Asamitsu Kaori 朝光かおり

… Alternative Names

朝光かおりアサミツカオリ

ASAMITSU Kaori 朝光かおり

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Researcher Number	20381783
Other IDs
Affiliation (Current)	2025: 名古屋市立大学, 医薬学総合研究院(医学), 講師
Affiliation (based on the past Project Information) *help	2019 – 2023: 名古屋市立大学, 医薬学総合研究院(医学), 講師 2017 – 2018: 名古屋市立大学, 大学院医学研究科, 講師 2010 – 2011: 名古屋市立大学, 大学院・医学研究科, 講師 2007 – 2009: Nagoya City University, 大学院・医学研究科, 助教 2005 – 2006: Nagoya City University, Graduate School of Medical Sciences, Research Associate, 大学院医学研究科, 助手 2004: 名古屋市立大学, 大学院・医学研究科, 助手
Review Section/Research Field	Principal Investigator General medical chemistry Except Principal Investigator Biological Sciences / Virology
Keywords	Principal Investigator 転写 / 発現制御 / NFκB / 転写因子 / Cyclin T1 / CDK9 / Tat / 転写制御 / P-TEFｂ / HIV / NF-κB / 生体分子医学 … More Except Principal Investigator … More HIV / Tat / NF-κB / OGG1 / maintenance of genome integrity / inhibitor / viral replication / transcriptional regulation / Bioinformatics / 分子モデリング / 立体構造解析 / RNA helicase A / HIV転写活性化 / 計算化学 / 立体構造 / AP-4 / IKK阻害剤 / ゲノム情報保持 / 阻害剤 / ウイルス複製 / 転写制御 / 転写機構 / クロマチン / HDAC / 潜伏感染 / Cyclin T1 / HIV-1 Less

The analysis of HIV transcriptional regulation and development of new HIV drugsPrincipal Investigator
- Principal Investigator
  
  Asamitsu Kaori
- Project Period (FY)
  2017 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Nagoya City University
Development of novel therapy against the transcriptional regulatory mechanism of human immunodeficiency virus(HIV).
- Principal Investigator
  
  OKAMOTO Takashi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  Nagoya City University
The analysis of NFκB regulation systemPrincipal Investigator
- Principal Investigator
  
  ASAMITSU Kaori
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Nagoya City University
新規NFκB相互作用分子による転写制御機構の解明Principal Investigator
- Principal Investigator
  
  朝光かおり
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Nagoya City University
Regulatory mechanism of HIV-ltranscription and its therapeutic control
- Principal Investigator
  
  OKAMOTO Takashi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  NAGOYA CITY UNIVERSTTY

All 2022 2020 2018 2017 2012 2011 2010 2009 2008 2007 2006

All Journal Article Presentation Book Patent

[Book] 転写因子・転写制御キーワードブック2006
- Author(s)
  朝光かおり
- Total Pages
  5
- Publisher
  用土社
- Data Source
  KAKENHI-PROJECT-18790208
[Journal Article] Identification of a novel CDK9 inhibitor targeting the intramolecular hidden cavity of CDK9 induced by Tat binding2022
- Author(s)
  Kaori Asamitsu, Takatsugu Hirokawa, Takashi Okamoto
- Journal Title
  
  PloS One
  
  Volume: 15 Issue: 11 Pages: e0277024-e0277024
- DOI
  10.1371/journal.pone.0277024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08638
[Journal Article] In Vitro Antiviral Activity of Mentha cordifolia Plant Extract in HIV-1 Latently Infected Cells Using an Established Human Cell Line2022
- Author(s)
  Sheriah Laine M de Paz-Silava, Ann Florence B Victoriano-Belvis, Nina G Gloriani, Yurina Hibi, Kaori Asamitsu, Takashi Okamoto
- Journal Title
  
  AIDS Res Hum Retroviruses
  
  Volume: 38 Issue: 1 Pages: 64-72
- DOI
  10.1089/aid.2021.0053
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08638
[Journal Article] Cancer-derived UTX TPR mutations G137V and D336G impair interaction with MLL3/4 complexes and affect UTX subcellular localization.2020
- Author(s)
  Kato H, Asamitsu K, Sun W, Kitajima S, Yoshizawa-Sugata N, Okamoto T, Masai H, Poellinger L
- Journal Title
  
  Oncogene.
  
  Volume: 39 Issue: 16 Pages: 3322-3335
- DOI
  10.1038/s41388-020-1218-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08638, KAKENHI-PROJECT-20K21410, KAKENHI-PROJECT-20KK0157, KAKENHI-PROJECT-17H01418, KAKENHI-PUBLICLY-19H05277, KAKENHI-PUBLICLY-20H05399, KAKENHI-PROJECT-20H00463
[Journal Article] HIV Tat/P-TEFb Interaction: A Potential Target for Novel Anti-HIV Therapies.2018
- Author(s)
  Asamitsu K, Fujinaga K, Okamoto T
- Journal Title
  
  Molecules
  
  Volume: 17 Issue: 4 Pages: 933-933
- DOI
  10.3390/molecules23040933
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08638
[Journal Article] The Tat/P-TEFb Protein-Protein Interaction Determining Transcriptional Activation of HIV.2017
- Author(s)
  Asamitsu K, Okamoto T.
- Journal Title
  
  Curr Pharm Des.
  
  Volume: 23 Issue: 28 Pages: 4091-4097
- DOI
  10.2174/1381612823666170710164148
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08638
[Journal Article] Functional characterization of human cyclin T1 N-terminal region for human immunodeficiency virus-1 Tat transcriptional activation2011
- Author(s)
  Asamitsu K, Hibi Y, Imai K, Victoriano AF, Kurimoto E, Kato K, Okamoto T
- Journal Title
  
  J Mol Biol
  
  Volume: 410 Pages: 887-895
- URL
  http://www.sciencedirect.com/science/article/pii/S0022283611004943
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390142
[Journal Article] Inhibition of inflammatory cytokine production from rheumatoid synovial fibroblasts by a novel IκB kinase inhibitor.2010
- Author(s)
  Tsuchiya, A., Imai, K., Asamitsu., K., Hibi, Y., Otsuka, T., Okamoto, T.
- Journal Title
  
  J Pharmacol Exp Ther (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790234
[Journal Article] A-kinase interacting protein 1(AKIP1)acts as a molecular determinant of PKA in NF-kB signaling2010
- Author(s)
  Nan Gao, Yurina Hibi, Marni Cueno, Kaori Asamitsu, Takashi Okamoto
- Journal Title
  
  J.Biol.Chem.
  
  Volume: 285 Pages: 28097-28104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390142
[Journal Article] Inhibition of inflammatory cytokine production from rheumatoid synovial fibroblasts by a novel IkappaB kinase inhibitor.2010
- Author(s)
  Tsuchiya A, Imai K, Asamitsu K, Waguri-Nagaya Y, Otsuka T, Okamoto T.
- Journal Title
  
  J Pharmacol Exp Ther. 333
  
  Pages: 236-243
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790234
[Journal Article] Protecting skin photoaging by NF-kB inhibitor2010
- Author(s)
  Kiyotaka Tanaka, Kaori Asamitsu, Hiroaki Uranishi, Arunasiri Iddamalgoda, Kenichi Ito, Hiroyuki Kojima, Takashi Okamoto
- Journal Title
  
  Curr Drug Metab.
  
  Volume: 11 Pages: 431-435
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390142
[Journal Article] Novel histone deacetylase inhibitor NCH-51 activates latent HIV-1 gene expression2010
- Author(s)
  Ann Florence B Victoriano, Hiraaki Togami, Takaharu Ueno, Kaori Asamitsu, Takayoshi Suzuki, Naoki Miyata, Kuniyasu Ochiai, Takashi Okamoto
- Journal Title
  
  FEBS Letters
  
  Volume: 585 Pages: 1103-1111
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390142
[Journal Article] Cychn T1 stabilizes expression levels of HIV-1 Tat in cells2009
- Author(s)
  Kenichi Imai, Kaori Asamitsu, Ann Florence B.Victoriano, Marni E.Cueno, Koh Fujinaga
- Journal Title
  
  FEBS J. 276
  
  Pages: 7124-33
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390142
[Journal Article] Inhibition of Inflammatory Cytokine Production from Rheumatoid Synovial Fibroblasts by a Novel IκB Kinase Inhibitor2009
- Author(s)
  Atsushi Tsuchiya, Kenichi Imai, Kaori Asamitsu, Yuko Waguri-Nagaya, Takanobu Otsuka, Takashi Okamoto
- Journal Title
  
  JPET 333
  
  Pages: 236-243
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390142
[Journal Article] Inhibition of human immunodeficiency virus type 1 replication by blocking IkappaB kinase with noraristeromycin.2008
- Author(s)
  Asamitsu, K, Yamaguchi, T., Nakata, K., Hibi, Y., Victoriano, A.F., Imai, K., Onozaki, K., Kitade, Y., Okamoto, T.
- Journal Title
  
  J Biochem. 144
  
  Pages: 581-589
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790234
[Journal Article] AKIP1 enhances NF-KB-dependent gene expression by promoting the nuclear retention and phosphorylation of p652008
- Author(s)
  Gao, N., Asamitsu, K., Hibi, Y., Ueno, T., and Okamoto, T
- Journal Title
  
  J.Biol.Chem 283
  
  Pages: 7834-7843
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790208
[Journal Article] Inhibition of human immunodeficiency virus type 1 replication by blockina IkannaB kinase with noraristeromvcin2008
- Author(s)
  Asamitsu, et.al.
- Journal Title
  
  J Biochem 144
  
  Pages: 581-589
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790234
[Patent] HIV複製阻害剤2012
- Inventor(s)
  岡本尚、朝光かおり、宮田直樹、鈴木孝禎
- Industrial Property Rights Holder
  岡本尚、朝光かおり、宮田直樹、鈴木孝禎
- Filing Date
  2012-02-23
- Overseas
- Data Source
  KAKENHI-PROJECT-21390142
[Patent] HIV複製阻害剤2012
- Inventor(s)
  岡本尚、朝光かおり、宮田直樹、鈴木孝禎
- Industrial Property Rights Holder
  岡本尚、朝光かおり、宮田直樹、鈴木孝禎
- Filing Date
  2012-02-23
- Data Source
  KAKENHI-PROJECT-21390142
[Patent] HIV複製阻害剤2012
- Inventor(s)
  岡本尚、朝光かおり、宮田直樹、鈴木孝禎
- Industrial Property Rights Holder
  岡本尚、朝光かおり、宮田直樹、鈴木孝禎
- Filing Date
  2012-02-23
- Overseas
- Data Source
  KAKENHI-PROJECT-21390142
[Patent] HIV増殖抑制剤2009
- Inventor(s)
  岡本尚, 朝光かおり, 日比悠里名
- Industrial Property Rights Holder
  名古屋市立大学
- Industrial Property Number
  2009-254740
- Filing Date
  2009-11-06
- Data Source
  KAKENHI-PROJECT-21390142
[Presentation] Tat特異的に誘導されるCDK9の局所構造（CDK9 hidden cavity）の構造特性と新規CDK阻害剤の探索2022
- Author(s)
  朝光かおり、広川貴次、岡本　尚
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-17K08638
[Presentation] 特異的CDK9ポケット構造を標的とした新規HIV治療薬の開発2020
- Author(s)
  朝光かおり、岡本　尚、広川貴次
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K08638
[Presentation] HIV-1 Tat enhances the stabilization of the HIV transcriptional activator complex by modifying its local structure.2017
- Author(s)
  朝光かおり、日比悠里名、岡本　尚
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K08638
[Presentation] Epigenetic Control of the HIV Latent Infection2011
- Author(s)
  Okamoto T, Victoriano AF, Asamitsu K, Imai K.
- Organizer
  6th German-Japanese HIV-Symposium
- Place of Presentation
  Bochum(German)
- Data Source
  KAKENHI-PROJECT-21390142
[Presentation] Epigenetic Control of the HIV Latent Infection2011
- Author(s)
  Takashi Okamoto, Ann Florence Victoriano, Kaori Asamitsu, Kenichi Imai
- Organizer
  6^<th> German-Japanese HIV-Symposium
- Place of Presentation
  Bochum (Germany)
- Data Source
  KAKENHI-PROJECT-21390142
[Presentation] Altered signaling cascade in ATL cell lines : implication for the development of anti-NF-κB therapy in ATL2011
- Author(s)
  Yurina Hibi, Kaori Asamitsu, Takashi Okamoto
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場・愛知
- Data Source
  KAKENHI-PROJECT-21390142
[Presentation] Involvement of the N-terminal region of human Cyclin T1 for the trans-activation of Human Immunodeficiency Virus-1 transcription by Tat2011
- Author(s)
  Asamitsu K, and Okamoto T.
- Organizer
  Transcription Elongation in Health and Disease
- Place of Presentation
  Lucca(Italy)
- Data Source
  KAKENHI-PROJECT-21390142
[Presentation] Involvement of the N-terminal region of human Cyclin T1 for the trans-activation of Human Immunodeficiency Virus-1 transcription by Tat2011
- Author(s)
  Kaori Asamitsu, Takashi Okamoto
- Organizer
  Transcription Elongation in Health and Disease
- Place of Presentation
  Lucca (Italy)
- Data Source
  KAKENHI-PROJECT-21390142
[Presentation] Development of anti-Tat drugs by in silico drug-screening using the predicted 3-D structure of Tat-TAR-cyclin T1 complex.2010
- Author(s)
  Takashi Okamoto, Yurina Hibi, Kaori Asamitsu
- Organizer
  12th Annual International Meeting of the Institute of Human Virology.
- Place of Presentation
  Tropea (Italy) (Sunshine Club Hotel White chest snc Loc)
- Data Source
  KAKENHI-PROJECT-21390142
[Presentation] Developing of small molecular weight anti-Tat drug using the predicted 3-D structure of Tat-TAR-cyclinT1 complex.2010
- Author(s)
  Takashi Okamoto, Yurina Hibi, Ann-Florence Victoriano, Kaori Asamitsu.
- Organizer
  5th German-Japanese HIV-SYMPOSIUM
- Place of Presentation
  東京(慶應大学三田キャンパス)
- Year and Date
  2010-05-10
- Data Source
  KAKENHI-PROJECT-21390142
[Presentation] HIVの転写活性化因子Tatと転写身長因子P-TEFbの相互作用の解析2010
- Author(s)
  Kaori Asamitsu, Yurina Hibi, Miyuki Sakai, Takashi Okamoto.
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会
- Place of Presentation
  神戸(神戸ポートアイランド)
- Data Source
  KAKENHI-PROJECT-21390142
[Presentation] HIV-1 TatとCyclinT1の相互作用の解析2009
- Author(s)
  朝光かおり, 日比悠里名, 小林雄祐, 岡本尚
- Organizer
  第23回日本エイズ学会学術集会・総会
- Place of Presentation
  名古屋国際会議場(名古屋市)
- Data Source
  KAKENHI-PROJECT-21390142
[Presentation] Identifi cation of an active ingredient on Inula helenium extracts for NF-κB inhibition2009
- Author(s)
  朝光かおり, 石橋貴宏, 田中清隆, 日比悠里名, 小林雄祐, 岡本尚
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Data Source
  KAKENHI-PROJECT-21390142
[Presentation] Identification of an active ingredient on Inula helenium extracts for NF-κB inhibition2009
- Author(s)
  Asamitsu, et al
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-20790234
[Presentation] HIVのTatによるウイルス転写活性化機構の解析2009
- Author(s)
  朝光かおり, 日比悠里名, 小林雄祐, 岡本尚
- Organizer
  第57回日本ウイルス学会学術集会
- Place of Presentation
  都市センターホテル(東京都)
- Data Source
  KAKENHI-PROJECT-21390142
[Presentation] Identification of an active ingredient on Inula helenium extracts for NF-kappa B inhibition2009
- Author(s)
  Asamitsu, K., Ishibashi, T., Tanaka, K., Hibi. Y., Kobayashi. Y., Okamoto. T.
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  パシフィコ横山
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-20790234
[Presentation] 炭素環ヌクレオシド化合物とセスキテルペン類による抗NF-κB活性の作用機序の解析2007
- Author(s)
  朝光かおり、田中清隆、石橋貴弘、中田賢治、岡本尚
- Organizer
  第28回日本炎症・再生医学会
- Place of Presentation
  京王プラザホテル(東京)
- Data Source
  KAKENHI-PROJECT-18790208
[Presentation] AKIP1 Enhances NF-KB Activation by Promoting the Nuclear Retention and Phosphorylation of p652007
- Author(s)
  Nan Gao, Kaori Asamitsu, Yurina Hibi, Takashi Okamoto
- Organizer
  第30回日本分子生物学会年会第80回日本生化学大会合同大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-18790208

1. OKAMOTO Takashi (40146600)

# of Collaborated Projects: 3 results

# of Collaborated Products: 24 results
2. KANAZAWA Satoshi (90347401)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Asamitsu Kaori 朝光 かおり

朝光 かおり アサミツ カオリ

ASAMITSU Kaori 朝光 かおり

Research Projects

Research Products

Co-Researchers

The analysis of HIV transcriptional regulation and development of new HIV drugsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of novel therapy against the transcriptional regulatory mechanism of human immunodeficiency virus(HIV).

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The analysis of NFκB regulation systemPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

新規NFκB相互作用分子による転写制御機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulatory mechanism of HIV-ltranscription and its therapeutic control

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] 転写因子・転写制御キーワードブック2006

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Identification of a novel CDK9 inhibitor targeting the intramolecular hidden cavity of CDK9 induced by Tat binding2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] In Vitro Antiviral Activity of Mentha cordifolia Plant Extract in HIV-1 Latently Infected Cells Using an Established Human Cell Line2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cancer-derived UTX TPR mutations G137V and D336G impair interaction with MLL3/4 complexes and affect UTX subcellular localization.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] HIV Tat/P-TEFb Interaction: A Potential Target for Novel Anti-HIV Therapies.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Tat/P-TEFb Protein-Protein Interaction Determining Transcriptional Activation of HIV.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Functional characterization of human cyclin T1 N-terminal region for human immunodeficiency virus-1 Tat transcriptional activation2011

Author(s)

Journal Title

URL

Data Source

[Journal Article] Inhibition of inflammatory cytokine production from rheumatoid synovial fibroblasts by a novel IκB kinase inhibitor.2010

Author(s)

Journal Title

Data Source

[Journal Article] A-kinase interacting protein 1(AKIP1)acts as a molecular determinant of PKA in NF-kB signaling2010

Author(s)

Journal Title

Data Source

[Journal Article] Inhibition of inflammatory cytokine production from rheumatoid synovial fibroblasts by a novel IkappaB kinase inhibitor.2010

Asamitsu Kaori 朝光かおり

朝光かおりアサミツカオリ

ASAMITSU Kaori 朝光かおり