• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

ASAGIRI MASATAKA  朝霧 成挙

ORCIDConnect your ORCID iD *help
… Alternative Names

ASAGIRI Masataka  朝霧 成挙

Less
Researcher Number 20372435
Other IDs
Affiliation (Current) 2025: 山口大学, 大学院医学系研究科, 教授
Affiliation (based on the past Project Information) *help 2019 – 2024: 山口大学, 大学院医学系研究科, 教授
2016: 名古屋市立大学, 薬学研究科(研究院), 准教授
2014 – 2016: 京都大学, 医学研究科, 特定准教授
2012 – 2014: 京都大学, 医学(系)研究科(研究院), 准教授
2012: 京都大学, 医学研究科, 特定准教授 … More
2007: Tokyo Medical and Dental University, Graduate School of Medicine, COE Research Associate Professor (Junior)
2007: 東京医科歯科大学, 大学院・医歯学総合研究科, 特任講師
2006 – 2007: 医科歯科大, 医歯(薬)学総合研究科
2006: Tokyo Medical and Dental University, Graduate School, Assistant professor, 大学院医歯学総合研究科, 特任講師
2005: 東京医科歯科大学, 大学院・医歯学総合研究科, 特任助手
2005: 東京医科歯科大学, 大学院・医歯学総合研究科・COE拠再形成特任助手
2005: 東京医科歯科大学, 大学院医歯学総合研究科, COE拠点形成特任教員
2005: 東京医科歯科大学, 大学院医歯学総合研究科, 特任助手
2004: 東京医科歯科大学, 大学院・医歯学総合研究科, COE特任助手
2004: Tokyo Medical and Dental University, Graduate School, Assistant Professor for COE project, 大学院医歯学総合研究科, COE特任助手 Less
Review Section/Research Field
Principal Investigator
Orthopaedic surgery / Basic Section 56020:Orthopedics-related / Functional basic dentistry / Experimental pathology
Except Principal Investigator
Orthopaedic surgery / Basic Section 56060:Ophthalmology-related / Basic Section 56020:Orthopedics-related / Basic Section 48030:Pharmacology-related / Experimental pathology / 膠原病・アレルギー・感染症内科学
Keywords
Principal Investigator
関節リウマチ / 炎症 / 組織破壊 / 歯周病 / 破骨細胞 / 自己免疫 / 免疫学 / 骨代謝 / 組織再構築 / 骨破壊 … More / 細胞外マトリクス / 細胞変容 / 転写因子 / 病理学 / サイトカイン / 自然免疫 / 骨疾患 / 骨免疫 / 持続炎症 / 糖尿病 / Osteoimmunology / Osteoporosis / Transcription factor / Osteoclast / Periodontitis / Rheumatoid arthritis / Bone destruction / Bone disease / 骨免疫学 / 遺伝子改変動物 / 組織変性 / 組織恒常性 / システム生物学 / 炎症性細胞変容 / Toll-like receptor (TLR) / IκBζ / Th17細胞 / 樹状細胞 / プロテアーゼ / Toll-like receptor(TLR) / カテプシン / BH3 / アポトーシス / 創薬 … More
Except Principal Investigator
破骨細胞 / 骨代謝 / 骨免疫学 / 免疫学 / 骨芽細胞 / 転写因子 / 関節リウマチ / ノックアウトマウス / 骨粗鬆症 / 脈絡膜新生血管 / 樹状細胞 / 鯨油 / オメガ3脂肪酸 / 難治性のぶどう膜炎 / 治癒促進 / 骨折 / 液液相分離 / パラスペックル / 液液相分離体 / PDZRN3 / 心筋細胞 / 細胞分化 / T cell / rheumatoid arthritis / osteoporosis / immunology / transcription factor / kinase / bone metabolism / osteoclast / レトロウイルスベクター / MAPキナーゼ / コンディショナルノックアウトマウス / 質量分析 / TAK1 / コンディショナルノックアウト / ホスファターゼ / T細胞 / キナーゼ / Metastasis / Tumor / Calcium binding protein / Neovasucularization / Vascular endothelial cell / 転移 / 癌 / カルシウム結合蛋白質 / 血管新生 / 血管内皮細胞 / 細胞・組織 / 生理学 / シグナル伝達 / 整形外科学 / 骨代謝学 / プロテオーム / トランスクリプトーム / Th17細胞 / 骨細胞 / リンパ球 / 疾患モデル / 自己免疫 / 骨疾患 / 免疫グロブリン様受容体 / サイトカイン / ヘルパーT細胞 / 面沖グロブリン様受容体 / NFATc1 / 大理石骨病 / 破骨細胞分化因子 Less
  • Research Projects

    (16 results)
  • Research Products

    (68 results)
  • Co-Researchers

    (22 People)
  •  破骨細胞の新たな調節メカニズム:炎症と細胞外マトリクスの相互作用の解明Principal Investigator

    • Principal Investigator
      朝霧 成挙
    • Project Period (FY)
      2024 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Yamaguchi University
  •  Interaction of PTH and Wnt/beta-catenin signaling on impaired fracture healing with aging

    • Principal Investigator
      油形 公則
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Yamaguchi University
  •  鯨油由来の脂肪酸成分による免疫細胞誘導療法を目指した眼炎症抑制療法の開発

    • Principal Investigator
      柳井 亮二
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56060:Ophthalmology-related
    • Research Institution
      The University of Tokushima
  •  The role of PDZRN3 in the regulation of cardiomyocyte differentiation

    • Principal Investigator
      Honda Takeshi
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 48030:Pharmacology-related
    • Research Institution
      Kurume University
      Yamaguchi University
  •  Mechanisms of Inflammatory Osteoclast Formation Mediated by Inflammatory and Necrotic Cell Factors and Extracellular Matrix InteractionsPrincipal Investigator

    • Principal Investigator
      ASAGIRI Masataka
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Yamaguchi University
  •  Understanding the Formation and Activation Mechanism of Inflammatory OsteoclastsPrincipal Investigator

    • Principal Investigator
      ASAGIRI Masataka
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Yamaguchi University
      Kyoto University
  •  Signaling dynamics of inflammatory cellular responses in the activation of pothogenic bone destruction programPrincipal Investigator

    • Principal Investigator
      ASAGIRI MASATAKA
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Functional basic dentistry
    • Research Institution
      Kyoto University
  •  Towards an integrated understandings of the inflammatory tissue remodeling in the pathogenesis of rheumatoid arthritisPrincipal Investigator

    • Principal Investigator
      ASAGIRI Masataka
    • Project Period (FY)
      2012 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (A)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Nagoya City University
      Kyoto University
  •  炎症性破骨細胞の同定とその特異的プロテアーゼに着目した骨破壊防御法の開発Principal Investigator

    • Principal Investigator
      高柳 広, 朝霧 成挙
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Experimental pathology
    • Research Institution
      Tokyo Medical and Dental University
  •  Transcriptional regulation of osteoclastogenesisPrincipal Investigator

    • Principal Investigator
      ASAGIRI Masataka
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Tokyo Medical and Dental University
  •  破骨細胞を制御する免疫グロブリン様受容体リガンドの同定とその機能解析

    • Principal Investigator
      佐藤 浩二郎
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Saitama Medical University
      Tokyo Medical and Dental University
  •  硬組織疾患におけるp53およびアポトーシス誘導遺伝子Noxaの役割Principal Investigator

    • Principal Investigator
      朝霧 成挙
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Functional basic dentistry
    • Research Institution
      Tokyo Medical and Dental University
  •  Osteoimmunology

    • Principal Investigator
      TAKAYANAGI Hiroshi
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Creative Scientific Research
    • Research Institution
      Tokyo Medical and Dental University
  •  キメラマウスを用いた破骨細胞分化におけるNFATc1の役割の研究

    • Principal Investigator
      TAKAYANAGI Hiroshi
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Tokyo Medical and Dental University
  •  Analysis of regulatory mechanisms of bone metabolism utilizing TAK1-conditional knockout mice

    • Principal Investigator
      SATO Kojiro
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Saitama Medical University
      Tokyo Medical and Dental University
  •  Pathophysiological Role of the Association between Metastasis-Associated Protein, S100A4 and Angiogenesis-Related Protein, MetAP2

    • Principal Investigator
      SATOH Hitoshi, 森 茂郎
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      The University of Tokyo

All 2022 2015 2014 2013 2008 2007 2006 2005 Other

All Journal Article Presentation Patent

  • [Journal Article] Dantrolene, a stabilizer of the ryanodine receptor, prevents collagen-induced arthritis.2022

    • Author(s)
      58)Nawata T, Sakai H, Honda T, Otsuka M, Fujita H, Uchinoumi H, Kobayashi S, Yamamoto T, Asagiri M, Yano M.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 624 Pages: 141-145

    • DOI

      10.1016/j.bbrc.2022.07.111

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K06803, KAKENHI-PROJECT-21K08054, KAKENHI-PROJECT-21K08128, KAKENHI-PROJECT-20H03677
  • [Journal Article] Inhibition of MMP-2-Mediated Mast Cell Invasion by NF-κB Inhibitor DHMEQ in Mast Cells2015

    • Author(s)
      Noma N, Asagiri M, Takeiri M, Ohmae S, Takemoto K, Iwaisako K, Minato N, Maeda-Yamamoto M, Simizu S, Umezawa K
    • Journal Title

      Int Arch Allergy Immunol

      Volume: 166 Issue: 2 Pages: 84-90

    • DOI

      10.1159/000371419

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-14J06672, KAKENHI-PROJECT-24659822, KAKENHI-PROJECT-24689056, KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111008
  • [Journal Article] Migration of splenic lymphocytes promotes liver fibrosis through modification of T helper cytokine balance in mice2015

    • Author(s)
      Tanabe K, Taura K, Koyama Y, Yamamoto G, Nishio T, Okuda Y, Nakamura K, Toriguchi K, Takemoto K, Yamanaka K, Iwaisako K, Seo S, Asagiri M, Hatano E, Uemoto S.
    • Journal Title

      Journal of Gastroenterology

      Volume: in press Issue: 10 Pages: 1054-1068

    • DOI

      10.1007/s00535-015-1054-3

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659822, KAKENHI-PROJECT-24689056, KAKENHI-PROJECT-26461909, KAKENHI-PROJECT-15K15495
  • [Journal Article] Necrostatin-1 protects against reactive oxygen species (ROS)-induced hepatotoxicity in acetaminophen-induced acute liver failure.2014

    • Author(s)
      Takemoto K, Hatano E, Iwaisako K, Takeiri M, Noma N, Ohmae S, Toriguchi K, Tanabe K, Tanaka H, Seo S, Taura K, Machida K, Takeda N, Saji S, Uemoto S, Asagiri M.
    • Journal Title

      FEBS Open Bio

      Volume: 4 Issue: 1 Pages: 777-787

    • DOI

      10.1016/j.fob.2014.08.007

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-14J06672, KAKENHI-PROJECT-24659822, KAKENHI-PROJECT-24689056, KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-26461909
  • [Journal Article] Origin of myofiblasts in the fibrotic liver in mice2014

    • Author(s)
      K.Iwaisako, C.Jiang, M.Zhang, M.Cong, T.J.Moore-Morris, T.J.Park, X.Liu, J.Xu, P.Wang, Y-H.Paik, F.Meng, M.Asagiri, L.A.Murray, A.F.Hofmann, T.Iida, C.K.Glass, D.A.Brenner, T.Kisseleva
    • Journal Title

      Proc. Natl. Acad. Sci. USA.

      Volume: 111 Issue: 32

    • DOI

      10.1073/pnas.1400062111

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24550107, KAKENHI-PROJECT-24659822, KAKENHI-PROJECT-24689056, KAKENHI-PROJECT-26461909
  • [Journal Article] Strategies to Detect Hepatic Myofibroblasts in Liver Cirrhosis of Different Etiologies2014

    • Author(s)
      Iwaisako K, Taura K, Koyama Y, Takemoto K, Asagiri M.
    • Journal Title

      Current Pathobiology Reports

      Volume: 2 Issue: 4 Pages: 209-215

    • DOI

      10.1007/s40139-014-0057-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659822, KAKENHI-PROJECT-24689056
  • [Journal Article] Generation of a mouse model with down-regulated U50 snoRNA (SNORD50) expression and its organ-specific phenotypic modulation2013

    • Author(s)
      Soeno Y, Fujita K, Kudo T, Asagiri M, Kakuta S, Taya Y, Shimazu Y, Sato K, Tanaka-Fujita R, Kubo S, Iwakura Y, Nakamura Y, Mori S, and Aoba T
    • Journal Title

      PLoS ONE

      Volume: 8 Issue: 8 Pages: e72105-e72105

    • DOI

      10.1371/journal.pone.0072105

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592716, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-24500488, KAKENHI-PROJECT-24592780, KAKENHI-PROJECT-24659822, KAKENHI-PROJECT-24689056, KAKENHI-PROJECT-25462935, KAKENHI-PROJECT-25463154
  • [Journal Article] Cathepsin K-dependent toll-like receptor 9 signaling revealed in experimental arthritis2008

    • Author(s)
      Asagiri, M., Hirai, T., Kunigami, T., Kamano, S., Gober, HJ., Okamoto, K., Nishikawa, K., Latz, E., Golenbock, D.T., Aoki, K., Ohya, K., Imai, Y., Morishita, Y., Miyazono, K., Kato, S., Saftig, P., Takayanagi, H.
    • Journal Title

      Science 319

      Pages: 624-627

    • Data Source
      KAKENHI-PROJECT-17GS0313
  • [Journal Article] Cathepsin K-dependent toll-like receptor 9 signaling revealed in experimental arthritis2008

    • Author(s)
      Asagiri, M.
    • Journal Title

      Science 319

      Pages: 624-627

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17GS0313
  • [Journal Article] Cathepsin K-dependent toll-like receptor 9 signaling revealed in experimental arthritis.2008

    • Author(s)
      Asagiri, M., et al.
    • Journal Title

      Science 319

      Pages: 624-627

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659099
  • [Journal Article] Toll-like Receptor 9 Signaling Revealed in Experimental Arthritis.2008

    • Author(s)
      Asagiri, M., et. al.
    • Journal Title

      Science 319

      Pages: 624-627

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17GS0313
  • [Journal Article] Cathepsin K-dependent Toll-like receptor 9 signaling revealed in experimental arthritis2008

    • Author(s)
      Asagiri M, Hirai T, Kunigami T, Kamano S, Gober HJ, Okamoto K, Nishikawa K, Latz E, Golenbock DT, Aoki K, Ohya K, Imai Y, Morishita Y, Miyazono K, Kato S, Saftig P, Takayanagi H.
    • Journal Title

      SCIENCE Volume: 319 Issue: 5863

      Pages: 624-627

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390410
  • [Journal Article] Cathepsin K-Dependent Toll-like Receptor 9 Signaling Revealed in Experimental Arthritis2008

    • Author(s)
      Asagiri, M., Hirai, T., Kunigami, T., Kamano, S., Gober, HJ., Okamoto, K., Nishikawa, K., Latz, E., Golenbock, DT., Aoki, K., Ohya, K., Imai, Y., Morishita, Y., Miyazono, K., Kato, S., Saftig, P., Takayanagi, H.
    • Journal Title

      Science 319

      Pages: 624-627

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659099
  • [Journal Article] Cathepsin K-Dependent Toll-like Receptor 9Signaling Revealed in Experimental Arthritis.2008

    • Author(s)
      Asagiri M, Hirai T, Kunigami T, Kamano S, Gober HJ, Okamoto K, Nishikawa K, Latz E, Golenbock DT, Aoki K, Ohya K, Imai Y, Morishita Y, Miyazono K, Kato S, Saftig P, Takayanagi H.
    • Journal Title

      SCIENCE 319

      Pages: 624-627

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390410
  • [Journal Article] Strategies for the treatment of rheumatoid arthritis and discovery of new drugs that target osteoclasts2007

    • Author(s)
      Kamano S, Asagiri M.
    • Journal Title

      PHARMSTAGE. 6

      Pages: 38-49

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390410
  • [Journal Article] NFAT機能の骨免疫学的考察2007

    • Author(s)
      朝霧成挙, 高柳広
    • Journal Title

      骨・関節・靱帯 20

      Pages: 781-788

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390410
  • [Journal Article] 関節リウマチ薬物治療の現状と破骨細胞をターゲットとした新薬像2007

    • Author(s)
      鎌野俊哉, 朝霧成挙
    • Journal Title

      PHARMSTAGE 6

      Pages: 38-49

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390410
  • [Journal Article] The molecular understanding of osteoclast differentiation.2007

    • Author(s)
      Asagiri, M, Takayanagi, H.
    • Journal Title

      Bone 40

      Pages: 251-264

    • Data Source
      KAKENHI-PROJECT-17GS0313
  • [Journal Article] The molecular understanding of osteoclast differentiation2007

    • Author(s)
      Asagiri M, Takayanagi H.
    • Journal Title

      BONE Volume: 40 Issue: 2

      Pages: 251-264

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390410
  • [Journal Article] NFAT機能の骨免疫学的考察2007

    • Author(s)
      朝霧成挙, 高柳広
    • Journal Title

      骨・関節・靱帯 20

      Pages: 781-788

    • Data Source
      KAKENHI-PROJECT-19659099
  • [Journal Article] The molecular understanding of osteoclast differentiation.2007

    • Author(s)
      Asagiri M, Takayanagi H.
    • Journal Title

      BONE 40

      Pages: 251-264

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390410
  • [Journal Article] 破骨細胞分化の転写制御2006

    • Author(s)
      朝霧成挙, 高柳広
    • Journal Title

      炎症と免疫 14

      Pages: 620-631

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390410
  • [Journal Article] 骨免疫学の最前線-転写因子NFATclによる骨代謝制御2006

    • Author(s)
      朝霧成挙, 高柳広
    • Journal Title

      医学のあゆみ 217

      Pages: 1119-1121

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390410
  • [Journal Article] A new frontier of osteoimmunology : regulation of bone homeostasis by NFAT family of transcription factors2006

    • Author(s)
      Asagiri M, Takayanagi H.
    • Journal Title

      Journal of Clinical and Experimental Medicine(Igaku no Ayumi) 217

      Pages: 1119-1121

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390410
  • [Journal Article] Transcriptional regulation of osteoclast-differentiation2006

    • Author(s)
      Asagiri M, Takayanagi H.
    • Journal Title

      Inflammation and Immunity(Ensho to Meneki) 5

      Pages: 620-631

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390410
  • [Journal Article] Autoamplification of NFATc1 expression determines its essential role in bone homeostasis.2005

    • Author(s)
      Asagiri Masataka
    • Journal Title

      Journal of Experimental Medicine 202(9)

      Pages: 1261-1269

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390434
  • [Journal Article] Autoamplification of NFATc1 determines its essential role in bone homeostasis.2005

    • Author(s)
      Asagiri, M. et al.
    • Journal Title

      J Exp Med 202・9

      Pages: 1261-1269

    • Data Source
      KAKENHI-PROJECT-16390434
  • [Journal Article] Autoamplification of NFATc1 determines its essential role in bone homeostasis.2005

    • Author(s)
      Asagiri, M. et al.
    • Journal Title

      J Exp Med 202・9

      Pages: 1261-1269

    • Data Source
      KAKENHI-PROJECT-17659298
  • [Journal Article] Contribution of NFATcl to the transcriptional control of immunoreceptor OSCAR but not TREM-2 during osteoclastogenesis.2005

    • Author(s)
      Kim, Y., Sato, K., Asagiri, M., Morita, I., Soma, K., Takayanagi, H.
    • Journal Title

      J Biol Chem 280・38

      Pages: 32905-32913

    • Data Source
      KAKENHI-PROJECT-17GS0313
  • [Journal Article] Autoamplification of NFATcl determines its essential role in bone homeostasis.2005

    • Author(s)
      Asagiri, M., Sato, K., Usami, T., Ochi, S., Nishina, H., Yoshida, H., Morita, I., Wagner, E.F., Mak, T.W., Serfling, E., Takayanagi, H.
    • Journal Title

      J Exp Med 202・9

      Pages: 1261-1269

    • Data Source
      KAKENHI-PROJECT-17GS0313
  • [Journal Article] NFAT and Osterix cooperatively regulate bone formation2005

    • Author(s)
      Koga, T., Matsui, Y., Asagiri, M., Kodama, T., de Crombrugghe, B., Nakashima K., Takayanagi, H.
    • Journal Title

      Nat Med 11

      Pages: 880-885

    • Data Source
      KAKENHI-PROJECT-17GS0313
  • [Journal Article] Contribution of nuclear factor of activated T cells c1 to the transcriptional control of immunoreceptor osteoclast-associated receptor but not triggering receptor expressed by myeloid cells-2 during osteoclastogenesis.2005

    • Author(s)
      Kim Y, Sato K, Asagiri M, Morita I, Soma K, Takayanagi H
    • Journal Title

      Journal of Biological Chemistry 280

      Pages: 32905-32913

    • Data Source
      KAKENHI-PROJECT-17659586
  • [Journal Article] Autoamplification of NFATc1 expression determines its essential role in bone homeostasis.2005

    • Author(s)
      Asagiri M, Sato K, Usami T, Ochi S, Nishina H, Yoshida H, Morita I, Wagner EF, Mak TW, Serfling E, Takayanagi H.
    • Journal Title

      Journal of Experimental Medicine 202

      Pages: 1261-1269

    • Data Source
      KAKENHI-PROJECT-17659586
  • [Journal Article] Inhibition of RANKL-induced Osteoclastogenesis by (-)-DHMEQ, a Novel NF-k B Inhibitor, through Downregulation of NFATcl.2005

    • Author(s)
      Takatsuna, H., Asagiri, M., Kubota, T., Oka, K., Osada, T., Sugiyama, C., Saito, H., Aoki, K., Ohya, K., Takayanagi, H., Umezawa, K.
    • Journal Title

      J Bone Mineral Res 20・4

      Pages: 653-662

    • Data Source
      KAKENHI-PROJECT-17GS0313
  • [Journal Article] NFAT and Osterix cooperatively regulate bone formation.2005

    • Author(s)
      Koga T, Matsui Y, Asagiri M, Kodama T, de Crombrugghe B, Nakashima K, Takayanagi H
    • Journal Title

      Nature Medicine 11

      Pages: 880-885

    • Data Source
      KAKENHI-PROJECT-17659586
  • [Journal Article] IRF-7 is the master regulator of type-1 interferon-dependent immune responses.2005

    • Author(s)
      Honda K, Yanai H, Negishi H, Asagiri M, Sato M, Mizutani T, Shimada N, Ohba Y, Takaoka A, Yoshida N, Taniguchi T
    • Journal Title

      Nature 434

      Pages: 772-777

    • Data Source
      KAKENHI-PROJECT-17659586
  • [Journal Article] Autoamplification of NFATc1 expression determines its essential role in bone homeostasis2005

    • Author(s)
      Asagiri Masataka
    • Journal Title

      Journal of Experimental Medicine 202(9)

      Pages: 1261-9

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390434
  • [Journal Article] Autoamplification of NFATc1 expression determines its essential role in bone homeostasis2005

    • Author(s)
      Asagiri, M., Sato, K., Usami, T., Ochi, S., Nishina, H., Yoshida, H., Morita, I., Wagner, E. F., Mak, T. W., Serfling, E., Takayanagi, H.
    • Journal Title

      J Exp Med 202

      Pages: 1261-1269

    • Data Source
      KAKENHI-PROJECT-17GS0313
  • [Journal Article] NFAT and Osterix cooperatively regulate bone formation.2005

    • Author(s)
      Koga, T., Matsui, Y., Asagiri, M., Kodama, T., Crombrugghe, B., Nakashima K., Takayanagi, H.
    • Journal Title

      Nat Med 11・8

      Pages: 880-885

    • Data Source
      KAKENHI-PROJECT-17GS0313
  • [Journal Article] Inhibition of RANKL-induced Osteoclastogenesis by (-)-DHMEQ, a Novel NF-κB Inhibitor. through Downregulation of NFATc1.

    • Author(s)
      Takatsuna, H., Asagiri, M., Kubota, T., Oka, K., 他7名
    • Journal Title

      J Bone Mineral Res (in press)

    • Data Source
      KAKENHI-PROJECT-16390434
  • [Journal Article] Inhibition of RANKL-induced Osteoclastogenesis by (-)-DHMEQ, a Novel NF-κB Inhibitor, through Downregulation of NFATc1.

    • Author(s)
      Takatsuna, H., Asagiri, M., Kubota, T., Oka, K., 他7名
    • Journal Title

      J Bone Mineral Res (in press)

    • Data Source
      KAKENHI-PROJECT-16659403
  • [Patent] カテプシン阻害剤を有効成分として含有するToll様受容体のシグナル伝達の調整剤2008

    • Inventor(s)
      高柳広、朝霧成挙、平井利武、
    • Industrial Property Rights Holder
      国立大学法人東京医科歯科大学、日本ケミファ株式会社
    • Filing Date
      2008-10-24
    • Data Source
      KAKENHI-PROJECT-19659099
  • [Patent] カテプシン阻害剤を有効成分として含有するTo11様受容体のシグナル伝達の調整剤2007

    • Inventor(s)
      高柳広, 朝霧成挙, 平井利武
    • Industrial Property Rights Holder
      国立大学法人 東京医科歯科大学, 日本ケミフア株式会
    • Filing Date
      2007
    • Data Source
      KAKENHI-PROJECT-19659099
  • [Patent] カテプシン阻害剤を有効成分として含有するTLRのシグナル伝達の調整剤2007

    • Inventor(s)
      高柳広, 朝霧成挙, 平井利武
    • Industrial Property Rights Holder
      東京医科歯科大学、日本ケミファ株式会社
    • Filing Date
      2007
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390410
  • [Patent] カテプシン阻害剤を有効成分として含有するToll様受容体のシグナル伝達の調整剤2007

    • Inventor(s)
      高柳広、朝霧成挙、平井利武
    • Industrial Property Rights Holder
      東京医科歯科大学、日本ケミファ株式会社
    • Filing Date
      2007-10-24
    • Data Source
      KAKENHI-PROJECT-17GS0313
  • [Presentation] Inhibitory effect of spermidine on differentiation of inflammatory osteoclasts2022

    • Author(s)
      Seiya Tanaka, Asuka Okamoto, Honoka Tsubaki, Tetsuya Seto, Hiroki Sakai, Takeshi Honda, Masataka Asagiri
    • Organizer
      第95回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-21K06803
  • [Presentation] Synthetic retinoid bexarotene inhibits differentiation of inflammatory osteoclasts.2022

    • Author(s)
      Hina Takegami, Hiyori Nakamura, Ayano Takeda, Mayu Matsuo, Hiroki Sakai, Takeshi Honda, Masataka Asagiri
    • Organizer
      第95回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-21K06803
  • [Presentation] カテプシンKはToll様受容体9シグナルを介して自己免疫性炎症疾患の重症度を決定する2008

    • Author(s)
      朝霧成挙, 他
    • Organizer
      第52回日本リウマチ学会総会・学術集会ワークショップ9「関節リウマチの病因・病態1」
    • Place of Presentation
      札幌
    • Year and Date
      2008-04-22
    • Data Source
      KAKENHI-PROJECT-17GS0313
  • [Presentation] 骨溶解酵素カテプシンKはTLR9信号を制御して 自己免疫性炎症疾患の重症度を決定する2008

    • Author(s)
      朝霧成挙
    • Organizer
      第2回 Bone Research Seminar
    • Place of Presentation
      丸ビル(東京)
    • Year and Date
      2008-02-29
    • Data Source
      KAKENHI-PROJECT-19659099
  • [Presentation] 第2回Bone Research Seminar2008

    • Author(s)
      朝霧成挙
    • Organizer
      骨溶解酵素カテプシンKはTLR9信号を制御して自己免疫性炎症疾患の重症度を決定する
    • Place of Presentation
      丸ビル(東京)
    • Year and Date
      2008-02-29
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390410
  • [Presentation] カテプシンKはToll様受容体9シグナルを介して自己免疫性炎症疾患の重症度を決定する2008

    • Author(s)
      朝霧成挙, 他
    • Organizer
      第52回目本リウマチ学会総会・学術集会ワークショップ9「関節リウマチの病因・病態1」
    • Place of Presentation
      札幌
    • Year and Date
      2008-04-22
    • Data Source
      KAKENHI-PROJECT-19659099
  • [Presentation] The POZ-Zn transcriptional regulator OCZF/LRF is induced by RANKL and increases c-Fos expression in osteoclastogenesis.2007

    • Author(s)
      Kukita A, Shobuike T, Asagiri M, Takayanaie H, Pessler F, Matsuo K, Kukita T
    • Organizer
      ASBMR 29th Annual Meeting
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Year and Date
      2007-09-19
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390410
  • [Presentation] Targeting Cathepsin K in autoimmune arthritis reveals its function in dendritic cells2007

    • Author(s)
      ASAGIRI Masataka, HIRAI Toshitake, KUNIGAMI Toshihiro, KAMANO Shunya, GOBER Hans-Juergen, OKAMOTO Kazuo, NISHIKAWA Keizo, MORISHITA Yasuyuki, TAKAYANAGI Hiroshi
    • Organizer
      第36回日本免疫学会総会・学術集会
    • Place of Presentation
      品川プリンスホテル(東京)
    • Year and Date
      2007-11-22
    • Data Source
      KAKENHI-PROJECT-19659099
  • [Presentation] The POZ-Zn transcriptional regulator OCZF/LRF is induced by RANKL and increases c-Fos expression in osteoclastogenesis2007

    • Author(s)
      Kukita A, Shobuike T, Asagiri M, Takayanagi H, Pessler F, Matsuo K, Kukita T
    • Organizer
      ASBMR 29th Annual Meeting
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Year and Date
      2007-09-19
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390410
  • [Presentation] Regulation of dendritic cell function by cathepsin K.2007

    • Author(s)
      朝霧成挙, 他
    • Organizer
      日本免疫学会総会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2007-11-22
    • Data Source
      KAKENHI-PROJECT-17GS0313
  • [Presentation] Targeting Cathepsin K in autoimune arthritis reveals its function in dendritic cells2007

    • Author(s)
      ASAGIRI Masataka, HIRAI Toshitake, KUNIGAMI Toshihiro, KAMANO Shunya, GOBER Hans-Juergen, OKAMOTO Kazuo, NISHIKAWA Keizo, MORISHITA Yasuyuki, TAKAYANAGI Hiroshi
    • Organizer
      第37回日本免疫学会総会・学術集会
    • Place of Presentation
      品川プリンスホテル(東京)
    • Year and Date
      2007-11-22
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390410
  • [Presentation] Expression of OCZF directed by the cathepsin K promoter affects bone mass and osteoclast formation in transgenic mice.2007

    • Author(s)
      Shobuike T, Kukita T, Nagata K, Teramachi J, Asagiri M, Takayanagi H, Kukita A
    • Organizer
      ASBMR 29th Annual Meeting
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Year and Date
      2007-09-19
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390410
  • [Presentation] Targeting Cathepsin K in autoimmune arthritis reveals its function in dendritic cells2007

    • Author(s)
      ASAGIRI Masataka, HIRAI Toshitake, KUNIGAMI Toshihiro, KAMANO Shunya, GOBER Hans-Juergen, OKAMOTO Kazuo, NISHIKAWA Keizo, MORISHITA Yasuyuki, TAKAYANAGI Hiroshi
    • Organizer
      Japan Society for Immunology 37^<th> Annual Meeting
    • Place of Presentation
      Tokyo, Japan
    • Year and Date
      2007-11-22
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390410
  • [Presentation] Expression of OCZF directed by the cathepsin K promoter affects bone mass and osteoclast formation in transgenic mice2007

    • Author(s)
      Shobuike T, Kukita T, Nagata K, Teramachi J, Asagiri M, Takayanagi H, Kukita A
    • Organizer
      ASBMR 29th Annual Meeting
    • Place of Presentation
      Honolulu, Hawaii, USA
    • Year and Date
      2007-09-19
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390410
  • [Presentation] Selective Inhibition of Cathepsin Kameliorates bone destruction and inflammation in autoimmune arthritis2006

    • Author(s)
      ASAGIRI Masataka, KAMANO Shunya, KUNIGAMI Toshihiro, NISHIKAWA Keizo, MATSUURA Masao, TAKAYANAGI Hiroshi
    • Organizer
      第36回日本免疫学会総会・学術集会
    • Place of Presentation
      大阪国際会議場、大阪
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390410
  • [Presentation] カルシウムシグナル/NFATclによる運命決定2006

    • Author(s)
      佐藤浩二郎、朝霧成挙、古賀貴子、高柳広
    • Organizer
      第24回日本骨代謝学会学術集会
    • Place of Presentation
      東京ファッションタウン、東京
    • Year and Date
      2006-07-06
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390410
  • [Presentation] NFATファミリー転写因子を標的とした骨破壊制御2006

    • Author(s)
      古賀貴子、松井郁一、朝霧成挙、中島和久、高柳広
    • Organizer
      第50回日本リウマチ学会学術集会
    • Place of Presentation
      長崎
    • Year and Date
      2006-04-25
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390410
  • [Presentation] Selective Inhibition of Cathepsin K ameliorates bone destruction and inflammation in autoimmune arthritis2006

    • Author(s)
      ASAGIRI Masataka, KAMANO Shunya, KUNIGAMI Toshihiro, NISHIKAWA Keizo, MATSUURA Masao, TAKAYANAGI Hiroshi
    • Organizer
      Japan Society for Immunology 36^<th> Annual Meeting
    • Place of Presentation
      Osaka, Japan
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390410
  • [Presentation] NFATc1の自己制御による発現増強は骨格系の恒常性維持に必須の役割を果たす2006

    • Author(s)
      朝霧成挙、佐藤浩二郎、越智小枝、鎌野俊哉、高柳広
    • Organizer
      第50回日本リウマチ学会学術集会
    • Place of Presentation
      長崎
    • Year and Date
      2006-04-25
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390410
  • [Presentation] Involvement of regulated necrosis in the pathogenesis of drug-induced acute liver failure

    • Author(s)
      Takemoto K, Hatano E, Iwaisako K, Toriguchi K, Tanabe K, Taura K, Uemoto S, Asagiri M.
    • Organizer
      SOT 2015 (54th Annual Meeting and ToxExpo of the Society of Toxicology)
    • Place of Presentation
      San Diego Convention Center (San Diego, California, USA)
    • Year and Date
      2015-03-22 – 2015-03-26
    • Data Source
      KAKENHI-PROJECT-24689056
  • [Presentation] 薬剤性劇症肝炎の病態形成における制御性壊死の関与

    • Author(s)
      竹本研史, 波多野悦朗, 祝迫惠子, 竹入雅敏, 野間成人, 鳥口寛, 田邉和孝, 瀬尾智, 田浦康二朗, 朝霧成挙, 上本伸二
    • Organizer
      第35回日本炎症・再生医学会
    • Place of Presentation
      万国津梁館 (沖縄)
    • Year and Date
      2014-07-01 – 2014-07-04
    • Data Source
      KAKENHI-PROJECT-24659822
  • [Presentation] 薬剤性劇症肝炎の病態形成における制御性壊死の関与

    • Author(s)
      竹本研史,波多野悦朗,祝迫惠子,竹入雅敏,野間成人,鳥口寛,田邉和孝,瀬尾智,田浦康二朗,朝霧成挙,上本伸二
    • Organizer
      第35回日本炎症・再生医学会
    • Place of Presentation
      万国津梁館 (沖縄)
    • Year and Date
      2014-07-01 – 2014-07-04
    • Data Source
      KAKENHI-PROJECT-24689056
  • [Presentation] Involvement of regulated necrosis in the pathogenesis of drug-induced acute liver failure

    • Author(s)
      Takemoto K, Hatano E, Iwaisako K, Toriguchi K, Tanabe K, Taura K, Uemoto S, Asagiri M.
    • Organizer
      SOT 2015 (54th Annual Meeting and ToxExpo of the Society of Toxicology)
    • Place of Presentation
      San Diego Convention Center (San Diego, California, USA)
    • Year and Date
      2015-03-22 – 2015-03-26
    • Data Source
      KAKENHI-PROJECT-24659822
  • 1.  TAKAYANAGI Hiroshi (20334229)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 33 results
  • 2.  SATO Kojiro (10372434)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 8 results
  • 3.  SHINOHARA Masahiro (60345733)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  NAKASHIMA Tomoki (00346959)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 5.  SATOH Hitoshi (70183829)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  柳井 亮二 (10346554)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  油形 公則 (40564430)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  辻 竣也 (80898370)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  ENDO Hideya (40037320)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  Honda Takeshi (30457311)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 11.  春宮 覚 (50301792)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  古賀 貴子 (90451905)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 13.  森 茂郎 (30010424)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  酒井 大樹 (40464367)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 15.  内 翔平 (20939277)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  朝霧 成拳
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  飯田 隆
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 18.  佐藤 かおり
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 19.  青葉 孝昭
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  島津 徳人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 21.  添野 雄一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 22.  田谷 雄二
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

URL: 

Are you sure that you want to link your ORCID iD to your KAKEN Researcher profile?
* This action can be performed only by the researcher himself/herself who is listed on the KAKEN Researcher’s page. Are you sure that this KAKEN Researcher’s page is your page?

この研究者とORCID iDの連携を行いますか?
※ この処理は、研究者本人だけが実行できます。

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi