finish type (CNF)Principal Investigator

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Advanced research on the original drug discovery platform for hereditary intractable Alport syndrome

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Molecular basis on drug development targeting causative molecules of genetic nephritis Alport syndromePrincipal Investigator

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Establishment of research platform for the development of renal precision medicine

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Review Section

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Molecular basis and clinical implication of podocyte MEF-p53 network in CKD pathogenesisPrincipal Investigator

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The role of transcription factors p53 and MEF in a mouse model of chronic kidney disease (CKD)Principal Investigator

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Drug discovery for Familial amyloid polyneuropathy (FAP), an incurable hereditary disease

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Regulatory mechanism of expression of ETS transcription factor Myeloid elf-1-like factor (MEF) by tumor suppressorsPrincipal Investigator

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Drug development on protein misfolding diseases

Principal Investigator

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Molecular Basis of the regulation of ETS transcription factor MEF expression by tumor suppressor gene p53Principal Investigator

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Therapeutic principles on protein misfolding diseases

Principal Investigator

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IL-2/IL-2R複合体形成機構の構造生物学的研究

Principal Investigator

SUICO MARY ANN SOTEN スイコメリー・アン・ソテン

SUICO Mary Ann Soten スイコメリー・アン・ソテン

MARY ANN Suico メリーアンスイコ

ANN SOTEN Suico mary アン・ソテンスイコ・メリー

スイコメリーアン・ソテンスイコメリー・アン・ソテン

SUICO MARY Ann Soten スイコ・メリーアン・ソテン

スイコメリー・アン・ソテンスイコメリーアンソテン

SUICO Mary Ann スイコメアリーアン

メリー・アンスイコメリー・アンスイコ