SHIBUYA MIHOKO 澁谷美穂子

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SHIBUYA Mihoko 澁谷美穂子

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Researcher Number	20366363
Affiliation (Current)	2025: 東京大学, 医学部附属病院, 助教
Affiliation (based on the past Project Information) *help	2012 – 2015: 東京大学, 医学部附属病院, 助教 2011: 東京大学, 医学部附属病院, 特任臨床医
Review Section/Research Field	Principal Investigator 膠原病・アレルギー・感染症内科学 Except Principal Investigator 膠原病・アレルギー・感染症内科学
Keywords	Principal Investigator 抗原特異性 / 自己反応性T細胞 / 免疫学 / エピトープスプレディング / 膠原病学 Except Principal Investigator 細胞・組織 / 生体分子 / 組織・細胞 / 免疫学 / 内科 / ゲノム

Development of rheumatoid arthritis-directed human immunology
- Principal Investigator
  
  YAMAMOTO KAZUHIKO
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  The University of Tokyo
Studies on the mechanism of the tolerance break ofautoimmunity-Analysis of the T cells activation mechanism by epitope spreading-Principal Investigator
- Principal Investigator
  
  SHIBUYA Mihoko
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  The University of Tokyo

All 2015 2013 2012 2011

All Journal Article Presentation

[Journal Article] A new T-cell activation mode for suboptimal doses of antigen under the full activation of T cells with different specificity.2015
- Author(s)
  Shibuya M, Fujio K, Shoda H, Okamura T, Okamoto A, Sumitomo S, Yamamoto K.
- Journal Title
  
  Europian Journal of Immunology
  
  Volume: in press Issue: 6 Pages: 1643-53
- DOI
  10.1002/eji.201444965
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461493, KAKENHI-PROJECT-23229007
[Journal Article] Autoantigen BiP-derived HLA-DR4 epitopes differentially recognized by effector and regulatory T cells in rheumatoid arthritis.2015
- Author(s)
  Shoda H, Fujio K, Sakurai K, Ishigaki K, Nagafuchi Y, Shibuya M, Sumitomo S, Okamura T, Yamamoto K
- Journal Title
  
  Arthritis and Rheumatology
  
  Volume: in press Issue: 5 Pages: 1171-81
- DOI
  10.1002/art.39054
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23229007, KAKENHI-PROJECT-25461493, KAKENHI-PROJECT-26461462
[Journal Article] Transcription factor early growth response 3 is associated with the TGF-β1 expression and the regulatory activity of CD4-positive T cells in vivo.2013
- Author(s)
  Sumitomo S, Fujio K, Okamura T, Morita K, Ishigaki K, Suzukawa K, Kanaya K, Kondo K, Yamasoba T, Furukawa A, Kitahara N, Shoda H, Shibuya M, Okamoto A, Yamamoto K.
- Journal Title
  
  J Immunol
  
  Volume: 191 Issue: 5 Pages: 2351-9
- DOI
  10.4049/jimmunol.1202106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23229007, KAKENHI-PROJECT-24390252, KAKENHI-PROJECT-24790990, KAKENHI-PROJECT-25461470, KAKENHI-PROJECT-25461493, KAKENHI-PROJECT-25670459, KAKENHI-PROJECT-25860804
[Presentation] Without cognate antigens T cell proliferation induced by 'Extended antigen presentation' was not observed2012
- Author(s)
  Mihoko Shibuya
- Organizer
  第8回国際自己免疫疾患学会議
- Place of Presentation
  Palaciode Exposiciones y Congresos de Granada、スペイン
- Year and Date
  2012-05-12
- Data Source
  KAKENHI-PROJECT-23791103
[Presentation] WITHOUT COGNATE ANTIGENS T CELL PROLIFERATION INDUCED BY ‘EXTENDED ANTIGEN PRESENTATION’ WAS NOT OBSERVED.2012
- Author(s)
  澁谷美穂子
- Organizer
  第8回国際自己免疫疾患学会議
- Place of Presentation
  Palacio de Exposiciones y Congresos de Granada、スペイン
- Data Source
  KAKENHI-PROJECT-23791103
[Presentation] 特異抗原が存在しないと拡張抗原によるT細胞の活性化は起こらない2011
- Author(s)
  澁谷美穂子
- Organizer
  日本免疫学会
- Place of Presentation
  幕張メッセ
- Year and Date
  2011-11-29
- Data Source
  KAKENHI-PROJECT-23791103
[Presentation] 特異抗原が存在しないと拡張抗原によるT細胞の活性化は起こらない2011
- Author(s)
  澁谷美穂子
- Organizer
  日本免疫学会
- Place of Presentation
  幕張メッセ(千葉県)
- Data Source
  KAKENHI-PROJECT-23791103

1. YAMAMOTO KAZUHIKO (80191394)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
2. OKAMURA TOMOHISA (10528996)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
3. SHODA HIROFUMI (20529036)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. SUMITOMO SHUJI (20392996)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. IWASAKI YUKIKO (30592935)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 岡本明子 (40431861)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

SHIBUYA MIHOKO 澁谷 美穂子

SHIBUYA Mihoko 澁谷 美穂子

Research Projects

Research Products

Co-Researchers

Development of rheumatoid arthritis-directed human immunology

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on the mechanism of the tolerance break ofautoimmunity-Analysis of the T cells activation mechanism by epitope spreading-Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] A new T-cell activation mode for suboptimal doses of antigen under the full activation of T cells with different specificity.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Autoantigen BiP-derived HLA-DR4 epitopes differentially recognized by effector and regulatory T cells in rheumatoid arthritis.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Transcription factor early growth response 3 is associated with the TGF-β1 expression and the regulatory activity of CD4-positive T cells in vivo.2013

Author(s)

Journal Title

DOI

Data Source

[Presentation] Without cognate antigens T cell proliferation induced by 'Extended antigen presentation' was not observed2012

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] WITHOUT COGNATE ANTIGENS T CELL PROLIFERATION INDUCED BY ‘EXTENDED ANTIGEN PRESENTATION’ WAS NOT OBSERVED.2012

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 特異抗原が存在しないと拡張抗原によるT細胞の活性化は起こらない2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 特異抗原が存在しないと拡張抗原によるT細胞の活性化は起こらない2011

Author(s)

Organizer

Place of Presentation

Data Source

SHIBUYA MIHOKO 澁谷美穂子

SHIBUYA Mihoko 澁谷美穂子