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Yamamoto Hideki  山本 英樹

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YAMAMOTO Hideki  山本 英樹

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Researcher Number 20372691
Other IDs
Affiliation (Current) 2025: 滋慶医療科学大学, 医療科学部, 教授
Affiliation (based on the past Project Information) *help 2022 – 2023: 大阪大学, 大学院医学系研究科, 招へい教授
2020 – 2021: 大阪大学, 医学系研究科, 招へい教授
2016: 大阪大学, 医学系研究科, 准教授
2011 – 2015: 大阪大学, 医学(系)研究科(研究院), 准教授
2011: 大阪大学, 大学院・医学系研究科, 准教授 … More
2009 – 2011: 大阪大学, 医学系研究科, 准教授
2007 – 2009: 広島大学, 大学院・医歯薬学総合研究科, 准教授
2004 – 2006: Hiroshima University, Graduate School of Biomedical Sciences, Research Associate, 大学院医歯薬学総合研究科, 助手
2004: Hiroshima University, Graduate School of Biomedical Sciences, Research Associate, 大学院・医歯薬学総合研究科, 助手 Less
Review Section/Research Field
Principal Investigator
General medical chemistry / Basic Section 48040:Medical biochemistry-related / Biological Sciences / Pathological medical chemistry
Except Principal Investigator
General medical chemistry / Biological Sciences
Keywords
Principal Investigator
Wntシグナル / Wnt / 受容体 / LRP6 / 細胞内トラフィック / 小胞輸送 / 翻訳後修飾 / クラスリン / Wnt11 / Wnt5a … More / Frizzled / エンドサイトーシス / 分泌タンパク質 / 細胞応答 / 細胞膜 / 小胞体 / LDL / ガレクチン / AP2 / AP1 / 極性分泌 / 糖鎖修飾 / Wntless / 細胞内小胞輸送 / Wntシグナル経路 / Plk1 / 紡錘体形成 / 細胞分裂 / CHMP4B / Frizzled2 / Ror2 / Dvl2 / 細胞質分裂 / LRP6受容体 / Frizzled受容体 / Dkk1 / Rac / 分子病態学 / リン酸化 / カベオリン / β-カテニン / Axin … More
Except Principal Investigator
Wnt / エンドサイトーシス / GSK-3 / β-カテニン / 転移 / がん / conditioned medium / β-catenin / Tcf / 受容体 / PIASy / PKA / 前立腺癌 / インテグリン / Wnt5a / 極性 / シグナル伝達 / gycosylation / lipidation / Rho-kinase / endocytosis / PC12細胞 / Rhoキナーゼ / ダイナミン / LRP / Frizzled / 糖質修飾 / 脂質修飾 / Rho-キナーゼ / sumoylation / phosphorylation / wnt signal / metastasis / cancer / Rog1 / Rsp5 / Bul / Axin / ストレス応答 / 蛋白質リン酸化酵素PP2A / カゼインキナーゼI / Wntシグナル伝達経路 / Axam / カゼインキナーゼ / 癌 / 蛋白質分解 / APC / Tcf-4 / ユビキチン化 / SUMO化 / リン酸化 / Wntシグナル / クラスリン / リピッドラフト / 接着斑 / Dkkl / 紡錘糸 / MMP / 細胞分裂期 / Dvl / エクトドメイン / β-カテニン非依存性経路 / β-カテニン依存性経路 / グリピカン / ヘパラン硫酸プロテオグリカン / h-prune / SUMO / 胃がん / 翻訳後修飾 / Wnt-5a / JunD / 細胞運動 / ラミニン5γ2 / 細胞周期 / 細胞接着斑 / 胃癌 / がん抑制遺伝子 / がん遺伝子 / 接着 / 分化 Less
  • Research Projects

    (10 results)
  • Research Products

    (95 results)
  • Co-Researchers

    (10 People)
  •  Regulation of signal response through a novel DKK1 receptor "CKAP4"Principal Investigator

    • Principal Investigator
      Yamamoto Hideki
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 48040:Medical biochemistry-related
    • Research Institution
      Osaka University
  •  Regulation of membrane traffic of Wnt and its receptorsPrincipal Investigator

    • Principal Investigator
      Yamamoto Hideki
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Osaka University
  •  Selective activation of Wnt signaling pathway using with purified Wnt proteinsPrincipal Investigator

    • Principal Investigator
      YAMAMOTO Hideki
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Osaka University
  •  細胞分裂期におけるWntシグナル因子Dvlによる紡錘体形成の制御機構Principal Investigator

    • Principal Investigator
      山本 英樹
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  Regulation of signaling network and cellular responses by Wnt

    • Principal Investigator
      KIKUCHI Akira
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      General medical chemistry
    • Research Institution
      Osaka University
  •  Regulation of Wnt signaling by different endocytic pathwayPrincipal Investigator

    • Principal Investigator
      YAMAMOTO Hideki
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Osaka University
      Hiroshima University
  •  Abnormal Differentiation in Cancer Cells and Intracellular Signaling

    • Principal Investigator
      KIKUCHI Akira
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Hiroshima University
  •  エンドサイトーシスによるWntシグナル伝達経路の制御機構の解析Principal Investigator

    • Principal Investigator
      山本 英樹
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Hiroshima University
  •  Regulation of the Wnt signal by receptor-mediated endocytosis

    • Principal Investigator
      KIKUCHI Akira
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      HIROSHIMA UNIVERSITY
  •  Identification of intercellular signal transduction molecules and analysis of their functional abnormality in human cancer

    • Principal Investigator
      KIKUCHI Akira
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      HIROSHIMA UNIVERSITY

All 2023 2022 2021 2020 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2003 2001 Other

All Journal Article Presentation Book

  • [Book] WntシグナルにおけるFrizzled受容体の活性化機構2016

    • Author(s)
      山本 英樹, 菊池 章
    • Total Pages
      9
    • Publisher
      医歯薬出版株式会社
    • Data Source
      KAKENHI-PROJECT-26460365
  • [Book] サイトカイン・増殖因子キーワード事典2015

    • Author(s)
      菊池 章、山本 英樹
    • Total Pages
      3
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-26460365
  • [Book] The Lipid2014

    • Author(s)
      山本 英樹、菊池 章
    • Total Pages
      7
    • Publisher
      メディカルレビュー社
    • Data Source
      KAKENHI-PROJECT-26460365
  • [Book] 極性化上皮細胞におけるWnt分泌制御2013

    • Author(s)
      山本 英樹
    • Total Pages
      8
    • Publisher
      細胞工学(秀潤社)
    • Data Source
      KAKENHI-PROJECT-23590333
  • [Book] 極性化上皮細胞におけるWntの分泌制御2013

    • Author(s)
      山本 英樹、菊池 章
    • Total Pages
      8
    • Publisher
      秀潤社
    • Data Source
      KAKENHI-PROJECT-23590333
  • [Book] 実験医学2005

    • Author(s)
      山本 英樹 他2名
    • Total Pages
      6
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-17790192
  • [Journal Article] CKAP4 is a potential exosomal biomarker and therapeutic target for lung cancer2023

    • Author(s)
      Nagoya Akihiro、Sada Ryota、Kimura Hirokazu、Yamamoto Hideki、Morishita Koichi、Miyoshi Eiji、Morii Eiichi、Shintani Yasushi、Kikuchi Akira
    • Journal Title

      Translational Lung Cancer Research

      Volume: 12 Issue: 3 Pages: 408-426

    • DOI

      10.21037/tlcr-22-571

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K15511, KAKENHI-PROJECT-21H04797, KAKENHI-PROJECT-21K19407, KAKENHI-PROJECT-20K16330, KAKENHI-PROJECT-20K17746, KAKENHI-PROJECT-20K07311, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-23K24228
  • [Journal Article] The Dickkopf1 and FOXM1 positive feedback loop promotes tumor growth in pancreatic and esophageal cancers2021

    • Author(s)
      Kimura Hirokazu、Sada Ryota、Takada Naoki、Harada Akikazu、Doki Yuichiro、Eguchi Hidetoshi、Yamamoto Hideki、Kikuchi Akira
    • Journal Title

      Oncogene

      Volume: 40 Issue: 26 Pages: 4486-4502

    • DOI

      10.1038/s41388-021-01860-z

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07311, KAKENHI-PROJECT-21K19407, KAKENHI-PROJECT-20K16330, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-21H04797
  • [Journal Article] Active and water-soluble form of lipidated Wnt protein is maintained by a serum glycoprotein afamin/α-albumin.2016

    • Author(s)
      Mihara, E., Hirai, H., Yamamoto, H., Tamura-Kawakami, K., Matano, M., Kikuchi, A., Sato, T., and Takagi, J.
    • Journal Title

      Elife

      Volume: 5 Pages: 1-19

    • DOI

      10.7554/elife.11621

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26460365, KAKENHI-PROJECT-15K15297, KAKENHI-ORGANIZER-23112001, KAKENHI-PLANNED-23112004, KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111006, KAKENHI-PLANNED-26115007, KAKENHI-PROJECT-25250018, KAKENHI-PROJECT-26860528, KAKENHI-PROJECT-26293177, KAKENHI-WRAPUP-16H01696, KAKENHI-PROJECT-16K09325
  • [Journal Article] Wnt5b-associated Exosomes promote cell proliferation and migration in a cancer cell context2016

    • Author(s)
      Harada, T., Yamamoto, H., Kishida, S., Kishida, M., Awada, C., Takao, T., and Kikuchi, A.
    • Journal Title

      Cancer Sci.

      Volume: 108 Issue: 1 Pages: 42-52

    • DOI

      10.1111/cas.13109

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26460365, KAKENHI-PROJECT-16H06374
  • [Journal Article] Wnt5a promotes cancer cell invasion and proliferation by receptor-mediated endocytosis-dependent and -independent mechanisms, respectively2015

    • Author(s)
      Shojima, K., Sato, A., Hanaki, H., Tsujimoto, I., Nakamura, M., Hattori, K., Sato, Y., Dohi, K., Hirata, M., Yamamoto, H., and Kikuchi, A.
    • Journal Title

      Sci. Rep.

      Volume: 5 Issue: 1 Pages: 8042-8042

    • DOI

      10.1038/srep08042

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-ORGANIZER-23112001, KAKENHI-PLANNED-23112004, KAKENHI-PROJECT-24590378, KAKENHI-PROJECT-25250018, KAKENHI-PROJECT-26460365
  • [Journal Article] A. Basolateral secretion of Wnt5a in polarized epithelial cells is required for apical lumen formation2015

    • Author(s)
      Yamamoto, H., Awada, C., Matsumoto, S., Kaneiwa, T., Sugimoto, T., Takao, T., and Kikuchi
    • Journal Title

      J. Cell Sci.

      Volume: 128 Pages: 1051-1063

    • DOI

      10.1242/jcs.163683

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25860211, KAKENHI-PROJECT-15K08272, KAKENHI-PROJECT-26460365, KAKENHI-ORGANIZER-23112001, KAKENHI-PLANNED-23112004, KAKENHI-PROJECT-25250018
  • [Journal Article] The apical and basolateral secretion of Wnt11 and Wnt3a in polarized epithelial cells is regulated by distinct mechanisms.2013

    • Author(s)
      Yamamoto, H., Awada, C., Hanaki, H., Sakane, H., Tsujimoto, I., Takahashi, Y., Takao, T., and Kikuchi, A.
    • Journal Title

      J. Cell Sci.

      Volume: 126 Pages: 2931-2943

    • DOI

      10.1242/jcs.126052

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-23112001, KAKENHI-PLANNED-23112004, KAKENHI-PROJECT-23590333, KAKENHI-PROJECT-24790280, KAKENHI-PROJECT-25250018
  • [Journal Article] Apicobasal secretion of Wnt11 and Wnt3a in polarized epithelial cells is regulated by distinct mechanisms2013

    • Author(s)
      Yamamoto, H. et. al
    • Journal Title

      J. Cell Sci.

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590333
  • [Journal Article] An Wnt5a-antibody suppresses metastasis of gastric cancer cells in vivo by inhibiting receptor-mediated endocytosis2012

    • Author(s)
      Hanaki, H., Yamamoto, H., Sakane, H., Matsumoto, S., Ohdan, H., Sato, A., and Kikuchi, A
    • Journal Title

      Mol. Cancer Ther

      Volume: 11 Pages: 298-307

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249017
  • [Journal Article] Localization of glypican-4 in different membrane microdomains is involved in the regulation of Wnt signaling2012

    • Author(s)
      Sakane, H., et.al.
    • Journal Title

      J.Cell Sci.

      Volume: 125 Issue: 2 Pages: 449-460

    • DOI

      10.1242/jcs.091876

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249017, KAKENHI-PUBLICLY-22019025, KAKENHI-PROJECT-22770127, KAKENHI-PROJECT-22790316, KAKENHI-ORGANIZER-23112001, KAKENHI-PROJECT-23590333, KAKENHI-PROJECT-23650594, KAKENHI-PROJECT-23790333, KAKENHI-PROJECT-24590378, KAKENHI-PLANNED-23112004
  • [Journal Article] Wnt5a : its signaling, functions, and implication in diseases2012

    • Author(s)
      Kikuchi, A., Yamamoto, H., Sato, A., and Maysimoto, S
    • Journal Title

      Acta physiol

      Volume: 204 Pages: 17-33

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249017
  • [Journal Article] Localization of glypican-4 in different membrane microdomains is involved in the regulation of Wnt signaling2012

    • Author(s)
      Sakane, H., Yamamoto, H., Matsumoto, S., Sato, A., and Kikuchi, A
    • Journal Title

      J. Cell Sci

      Volume: 125 Pages: 449-460

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249017
  • [Journal Article] An Wnt5a-antibody suppresses metastasis of gastric cancer cells in vivo by inhibiting receptor-mediated endocytosis2012

    • Author(s)
      Hanaki, H., et.al.
    • Journal Title

      Mol.Cancer Ther.

      Volume: 11 Issue: 2 Pages: 298-307

    • DOI

      10.1158/1535-7163.mct-11-0682

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249017, KAKENHI-PUBLICLY-22019025, KAKENHI-PROJECT-22770127, KAKENHI-PROJECT-22790316, KAKENHI-ORGANIZER-23112001, KAKENHI-PROJECT-23590333, KAKENHI-PROJECT-23790333, KAKENHI-PROJECT-24590378, KAKENHI-PLANNED-23112004
  • [Journal Article] Wnt5a : its signaling, functions, and implication in diseases2012

    • Author(s)
      Kikuchi, A., et.al.
    • Journal Title

      Acta Physiol.

      Volume: 204 Issue: 1 Pages: 17-33

    • DOI

      10.1111/j.1748-1716.2011.02294.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249017, KAKENHI-PROJECT-22770127, KAKENHI-ORGANIZER-23112001, KAKENHI-PROJECT-23590333, KAKENHI-PROJECT-23650594, KAKENHI-PROJECT-24590378, KAKENHI-PLANNED-23112004
  • [Journal Article] New insights into the mechanism of Wnt signaling pathway activation2011

    • Author(s)
      Kikuchi, A., Yamamoto, H., Sato, A., Mastumoto, S
    • Journal Title

      Int. Rev. Cell. Mol. Biol

      Volume: 291 Pages: 21-71

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249017
  • [Journal Article] New insights into the mechanism of Wnt signaling pathway activation2011

    • Author(s)
      Kikuchi, A
    • Journal Title

      Int Rev Cell Mol Biol.

      Volume: 291 Pages: 21-71

    • DOI

      10.1016/b978-0-12-386035-4.00002-1

    • ISBN
      9780123860354
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249017, KAKENHI-PUBLICLY-22019025, KAKENHI-PROJECT-22770127, KAKENHI-ORGANIZER-23112001, KAKENHI-PLANNED-23112004, KAKENHI-PROJECT-23590333, KAKENHI-PROJECT-23650594, KAKENHI-PROJECT-23790333
  • [Journal Article] Waif1/5T4 inhibits Wnt/β-catenin signaling and activates noncanonical Wnt pathways by modifying LRP6 subcellular localization2011

    • Author(s)
      Kagermeier-Schenk, B., et.al.
    • Journal Title

      Dev.Cell.

      Volume: 21 Issue: 6 Pages: 1129-1143

    • DOI

      10.1016/j.devcel.2011.10.015

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249017, KAKENHI-PUBLICLY-22019025, KAKENHI-ORGANIZER-23112001, KAKENHI-PLANNED-23112004, KAKENHI-PROJECT-23590333
  • [Journal Article] The transmembrane protein Waif1/ 5T4 inhibits Wnt/β-catenin signaling and activates noncanonical Wnt pathways by modifying LRP6 subcellular localization2011

    • Author(s)
      Kagermeier-Schenk, B., Wehner, D., Ozhan-Kizil, G., Yamamoto, H., Jian Li, Kirchner, K., Hoffmann, C., Stern, P., Kikuchi, A., Schambony, A., and Weidinger, G
    • Journal Title

      Dev. Cell

      Volume: 21 Pages: 1129-1143

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249017
  • [Journal Article] The transmembrane protein Waif1/5T4 inhibits Wnt/β-catenin signaling and activates noncanonical Wnt pathways by modifying LRP6 subcellular localization2011

    • Author(s)
      Kagermeier-Schenk, B., Wehner, D., Ö z h a n -Kizil, G. Yamamoto, H., Li, J., Kirchner, K., Hoffmann, C., Stern, P., Kikuchi, A., Schambony, A., Weidinger, G.
    • Journal Title

      Dev. Cell

      Volume: 21 Issue: 4 Pages: 1129-1143

    • DOI

      10.1016/j.devcel.2013.07.020

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590333
  • [Journal Article] Wnt5a signaling is involved in the aggressiveness of prostate cancer and expression of metalloproteinase.2010

    • Author(s)
      Yamamoto,H., Oue,N., Sato,A., Hasegawa,Y., Matsubara,A., Yamamoto,H., Yasui,W., Kikuch,A
    • Journal Title

      Oncogene 29

      Pages: 2036-2046

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014066
  • [Journal Article] Wnt5a signaling is involved in the aggressiveness of prostate cancer and expression of metalloproteinase.2010

    • Author(s)
      Yamamoto, H., et.al.
    • Journal Title

      Oncogene

      Volume: 29 Pages: 2036-2046

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014066
  • [Journal Article] Wnt5a signaling is involved in the aggressiveness of prostate cancer and expression of metalloproteinase.2010

    • Author(s)
      Yamamoto, H., Oue, N., Sato, A., Hasegawa, Y., Yamamoto, H., Matsubara, A., Yasui, W., Kikuchi, A.
    • Journal Title

      Oncogene 29

      Pages: 2036-2046

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790320
  • [Journal Article] Wnt5a signaling is involved in the aggressiveness of prostate cancer and expression of metalloproteinase2010

    • Author(s)
      Yamamoto, H., Oue, N., Sato, A., Hasegawa, Y., Matsubara, A., Yamamoto, H., Yasui, W., and Kikuch, A
    • Journal Title

      Oncogene

      Volume: 29 Pages: 2036-2046

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249017
  • [Journal Article] Wnt5a regulates distinct signaling pathways by binding to Frizzled22010

    • Author(s)
      Sato, A., Yamamoto, H., Sakane, H., Koyama, H., and Kikuchi, A
    • Journal Title

      EMBO J

      Volume: 29 Pages: 41-54

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249017
  • [Journal Article] Wnt5a signaling is involved in the aggressiveness of prostate cancer and expression of metalloproteinase.2010

    • Author(s)
      Yamamoto, H., Kikuchi, A..
    • Journal Title

      Oncogene

      Volume: 29 Pages: 2036-2046

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249017
  • [Journal Article] Wnt5a signaling is involved in the aggressiveness of prostate cancer and expression of metalloproteinase2010

    • Author(s)
      Yamamoto, H., et al.
    • Journal Title

      Oncogene

      Volume: 29 Pages: 2036-2046

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-22019025
  • [Journal Article] LRP6 is internalized by Dkkl to suppress its phosphorylation in the lipid raft and is recycled for reuse.2010

    • Author(s)
      Sakane, H., Yamamoto, H., Kikuchi, A.
    • Journal Title

      J.Cell Sci. 123

      Pages: 360-368

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790320
  • [Journal Article] Wnt5a signaling is involved in the aggressiveness of prostate cancer and expression of metallonroteinase2010

    • Author(s)
      Yamamoto H, et al.
    • Journal Title

      Oncogene (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790320
  • [Journal Article] Wnt5a regulates distinct signaling pathways by binding to Frizzled2.2010

    • Author(s)
      Sato, A.,Yamamoto, H.,Sakane, H., Koyama, H., Kikuchi, A.
    • Journal Title

      EMBO J. 29

      Pages: 41-54

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790320
  • [Journal Article] LRP6 is internalized by Dkk1 to suppress its phosphorylation in the lipid raft and is recycled for reuse2010

    • Author(s)
      Sakane, H., Yamamoto, H., and Kikuchi, A
    • Journal Title

      J. Cell Sci

      Volume: 123 Pages: 360-368

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249017
  • [Journal Article] Wnt5a signaling is involved in the aggressiveness of prostate cancer and expression of metalloproteinase2010

    • Author(s)
      Yamamoto, H., et al.
    • Journal Title

      Oncogene

      Volume: 29 Pages: 2036-2046

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790320
  • [Journal Article] LRP6 is internalized by Dkk1 to suppress its phosphorylation in the lipid raft and is recycled for reuse.2010

    • Author(s)
      Sakane,H., Yamamoto,H., Kikuchi,A
    • Journal Title

      J.Cell Sci. 123

      Pages: 360-368

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014066
  • [Journal Article] Wnt5a regulates distinct signaling pathways by binding to Frizzled2.2010

    • Author(s)
      Sato,A., Yamamoto,H., Sakane,H., Koyama,H., Kikuchi,A
    • Journal Title

      EMBO J. 29

      Pages: 41-54

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014066
  • [Journal Article] Laminin γ2 mediates Wnt5a-induced invasion of Gastric Cancer Cells2009

    • Author(s)
      Yamamoto, H., et.al.
    • Journal Title

      Gastroenterology (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014066
  • [Journal Article] Laminin γ2 Mediates Wnt5a-induced Invasion of Gastric Cancer Cells.2009

    • Author(s)
      Yamamoto, H., et.al.
    • Journal Title

      Gastroenterology

      Volume: 137 Pages: 242-252

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014066
  • [Journal Article] Laminin・2 mediates Wnt5a-induced invasion of gastric cancer cells2009

    • Author(s)
      Yamamoto, H., Kitadai, . Y., Yamamoto, H., Oue, N., Ohdan, H., Yasui, W., and Kikuchi, A
    • Journal Title

      Gastroenterology

      Volume: 137 Pages: 242-252

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249017
  • [Journal Article] Laminin γ2 Mediates Wnt5a-induced Invasion of Gastric Cancer Cells.2009

    • Author(s)
      Yamamoto, H., et.al.
    • Journal Title

      Gastroenterology

      Volume: 137 Pages: 242-252

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249017
  • [Journal Article] Laminin・2 mediates Wnt5a-induced invasion of gastric cancer cells.2009

    • Author(s)
      Yamamoto,H., Kitadai,.Y., Yamamoto,H., Oue,N., Ohdan,H., Yasui,W., Kikuchi,A
    • Journal Title

      Gastroenterology 137

      Pages: 242-252

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014066
  • [Journal Article] Selective activation mechanisms of Wnt signaling pathways.2009

    • Author(s)
      Kikuchi,A., Yamamoto,H., Sato,A
    • Journal Title

      Trends Cell Biol. 19

      Pages: 119-129

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014066
  • [Journal Article] Selective activation of mechanisms of Wnt signaling pathways.2009

    • Author(s)
      Kikuchi, A.,Yamamoto, H.,and Sato, A.
    • Journal Title

      Trends Cell Biol. 19

      Pages: 119-129

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790320
  • [Journal Article] Laminin・2 mediates Wnt5a-induced invasion of Gastric Cancer Cells.2009

    • Author(s)
      Yamamoto, H.,Kitadai, Y.,Yamamoto, H., Oue, N., Ohdan, H., Yasui, W., Kikuchi, A.
    • Journal Title

      Gastroenterology 137

      Pages: 242-252

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790320
  • [Journal Article] Selective activation mechanisms of Wnt signaling pathways2009

    • Author(s)
      Kikuchi, A., Yamamoto, H., and Sato, A
    • Journal Title

      Trends Cell Biol

      Volume: 19 Pages: 119-129

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249017
  • [Journal Article] Laminin γ2 mediates Wnt5a-induced invasion of gastric cancer cells2009

    • Author(s)
      Yamamoto H, et al.
    • Journal Title

      Gastroenterology 137

      Pages: 242-252

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790320
  • [Journal Article] Wnt3a and Dkk1 regulate distinct internalization pathways of LRP6 to tune the activation of ・-catenin signaling.2008

    • Author(s)
      Yamamoto,H., Sakane,H., Yamamoto,H., Michiue,T., Kikuch,A
    • Journal Title

      Dev. Cell 15

      Pages: 37-48

    • Data Source
      KAKENHI-PROJECT-17014066
  • [Journal Article] Tumor formation due to abnormalities in the ・-catenin-independent pathway of Wnt signaling.2008

    • Author(s)
      Kikuchi,A. Yamamoto,H
    • Journal Title

      Cancer Sci. 99

      Pages: 202-208

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014066
  • [Journal Article] Wnt3a and Dkkl regulate internalization of LRP6 differently to tune β-catenin pathway・2008

    • Author(s)
      Yamamoto, H., et. al.
    • Journal Title

      Dev. Cell (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014066
  • [Journal Article] Wnt3a and Dkk1 regulate distinct internalization pathways of LRP6 to tune the activation of β-catenin signaling2008

    • Author(s)
      Yamamoto, H., et.al.
    • Journal Title

      Dev. Cell 15

      Pages: 37-48

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014066
  • [Journal Article] Tumor formation due to abnormalities in the β-catenin-independent pathway of Wnt siqnaling.2008

    • Author(s)
      Kikuchi, A. Yamamoto, H.
    • Journal Title

      Cancer Sci. 99

      Pages: 202-208

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014066
  • [Journal Article] Glycosylation and palmitoylation of Wnt-3a are coupled to produce an active form of Wnt-3a.2007

    • Author(s)
      Komekado,H., Yamamoto,H., Chiba,T., Kikuchi,A
    • Journal Title

      Genes Cells 12

      Pages: 521-534

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014066
  • [Journal Article] Wnt5a modulates glycogen synthase kinase 3 to induce phospshorylation of receptor tyrosine kinase Ror2.2007

    • Author(s)
      Yamamoto, H., et. al.
    • Journal Title

      Genes Cells 12

      Pages: 1215-1223

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014066
  • [Journal Article] Post-translational palmitoylation and glycosylation of Wnt-5a are necessary for its signaling.2007

    • Author(s)
      Kurayoshi,M., Yamamoto,H., Takada,S., Izumi,S., Kikuchi,A
    • Journal Title

      Biochem.J. 402

      Pages: 515-523

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014066
  • [Journal Article] Regulation of Wnt signaling by receptor-mediated endocytosis.2007

    • Author(s)
      Kikuchi,A. Yamamoto,H
    • Journal Title

      J.Biochem. 141

      Pages: 443-451

    • NAID

      10020099687

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014066
  • [Journal Article] Multiplicity of the interactions of Wnt proteins and their receptors.2007

    • Author(s)
      Kikuchi,A., Kishida,S., Yamamoto,H
    • Journal Title

      Cell.Signal. 19

      Pages: 659-671

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014066
  • [Journal Article] Caveolin is necessary for Wnt-3a-induced internalization of LRP6 and accumulation of ・-catenin.2006

    • Author(s)
      Yamamoto,H., Komekado,H., Kikuchi,A
    • Journal Title

      Dev.Cell 11

      Pages: 213-223

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014066
  • [Journal Article] Caveolin is necessary.for Wnt-3a-induced internalization of LRP6 and accumulation of β-catenin.2006

    • Author(s)
      Yamamoto, H. et al.
    • Journal Title

      Dev. Cell 11

      Pages: 213-223

    • Data Source
      KAKENHI-PROJECT-17014066
  • [Journal Article] Regulation of Wnt signaling by protein-protein interaction and post-translational modifications.2006

    • Author(s)
      Kikuchi,A., Kishida,S., Yamamoto,H
    • Journal Title

      Experi.&Mol.Med. 38

      Pages: 1-10

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014066
  • [Journal Article] Caveolin is necessary for Wnt-3a-dependent internalization of LRP6 and accumulation of β-catenin2006

    • Author(s)
      Hideki Yamamoto, et al.
    • Journal Title

      Dev. Cell 11・2

      Pages: 213-223

    • Data Source
      KAKENHI-PROJECT-17790192
  • [Journal Article] Expression of Wnt-5a is correlated with aggressiveness of gastric cancer by stimulating cell migration and invasion.2006

    • Author(s)
      Kurayoshi,M., Oue,N., Yamamoto,H., Kishida,M., Inoue,A., Asahara,T., Yasui,W., Kikuchi,A
    • Journal Title

      Cancer Res. 66

      Pages: 10439-10448

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014066
  • [Journal Article] SUMO-1 modification of PIASy, an E3 ligase, is necessary for PIASy-dependent activation of Tcf-4.2005

    • Author(s)
      Ihara,M., Yamamoto,H., Kikuchi,A
    • Journal Title

      Mol.Cell.Biol. 25

      Pages: 3506-3518

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17014066
  • [Journal Article] Sumoylation is involved in β-catenin-dependent activation of Tcf-4.2003

    • Author(s)
      Yamamoto, H.
    • Journal Title

      EMBO J. 22

      Pages: 2047-2059

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12219214
  • [Journal Article] Sumoylation is involved in β-catenin-dependent activation of Tcf-4.2003

    • Author(s)
      Yamamoto H.
    • Journal Title

      EMBO J. 22

      Pages: 2047-2059

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390094
  • [Journal Article] Inhibition of the Wnt signaling pathway by the PR61 subunit of protein phosphatase 2A.2001

    • Author(s)
      Yamamoto, H.
    • Journal Title

      J. Biol. Chem. 276

      Pages: 26875-26882

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12219214
  • [Presentation] DKK1受容体CKPA4の細胞内輸送制御の解析2023

    • Author(s)
      山本 英樹、佐田 遼太、菊池 章
    • Organizer
      第96回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-20K07311
  • [Presentation] 新規DKK1受容体CKPA4の細胞内輸送制御2022

    • Author(s)
      山本 英樹, 佐田 遼太, 菊池 章
    • Organizer
      第95回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-20K07311
  • [Presentation] DKK1受容体CKAP4による細胞応答制御2021

    • Author(s)
      山本 英樹
    • Organizer
      第94回日本生化学会大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K07311
  • [Presentation] Dynamic palmitoylation determines membrane microdomain localization of two DKK1 receptors CKAP4 and LRP6, and regulates DKK1 signaling2020

    • Author(s)
      山本 英樹, 佐田 遼太, 木村 公一, 菊池 章
    • Organizer
      第92回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-20K07311
  • [Presentation] 肝細胞におけるLDLによるLRP6の異なるエンドサイトーシス経路の制御機構2016

    • Author(s)
      山本英樹、梅田大介、松本真司、菊池章
    • Organizer
      第89回日本生化学会大会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-26460365
  • [Presentation] エキソソーム上のWnt5bは細胞環境に応じて、がん細胞の増殖と運動を制御する2016

    • Author(s)
      原田武志、山本英樹、菊池章
    • Organizer
      第89回日本生化学会大会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-26460365
  • [Presentation] Wnt5bの細胞外分泌機構とその生理機能の解析2015

    • Author(s)
      原田 武志, 山本 英樹, 菊池 章
    • Organizer
      日本生化学会
    • Place of Presentation
      神戸
    • Year and Date
      2015-12-03
    • Data Source
      KAKENHI-PROJECT-26460365
  • [Presentation] Wnt5aの極性分泌による上皮細胞の内腔形成制御機構2015

    • Author(s)
      山本 英樹, 粟田 ちひろ, 高尾 敏文, 菊池 章
    • Organizer
      日本生化学会
    • Place of Presentation
      神戸
    • Year and Date
      2015-12-03
    • Data Source
      KAKENHI-PROJECT-26460365
  • [Presentation] 翻訳後修飾によるWnt5aの細胞外分泌の制御機構2014

    • Author(s)
      杉本 崇行, 山本 英樹, 金岩 知之, 粟田 ちひろ, 高尾 敏文, 坂根 洋, 菊池 章
    • Organizer
      日本生化学会
    • Place of Presentation
      京都
    • Year and Date
      2014-10-17
    • Data Source
      KAKENHI-PROJECT-26460365
  • [Presentation] 極性化された上皮細胞におけるWntとその受容体の輸送制御機構2014

    • Author(s)
      山本 英樹, 金岩 知之, 粟田 ちひろ, 高尾 敏文, 菊池 章
    • Organizer
      日本生化学会
    • Place of Presentation
      京都
    • Year and Date
      2014-10-17
    • Data Source
      KAKENHI-PROJECT-26460365
  • [Presentation] 極性化された上皮細胞におけるWntの分泌制御機構2013

    • Author(s)
      山本英樹, 花木英明, 辻本育子, 金岩知之, 粟田ちひろ, 高尾敏文, 菊池章
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23590333
  • [Presentation] 翻訳後修飾によるWnt11の機能発現の制御2012

    • Author(s)
      山本英樹, 花木英明, 辻本育子, 粟田ちひろ, 高尾敏文, 菊池章
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-23590333
  • [Presentation] 翻訳後修飾によるWnt11蛋白質の機能発現の制御2012

    • Author(s)
      山本 英樹
    • Organizer
      生化学会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-23590333
  • [Presentation] 翻訳後修飾によるWnt蛋白質の機能発現の制御2011

    • Author(s)
      山本英樹
    • Organizer
      生化学会
    • Place of Presentation
      京都国際会館(京都府)
    • Year and Date
      2011-09-22
    • Data Source
      KAKENHI-PUBLICLY-22019025
  • [Presentation] 翻訳後修飾によるWnt蛋白質の機能発現の制御2011

    • Author(s)
      山本 英樹
    • Organizer
      生化学会
    • Place of Presentation
      京都国際会館(京都府)
    • Data Source
      KAKENHI-PROJECT-23590333
  • [Presentation] 翻訳後修飾によるWnt蛋白質の機能発現の制御2011

    • Author(s)
      山本英樹, 粟田ちひろ, 高尾敏文, 岸田昭世, 岸田想子, 菊池章
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23590333
  • [Presentation] Wnt5a-dependent activation of Rac through the internalization of Frizzled receptor2010

    • Author(s)
      山本英樹
    • Organizer
      第33回日本分子生物学会年会 第83回日本生化学会大会 合同大会
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2010-12-08
    • Data Source
      KAKENHI-PROJECT-21790320
  • [Presentation] Wnt5a-dependent activation of Rac throug the internalization of Frizzled receptor2010

    • Author(s)
      山本英樹、佐藤朗、坂根洋、菊池章
    • Organizer
      第83回日本生化学会大会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-21790320
  • [Presentation] Wnt5a-dependent activation of Rac through the internalization of Frizzled receptor2010

    • Author(s)
      山本英樹
    • Organizer
      第33回日本分子生物学会年会 第83回日本生化学会大会 合同大会
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2010-12-08
    • Data Source
      KAKENHI-PUBLICLY-22019025
  • [Presentation] 異なる受容体エンドサイトーシス経路を介するWntシグナル伝達の制御機構2009

    • Author(s)
      山本英樹、坂根洋、菊池章
    • Organizer
      第82回日本生化学会大会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-21790320
  • [Presentation] クラスリンを介するエンドサイトーシスによるWnt5a依存性のRacの活性化2009

    • Author(s)
      山本英樹
    • Organizer
      日本癌学会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2009-10-03
    • Data Source
      KAKENHI-PROJECT-21790320
  • [Presentation] 異なる受容体エンドサイトーシス経路を介するWntシグナル伝達の制御機構2009

    • Author(s)
      山本英樹
    • Organizer
      日本化学会
    • Place of Presentation
      神戸ポートビプホテル(神戸市)
    • Year and Date
      2009-10-25
    • Data Source
      KAKENHI-PROJECT-21790320
  • [Presentation] 脂質ラフトにおけるWntシグナルの活性制御2008

    • Author(s)
      山本英樹
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-10-28
    • Data Source
      KAKENHI-PROJECT-17014066
  • [Presentation] Wnt5aはlaminin-5γ2の発現を介して胃癌細胞の転移能を促進する2008

    • Author(s)
      山本英喜
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-10-28
    • Data Source
      KAKENHI-PROJECT-17014066
  • [Presentation] Expression of Wnt5a is correlated with aggressiveness of gastric and prostate cancer by stimulating cell migration and invasion.2007

    • Author(s)
      Kikuchi, A., Yamamoto,H
    • Organizer
      Traditional Wnt meeting.
    • Place of Presentation
      La Jolla. California, USA
    • Year and Date
      2007-06-22
    • Data Source
      KAKENHI-PROJECT-17014066
  • [Presentation] Expression of Wnt5a is correlated with aggressiveness of gastric and prostate cancer by stimulating cell miqration andinvasion.2007

    • Author(s)
      Kikuchi. A. Yamamoto. H.
    • Organizer
      Traditional Wnt meeting.
    • Place of Presentation
      La Jolla.California, USA
    • Year and Date
      2007-06-22
    • Data Source
      KAKENHI-PROJECT-17014066
  • [Presentation] 極性化された上皮細胞におけるWntの分泌制御機構

    • Author(s)
      山本 英樹, 花木 英明, 辻本 育子, 粟田 ちひろ, 高尾 敏文, 菊池 章
    • Organizer
      生化学会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-23590333
  • 1.  KIKUCHI Akira (10204827)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 30 results
  • 2.  HINO Shin-ichirou (00372699)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  SATO Akira (70464302)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 10 results
  • 4.  KISHIDA Michiko (40274089)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 5.  TAKAO Toshifumi (10197048)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 8 results
  • 6.  KISHIDA Shosei (50274064)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  小山 眞也 (00186834)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  安東 知子 (20294548)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  佐田 遼太 (60869783)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 10.  松本 真司
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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