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KOBAYASHI Yoshiyuki  小林 功幸

ORCIDConnect your ORCID iD *help
Researcher Number 20379746
External Links
Affiliation (based on the past Project Information) *help 2016: 東京医科大学, 医学部, 准教授
2015: 東京医科大学, 医学部, 講師
2010: 岡山大学, 病院, 助教
2009: 岡山大学, 大学病院, 助教
2007 – 2008: Okayama University, University Hospital, Assistant Professor
2005 – 2006: 岡山大学, 医学部・歯学部附属病院, 助手
Review Section/Research Field
Principal Investigator
Gastroenterology
Except Principal Investigator
Gastroenterology
Keywords
Principal Investigator
肝細胞癌 / ラジオ波焼灼療法 / 肝臓 / 肝癌 / 不可逆電気穿孔法 / metastasis / cell proliferation / vitamin K / hepatocellular carcinoma / 癌転移 / 細胞増殖 / ビタミンK … More
Except Principal Investigator
… More 血管新生 / 肝細胞癌 / 細胞増殖 Less
  • Research Projects

    (3 results)
  • Research Products

    (46 results)
  • Co-Researchers

    (8 People)
  •  肝細胞癌に対する不可逆電気穿孔法(IRE)における細胞死の分子機構と有効性の検討Principal Investigator

    • Principal Investigator
      小林 功幸
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Tokyo Medical University
  •  Novel mechanism for the angiogenesis in hepatocellular carcinoma

    • Principal Investigator
      SHIRAHA Hidenori
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Okayama University
  •  Effect of vitamin Kon cell growth in hepatocellular carcinoma.Principal Investigator

    • Principal Investigator
      KOBAYASHI Yoshiyuki
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Okayama University

All 2015 2011 2010 2008 2007 2006 2005

All Journal Article Presentation

  • [Journal Article] Assessment of various types of US findings after irreversible electroporation in porcine liver: comparison with radiofrequency ablation.2015

    • Author(s)
      Sugimoto K, Moriyasu F, Kobayashi Y
    • Journal Title

      J Vasc Interv Radiol.

      Volume: 26(2) Pages: 279-287

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09025
  • [Journal Article] Irreversible electroporation for nonthermal tumor ablation in patients with hepatocellular carcinoma: initial clinical experience in Japan.2015

    • Author(s)
      Sugimoto K, Moriyasu F, Kobayashi Y
    • Journal Title

      Jpn J Radiol

      Volume: 33(7) Pages: 424-432

    • NAID

      50009520610

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09025
  • [Journal Article] Loss of runt-related transcription factor 3 expression leads hepatocellular carcinoma cells to escape apoptosis.2011

    • Author(s)
      Nakanishi Y, Shiraha H, Ohnishi H, Nakamura S, Kobayashi Y, Yamamoto K, et.al.
    • Journal Title

      BMC Cancer 11巻

      Pages: 312-312

    • NAID

      120005053306

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590780
  • [Journal Article] Loss of runt-related transcription factor 3 expression leads hepatocellular carcinoma cells to escape apoptosis.2011

    • Author(s)
      Nakanishi Y, Shiraha H, Ohnishi H, Nakamura S, Kobayashi Y, Yamamoto K, et.al.
    • Journal Title

      BMC Cancer

      Volume: 11 Pages: 3-12

    • NAID

      120005053306

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590780
  • [Journal Article] Prognostic model for hepatocellular carcinoma with time-dependent factors.2011

    • Author(s)
      Kuwaki K, Kobayashi Y, Nakamura S, Onishi H, Shiraha H, Kobashi H, Yamamoto K, et.al.
    • Journal Title

      Acta Med Okayama 65(1)巻

      Pages: 11-19

    • NAID

      120002807407

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590780
  • [Journal Article] Prognostic model for hepatocellular carcinoma with time-dependent factors.2011

    • Author(s)
      Kuwaki K, Kobayashi Y, Nakamura S, Onishi H, Shiraha H, Kobashi H, Yamamoto K, et.al.
    • Journal Title

      Acta Med Okayama

      Volume: 65(1) Pages: 11-19

    • NAID

      120002807407

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590780
  • [Journal Article] Application of radiofrequency ablation for the treatment of metastatic liver cancers.2010

    • Author(s)
      Nouso K, Kobayashi Y, Nakamura S, Shiraha H, Yamamoto K, et.al.
    • Journal Title

      Hepatogastroenterology. 57(97)巻

      Pages: 117-120

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590780
  • [Journal Article] Time-dependent analysis of predisposing factors for the recurrence of hepatocellular carcinoma.2010

    • Author(s)
      Iwadou S, Kobayashi Y, Nakamura S, Ohnishi H, Shiraha H, Yamamoto K, et.al.
    • Journal Title

      Liver Int. 30(7)巻

      Pages: 1027-1032

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590780
  • [Journal Article] Application of radiofrequency ablation for the treatment of metastatic liver cancers.2010

    • Author(s)
      Nouso K, Kobayashi Y, Nakamura S, Shiraha H, Yamamoto K, et.al.
    • Journal Title

      Hepatogastroenterology.

      Volume: 57(97) Pages: 117-120

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590780
  • [Journal Article] Time-dependent analysis of predisposing factors for the recurrence of hepatocellular carcinoma.2010

    • Author(s)
      Iwadou S, Kobayashi Y, Nakamura S, Ohnishi H, Shiraha H, Yamamoto K, et.al.
    • Journal Title

      Liver Int.

      Volume: 30(7) Pages: 1027-1032

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590780
  • [Journal Article] Cost-effectiveness of the surveillance program of hepatocellular carcinoma depends on the medical circumstances.2008

    • Author(s)
      Nouso K, Kobayashi Y, et. al.
    • Journal Title

      Journal of Gastroenterology and Hepatology 23(3)

      Pages: 437-444

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590646
  • [Journal Article] Prognostic factors and treatment effects for hepatocellular carcinoma in Child C cirrhosis.2008

    • Author(s)
      Nouso k, Kobayashi Y, et. al.
    • Journal Title

      British Journal of Cancer (In Press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590646
  • [Journal Article] 肝がん診療におけるソナゾイド造影超音波検査の実際2008

    • Author(s)
      小林功幸、他
    • Journal Title

      インナービジョン 3

      Pages: 88-89

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590646
  • [Journal Article] Cost-effectiveness of the surveillance program of hepatocellular carcinoma depends on the medical circumstances2008

    • Author(s)
      Nouso, K., Kobayashi, Y., et. al.
    • Journal Title

      Journal of Gastroenterology and Hepatology 23-3

      Pages: 437-44

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590646
  • [Journal Article] 肝がん診療におけるソナゾイド造影超音波検査の実際2008

    • Author(s)
      小林功幸, 他
    • Journal Title

      インナービジョン 3

      Pages: 88-89

    • Data Source
      KAKENHI-PROJECT-17590646
  • [Journal Article] Standard therapy for Gastrointestinal cancer(in Japanese)2008

    • Author(s)
      Yagi, K., Kobayashi, Y
    • Journal Title

      Okayama Medical Journal 119

      Pages: 301-9

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590646
  • [Journal Article] US angiography(in Japanese)2008

    • Author(s)
      Kobayashi, Y., et. al.
    • Journal Title

      Inner Vision 3

      Pages: 88-9

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590646
  • [Journal Article] Risk factors for local and distant recurrence of hepatocellular carcinomas after local ablation therapies.2008

    • Author(s)
      Nouso K, Kobayashi Y, et. al.
    • Journal Title

      Journal of Gastroenterology and Hepatology 23(3)

      Pages: 453-458

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590646
  • [Journal Article] Prognostic factors and treatment effects for hepatocellular carcinoma in Child C cirrhosis2008

    • Author(s)
      Nouso, K., Kobayashi, Y., et. al.
    • Journal Title

      British Journal of Cancer (in Press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590646
  • [Journal Article] Prognostic factors and treatment effects for hepatocellular carcinoma in Child C cirrhosis.2008

    • Author(s)
      Nouso K, Kobayashi Y, et. al.
    • Journal Title

      British Journal of Cancer (In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590646
  • [Journal Article] 消化器癌の内科的標準治療2008

    • Author(s)
      八木 覚、小林功幸、他
    • Journal Title

      岡山医学会雑誌 119

      Pages: 301-309

    • NAID

      10020283015

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590646
  • [Journal Article] Risk factors for local and distant recurrence of hepatocellular carcinomas after local ablation therapies2008

    • Author(s)
      Nouso, K., Kobayashi, Y., et. al.
    • Journal Title

      Journal of Gastroenterology and Hepatology 23-3

      Pages: 453-8

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590646
  • [Journal Article] Risk factors for local and distant recurrence of hepatocellular carcinomasafter local ablation therapies.2008

    • Author(s)
      Nouso K, Kobayashi Y, et. al.
    • Journal Title

      Journal of Gastroenterology and Hepatology 23(3)

      Pages: 453-458

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590646
  • [Journal Article] 超音波画像診断マイクロコンベックスプローブの開発と肝癌診療における有用性2006

    • Author(s)
      中村進一郎, 小林功幸, 白鳥康史
    • Journal Title

      映像情報Medical 38

      Pages: 1346-1354

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590646
  • [Journal Article] Surveillance of hepatocellular carcinoma in patients with hepatitis C virus infection may improve patient survival2006

    • Author(s)
      Tanaka, H., Nouso, K., Kobashi, H., Kobayashi, Y., Nakamura, S., Miyake, Y., Ohnishi, H., Miyoshi, K., Iwado, S., Iwasaki, Y., Sakaguchi, K., Shiratori, Y
    • Journal Title

      Liver Int 26-5

      Pages: 543-51

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590646
  • [Journal Article] Surveillance of hepatocellular carcinoma in patients with hepatitis C virus infection may improve patient survival.2006

    • Author(s)
      Tanaka H, Nouso K, Kobashi H, Kobayashi Y, Nakamura S, Miyake Y, Ohnishi Y, Miyoshi K, Iwado S, Iwasaki Y, Sakaguchi K, Shiratori Y.
    • Journal Title

      Liver Int. 26・5

      Pages: 543-51

    • Data Source
      KAKENHI-PROJECT-17590646
  • [Journal Article] Sensitivity and specificity of des-gamma-carboxy prothrombin for diagnosis of patients with hepatocellular carcinomas varies according to tumor size2006

    • Author(s)
      Nakamura, S., Nouso, K., Sakaguchi, K., Ito, YM., Ohashi, Y., Kobayashi, Y., Toshikuni, N., Tanaka, H., Miyake, Y., Matsumoto, E., Shiratori, Y
    • Journal Title

      Am J Gastroenterol 101-9

      Pages: 2038-43

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590646
  • [Journal Article] Development of micro convex probe for diagnosis of hepatocellular carcinoma(in Japanese)2006

    • Author(s)
      Nakamura, S., Kobayashi, Y., Shiratori, Y
    • Journal Title

      Visual Medical 38

      Pages: 1346-54

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590646
  • [Journal Article] Sensitivity and specificity of des-gamma-carboxy prothrombin for diagnosis of patients with hepatocellular carcinomas varies according to tumor size.2006

    • Author(s)
      Nakamura S, Nouso K, Sakaguchi K, Ito YM, Ohashi Y, Kobayashi Y, Toshikuni N, Tanaka H, Miyake Y, Matsumoto E, Shiratori Y.
    • Journal Title

      Am J Gastroenterol. 101・9

      Pages: 2038-43

    • Data Source
      KAKENHI-PROJECT-17590646
  • [Journal Article] Surveillance of hepatocellular carcinoma in patients with hepatitis C virus infection may improve patient survival.2006

    • Author(s)
      Tanaka H, Nouso K, Kobashi H, Kobayashi Y, Nakamura S, Miyake Y, Ohnishi H, Miyoshi K, Iwado S, Iwasaki Y, Sakaguchi K, Shiratori Y.
    • Journal Title

      Liver Int. 26・5

      Pages: 543-51

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590646
  • [Journal Article] Sensitivity and specificity of des-gamma-carboxy prothrombin for diagnosis of patients with hepatocellular carcinomas varies according totumor size.2006

    • Author(s)
      Nakamura S, Nouso K, Sakaguchi K, Ito YM, Ohashi Y, Kobayashi Y, Toshikuni N, Tanaka H, Miyake Y, Matsumoto E. Shiratori Y.
    • Journal Title

      Am J Gastroenterol. 101・9

      Pages: 2038-43

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590646
  • [Journal Article] 超音波画像診断 マイクロコンベックスプローブの開発と肝癌診療における有用性2006

    • Author(s)
      中村進一郎, 小林功幸, 白鳥康史
    • Journal Title

      映像情報Medical 38

      Pages: 1346-1354

    • Data Source
      KAKENHI-PROJECT-17590646
  • [Journal Article] Diagnosis of Hepatocellular carcinoma (in Japanese)2005

    • Author(s)
      Kobayashi, Y., Sakaguchi, K., Nakamura, S., Tanaka, H., Shiratori, Y
    • Journal Title

      Laboratory examination 49

      Pages: 1201-5

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590646
  • [Journal Article] Altered expression of vascular endothelial growth factor, fibroblast growth factor-2 and endostatin in patients with hepatocellular carcinoma2005

    • Author(s)
      Uematsu, S., Kobayashi, Y., Shiratori, Y
    • Journal Title

      Journal of Gastroenterology and Hepatology 20-4

      Pages: 583-8

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590646
  • [Journal Article] Possible contribution of prior hepatitis B virus infection to the development of hepatocellular carcinoma.2005

    • Author(s)
      Tanaka H, Iwasaki Y, Kobayashi Y, Shiratori Y.
    • Journal Title

      Journal of Gastroenterology and Hepatology 20・6

      Pages: 850-6

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590646
  • [Journal Article] Altered expression of vascular endothelial growth factor, fibroblast growth factor-2 and endostatin in patients with hepatocellular carcinoma.2005

    • Author(s)
      Uematsu S, Kobayashi Y, Shiratori Y.
    • Journal Title

      Journal of Gastroenterology and Hepatology 20・4

      Pages: 583-8

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590646
  • [Journal Article] 肝臓癌の臨床検査:肝臓癌診断へのアプローチ.2005

    • Author(s)
      小林功幸、坂口孝作、中村進一郎、田中弘教、白鳥康史
    • Journal Title

      臨床検査 49

      Pages: 1201-1205

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590646
  • [Journal Article] Possible contribution of prior hepatitis B virus infection to the development of hepatocellular carcinoma2005

    • Author(s)
      Tanaka, H., Iwasaki, Y., Kobayashi, Y., Shiratori, Y
    • Journal Title

      Journal of Gastroenterology and Hepatology 20-6

      Pages: 850-6

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590646
  • [Journal Article] 肝臓癌の臨床検査:肝臓癌診断へのアプローチ2005

    • Author(s)
      小林功幸, 坂口孝作, 中村進一郎, 田中弘教, 白鳥康史
    • Journal Title

      臨床検査 49

      Pages: 1201-1205

    • Data Source
      KAKENHI-PROJECT-17590646
  • [Presentation] EFFECT OF IRREVERSIBLE ELECTROPORATION (IRE) ON THE PORCINE LIVER: COMPARISON WITH RADIOFREQUENCY ABLATION.2015

    • Author(s)
      Moriyasu F. Kobayashi Y.
    • Organizer
      EASL
    • Place of Presentation
      ウイーン
    • Year and Date
      2015-04-23
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09025
  • [Presentation] 肝癌に対する不可逆電気穿孔法(Irreversible Electroporation: IRE)の有効性:基礎的検討と臨床試験2015

    • Author(s)
      小林功幸
    • Organizer
      JDDW
    • Place of Presentation
      神戸市
    • Year and Date
      2015-10-09
    • Data Source
      KAKENHI-PROJECT-15K09025
  • [Presentation] 肝癌診療ガイドライン改訂に向けて 切除、ラジ波、移植の位置づけ 肝癌治療アルゴリズムにおけるラジオ波焼灼療法の適応 propensity analysisによる肝切除との比較2007

    • Author(s)
      小林功幸, 中村進一郎, 坂口孝作
    • Organizer
      Japan Digestive Disease Week 2007
    • Place of Presentation
      神戸
    • Year and Date
      2007-10-19
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590646
  • [Presentation] Therapy for hepatocellular carcinoma2007

    • Author(s)
      Kobayashi, Y., et. al.
    • Organizer
      Japan Digestive Disease Week 2007
    • Place of Presentation
      Kobe
    • Year and Date
      2007-09-19
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590646
  • [Presentation] How to treat hepatocellular carcinoma2007

    • Author(s)
      Kobayashi, Y., et. al.
    • Organizer
      Annual Meeting of Japan Society of Hepatology
    • Place of Presentation
      Tokyo
    • Year and Date
      2007-05-31
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590646
  • [Presentation] 肝癌診療ガイドライン改訂に向けて 切除、ラジオ波、移植の位置づけ肝癌治療アルゴリズムにおけるラジオ波焼灼療法の適応 propensity analsisによる肝切除との比較2007

    • Author(s)
      小林功幸, 中村進一郎, 坂口孝作
    • Organizer
      Japan Digestive Disease Week 2007
    • Place of Presentation
      神戸
    • Year and Date
      2007-10-19
    • Data Source
      KAKENHI-PROJECT-17590646
  • [Presentation] 肝癌診療のガイドラインの検証 肝細胞癌治療アルゴリズムの検証2007

    • Author(s)
      小林功幸, 中村進一郎, 坂口孝作
    • Organizer
      日本肝臓学会総会
    • Place of Presentation
      東京
    • Year and Date
      2007-05-31
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590646
  • 1.  SHIRAHA Hidenori (40379748)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 8 results
  • 2.  KOBASHI Haruhiko (00403486)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 3.  ONISHI Hideki (30595468)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 4.  NAKAMURA Shinichiro (70514230)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 5.  YAMAMOTO Kazuhide (90140491)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 6.  IWASAKI Yoshiaki (00314667)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 7.  杉本 勝俊 (20385032)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 8.  大城 久 (60381513)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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