Mizuochi Tatsuki 水落建輝

… Alternative Names

水落建輝ミズオチタツキ

MIZUOCHI Tatsuki 水落建輝

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Researcher Number	20368921
Other IDs
Affiliation (Current)	2025: 久留米大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2023: 久留米大学, 医学部, 主任教授 2021 – 2023: 久留米大学, 医学部, 准教授 2017 – 2020: 久留米大学, 医学部, 講師 2015 – 2016: 久留米大学, 医学部, 助教 2010 – 2012: 久留米大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 52050:Embryonic medicine and pediatrics-related / Pediatrics
Keywords	Principal Investigator 小児 / バイオマーカー / 肝臓病 / オキシステロール / 遺伝子 / 病因遺伝子 / 血清マーカー / 自己免疫性肝疾患 / 肝不全 / 胆道閉鎖症 … More / 急性肝不全 / 肝疾患 / 移植・再生医療 / 内科 / 酵素 / 遺伝学 Less

Exploring biomarker and disease-associated gene in pediatric patients with autoimmune liver diseasePrincipal Investigator
- Principal Investigator
  
  Mizuochi Tatsuki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Kurume University
Oxysterol as a biomarker for pediatric acute liver failurePrincipal Investigator
- Principal Investigator
  
  Mizuochi Tatsuki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Kurume University
Oxysterols in children: potential biomarker for pediatric liver diseasePrincipal Investigator
- Principal Investigator
  
  Mizuochi Tatsuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kurume University
Establishment of genetic diagnosis and medical treatment in patients with inborn errors of bile acid metabolism: Aiming to prevent liver transplantationPrincipal Investigator
- Principal Investigator
  
  MIZUOCHI Tatsuki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  Kurume University

All 2022 2021 2020 2018 2013 2012 2011 2010 Other

All Journal Article Presentation Other

[Journal Article] A Japanese prospective multicenter study of urinary oxysterols in biliary atresia2021
- Author(s)
  Konishi K, Mizuochi T, Takei H, Yasuda R, Sakaguchi H, Ishihara J, Takaki Y, Kinoshita M, Hashizume N, Fukahori S, Shoji H, Miyano G, Yoshimaru K, Matsuura T, Sanada Y, Tainaka T, Uchida H, Kubo Y, Tanaka H, Sasaki H, Murai T, Fujishiro J, Yamashita Y, Nio M, Nittono H, Kimura A
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 4986-4986
- DOI
  10.1038/s41598-021-84445-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K16941, KAKENHI-PROJECT-18K07833
[Journal Article] Urinary and serum oxysterols in children: developmental pattern and potential biomarker for pediatric liver disease.2020
- Author(s)
  Takaki Y, Mizuochi T, Takei H, Eda K, Konishi KI, Ishihara J, Kinoshita M, Hashizume N, Yamashita Y, Nittono H, Kimura A.
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 6752-6752
- DOI
  10.1038/s41598-020-63758-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07833
[Journal Article] Oxysterol changes along with cholesterol and vitamin D changes in adult phenylketonuric patients diagnosed by newborn mass-screening.2013
- Author(s)
  Nagasaka H, Okano Y, Kimura A, Mizuochi T, Sanayama Y, Takatani T, Nakagawa S, Hasegawa E, Hirano K, Mochizuki H, Ohura T, Ishige-Wada M, Usui H, Yorifuji T, Tsukahara H, Hirayama S, Ohtake A, Yamato S, Miida T.
- Journal Title
  
  Clin Chim Acta.
  
  Volume: 416 Pages: 54-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791008
[Journal Article] Two neonatal cholestsis patients with mutations in the SRD5B1 (AKR1D1) gene: diagnosis and bile acid profiles during chenodeoxycholic acid treatment.2013
- Author(s)
  Seki, Y., Mizuochi, T., Kimura, A., Takahashi T., Ohtake, A., Hayashi, S., Morimura, T., Ohno, Y., Hoshina, T., Ihara, K., Takei, H., Nittono H., Kurosawa T., Homma K., Hasegawa T., Matsuishi T.
- Journal Title
  
  J Inherit Metab Dis
  
  Volume: 36(3) Issue: 3 Pages: 565-573
- DOI
  10.1007/s10545-012-9526-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591144, KAKENHI-PROJECT-22791008, KAKENHI-PROJECT-24591531, KAKENHI-PROJECT-25461568
[Journal Article] Neonatal cholestasis with increased3β-monohydroxy-Δ bile acids inserum and urine: not necessarilyprimary oxysterol7α hydroxylase deficiency.2012
- Author(s)
  Kimura A, Nittono H, Mizuochi T,Ueki I, Kurosawa T, Muto A, Takei H.
- Journal Title
  
  Clin Chim Acta.
  
  Volume: 413(19-20) Issue: 19-20 Pages: 1700-4
- DOI
  10.1016/j.cca.2012.05.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791008
[Journal Article] Detection of Δ4-3-oxo-steroid 5β-reductase deficiency by LC-ESI-MS/MS measurement of urinary bile acids.2012
- Author(s)
  Muto A, Takei H, Unno A, Murai T, Kurosawa T, Ogawa S, Iida T, Ikegawa S, Mori J, Ohtake A, Hoshina T, Mizuochi T, Kimura A, Hofmann AF, Hagey LR, Nittono H.
- Journal Title
  
  J Chromatogr B Analyt Technol Biomed Life Sci.
  
  Volume: 900 Pages: 24-31
- DOI
  10.1016/j.jchromb.2012.05.023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791008
[Journal Article] 先天性胆汁酸代謝異常.2011
- Author(s)
  水落建輝,木村昭彦
- Journal Title
  
  小児内科
  
  Volume: 43 Pages: 1042-1045
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791008
[Journal Article] Successful heterozygous living donor liver transplantation for an oxysterol 7α-hydroxylase deficiency in a Japanese patient.2011
- Author(s)
  Mizuochi T, Kimura A, Suzuki M, Ueki I, Takei H, Nittono H, Kakiuchi T, Shigeta T, Sakamoto S, Fukuda A, Nakazawa A, Shimizu T, Kurosawa T, Kasahara M.
- Journal Title
  
  Liver Transpl
  
  Volume: 17(9) Issue: 9 Pages: 1059-65
- DOI
  10.1002/lt.22331
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791008
[Journal Article] 先天性胆汁酸代謝異常2011
- Author(s)
  水落建輝, 他
- Journal Title
  
  小児内科2011;43:1042-1045
  
  Volume: 43 Pages: 1042-1045
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791008
[Journal Article] Zinc Monotherapy From Time of Diagnosis for Young Pediatric Patients With Presymptomatic Wilson Disease2011
- Author(s)
  Mizuochi Tatsuki, et al
- Journal Title
  
  J Pediatric Gastroenterology and Nutrition
  
  Volume: 53 Pages: 365-367
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791008
[Journal Article] Successful Heterozygous Living Donor Liver Transplantation for an Oxysterol7α-Hydroxylase Deficiency in a Japanese Patient2011
- Author(s)
  Mizuochi Tatsuki, et al
- Journal Title
  
  Liver Transplantation
  
  Volume: 17 Pages: 1059-1065
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791008
[Journal Article] 胆汁酸代謝異常症-診断へのアプローチと1次胆汁酸療法-.2010
- Author(s)
  水落建輝,木村昭彦
- Journal Title
  
  小児科臨床
  
  Volume: 63 Pages: 2081-2087
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791008
[Journal Article] 胆汁酸代謝異常症-診断へのアプローチと1次胆汁酸療法-2010
- Author(s)
  水落建輝
- Journal Title
  
  小児科臨床
  
  Volume: 63巻 Pages: 2081-2087
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791008
[Journal Article] Molecular Genetic and Bile Acid Profiles in Two Japanese Patients With 3β -Hydroxy-Δ^5-C_27-Steroid Dehydrogenase/Isomerase Deficiency.2010
- Author(s)
  Mizuochi Tatsuki
- Journal Title
  
  Pediatric Research
  
  Volume: 68巻 Pages: 258-263
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791008
[Journal Article] Molecular genetics and bile acid profiles of 3beta-hydroxy-delta5-C27-steroid dehydrogenase/isomerase deficiency in 2 Japanise patients.2010
- Author(s)
  Mizuochi T., Kimura A., Ueki I., Takahashi T., Hashimoto T., Takao A., Seki Y., Takei H., Nittono H., Kurosawa T., Matsuishi T.
- Journal Title
  
  Pediatr Res
  
  Volume: 68(3) Pages: 258-263
- DOI
  10.1203/00006450-201011001-00505
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591144, KAKENHI-PROJECT-22791008
[Presentation] 小児自己免疫性肝疾患の新規バイオマーカーと病因遺伝子の探索研究（JPAILD Study）の立ち上げ2022
- Author(s)
  水落建輝，津村直弥，加藤　健，安田亮輔，西小森隆太，小原　収，JPAILD Study Investigators.
- Organizer
  第38回日本小児肝臓研究会
- Data Source
  KAKENHI-PROJECT-21K07832
[Presentation] 胆道閉鎖症におけるオキシステロールのバイオマーカーとしての可能性2020
- Author(s)
  水落建輝
- Organizer
  第47回日本小児栄養消化器肝臓学会
- Invited
- Data Source
  KAKENHI-PROJECT-18K07833
[Presentation] オキシステロールは小児急性肝不全のバイオマーカーとして有用か？～A Pilot Study～2018
- Author(s)
  水落建輝
- Organizer
  第54回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-18K07833
[Presentation] Molecular genetics in Asian patients with inborn errors of bile acid synthesis.2012
- Author(s)
  Tatsuki Mizuochi.
- Organizer
  The 4th World Congress of Pediatric Gastroenterology, Hepatology and Nutrition. Oral Presentation.
- Place of Presentation
  Taipei, Taiwan
- Data Source
  KAKENHI-PROJECT-22791008
[Presentation] 分野別シンポジウム「代謝性肝疾患の最前線」　胆汁酸代謝異常症2012
- Author(s)
  水落建輝
- Organizer
  第115回日本小児科学会学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22791008
[Presentation] 胆汁酸代謝異常症.2012
- Author(s)
  水落建輝
- Organizer
  第115回日本小児科学会学術集会分野別シンポジウム「代謝性肝疾患の最前線」.
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22791008
[Presentation] Molecular genetics in Asian patients with inborn errors of bile acid synthesis2012
- Author(s)
  Mizuochi Tatsuki
- Organizer
  The 4th World Congress of Pediatric Gastroenterology, Hepatology and Nutrition
- Place of Presentation
  Taipei, Taiwan
- Data Source
  KAKENHI-PROJECT-22791008
[Presentation] 3β-HSD欠損症の邦人2例に対する分子遺伝学的解析と胆汁酸プロファイル.第39回日本小児栄養消化器肝臓学会・2012
- Author(s)
  水落建輝
- Organizer
  第29回日本小児肝臓研究会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22791008
[Presentation] 3β-HSD欠損症の邦人2例に対する分子遺伝学的解析と胆汁酸プロファイル2012
- Author(s)
  水落建輝
- Organizer
  第39回日本小児栄養消化器肝臓学会・第29回日本小児肝臓研究会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22791008
[Presentation] Oxysterol7α欠損症に対する遺伝子解析と生体肝移植-世界初の肝移植救命例の報告-.2011
- Author(s)
  水落建輝
- Organizer
  第114回日本小児科学会学術集会.
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22791008
[Presentation] Oxysterol 7α欠損症に対する遺伝子解析と生体肝移植-世界初の肝移植救命例の報告-2011
- Author(s)
  水落建輝
- Organizer
  第114回日本小児科学会学術集会
- Place of Presentation
  グランドプリンス新高輪(東京)
- Data Source
  KAKENHI-PROJECT-22791008
[Presentation] 胆汁酸代謝異常症.2011
- Author(s)
  水落建輝.
- Organizer
  第53回日本先天代謝異常学会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-22791008
[Presentation] 肝内胆汁うっ滞に対するリファンピシン作用機序の解析2011
- Author(s)
  水落建輝
- Organizer
  第28回日本小児肝臓研究会
- Place of Presentation
  つくば国際会議場(茨城)
- Year and Date
  2011-07-16
- Data Source
  KAKENHI-PROJECT-22791008
[Presentation] 胆汁酸代謝異常症2011
- Author(s)
  水落建輝
- Organizer
  第53回日本先天代謝異常学会
- Place of Presentation
  幕張メッセ(千葉)
- Data Source
  KAKENHI-PROJECT-22791008
[Presentation] 新生児肝炎の鑑別疾患としての胆汁酸代謝異常症-本邦における診断法の確立-2010
- Author(s)
  水落建輝
- Organizer
  第113回日本小児科学会学術集会
- Place of Presentation
  岩手
- Data Source
  KAKENHI-PROJECT-22791008
[Presentation] 新生児肝炎の鑑別疾患としての胆汁酸代謝異常症-本邦における診断法の確立-.2010
- Author(s)
  水落建輝
- Organizer
  第113回日本小児科学会学術集会.
- Place of Presentation
  岩手
- Data Source
  KAKENHI-PROJECT-22791008
[]

1. KIMURA Akihiko (00211201)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 西小森隆太 (70359800)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. NITTONO Hiroshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 安田亮輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 高橋和之

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
6. 松石豊次郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Mizuochi Tatsuki 水落 建輝

水落 建輝 ミズオチ タツキ

MIZUOCHI Tatsuki 水落 建輝

Research Projects

Research Products

Co-Researchers

Exploring biomarker and disease-associated gene in pediatric patients with autoimmune liver diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Oxysterol as a biomarker for pediatric acute liver failurePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Oxysterols in children: potential biomarker for pediatric liver diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of genetic diagnosis and medical treatment in patients with inborn errors of bile acid metabolism: Aiming to prevent liver transplantationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] A Japanese prospective multicenter study of urinary oxysterols in biliary atresia2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Urinary and serum oxysterols in children: developmental pattern and potential biomarker for pediatric liver disease.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Oxysterol changes along with cholesterol and vitamin D changes in adult phenylketonuric patients diagnosed by newborn mass-screening.2013

Author(s)

Journal Title

Data Source

[Journal Article] Two neonatal cholestsis patients with mutations in the SRD5B1 (AKR1D1) gene: diagnosis and bile acid profiles during chenodeoxycholic acid treatment.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Neonatal cholestasis with increased3β-monohydroxy-Δ bile acids inserum and urine: not necessarilyprimary oxysterol7α hydroxylase deficiency.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Detection of Δ4-3-oxo-steroid 5β-reductase deficiency by LC-ESI-MS/MS measurement of urinary bile acids.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 先天性胆汁酸代謝異常.2011

Author(s)

Journal Title

Data Source

[Journal Article] Successful heterozygous living donor liver transplantation for an oxysterol 7α-hydroxylase deficiency in a Japanese patient.2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 先天性胆汁酸代謝異常2011

Author(s)

Journal Title

Data Source

[Journal Article] Zinc Monotherapy From Time of Diagnosis for Young Pediatric Patients With Presymptomatic Wilson Disease2011

Author(s)

Journal Title

Data Source

[Journal Article] Successful Heterozygous Living Donor Liver Transplantation for an Oxysterol7α-Hydroxylase Deficiency in a Japanese Patient2011

Author(s)

Journal Title

Data Source

Mizuochi Tatsuki 水落建輝

水落建輝ミズオチタツキ

MIZUOCHI Tatsuki 水落建輝

[Presentation] 分野別シンポジウム「代謝性肝疾患の最前線」　胆汁酸代謝異常症2012