TAKENAKA Katsuya 竹中克也

… Alternative Names

竹中克也タケナカカツヤ

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Researcher Number	20378706
Other IDs
Affiliation (based on the past Project Information) *help	2016 – 2018: 地方独立行政法人神奈川県立病院機構神奈川県立がんセンター(臨床研究所), その他部局等, 技師・研究員 2015: 地方独立行政法人神奈川県立病院機構神奈川県立がんセンター(臨床研究所), その他部局等, 研究員 2009 – 2014: Tokyo Medical and Dental University, 難治疾患研究所, 助教 2005: 京都大学, 医学研究科, 21世紀COE特任助手
Review Section/Research Field	Principal Investigator Pathological medical chemistry / Tumor biology Except Principal Investigator General medical chemistry / Tumor biology
Keywords	Principal Investigator タンパク質間相互作用 / 画像認識 / 中心体 / U2OS / DR-GFP / DNA損傷修復 / 乳癌 / BRCA2 / 遺伝子破壊 / 低酸素 … More / 分子内責任部位 / 中心体複製 / BRCA / 質量分析 / ROCK2 / nucleophonsmin / 分子腫瘍学 … More Except Principal Investigator DNA polymerase / Fbh1 / Ubc13 / Rad18 / Gene targeting / DT40 cell / Targeted integration / Homologous Recombination / 老化 / 放射線 / 細胞・組織 / 癌 / 遺伝学 / 遺伝子破壊 / DT40細胞 / 標的組換え / 相同DNA組換え / 抗がん剤 / BRCA1/BRCA2 / がん抑制遺伝子 / BRCA1/2遺伝子 / 化合物ライブラリー / 合成致死 / BRCA2 / 乳がん Less

Molecular regions of BRCA proteins responsible for cancer suppressionPrincipal Investigator
- Principal Investigator
  
  Takenaka Katsuya
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  Kanagawa Cancer Center Research Institute
Functional analysis of BRCA genes and searching for molecular partner for synthetic lethality.
- Principal Investigator
  
  MIKI Yoshio
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor biology
- Research Institution
  Tokyo Medical and Dental University
Function of novel BRCA2-associating proteins in centrosomal regulation and DNA repairPrincipal Investigator
- Principal Investigator
  
  TAKENAKA Katsuya
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tokyo Medical and Dental University
Screening and analyses of novel BRCA1/2-associated proteinsPrincipal Investigator
- Principal Investigator
  
  TAKENAKA Katsuya
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tokyo Medical and Dental University
Analysis of Homologous DNA Recombination using the chicken DT40 B cell line
- Principal Investigator
  
  TAKEDA Shunichi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Kyoto University

All 2019 2018 2014 2013 2012 2010 2009 2006

All Journal Article Presentation

[Journal Article] Cholesterol Starvation and Hypoxia Activate the FVII Gene via the SREBP1-GILZ Pathway in Ovarian Cancer Cells to Produce Procoagulant Microvesicles2019
- Author(s)
  Koizume S, Takahashi T, Yoshihara M, Nakamura Y, Ruf W, Takenaka K, Miyagi E, and Miyagi Y.
- Journal Title
  
  Thromb. Haemost.
  
  Volume: 印刷中 Issue: 07 Pages: 1058-1071
- DOI
  10.1055/s-0039-1687876
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08346, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-15K06833
[Journal Article] BRCA2 phosphorylated by PLK1 moves to the midbody to regulate cytokinesis mediated by nonmuscle myosin IIC.2014
- Author(s)
  Takaoka, Saito, Takenaka, Miki, and Nakanishi
- Journal Title
  
  Cancer Research
  
  Volume: 74 Issue: 5 Pages: 1518-1528
- DOI
  10.1158/0008-5472.can-13-0504
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590355, KAKENHI-PROJECT-24300328, KAKENHI-PUBLICLY-25134709, KAKENHI-PROJECT-25640061
[Journal Article] Mutations in UVSSA cause UV-sensitive syndrome and impair RNA polymerase IIo processing in transcription-coupled nucleotide-excision repair2012
- Author(s)
  Nakazawa Y, Sasaki K, Mitsutake N, Yamashita S, Ogi T, et al
- Journal Title
  
  Nat Genet
  
  Volume: 44(5) Issue: 5 Pages: 586-92
- DOI
  10.1038/ng.2229
- NAID
  120006985586
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390189, KAKENHI-PROJECT-22710056, KAKENHI-PROJECT-22791204, KAKENHI-PROJECT-23510065, KAKENHI-PROJECT-23590355, KAKENHI-PROJECT-24300328, KAKENHI-PROJECT-24390199, KAKENHI-PROJECT-24590403, KAKENHI-PROJECT-24659533, KAKENHI-PROJECT-24681008, KAKENHI-PROJECT-24790321
[Journal Article] Three DNA polymerases, recruited by different mechanisms, carry out NER repair synthesis in human cells.2010
- Author(s)
  Tomoo Ogi, Siripan Limsirichaikul^+, Ren M.Overmeer^+, Marcel Volker^+, Katsuya Takenaka^+, Ross Cloney^+, Yuka Nakazawa^+, Atsuko Niimi, Yoshio Miki, Nicolaas G.Jaspers, Leon H.F.Mullenders, Shunichi Yamashita, Maria I.Fousteri, Alan R.Lehmann.
- Journal Title
  
  Molecular Cell 37
  
  Pages: 714-727
- NAID
  120006984627
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790311
[Journal Article] BRCA2 and nucleophosmin coregulate centrosome amplification and form a complex with ROCK2.2010
- Author(s)
  Hui-Feng Wang, Katsuya Takenaka, Akira Nakanishi, Yoshio Miki.
- Journal Title
  
  Cancer Research 71
  
  Pages: 68-77
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790311
[Journal Article] PTIP promotes DNA double-strand break repair through homologous recombination.2010
- Author(s)
  Xin Wang, Katsuya Takenaka, Shunichi Takeda.
- Journal Title
  
  Genes to Cells 15
  
  Pages: 243-254
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790311
[Journal Article] Introduction and characterization of a polymerase-dead point mutation into the POLK gene in vertebrates.2009
- Author(s)
  Katsuya, Takenaka, Yoshio Miki.
- Journal Title
  
  FEBS Letters 583
  
  Pages: 661-664
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790311
[Journal Article] Genetic evidence for single-strand lesions initiating Nbs1-dependent homologous recombination in diversification of Ig V in chicken B lymphocytes.2009
- Author(s)
  Makoto Nakahara, Eiichiro Sonoda, Kuniharu Nojima, Julian E.Sale, Katsuya Takenaka, Koji Kikuchi, Yoshihito Taniguchi, Kyoko Nakamura, Yoshiki Sumitomo, Ronan T.Bree, Noel F.Lowndes, Shunichi Takeda.
- Journal Title
  
  PLoS Genetics 5
  
  Pages: 1000356-1000356
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790311
[Journal Article] Introduction and characterization of a polymerase-dead point mutation into the POLK gene in vertebrates2009
- Author(s)
  Takenaka
- Journal Title
  
  FEBS Letters 583
  
  Pages: 661-664
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790311
[Journal Article] Involvement of vertebrate Polkappa in translesion DNA synthesis across DNA monoalkylation damage.2006
- Author(s)
  Takenaka K, Ogi T, Okada T, Sonoda E, Guo C, Friedberg EC, Takeda S.
- Journal Title
  
  J Biol Chem. 281
  
  Pages: 2000-2004
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390076
[Journal Article] Involvement of vertebrate Polkappa in translesion DNA synthesis across DNA monoalkylation damage.2006
- Author(s)
  Takenaka T, Ogi T, Okada T, Sonoda E, Guo C, Friedberg EC, Takeda S
- Journal Title
  
  Journal of Biological Chemistry 281
  
  Pages: 2000-2004
- Data Source
  KAKENHI-PROJECT-17390076
[Journal Article] Involvement of vertebrate Polkappa in translesion DNA synthesis across DNA monoalkylation damage.2006
- Author(s)
  Takenaka T, Ogi T, Okada T, Sonoda E, Guo C, Friedberg EC, Takeda S
- Journal Title
  
  J Biol Chem 281
  
  Pages: 2000-2004
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390076
[Presentation] 低酸素で発現誘導されるATP-graspスーパーファミリー酵素(Expression of an ATP-grasp superfamily enzyme under hypoxia)2018
- Author(s)
  竹中克也, 小森由香子, 中村圭靖, 小井詰史朗, 宮城洋平
- Organizer
  第77回日本癌学会総会
- Data Source
  KAKENHI-PROJECT-15K06833
[Presentation] 異所性CD69発現は卵巣明細胞がん細胞の腹腔内生存に重要である(Ectopic synthesis of CD69 is important for intra-peritoneal survival of ovarian clear cell carcinoma cells)2018
- Author(s)
  小井詰史朗, 中村圭靖, 吉原光代, 竹中克也, 宮城悦子, 宮城洋平
- Organizer
  第77回日本癌学会総会
- Data Source
  KAKENHI-PROJECT-15K06833
[Presentation] Function of BRCA2 and its associating proteins in centrosomal regulation2013
- Author(s)
  Teshirogi, Miki, and Takenaka
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23590355
[Presentation] 中心体複製制御における乳癌原因遺伝子BRCA2とその結合分子の役割2013
- Author(s)
  手代木翔太, 三木義男, 竹中克也
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590355
[Presentation] 乳癌原因遺伝子BRCA2 新規結合分子の探索と相互作用が発癌に果たす分子機構の解明2012
- Author(s)
  竹中克也
- Organizer
  難治疾患研究所研究発表会(招待講演)
- Place of Presentation
  東京医科歯科大学
- Data Source
  KAKENHI-PROJECT-23590355
[Presentation] Three DNA polymerases, recruited by different mechanisms, carry out NER repair synthesis in human cells.2010
- Author(s)
  Tomoo Ogi, Siripan Limsirichaikul, Ren M. Overmeer, Marcel Volker, Katsuya Takenaka, Ross Cloney, Yuka Nakazawa, Atsuko Niimi, Yoshio Miki, Nicolaas G., Jaspers, Leon H.F., Mullenders, Shunichi Yamashita, Maria I., Fousteri, Alan R.Lehmann.
- Organizer
  International Conference on Radiation and Cancer Biology at Nagasaki 2010
- Place of Presentation
  Nagasaki
- Data Source
  KAKENHI-PROJECT-21790311
[Presentation] BRCA2 and nucleophosmin coregulate centrosome amplification and form a complex with ROCK2.2010
- Author(s)
  Hui-Feng Wang, Katsuya Takenaka, Akira Nakanishi, Yoshio Miki.
- Organizer
  The Sixth International Symposium on Hormononmonnium on Hormonal Oncogenesis
- Place of Presentation
  Urayasu
- Data Source
  KAKENHI-PROJECT-21790311
[Presentation] BRCA2 and nucleophosmin coregulate centrosome amplification and form a complex with ROCK22010
- Author(s)
  Takenaka
- Organizer
  BMB2010
- Place of Presentation
  Kobe
- Data Source
  KAKENHI-PROJECT-21790311
[Presentation] Introduction and characterization of a polymerase-dead point mutation into the POLK gene in vertebrates.2010
- Author(s)
  Katsuya Takenaka, Yoshio Miki.
- Organizer
  International Conference on Radiation and Cancer Biology at Nagasaki 2010
- Place of Presentation
  Nagasaki
- Data Source
  KAKENHI-PROJECT-21790311
[Presentation] BRCA2 and nucleophosmin coregulate centrosome amplification and form a complex with2010
- Author(s)
  Katsuya Takenaka, Hui-Feng Wang, Akira Nakanishi, Yoshio Miki.
- Organizer
  ROCK2.BMB2010
- Place of Presentation
  Kobe
- Data Source
  KAKENHI-PROJECT-21790311
[Presentation] Introduction and characterization of a polymerase-dead point mutation into the POLK gene in vertebrates2010
- Author(s)
  竹中克也
- Organizer
  International Conference on Radiation and Cancer Biology at Nagasaki 2010
- Place of Presentation
  Nagasaki
- Data Source
  KAKENHI-PROJECT-21790311
[Presentation] ゲノム上点変異導入によるPol_K活性中心変異株の作製と解析2009
- Author(s)
  竹中克也
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21790311
[Presentation] Three DNA polymerases, recruited by different mechanisms, carry out NER repair synthesis in human cells.2009
- Author(s)
  Tomoo Ogi, Limsirichaikul Siripan, Marcel Volker, Rene Overmeer, Katsuya Takenaka, Ross Cloney, Yuka Nakazawa, Atsuko Niimi, Yoshio Miki, Nicolaas Jaspers, Leon Mullenders, Maria Fousteri, Shunichi Yamashita, Alan Lehmann.
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21790311
[Presentation] ゲノム上点変異導入によるPolκ活性中心変異株の作製と解析2009
- Author(s)
  竹中克也, 三木義男
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21790311
[Presentation] Introduction and characterization of a polymerase-dead point mutation into the POLK gene in vertebrates.2009
- Author(s)
  Katsuya Takenaka, Yoshio Miki.
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21790311
[Presentation] Introduction and characterization of a polymerase-dead point mutation into the POLK gene in vertebrates2009
- Author(s)
  竹中克也
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21790311

1. OGI Tomoo (80508317)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
2. MIKI Yoshio (10281594)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. NAKANISHI Akira (50321790)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. TAKEDA Shunichi (60188191)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. KOIZUME Shiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 光武範吏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 山下俊一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 宮城洋平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TAKENAKA Katsuya 竹中 克也

竹中 克也 タケナカ カツヤ

Research Projects

Research Products

Co-Researchers

Molecular regions of BRCA proteins responsible for cancer suppressionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional analysis of BRCA genes and searching for molecular partner for synthetic lethality.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Function of novel BRCA2-associating proteins in centrosomal regulation and DNA repairPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Screening and analyses of novel BRCA1/2-associated proteinsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of Homologous DNA Recombination using the chicken DT40 B cell line

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Cholesterol Starvation and Hypoxia Activate the FVII Gene via the SREBP1-GILZ Pathway in Ovarian Cancer Cells to Produce Procoagulant Microvesicles2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] BRCA2 phosphorylated by PLK1 moves to the midbody to regulate cytokinesis mediated by nonmuscle myosin IIC.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mutations in UVSSA cause UV-sensitive syndrome and impair RNA polymerase IIo processing in transcription-coupled nucleotide-excision repair2012

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Three DNA polymerases, recruited by different mechanisms, carry out NER repair synthesis in human cells.2010

Author(s)

Journal Title

NAID

Data Source

[Journal Article] BRCA2 and nucleophosmin coregulate centrosome amplification and form a complex with ROCK2.2010

Author(s)

Journal Title

Data Source

[Journal Article] PTIP promotes DNA double-strand break repair through homologous recombination.2010

Author(s)

Journal Title

Data Source

[Journal Article] Introduction and characterization of a polymerase-dead point mutation into the POLK gene in vertebrates.2009

Author(s)

Journal Title

Data Source

[Journal Article] Genetic evidence for single-strand lesions initiating Nbs1-dependent homologous recombination in diversification of Ig V in chicken B lymphocytes.2009

Author(s)

Journal Title

Data Source

[Journal Article] Introduction and characterization of a polymerase-dead point mutation into the POLK gene in vertebrates2009

Author(s)

Journal Title

Data Source

[Journal Article] Involvement of vertebrate Polkappa in translesion DNA synthesis across DNA monoalkylation damage.2006

Author(s)

Journal Title

Description

TAKENAKA Katsuya 竹中克也

竹中克也タケナカカツヤ

[Presentation] 乳癌原因遺伝子BRCA2 新規結合分子の探索と相互作用が発癌に果たす分子機構の解明2012