Hirata Kunio 平田邦生

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HIRATA Kunio 平田邦生

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Researcher Number	20373524
Other IDs	https://orcid.org/0000-0002-1491-6509
Affiliation (Current)	2025: 国立研究開発法人理化学研究所, 放射光科学研究センター, 専任技師
Affiliation (based on the past Project Information) *help	2022 – 2024: 国立研究開発法人理化学研究所, 放射光科学研究センター, 専任技師 2014: 理化学研究所, 放射光科学総合研究センター, 技師 2007 – 2008: 独立行政法人理化学研究所, 研究技術開発室, 協力研究員
Review Section/Research Field	Principal Investigator Basic Section 43020:Structural biochemistry-related Except Principal Investigator Living organism molecular science / Biophysics
Keywords	Principal Investigator タンパク質結晶構造解析 / 結晶学 / 機械学習 / 自動測定 / 放射光構造生物学 / 蛋白質 / 高分解能 / 結晶構造解析 / タンパク質 / 自動データ収集 … More Except Principal Investigator … More ビセリンビオライドA / 標的生体分子探索 / ビセブロモアミド / クラハイン / 小胞体ストレス / トムルリン / 腫瘍細胞増殖阻害 / 結晶構造 / 作用機構 / 化学合成 / 生物活性物質 / アポトーシス / 全合成 / 構造決定 / リポペプチド / ビセリングビアサイド / 海洋シアノバクテリア / 構造機能相関 / α-ヘリックス / 膜融合 / 受精 / 機能 / 動態 / 核酸の構造 / タンパク質 Less

Development of an Automated Diffraction Data Collection System with Artificial IntelligencePrincipal Investigator
- Principal Investigator
  
  Hirata Kunio
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  Institute of Physical and Chemical Research
Bioactive substances from marine cyanobacteria
- Principal Investigator
  
  SUENAGA Kiyotake
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  Keio University
Molecular analysis of sperm-egg fusion as a model system of cell-cell fusion
- Principal Investigator
  
  HAGIHARA Yoshihisa
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biophysics
- Research Institution
  National Institute of Advanced Industrial Science and Technology

All 2025 2024 2023 2022 2007

All Journal Article Presentation

[Journal Article] Useful experimental aspects of small-wedge synchrotron crystallography for accurate structure analysis of protein molecules2025
- Author(s)
  Hirata Kunio
- Journal Title
  
  Acta Crystallographica Section D Structural Biology
  
  Volume: 81 Issue: 1 Pages: 22-37
- DOI
  10.1107/s2059798324011987
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06107
[Journal Article] Elucidating polymorphs of crystal structures by intensity-based hierarchical clustering analysis of multiple diffraction data sets2023
- Author(s)
  Matsuura Hiroaki、Sakai Naoki、Toma-Fukai Sachiko、Muraki Norifumi、Hayama Koki、Kamikubo Hironari、Aono Shigetoshi、Kawano Yoshiaki、Yamamoto Masaki、Hirata Kunio
- Journal Title
  
  Acta Crystallographica Section D Structural Biology
  
  Volume: 79 Issue: 10 Pages: 909-924
- DOI
  10.1107/s2059798323007039
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06031, KAKENHI-PROJECT-22K06107, KAKENHI-PROJECT-23K05670, KAKENHI-PLANNED-19H05783, KAKENHI-PLANNED-19H05762
[Journal Article] Engineering of an in-cell protein crystal for fastening a metastable conformation of a target miniprotein2023
- Author(s)
  Mariko Kojima, Satoshi Abe, Tadaomi Furuta, Duy Phuoc Tran, Kunio Hirata, Keitaro Yamashita, Yuki Hishikawa, Akio Kitao, Takafumi Ueno
- Journal Title
  
  Biomaterial Science
  
  Volume: 11 Issue: 4 Pages: 1350-1357
- DOI
  10.1039/d2bm01759h
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21H05510, KAKENHI-PROJECT-22H00347, KAKENHI-PROJECT-19H03191, KAKENHI-PLANNED-18H05421, KAKENHI-PUBLICLY-22H04745, KAKENHI-PROJECT-22K06107
[Journal Article] Constrained catecholamines gain β2AR selectivity through allosteric effects on pocket dynamics2023
- Author(s)
  Xu Xinyu、Shonberg Jeremy、Kaindl Jonas、Clark Mary J.、Strobel Anne、Maul Luis、Mayer Daniel、Hubner Harald、Hirata Kunio、Venkatakrishnan A. J.、Dror Ron O.、Kobilka Brian K.、Sunahara Roger K.、Liu Xiangyu、Gmeiner Peter
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1
- DOI
  10.1038/s41467-023-37808-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06107
[Journal Article] Mechanistic insights into intramembrane proteolysis by E. coli site-2 protease homolog RseP2022
- Author(s)
  Imaizumi Yuki、Hirata Kunio、Nogi Terukazu et al.
- Journal Title
  
  Science Advances
  
  Volume: 8 Issue: 34
- DOI
  10.1126/sciadv.abp9011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06107, KAKENHI-PROJECT-22K06142, KAKENHI-PROJECT-21K19236, KAKENHI-PROJECT-21J15841, KAKENHI-PROJECT-19K06562, KAKENHI-PROJECT-19H03170, KAKENHI-PLANNED-19H05774, KAKENHI-PROJECT-23K23825, KAKENHI-PROJECT-23K23835
[Presentation] Small Wedge Synchrotron Crystallography datasets of Polyhedral protein2024
- Author(s)
  平田邦生
- Organizer
  ”Diffraction Methods in Structural Biology"
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06107
[Presentation] 自動測定システムZOOの歩んだ道・歩む道2024
- Author(s)
  平田邦生、河野能顕、上野剛、松浦滉明、坂井直樹、馬場清喜、水野伸宏、仲村勇樹、村上博則、長谷川和也、熊坂崇、山本雅貴
- Organizer
  日本放射光学会年会
- Data Source
  KAKENHI-PROJECT-22K06107
[Presentation] Automatic data collection at SPring-8/Japan2024
- Author(s)
  平田邦生
- Organizer
  MXCuBE-ISPyB Joint meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06107
[Presentation] SPring-8自動測定システムZOOの歩んだ８年間2023
- Author(s)
  Kunio Hirata、Hiroaki Matsuura, Yoshiaki Kawano, Naoki Sakai, Kazuya Hasegawa, Takashi Kumasaka, Masaki Yamamoto
- Organizer
  日本結晶学会年会
- Data Source
  KAKENHI-PROJECT-22K06107
[Presentation] Current status of serial crystallography at SPring-8 MX beamlines2023
- Author(s)
  Kunio Hirata、Hiroaki Matsuura, Yoshiaki Kawano, Naoki Sakai, Kazuya Hasegawa, Takashi Kumasaka, Masaki Yamamoto
- Organizer
  The 74th ACA Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06107
[Presentation] Is there a best method in data collection? ~an Asian Perspective~2022
- Author(s)
  Kunio Hirata
- Organizer
  Gordon Conference (Diffraction Methods in Structural Biology)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06107
[Presentation] 受精膜融合もαヘリックスを使うのかIzumoフラグメントの構造機能解析2007
- Author(s)
  萩原義久、井上直和、平田邦生、浜田大三、上久保裕生、片岡幹雄、山本雅貴、岡部勝
- Organizer
  第30回日本分子生物学会・第80回日本生化学会合同年会
- Place of Presentation
  横浜
- Year and Date
  2007-12-12
- Data Source
  KAKENHI-PROJECT-19570159
[Presentation] 受精膜融合もαヘリックスを使うのか?Izumo フラグメントの構造機能解析2007
- Author(s)
  萩原義久, 井上直和, 平田邦生, 浜田大三, 上久保裕生,片岡幹雄, 山本雅貴, 岡部勝
- Organizer
  第30回日本分子生物学会・第80回日本生化学会合同年会
- Place of Presentation
  横浜
- Year and Date
  2007-12-12
- Data Source
  KAKENHI-PROJECT-19570159

1. INOUE Naokazu (50379096)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
2. YAMAMOTO Masaki (60241254)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
3. HAGIHARA Yoshihisa (50357761)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. MINE Shouhei (70415751)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. SUENAGA Kiyotake (60273215)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. TERUYA Toshiaki (90375428)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. OHNO Osamu (20436992)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. MIYAMOTO Kenji (60360111)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 藤間祥子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 北尾彰朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hirata Kunio 平田 邦生

HIRATA Kunio 平田 邦生

Research Projects

Research Products

Co-Researchers

Development of an Automated Diffraction Data Collection System with Artificial IntelligencePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Bioactive substances from marine cyanobacteria

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular analysis of sperm-egg fusion as a model system of cell-cell fusion

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Useful experimental aspects of small-wedge synchrotron crystallography for accurate structure analysis of protein molecules2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Elucidating polymorphs of crystal structures by intensity-based hierarchical clustering analysis of multiple diffraction data sets2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Engineering of an in-cell protein crystal for fastening a metastable conformation of a target miniprotein2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Constrained catecholamines gain β2AR selectivity through allosteric effects on pocket dynamics2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mechanistic insights into intramembrane proteolysis by E. coli site-2 protease homolog RseP2022

Author(s)

Journal Title

DOI

Data Source

[Presentation] Small Wedge Synchrotron Crystallography datasets of Polyhedral protein2024

Author(s)

Organizer

Data Source

[Presentation] 自動測定システムZOOの歩んだ道・歩む道2024

Author(s)

Organizer

Data Source

[Presentation] Automatic data collection at SPring-8/Japan2024

Author(s)

Organizer

Data Source

[Presentation] SPring-8自動測定システムZOOの歩んだ８年間2023

Author(s)

Organizer

Data Source

[Presentation] Current status of serial crystallography at SPring-8 MX beamlines2023

Author(s)

Organizer

Data Source

[Presentation] Is there a best method in data collection? ~an Asian Perspective~2022

Author(s)

Organizer

Data Source

[Presentation] 受精膜融合もαヘリックスを使うのかIzumoフラグメントの構造機能解析2007

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 受精膜融合もαヘリックスを使うのか?Izumo フラグメントの構造機能解析2007

Author(s)

Hirata Kunio 平田邦生

HIRATA Kunio 平田邦生