Okugawa Syu 奥川周

… Alternative Names

OKUGAW SHU 奥川周

OKUGAWA Shu 奥川周

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Researcher Number	20376461
Other IDs	https://orcid.org/0000-0003-3455-8291
Affiliation (Current)	2025: 東京大学, 医学部附属病院, 准教授
Affiliation (based on the past Project Information) *help	2019 – 2021: 東京大学, 医学部附属病院, 准教授 2005 – 2006: 東京大学, 医学部附属病院, 助手
Review Section/Research Field	Principal Investigator Basic Section 54030:Infectious disease medicine-related / 膠原病・アレルギー・感染症内科学 Except Principal Investigator 膠原病・アレルギー・感染症内科学
Keywords	Principal Investigator クロストリジウム / 機能 / 分子疫学 / quorum sensing / Clostridioides difficile / CRISPR-Cas9 / agr遺伝子 / accessory gene regulator / agr / クオラムセンシング … More / C. difficile / Zap70 / グラム陰性桿菌 / 自然免疫 / SOCS-1 / Jurkat / TLR5 / フラジェリン / TLR / T細胞受容体 / T細胞 … More Except Principal Investigator TLR4 / LPS / TLR / LL motif / cellular localization / innate immunity / トラフィック / 細胞内輸送 / LLモチーフ / 細胞内分布 / 自然免疫 Less

Molecular epidemiology and mechanism of quorum sensing system in C. difficilePrincipal Investigator
- Principal Investigator
  
  OKUGAW SHU
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  The University of Tokyo
グラム陰性桿菌の鞭毛蛋白フラジェリンを用いた宿主免疫からの逃避機序の解析Principal Investigator
- Principal Investigator
  
  奥川周
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  The University of Tokyo
Molecular mechanism of intracellular trafficking of TLR4
- Principal Investigator
  
  OTA Yasuo
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  The University of Tokyo

All 2022 2021 2020 2019 2007 2006 Other

All Journal Article Presentation Other

[Journal Article] Protothecosis in the mucosa of the pharynx mimicking pharyngeal cancer in an immunocompetent individual: a case report2022
- Author(s)
  Yamashita Marie、Ikeda Mahoko、Kato Ito、Ohama Yuki、Ando Mizuo、Ikemura Masako、Jubishi Daisuke、Kanno Yoshiaki、Okamoto Koh、Umeyama Takashi、Nakamura Shigeki、Miyazaki Yoshitsugu、Okugawa Shu、Moriya Kyoji
- Journal Title
  
  Annals of Clinical Microbiology and Antimicrobials
  
  Volume: 21 Issue: 1 Pages: 5-5
- DOI
  10.1186/s12941-022-00495-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08949, KAKENHI-PROJECT-20K08834
[Journal Article] Urine sediment findings were milder in patients with COVID-19-associated renal injuries than in those with non-COVID-19-associated renal injuries2022
- Author(s)
  Morita Yoshifumi、Kurano Makoto、Jubishi Daisuke、Ikeda Mahoko、Okamoto Koh、Tanaka Masami、Harada Sohei、Okugawa Shu、Moriya Kyoji、Yatomi Yutaka
- Journal Title
  
  International Journal of Infectious Diseases
  
  Volume: 117 Pages: 302-311
- DOI
  10.1016/j.ijid.2022.02.024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08949
[Journal Article] Incidence and Risk Factors for Inappropriate Use of Non-Culture-Based Fungal Assays: Implication for Diagnostic Stewardship2021
- Author(s)
  Ito Hiroshi、Okamoto Koh、Yamamoto Shinya、Yamashita Marie、Kanno Yoshiaki、Jubishi Daisuke、Ikeda Mahoko、Harada Sohei、Okugawa Shu、Moriya Kyoji
- Journal Title
  
  Open Forum Infectious Diseases
  
  Volume: 9 Issue: 1
- DOI
  10.1093/ofid/ofab601
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08949
[Journal Article] First Reported Human Case of Spondylodiscitis by <i>Staphylococcus condimenti</i>: A Case Report and Literature Review2021
- Author(s)
  Kobayashi T, Nakajima K, Oshima Y, Ikeda M, Kitaura S, Ikeuchi K, Okamoto K, Okada Y, Ohama Y, Higurashi Y, Okugawa S, Moriya K.
- Journal Title
  
  Intern. Med.
  
  Volume: 60 Issue: 4 Pages: 635-637
- DOI
  10.2169/internalmedicine.5180-20
- NAID
  130007986378
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2021-02-15
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08949
[Journal Article] Clot waveform of APTT has abnormal patterns in subjects with COVID-192021
- Author(s)
  Shimura Takuya、Kurano Makoto、Kanno Yoshiaki、Ikeda Mahoko、Okamoto Koh、Jubishi Daisuke、Harada Sohei、Okugawa Shu、Moriya Kyoji、Yatomi Yutaka
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 5190-5190
- DOI
  10.1038/s41598-021-84776-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08949
[Journal Article] Chronic Disseminated Gonococcal Infection in a Japanese Man with Novel C5 Gene Mutation.2021
- Author(s)
  Ikeuchi, K., Okamoto, K., Inoue, N., Okugawa, S., Moriya, K.
- Journal Title
  
  J Clin Immunol
  
  Volume: 41 Issue: 3 Pages: 691-693
- DOI
  10.1007/s10875-020-00959-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03529, KAKENHI-PROJECT-19K08949
[Journal Article] Plesiomonas shigelloides Septic Shock Following Ingestion of Dojo Nabe (Loach Hotpot)2021
- Author(s)
  Shinohara Takayuki、Okamoto Koh、Koyano Saho、Otani Amato、Yamashita Marie、Wakimoto Yuji、Jubishi Daisuke、Hashimoto Hideki、Ikeda Mahoko、Harada Sohei、Okugawa Shu、Moriya Kyoji
- Journal Title
  
  Open Forum Infectious Diseases
  
  Volume: 8 Issue: 8
- DOI
  10.1093/ofid/ofab401
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08949
[Journal Article] First human case of catheter-related blood stream infection caused by Staphylococcus schleiferi subspecies coagulans: a case report and literature review2021
- Author(s)
  Kobayashi Tatsuya、Ikeda Mahoko、Ohama Yuki、Murono Koji、Ikeuchi Kazuhiko、Kitaura Satoshi、Okamoto Koh、Okugawa Shu、Ishihara Soichiro、Moriya Kyoji
- Journal Title
  
  Annals of Clinical Microbiology and Antimicrobials
  
  Volume: 20 Issue: 1 Pages: 68-68
- DOI
  10.1186/s12941-021-00474-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08949
[Journal Article] The prevalence of the iutA and ibeA genes in Escherichia coli isolates from severe and non-severe patients with bacteremic acute biliary tract infection is significantly different2021
- Author(s)
  Ikeda Mahoko、Kobayashi Tatsuya、Fujimoto Fumie、Okada Yuta、Higurashi Yoshimi、Tatsuno Keita、Okugawa Shu、Moriya Kyoji
- Journal Title
  
  Gut Pathogens
  
  Volume: 13 Issue: 1 Pages: 32-32
- DOI
  10.1186/s13099-021-00429-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08949
[Journal Article] Clinical and Microbiological Characteristics of Recurrent Escherichia coli Bacteremia2021
- Author(s)
  Kobayashi Tatsuya、Ikeda Mahoko、Okada Yuta、Higurashi Yoshimi、Okugawa Shu、Moriya Kyoji
- Journal Title
  
  Microbiology Spectrum
  
  Volume: 9 Issue: 3
- DOI
  10.1128/spectrum.01399-21
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08949
[Journal Article] Poor penetration of cefcapene into aqueous humor after oral administration of cefcapene pivoxil to patients undergoing cataract surgery2020
- Author(s)
  Okamoto Koh、Asano Shotaro、Yamamoto Takehito、Toyono Tetsuya、Yamaguchi Ryo、Okada Yuta、Okugawa Shu、Suzuki Hiroshi、Moriya Kyoji、Aihara Makoto
- Journal Title
  
  Journal of Infection and Chemotherapy
  
  Volume: 26 Issue: 2 Pages: 312-315
- DOI
  10.1016/j.jiac.2019.08.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08949, KAKENHI-PROJECT-17K08437
[Journal Article] Microbiological analysis of infectious lymphocele: Case series and literature review.2020
- Author(s)
  Yamamoto S, Ikeda M, Kanno Y, Okamoto K, Okugawa S, Moriya K.
- Journal Title
  
  J Infect Chemother.
  
  Volume: 27(2) Issue: 2 Pages: 172-178
- DOI
  10.1016/j.jiac.2020.08.021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08949
[Journal Article] Genetic diversity and epidemiology of accessory gene regulator loci in Clostridioides difficile2020
- Author(s)
  Yuta Okada, Shu Okugawa, Mahoko Ikeda, Tatsuya Kobayashi, Ryoichi Saito, Yoshimi Higurashi, Kyoji Moriya
- Journal Title
  
  Access Microbiology
  
  Volume: (2)7 Issue: 7
- DOI
  10.1099/acmi.0.000134
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08949, KAKENHI-PROJECT-20K08818
[Journal Article] 【ウイルス肝炎アップデート】ウイルス性肝炎のトピックス　しばしば見かける肝炎ウイルス以外のウイルス感染症による肝機能障害2020
- Author(s)
  岡田雄大, 奥川周
- Journal Title
  
  診断と治療
  
  Volume: 108 Pages: 253-256
- Data Source
  KAKENHI-PROJECT-19K08949
[Journal Article] Acute Pancreatitis During COVID-19 Pneumonia.2020
- Author(s)
  Shinohara T, Otani A, Yamashita M, Wakimoto Y, Jubishi D, Okamoto K, Kanno Y, Ikeda M, Ishigaki K, Nakai Y, Harada S, Okugawa S, Koike K, Moriya K.
- Journal Title
  
  Pancreas
  
  Volume: 49(10) Issue: 10 Pages: e106-e108
- DOI
  10.1097/mpa.0000000000001695
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08949
[Journal Article] Impact of deoxycholate on Clostridioides difficile growth, toxin production, and sporulation2020
- Author(s)
  Usui Y, Ayibieke A, Kamiichi Y, Okugawa S, Moriya K, Tohda S, Saito R.
- Journal Title
  
  Heliyon
  
  Volume: 6(4) Issue: 4 Pages: e03717-e03717
- DOI
  10.1016/j.heliyon.2020.e03717
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08949
[Journal Article] 感染症の病原体核酸検査の現状と将来展望　細菌感染症診療における遺伝子検査　感染症専門医の立場から2019
- Author(s)
  池田麻穂子, 奥川周, 森屋恭爾
- Journal Title
  
  臨床病理
  
  Volume: 67 Pages: 1179-1185
- Data Source
  KAKENHI-PROJECT-19K08949
[Journal Article] Fusobacterium necrophorum septic pelvic thrombophlebitis after intrauterine device insertion2019
- Author(s)
  Yamamoto Shinya、Okamoto Koh、Okugawa Shu、Moriya Kyoji
- Journal Title
  
  International Journal of Gynecology & Obstetrics
  
  Volume: 145 Issue: 1 Pages: 122-123
- DOI
  10.1002/ijgo.12760
- Data Source
  KAKENHI-PROJECT-19K08949
[Journal Article] Relationship between initial dose of micafungin and its efficacy in patients with candidemia.2007
- Author(s)
  Ota Y, Tatsuno K, Okugawa S, Yanagimoto S, Kitazawa K, Fukushima A, Tsukada K, Koike K.
- Journal Title
  
  J Infect Chem. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591034
[Journal Article] Relationship between initiad dose of micafungin and its efficacy in patients with candidemia.2007
- Author(s)
  Ota Y, Tatsuno K, Okugawa S, Yanagimoto S, Uitazawa K
- Journal Title
  
  J Infect Chem (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591034
[Journal Article] A case of invasive central nervous system aspergillosis treated with micafungin with monitoring of micafungin concentrations in the cerebrospinal fluid2007
- Author(s)
  奥川, 周
- Journal Title
  
  Scand. J. Inf. Dis. (印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591034
[Journal Article] A case of invasive central nervous sytem aspergillosis treated with micafungin with monitoring of micafungin concentrations in the cerebrospinal fluid2007
- Author(s)
  奥川周
- Journal Title
  
  Scand.J.Inf.Dis. (印刷中)
- Data Source
  KAKENHI-PROJECT-17591034
[Journal Article] A case of invasive central nervous system aspergillosis treated with micafungin with monitoring of micafungin concentrations in the cerebrosppinal fluid.2007
- Author(s)
  Okugawa, S., Ota, Y., Tatsun, K., Tsukada, K., Kishino, S., Koike, K.
- Journal Title
  
  Scand.J.Inf.Dis. (Published on line)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591034
[Journal Article] Biphasic regulation of levofloxacin on lipopolysaccharide-induced IL-1β production.2007
- Author(s)
  Kitazawa T, Nakayama K, Okugawa S, Koike K, Shibasaki Y, Ota Y.
- Journal Title
  
  Life Sci 80
  
  Pages: 1572-1577
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591034
[Journal Article] A case of invasive central nervous system aspergillosis treated with micafungin with monitoring of micafungin concentrations in the cerebrospinal fluid2007
- Author(s)
  奥川, 周
- Journal Title
  
  Scand.J.Inf.Dis. (印刷中)
- Data Source
  KAKENHI-PROJECT-17790669
[Journal Article] Dengue Hemorrhagic Shock and Disseminated Candidiasis.2007
- Author(s)
  Suzuki S, Kitazawa T, Ota Y, Okugawa S, Tsukada K, Nukui Y, Hatakeyama S, Yamaguchi D, Matsuse S, Ishii T, Matsubara T, Yamauchi C, Ota S, Yahagi N, Fukayama M, Koike K.
- Journal Title
  
  Intern Med (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591034
[Journal Article] Bacterial flagellin inhibits T cell receptor-mediated activation of T cells by inducing SOCS-12006
- Author(s)
  奥川, 周
- Journal Title
  
  Cell Microbiol. 8
  
  Pages: 1571-1580
- Data Source
  KAKENHI-PROJECT-17790669
[Journal Article] Bacterial flagellin inhibits T cell receptor-mediated activation of T cells by inducing SOCS-12006
- Author(s)
  奥川周
- Journal Title
  
  Cell Microbiol. 8
  
  Pages: 1571-80
- Data Source
  KAKENHI-PROJECT-17591034
[Journal Article] Bacterial flagellin inhibits T cell receptor-mediated activation of T cells by inducing SOCS-12006
- Author(s)
  奥川, 周
- Journal Title
  
  Cell Microbiol. 8
  
  Pages: 1571-1580
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591034
[Journal Article] Expression and function of toll-kike receptors in human basophils.2006
- Author(s)
  Komiya, A., Nagase, H., Okugawa, S., Ota, Y., Suzukawa, M., Kawakami, A., Sekiya, T., Matsushima, K., Ohta, K., Hirai, K., Yamamoto, K., Yamaguchi, M.
- Journal Title
  
  Int Arch Allergy Immunol. 140 Suppl 1
  
  Pages: 23-27
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591034
[Journal Article] Bacterial flagellin inhibits T cell receptor-mediated activation of T cells by inducing SOCS-1.2006
- Author(s)
  Okugawa, S., Tsukasa, K., Kitazawa, T., Koike, K., Kimura, S., Nagase, H., Hirai, K., Ota, Y.
- Journal Title
  
  Cell Microbiol. 8
  
  Pages: 1571-1580
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591034
[Journal Article] Bacterial flagellin inhibits T cell receptor-mediated activation of T cells by inducing SOCS-1
- Author(s)
  Shu Okugawa, et al.
- Journal Title
  
  Cellular Microbiology (印刷中)
- Data Source
  KAKENHI-PROJECT-17591034
[Journal Article] Bacterial flagellin inhibits T cell receptor-mediated activation of T cells by inducing SOCS-1
- Author(s)
  Shu Okugawa, et al.
- Journal Title
  
  Cellular Microbiology (印刷中)
- Data Source
  KAKENHI-PROJECT-17790669
[Presentation] Clinical and Microbiological Differences in Recurrent Escherichia coli Bacteremia Is Dependent on the Bacteria Genetic Identity2021
- Author(s)
  T. Kobayashi, M. Ikeda, Y. Okada, Y. Higurashi, S. Okugawa, K. Moriya
- Organizer
  WORLD MICROBE FORUM 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08949
[Presentation] 繰り返す大腸菌菌血症における遺伝的相同性の有無による臨床的・微生物学的特徴の検討2021
- Author(s)
  小林竜也、池田麻穂子、岡田雄大、日暮芳己、奥川周、森屋恭爾
- Organizer
  第70回日本感染症学会東日本地方会学術集会・第68回日本化学療法学会東日本支部総会合同学会
- Data Source
  KAKENHI-PROJECT-19K08949
[Presentation] Genetic Diversity and Epidemiology of Accessory Gene Regulator Loci in the Clinical Isolates of Clostridioides Difficile2020
- Author(s)
  Yuta Okada, Shu Okugawa, Mahoko Ikeda, Tatsuya Kobayashi, Ryoichi Saito, Yoshimi Higurashi, Kyoji Moriya
- Organizer
  ASM microbe　2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08949
[Presentation] リンパ嚢胞感染の微生物学的検討：当院での8年間における症例検討とliterature review2019
- Author(s)
  山本真也、池田麻穂子、菅野芳明、岡本耕、奥川周、森屋恭爾
- Organizer
  第６８回日本感染症学会東日本地方会学術集会
- Data Source
  KAKENHI-PROJECT-19K08949
[Presentation] ．生焼けのサバ摂取後に発症した Raoultella ornithi nolytica 菌血症2019
- Author(s)
  伊東完，岡本耕，山本真也山下麻梨絵，菅野芳明，池田麻穂子奥川周，森屋恭爾
- Organizer
  第６８回日本感染症学会東日本地方会学術集会
- Data Source
  KAKENHI-PROJECT-19K08949
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1. OTA Yasuo (80292936)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
2. 井上徳光

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Okugawa Syu 奥川 周

OKUGAW SHU 奥川 周

OKUGAWA Shu 奥川 周

Research Projects

Research Products

Co-Researchers

Molecular epidemiology and mechanism of quorum sensing system in C. difficilePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

グラム陰性桿菌の鞭毛蛋白フラジェリンを用いた宿主免疫からの逃避機序の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanism of intracellular trafficking of TLR4

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Protothecosis in the mucosa of the pharynx mimicking pharyngeal cancer in an immunocompetent individual: a case report2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Urine sediment findings were milder in patients with COVID-19-associated renal injuries than in those with non-COVID-19-associated renal injuries2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Incidence and Risk Factors for Inappropriate Use of Non-Culture-Based Fungal Assays: Implication for Diagnostic Stewardship2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] First Reported Human Case of Spondylodiscitis by <i>Staphylococcus condimenti</i>: A Case Report and Literature Review2021

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] Clot waveform of APTT has abnormal patterns in subjects with COVID-192021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Chronic Disseminated Gonococcal Infection in a Japanese Man with Novel C5 Gene Mutation.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Plesiomonas shigelloides Septic Shock Following Ingestion of Dojo Nabe (Loach Hotpot)2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] First human case of catheter-related blood stream infection caused by Staphylococcus schleiferi subspecies coagulans: a case report and literature review2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The prevalence of the iutA and ibeA genes in Escherichia coli isolates from severe and non-severe patients with bacteremic acute biliary tract infection is significantly different2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Clinical and Microbiological Characteristics of Recurrent Escherichia coli Bacteremia2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Poor penetration of cefcapene into aqueous humor after oral administration of cefcapene pivoxil to patients undergoing cataract surgery2020

Author(s)

Okugawa Syu 奥川周

OKUGAW SHU 奥川周

OKUGAWA Shu 奥川周

[Journal Article] 【ウイルス肝炎アップデート】ウイルス性肝炎のトピックス　しばしば見かける肝炎ウイルス以外のウイルス感染症による肝機能障害2020

[Journal Article] 感染症の病原体核酸検査の現状と将来展望　細菌感染症診療における遺伝子検査　感染症専門医の立場から2019