SHIRAISHI Mitsuya 白石光也

… Alternative Names

Shiraishi Mitsuya 白石光也

白石光也シライシミツヤ

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Researcher Number	20383656
Other IDs
External Links
Affiliation (Current)	2025: 鹿児島大学, 農水産獣医学域獣医学系, 教授
Affiliation (based on the past Project Information) *help	2025: 鹿児島大学, 農水産獣医学域獣医学系, 教授 2019 – 2021: 鹿児島大学, 農水産獣医学域獣医学系, 教授 2015 – 2017: 鹿児島大学, 農水産獣医学域獣医学系, 准教授 2012 – 2014: 鹿児島大学, 獣医学部, 准教授 2011: 鹿児島大学, 農学部, 准教授 2005 – 2006: 北里大学, 薬学部, 助手
Review Section/Research Field	Principal Investigator Basic Section 42020:Veterinary medical science-related / Veterinary medical science / Basic veterinary science/Basic zootechnical science / Biological pharmacy
Keywords	Principal Investigator MARCKS / メチル水銀 / 培養神経細胞 / 細胞傷害機序 / 細胞分化 / ウイルス感染 / 発達神経毒性 / 有害金属 / 神経毒性 / SH-SY5Y … More / SH-SY5Y細胞 / 分化誘導 / 重金属 / カルパイン / 血管平滑筋 / 血小板 / 血管平滑筋細胞 / 血管内皮細胞 / 神経突起伸長 Less

Elucidation of virus susceptibility and cytotoxicity mechanisms in differentiated cultured neuronsPrincipal Investigator
- Principal Investigator
  
  白石光也
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Kagoshima University
Role of MARCKS protein on developmental neurotoxicity of toxic metalsPrincipal Investigator
- Principal Investigator
  
  Shiraishi Mitsuya
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Kagoshima University
Roles of MARCKS in platelets, smooth muscle and endothelial cells in haemostasis and thrombosisPrincipal Investigator
- Principal Investigator
  
  SHIRAISHI Mitsuya
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Veterinary medical science
- Research Institution
  Kagoshima University
Involvement of MARCKS on methylmercury neurotoxicity and application as a marker for neurotoxicityPrincipal Investigator
- Principal Investigator
  
  SHIRAISHI Mitsuya
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Basic veterinary science/Basic zootechnical science
- Research Institution
  Kagoshima University
神経突起伸長におけるMARCKS脱リン酸化の制御とその役割Principal Investigator
- Principal Investigator
  
  白石光也
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kitasato University

All 2021 2017 2016 2015 2014 2013 2012 2006 Other

All Journal Article Presentation

[Journal Article] Rho-kinase and the nitric oxide pathway modulate basilar arterial reactivity to acetylcholine and angiotensin II in streptozotocin-induced diabetic mice2017
- Author(s)
  Islam Md. Zahorul、Van Dao Cuong、Miyamoto Atsushi、Shiraishi Mitsuya
- Journal Title
  
  Naunyn-Schmiedeberg's archives of pharmacology
  
  Volume: 390 Issue: 9 Pages: 929-938
- DOI
  10.1007/s00210-017-1396-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26450407
[Journal Article] The MARCKS protein amount is differently regulated by calpain during toxic effects of methylmercury between SH-SY5Y and EA.hy926 cells2017
- Author(s)
  DAO Cuong Van、SHIRAISHI Mitsuya、MIYAMOTO Atsushi
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 79 Issue: 12 Pages: 1931-1938
- DOI
  10.1292/jvms.17-0473
- NAID
  130006246742
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26450407
[Journal Article] MARCKS is involved in methylmercury-induced decrease in cell viability and nitric oxide production in EA.hy926 cells2016
- Author(s)
  Cuong Van Dai, Md. Zahorul Islam, Kasumi Sudo, Mitsuya Shiraishi, Atsushi Miyamoto
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 78 Issue: 10 Pages: 1569-1576
- DOI
  10.1292/jvms.16-0249
- NAID
  130005267951
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26450407
[Journal Article] Methylmercury affects cerebrovascular reactivity to angiotensin II and acetylcholine via Rho-kinase and nitric oxide pathways in mice2016
- Author(s)
  Md. Zahorul Islam, Cuong Van Dao, Mitsuya Shiraishi, Atsushi Miyamoto
- Journal Title
  
  Life Sciences
  
  Volume: 147 Pages: 30-38
- DOI
  10.1016/j.lfs.2016.01.033
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26450407
[Journal Article] Heavy metal chelator TPEN attenuates fura-2 fluorescence changes induced by cadmium, mercury and methylmercury2016
- Author(s)
  Masato Ohkubo, Atsushi Miyamoto, Mitsuya Shiraishi
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 78 Issue: 5 Pages: 761-767
- DOI
  10.1292/jvms.15-0620
- NAID
  130005154285
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26450407
[Journal Article] Enzymatic synthesis and RNA interference of nucleosides incorporating stable isotopes into a base moiety2015
- Author(s)
  Akihiko Hatano, Mitsuya Shiraishi, Nanae Terado, Atsuhiro Tanabe, Kenji Fukuda
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 23 Issue: 20 Pages: 6683-6688
- DOI
  10.1016/j.bmc.2015.09.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26450407
[Journal Article] Alteration in MARCKS phosphorylation and expression by methylmercury in SH-SY5Y cells and rat brain2014
- Author(s)
  Mitsuya Shiraishi, Makoto Hangai, Megumi Yamamoto, Masanori Sasaki, Atsuhiro Tanabe, Yasuharu Sasaki, Atsushi Miyamoto
- Journal Title
  
  Environ Toxicol. Pharmacol.
  
  Volume: 37 Pages: 1256-1263
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23780298
[Journal Article] Increased expression of aquaporin-4 with methylmercury exposure in the brain of the common marmoset2012
- Author(s)
  Yamamoto, M., Takeya, M., Ikeshima-Kataoka, H., Yasui, M., Kawasaki, Y., Shiraishi, M., Majima, E., Shiraishi, S., Uezono, Y., Sasaki, M., Eto, K.
- Journal Title
  
  The Journal of Toxicological Sciences
  
  Volume: 37 Issue: 4 Pages: 749-763
- DOI
  10.2131/jts.37.749
- NAID
  10030502324
- ISSN
  0388-1350, 1880-3989
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23780298
[Journal Article] MARCKS dephosphorylation is involved in bradykinin-induced neurite outgrowth in neuroblastoma SH-SY5Y cells.2012
- Author(s)
  Tanabe A, Shiraishi M, Negishi M, Saito N, Tanabe M, and Sasaki Y.
- Journal Title
  
  J Cell Physiol.
  
  Volume: 227 Issue: 2 Pages: 618-629
- DOI
  10.1002/jcp.22763
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659137, KAKENHI-PROJECT-23780298, KAKENHI-PUBLICLY-23113511
[Journal Article] Unphosphorylated MARCKS is involved in neurite initiation induced by insulin-like growth factor-I in SH-SY5Y cells2006
- Author(s)
  Shiraishi, M.
- Journal Title
  
  Journal of Cellular Physiology 209(3)
  
  Pages: 1029-1038
- Data Source
  KAKENHI-PROJECT-17790071
[Presentation] 未分化型および分化型ヒト由来培養神経細胞におけるウイルス感受性の比較2021
- Author(s)
  牧野遥、正谷達謄、藤本佳万、内藤清惟、白石光也
- Organizer
  第164回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-19K06404
[Presentation] メチル水銀毒性におけるカルパイン活性化とMARCKS発現量の制御2017
- Author(s)
  白石光也, Cuong Van DAO, 宮本篤
- Organizer
  第44回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-26450407
[Presentation] メチル水銀の毒性発現機構：血管収縮機能への影響とそのシグナル伝達機構2017
- Author(s)
  白石光也
- Organizer
  第59回日本平滑筋学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-26450407
[Presentation] Cleavage of MARCKS by calpain is involved in cytotoxicity of methylmercury in SH-SY5Y cells2017
- Author(s)
  Cuong Dao, 白石光也, 宮本篤
- Organizer
  第160回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-26450407
[Presentation] MARCKSタンパク質を介するメチル水銀毒性におけるカルパインの関与2017
- Author(s)
  白石光也, Dao Van Cuong, 宮本篤
- Organizer
  第70回日本薬理学会西南部会
- Data Source
  KAKENHI-PROJECT-26450407
[Presentation] メチル水銀の細胞毒性－神経細胞と血管内皮細胞－2017
- Author(s)
  白石光也
- Organizer
  第76回日本公衆衛生学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-26450407
[Presentation] Role of MARCKS in endothelial cell functions and involvement in methylmercury toxicity2016
- Author(s)
  Cuong V. Dao, Atsushi Miyamoto, Mitsuya Shiraishi
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-03-11
- Data Source
  KAKENHI-PROJECT-26450407
[Presentation] メチル水銀毒性におけるMARCKSタンパク質の関与とそのリン酸化動態への影響2016
- Author(s)
  白石光也
- Organizer
  平成27年度メチル水銀研究ミーティング
- Place of Presentation
  LMJ東京研修センター（東京都・文京区）
- Year and Date
  2016-01-07
- Invited
- Data Source
  KAKENHI-PROJECT-26450407
[Presentation] メチル水銀による血管内皮細胞機能の障害とMARCKSタンパク質の関与2016
- Author(s)
  白石光也
- Organizer
  平成28年度メチル水銀研究ミーティング
- Place of Presentation
  LMJ東京研修センター（東京都・文京区）
- Year and Date
  2016-12-26
- Invited
- Data Source
  KAKENHI-PROJECT-26450407
[Presentation] Effect of in vivo exposure of low concentration of methylmercury on the cardiovascular system in adult mice2015
- Author(s)
  Md. Zahorul Islam, Cuong V. Dao, 白石光也, 宮本篤
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場（愛知県、名古屋市）
- Year and Date
  2015-03-19
- Data Source
  KAKENHI-PROJECT-26450407
[Presentation] Effect of methylmercury exposure during fetal and lactation period on the cardiovascular system in mice2015
- Author(s)
  Cuong. V. Dao, Md. Zhahorul Islam, 宮本篤, 白石光也
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場（愛知県、名古屋市）
- Year and Date
  2015-03-19
- Data Source
  KAKENHI-PROJECT-26450407
[Presentation] Toxic effects of methylmercury on endothelial cell function and involvement of MARCKS2015
- Author(s)
  Cuong Dao Van, 白石光也, 宮本篤
- Organizer
  第158回日本獣医学会学術集会
- Place of Presentation
  北里大学（青森県・十和田市）
- Year and Date
  2015-09-08
- Data Source
  KAKENHI-PROJECT-26450407
[Presentation] Analysis of intracellular calcium mobilization induced by heavy metals using fura-2 and TPEN in SH-SY5Y cells2014
- Author(s)
  大久保正人,宮本篤,白石光也
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台市
- Year and Date
  2014-03-19
- Data Source
  KAKENHI-PROJECT-23780298
[Presentation] Methylmercury affects cerebrovascular reactivities to angiotensin II and acetylcholine via rho-kinase and NO pathways2014
- Author(s)
  Islam Md. Zahoru, Dao Van Cuong, 白石光也，宮本篤
- Organizer
  第157回日本獣医学会学術集会
- Place of Presentation
  北海道大学（北海道、札幌市）
- Year and Date
  2014-09-20
- Data Source
  KAKENHI-PROJECT-26450407
[Presentation] Alteration of MARCKS Expression and Phosphorylation Levels by Methylmercury2013
- Author(s)
  Mitsuya Shiraishi, Makoto Hangai, Megumi Yamamoto, Atsuhiro Tanabe, Atsushi Miyamoto
- Organizer
  The XIII International Congress of Toxicology
- Place of Presentation
  Seoul, Korea
- Year and Date
  2013-07-02
- Data Source
  KAKENHI-PROJECT-23780298
[Presentation] 重金属による細胞内カルシウム濃度の変化とその特徴2013
- Author(s)
  大久保正人,宮本篤,白石光也
- Organizer
  第155回日本獣医学会学術集会
- Place of Presentation
  東京都
- Year and Date
  2013-03-30
- Data Source
  KAKENHI-PROJECT-23780298
[Presentation] メチル水銀の細胞毒性発現におけるMARCKSの役割2013
- Author(s)
  白石光也,半谷誠,佐々木眞敬,宮本篤
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡市
- Year and Date
  2013-03-22
- Data Source
  KAKENHI-PROJECT-23780298
[Presentation] メチル水銀によるMARCKSリン酸化機序と毒性発現との関連2012
- Author(s)
  白石光也,半谷誠,佐々木眞敬,宮本篤
- Organizer
  第154回日本獣医学会学術集会
- Place of Presentation
  盛岡市
- Year and Date
  2012-09-16
- Data Source
  KAKENHI-PROJECT-23780298
[Presentation] メチル水銀の細胞毒性発現におけるMARCKSの役割．
- Author(s)
  白石光也，半谷誠，佐々木眞敬，宮本篤．
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡国際会議場（福岡市）
- Data Source
  KAKENHI-PROJECT-23780298
[Presentation] SH-SY5Y細胞におけるfura-2とTPENを用いた重金属誘導細胞内カルシウム動員の解析
- Author(s)
  大久保正人，宮本篤，白石光也
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台国際センター（仙台市）
- Data Source
  KAKENHI-PROJECT-23780298
[Presentation] Alteration of MARCKS Expression and Phosphorylation Levels by Methylmercury
- Author(s)
  Mitsuya Shiraishi, Makoto Hangai, Megumi Yamamoto, Atsuhiro Tanabe, Atsushi Miyamoto
- Organizer
  The XIII International Congress of Toxicology
- Place of Presentation
  Coex (Seoul), Korea
- Data Source
  KAKENHI-PROJECT-23780298
[Presentation] MPP+誘導性アポトーシスに対するMARCKSの関与．
- Author(s)
  田辺敦弘，桜井祥太，白石光也，佐々木泰治．
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Data Source
  KAKENHI-PROJECT-23780298
[Presentation] 重金属による細胞内カルシウム濃度の変化とその特徴．
- Author(s)
  大久保正人，宮本篤，白石光也．
- Organizer
  第155回日本獣医学会学術集会
- Place of Presentation
  東京大学駒場キャンパス（東京都）
- Data Source
  KAKENHI-PROJECT-23780298
[Presentation] メチル水銀によるMARCKSリン酸化機序と毒性発現との関連．
- Author(s)
  白石光也，半谷誠，佐々木眞敬，宮本篤．
- Organizer
  第154回日本獣医学会学術集会
- Place of Presentation
  岩手大学（盛岡市）
- Data Source
  KAKENHI-PROJECT-23780298
[Presentation] ブラジキニン刺激による神経突起伸長へのMARCKSリン酸化/脱リン酸化の関与．
- Author(s)
  田辺敦弘, 白石光也, 佐々木泰治．
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場（福岡市）
- Data Source
  KAKENHI-PROJECT-23780298

1. MIYAMOTO Atsushi (70219806)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
2. 斎藤尚亮

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SHIRAISHI Mitsuya 白石 光也

Shiraishi Mitsuya 白石 光也

白石 光也 シライシ ミツヤ

Research Projects

Research Products

Co-Researchers

Elucidation of virus susceptibility and cytotoxicity mechanisms in differentiated cultured neuronsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of MARCKS protein on developmental neurotoxicity of toxic metalsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Roles of MARCKS in platelets, smooth muscle and endothelial cells in haemostasis and thrombosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Involvement of MARCKS on methylmercury neurotoxicity and application as a marker for neurotoxicityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

神経突起伸長におけるMARCKS脱リン酸化の制御とその役割Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Rho-kinase and the nitric oxide pathway modulate basilar arterial reactivity to acetylcholine and angiotensin II in streptozotocin-induced diabetic mice2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The MARCKS protein amount is differently regulated by calpain during toxic effects of methylmercury between SH-SY5Y and EA.hy926 cells2017

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] MARCKS is involved in methylmercury-induced decrease in cell viability and nitric oxide production in EA.hy926 cells2016

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Methylmercury affects cerebrovascular reactivity to angiotensin II and acetylcholine via Rho-kinase and nitric oxide pathways in mice2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Heavy metal chelator TPEN attenuates fura-2 fluorescence changes induced by cadmium, mercury and methylmercury2016

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Enzymatic synthesis and RNA interference of nucleosides incorporating stable isotopes into a base moiety2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Alteration in MARCKS phosphorylation and expression by methylmercury in SH-SY5Y cells and rat brain2014

Author(s)

Journal Title

Data Source

[Journal Article] Increased expression of aquaporin-4 with methylmercury exposure in the brain of the common marmoset2012

SHIRAISHI Mitsuya 白石光也

Shiraishi Mitsuya 白石光也

白石光也シライシミツヤ