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Hashiguchi Masaaki  橋口 昌章

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… Alternative Names

橋口 昌章  ハシグチ マサアキ

HASHIGUCHI Masaaki  橋口 昌章

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Researcher Number 20372443
Other IDs
External Links
Affiliation (Current) 2025: 東京大学, 大学院農学生命科学研究科(農学部), 特任研究員
Affiliation (based on the past Project Information) *help 2025: 日本医科大学, 先端医学研究所, 准教授
2022 – 2023: 日本医科大学, 先端医学研究所, 准教授
2012 – 2020: 獨協医科大学, 医学部, 准教授
2011: 獨協医科大学, 医学部, 免疫学講座
2010 – 2011: 獨協医科大学, 医学部, 助教 … More
2010: 東京医科歯科大学, 大学院・医歯学総合研究科, 助教
2009: Tokyo Medical and Dental University, 医歯学総合研究科, 助教
2007 – 2008: Tokyo Medical and Dental University, 大学院・医歯学総合研究科, 助教
2006: 東京医科歯科大学, 大学院医歯学総合研究科, 助手
2004 – 2005: 東京医科歯科大学, 大学院・医歯学総合研究科, 助手 Less
Review Section/Research Field
Principal Investigator
Basic Section 38050:Food sciences-related / Pathobiological dentistry/Dental radiology / Food science
Except Principal Investigator
Pathobiological dentistry/Dental radiology / Biological Sciences / 病態科学系歯学(含放射線系歯学) / 膠原病・アレルギー・感染症内科学
Keywords
Principal Investigator
IgA / IL-21 / パイエル板 / アレルギー / 補助シグナル / 炎症 / 感染 / 免疫 / Tfh / 形質細胞 … More / IgG1 / IgE / BAFF / APRIL / IL-22 / 腸内細菌 / 自然リンパ球 / mucosal immunity / co-signal molecule / keratinocyte / 補助刺激分子 / 粘膜免疫 / 補助シグナル分子 / 角化上皮細胞 / マーキング / GFP / 好酸球 / IL-33 / IL-5 / Tlt2 / 抗腫瘍免疫 / TLT2 / B7-H3 / ヒト免疫応答 / 破骨細胞 / T細胞 … More
Except Principal Investigator
免疫 / T細胞 / 樹状細胞 / 免疫制御 / 補助シグナル分子 / 歯学 / 歯髄 / RNA干渉 / 炎症 / 口腔粘膜 / 自己免疫 / 免疫学 / 制御性T細胞 / T lymphocytes / Dendritic cells / Oral diseases / Costimulatory molecules / Cancer / Infectious diseases / Dentistry / Immunology / 細胞間相互作用 / 破骨細胞 / 補助シグナル / 骨吸収 / 歯髄炎 / 粘膜上皮細胞 / 口腔粘膜疾患 / 口腔疾患 / 癌 / 感染症 / HIF-1α / B細胞分化 / 解糖系 / HIF-1a / 歯周疾患 / イメージング / 免疫療法 / 感染 / 細胞療法 / 免疫回避機構 / がん免疫 / CD86 / 接触性過敏症 / RNAi / 抑制シグナル分子 / B7 / 免疫細胞 / 抑制分子 / 免疫応答 / 免疫寛容 / ホメオスターシス / B7ファミリー Less
  • Research Projects

    (16 results)
  • Research Products

    (87 results)
  • Co-Researchers

    (11 People)
  •  パイエル板自然リンパ球およびB細胞による腸内細菌制御Principal Investigator

    • Principal Investigator
      橋口 昌章
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 38050:Food sciences-related
    • Research Institution
      Nippon Medical School
  •  パイエル板Tfhによる抗体産生制御:対立遺伝子排除の破綻とアレルギーの抑制Principal Investigator

    • Principal Investigator
      橋口 昌章
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 38050:Food sciences-related
    • Research Institution
      Nippon Medical School
  •  Does IL-21 produced in Peyer's patch regulate the affinity of IgA and food allergy?Principal Investigator

    • Principal Investigator
      Hashiguchi Masaaki
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 38050:Food sciences-related
    • Research Institution
      Dokkyo Medical University
  •  Peyer's patch immune cells regulates intestinal bacteria: basic research for the manipulation of intestinal bacteria by foodsPrincipal Investigator

    • Principal Investigator
      HASHIGUCHI Masaaki
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Food science
    • Research Institution
      Dokkyo Medical University
  •  Functional study of IL-5-producing cells in food allergy using GFP marking systemPrincipal Investigator

    • Principal Investigator
      MASAAKI Hashiguchi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Food science
    • Research Institution
      Dokkyo Medical University
  •  Regulatory roles of HIF-1a and glycolysis in autoimmunity

    • Principal Investigator
      KOBATA Tetsuji
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Dokkyo Medical University
  •  T細胞に依存しない新たな補助シグナル分子機能の解明

    • Principal Investigator
      東 みゆき
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Medical and Dental University
  •  Immune regulation of oral disease by co-signal molecule B7-H3 and the novel receptor.Principal Investigator

    • Principal Investigator
      HASHIGUCHI Masaaki
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Dokkyo Medical University
      Tokyo Medical and Dental University
  •  Analyses of Regulatory Mechanisms in Oral Immune Responses and Development of a New Immunotherapy Targeting Dendritic Cells

    • Principal Investigator
      AZUMA Miyuki
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Tokyo Medical and Dental University
  •  機能T細胞のマルチイメージング化による歯周疾患の免疫病態解析手法の確立

    • Principal Investigator
      東 みゆき
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Tokyo Medical and Dental University
  •  Triggering receptor expressed on myeloid cell-like transcript 2(TLT-2)is a counter-receptor for B7-H3 and enhances T cell responsesPrincipal Investigator

    • Principal Investigator
      HASHIGUCHI Masaaki
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Tokyo Medical and Dental University
  •  周囲環境により変化する多機能性ミエロイド細胞の癌治療への応用

    • Principal Investigator
      東 みゆき
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Medical and Dental University
  •  RNA干渉による口腔粘膜の炎症制御に関する研究

    • Principal Investigator
      東 みゆき
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Tokyo Medical and Dental University
  •  The Regulation of Oral Mucosa Immunity by Immune Co-inhibitory MoleculesPrincipal Investigator

    • Principal Investigator
      HASHIGUCHI Masaaki
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Tokyo Medical and Dental University
  •  ホメオスターシスと自己寛容に関わるT細胞補助刺激分子の機能解析とその人為的制御

    • Principal Investigator
      AZUMA Miyuki
    • Project Period (FY)
      2001 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Medical and Dental University
  •  Functional analysis of costimulatory molecules in oral diseases and their intervention for clinical application

    • Principal Investigator
      AZUMA Miyuki
    • Project Period (FY)
      2001 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      病態科学系歯学(含放射線系歯学)
    • Research Institution
      Tokyo Medical and Dental University

All 2024 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2004 Other

All Journal Article Presentation

  • [Journal Article] IL-21 and IL-5 coordinately induce surface IgA+ cells2020

    • Author(s)
      Hashiguchi Masaaki、Kashiwakura Yuji、Kanno Yumiko、Kojima Hidefumi、Kobata Tetsuji
    • Journal Title

      Immunology Letters

      Volume: 224 Pages: 21-27

    • DOI

      10.1016/j.imlet.2020.05.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K05478
  • [Journal Article] Peyer’s patches contain abundant isotype-switched B cells with activated phenotypes and are inductive sites for T-independent anti-DNA IgA2019

    • Author(s)
      Hashiguchi, M., Kashiwakura, Y., Kojima, H., Kanno, Y., Kobata, T.
    • Journal Title

      Immunol. Lett.

      Volume: 211 Pages: 53-59

    • DOI

      10.1016/j.imlet.2019.05.015

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K05478
  • [Journal Article] Tumor necrosis factor superfamily member (TNFSF) 13 (APRIL) and TNFSF13B (BAFF) downregulate homeostatic immunoglobulin production in the intestines2018

    • Author(s)
      Hashiguchi, M., Kashiwakura, Y., Kanno, Y., Kojima, H., Kobata, T.
    • Journal Title

      Cell. Immunol.

      Volume: 323 Pages: 41-48

    • DOI

      10.1016/j.cellimm.2017.10.009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K07438
  • [Journal Article] IL-33 activates eosinophils of visceral adipose tissue both directly and via innate lymphoid cells2015

    • Author(s)
      Hashiguchi, M., Kashiwakura, Y., Kojima, H., Kobayashi, A., Kanno, Y., Kobata, T.
    • Journal Title

      Eur. J. Immunol.

      Volume: 45 Issue: 3 Pages: 876-885

    • DOI

      10.1002/eji.201444969

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24580196
  • [Journal Article] CD2-mediated regulation of peripheral CD4+CD25+ regulatory T cell apoptosis accompanied with down regulation of Bim2013

    • Author(s)
      Kashiwakura Y, Sakurai D, Kanno Y, Hashiguchi M, Kobayashi A, Kurosu A, Tokudome S, Kobata T, Kojima H.
    • Journal Title

      Immunology

      Volume: 139 Issue: 1 Pages: 48-60

    • DOI

      10.1111/imm.12054

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591454
  • [Journal Article] Antibodies against B7-DC with differential binding properties exert opposite effects2012

    • Author(s)
      Ritprajak P, Hashiguchi M, Akiba H, Yagita H, Okumura K, Azuma M
    • Journal Title

      Hybridoma

      Volume: 31 Issue: 1 Pages: 40-47

    • DOI

      10.1089/hyb.2011.0087

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-22021016, KAKENHI-PROJECT-22591098, KAKENHI-PROJECT-23249082, KAKENHI-PROJECT-23390260
  • [Journal Article] Human B7-H3 binds to Triggering receptor expressed on myeloid cell-like transcript 2(TLT-2) and enhances T cell responses. Open J2012

    • Author(s)
      M. Hashiguchi, Y. Inamochi, S. Nagai, S., N. Otsuki, P. Jinhua, H. Kobori, Y. Kanno, T. Kobata, M. Azuma
    • Journal Title

      Immunol. Peer-reviewed

      Volume: 2 Issue: 01 Pages: 9-16

    • DOI

      10.4236/oji.2012.21002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592385, KAKENHI-PUBLICLY-22021016, KAKENHI-PROJECT-23249082
  • [Journal Article] B7-H1 overexpression regulates epithelial-mesenchymal transition and accelerates carcinogenesis in skin.2011

    • Author(s)
      Cao Y, Zhang L, Kamimura Y, Ritprajak P, Hashiguchi M, Hirose S, Azuma M
    • Journal Title

      Cancer Res. 71(4)

      Pages: 1235-1243

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249075
  • [Journal Article] B7-H1 overexpression regulates epithelial-mesenchymal transition and accelerates carcinogenesis in skin2011

    • Author(s)
      Cao Y, Zhang L, Kamimura Y, Ritprajak P, Hashiguchi M, Hirose S, Azuma M
    • Journal Title

      Cancer Res

      Volume: 71 Issue: 4 Pages: 1235-43

    • DOI

      10.1158/0008-5472.can-10-2217

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-22021016, KAKENHI-PROJECT-22791809, KAKENHI-PROJECT-23249082
  • [Journal Article] Immunoregulatory molecules B7-H1 (CD274) contributes to skin carcinogenesis2011

    • Author(s)
      Cao Y, Zhang L, Ritprajak P, Tsushima F, Youngnak-Piboonratanakit P, Kamimura Y, Hashiguchi M, Azuma M
    • Journal Title

      Cancer Res

      Volume: 71 Issue: 14 Pages: 4737-4741

    • DOI

      10.1158/0008-5472.can-11-0527

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-22021016, KAKENHI-PROJECT-22791809, KAKENHI-PROJECT-23249082
  • [Journal Article] Topical application of siRNA targeting cutaneous dendritic cells in allergic skin disease.2010

    • Author(s)
      Azuma M, Ritprajak P, Hashiguchi M
    • Journal Title

      Methods Mol Biol 623

      Pages: 373-81

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249075
  • [Journal Article] Enhancement of effector CD8+ T cell function by tumour-associated B7-H3 and modulation of its counter receptor triggering receptor expressed on myeloid cell-like transcripts 2 (TLT-2) at tumor sites.2010

    • Author(s)
      Kobori H, Hashiguchi M, Piao J, Kato M, Ritprajak P, Azuma M
    • Journal Title

      Immunology 130(3)

      Pages: 363-373

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249075
  • [Journal Article] Keratinocytes-associetd B7-H1 directly regulated cutaneous effector CD8+ T cell responses2010

    • Author(s)
      Ritprajak P, Hashiguchi M, Azuma M, et al.
    • Journal Title

      J.Immunol (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249075
  • [Journal Article] Enhancement of effector CD8^+T cell function by tumor-associated B7-H3 and modulation of its counter receptor triggering receptor expressed on myeloid cell-like transcript 2(TLT-2) at tumor sites2010

    • Author(s)
      H. Kobori, M. Hashiguchi, J. Piao, M. Kato, P. Ritprajak, M. Azuma
    • Journal Title

      Immunology Peer-reviewed

      Volume: 130 Issue: 3 Pages: 363-373

    • DOI

      10.1111/j.1365-2567.2009.03236.x

    • Data Source
      KAKENHI-PROJECT-21592385
  • [Journal Article] Enhancement of effector CD8^+ T cell function by tumor-associated B7-H3 and modulation of its counter receptor triggering receptor expressed on myeloid cell-like transcript 2 (TLT-2) at tumor sites2010

    • Author(s)
      H.Kobori, M.Hashiguchi, J.Piao, M.Kato, P.Ritprajak, M.Azuma
    • Journal Title

      Immunology 130

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592385
  • [Journal Article] Keratinocytes-associated B7-H1 directly regulates cutaneous effector CD8+ T cell responses.2010

    • Author(s)
      itprajak P, Hashiguchi M, Tsushima F, Chalermsarp N, Azuma M
    • Journal Title

      J.Immunol. 184

      Pages: 4818-4925

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249075
  • [Journal Article] Possible involvement of soluble B7-H4 in T-cell-mediated inflammatory immune responses.2009

    • Author(s)
      Kamimura Y, kobori H, Piao J, Hashiguchi M, Matsumoto K, Horose S, Azuma M
    • Journal Title

      Biochem Biophys Res Commun 389

      Pages: 349-353

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249075
  • [Journal Article] Enhancement of T cell-mediated anti-tumor immunity via the ectopically expressed glucocruticoid-induced tumor necrosis factor receptor-related receptor ligand on tumors.2009

    • Author(s)
      Piao J, Kamimura Y, Iwai H, Cao Y, Kikuchi K, Hashiguchi M, Masunaga T, Jiang H, Tamura K, Sakaguchi S. Azuma M
    • Journal Title

      Immunology 127

      Pages: 489-499

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249075
  • [Journal Article] The Glucocorticoid-induced TNFR-related protein (GITR)-GITR ligand pathway acts as a mediator of cutaneous dendritic cell migration and promotes T-cell mediated acquired immunity.2009

    • Author(s)
      Kamimura Y, Iwai H, Piao J, Hashiguchi M, Azuma M
    • Journal Title

      J Immunol 182

      Pages: 2708-2716

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249075
  • [Journal Article] GITR ligand-costimulation activates effector and regulatory functions of CD4+ T cells.2008

    • Author(s)
      Igarashi H, Cao Y, Iwai H, Piao J, Kamimura Y, Hashiguchi M, Amagasa T. Azuma M
    • Journal Title

      Biochem Biophys Res Commun 369

      Pages: 1134-1138

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249075
  • [Journal Article] Topical application of cream-emulsified CD86 siRNA ameliorates allerg ic skin disease by targeting cutaneous dendritic cells.2008

    • Author(s)
      Ritprajak P, Hashiguchi M, Azuma M
    • Journal Title

      Mol Ther 16(7)

      Pages: 1323-1330

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249075
  • [Journal Article] Triggering receptor expressed on myeloid cell-like transcript 2 (TLT-2) is a counter-receptor for B7-H3 and enhances T cell responses2008

    • Author(s)
      Hashiguchi, M., Kobori, H., Ritprajak, P., Kamimura, Y., Kozono, H., Azuma, M.
    • Journal Title

      Proc.Natl.Acad.Sci.USA 105

      Pages: 10495-10500

    • Data Source
      KAKENHI-PROJECT-19592168
  • [Journal Article] Trigerring receptor expressed on myeloid cell-like transcript 2 (TLT-2) is a counter-receptor for B7-H3 and enhances T cell responses.2008

    • Author(s)
      Hashiguchi M, Kobori H, Ritprajak P, Kamimura Y, Kozono H, Azuma M
    • Journal Title

      Proc.Nathl.Acad.Sci.USA 105

      Pages: 10495-10500

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249075
  • [Journal Article] Trigerring receptor expressed on myeloid cell-like transcript 2 (TLT-2) is a counter-receptor for B7-H3 and enhances T cell responses2008

    • Author(s)
      Hashiguchi M, Azuma M, Kobori H, et al.
    • Journal Title

      Proc. Nathl. Acad. Sci. USA 105

      Pages: 10495-500

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249075
  • [Journal Article] Triggering receptor expressed on myeloid cell-like transcript 2 (TLT-2)is acounter-receptor for B7-H3 and enhances T cell responses2008

    • Author(s)
      Hashiguchi, M., Kobori, H., Ritprajak, P., Kamimura, Y., Kozono, H., Azuma, M.
    • Journal Title

      Proc. Natl. Acad. Sci. USA 105

      Pages: 10495-10500

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592168
  • [Journal Article] B7ファミリーと免疫応答の制御2004

    • Author(s)
      橋口昌章, 東みゆき
    • Journal Title

      臨床免疫 42

      Pages: 85-89

    • NAID

      40006351220

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16591884
  • [Journal Article] Mini-review; Immunoregulatory molecules B7-H1 (CD274) contributes to skin carcinogenesis.

    • Author(s)
      Cao Y, Zhang L, Ritprajak P, Tsushima F, Youngnak-Piboonratanakit P, Kamimura Y, Hashiguchi M, Azuma M
    • Journal Title

      Cancer Res. in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249075
  • [Presentation] Interleukin 21 commits IgG1+ cells not to undergo class switch to IgE but to differentiate into plasmablasts2024

    • Author(s)
      Masaaki Hashiguchi, Yoshiko Iwai
    • Organizer
      第52回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-22K05481
  • [Presentation] RORalpha is crucial for the survival of IgA+ plasma cells but not B220+ IgA+ cells2019

    • Author(s)
      Hashiguchi, M., Kashiwakura, Y., Kanno, Y., Kojima, H., Kobata, T.
    • Organizer
      第48回日本免疫学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-18K05478
  • [Presentation] IL-21 and CD4+ T cells are required for Peyer’s patch germinal center formation but not for intestinal IgA in homeostatic condition2018

    • Author(s)
      Hashiguchi, M., Kashiwakura, Y., Kanno, Y., Kojima, H., Kobata, T.
    • Organizer
      第47回日本免疫学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-18K05478
  • [Presentation] Tumor necrosis factor superfamily member (TNFSF) 13, APRIL and TNFSF13B, BAFF downregulate homeostatic immunoglobulin production in intestines2017

    • Author(s)
      Hashiguchi, M., Kashiwakura, Y., Kojima, H., Kanno, Y., Kobata, T.
    • Organizer
      第46回日本免疫学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-15K07438
  • [Presentation] Differences in specificity and production between IgA and IgG in Peyer’s patches2016

    • Author(s)
      Masaaki Hashiguchi, Yuji Kashiwakura, Hidefumi Kojima, Yumiko Kanno, Tetsuji Kobata
    • Organizer
      日本免疫学会学術集会
    • Place of Presentation
      沖縄コンベンションセンター (沖縄県 宜野湾市)
    • Year and Date
      2016-12-05
    • Data Source
      KAKENHI-PROJECT-15K07438
  • [Presentation] Peyer’s patch innate lymphoid cells regulate commensal bacteria expansion2016

    • Author(s)
      Masaaki Hashiguchi, Ayano Kobayashi, Yuji Kashiwakura, Hidefumi Kojima, Yumiko Kanno, Tetsuji Kobata
    • Organizer
      International Congress of Immunology 2016
    • Place of Presentation
      Melbourne, Australia
    • Year and Date
      2016-08-22
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K07438
  • [Presentation] Peyer’s patch innate lymphoid cells regulate commensal bacteria expansion2015

    • Author(s)
      Hashiguchi Masaaki, Kashiwakura Yuji, Kojima Hidefumi, Kanno Yumiko, Kobata Tetsuji
    • Organizer
      日本免疫学会学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2015-11-20
    • Data Source
      KAKENHI-PROJECT-15K07438
  • [Presentation] Cellular metabolism of CD4+ CD25+ regulatory T cells is distinct from that of CD4+ CD25- conventional T cells2014

    • Author(s)
      Kojima H, Kanno Y, Kashiwakura Y, Hashiguchi M, Kobata T
    • Organizer
      第43回日本免疫学会学術集会
    • Place of Presentation
      京都
    • Year and Date
      2014-12-12
    • Data Source
      KAKENHI-PROJECT-24591454
  • [Presentation] Glycolysis, that impacts on bone marrow B cell development, dose not have a decisive influence on peripheral B cell differentiation2014

    • Author(s)
      Kanno Y, Kashiwakura T, Hashiguchi M, Kobata T, Kojima H
    • Organizer
      第43回日本免疫学会学術集会
    • Place of Presentation
      京都
    • Year and Date
      2014-12-11
    • Data Source
      KAKENHI-PROJECT-24591454
  • [Presentation] Dual activation pathways of visceral adipose tissue eosinophils by interleukin-33 in vivo: innate lymphoid cell-mediated and direct actions2014

    • Author(s)
      Hashiguchi Masaaki, Kashiwakura Yuji, Kojima Hidefumi, Kanno Yumiko, Kobata Tetsuji
    • Organizer
      日本免疫学会学術集会
    • Place of Presentation
      京都
    • Year and Date
      2014-12-11
    • Data Source
      KAKENHI-PROJECT-24580196
  • [Presentation] CD2 stimulation upregulates Foxp3 in murine peripheral regulatory T cells2014

    • Author(s)
      Kashiwakura Y, Kanno Y, Hashiguchi M, Kobata T, Kojima H
    • Organizer
      第43回日本免疫学会学術集会
    • Place of Presentation
      京都
    • Year and Date
      2014-12-12
    • Data Source
      KAKENHI-PROJECT-24591454
  • [Presentation] TCR-independent CD4+CD25+ regulatory T cell activation during immune responses2013

    • Author(s)
      Kojima H, Kashiwakura Y, Hashiguchi M, Kobata T.
    • Organizer
      15th international Congress of Immunology
    • Place of Presentation
      Milan, Italy
    • Data Source
      KAKENHI-PROJECT-24591454
  • [Presentation] CD2-mediated regulation of peripheral CD4+CD25+ regulatory T cell apoptosis accompanied by downregulation of Bim2013

    • Author(s)
      Kashiwakura Y, Sakurai D, Kanno Y, Hashiguchi M, Kobayashi A, Kurosu A, Tokudome S, Kobata T, Kojima H.
    • Organizer
      15th international Congress of Immunology
    • Place of Presentation
      Milan, Italy
    • Data Source
      KAKENHI-PROJECT-24591454
  • [Presentation] HIF-1α is regulated by IL-7 in pro-B cells during B cell development.2013

    • Author(s)
      Kanno Y, Kashiwakura T, Hashiguchi M, Kobata T, Kojima H.
    • Organizer
      第42回日本免疫学会学術集会
    • Place of Presentation
      千葉市
    • Data Source
      KAKENHI-PROJECT-24591454
  • [Presentation] Cytokine-dependent CD4+CD25+ regulatory T cell activation during immune responses2013

    • Author(s)
      Kojima H, Kanno Y, Kashiwakura Y, Hashiguchi M, Kobata T.
    • Organizer
      第42回日本免疫学会学術集会
    • Place of Presentation
      千葉市
    • Data Source
      KAKENHI-PROJECT-24591454
  • [Presentation] CD2-mediated regulation of peripheral CD4+CD25+ regulatory T cell apoptosis accompanied by down regulation of Bim2013

    • Author(s)
      Kashiwakura Y, Sakurai D., Kanno Y, Hashiguchi M, Kobata T, Kojima H.
    • Organizer
      第42回日本免疫学会学術集会
    • Place of Presentation
      千葉市
    • Data Source
      KAKENHI-PROJECT-24591454
  • [Presentation] The GITR-GITR ligand pathway acts as a mediator of cutaneous DC migration and promotes T cell-mediated immunity.2010

    • Author(s)
      Kamimura Y, Piao J, Hashiguchi M, Azuma M
    • Organizer
      14th ICI
    • Place of Presentation
      Kobe, Japan
    • Data Source
      KAKENHI-PROJECT-20249075
  • [Presentation] Triggering receptor expressed on myeloid cells-like transcript 2(TLT-2) is a counter-receptor for B7-H3 and enhances T cell responses in mice and humans.2010

    • Author(s)
      Hashiguchi M, Kobori H, Ritprajak P, Kamimura Y, Azuma M
    • Organizer
      14th ICI
    • Place of Presentation
      Kobe, Japan
    • Data Source
      KAKENHI-PROJECT-20249075
  • [Presentation] Triggering receptor expressed on myeloid cells-liketranscript 2(TLT-2) is a counter-receptor for B7-H3 and enhances T cell responses in mice and humans2010

    • Author(s)
      Hashiguchi M.
    • Organizer
      14th International Congress of Immunology
    • Place of Presentation
      Kobe, Japan
    • Data Source
      KAKENHI-PROJECT-20249075
  • [Presentation] Keratinocyte-associated B7-H1 directly regulates cutaneous effector CD8+ T cell responses.2010

    • Author(s)
      Ritprajak P, Hashiguchi M, Azuma M
    • Organizer
      14th ICI
    • Place of Presentation
      Kobe
    • Data Source
      KAKENHI-PROJECT-20249075
  • [Presentation] Triggering receptor expressed on myeloid cells-like transcript 2 (TLT-2) is a counter-receptor for B7-H3 and enhances T cell responses in mice and humans.2010

    • Author(s)
      Hashiguchi M, Kobori H, Ritprajak P, Kamimura Y, Azuma M
    • Organizer
      14th ICI
    • Place of Presentation
      Kobe
    • Data Source
      KAKENHI-PROJECT-20249075
  • [Presentation] B7-H1 on epidermal keratinocytes downregulates skin inflammation, but promotes squamous cell carcinoma formation.2010

    • Author(s)
      Cao Y, Zhang L, Ritprajak P, Hashiguchi M, Hase H, Azuma M
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20249075
  • [Presentation] Enhancement of effector CD8^+ T cell function by tumor-associated B7-H3 and modulation of its counter receptor triggering receptor expressed on myeloid cell-like transcript 2 (TLT-2) at tumor sites.2010

    • Author(s)
      Kobori H, Hashiguchi M, Azuma M
    • Organizer
      14^<th> ICI
    • Place of Presentation
      Kobe, Japan
    • Data Source
      KAKENHI-PROJECT-20249075
  • [Presentation] Antibodies against B7-DC with differential binding properties exert opposite effects : Implication of dual functions in PD -1 and B7-DC interactions.2010

    • Author(s)
      Azuma M, Ritprajak P, Akiba H, Yagita H, Okumura K, Hashiguchi M
    • Organizer
      14th ICI
    • Place of Presentation
      Kobe, Japan
    • Data Source
      KAKENHI-PROJECT-20249075
  • [Presentation] Overexpression of B7-H1 on epidermal keratinocytes promotes squamous cell carcinoma formation.2010

    • Author(s)
      Cao Y, Zhang L, Ritprajak P, Hashiguchi M, Azuma M
    • Organizer
      14^<th> ICI
    • Place of Presentation
      Kobe, Japan
    • Data Source
      KAKENHI-PROJECT-20249075
  • [Presentation] Triggering receptor expressed on myeloid cells-like transcript 2 (TLT-2) is a counter-receptor for B7-H32010

    • Author(s)
      M.Hashiguchi
    • Organizer
      The 14th International Congress of Immunology
    • Place of Presentation
      神戸
    • Year and Date
      2010-08-27
    • Data Source
      KAKENHI-PROJECT-21592385
  • [Presentation] Triggering receptor expressed on myeloid cells-like transcript 2 (TLT-2) is a counter-receptor for B7-H3 and enhances T cell responses in mice and humans2010

    • Author(s)
      Hashiguchi M.
    • Organizer
      14th International Congress of Immunology
    • Place of Presentation
      Kobe, Japan
    • Data Source
      KAKENHI-PUBLICLY-22021016
  • [Presentation] Overexpression of B7-H1 on epidermal keratinocytes promotes squamous cell carcinoma2010

    • Author(s)
      Cao Y, Zhang L, Ritprajak P, Hashiguchi M, Azuma M
    • Organizer
      97th AAI Annual Meeting, American Association of Immunologists, Immunology 2010
    • Place of Presentation
      Baltimore, USA
    • Data Source
      KAKENHI-PROJECT-20249075
  • [Presentation] Enhancement of effector CD8^+T cell function by tumor-associated B7-H3 and modulation of its counter receptor triggering receptor expressed on myeloid cell-like transcript 2(TLT-2) at tumor sites2010

    • Author(s)
      H. Kobori, M Hashiguchi, M. Azuma
    • Organizer
      14th International Congress of Immunology
    • Place of Presentation
      Kobe, Japan
    • Year and Date
      2010-08-26
    • Data Source
      KAKENHI-PROJECT-21592385
  • [Presentation] Triggering receptor expressed on myeloid cells-like transcript 2(TLT-2) is a counter-receptor for B7-H3 and enhances T cell responses in mice and humans2010

    • Author(s)
      M. Hashiguchi, H. Kobori, P. Ritprajak, Y. Kamimura, M. Azuma
    • Organizer
      14th International Congress of Immunology
    • Place of Presentation
      Kobe, Japan
    • Year and Date
      2010-08-26
    • Data Source
      KAKENHI-PROJECT-21592385
  • [Presentation] Triggering receptor expressed on myeloid cells-like transcript 2 (TLT-2) is a counter-receptor for B7-H3 and enhances Tcell responses in mice and humans2010

    • Author(s)
      Hashiguchi M.
    • Organizer
      14th International Congress of Immunology
    • Place of Presentation
      Kobe, Japan
    • Data Source
      KAKENHI-PROJECT-20249075
  • [Presentation] Analyses of anti-tumor immunity enhanced by a B7-H3 costimulator.2009

    • Author(s)
      Kobori H, Hashiguchi M, Piao J, Azuma M
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-20249075
  • [Presentation] Tumor-infiltrating CD8+ T cells express TLT-2, a counter receptor for B7-H3 and B7-H3-transduced tumors preferentially augment effector function of CD8^+ T cells2009

    • Author(s)
      H.Kobori, M.Hashiguchi, M.Azuma.
    • Organizer
      日本免疫学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2009-12-03
    • Data Source
      KAKENHI-PROJECT-21592385
  • [Presentation] Tumor-infiltrating CD8^+T cells express TLT-2, a counter receptor for B7-H3 and B7-H3-transduced tumors preferentially augment effector function of CD8^+T cells2009

    • Author(s)
      H. Kobori, M. Hashiguchi, M. Azuma
    • Organizer
      日本免疫学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2009-12-03
    • Data Source
      KAKENHI-PROJECT-21592385
  • [Presentation] Roles of keratinocyte-associated B7-H1 in squamous cell carcinoma formation and growth of tumor cells.2009

    • Author(s)
      Cao Y, Hashiguchi M, Azuma M
    • Organizer
      第39回日本免疫学会
    • Place of Presentation
      大阪国際会議場
    • Data Source
      KAKENHI-PROJECT-20249075
  • [Presentation] Mechanisms of effective inhibition by topical application of CD86 siRNA treatment in allergic skin disease.2009

    • Author(s)
      Kamimura Y, Ritprajak P, Hashiguchi M, Azuma M
    • Organizer
      第39回日本免疫学会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20249075
  • [Presentation] Tumor-infiltrating CD8^+ T cells express TLT-2, a counter receptor for B7-H3 and B7-H3-transeduced tumors preferentially augment effector function of CD8+ T cells.2009

    • Author(s)
      Kobori H, Hashiguchi M, Piao J, Azuma M
    • Organizer
      第39回日本免疫学会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20249075
  • [Presentation] Analyses of anti-tumor immunity enhanced by a B7-H3 costimulator2009

    • Author(s)
      H. Kobori, M. Hashiguchi, M. Azuma
    • Organizer
      日本癌学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2009-10-02
    • Data Source
      KAKENHI-PROJECT-21592385
  • [Presentation] Binding property, expression, and function of human TLT2, a counter-receptor for B7-H32009

    • Author(s)
      Hashiguchi M, Kobori H, Azuma M
    • Organizer
      第39回日本免疫学会
    • Place of Presentation
      大阪国際会議場
    • Data Source
      KAKENHI-PROJECT-20249075
  • [Presentation] Binding property, expression, and function of human TLT2, a counter-receptor for B7-H32009

    • Author(s)
      M. Hashiguchi, H. Kobori, M. Azuma
    • Organizer
      日本免疫学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2009-12-03
    • Data Source
      KAKENHI-PROJECT-21592385
  • [Presentation] Enhancement of T-cell-mediated anti-tumor immunity via the ectopically expressed GITR ligand on tumors.2009

    • Author(s)
      Piao J, Kamimura Y, Cao Y, Hashiguchi M, Azuma M
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-20249075
  • [Presentation] Binding property, expression, and function of human TLT2,a counter-receptor for B7-H3.2009

    • Author(s)
      Hashiguchi M, Kobori H, Azuma M
    • Organizer
      第39回日本免疫学会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20249075
  • [Presentation] Roles of keratinocyte-associated B7-H1 in squamous cell carcinoma formation and growth of tumor cells.2009

    • Author(s)
      Cao Y, Hashiguchi M, Azuma M
    • Organizer
      第39回日本免疫学会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20249075
  • [Presentation] Enhancement of T cell-mediated anti-tumor immunity via the ectopically expressed GITRL on tumors.2009

    • Author(s)
      Piao J, Kamimura Y, Hashiguchi M, Cao Y, Azuma M
    • Organizer
      第39回日本免疫学会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20249075
  • [Presentation] Tumor-associated B7-H3 augments cytotoxicity of CD8+ T cells at effector phase.2008

    • Author(s)
      Kobori H, Hashiguchi M, Piao J, Azuma M
    • Organizer
      第38回日本免疫学会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-20249075
  • [Presentation] GITR-GITRL pathway modulates migrating capacity of cutaneous DCs in the skin.2008

    • Author(s)
      Kamimura Y, Cao Y, Hashiguchi M, Azuma M
    • Organizer
      第38回日本免疫学会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-20249075
  • [Presentation] Triggering receptor expressed on myeloid cell-like transcript 2(TLT-2)is a counter-receptor for B7-H3 and enhances T cell responses2008

    • Author(s)
      Hashiguchi, M., Kobori, H., Ritprajak, P., Kamimura, Y., Azuma, M.
    • Organizer
      日本免疫学会学術集会
    • Place of Presentation
      京都
    • Year and Date
      2008-12-03
    • Data Source
      KAKENHI-PROJECT-19592168
  • [Presentation] GITRリガンド共刺激はCD4 T細胞のエフェクター機能と制御性機能の両者を活性化する2008

    • Author(s)
      Igarashi H, Cao Y, Piao J, Kamimura Y, Hashiguchi M, Azuma M
    • Organizer
      第38回日本免疫学会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-20249075
  • [Presentation] Topical application of cream emulsified CD86 siRNA ameliorates allergic skin disease by targeting cutaneous dendritic cells2008

    • Author(s)
      Ritprajak P, Hashiguchi M, Azuma M
    • Organizer
      38回日本免疫学会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-20249075
  • [Presentation] Topical application of cream emulsified CD86 siRNA ameliorates allergic skin disease by targeting cutaneous dendritic cells.2008

    • Author(s)
      Ritprajak P, Hashiguchi M, Azuma M
    • Organizer
      第38回日本免疫学会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-20249075
  • [Presentation] Tumor-associated B7-H3 augments cytotoxicity of CD8^+ T cells at effector phase2008

    • Author(s)
      Kobori H, Hashiguchi M, Azuma M, et al.
    • Organizer
      第38回日本免疫学会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-20249075
  • [Presentation] Triggering receptor expressed on myeloid cell-like transcript 2 (TLT-2)is acounter-receptor for B7-H3 and enhances T cell responses2008

    • Author(s)
      Hashiguchi, M., Kobori, H., Ritprajak, P., Kamimura, Y., Azuma, M.
    • Organizer
      日本免疫学会学術集会
    • Place of Presentation
      京都
    • Year and Date
      2008-03-12
    • Data Source
      KAKENHI-PROJECT-19592168
  • [Presentation] CD28 costimulation affects both susceptibility of effector T cells to regulatory T cells and inhibitory function of Treg.2008

    • Author(s)
      Cao Y, Kamimura Y, Hashiguchi M, Azuma M
    • Organizer
      第38回日本免疫学会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-20249075
  • [Presentation] B7-H3 upregulates immune responeses through the ligation with the B7-H3 receptor2007

    • Author(s)
      M. Hashiguchi, H. Kobori, P, Ritprajak, J. Piao, M. Azuma
    • Organizer
      American Association of Immunologist
    • Place of Presentation
      Miami Beach, Florida,USA
    • Year and Date
      2007-05-20
    • Data Source
      KAKENHI-PROJECT-19592168
  • [Presentation] B7-H3 upregulates immune responeses through the ligation with the B7-H3 receptor2007

    • Author(s)
      Hashiguchi, M., Kobori, H., Ritprajak,P., Piao, J., Azuma, M.
    • Organizer
      American Association of Immunologist
    • Place of Presentation
      Miami Beach, Florida, USA
    • Year and Date
      2007-05-20
    • Data Source
      KAKENHI-PROJECT-19592168
  • [Presentation] NF-κB downregulates IL-5 production via upregulation of T-box proteins

    • Author(s)
      Masaaki Hashiguchi, Hidefumi Kojima, Yuji Kashiwakura, Yumiko Kanno, Tetsuji Kobata
    • Organizer
      日本免疫学会学術集会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-24580196
  • [Presentation] IL-7 is a principal factor for HIF-1α regulated pro-B development

    • Author(s)
      Kanno Y, Kashiwakura T, Hashiguchi M, Kobata T, Kojima H.
    • Organizer
      第41回日本免疫学会学術集会
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Data Source
      KAKENHI-PROJECT-24591454
  • [Presentation] Characterization of activated CD4+ CD25+ regulatory T cells during immune responses

    • Author(s)
      Kojima H, Kanno Y, Kashiwakura Y, Hashiguchi M, Kobata T.
    • Organizer
      第41回日本免疫学会学術集会
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Data Source
      KAKENHI-PROJECT-24591454
  • [Presentation] IL-5 is produced by a novel subset of innate lymphoid cell with phenotypes of Lin^- Thy1.2^low-int CD25^+ IL-33Rα^+ in Peyer’s patches

    • Author(s)
      Masaaki Hashiguchi, Yuji Kashiwakura, Yumiko Kanno, Hidefumi Kojima, Tetsuji Kobata
    • Organizer
      日本免疫学会学術集会
    • Place of Presentation
      幕張
    • Data Source
      KAKENHI-PROJECT-24580196
  • [Presentation] Peripheral CD4+ CD25+ regulatory T cell survival is regulated by a combination of CD2 stimuli and the interaction with stromal cells

    • Author(s)
      Kashiwakura Y, Kanno Y, Hashiguchi M, Kobata T, Kojima H.
    • Organizer
      第41回日本免疫学会学術集会
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Data Source
      KAKENHI-PROJECT-24591454
  • 1.  AZUMA Miyuki (90255654)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 57 results
  • 2.  HASE Hidenori (70332997)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 3.  小園 裕子 (30197107)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  KOBAYASHI Ayano
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 5.  KOBATA Tetsuji (10205445)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 12 results
  • 6.  KASHIWAKURA Yuji (40382890)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 12 results
  • 7.  大野 建州 (80435635)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  神村 洋介 (40549929)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 9.  岩井 佳子 (90362467)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 10.  鍔田 武志 (80197756)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  TASAKU Yumi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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